harmaline has been researched along with Tremor in 111 studies
Harmaline: A beta-carboline alkaloid isolated from seeds of PEGANUM.
harmaline : A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7 and has been reduced across the 3,4 bond.
Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cerebellar EDCS suppressed harmaline tremor in rats in a polarity-dependent manner." | 8.31 | Epicranial Direct Current Stimulation Suppresses Harmaline Tremor in Rats. ( Asamoah, B; Boogers, A; Khatoun, A; Mc Laughlin, M, 2023) |
| "The results indicated that ABA (10 μg/rat) can improve harmaline-induced tremor in rats." | 8.12 | Phytohormone abscisic acid elicits positive effects on harmaline-induced cognitive and motor disturbances in a rat model of essential tremor. ( Naderi, R; Shabani, M, 2022) |
| "While harmaline has been used as a pharmacological model of essential tremor (ET) in rodents and pigs, less is known about the effects of this pharmacological treatment in awake-behaving non-human primates." | 8.02 | Considerations Using Harmaline for a Primate Model of Tremor. ( Bello, EM; Blumenfeld, M; Dao, J; Johnson, MD; Krieg, JDS; Wilmerding, LK, 2021) |
| "In a pig model, tremor was induced with harmaline and measured with wireless accelerometers attached to the limbs." | 7.88 | Development of Harmaline-induced Tremor in a Swine Model. ( Chang, SY; Cheng, L; Jang, DP; Kang, SI; Kim, I; Knight, E; Lee, J, 2018) |
| "Harmaline was injected at a dose of 15 mg/kg ip and tremor was measured automatically in force-plate actimeters by an increased averaged power in the frequency band of 9-15 Hz (AP2) and by tremor index (a difference in power between AP2 and averaged power in the frequency band of 0-8 Hz)." | 7.85 | Tremorolytic effect of 5'-chloro-5'-deoxy-(±)-ENBA, a potent and selective adenosine A1 receptor agonist, evaluated in the harmaline-induced model in rats. ( Głowacka, U; Kosmowska, B; Ossowska, K; Wardas, J, 2017) |
| "To study the effect of pretreatment with low doses of vanillin, a flavoring agent used as a food additive, on harmaline-induced tremor in rats." | 7.85 | Low-dose acute vanillin is beneficial against harmaline-induced tremors in rats. ( Abdulrahman, AA; Arshaduddin, M; Faisal, K; Meshref, AA, 2017) |
| " Finally, we demonstrate that loss of NCB5OR in the cerebellum and midbrain exacerbated harmaline-induced tremor activity." | 7.83 | Loss of NCB5OR in the cerebellum disturbs iron pathways, potentiates behavioral abnormalities, and exacerbates harmaline-induced tremor in mice. ( McCarson, KE; Stroh, MA; Swerdlow, RH; Winter, MK; Zhu, H, 2016) |
| "Harmaline-induced tremor is a well-known model of essential tremor in humans." | 7.81 | Apomorphine enhances harmaline-induced tremor in rats. ( Głowacka, U; Kosmowska, B; Ossowska, K; Wardas, J, 2015) |
| "Harmaline induces tremor in animals resembling essential tremor which has been suggested to result from activation of the glutamatergic olivo-cerebellar projection." | 7.80 | Lu AF21934, a positive allosteric modulator of mGlu4 receptors, reduces the harmaline-induced hyperactivity but not tremor in rats. ( Berghauzen-Maciejewska, K; Doller, D; Głowacka, U; Kuter, K; Ossowska, K; Pilc, A; Wardas, J; Zorn, SH, 2014) |
| "The aim of the present study was to examine the influence of a unilateral 6-hydroxydopamine (6-OHDA)-induced partial lesion of both the substantia nigra pars compacta (SNc, A9) and retrorubral field (RRF, A8) on the tremor evoked by harmaline." | 7.78 | 6-OHDA injections into A8-A9 dopaminergic neurons modelling early stages of Parkinson's disease increase the harmaline-induced tremor in rats. ( Berghauzen, K; Kolasiewicz, W; Kuter, K; Nowak, P; Ossowska, K; Schulze, G, 2012) |
| " Thus, we aimed to investigate the therapeutic effects of riluzole on harmaline-induced tremor and ataxia in rat, and determining whether riluzole exerts its effect through modulation of glutamate levels in cerebellum." | 7.78 | Effects of riluzole on harmaline induced tremor and ataxia in rats: biochemical, histological and behavioral studies. ( Abrari, K; Elahdadi Salmani, M; Goudarzi, A; Goudarzi, I; Lashkarbolouki, T; Rahimi Shourmasti, F, 2012) |
| "Abnormal synchronous activation of the glutamatergic olivo-cerebellar pathway has been suggested to be crucial for the harmaline-induced tremor." | 7.77 | Lesion of the cerebellar noradrenergic innervation enhances the harmaline-induced tremor in rats. ( Kolasiewicz, W; Kuter, K; Nowak, P; Ossowska, K; Pastuszka, A, 2011) |
| " The current study aims to investigate the anti-tremogenic and neuroprotective effects of memantine (NMDA receptor antagonist) on the harmaline model of transient action tremor." | 7.77 | The effect of memantine in harmaline-induced tremor and neurodegeneration. ( Akman, O; Ates, N; Erturk, S; Gullu, KM; Iseri, PK; Karson, A; Kokturk, S; Yardýmoglu, M, 2011) |
| " This hypothesis was tested by searching for the expression of the Cx57 transcripts in the mouse cerebellum of the harmaline-tremor model." | 7.76 | Expression of connexin57 in mouse development and in harmaline-tremor model. ( Cicirata, F; Cicirata, V; La Delia, F; Parenti, R; Zappalà, A, 2010) |
| "Harmaline-induced tremor in rodents is a model of essential tremor." | 7.75 | Pharmacological characterization of harmaline-induced tremor activity in mice. ( Foreman, MM; Hanania, T; Malekiani, SA; Olivier, B; Paterson, NE, 2009) |
| "32 mg/kg sc strongly enhances tremor of forelimbs, head and trunk, hypolocomotion, and ataxia induced by harmaline (7." | 7.75 | Role of the metabotropic glutamate receptor subtype 1 in the harmaline-induced tremor in rats. ( Kolasiewicz, W; Kuter, K; Ossowska, K; Wardas, J, 2009) |
| "Effect of zonisamide on harmaline- or oxotreorine-induced tremors, and tacrine-induced tremulous jaw movements (TJMs) was studied." | 7.74 | Effects of zonisamide on experimental tremors in rats. ( Hama, K; Kajimoto, Y; Kondo, T; Miwa, H, 2008) |
| "Excessive olivo-cerebellar burst-firing occurs during harmaline-induced tremor." | 7.72 | Vagus nerve stimulation inhibits harmaline-induced tremor. ( Handforth, A; Krahl, SE; Martin, FC, 2004) |
| "We studied whether vagus nerve stimulation could suppress tremor in the harmaline tremor model in the rat." | 7.71 | Suppression of harmaline-induced tremor in rats by vagus nerve stimulation. ( Handforth, A; Krahl, SE, 2001) |
| "Recent experimental and clinical studies clearly suggest the role of gamma-aminobutyric acid (GABA) in the pathogenesis of tremors." | 7.71 | Baclofen attenuates harmaline induced tremors in rats. ( Al Deeb, S; Al Moutaery, K; Arshaduddin, M; Biary, N; Tariq, M, 2001) |
| "Both harmaline and physostigmine are known to produce whole-body tremors in rodents, yet there is little quantitative information on the differential frequency characteristics of these tremors or on other possible motor effects of these drugs." | 7.71 | Concurrent quantification of tremor and depression of locomotor activity induced in rats by harmaline and physostigmine. ( Fowler, SC; Wang, G, 2001) |
| "Recent studies suggest an association between caffeine consumption and tremor." | 7.71 | Effect of acute caffeine on severity of harmaline induced tremor in rats. ( Al-Deeb, S; Al-Moutaery, K; Arshaduddin, M; Biary, N; Tariq, M, 2002) |
| "A behavioral preparation especially sensitive to low-dose drug effects on fine motor behavior in rats was used to assess the tremorogenic effects of harmaline, an indole alkaloid and beta-carboline derivative." | 7.70 | At low doses, harmaline increases forelimb tremor in the rat. ( Fowler, SC; Stanford, JA, 1998) |
| "The present study was undertaken to investigate the effect of lidocaine on harmaline-induced tremors in the rat." | 7.70 | Effect of lidocaine on harmaline-induced tremors in the rat. ( Al Deeb, S; Al Moutaery, K; Arshaduddin, M; Biary, N; Tariq, M, 2000) |
| "This study reports that corticotropin-releasing factor (CRF) expression within the inferior olivary complex (IOC) of the cat is increased 8 h after administration of the tremor-inducing beta-carboline harmaline." | 7.69 | Corticotropin-releasing factor mRNA increases in the inferior olivary complex during harmaline-induced tremor. ( Cummings, S; Hinds, D; Young, WS, 1994) |
| "Harmaline is known to produce tremors and retard acquisition of the rabbit's nictitating membrane response." | 7.69 | Harmaline-induced tremor and impairment of learning are both blocked by dizocilpine in the rabbit. ( Du, W; Harvey, JA, 1997) |
| "The genetically dystonic rat is insensitive to the tremorogenic effects of harmaline." | 7.68 | Effect of harmaline on cells of the inferior olive in the absence of tremor: differential response of genetically dystonic and harmaline-tolerant rats. ( Lorden, JF; Stratton, SE, 1991) |
| " Harmaline produced tremor has been shown to induce rhythmic activity and increase glucose consumption in the IO." | 7.67 | Inferior olivary neurons: 3-acetylpyridine effects on glucose consumption, axonal transport, electrical activity and harmaline-induced tremor. ( Bernard, JF; Buisseret-Delmas, C; Laplante, S, 1984) |
| " Diazepam has been reported to inhibit both the tremor and mechanism of cerebellar cyclic GMP caused by harmaline by a neurotransmission in the cerebellum." | 7.67 | Ethanol effects on harmaline-induced tremor and increase of cerebellar cyclic GMP. ( Dole, VP; Gentry, RT; Rappaport, MS; Schneider, DR, 1984) |
| "Administration of the beta-carboline alkaloid, harmaline, causes the neurons of the inferior olive to fire synchronously and to act as a pacemaker for the generation of tremor." | 7.67 | Tolerance to the tremorogenic effects of harmaline: evidence for altered olivo-cerebellar function. ( Beales, M; Lorden, JF; Lutes, J; Oltmans, GA, 1988) |
| "Specific beta 1- and beta 2-adrenoceptor antagonists, acebutolol and butoxamine respectively were used to investigate the involvement of blockade of these receptors in the inhibition of harmaline-induced tremors." | 7.67 | Involvement of beta 2-adrenoceptor blockade and 5-hydroxytryptamine mechanism in inhibition of harmaline-induced tremors in rats. ( Paul, V, 1986) |
| "The effects of excitatory amino acids, kainic acid and quisqualic acid, on the tremorine- and harmaline-induced tremor were quantitatively examined in mice using the power spectral analyzing method." | 7.67 | Modification of drug-induced tremor by systemic administration of kainic acid and quisqualic acid in mice. ( Hirate, K; Ishida, M; Shinozaki, H, 1987) |
| "Harmaline produces a tremor which is prevented by diazepam." | 7.66 | Harmaline-induced tremor: the benzodiazepine receptor as a site of action. ( Robertson, HA, 1980) |
| " A tremorogenic dose of harmaline (30 mg/kg intravenously) increased binding by 31%." | 7.66 | Binding of beta-carbolines and caffeine on benzodiazepine receptors: correlations to convulsions and tremor. ( Airaksinen, MM; Saano, V, 1982) |
| "In the Rat under tremorogenic doses of harmaline, Purkinje cells of the vermis of the cerebellar cortex display a regular complex spike activity at 6 to 11 Hz ("harmaline-rhythm")." | 7.66 | [Harmaline tremor: topography of activity in the cerebellar cortex in rats]. ( Bernard, JF, 1983) |
| " Moreover, these benzodiazepine antagonists neither attenuated nor potentiated the tremorigenic actions of another beta-carboline, harmaline." | 7.66 | Blockade of 3-carbomethoxy-beta-carboline induced seizures by diazepam and the benzodiazepine antagonists, Ro 15-1788 and CGS 8216. ( Cain, M; Cook, J; Paul, S; Schweri, M; Skolnick, P, 1982) |
| "The brain structures specifically involved in harmaline-induced tremor have been identified in the Rat by using the 14C-2-deoxyglucose marking Method." | 7.66 | [Harmaline-induced tremor and cerebral activities: labeling with 14C-2-deoxyglucose in the rat]. ( Batini, C; Buisseret-Delmas, C; Conrath-Verrier, M, 1978) |
| "Since there is degeneration of substantia nigra concomitant with that of locus coeruleus (LC) in patients with Parkinson's disease, the study was performed to determine the role of central norepinephrine (NE) on harmaline induced tremor." | 7.66 | Significance of central noradrenergic system on harmaline induced tremor. ( Takaori, S; Tanaka, C; Yamazaki, M, 1979) |
| "Harmaline, an alcaloid of Paganum Armala, induces tremors of central origin and increases cerebellar cGMP without affecting cortical and cerebellar prostaglandin levels." | 7.66 | Inhibition of harmaline induced tremors by 16 (S)-16-methyl PGE2 in different mammalian species: a correlation with central cyclic nucleotides and prostaglandins. ( Berti, F; Fano, M; Folco, GC; Longiave, D; Omini, C, 1978) |
| "The possible involvement of serotoninergic mechanisms in the induction of harmaline generated tremor in the inferior olive has been investigated electrophysiologically in the cat and rat." | 7.65 | The indolaminergic innervation of the inferior olive. 2. Relation to harmaline induced tremor. ( Björklund, A; Sjölund, B; Wiklund, L, 1977) |
| "Effect of 3, 4-dihydroxyphenylserine (DOPS), a norepinephrine precurosr, on harmaline tremor was investigated in mice to elucidate the role of norepinephrine in the genesis of tremor." | 7.65 | [Inhibition of harmaline induced tremor by L-threo-3, 4-dihydroxyphenylserine, an L-norepinephrine precursor]. ( Ikeda, Y; Inagaki, C; Ishikawa, M; Tanaka, C; Yamazaki, M, 1976) |
| "Pramipexole was administered at a low dose of 0." | 5.56 | Pramipexole Reduces zif-268 mRNA Expression in Brain Structures involved in the Generation of Harmaline-Induced Tremor. ( Kosmowska, B; Ossowska, K; Wardas, J, 2020) |
| "Imipramine treatment further decreased harmaline-induced 5HT turnover in the brain stem." | 5.33 | Exacerbation of harmaline-induced tremor by imipramine. ( Al Deeb, S; Al Moutaery, K; Arshaduddin, M; Kadasah, S; Tariq, M, 2005) |
| "Tremor is the second most common neurological adverse effect in patients receiving treatment with SSRIs." | 5.32 | Citalopram, a selective serotonin reuptake inhibitor augments harmaline-induced tremor in rats. ( Al Deeb, S; Al Kadasah, S; Al Moutaery, K; Arshaduddin, M; Biary, N; Tariq, M, 2004) |
| "Harmaline was used in this study because its tremorgenic action is mediated at the level of IO; octanol was found to be a potent antagonist of harmaline-induced tremor." | 5.28 | The effectiveness of different isomers of octanol as blockers of harmaline-induced tremor. ( Krosser, BI; Llinás, RR; Sinton, CM; Walton, KD, 1989) |
| "Cerebellar EDCS suppressed harmaline tremor in rats in a polarity-dependent manner." | 4.31 | Epicranial Direct Current Stimulation Suppresses Harmaline Tremor in Rats. ( Asamoah, B; Boogers, A; Khatoun, A; Mc Laughlin, M, 2023) |
| " Only non-impairing doses were used to evaluate for anti-tremor efficacy in the harmaline model, which was assessed in wildtype and α6 subunit knockout littermates." | 4.31 | Search for Novel Therapies for Essential Tremor Based on Positive Modulation of α6-Containing GABA ( Ernst, M; Handforth, A; Singh, RP; Treven, M, 2023) |
| "The results indicated that ABA (10 μg/rat) can improve harmaline-induced tremor in rats." | 4.12 | Phytohormone abscisic acid elicits positive effects on harmaline-induced cognitive and motor disturbances in a rat model of essential tremor. ( Naderi, R; Shabani, M, 2022) |
| "While harmaline has been used as a pharmacological model of essential tremor (ET) in rodents and pigs, less is known about the effects of this pharmacological treatment in awake-behaving non-human primates." | 4.02 | Considerations Using Harmaline for a Primate Model of Tremor. ( Bello, EM; Blumenfeld, M; Dao, J; Johnson, MD; Krieg, JDS; Wilmerding, LK, 2021) |
| "Using this system, we were able to characterize both the microtremors in netrin-G2 KO mice and low-dose harmaline-induced tremors which, to date, had been difficult to detect." | 4.02 | Objective detection of microtremors in netrin-G2 knockout mice. ( Ajima, A; Itohara, S; Yaguchi, K; Yoshida, T, 2021) |
| "In a pig model, tremor was induced with harmaline and measured with wireless accelerometers attached to the limbs." | 3.88 | Development of Harmaline-induced Tremor in a Swine Model. ( Chang, SY; Cheng, L; Jang, DP; Kang, SI; Kim, I; Knight, E; Lee, J, 2018) |
| "Harmaline was injected at a dose of 15 mg/kg ip and tremor was measured automatically in force-plate actimeters by an increased averaged power in the frequency band of 9-15 Hz (AP2) and by tremor index (a difference in power between AP2 and averaged power in the frequency band of 0-8 Hz)." | 3.85 | Tremorolytic effect of 5'-chloro-5'-deoxy-(±)-ENBA, a potent and selective adenosine A1 receptor agonist, evaluated in the harmaline-induced model in rats. ( Głowacka, U; Kosmowska, B; Ossowska, K; Wardas, J, 2017) |
| "To study the effect of pretreatment with low doses of vanillin, a flavoring agent used as a food additive, on harmaline-induced tremor in rats." | 3.85 | Low-dose acute vanillin is beneficial against harmaline-induced tremors in rats. ( Abdulrahman, AA; Arshaduddin, M; Faisal, K; Meshref, AA, 2017) |
| " Finally, we demonstrate that loss of NCB5OR in the cerebellum and midbrain exacerbated harmaline-induced tremor activity." | 3.83 | Loss of NCB5OR in the cerebellum disturbs iron pathways, potentiates behavioral abnormalities, and exacerbates harmaline-induced tremor in mice. ( McCarson, KE; Stroh, MA; Swerdlow, RH; Winter, MK; Zhu, H, 2016) |
| "Hybrid tremor analysis of harmaline-induced and genetic tremor in mice revealed that two authentic tremor frequencies for each type of tremor were conserved and showed an opposite dependence on CaV3." | 3.81 | Heterogeneity of tremor mechanisms assessed by tremor-related cortical potential in mice. ( Chang, KY; Choi, JH; Kim, D; Kim, S; Kim, Y; Lee, C; Paek, SH; Park, YG, 2015) |
| "Harmaline-induced tremor is a well-known model of essential tremor in humans." | 3.81 | Apomorphine enhances harmaline-induced tremor in rats. ( Głowacka, U; Kosmowska, B; Ossowska, K; Wardas, J, 2015) |
| "Harmaline induces tremor in animals resembling essential tremor which has been suggested to result from activation of the glutamatergic olivo-cerebellar projection." | 3.80 | Lu AF21934, a positive allosteric modulator of mGlu4 receptors, reduces the harmaline-induced hyperactivity but not tremor in rats. ( Berghauzen-Maciejewska, K; Doller, D; Głowacka, U; Kuter, K; Ossowska, K; Pilc, A; Wardas, J; Zorn, SH, 2014) |
| "The aim of the present study was to examine the influence of a partial lesion of both the substantia nigra pars compacta (SNC) and retrorubral field (RRF) on the glutamatergic transmission in the cerebellum and tremor induced by harmaline in rats." | 3.79 | A partial lesion of the substantia nigra pars compacta and retrorubral field decreases the harmaline-induced glutamate release in the rat cerebellum. ( Berghauzen-Maciejewska, K; Górska, A; Gołembiowska, K; Kamińska, K; Ossowska, K, 2013) |
| "The aim of the present study was to examine the influence of a unilateral 6-hydroxydopamine (6-OHDA)-induced partial lesion of both the substantia nigra pars compacta (SNc, A9) and retrorubral field (RRF, A8) on the tremor evoked by harmaline." | 3.78 | 6-OHDA injections into A8-A9 dopaminergic neurons modelling early stages of Parkinson's disease increase the harmaline-induced tremor in rats. ( Berghauzen, K; Kolasiewicz, W; Kuter, K; Nowak, P; Ossowska, K; Schulze, G, 2012) |
| " Thus, we aimed to investigate the therapeutic effects of riluzole on harmaline-induced tremor and ataxia in rat, and determining whether riluzole exerts its effect through modulation of glutamate levels in cerebellum." | 3.78 | Effects of riluzole on harmaline induced tremor and ataxia in rats: biochemical, histological and behavioral studies. ( Abrari, K; Elahdadi Salmani, M; Goudarzi, A; Goudarzi, I; Lashkarbolouki, T; Rahimi Shourmasti, F, 2012) |
| "Abnormal synchronous activation of the glutamatergic olivo-cerebellar pathway has been suggested to be crucial for the harmaline-induced tremor." | 3.77 | Lesion of the cerebellar noradrenergic innervation enhances the harmaline-induced tremor in rats. ( Kolasiewicz, W; Kuter, K; Nowak, P; Ossowska, K; Pastuszka, A, 2011) |
| " The current study aims to investigate the anti-tremogenic and neuroprotective effects of memantine (NMDA receptor antagonist) on the harmaline model of transient action tremor." | 3.77 | The effect of memantine in harmaline-induced tremor and neurodegeneration. ( Akman, O; Ates, N; Erturk, S; Gullu, KM; Iseri, PK; Karson, A; Kokturk, S; Yardýmoglu, M, 2011) |
| " This hypothesis was tested by searching for the expression of the Cx57 transcripts in the mouse cerebellum of the harmaline-tremor model." | 3.76 | Expression of connexin57 in mouse development and in harmaline-tremor model. ( Cicirata, F; Cicirata, V; La Delia, F; Parenti, R; Zappalà, A, 2010) |
| "Harmaline-induced tremor in rodents is a model of essential tremor." | 3.75 | Pharmacological characterization of harmaline-induced tremor activity in mice. ( Foreman, MM; Hanania, T; Malekiani, SA; Olivier, B; Paterson, NE, 2009) |
| "32 mg/kg sc strongly enhances tremor of forelimbs, head and trunk, hypolocomotion, and ataxia induced by harmaline (7." | 3.75 | Role of the metabotropic glutamate receptor subtype 1 in the harmaline-induced tremor in rats. ( Kolasiewicz, W; Kuter, K; Ossowska, K; Wardas, J, 2009) |
| "Effect of zonisamide on harmaline- or oxotreorine-induced tremors, and tacrine-induced tremulous jaw movements (TJMs) was studied." | 3.74 | Effects of zonisamide on experimental tremors in rats. ( Hama, K; Kajimoto, Y; Kondo, T; Miwa, H, 2008) |
| " As a positive control for postural instability, wild type mice were injected with harmaline, a tremorigenic agent, and the average areas of the 95% confidence ellipse, which measures 95% of the CoP trajectory values recorded in a single trial, were measured." | 3.74 | Quantitative measurement of postural sway in mouse models of human neurodegenerative disease. ( Colton, CA; Dawson, HN; Dodd, M; Ho, V; Hutchinson, D; Schmitt, D; Zumwalt, AC, 2007) |
| "The rodent model of harmaline-induced tremor has been widely used for experimental analysis of tremor." | 3.73 | A species-specific difference in the effects of harmaline on the rodent olivocerebellar system. ( Kihira, T; Kondo, T; Kubo, T; Miwa, H; Suzuki, A, 2006) |
| "Excessive olivo-cerebellar burst-firing occurs during harmaline-induced tremor." | 3.72 | Vagus nerve stimulation inhibits harmaline-induced tremor. ( Handforth, A; Krahl, SE; Martin, FC, 2004) |
| " Harmaline, a beta-carboline derivative thought to induce tremor by facilitating rhythmogenesis in the IO, was injected systemically into WT and KO mice." | 3.71 | Rhythmicity without synchrony in the electrically uncoupled inferior olive. ( Connors, BW; Deans, MR; Long, MA; Paul, DL, 2002) |
| "We studied whether vagus nerve stimulation could suppress tremor in the harmaline tremor model in the rat." | 3.71 | Suppression of harmaline-induced tremor in rats by vagus nerve stimulation. ( Handforth, A; Krahl, SE, 2001) |
| "Recent experimental and clinical studies clearly suggest the role of gamma-aminobutyric acid (GABA) in the pathogenesis of tremors." | 3.71 | Baclofen attenuates harmaline induced tremors in rats. ( Al Deeb, S; Al Moutaery, K; Arshaduddin, M; Biary, N; Tariq, M, 2001) |
| "Both harmaline and physostigmine are known to produce whole-body tremors in rodents, yet there is little quantitative information on the differential frequency characteristics of these tremors or on other possible motor effects of these drugs." | 3.71 | Concurrent quantification of tremor and depression of locomotor activity induced in rats by harmaline and physostigmine. ( Fowler, SC; Wang, G, 2001) |
| "Recent studies suggest an association between caffeine consumption and tremor." | 3.71 | Effect of acute caffeine on severity of harmaline induced tremor in rats. ( Al-Deeb, S; Al-Moutaery, K; Arshaduddin, M; Biary, N; Tariq, M, 2002) |
| "A behavioral preparation especially sensitive to low-dose drug effects on fine motor behavior in rats was used to assess the tremorogenic effects of harmaline, an indole alkaloid and beta-carboline derivative." | 3.70 | At low doses, harmaline increases forelimb tremor in the rat. ( Fowler, SC; Stanford, JA, 1998) |
| "The present study was undertaken to investigate the effect of lidocaine on harmaline-induced tremors in the rat." | 3.70 | Effect of lidocaine on harmaline-induced tremors in the rat. ( Al Deeb, S; Al Moutaery, K; Arshaduddin, M; Biary, N; Tariq, M, 2000) |
| " Moreover, the tremor elicited by harmaline was also correlated with the extent of the IOC lesion." | 3.69 | Effect of administration of 3-acetylpyridine followed by niacinamide injection on survival, extent of the inferior olivary complex lesion, and response to harmaline in the young rat. ( Caston, J; Jones, N; Le Marec, N; Stelz, T, 1994) |
| "This study reports that corticotropin-releasing factor (CRF) expression within the inferior olivary complex (IOC) of the cat is increased 8 h after administration of the tremor-inducing beta-carboline harmaline." | 3.69 | Corticotropin-releasing factor mRNA increases in the inferior olivary complex during harmaline-induced tremor. ( Cummings, S; Hinds, D; Young, WS, 1994) |
| " The synchronous activation of inferior olive neurons by the drug harmaline is known to produce tremorogenic activity in rats via increased stimulation of the olivocerebellar system." | 3.69 | An experimental model for the non-invasive trans-synaptic induction of nitric oxide synthase in Purkinje cells of the rat cerebellum. ( Beitz, AJ; Saxon, DW, 1996) |
| "Harmaline is known to produce tremors and retard acquisition of the rabbit's nictitating membrane response." | 3.69 | Harmaline-induced tremor and impairment of learning are both blocked by dizocilpine in the rabbit. ( Du, W; Harvey, JA, 1997) |
| "We studied the effect of various kinds of beta-adrenergic blockers on oxotremorine-, harmaline- and thyrotropin-releasing hormone (TRH)-induced tremors in mice." | 3.68 | Effects of beta-adrenergic blockers on drug-induced tremors. ( Fukuda, T; Iwata, S; Nomoto, M, 1993) |
| "The genetically dystonic rat is insensitive to the tremorogenic effects of harmaline." | 3.68 | Effect of harmaline on cells of the inferior olive in the absence of tremor: differential response of genetically dystonic and harmaline-tolerant rats. ( Lorden, JF; Stratton, SE, 1991) |
| " Harmaline produced tremor has been shown to induce rhythmic activity and increase glucose consumption in the IO." | 3.67 | Inferior olivary neurons: 3-acetylpyridine effects on glucose consumption, axonal transport, electrical activity and harmaline-induced tremor. ( Bernard, JF; Buisseret-Delmas, C; Laplante, S, 1984) |
| " Diazepam has been reported to inhibit both the tremor and mechanism of cerebellar cyclic GMP caused by harmaline by a neurotransmission in the cerebellum." | 3.67 | Ethanol effects on harmaline-induced tremor and increase of cerebellar cyclic GMP. ( Dole, VP; Gentry, RT; Rappaport, MS; Schneider, DR, 1984) |
| "Administration of the beta-carboline alkaloid, harmaline, causes the neurons of the inferior olive to fire synchronously and to act as a pacemaker for the generation of tremor." | 3.67 | Tolerance to the tremorogenic effects of harmaline: evidence for altered olivo-cerebellar function. ( Beales, M; Lorden, JF; Lutes, J; Oltmans, GA, 1988) |
| "Specific beta 1- and beta 2-adrenoceptor antagonists, acebutolol and butoxamine respectively were used to investigate the involvement of blockade of these receptors in the inhibition of harmaline-induced tremors." | 3.67 | Involvement of beta 2-adrenoceptor blockade and 5-hydroxytryptamine mechanism in inhibition of harmaline-induced tremors in rats. ( Paul, V, 1986) |
| " Phenotypically normal rats showed tremor in response to harmaline, a drug that acts on the inferior olive to produce bursting in the climbing fiber pathway." | 3.67 | Decreased cerebellar 3',5'-cyclic guanosine monophosphate levels and insensitivity to harmaline in the genetically dystonic rat (dt). ( Beales, M; Lorden, JF; Lutes, J; McKeon, TW; Oltmans, GA, 1985) |
| " As regards behavioural effects, tremor induced by quipazine was present from the first postnatal day and was antagonized by methysergide, but not by p-chlorophenylalanine (PCPA) or pretreatment with 5,7-dihydroxytryptamine (5,7-DHT)." | 3.67 | Drug-induced activation of the inferior olivary nucleus in young rabbits. Differential effects of harmaline and quipazine. ( Barragan, LA; Delhaye-Bouchaud, N; Laget, P, 1985) |
| "The effects of excitatory amino acids, kainic acid and quisqualic acid, on the tremorine- and harmaline-induced tremor were quantitatively examined in mice using the power spectral analyzing method." | 3.67 | Modification of drug-induced tremor by systemic administration of kainic acid and quisqualic acid in mice. ( Hirate, K; Ishida, M; Shinozaki, H, 1987) |
| "The effects of diazepam, dantrolene and atropine on drug-induced tremors were investigated in mice from the point of view of the tremor frequency." | 3.67 | Further studies on quantification of drug-induced tremor in mice: effects of antitremorgenic agents on tremor frequency. ( Hirate, K; Ishida, M; Shinozaki, H, 1985) |
| "Harmaline produces a tremor which is prevented by diazepam." | 3.66 | Harmaline-induced tremor: the benzodiazepine receptor as a site of action. ( Robertson, HA, 1980) |
| " A tremorogenic dose of harmaline (30 mg/kg intravenously) increased binding by 31%." | 3.66 | Binding of beta-carbolines and caffeine on benzodiazepine receptors: correlations to convulsions and tremor. ( Airaksinen, MM; Saano, V, 1982) |
| "In the Rat under tremorogenic doses of harmaline, Purkinje cells of the vermis of the cerebellar cortex display a regular complex spike activity at 6 to 11 Hz ("harmaline-rhythm")." | 3.66 | [Harmaline tremor: topography of activity in the cerebellar cortex in rats]. ( Bernard, JF, 1983) |
| " Moreover, these benzodiazepine antagonists neither attenuated nor potentiated the tremorigenic actions of another beta-carboline, harmaline." | 3.66 | Blockade of 3-carbomethoxy-beta-carboline induced seizures by diazepam and the benzodiazepine antagonists, Ro 15-1788 and CGS 8216. ( Cain, M; Cook, J; Paul, S; Schweri, M; Skolnick, P, 1982) |
| "The brain structures specifically involved in harmaline-induced tremor have been identified in the Rat by using the 14C-2-deoxyglucose marking Method." | 3.66 | [Harmaline-induced tremor and cerebral activities: labeling with 14C-2-deoxyglucose in the rat]. ( Batini, C; Buisseret-Delmas, C; Conrath-Verrier, M, 1978) |
| "Since there is degeneration of substantia nigra concomitant with that of locus coeruleus (LC) in patients with Parkinson's disease, the study was performed to determine the role of central norepinephrine (NE) on harmaline induced tremor." | 3.66 | Significance of central noradrenergic system on harmaline induced tremor. ( Takaori, S; Tanaka, C; Yamazaki, M, 1979) |
| "Harmaline, an alcaloid of Paganum Armala, induces tremors of central origin and increases cerebellar cGMP without affecting cortical and cerebellar prostaglandin levels." | 3.66 | Inhibition of harmaline induced tremors by 16 (S)-16-methyl PGE2 in different mammalian species: a correlation with central cyclic nucleotides and prostaglandins. ( Berti, F; Fano, M; Folco, GC; Longiave, D; Omini, C, 1978) |
| "Cyclic GMP levels were dose-dependently increased by excitatory drugs such as picrotoxin, pentetrazol, oxotremorine and harmaline in mouse cerebellum and medial forebrain (parts of the cortex, hippocampus, hypothalamus, thalamus, striatum and midbrain) in vivo." | 3.65 | Effects of stimulatory and depressant drugs on cyclic guanosine 3',5'-monophosphate and adenosine 3',5'-monophosphate levels in mouse brain. ( Dinnedahl, V; Gumulka, SW; Opmeer, FA; Schönhöfer, PS, 1976) |
| " Over a 24 hour period, the following symptoms could be observed: akathisia, circling, akinesia, choreoathetoid and dystonic movements, oro-facial dyskinesias and postural tremor with or without harmaline." | 3.65 | Haloperidol-induced dyskinesias in the monkey. ( Bédard, P; Delean, J; Lafleur, J; Larochelle, L, 1977) |
| "The possible involvement of serotoninergic mechanisms in the induction of harmaline generated tremor in the inferior olive has been investigated electrophysiologically in the cat and rat." | 3.65 | The indolaminergic innervation of the inferior olive. 2. Relation to harmaline induced tremor. ( Björklund, A; Sjölund, B; Wiklund, L, 1977) |
| "Effect of 3, 4-dihydroxyphenylserine (DOPS), a norepinephrine precurosr, on harmaline tremor was investigated in mice to elucidate the role of norepinephrine in the genesis of tremor." | 3.65 | [Inhibition of harmaline induced tremor by L-threo-3, 4-dihydroxyphenylserine, an L-norepinephrine precursor]. ( Ikeda, Y; Inagaki, C; Ishikawa, M; Tanaka, C; Yamazaki, M, 1976) |
| "Hindlimb tremor was produced in chronic cats by intracaudate microinjection of the monoamine oxidase (MAO) inhibitors tranylcypromine and harmaline throughout a range of doses (150-385 mug)." | 3.65 | Contrasting local effects of MAO inhibitors on caudate tremor activities. ( Baker, WW; Malseed, RT; Zivanovic, D, 1975) |
| "Animal models of tremor have been widely used in experimental neurology, because they are an indispensable requirement for understanding the pathophysiology of human tremor disorders and the development of new therapeutic agents." | 2.40 | Animal models of tremor. ( Deuschl, G; Sievers, J; Wilms, H, 1999) |
| "We postulate that palatal myoclonus after infarction of the brainstem or cerebellum, or both, is the manifestation of denervation supersensitivity secondary to lesions involving the dentatorubroolivary system." | 2.36 | Palatal myoclonus and denervation supersensitivity in the central nervous system. ( Ajax, ET; Matsuo, F, 1979) |
| "Harmaline-induced tremor is an easily provoked model for the development of new therapies for essential tremor (ET)." | 1.91 | Mapping Pharmacologically Evoked Neurovascular Activation and Its Suppression in a Rat Model of Tremor Using Functional Ultrasound: A Feasibility Study. ( Alizad, A; Chang, SY; Fatemi, M; Lee, J; Nayak, R; Sotoudehnia, S, 2023) |
| "Pramipexole was administered at a low dose of 0." | 1.56 | Pramipexole Reduces zif-268 mRNA Expression in Brain Structures involved in the Generation of Harmaline-Induced Tremor. ( Kosmowska, B; Ossowska, K; Wardas, J, 2020) |
| "Tremor is currently ranked as the most common movement disorder." | 1.56 | Purkinje cell misfiring generates high-amplitude action tremors that are corrected by cerebellar deep brain stimulation. ( Brown, AM; Lin, T; Sillitoe, RV; van der Heijden, ME; White, JJ; Zhou, J, 2020) |
| "Imipramine treatment further decreased harmaline-induced 5HT turnover in the brain stem." | 1.33 | Exacerbation of harmaline-induced tremor by imipramine. ( Al Deeb, S; Al Moutaery, K; Arshaduddin, M; Kadasah, S; Tariq, M, 2005) |
| "Harmaline treatment had no later effects on the climbing fiber EPSC kinetics and I/V relation in Purkinje cells (P15-36)." | 1.32 | A change in the pattern of activity affects the developmental regression of the Purkinje cell polyinnervation by climbing fibers in the rat cerebellum. ( Andjus, PR; Carulli, D; Cesa, R; Strata, P; Zhu, L, 2003) |
| "Tremor is the second most common neurological adverse effect in patients receiving treatment with SSRIs." | 1.32 | Citalopram, a selective serotonin reuptake inhibitor augments harmaline-induced tremor in rats. ( Al Deeb, S; Al Kadasah, S; Al Moutaery, K; Arshaduddin, M; Biary, N; Tariq, M, 2004) |
| " Mitochondrial swelling occurs in cerebellar stellate and basket cells within 30 minutes of dosing and persists for more than 12 hours without leading to cell death." | 1.30 | The effects of the tremorgenic mycotoxin penitrem A on the rat cerebellum. ( Cavanagh, JB; Holton, JL; Mantle, PG; Naik, JT; Nolan, CC; Ray, DE, 1998) |
| "Harmaline was used in this study because its tremorgenic action is mediated at the level of IO; octanol was found to be a potent antagonist of harmaline-induced tremor." | 1.28 | The effectiveness of different isomers of octanol as blockers of harmaline-induced tremor. ( Krosser, BI; Llinás, RR; Sinton, CM; Walton, KD, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 51 (45.95) | 18.7374 |
| 1990's | 14 (12.61) | 18.2507 |
| 2000's | 20 (18.02) | 29.6817 |
| 2010's | 14 (12.61) | 24.3611 |
| 2020's | 12 (10.81) | 2.80 |
| Authors | Studies |
|---|---|
| Bello, EM | 1 |
| Blumenfeld, M | 1 |
| Dao, J | 1 |
| Krieg, JDS | 1 |
| Wilmerding, LK | 1 |
| Johnson, MD | 1 |
| Shabani, M | 1 |
| Naderi, R | 1 |
| Lee, J | 4 |
| Kim, J | 1 |
| Cortez, J | 1 |
| Chang, SY | 3 |
| Khatoun, A | 1 |
| Asamoah, B | 1 |
| Boogers, A | 1 |
| Mc Laughlin, M | 1 |
| Kuo, SH | 1 |
| Kosmowska, B | 4 |
| Paleczna, M | 1 |
| Biała, D | 1 |
| Kadłuczka, J | 1 |
| Wardas, J | 6 |
| Witkin, JM | 1 |
| Cook, JM | 1 |
| Sharmin, D | 1 |
| Marcinkowska, M | 1 |
| Kuter, KZ | 1 |
| Handforth, A | 4 |
| Kosoyan, HP | 1 |
| Kadam, PA | 1 |
| Singh, RP | 2 |
| Nayak, R | 1 |
| Sotoudehnia, S | 1 |
| Fatemi, M | 1 |
| Alizad, A | 1 |
| Treven, M | 1 |
| Ernst, M | 1 |
| Ossowska, K | 8 |
| Brown, AM | 1 |
| White, JJ | 1 |
| van der Heijden, ME | 1 |
| Zhou, J | 1 |
| Lin, T | 1 |
| Sillitoe, RV | 1 |
| Ajima, A | 1 |
| Yoshida, T | 1 |
| Yaguchi, K | 1 |
| Itohara, S | 1 |
| Głowacka, U | 3 |
| Kim, I | 1 |
| Knight, E | 1 |
| Cheng, L | 1 |
| Kang, SI | 1 |
| Jang, DP | 1 |
| Gołembiowska, K | 1 |
| Berghauzen-Maciejewska, K | 2 |
| Górska, A | 1 |
| Kamińska, K | 1 |
| Kuter, K | 4 |
| Pilc, A | 1 |
| Zorn, SH | 1 |
| Doller, D | 1 |
| Park, YG | 2 |
| Choi, JH | 1 |
| Lee, C | 1 |
| Kim, S | 1 |
| Kim, Y | 1 |
| Chang, KY | 1 |
| Paek, SH | 1 |
| Kim, D | 2 |
| Stroh, MA | 1 |
| Winter, MK | 1 |
| Swerdlow, RH | 1 |
| McCarson, KE | 1 |
| Zhu, H | 1 |
| Abdulrahman, AA | 1 |
| Faisal, K | 1 |
| Meshref, AA | 1 |
| Arshaduddin, M | 7 |
| Lamarre, Y | 3 |
| Dumont, M | 2 |
| Joffroy, AJ | 2 |
| Paterson, NE | 1 |
| Malekiani, SA | 1 |
| Foreman, MM | 1 |
| Olivier, B | 1 |
| Hanania, T | 1 |
| Kolasiewicz, W | 3 |
| Park, HY | 1 |
| Lee, CJ | 1 |
| Choi, S | 1 |
| Jo, S | 1 |
| Choi, H | 1 |
| Kim, YH | 1 |
| Shin, HS | 1 |
| Llinas, RR | 2 |
| Zappalà, A | 1 |
| Parenti, R | 1 |
| La Delia, F | 1 |
| Cicirata, V | 1 |
| Cicirata, F | 1 |
| Nowak, P | 2 |
| Pastuszka, A | 1 |
| Iseri, PK | 1 |
| Karson, A | 1 |
| Gullu, KM | 1 |
| Akman, O | 1 |
| Kokturk, S | 1 |
| Yardýmoglu, M | 1 |
| Erturk, S | 1 |
| Ates, N | 1 |
| Berghauzen, K | 1 |
| Schulze, G | 1 |
| Rahimi Shourmasti, F | 1 |
| Goudarzi, I | 1 |
| Lashkarbolouki, T | 1 |
| Abrari, K | 1 |
| Elahdadi Salmani, M | 1 |
| Goudarzi, A | 1 |
| Tariq, M | 6 |
| Biary, N | 5 |
| Al Moutaery, K | 5 |
| Al Deeb, S | 5 |
| Long, MA | 1 |
| Deans, MR | 1 |
| Paul, DL | 1 |
| Connors, BW | 1 |
| AHMED, A | 1 |
| TAYLOR, NR | 1 |
| Mehta, H | 1 |
| Saravanan, KS | 1 |
| Mohanakumar, KP | 1 |
| Andjus, PR | 1 |
| Zhu, L | 1 |
| Cesa, R | 1 |
| Carulli, D | 1 |
| Strata, P | 1 |
| Krahl, SE | 2 |
| Martin, FC | 1 |
| McMahon, A | 1 |
| Fowler, SC | 3 |
| Perney, TM | 1 |
| Akemann, W | 1 |
| Knöpfel, T | 1 |
| Joho, RH | 1 |
| Al Kadasah, S | 1 |
| Kadasah, S | 1 |
| Miwa, H | 4 |
| Kubo, T | 1 |
| Suzuki, A | 1 |
| Kihira, T | 1 |
| Kondo, T | 2 |
| Hama, K | 1 |
| Kajimoto, Y | 1 |
| Hutchinson, D | 1 |
| Ho, V | 1 |
| Dodd, M | 1 |
| Dawson, HN | 1 |
| Zumwalt, AC | 1 |
| Schmitt, D | 1 |
| Colton, CA | 1 |
| Fagni, L | 1 |
| Weiss, M | 4 |
| Pellet, J | 2 |
| Hugon, M | 1 |
| Bernard, JF | 6 |
| Buisseret-Delmas, C | 7 |
| Laplante, S | 2 |
| Robertson, HA | 1 |
| Knowles, WD | 1 |
| Phillips, MI | 1 |
| Saano, V | 1 |
| Airaksinen, MM | 1 |
| Rappaport, MS | 1 |
| Gentry, RT | 1 |
| Schneider, DR | 1 |
| Dole, VP | 1 |
| Shinozaki, H | 5 |
| Hirate, K | 4 |
| Ishida, M | 3 |
| Compoint, C | 1 |
| Horcholle-Bossavit, G | 3 |
| Gemba, H | 1 |
| Sasaki, K | 1 |
| Yoneda, Y | 1 |
| Hashimoto, S | 1 |
| Mizuno, N | 1 |
| Batini, C | 6 |
| Schweri, M | 1 |
| Cain, M | 1 |
| Cook, J | 1 |
| Paul, S | 1 |
| Skolnick, P | 1 |
| Conrath-Verrier, M | 4 |
| Milner, TE | 1 |
| Cadoret, G | 1 |
| Lessard, L | 1 |
| Smith, AM | 1 |
| Jones, N | 2 |
| Le Marec, N | 1 |
| Stelz, T | 2 |
| Caston, J | 2 |
| Glick, SD | 1 |
| Kuehne, ME | 1 |
| Raucci, J | 1 |
| Wilson, TE | 1 |
| Larson, D | 1 |
| Keller, RW | 1 |
| Carlson, JN | 1 |
| Cummings, S | 1 |
| Hinds, D | 1 |
| Young, WS | 1 |
| Cross, AJ | 1 |
| Misra, A | 1 |
| Sandilands, A | 1 |
| Taylor, MJ | 1 |
| Green, AR | 1 |
| Iwata, S | 1 |
| Nomoto, M | 1 |
| Fukuda, T | 1 |
| Saxon, DW | 1 |
| Beitz, AJ | 1 |
| Du, W | 1 |
| Harvey, JA | 1 |
| Stanford, JA | 1 |
| Cavanagh, JB | 1 |
| Holton, JL | 1 |
| Nolan, CC | 1 |
| Ray, DE | 1 |
| Naik, JT | 1 |
| Mantle, PG | 1 |
| Welsh, JP | 1 |
| Wilms, H | 1 |
| Sievers, J | 1 |
| Deuschl, G | 1 |
| Nishi, K | 1 |
| Fuwa, T | 1 |
| Mizuno, Y | 1 |
| Wang, G | 1 |
| Al-Deeb, S | 1 |
| Al-Moutaery, K | 1 |
| Poirier, LJ | 1 |
| Sourkes, TL | 1 |
| Matsuo, F | 1 |
| Ajax, ET | 1 |
| Brailowsky, S | 1 |
| Walter, S | 1 |
| Vuillon-Cacciuttolo, G | 1 |
| Serbanescu, T | 1 |
| Simantov, R | 1 |
| Snyder, SH | 1 |
| Oster-Granite, ML | 1 |
| Guidotti, A | 2 |
| Biggio, G | 1 |
| Costa, E | 2 |
| Opmeer, FA | 1 |
| Gumulka, SW | 1 |
| Dinnedahl, V | 1 |
| Schönhöfer, PS | 1 |
| Mao, CC | 1 |
| Bédard, P | 1 |
| Delean, J | 1 |
| Lafleur, J | 1 |
| Larochelle, L | 1 |
| Yamazaki, M | 2 |
| Tanaka, C | 2 |
| Takaori, S | 1 |
| Headley, PM | 1 |
| Lodge, D | 1 |
| Woodhams, P | 1 |
| Rodd, R | 1 |
| Balázs, R | 1 |
| Berti, F | 1 |
| Fano, M | 1 |
| Folco, GC | 1 |
| Longiave, D | 1 |
| Omini, C | 1 |
| De Montigny, C | 1 |
| Grou, F | 1 |
| Lund, JP | 1 |
| Goldstein, M | 1 |
| Anagnoste, B | 1 |
| Battista, AF | 1 |
| Ogawa, M | 1 |
| Sjölund, B | 1 |
| Björklund, A | 1 |
| Wiklund, L | 1 |
| Ikeda, Y | 1 |
| Ishikawa, M | 1 |
| Inagaki, C | 1 |
| Baker, WW | 1 |
| Zivanovic, D | 1 |
| Malseed, RT | 1 |
| Stratton, SE | 1 |
| Lorden, JF | 3 |
| Sinton, CM | 1 |
| Krosser, BI | 1 |
| Walton, KD | 1 |
| Lutes, J | 2 |
| Beales, M | 2 |
| Oltmans, GA | 2 |
| Paul, V | 1 |
| Longo, VG | 1 |
| Massotti, M | 1 |
| McKeon, TW | 1 |
| Barragan, LA | 1 |
| Delhaye-Bouchaud, N | 1 |
| Laget, P | 1 |
| Zetler, G | 1 |
| Back, G | 1 |
| Iven, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessment of Routine Use of Critical View of Safety in Laparoscopic Cholecystectomy, Prospective Cohort Study[NCT03696823] | 50 participants (Anticipated) | Interventional | 2018-10-01 | Not yet recruiting | |||
| Effect of Alcohol on Physiologic and Pathologic Tremors[NCT00001925] | Phase 2 | 23 participants | Interventional | 1999-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for harmaline and Tremor
| Article | Year |
|---|---|
[Parkinsonian tremor and the action of harmaline: experimental facts and hypothetical mechanisms].
Topics: Animals; Central Nervous System Stimulants; Cerebellum; Diencephalon; Efferent Pathways; Haplorhini; | 1973 |
Rodent models of tremor.
Topics: Animals; Brain; Central Nervous System Stimulants; Disease Models, Animal; Harmaline; Humans; Mice; | 2007 |
Animal models of tremor.
Topics: Animals; Central Nervous System Diseases; Disease Models, Animal; Harmaline; Humans; Mammals; Specie | 1999 |
Monkeys with nigrostriatal lesions: tremor induced by harmaline and other drugs.
Topics: Alkaloids; Animals; Corpus Striatum; Haplorhini; Harmaline; Methyltyrosines; Phenothiazines; Substan | 1976 |
Palatal myoclonus and denervation supersensitivity in the central nervous system.
Topics: Adult; Aged; Brain Stem; Cerebellum; Cerebral Infarction; Female; Harmaline; Humans; Hypertrophy; Ma | 1979 |
Evidence for involvement of GABA in the action of benzodiazepines: studies on rat cerebellum.
Topics: Aminobutyrates; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebellum; Cyclic GMP; gamma-Aminobu | 1975 |
Monkeys with nigrostriatal lesions effects of monoaminergic drugs.
Topics: Amino Acids; Animals; Antiparkinson Agents; Apomorphine; Biogenic Amines; Carboxy-Lyases; Catechol O | 1976 |
Tremorgenic mechanisms in primates.
Topics: Animals; Cerebellum; Cerebral Cortex; Harmaline; Motor Cortex; Primates; Tegmentum Mesencephali; Tha | 1975 |
Effect of tremorigenic agents on the cerebellum: a review of biochemical and electrophysiological data.
Topics: Alkaloids; Animals; Cats; Cerebellar Nuclei; Cerebellum; Cyclic GMP; Diazepam; Dopamine; Electroence | 1985 |
102 other studies available for harmaline and Tremor
| Article | Year |
|---|---|
Considerations Using Harmaline for a Primate Model of Tremor.
Topics: Animals; Essential Tremor; Harmaline; Humans; Macaca mulatta; Swine; Tremor | 2021 |
Phytohormone abscisic acid elicits positive effects on harmaline-induced cognitive and motor disturbances in a rat model of essential tremor.
Topics: Abscisic Acid; Animals; Cognition; Essential Tremor; Harmaline; Male; Mammals; Neuroprotective Agent | 2022 |
Thalamo-cortical network is associated with harmaline-induced tremor in rodent model.
Topics: Animals; Deep Brain Stimulation; Essential Tremor; Harmaline; Motor Cortex; Propranolol; Rats; Roden | 2022 |
Epicranial Direct Current Stimulation Suppresses Harmaline Tremor in Rats.
Topics: Animals; Cerebellum; Essential Tremor; Harmaline; Rats; Rats, Sprague-Dawley; Tremor | 2023 |
GABA
Topics: Cerebellum; Essential Tremor; Harmaline; Humans; Receptors, GABA-A; Tremor | 2023 |
GABA-A Alpha 2/3 but Not Alpha 1 Receptor Subunit Ligand Inhibits Harmaline and Pimozide-Induced Tremor in Rats.
Topics: Animals; Essential Tremor; gamma-Aminobutyric Acid; Harmaline; Ligands; Pimozide; Rats; Rats, Spragu | 2023 |
Alcohol and Ganaxolone Suppress Tremor via Extra-Synaptic GABA
Topics: Animals; Essential Tremor; Ethanol; gamma-Aminobutyric Acid; Harmaline; Humans; Mice; Receptors, GAB | 2023 |
Mapping Pharmacologically Evoked Neurovascular Activation and Its Suppression in a Rat Model of Tremor Using Functional Ultrasound: A Feasibility Study.
Topics: Animals; Essential Tremor; Feasibility Studies; Harmaline; Propranolol; Rats; Tremor | 2023 |
Search for Novel Therapies for Essential Tremor Based on Positive Modulation of α6-Containing GABA
Topics: Animals; Essential Tremor; Flumazenil; gamma-Aminobutyric Acid; Harmaline; Humans; Ketamine; Mice; M | 2023 |
Pramipexole Reduces zif-268 mRNA Expression in Brain Structures involved in the Generation of Harmaline-Induced Tremor.
Topics: Animals; Antiparkinson Agents; Brain; Central Nervous System Stimulants; Early Growth Response Prote | 2020 |
Purkinje cell misfiring generates high-amplitude action tremors that are corrected by cerebellar deep brain stimulation.
Topics: Animals; Cerebellum; Deep Brain Stimulation; Female; gamma-Aminobutyric Acid; Harmaline; Male; Mice; | 2020 |
Objective detection of microtremors in netrin-G2 knockout mice.
Topics: Animals; Essential Tremor; Harmaline; Humans; Mice; Mice, Knockout; Netrins; Tremor | 2021 |
Tremorolytic effect of 5'-chloro-5'-deoxy-(±)-ENBA, a potent and selective adenosine A1 receptor agonist, evaluated in the harmaline-induced model in rats.
Topics: Adenosine A1 Receptor Agonists; Animals; Brain; Deoxyadenosines; Disease Models, Animal; Dose-Respon | 2017 |
Development of Harmaline-induced Tremor in a Swine Model.
Topics: Accelerometry; Animals; Disease Models, Animal; Harmaline; Sus scrofa; Tremor; Wireless Technology | 2018 |
A partial lesion of the substantia nigra pars compacta and retrorubral field decreases the harmaline-induced glutamate release in the rat cerebellum.
Topics: Animals; Cerebellum; Dopamine; Dopaminergic Neurons; Glutamic Acid; Harmaline; Male; Rats; Rats, Wis | 2013 |
Lu AF21934, a positive allosteric modulator of mGlu4 receptors, reduces the harmaline-induced hyperactivity but not tremor in rats.
Topics: Anilides; Animals; Central Nervous System Stimulants; Cerebellum; Cyclohexanecarboxylic Acids; Harma | 2014 |
Heterogeneity of tremor mechanisms assessed by tremor-related cortical potential in mice.
Topics: Action Potentials; Animals; Cerebral Cortex; Disease Models, Animal; Harmaline; Mice; Tremor | 2015 |
Apomorphine enhances harmaline-induced tremor in rats.
Topics: Animals; Apomorphine; Central Nervous System Stimulants; Dopamine Agonists; Drug Synergism; Harmalin | 2015 |
Loss of NCB5OR in the cerebellum disturbs iron pathways, potentiates behavioral abnormalities, and exacerbates harmaline-induced tremor in mice.
Topics: Animals; Behavior, Animal; Cerebellum; Cytochrome-B(5) Reductase; Harmaline; Homeostasis; Iron; Mese | 2016 |
Low-dose acute vanillin is beneficial against harmaline-induced tremors in rats.
Topics: Animals; Antioxidants; Benzaldehydes; Central Nervous System Stimulants; Disease Models, Animal; Har | 2017 |
Pharmacological characterization of harmaline-induced tremor activity in mice.
Topics: Affect; Animals; Anticonvulsants; Baclofen; Behavior, Animal; Benzazepines; Carbolines; Chlordiazepo | 2009 |
Role of the metabotropic glutamate receptor subtype 1 in the harmaline-induced tremor in rats.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Exploratory Be | 2009 |
Ca(V)3.1 is a tremor rhythm pacemaker in the inferior olive.
Topics: Animals; Calcium Channels, T-Type; Cell Line; Disease Models, Animal; Harmaline; Humans; Male; Mice; | 2010 |
Expression of connexin57 in mouse development and in harmaline-tremor model.
Topics: Age Factors; Animals; Animals, Newborn; Central Nervous System; Central Nervous System Stimulants; C | 2010 |
Lesion of the cerebellar noradrenergic innervation enhances the harmaline-induced tremor in rats.
Topics: Adrenergic Agents; Animals; Brain Chemistry; Central Nervous System Stimulants; Cerebellum; Chromato | 2011 |
The effect of memantine in harmaline-induced tremor and neurodegeneration.
Topics: Animals; Cerebellum; Ethanol; Harmaline; Male; Memantine; Nerve Degeneration; Neuroprotective Agents | 2011 |
6-OHDA injections into A8-A9 dopaminergic neurons modelling early stages of Parkinson's disease increase the harmaline-induced tremor in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Central Nervous System Stimulants; Cereb | 2012 |
Effects of riluzole on harmaline induced tremor and ataxia in rats: biochemical, histological and behavioral studies.
Topics: Animals; Ataxia; Behavior, Animal; Cerebellum; Glutamates; Harmaline; Ion Channels; Male; Neuroprote | 2012 |
2-deoxy-D-glucose attenuates harmaline induced tremors in rats.
Topics: Animals; Antimetabolites; Deoxyglucose; Dose-Response Relationship, Drug; Electromyography; Female; | 2002 |
Rhythmicity without synchrony in the electrically uncoupled inferior olive.
Topics: Action Potentials; Animals; Connexins; Culture Techniques; Gap Junction delta-2 Protein; Gap Junctio | 2002 |
The analysis of drug-induced tremor in mice.
Topics: Animals; Harmaline; Lysergic Acid Diethylamide; Mice; Tremor; Tremorine | 1959 |
Serotonin synthesis inhibition in olivo-cerebellar system attenuates harmaline-induced tremor in Swiss albino mice.
Topics: Animals; Behavior, Animal; Brain Chemistry; Cerebellum; Chromatography, High Pressure Liquid; Dopami | 2003 |
A change in the pattern of activity affects the developmental regression of the Purkinje cell polyinnervation by climbing fibers in the rat cerebellum.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Calbindins; Carrier Proteins; Cell Death; Centra | 2003 |
Vagus nerve stimulation inhibits harmaline-induced tremor.
Topics: Animals; Electric Stimulation Therapy; Harmaline; Male; Rats; Rats, Long-Evans; Tremor; Vagus Nerve | 2004 |
Allele-dependent changes of olivocerebellar circuit properties in the absence of the voltage-gated potassium channels Kv3.1 and Kv3.3.
Topics: Action Potentials; Alleles; Animals; Blotting, Western; Central Nervous System Stimulants; Cerebellu | 2004 |
Citalopram, a selective serotonin reuptake inhibitor augments harmaline-induced tremor in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Chemistry; Central Nervous System Stimulants; | 2004 |
Exacerbation of harmaline-induced tremor by imipramine.
Topics: Animals; Drug Synergism; Harmaline; Imipramine; Male; Rats; Rats, Sprague-Dawley; Tremor | 2005 |
A species-specific difference in the effects of harmaline on the rodent olivocerebellar system.
Topics: Animals; Cerebellum; Data Interpretation, Statistical; Harmaline; Immunohistochemistry; Male; Mice; | 2006 |
Effects of zonisamide on experimental tremors in rats.
Topics: Animals; Anticonvulsants; Central Nervous System Stimulants; Cholinesterase Inhibitors; Harmaline; I | 2008 |
Quantitative measurement of postural sway in mouse models of human neurodegenerative disease.
Topics: Age Factors; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Behavior, Animal; Biomechani | 2007 |
The possible mechanisms of the high pressure-induced motor disturbances in the cat.
Topics: Animals; Cats; Cerebellum; Electromyography; Female; Harmaline; Male; Peripheral Nerves; Posture; Pr | 1982 |
Inferior olivary neurons: 3-acetylpyridine effects on glucose consumption, axonal transport, electrical activity and harmaline-induced tremor.
Topics: Alkaloids; Animals; Autoradiography; Axonal Transport; Deoxyglucose; Glucose; Harmaline; Olivary Nuc | 1984 |
Harmaline-induced tremor: the benzodiazepine receptor as a site of action.
Topics: Alkaloids; Animals; Binding, Competitive; Brain; Flunitrazepam; Harmaline; Male; Mice; Mice, Inbred | 1980 |
Neurophysiological and behavioral maturation of cerebellar function studied with tremorogenic drugs.
Topics: Action Potentials; Aging; Alkaloids; Animals; Animals, Newborn; Cerebellum; Harmaline; Nerve Fibers; | 1980 |
Binding of beta-carbolines and caffeine on benzodiazepine receptors: correlations to convulsions and tremor.
Topics: Animals; Brain; Caffeine; Carbolines; Flunitrazepam; Harmaline; Harmine; Indoles; Male; Rats; Rats, | 1982 |
Ethanol effects on harmaline-induced tremor and increase of cerebellar cyclic GMP.
Topics: Alkaloids; Animals; Cerebellum; Cyclic GMP; Diazepam; Dose-Response Relationship, Drug; Ethanol; Har | 1984 |
[Harmaline tremor: topography of activity in the cerebellar cortex in rats].
Topics: Animals; Cerebellar Cortex; Harmaline; Rats; Tremor | 1983 |
[A quantitative analyzing method for drug-induced tremor].
Topics: Animals; Ethology; Harmaline; Magnetics; Mice; Monitoring, Physiologic; Motor Activity; Oxotremorine | 1984 |
Harmaline induced tremor. III. A combined simple units, horseradish peroxidase, and 2-deoxyglucose study of the olivocerebellar system in the rat.
Topics: Alkaloids; Animals; Brain Mapping; Glucose; Harmaline; Neural Pathways; Olivary Nucleus; Purkinje Ce | 1984 |
Quantitative analysis of drug-induced tremor in mice.
Topics: Alkaloids; Animals; Harmaline; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Oxotremorine; Spe | 1984 |
Harmaline-induced rhythm in the lateral reticular nucleus.
Topics: Action Potentials; Alkaloids; Animals; Autoradiography; Cats; Harmaline; Lidocaine; Medulla Oblongat | 1983 |
Tremor in the monkey with a cerebellar lesion.
Topics: Animals; Bemegride; Cerebellum; Haplorhini; Harmaline; Ketamine; Macaca; Movement; Tremor | 1980 |
[Harmaline tremor: activity of the interposito-rubral system and of the bulbo-ponto-reticular formation].
Topics: Alkaloids; Animals; Carbon Radioisotopes; Cats; Deoxyglucose; Efferent Pathways; Harmaline; Medulla | 1980 |
Blockade of 3-carbomethoxy-beta-carboline induced seizures by diazepam and the benzodiazepine antagonists, Ro 15-1788 and CGS 8216.
Topics: Animals; Benzodiazepinones; Carbolines; Convulsants; Diazepam; Dose-Response Relationship, Drug; Flu | 1982 |
Rhythmic activity of spinal interneurons in harmaline-treated cats. A model for olivo-cerebellar influence at the spinal level.
Topics: Action Potentials; Alkaloids; Animals; Cats; Cerebellum; Harmaline; Interneurons; Olivary Nucleus; S | 1982 |
Harmaline-induced tremor. I. Regional metabolic activity as revealed by [14C]2-deoxyglucose in cat.
Topics: Alkaloids; Animals; Brain; Carbon Radioisotopes; Cats; Caudate Nucleus; Cerebellar Cortex; Cerebellu | 1981 |
Harmaline-induced tremor. II. Unit activity correlation in the interposito-rubral and oculomotor systems of cat.
Topics: Alkaloids; Brain Stem; Electric Stimulation; Eye Movements; Harmaline; Neurons; Oculomotor Muscles; | 1981 |
EMG analysis of harmaline-induced tremor in normal and three strains of mutant mice with Purkinje cell degeneration and the role of the inferior olive.
Topics: Animals; Cerebellum; Electromyography; Harmaline; Injections, Intraperitoneal; Mice; Mice, Mutant St | 1995 |
Effect of administration of 3-acetylpyridine followed by niacinamide injection on survival, extent of the inferior olivary complex lesion, and response to harmaline in the young rat.
Topics: Animals; Brain; Harmaline; Injections, Intraperitoneal; Niacinamide; Olivary Nucleus; Pyridines; Rat | 1994 |
Effects of iboga alkaloids on morphine and cocaine self-administration in rats: relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens and striatum.
Topics: Alkaloids; Animals; Cocaine; Corpus Striatum; Dopamine; Female; Harmaline; Ibogaine; Microdialysis; | 1994 |
Corticotropin-releasing factor mRNA increases in the inferior olivary complex during harmaline-induced tremor.
Topics: Animals; Autoradiography; Cats; Corticotropin-Releasing Hormone; Gene Expression; Harmaline; In Situ | 1994 |
Effect of chlormethiazole, dizocilpine and pentobarbital on harmaline-induced increase of cerebellar cyclic GMP and tremor.
Topics: Animals; Cerebellum; Chlormethiazole; Cyclic GMP; Dizocilpine Maleate; Harmaline; Male; Mice; Mice, | 1993 |
Effects of beta-adrenergic blockers on drug-induced tremors.
Topics: Adrenergic beta-Antagonists; Animals; Fourier Analysis; Harmaline; Male; Mice; Mice, Inbred Strains; | 1993 |
Effects of lesion of the inferior olivary complex in learning of the equilibrium behavior in the young rat during ontogenesis. I. Total lesion of the inferior olive by 3-acetylpyridine.
Topics: Aging; Animals; Animals, Newborn; Harmaline; Learning; Motor Activity; Nerve Degeneration; Olivary N | 1995 |
An experimental model for the non-invasive trans-synaptic induction of nitric oxide synthase in Purkinje cells of the rat cerebellum.
Topics: Amino Acid Sequence; Animals; Calbindins; Cerebellum; Enzyme Induction; Harmaline; Immunohistochemis | 1996 |
Harmaline-induced tremor and impairment of learning are both blocked by dizocilpine in the rabbit.
Topics: Animals; Conditioning, Classical; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory | 1997 |
At low doses, harmaline increases forelimb tremor in the rat.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drinking; Drug Administration Schedule; | 1998 |
The effects of the tremorgenic mycotoxin penitrem A on the rat cerebellum.
Topics: Animals; Brain; Capillary Permeability; Cerebellum; Cerebrovascular Circulation; Dendrites; Electrom | 1998 |
Systemic harmaline blocks associative and motor learning by the actions of the inferior olive.
Topics: Animals; Association Learning; Conditioning, Classical; Female; Harmaline; Learning; Male; Memory; M | 1998 |
Effect of lidocaine on harmaline-induced tremors in the rat.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Electromyography; Harmaline; Lidocaine; Rats; Ra | 2000 |
Differential expression of c-fos following administration of two tremorgenic agents: harmaline and oxotremorine.
Topics: Animals; Brain; Cell Count; Dose-Response Relationship, Drug; Harmaline; Male; Neural Pathways; Neur | 2000 |
Suppression of harmaline-induced tremor in rats by vagus nerve stimulation.
Topics: Animals; Central Nervous System Stimulants; Disease Models, Animal; Electric Stimulation; Harmaline; | 2001 |
Baclofen attenuates harmaline induced tremors in rats.
Topics: Animals; Baclofen; Brain; Dose-Response Relationship, Drug; Drug Interactions; Electromyography; Ess | 2001 |
Concurrent quantification of tremor and depression of locomotor activity induced in rats by harmaline and physostigmine.
Topics: Animals; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Tolerance; Harmaline; Mal | 2001 |
Effect of acute caffeine on severity of harmaline induced tremor in rats.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Electromyography; Harm | 2002 |
[Harmaline-induced tremor and cerebral activities: labeling with 14C-2-deoxyglucose in the rat].
Topics: Alkaloids; Animals; Brain; Carbon Radioisotopes; Cerebral Cortex; Deoxyglucose; Frontal Lobe; Harmal | 1978 |
[Indole alkaloids induction of tremors: effect on photosensible epilepsy in Papiopapio].
Topics: Alkaloids; Animals; Cerebral Cortex; Dihydroergotoxine; Haplorhini; Harmaline; Ibogaine; Papio; Phot | 1975 |
Harmaline-induced tremor in the rat: abolition by 3-acetylpyridine destruction of cerebellar climbing fibers.
Topics: Alkaloids; Animals; Cerebellar Cortex; Harmaline; Male; Niacinamide; Nicotinic Acids; Oxotremorine; | 1976 |
3-Acetylpyridine: a tool to inhibit the tremor and the increase of cGMP content in cerebellar cortex elicited by harmaline.
Topics: Alkaloids; Animals; Brain Chemistry; Cerebellar Cortex; Cyclic GMP; Glutamates; Harmaline; Male; Oxo | 1975 |
Effects of stimulatory and depressant drugs on cyclic guanosine 3',5'-monophosphate and adenosine 3',5'-monophosphate levels in mouse brain.
Topics: Animals; Atropine; Brain; Brain Chemistry; Convulsants; Cyclic AMP; Cyclic GMP; Diazepam; Drug Inter | 1976 |
Haloperidol-induced dyskinesias in the monkey.
Topics: Animals; Brain; Dyskinesia, Drug-Induced; Haloperidol; Haplorhini; Harmaline; Macaca; Tremor | 1977 |
[Effects of juxtafastigial stimulation on the rhythmic activity of Purkinje cells in harmaline-treated rats].
Topics: Alkaloids; Animals; Evoked Potentials; Harmaline; Olivary Nucleus; Purkinje Cells; Rats; Reaction Ti | 1979 |
Significance of central noradrenergic system on harmaline induced tremor.
Topics: Alkaloids; Animals; Corpus Striatum; Droxidopa; Electric Stimulation; Harmaline; Hydroxydopamines; I | 1979 |
Could harmaline generate tremor by affecting 5HT release? [proceedings].
Topics: Alkaloids; Animals; Brain; Harmaline; Rats; Serotonin; Tremor | 1979 |
Olivo-cerebellar activity during harmaline-induced tremor.A 2-[14C]deoxyglucose study.
Topics: Alkaloids; Animals; Cats; Cerebellum; Deoxy Sugars; Deoxyglucose; Electric Stimulation; Harmaline; T | 1979 |
[Influence of the olivo-cerebello-bulbar system on the motor neurons of the lumbar spinal cord in the cat after administration of harmaline].
Topics: Alkaloids; Animals; Cats; Cerebellum; Harmaline; Medulla Oblongata; Motor Neurons; Olivary Nucleus; | 1978 |
Age-dependent susceptibility of inferior olive neurones to 3-acetylpyridine in the rat.
Topics: Afferent Pathways; Age Factors; Animals; Cerebellum; Harmaline; Lethal Dose 50; Neurons; Olivary Nuc | 1978 |
Inhibition of harmaline induced tremors by 16 (S)-16-methyl PGE2 in different mammalian species: a correlation with central cyclic nucleotides and prostaglandins.
Topics: Alkaloids; Animals; Brain; Cats; Cerebellum; Cerebral Cortex; Harmaline; Male; Nucleotides, Cyclic; | 1978 |
Central mechanisms of tremor in some feline and primate models.
Topics: Animals; Brain; Cats; Cerebellum; Disease Models, Animal; Electromyography; Haplorhini; Harmaline; M | 1975 |
The indolaminergic innervation of the inferior olive. 2. Relation to harmaline induced tremor.
Topics: 5,6-Dihydroxytryptamine; Afferent Pathways; Alkaloids; Animals; Cats; Cerebellum; Female; Harmaline; | 1977 |
[Inhibition of harmaline induced tremor by L-threo-3, 4-dihydroxyphenylserine, an L-norepinephrine precursor].
Topics: Alkaloids; Animals; Brain Chemistry; Droxidopa; Drug Synergism; Harmaline; Isomerism; Locomotion; Ma | 1976 |
Contrasting local effects of MAO inhibitors on caudate tremor activities.
Topics: Alkaloids; Animals; Cats; Caudate Nucleus; Harmaline; Hemicholinium 3; Male; Physostigmine; Tranylcy | 1975 |
Effect of harmaline on cells of the inferior olive in the absence of tremor: differential response of genetically dystonic and harmaline-tolerant rats.
Topics: Animals; Dystonia; Electric Stimulation; Harmaline; Monoamine Oxidase; Olivary Nucleus; Rats; Rats, | 1991 |
The effectiveness of different isomers of octanol as blockers of harmaline-induced tremor.
Topics: Alkaloids; Animals; Calcium Channels; Harmaline; Isomerism; Male; Octanols; Olivary Nucleus; Rats; R | 1989 |
Tolerance to the tremorogenic effects of harmaline: evidence for altered olivo-cerebellar function.
Topics: Alkaloids; Animals; Cerebellum; Cyclic GMP; Diazepam; Drug Tolerance; Harmaline; Morphine; Olivary N | 1988 |
Involvement of beta 2-adrenoceptor blockade and 5-hydroxytryptamine mechanism in inhibition of harmaline-induced tremors in rats.
Topics: 5-Hydroxytryptophan; Acebutolol; Adrenergic beta-Antagonists; Alkaloids; Animals; Butoxamine; Female | 1986 |
Decreased cerebellar 3',5'-cyclic guanosine monophosphate levels and insensitivity to harmaline in the genetically dystonic rat (dt).
Topics: Alkaloids; Animals; Behavior, Animal; Cerebellum; Cyclic GMP; Drug Resistance; Dystonia; Harmaline; | 1985 |
Drug-induced activation of the inferior olivary nucleus in young rabbits. Differential effects of harmaline and quipazine.
Topics: 5,7-Dihydroxytryptamine; Alkaloids; Animals; Dose-Response Relationship, Drug; Electrophysiology; Ex | 1985 |
Modification of drug-induced tremor by systemic administration of kainic acid and quisqualic acid in mice.
Topics: Animals; Dose-Response Relationship, Drug; Harmaline; Kainic Acid; Mice; Oxadiazoles; Quisqualic Aci | 1987 |
Depression of drug-induced tremor by a new isoxazol derivative in mice.
Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Harmaline; Isoxazoles; Male; Mice; Mice, Inbred | 1986 |
Further studies on quantification of drug-induced tremor in mice: effects of antitremorgenic agents on tremor frequency.
Topics: Animals; Benzodiazepines; Dantrolene; Dose-Response Relationship, Drug; Harmaline; Male; Mice; Time | 1985 |
PHARMACOKINETICS In the rat of the hallucinogenic alkaloids harmine and harmaline.
Topics: Alkaloids; Animals; Blood Proteins; Chromatography, Thin Layer; Erythrocytes; Half-Life; Harmaline; | 1974 |