harman and Pain

harman has been researched along with Pain* in 2 studies

Other Studies

2 other study(ies) available for harman and Pain

Article	Year
Effect of harmane on mononeuropathic pain in rats. Annals of the New York Academy of Sciences, 2003, Volume: 1009 This study was designed to investigate the effect of the endogenous beta-carboline, harmane, on neuropathic pain produced by chronic constriction injury (CCI) of the sciatic nerve. Thermal allodynia evaluations were made preoperatively, postoperatively on the fifteenth day, and after harmane administration. Harmane (1, 2.5, 5, 10, or 20 mg/kg) was administered intraperitoneally for 5 days beginning from postoperative day 15. Treatment with harmane had a profound anti-allodynic effect in a dose-dependent manner. In conclusion, harmane might provide a new approach to treatment of neuropathic pain. Topics: Animals; Carbolines; Cold Temperature; Dose-Response Relationship, Drug; Harmine; Pain; Pain Measurement; Rats; Rats, Wistar; Sciatic Nerve	2003
On the neuropharmacology of harmane and other beta-carbolines. Pharmacology, biochemistry, and behavior, 1981, Volume: 14, Issue:5 Topics: Alkaloids; Animals; Apomorphine; Body Temperature; Carbolines; Central Nervous System; Harmine; Indoles; Male; Pain; Rats; Receptors, Dopamine; Receptors, Drug; Receptors, GABA-A; Receptors, Muscarinic; Receptors, Opioid; Receptors, Serotonin	1981

Article

Year

Effect of harmane on mononeuropathic pain in rats.

Annals of the New York Academy of Sciences, 2003, Volume: 1009

This study was designed to investigate the effect of the endogenous beta-carboline, harmane, on neuropathic pain produced by chronic constriction injury (CCI) of the sciatic nerve. Thermal allodynia evaluations were made preoperatively, postoperatively on the fifteenth day, and after harmane administration. Harmane (1, 2.5, 5, 10, or 20 mg/kg) was administered intraperitoneally for 5 days beginning from postoperative day 15. Treatment with harmane had a profound anti-allodynic effect in a dose-dependent manner. In conclusion, harmane might provide a new approach to treatment of neuropathic pain.

Topics: Animals; Carbolines; Cold Temperature; Dose-Response Relationship, Drug; Harmine; Pain; Pain Measurement; Rats; Rats, Wistar; Sciatic Nerve

2003

On the neuropharmacology of harmane and other beta-carbolines.

Pharmacology, biochemistry, and behavior, 1981, Volume: 14, Issue:5

Topics: Alkaloids; Animals; Apomorphine; Body Temperature; Carbolines; Central Nervous System; Harmine; Indoles; Male; Pain; Rats; Receptors, Dopamine; Receptors, Drug; Receptors, GABA-A; Receptors, Muscarinic; Receptors, Opioid; Receptors, Serotonin

1981