harderoporphyrin and Coproporphyria--Hereditary

harderoporphyrin has been researched along with Coproporphyria--Hereditary* in 1 studies

Other Studies

1 other study(ies) available for harderoporphyrin and Coproporphyria--Hereditary

ArticleYear
Identification of monovinyl tripropionic acid porphyrins and metabolites from faeces of patients with hereditary coproporphyria by high-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2004, Volume: 18, Issue:19

    Harderoporphyrin (2-vinyl-4,6,7-tripropionic acid porphyrin) and its metabolites in faeces of patients with hereditary coproporphyria (HCP) have been separated and characterized by high-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry (HPLC/ESI-Q-TOFMS/MS). The metabolites identified were 2-ethyl-4,6,7-tripropionic acid porphyrin, 2-hydro-4,6,7-tripropionic acid porphyrin, 2-methoxyethyl-4,6,7-tripropionic acid porphyrin and 2-acetyl-4,6,7-tripropionic acid porphyrin. Isomers of harderoporphyrin derived from isomerization of harderoporphyrinogen were also detected.

    Topics: Chromatography, High Pressure Liquid; Coproporphyria, Hereditary; Feces; Humans; Porphyrins; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2004