harmaline has been researched along with Anxiety in 9 studies
Harmaline: A beta-carboline alkaloid isolated from seeds of PEGANUM.
harmaline : A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7 and has been reduced across the 3,4 bond.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Harmaline (HA) is a beta-carboline commonly known to provoke motor alterations through activation of cells in the inferior olive." | 5.33 | Effects of harmaline on anxiety-related behavior in mice. ( Chapillon, P; Hilber, P, 2005) |
| " Studies in animals have shown anxiolytic and antidepressive effects of ayahuasca, harmine, and harmaline, and experimental studies in humans and mental health assessments of experienced ayahuasca consumers also suggest that ayahuasca is associated with reductions in anxiety and depressive symptoms." | 4.93 | Antidepressive and anxiolytic effects of ayahuasca: a systematic literature review of animal and human studies. ( Crippa, JA; Dos Santos, RG; Hallak, JE; Osório, FL, 2016) |
| ") injection of cinanserin (5-HT2 receptor antagonist) on harmaline-induced responses on depression- and anxiety-like behaviors in the ARS mice." | 4.02 | Synergistic antidepressant- and anxiolytic-like effects of harmaline along with cinanserin in acute restraint stress-treated mice. ( Ahmadi, H; Ebrahimi-Ghiri, M; Khakpai, F; Mosaffa, S; Zarrindast, MR, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Mosaffa, S | 1 |
| Ahmadi, H | 1 |
| Khakpai, F | 1 |
| Ebrahimi-Ghiri, M | 2 |
| Zarrindast, MR | 2 |
| Dahmardeh, N | 1 |
| Asadi-Shekaari, M | 1 |
| Arjmand, S | 1 |
| Kalantaripour, T | 1 |
| Basiri, M | 1 |
| Shabani, M | 4 |
| Nasehi, M | 1 |
| Mohammadi, F | 1 |
| Abedini Esfahlani, M | 1 |
| Vaziri, Z | 2 |
| Abbassian, H | 2 |
| Sheibani, V | 2 |
| Haghani, M | 1 |
| Nazeri, M | 1 |
| Aghaei, I | 2 |
| Dos Santos, RG | 1 |
| Osório, FL | 1 |
| Crippa, JA | 1 |
| Hallak, JE | 1 |
| Esmaeili, P | 1 |
| Tahamtan, M | 1 |
| Whalley, BJ | 1 |
| Hilber, P | 1 |
| Chapillon, P | 1 |
| Santos, RG | 1 |
| Landeira-Fernandez, J | 1 |
| Strassman, RJ | 1 |
| Motta, V | 1 |
| Cruz, AP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Open-Label Dose-Ranging Study of Oral SM-001 in Healthy Adults[NCT05894902] | Phase 1 | 12 participants (Anticipated) | Interventional | 2023-10-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for harmaline and Anxiety
| Article | Year |
|---|---|
Antidepressive and anxiolytic effects of ayahuasca: a systematic literature review of animal and human studies.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Banisteriopsis; Depressive Disorder; H | 2016 |
1 trial available for harmaline and Anxiety
| Article | Year |
|---|---|
Effects of ayahuasca on psychometric measures of anxiety, panic-like and hopelessness in Santo Daime members.
Topics: Adult; Anxiety; Banisteriopsis; Beverages; Brazil; Depressive Disorder; Double-Blind Method; Female; | 2007 |
7 other studies available for harmaline and Anxiety
| Article | Year |
|---|---|
Synergistic antidepressant- and anxiolytic-like effects of harmaline along with cinanserin in acute restraint stress-treated mice.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Cinanserin; Depression; Dose-Response | 2021 |
Modulation of sphingosine-1-phosphate receptor ameliorates harmaline-induced essential tremor in rat.
Topics: Animals; Anxiety; Behavior, Animal; Central Nervous System Stimulants; Disease Models, Animal; Essen | 2017 |
Anxiolytic and antidepressant effects of ACPA and harmaline co-treatment.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Anxiety Disorders; Arachidon | 2019 |
Erythropoietin ameliorates harmaline-induced essential tremor and cognition disturbances.
Topics: Animals; Anxiety; Biomechanical Phenomena; Cognition Disorders; Erythropoietin; Essential Tremor; Ex | 2019 |
The therapeutic potential of Berberine chloride hydrate against harmaline-induced motor impairments in a rat model of tremor.
Topics: Animals; Anxiety; Berberine; Essential Tremor; Exploratory Behavior; Gait; Harmaline; Male; Motor Sk | 2015 |
Cannabinoid receptor agonism suppresses tremor, cognition disturbances and anxiety-like behaviors in a rat model of essential tremor.
Topics: Animals; Anti-Anxiety Agents; Anti-Dyskinesia Agents; Anxiety; Avoidance Learning; Benzoxazines; Can | 2016 |
Effects of harmaline on anxiety-related behavior in mice.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Dose-Response Relationship, Drug; Harmalin | 2005 |