halothane has been researched along with Obesity in 43 studies
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| " All patients whose jaundice may have had an identifiable cause were excluded, which left 76 patients with unexplained hepatitis following halothane anaesthesia (UHFH)." | 7.65 | Unexplained hepatitis following halothane. ( Appleyard, AJ; Doniach, D; Perrin, J; Simpson, BR; Strunin, L; Walton, B, 1976) |
| "To investigate the relationship between total body weight (TBW) or body mass index (BMI) and atracurium reversal time." | 3.70 | Antagonism of atracurium-induced block in obese patients. ( Kirkegaard-Nielsen, H; Lindholm, P; Petersen, HS; Severinsen, IK, 1998) |
| "On the basis of an analysis of changes in biochemical indices of the hepatic function in 41 patients operated upon for obesity of the 3d or 4th stage the authors make a conclusion that ether narcosis exerts a less injuring effect on the liver as compared with fluothane and is believed to be preferable." | 3.66 | [Functional state of the liver in obese patients subjected to surgery under halothane and ether anesthesia]. ( Borovskikh, NA; Koriukin, VM; Miagkova, LM; Sedletskiĭ, IuI, 1983) |
| "A case of halothane hepatitis occurring 14 months after jejunoileal bypass for morbid obesity in a 49-year-old woman is described." | 3.66 | Halothane hepatitis after jejunoileal bypass. ( Hüttel, MS, 1979) |
| " All patients whose jaundice may have had an identifiable cause were excluded, which left 76 patients with unexplained hepatitis following halothane anaesthesia (UHFH)." | 3.65 | Unexplained hepatitis following halothane. ( Appleyard, AJ; Doniach, D; Perrin, J; Simpson, BR; Strunin, L; Walton, B, 1976) |
| "Peak trifluoroacetic acid levels were similar in the two patient groups." | 1.26 | Halothane biotransformation in obese and nonobese patients. ( Bentley, JB; Cork, RC; Gandolfi, AJ; Vaughan, RW, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 39 (90.70) | 18.7374 |
| 1990's | 4 (9.30) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DEJONG, RH | 1 |
| Keen, RI | 1 |
| Jurdi-Nuwayhid, F | 1 |
| Borovskikh, NA | 2 |
| Koriukin, VM | 1 |
| Sedletskiĭ, IuI | 1 |
| Miagkova, LM | 1 |
| Cousins, MJ | 1 |
| Vaughan, RW | 5 |
| Bentley, JB | 4 |
| Gandolfi, AJ | 4 |
| Cork, RC | 3 |
| Borel, JD | 1 |
| Ladegaard-Pedersen, HJ | 1 |
| Touloukian, J | 1 |
| Kaplowitz, N | 1 |
| Pedersen, FM | 1 |
| Gunaratnam, NT | 1 |
| Benson, J | 1 |
| Chen, M | 1 |
| Kirkegaard-Nielsen, H | 1 |
| Lindholm, P | 1 |
| Petersen, HS | 1 |
| Severinsen, IK | 1 |
| Kafer, ER | 1 |
| Marsh, HM | 1 |
| Milliken, RA | 1 |
| Weintraub, DM | 1 |
| Nawaf, K | 1 |
| Stoelting, RK | 2 |
| Mendenhall, MK | 1 |
| Ahlgren, EW | 1 |
| Fee, JP | 1 |
| Black, GW | 1 |
| Dundee, JW | 1 |
| McIlroy, PD | 1 |
| Johnston, HM | 1 |
| Johnston, SB | 1 |
| Black, IH | 1 |
| McNeill, HG | 1 |
| Neill, DW | 1 |
| Doggart, JR | 1 |
| Merrett, JD | 1 |
| McDonald, JR | 1 |
| Bradley, DS | 1 |
| Haire, M | 1 |
| McMillan, SA | 1 |
| Hüttel, MS | 1 |
| Shibolet, S | 1 |
| Lancaster, MC | 1 |
| Danon, Y | 1 |
| Saraiva, RA | 2 |
| Lunn, JN | 2 |
| Mapleson, WW | 2 |
| Willis, BA | 2 |
| France, JM | 1 |
| Young, SR | 1 |
| Peterson, C | 1 |
| Madura, JA | 1 |
| France, JS | 1 |
| Bukhalo, AE | 1 |
| Karaman, NV | 1 |
| Marschall, KE | 1 |
| Mathieu, A | 1 |
| Vandam, LD | 1 |
| Walton, B | 1 |
| Simpson, BR | 1 |
| Strunin, L | 1 |
| Doniach, D | 1 |
| Perrin, J | 1 |
| Appleyard, AJ | 1 |
| Lew, JK | 1 |
| Spence, AA | 1 |
| Elton, RA | 1 |
| Patial, RK | 1 |
| Sarin, R | 1 |
| Patial, SB | 1 |
| Biermann, JS | 1 |
| Rice, SA | 1 |
| Fish, KJ | 1 |
| Serra, MT | 1 |
| Zaric, D | 1 |
| Larsen, SF | 1 |
| Jacobsen, E | 1 |
| Olesen, KH | 1 |
| Ranek, L | 1 |
| Otsuka, S | 1 |
| Yamamoto, M | 1 |
| Kasuya, S | 1 |
| Ohtomo, H | 1 |
| Yamamoto, Y | 1 |
| Yoshida, TO | 1 |
| Akaza, T | 1 |
| Cohen, S | 1 |
| Jackson, DC | 1 |
| Cascorbi, HF | 1 |
| Joshi, PH | 1 |
| Conn, HO | 1 |
| Wulfsohn, NL | 1 |
| Hagelsten, JO | 1 |
| Hansen, H | 1 |
| Fisher, J | 1 |
| James, ML | 1 |
| Göltner, E | 1 |
| Babenerd, J | 1 |
| van Acken, G | 1 |
| McIntyre, JW | 1 |
3 reviews available for halothane and Obesity
| Article | Year |
|---|---|
Halothane hepatitis: what's new?
Topics: Animals; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug Interactions; Halothane | 1980 |
Heat stroke: a review.
Topics: Acclimatization; Adult; Age Factors; Animals; Body Temperature; Body Temperature Regulation; Brain; | 1976 |
Factors causing differences in halothane biotransformation.
Topics: Anesthesia, Inhalation; Anesthesiology; Animals; Biotransformation; Carbon Radioisotopes; Cytochrome | 1974 |
3 trials available for halothane and Obesity
| Article | Year |
|---|---|
Does evidence of reductive halothane biotransformation correlate with hepatic binding of metabolites in obese patients?
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Biotransformation; Enflurane; Fentanyl; Fl | 1981 |
General anesthesia for morbidly obese patients--an examination of postoperative outcomes.
Topics: Adult; Anesthesia, General; Blood Gas Analysis; Enflurane; Female; Fentanyl; Halothane; Humans; Male | 1981 |
Blood gas changes during spinal and epidural analgesia.
Topics: Adult; Aged; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Spinal; Carbon Dioxide; Cardia | 1969 |
37 other studies available for halothane and Obesity
| Article | Year |
|---|---|
ARTERIAL CARBON DIOXIDE AND OXYGEN TENSIONS DURING SPINAL BLOCK.
Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Gas Analysis; Carbon Diox | 1965 |
Warm-water cooling.
Topics: Adolescent; Adult; Aged; Body Temperature; Child; Chlorpromazine; Craniopharyngioma; Halothane; Hot | 1966 |
Untoward side effects and toxicities of inhalational anesthetics.
Topics: Anesthesia, Inhalation; Anesthetics; Carcinogens; Chemical and Drug Induced Liver Injury; Enflurane; | 1984 |
[Functional state of the liver in obese patients subjected to surgery under halothane and ether anesthesia].
Topics: Adult; Anesthesia, Inhalation; Ether; Ethyl Ethers; Halothane; Humans; Ileum; Jejunum; Liver; Liver | 1983 |
Biochemical and biotransformation alterations in obesity.
Topics: Anesthetics; Biotransformation; Enflurane; Female; Glucose; Halothane; Humans; Lipids; Liver; Male; | 1982 |
Halothane biotransformation in obese and nonobese patients.
Topics: Adult; Biotransformation; Bromides; Female; Fluorides; Halothane; Humans; Male; Obesity; Oxidation-R | 1982 |
Enflurane blood-gas solubility: influence of weight and hemoglobin.
Topics: Adult; Body Weight; Enflurane; Gases; Halothane; Hemoglobins; Humans; Obesity; Solubility | 1982 |
Recovery from general anesthesia in obese patients.
Topics: Halothane; Humans; Obesity | 1981 |
Halothane-induced hepatic disease.
Topics: Adolescent; Adult; Age Factors; Aged; Chemical and Drug Induced Liver Injury; Diagnosis, Differentia | 1981 |
[Halothane and obese patients].
Topics: Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Halothane; Humans; Obesity; Risk Fa | 1995 |
Suspected isoflurane hepatitis in an obese patient with a history of halothane hepatitis.
Topics: Chemical and Drug Induced Liver Injury; Cross Reactions; Halothane; Humans; Isoflurane; Male; Middle | 1995 |
Antagonism of atracurium-induced block in obese patients.
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Atracurium; Body Mass Index; Body Weight; | 1998 |
The effects of anesthetic drugs and disease on the chemical regulation of ventilation.
Topics: Anesthetics; Anti-Anxiety Agents; Autonomic Nervous System; Barbiturates; Benzodiazepines; Carbon Di | 1977 |
Cardiac abnormalities during anesthesia in a child with Prader-Willi syndrome.
Topics: Anesthesia, General; Blood Pressure; Child; Child, Preschool; Cryptorchidism; Halothane; Heart Defec | 1975 |
SGOT values following evidence of reductive biotransformation of halothane in man.
Topics: Aspartate Aminotransferases; Biotransformation; Fluorides; Halothane; Humans; Obesity; Oxidation-Red | 1979 |
Anesthetic considerations in surgery for gastrointestinal disease.
Topics: Aged; Anesthetics; Drug Interactions; Enflurane; Female; Gastrointestinal Diseases; Halothane; Human | 1979 |
A prospective study of liver enzyme and other changes following repeat administration of halothane and enflurane.
Topics: Aged; Alcohol Drinking; Anesthesia, Inhalation; Enflurane; Female; Halothane; Humans; Liver; Male; M | 1979 |
Halothane hepatitis after jejunoileal bypass.
Topics: Autoimmune Diseases; Chemical and Drug Induced Liver Injury; Female; Halothane; Humans; Ileum; Immun | 1979 |
Adiposity and the pharmacokinetics of halothane. The effect of adiposity on the maintenance of and recovery from halothane anaesthesia.
Topics: Adolescent; Adult; Age Factors; Aged; Anesthesia, Inhalation; Halothane; Humans; Middle Aged; Obesit | 1977 |
Anesthetic biotransformation and renal function in obese patients during and after methoxyflurane or halothane anesthesia.
Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Inhalation; Biopsy, Needle; Biotransformation; Fatty Liver | 1975 |
Proceedings: The effect of obesity on the uptake of halothane during maintenance of anaesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Halothane; Humans; Middle Aged; Obesity | 1975 |
[Effect of different types of anesthesia on hemodynamics and certain indicators of metabolism in obesity].
Topics: Adult; Aged; Anesthesia; Anesthesia, Endotracheal; Anesthesia, Local; Blood Glucose; Ether; Female; | 1975 |
Recurrent hepatitis B-negative hepatitis after halothane anesthesia: apparent failure to demonstrate altered sensitivity.
Topics: Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Female; Halothane; Hepatitis B Antig | 1976 |
Unexplained hepatitis following halothane.
Topics: Adolescent; Adult; Age Factors; Aged; Anesthesia, Inhalation; Autoantibodies; Child; Child, Preschoo | 1976 |
Cross-sectional study of complications of inhalational anaesthesia in 16,995 patients.
Topics: Adolescent; Adult; Age Factors; Aged; Anesthesia, Inhalation; Anesthesiology; Child; Cross-Sectional | 1991 |
Halothane associated hepatitis and phenobarbitone.
Topics: Adult; Anesthesia, Obstetrical; Chemical and Drug Induced Liver Injury; Drug Synergism; Female; Halo | 1989 |
Metabolism of halothane in obese Fischer 344 rats.
Topics: Animals; Bromides; Dietary Fats; Fluorides; Halothane; Male; Obesity; Oxidation-Reduction; Rats; Rat | 1989 |
[Changes in cardiohemodynamics in obese patients in response to fluothane, ether and neuroleptanalgesia].
Topics: Abdomen; Adult; Depression, Chemical; Ether; Ethyl Ethers; Halothane; Hemodynamics; Humans; Myocardi | 1987 |
Halothane hepatitis in a prospective study of postoperative complications.
Topics: Aged; Alanine Transaminase; Anesthesia, General; Chemical and Drug Induced Liver Injury; Female; Hal | 1986 |
HLA antigens in patients with unexplained hepatitis following halothane anesthesia.
Topics: Adolescent; Adult; Aged; Anesthetics; Chemical and Drug Induced Liver Injury; Child; Cholestasis, In | 1985 |
Emergency cesarean section for fetal distress.
Topics: Adult; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Drug I | 1986 |
Hypoxaemia in the immediate postoperative period.
Topics: Abdominal Muscles; Adolescent; Adult; Age Factors; Aged; Anesthesia, General; Female; Halothane; Hea | 1968 |
The syndrome of methoxyflurane-associated hepatitis.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Drug Hypersensitivity; | 1974 |
Succinylcholine dosage based on lean body mass.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Apnea; Body Weight; Female; Halothane; Humans; Intubat | 1972 |
[Obesity and anesthesia].
Topics: Adult; Anesthesia; Cyclopropanes; Female; Halothane; Humans; Ileostomy; Intubation, Intratracheal; J | 1969 |
[The significance of hypertension in gynecological operations].
Topics: Adult; Age Factors; Aged; Anesthesia, Endotracheal; Anesthesia, Spinal; Blood Chemical Analysis; Blo | 1967 |
Problems for the anaesthetist in the care of the obese patient.
Topics: Anesthesia, General; Blood Pressure Determination; Body Height; Body Weight; Fentanyl; Halothane; Hu | 1968 |