harmaline has been researched along with Dystonia in 4 studies
Harmaline: A beta-carboline alkaloid isolated from seeds of PEGANUM.
harmaline : A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7 and has been reduced across the 3,4 bond.
Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The genetically dystonic rat is insensitive to the tremorogenic effects of harmaline." | 7.68 | Effect of harmaline on cells of the inferior olive in the absence of tremor: differential response of genetically dystonic and harmaline-tolerant rats. ( Lorden, JF; Stratton, SE, 1991) |
| "The genetically dystonic rat is insensitive to the tremorogenic effects of harmaline." | 3.68 | Effect of harmaline on cells of the inferior olive in the absence of tremor: differential response of genetically dystonic and harmaline-tolerant rats. ( Lorden, JF; Stratton, SE, 1991) |
| " Phenotypically normal rats showed tremor in response to harmaline, a drug that acts on the inferior olive to produce bursting in the climbing fiber pathway." | 3.67 | Decreased cerebellar 3',5'-cyclic guanosine monophosphate levels and insensitivity to harmaline in the genetically dystonic rat (dt). ( Beales, M; Lorden, JF; Lutes, J; McKeon, TW; Oltmans, GA, 1985) |
| "When harmaline was administered systemically to activate the olivo-cerebellar system, in normal rats, increased firing rate and bursting patterns of activity were seen." | 1.28 | Abnormal cerebellar output in rats with an inherited movement disorder. ( Ervin, J; Lorden, JF; Lutes, J; Michela, VL, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lorden, JF | 4 |
| Lutes, J | 2 |
| Michela, VL | 1 |
| Ervin, J | 1 |
| Stratton, SE | 2 |
| Oltmans, GA | 2 |
| McKeon, TW | 1 |
| Beales, M | 1 |
| Mays, LE | 1 |
4 other studies available for harmaline and Dystonia
| Article | Year |
|---|---|
Abnormal cerebellar output in rats with an inherited movement disorder.
Topics: Animals; Cell Count; Cerebellar Nuclei; Dystonia; Electrophysiology; Female; Harmaline; Male; Phenot | 1992 |
Effect of harmaline on cells of the inferior olive in the absence of tremor: differential response of genetically dystonic and harmaline-tolerant rats.
Topics: Animals; Dystonia; Electric Stimulation; Harmaline; Monoamine Oxidase; Olivary Nucleus; Rats; Rats, | 1991 |
Decreased cerebellar 3',5'-cyclic guanosine monophosphate levels and insensitivity to harmaline in the genetically dystonic rat (dt).
Topics: Alkaloids; Animals; Behavior, Animal; Cerebellum; Cyclic GMP; Drug Resistance; Dystonia; Harmaline; | 1985 |
Spontaneous and harmaline-stimulated Purkinje cell activity in rats with a genetic movement disorder.
Topics: Action Potentials; Alkaloids; Animals; Dystonia; Harmaline; Purkinje Cells; Rats; Rats, Mutant Strai | 1988 |