harmaline has been researched along with Depressive Disorder in 2 studies
Harmaline: A beta-carboline alkaloid isolated from seeds of PEGANUM.
harmaline : A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7 and has been reduced across the 3,4 bond.
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Studies in animals have shown anxiolytic and antidepressive effects of ayahuasca, harmine, and harmaline, and experimental studies in humans and mental health assessments of experienced ayahuasca consumers also suggest that ayahuasca is associated with reductions in anxiety and depressive symptoms." | 4.93 | Antidepressive and anxiolytic effects of ayahuasca: a systematic literature review of animal and human studies. ( Crippa, JA; Dos Santos, RG; Hallak, JE; Osório, FL, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dos Santos, RG | 1 |
| Osório, FL | 1 |
| Crippa, JA | 1 |
| Hallak, JE | 1 |
| Santos, RG | 1 |
| Landeira-Fernandez, J | 1 |
| Strassman, RJ | 1 |
| Motta, V | 1 |
| Cruz, AP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Open-Label Dose-Ranging Study of Oral SM-001 in Healthy Adults[NCT05894902] | Phase 1 | 12 participants (Anticipated) | Interventional | 2023-10-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for harmaline and Depressive Disorder
| Article | Year |
|---|---|
Antidepressive and anxiolytic effects of ayahuasca: a systematic literature review of animal and human studies.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Banisteriopsis; Depressive Disorder; H | 2016 |
1 trial available for harmaline and Depressive Disorder
| Article | Year |
|---|---|
Effects of ayahuasca on psychometric measures of anxiety, panic-like and hopelessness in Santo Daime members.
Topics: Adult; Anxiety; Banisteriopsis; Beverages; Brazil; Depressive Disorder; Double-Blind Method; Female; | 2007 |