harmine has been researched along with Osteolysis* in 1 studies
1 other study(ies) available for harmine and Osteolysis
Article | Year |
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Harmine Alleviates Titanium Particle-Induced Inflammatory Bone Destruction by Immunomodulatory Effect on the Macrophage Polarization and Subsequent Osteogenic Differentiation.
Peri-prosthetic osteolysis (PPO) and following aseptic loosening are regarded as the prime reasons for implant failure after joint replacement. Increasing evidence indicated that wear-debris-irritated inflammatory response and macrophage polarization state play essential roles in this osteolytic process. Harmine, a β-carboline alkaloid primitively extracted from the Topics: Animals; Biomarkers; Bone Diseases; Cell Survival; Disease Models, Animal; Fluorescent Antibody Technique; Harmine; Immunohistochemistry; Inflammation; Macrophage Activation; Macrophages; Male; Mice; Nitric Oxide; Osteoclasts; Osteogenesis; Osteolysis; RAW 264.7 Cells; Titanium; X-Ray Microtomography | 2021 |