Page last updated: 2024-08-23

heme and Cerebral Hemorrhage

heme has been researched along with Cerebral Hemorrhage in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's2 (8.00)18.2507
2000's3 (12.00)29.6817
2010's14 (56.00)24.3611
2020's5 (20.00)2.80

Authors

AuthorsStudies
Ek, J; Hagberg, H; Nilsson, G; Rocha-Ferreira, E; Song, J; Wang, X; Wang, Y; Xu, Y; Zelco, A; Zhang, S; Zhang, X; Zhu, C1
Gao, S; Liu, K; Nishibori, M; Ousaka, D; Qiao, H; Takada, K; Teshigawara, K; Wang, D; Wang, Z; Zhao, K1
Al-Shahi Salman, R; Hardingham, GE; Loan, JJM; McColl, BW1
Guo, T; Hu, J; Ling, Y; Lv, X; Ni, Y; Niu, D; Qiu, Y; Si, Y; Wang, Z; Zeng, Y; Zhang, J1
Cao, Y; Chen-Roetling, J; Li, Y; Lu, X; Regan, RF; Yan, Z1
Cho, IH; Choi, B; Jang, YH; Lee, SJ; Min, H1
Bozza, FA; Bozza, M; Faria Neto, HCC; Freitas, G; Japiassú, AM; Oliveira, MF; Righy, C; Turon, R1
Budbazar, E; Guo, Z; Krafft, PR; Tang, J; Tong, L; Wang, G; Xue, F; Zhang, JH1
Bewer, B; Caine, S; Colbourne, F; DeSouza, M; Hackett, MJ; Nichol, H; Paterson, PG1
Gan, Q; Hu, X; Li, H; Tao, C; You, C; Zheng, J1
Budbazar, E; Manaenko, A; Nowrangi, D; Ou, Y; Shao, A; Tang, J; Wang, G; Yang, P; Zhang, JH1
Clark, JF; Hansen, C; Loftspring, MC1
Li, JC; Liang, H; Lin, S; Lu, FL; Wang, JZ; Xiong, KL; Yang, QW; Zhong, Q; Zhou, Y1
Katsuki, H1
Chen, L; Chen-Roetling, J; Regan, RF; Zhang, X1
Dave, JR; Lu, XC; Tortella, FC; Wei, G; Yang, W; Yao, C1
Li, JQ; Lin, S; Lv, FL; Su, BY; Wang, JZ; Yang, QW; Yin, Q; Zhong, Q; Zhou, Y1
Foerch, C; Kashefiolasl, S; Pfeilschifter, W1
Davis, T; Hahl, P; Rogers, JT; Smith, A; Washburn, C1
Ardizzone, TD; Clark, JF; Lu, A; Sharp, FR; Wagner, KR1
Cullen, KM; Kócsi, Z; Stone, J1
Benvenisti-Zarom, L; Regan, RF1
Atlas, SW; Thulborn, KR1
Auer, C; Conrad, B; Gräflin von Einsiedel, H; Siebner, HR; Wilhelm, T1
Lindquist, C; Wahlgren, NG1

Reviews

5 review(s) available for heme and Cerebral Hemorrhage

ArticleYear
Temporal brain transcriptome analysis reveals key pathological events after germinal matrix hemorrhage in neonatal rats.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2022, Volume: 42, Issue:9

    Topics: Animals; Animals, Newborn; Brain; Brain Injuries; Cerebral Hemorrhage; Gene Expression Profiling; Heme; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Inflammation; Rats; Transcriptome

2022
Activation of Nrf2 to Optimise Immune Responses to Intracerebral Haemorrhage.
    Biomolecules, 2022, 10-07, Volume: 12, Issue:10

    Topics: Antioxidants; Cerebral Hemorrhage; Cytokines; Hematoma; Heme; Hemostatics; Humans; NF-E2-Related Factor 2; Phagocytosis

2022
Oxidative Stress in Intracerebral Hemorrhage: Sources, Mechanisms, and Therapeutic Targets.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Animals; Brain Injuries; Cerebral Hemorrhage; Heme; Hemoglobins; Humans; Inflammation; Iron; Mice; Mitochondria; NADPH Oxidases; NF-E2-Related Factor 2; Nitric Oxide Synthase; Oxidative Stress; Oxygen; Prognosis; Signal Transduction; Stroke; Superoxide Dismutase

2016
Exploring neuroprotective drug therapies for intracerebral hemorrhage.
    Journal of pharmacological sciences, 2010, Volume: 114, Issue:4

    Topics: Animals; Cerebral Hemorrhage; Cytokines; Drug Design; Free Radical Scavengers; Glutamates; Heme; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Intercellular Signaling Peptides and Proteins; Ligands; Matrix Metalloproteinases; Minocycline; Neuroprotective Agents; Receptors, Cytoplasmic and Nuclear; Thrombin

2010
Heme and iron metabolism: role in cerebral hemorrhage.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2003, Volume: 23, Issue:6

    Topics: Animals; Brain; Cerebral Hemorrhage; Heme; Humans; Iron

2003

Other Studies

20 other study(ies) available for heme and Cerebral Hemorrhage

ArticleYear
Treatment of Marmoset Intracerebral Hemorrhage with Humanized Anti-HMGB1 mAb.
    Cells, 2022, 09-23, Volume: 11, Issue:19

    Topics: Animals; Antibodies, Monoclonal, Humanized; Brain Injuries; Callithrix; Cerebral Hemorrhage; Cytokines; Haptoglobins; Heme; HMGB1 Protein; Iron; Rats; Rats, Wistar

2022
Human Neural Stem Cell Secretome Inhibits Neuron Heme Uptake and Ferroptosis in Intracerebral Hemorrhage Through Nrf-2 Signaling Pathway.
    Stem cells and development, 2023, Volume: 32, Issue:11-12

    Topics: Animals; Cerebral Hemorrhage; Ferroptosis; Heme; Hemin; Humans; Mice; Neural Stem Cells; Neurons; Secretome; Signal Transduction

2023
Effect of hemopexin treatment on outcome after intracerebral hemorrhage in mice.
    Brain research, 2021, 08-15, Volume: 1765

    Topics: Animals; Blood-Brain Barrier; Brain; Cell Death; Cerebral Hemorrhage; Corpus Striatum; Disease Models, Animal; Female; Heme; Heme Oxygenase-1; Hemoglobins; Hemopexin; Injections, Intraperitoneal; Male; Mice; Treatment Outcome

2021
Heme molecule functions as an endogenous agonist of astrocyte TLR2 to contribute to secondary brain damage after intracerebral hemorrhage.
    Molecular brain, 2017, 06-24, Volume: 10, Issue:1

    Topics: Animals; Astrocytes; Blood-Brain Barrier; Brain Injuries; Cerebral Hemorrhage; Heme; Inflammation; Male; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; Toll-Like Receptor 2

2017
Hemoglobin metabolism by-products are associated with an inflammatory response in patients with hemorrhagic stroke.
    Revista Brasileira de terapia intensiva, 2018, Volume: 30, Issue:1

    Topics: Aged; Brain; Cerebral Hemorrhage; Cohort Studies; Female; Heme; Hemoglobins; Hemopexin; Humans; Inflammation; Male; Middle Aged; Prospective Studies; Stroke; Subarachnoid Hemorrhage

2018
TLR7 (Toll-Like Receptor 7) Facilitates Heme Scavenging Through the BTK (Bruton Tyrosine Kinase)-CRT (Calreticulin)-LRP1 (Low-Density Lipoprotein Receptor-Related Protein-1)-Hx (Hemopexin) Pathway in Murine Intracerebral Hemorrhage.
    Stroke, 2018, Volume: 49, Issue:12

    Topics: Agammaglobulinaemia Tyrosine Kinase; Amides; Animals; Blood-Brain Barrier; Brain; Brain Edema; Calreticulin; Cerebral Hemorrhage; Enzyme Inhibitors; Heme; Hemopexin; Imiquimod; Low Density Lipoprotein Receptor-Related Protein-1; Membrane Glycoproteins; Mice; Nitriles; Oligodeoxyribonucleotides; Receptors, LDL; Signal Transduction; Thapsigargin; Toll-Like Receptor 7; Tumor Suppressor Proteins

2018
A new method to image heme-Fe, total Fe, and aggregated protein levels after intracerebral hemorrhage.
    ACS chemical neuroscience, 2015, May-20, Volume: 6, Issue:5

    Topics: Animals; Cerebral Hemorrhage; Disease Models, Animal; Heme; Iron; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Spectrometry, X-Ray Emission; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spectrum Analysis, Raman

2015
Low-density lipoprotein receptor-related protein-1 facilitates heme scavenging after intracerebral hemorrhage in mice.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017, Volume: 37, Issue:4

    Topics: Animals; Behavior, Animal; Blood-Brain Barrier; Capillary Permeability; Cerebral Hemorrhage; Heme; Hemopexin; Low Density Lipoprotein Receptor-Related Protein-1; Male; Mice, Inbred Strains; Neuroprotective Agents; Receptors, LDL; Recombinant Proteins; Tumor Suppressor Proteins

2017
A novel brain injury mechanism after intracerebral hemorrhage: the interaction between heme products and the immune system.
    Medical hypotheses, 2010, Volume: 74, Issue:1

    Topics: Animals; Astrocytes; Bilirubin; Brain; Brain Injuries; Cerebral Hemorrhage; Endothelial Cells; Heme; Humans; Immune System; Leukocytes; Mice; Models, Biological; Models, Theoretical; Neuroglia

2010
Elevation of high-mobility group protein box-1 in serum correlates with severity of acute intracerebral hemorrhage.
    Mediators of inflammation, 2010, Volume: 2010

    Topics: Animals; Cells, Cultured; Cerebral Hemorrhage; Female; Heme; HMGB1 Protein; Humans; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Microglia; Stroke; Tumor Necrosis Factor-alpha

2010
Increased striatal injury and behavioral deficits after intracerebral hemorrhage in hemopexin knockout mice.
    Journal of neurosurgery, 2011, Volume: 114, Issue:4

    Topics: Animals; Behavior, Animal; Cell Survival; Cerebral Hemorrhage; Corpus Striatum; Genotype; Haptoglobins; Heme; Hemoglobins; Hemopexin; Mice; Mice, Knockout; Motor Activity; Nerve Tissue Proteins; Oxidation-Reduction; Psychomotor Performance; Reverse Transcriptase Polymerase Chain Reaction

2011
Selective brain cooling in rats ameliorates intracerebral hemorrhage and edema caused by penetrating brain injury: possible involvement of heme oxygenase-1 expression.
    Journal of neurotrauma, 2011, Volume: 28, Issue:7

    Topics: Animals; Body Water; Brain Edema; Cerebral Hemorrhage; Disease Models, Animal; Down-Regulation; Head Injuries, Penetrating; Heme; Heme Oxygenase (Decyclizing); Hypothermia, Induced; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Up-Regulation

2011
Heme activates TLR4-mediated inflammatory injury via MyD88/TRIF signaling pathway in intracerebral hemorrhage.
    Journal of neuroinflammation, 2012, Mar-06, Volume: 9

    Topics: Adaptor Proteins, Vesicular Transport; Animals; Animals, Newborn; Antibodies, Monoclonal; Cells, Cultured; Cerebral Cortex; Cerebral Hemorrhage; Cytokines; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Heme; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Myeloid Differentiation Factor 88; Neurologic Examination; NF-kappa B; RNA, Messenger; Signal Transduction; Statistics, Nonparametric; Time Factors; Toll-Like Receptor 4; Up-Regulation

2012
Graphite furnace atomic absorption spectrophotometry--a novel method to quantify blood volume in experimental models of intracerebral hemorrhage.
    Journal of neuroscience methods, 2013, Feb-15, Volume: 213, Issue:1

    Topics: Animals; Blood Volume; Blood Volume Determination; Cerebral Hemorrhage; Evans Blue; Heme; Hemoglobins; Male; Mice; Mice, Inbred C57BL; Photometry; Reference Standards; Spectrophotometry, Atomic; User-Computer Interface

2013
Mechanisms of neuroprotection by hemopexin: modeling the control of heme and iron homeostasis in brain neurons in inflammatory states.
    Journal of neurochemistry, 2013, Volume: 125, Issue:1

    Topics: Amyloid beta-Protein Precursor; Apoproteins; Brain; Brain Injuries; Cell Line, Tumor; Cerebral Hemorrhage; Endocytosis; Enzyme Induction; Heme; Heme Oxygenase-1; Hemopexin; Humans; Inflammation; Neurons; Peroxides; Reactive Oxygen Species

2013
Pericapillary haem-rich deposits: evidence for microhaemorrhages in aging human cerebral cortex.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2005, Volume: 25, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Capillaries; Cerebral Cortex; Cerebral Hemorrhage; Collagen Type IV; Dementia, Vascular; Erythrocytes; Factor VIII; Female; Fibrinogen; Heme; Humans; Male; Middle Aged

2005
Astrocyte-specific heme oxygenase-1 hyperexpression attenuates heme-mediated oxidative injury.
    Neurobiology of disease, 2007, Volume: 26, Issue:3

    Topics: Animals; Astrocytes; Brain; Brain Damage, Chronic; Cell Death; Cells, Cultured; Cerebral Hemorrhage; Cytoprotection; Gene Expression Regulation, Enzymologic; Genetic Vectors; Heme; Heme Oxygenase-1; Humans; Mice; Mice, Inbred BALB C; Mice, Transgenic; Nerve Degeneration; Oxidative Stress; Promoter Regions, Genetic; Transfection; Up-Regulation

2007
MR detection of hyperacute parenchymal hemorrhage of the brain.
    AJNR. American journal of neuroradiology, 1998, Volume: 19, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Animals; Brain; Cerebral Hemorrhage; Cerebrovascular Disorders; Child; Child, Preschool; Disease Models, Animal; Female; Ferritins; Hematoma; Heme; Humans; Iron; Magnetic Resonance Imaging; Male; Middle Aged; Rats; Retrospective Studies

1998
[The "heme"-sequence (T2*-weighted gradient echo magnetic resonance tomography). Value in differential spontaneous intracerebral hemorrhage diagnosis].
    Der Nervenarzt, 1999, Volume: 70, Issue:8

    Topics: Aged; Brain; Cerebral Hemorrhage; Diagnosis, Differential; Female; Follow-Up Studies; Heme; Hemosiderin; Humans; Image Enhancement; Magnetic Resonance Imaging; Male; Middle Aged; Recurrence; Spinal Cord

1999
Haem derivatives in the cerebrospinal fluid after intracranial haemorrhage.
    European neurology, 1987, Volume: 26, Issue:4

    Topics: Bilirubin; Cerebral Hemorrhage; Cerebrospinal Fluid Proteins; Erythrocyte Count; Heme; Hemolysis; Humans; Methemoglobin; Oxyhemoglobins; Time Factors

1987