harmaline has been researched along with Idiopathic Parkinson Disease in 7 studies
Harmaline: A beta-carboline alkaloid isolated from seeds of PEGANUM.
harmaline : A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7 and has been reduced across the 3,4 bond.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the present study was to examine the influence of a unilateral 6-hydroxydopamine (6-OHDA)-induced partial lesion of both the substantia nigra pars compacta (SNc, A9) and retrorubral field (RRF, A8) on the tremor evoked by harmaline." | 7.78 | 6-OHDA injections into A8-A9 dopaminergic neurons modelling early stages of Parkinson's disease increase the harmaline-induced tremor in rats. ( Berghauzen, K; Kolasiewicz, W; Kuter, K; Nowak, P; Ossowska, K; Schulze, G, 2012) |
| "The aim of the present study was to examine the influence of a unilateral 6-hydroxydopamine (6-OHDA)-induced partial lesion of both the substantia nigra pars compacta (SNc, A9) and retrorubral field (RRF, A8) on the tremor evoked by harmaline." | 3.78 | 6-OHDA injections into A8-A9 dopaminergic neurons modelling early stages of Parkinson's disease increase the harmaline-induced tremor in rats. ( Berghauzen, K; Kolasiewicz, W; Kuter, K; Nowak, P; Ossowska, K; Schulze, G, 2012) |
| " Two lines of evidence strongly suggest that the bursting pallidal activities are a consequence of the interruption of the nigrostriatal dopaminergic pathway: (1) the percentage of bursting pallidal neurons is proportional to the amount of degeneration in the pars compacta of the ipsilateral substantia nigra; (2) chronic administration of dopamine antagonists, haloperidol and reserpine, reproduces in intact monkeys the bursting activities observed in lesioned animals." | 1.26 | Effects of interruption of the nigrostriatal pathway and of dopaminergic agents on the spontaneous activity of globus pallidus neurons in the awake monkey. ( Filion, M, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Banerjee, R | 1 |
| Kumar, M | 1 |
| Gaurav, I | 1 |
| Thakur, S | 1 |
| Thakur, A | 1 |
| Singh, K | 1 |
| Karak, S | 1 |
| Das, R | 1 |
| Chhabra, M | 1 |
| Wang, YH | 1 |
| Samoylenko, V | 1 |
| Tekwani, BL | 1 |
| Khan, IA | 1 |
| Miller, LS | 1 |
| Chaurasiya, ND | 1 |
| Rahman, MM | 1 |
| Tripathi, LM | 1 |
| Khan, SI | 1 |
| Joshi, VC | 1 |
| Wigger, FT | 1 |
| Muhammad, I | 1 |
| Kolasiewicz, W | 1 |
| Kuter, K | 1 |
| Berghauzen, K | 1 |
| Nowak, P | 1 |
| Schulze, G | 1 |
| Ossowska, K | 1 |
| Cobuzzi, RJ | 1 |
| Neafsey, EJ | 1 |
| Collins, MA | 1 |
| Filion, M | 1 |
| Hassler, R | 1 |
| Wagner, A | 1 |
| Lamarre, Y | 1 |
| Joffroy, AJ | 1 |
| Dumont, M | 1 |
| De Montigny, C | 1 |
| Grou, F | 1 |
| Lund, JP | 1 |
1 review available for harmaline and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Locomotor activity and speed of movements in relation to monoamine-acting drugs.
Topics: Animals; Atropine; Basal Ganglia; Cats; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Harmalin | 1975 |
6 other studies available for harmaline and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
In-silico Prediction of the Beta-carboline Alkaloids Harmine and Harmaline as Potent Drug Candidates for the Treatment of Parkinson's disease.
Topics: Alkaloids; Carbolines; Harmaline; Harmine; Humans; Molecular Docking Simulation; Neurodegenerative D | 2021 |
Composition, standardization and chemical profiling of Banisteriopsis caapi, a plant for the treatment of neurodegenerative disorders relevant to Parkinson's disease.
Topics: Alkaloids; Animals; Banisteriopsis; Beverages; Biflavonoids; Catechin; Ethnopharmacology; Harmaline; | 2010 |
6-OHDA injections into A8-A9 dopaminergic neurons modelling early stages of Parkinson's disease increase the harmaline-induced tremor in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Central Nervous System Stimulants; Cereb | 2012 |
Differential cytotoxicities of N-methyl-beta-carbolinium analogues of MPP+ in PC12 cells: insights into potential neurotoxicants in Parkinson's disease.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cations; Cell Death; Culture Media; Energy Metabolism; Harmali | 1994 |
Effects of interruption of the nigrostriatal pathway and of dopaminergic agents on the spontaneous activity of globus pallidus neurons in the awake monkey.
Topics: Animals; Apomorphine; Corpus Striatum; Evoked Potentials; Globus Pallidus; Haloperidol; Haplorhini; | 1979 |
Central mechanisms of tremor in some feline and primate models.
Topics: Animals; Brain; Cats; Cerebellum; Disease Models, Animal; Electromyography; Haplorhini; Harmaline; M | 1975 |