Compounds > halothane
Page last updated: 2024-10-28

halothane and Pheochromocytoma

halothane has been researched along with Pheochromocytoma in 29 studies

Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)

Research Excerpts

ExcerptRelevanceReference
"Halothane and isoflurane enhanced amyloid beta oligomerization rates and pheochromocytoma cytotoxicity in vitro through a preference for binding small oligomeric species."3.72Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity. ( Carnini, A; Eckenhoff, MF; Eckenhoff, RG; Johansson, JS; Kang, B; Keller, JM; Pidikiti, R; Wei, H; Wei, W, 2004)
"In the rat pheochromocytoma cell line PC 12, the effects of four volatile anesthetics (halothane, isoflurane, enflurane, methoxyflurane) on the K+-evoked intracellular calcium [( Ca2+]i) rise were investigated using the Ca2+-sensitive fluorescence dye fura-2."3.67Volatile anesthetics depress the depolarization-induced cytoplasmic calcium rise in PC 12 cells. ( Eckhardt-Wallasch, H; Koschel, K; Kress, HG; Tas, PW, 1987)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199027 (93.10)18.7374
1990's1 (3.45)18.2507
2000's1 (3.45)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
NICOLETTI, RL1
SOARES, PM1
SATO, M1
CRUZ, FN1
ALMEIDA, AR1
ROLLASON, WN1
SCHWEIKERT, CH1
KAPFHAMMER, V1
MURPHY, M1
PRIOR, FN1
JOSEPH, S1
Eckenhoff, RG1
Johansson, JS1
Wei, H1
Carnini, A1
Kang, B1
Wei, W1
Pidikiti, R1
Keller, JM1
Eckenhoff, MF1
Yusa, T1
Kataoka, Y1
Aoba, Y1
Watabe, M1
Gebbie, DM1
Finlayson, DC1
Cadot, M1
Le Polles, R1
Solovei, G1
Logeais, Y1
Gamain, J1
Ossart, M1
Pietri, J1
Baraka, A1
Muallem, M1
Harrison, TS1
Edelist, G1
Kress, HG3
Müller, J1
Eisert, A1
Eckhardt-Wallasch, H1
Tas, PW2
Koschel, K2
Nechaĭ, AI1
Shanin, SS1
Gubin, VV1
Tcherdakoff, P3
Tavernier, M4
Desmonts, JM4
Delort, N3
Vaysse, J4
Milliez, P1
Zeller, K1
Gorodinskaia, VIa1
Amakata, Y1
Sumikawa, K1
Takase, A1
Denlinger, JK1
Lecky, JH1
Nahrwold, ML1
Bingham, W1
Elliott, J1
Lyons, SM1
Andréassian, B1
Caroli, G1
Giovanelli, L1
Brandolin, P1
Coquillaud, JP1
Elbhar, G1
Oyama, T1
Hasegawa, T1
Takiguchi, Y1
Shibata, S1
Kalff, G1
Ristori, M1
Carboncini, P1
Novelli, GP1
Matsunaga, Y1
Teramoto, T1
Mori, N1
Kato, R1
Murase, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Association Between Changes in Cerebral Gray Matter Volume and Postoperative Cognitive Dysfunction in Elderly Patients Following Sevoflurane Anesthesia (POCD-MRI)[NCT02045004]100 participants (Actual)Observational2015-07-14Completed
Release of Serum Neurofilament Light (NFL), Biomarker of Neuronal Injury, in Surgery Under General Anaesthesia (GA) Compared to Surgery With Hypno-analgesia (Hyp): A Prospective, Non-inferiority Study[NCT04500236]100 participants (Anticipated)Interventional2020-09-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for halothane and Pheochromocytoma

ArticleYear
[Combined effect of beta-adrenoblockaders with other pharmacologic agents (review of the literature)].
    Vrachebnoe delo, 1971, Volume: 7

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia, Inhalation; Angina Pectoris;

1971
[Pheochromocytoma and anesthesia].
    Masui. The Japanese journal of anesthesiology, 1974, Volume: 23, Issue:3

    Topics: Adrenal Gland Neoplasms; Anesthesia; Blood Volume; Catecholamines; Halothane; Humans; Methoxyflurane

1974

Other Studies

27 other studies available for halothane and Pheochromocytoma

ArticleYear
[ANESTHESIA IN ADRENALECTOMY].
    Revista brasileira de anestesiologia, 1963, Volume: 13

    Topics: Adrenalectomy; Anesthesia; Anesthesiology; Breast Neoplasms; Cushing Syndrome; Epinephrine; Halothan

1963
HALOTHANE AND PHAEOCHROMOCYTOMA. A CASE REPORT.
    British journal of anaesthesia, 1964, Volume: 36

    Topics: Adrenal Gland Neoplasms; Anesthesia; Anesthesia, Inhalation; Blood Pressure; Blood Pressure Determin

1964
[ON THE PROBLEM OF ADRENAL SURGERY. A CLINICAL AND ANIMAL EXPERIMENTAL STUDY].
    Medizinische Klinik, 1964, Mar-20, Volume: 59

    Topics: Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenalectomy; Adrenogenital Syndrome; Ane

1964
HALOTHANE AND BLOOD TRANSFUSION FOR PHAEOCHROMOCYTOMA: A CASE REPORT.
    British journal of anaesthesia, 1964, Volume: 36

    Topics: Anesthesia; Anesthesia, Inhalation; Anesthesiology; Blood Transfusion; Drug Therapy; Halothane; Huma

1964
Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity.
    Anesthesiology, 2004, Volume: 101, Issue:3

    Topics: Adrenal Gland Neoplasms; Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Central Nervous Sy

2004
Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity.
    Anesthesiology, 2004, Volume: 101, Issue:3

    Topics: Adrenal Gland Neoplasms; Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Central Nervous Sy

2004
Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity.
    Anesthesiology, 2004, Volume: 101, Issue:3

    Topics: Adrenal Gland Neoplasms; Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Central Nervous Sy

2004
Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity.
    Anesthesiology, 2004, Volume: 101, Issue:3

    Topics: Adrenal Gland Neoplasms; Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Central Nervous Sy

2004
[Anesthetic management for the surgery of pheochromocytoma--halothane anesthesia combined with Inderal].
    Masui. The Japanese journal of anesthesiology, 1966, Volume: 15, Issue:2

    Topics: Adult; Anesthesia, Inhalation; Halothane; Humans; Male; Pheochromocytoma; Propranolol

1966
Use of alpha and beta adrenergic blocking drugs and halothane in the anaesthetic management of phaeochromocytoma.
    Canadian Anaesthetists' Society journal, 1967, Volume: 14, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Inhalation; Autonomic Nervous System; Female; Halothane; H

1967
[An answer to Drs Gamain, Ossart and Pietri].
    La Nouvelle presse medicale, 1979, Apr-14, Volume: 8, Issue:17

    Topics: Adrenal Gland Neoplasms; Halothane; Humans; Neuroleptanalgesia; Pheochromocytoma

1979
[Neuroleptanalgesia in pheochromocytoma surgery].
    La Nouvelle presse medicale, 1979, Apr-14, Volume: 8, Issue:17

    Topics: Adrenal Gland Neoplasms; Halothane; Humans; Neuroleptanalgesia; Pheochromocytoma

1979
Hypotensive halothane anaesthesia for surgical excision of pheochromocytoma.
    Middle East journal of anaesthesiology, 1978, Volume: 5, Issue:2

    Topics: Adrenal Gland Neoplasms; Anesthesia, Inhalation; Arrhythmias, Cardiac; Child; Halothane; Humans; Mal

1978
Multiple anaesthetics in a patient with phaeochromocytoma.
    Canadian Anaesthetists' Society journal, 1975, Volume: 22, Issue:6

    Topics: Adrenal Gland Neoplasms; Anesthesia; Anesthesia, Inhalation; Halothane; Humans; Male; Meperidine; Mi

1975
Volatile anesthetics and stimulus-secretion coupling in a neural cell line.
    Annals of the New York Academy of Sciences, 1991, Volume: 625

    Topics: Adrenal Gland Neoplasms; Animals; Calcium; Carbachol; Cell Line; Dopamine; Halothane; Isoflurane; Ki

1991
Volatile anesthetics depress the depolarization-induced cytoplasmic calcium rise in PC 12 cells.
    FEBS letters, 1987, Aug-31, Volume: 221, Issue:1

    Topics: Adrenal Gland Neoplasms; Anesthetics; Animals; Benzofurans; Cell Line; Cytoplasm; Enflurane; Fluores

1987
[Volatile anesthetics and n-alcohols inhibit the uptake of noradrenaline in pheochromocytoma cells].
    Der Anaesthesist, 1987, Volume: 36, Issue:7

    Topics: Adrenal Gland Neoplasms; Alcohols; Anesthetics; Animals; Biological Transport; Cell Line; Enflurane;

1987
[Various features of anesthesiologic provisions for surgery of pheochromocytoma].
    Vestnik khirurgii imeni I. I. Grekova, 1986, Volume: 136, Issue:3

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Anesthesia, General; Ether; Ethyl Ethers; Female;

1986
[Anesthesia and resuscitation in pheochromocytoma].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1972, Jan-26, Volume: 48, Issue:5

    Topics: Adrenal Gland Neoplasms; Anesthesia; Arrhythmias, Cardiac; Blood Pressure; Catecholamines; Halothane

1972
[Anesthesia in chronic patients].
    Bibliotheca tuberculosea, 1969, Volume: 25

    Topics: Adult; Aged; Anesthesia; Anesthetics; Anti-Bacterial Agents; Asthma; Benperidol; Chronic Disease; Fe

1969
Hepatocellular dysfunction without jaundice after enflurane anesthesia.
    Anesthesiology, 1974, Volume: 41, Issue:1

    Topics: Anesthesia, Inhalation; Anesthetics; Chemical and Drug Induced Liver Injury; Halothane; Humans; Hydr

1974
Management of anaesthesia for phaeochromocytoma.
    Anaesthesia, 1972, Volume: 27, Issue:1

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Anesthesia, General; Arrhythmias, Cardiac; Blood Pressur

1972
[Pheochromocytoma of Zuckerkandl's organ].
    Annales de chirurgie, 1971, Volume: 25, Issue:3

    Topics: Abdominal Neoplasms; Adult; Anesthesia, Inhalation; Chromaffin System; Female; Halothane; Humans; Ma

1971
[Pheochromocytoma and fluothane anesthesia].
    Minerva anestesiologica, 1970, Mar-03, Volume: 36, Issue:3

    Topics: Anesthesia, General; Arrhythmias, Cardiac; Blood Pressure; Halothane; Heart; Humans; Male; Middle Ag

1970
[Current state of anesthesia and resuscitation in pheochromocytoma].
    Acquisitions medicales recentes, 1970

    Topics: Adrenal Gland Neoplasms; Anesthesia; Halothane; Heart Arrest; Heart Massage; Humans; Lidocaine; Meth

1970
[Surgery of pheochromocytoma (apropos of a homogenous series of 50 cases)].
    Annales de chirurgie, 1971, Volume: 25, Issue:3

    Topics: Adrenal Gland Neoplasms; Adult; Anesthesia, Inhalation; Aortography; Female; Halothane; Humans; Male

1971
[Experience with anesthesia in surgery of pheochromocytoma--2 cases using fluothane anesthesia].
    Geka chiryo. Surgical therapy, 1967, Volume: 17, Issue:1

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Anesthesia; Catecholamines; Female; Halothane; Humans; M

1967
[Anesthesiologic problems in patients with pheochromocytoma].
    Der Anaesthesist, 1968, Volume: 17, Issue:2

    Topics: Anesthesia; Blood Transfusion; Blood Volume; Blood Volume Determination; Erythrocytes; Halothane; He

1968
[Halothane and pheochromocytoma].
    Acta anaesthesiologica, 1968

    Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Anesthesia; Cardiovascular System;

1968
[Experience with pheochromocytoma presenting an interesting course during anesthesia].
    Shujutsu. Operation, 1966, Volume: 20, Issue:10

    Topics: Adolescent; Anesthesia, Inhalation; Arrhythmias, Cardiac; Halothane; Humans; Male; Pheochromocytoma;

1966