harmine has been researched along with Hemolysis* in 2 studies
2 other study(ies) available for harmine and Hemolysis
| Article | Year |
|---|---|
Preparation of hyaluronic acid-loaded Harmine polymeric micelles and in vitro effect anti-breast cancer.
To prepare hyaluronic acid-loaded Harmine polymeric micelles with CD. The carboxyl group on hyaluronic acid is coupled to the amino group on 3,5-bis(trifluoromethyl)benzylamine by an amidation reaction. And the polymeric micelles self-assemble to encapsulate the Harmine in a hydrophobic core, characterized the polymer micelles by IR,. The prepared polymer micelles had a uniform particle size of about 200 nm, good dispersion, PDI < 0.3, encapsulation rate up to 87%, drug loading of 4.12±0.03%, and negative charge. Hyaluronidase has a good enzymatic effect on polymeric micelles, with a hemolysis rate of less than 1%. It showed some dose-dependent toxicity to both MDA-MB-231 and MCF-7, with increased uptake of polymer micelles by CD Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Female; Harmine; Hemolysis; Humans; Hyaluronic Acid; MCF-7 Cells; Micelles; Polymers | 2023 |
[Effects of harmine on immune function in mice].
Topics: Alkaloids; Animals; Female; Harmine; Hemolysis; Hypersensitivity, Delayed; Lymphocyte Activation; Male; Mice; Phagocytosis | 1987 |