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halothane and Obesity

halothane has been researched along with Obesity in 43 studies

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
" All patients whose jaundice may have had an identifiable cause were excluded, which left 76 patients with unexplained hepatitis following halothane anaesthesia (UHFH)."7.65Unexplained hepatitis following halothane. ( Appleyard, AJ; Doniach, D; Perrin, J; Simpson, BR; Strunin, L; Walton, B, 1976)
"To investigate the relationship between total body weight (TBW) or body mass index (BMI) and atracurium reversal time."3.70Antagonism of atracurium-induced block in obese patients. ( Kirkegaard-Nielsen, H; Lindholm, P; Petersen, HS; Severinsen, IK, 1998)
"On the basis of an analysis of changes in biochemical indices of the hepatic function in 41 patients operated upon for obesity of the 3d or 4th stage the authors make a conclusion that ether narcosis exerts a less injuring effect on the liver as compared with fluothane and is believed to be preferable."3.66[Functional state of the liver in obese patients subjected to surgery under halothane and ether anesthesia]. ( Borovskikh, NA; Koriukin, VM; Miagkova, LM; Sedletskiĭ, IuI, 1983)
"A case of halothane hepatitis occurring 14 months after jejunoileal bypass for morbid obesity in a 49-year-old woman is described."3.66Halothane hepatitis after jejunoileal bypass. ( Hüttel, MS, 1979)
" All patients whose jaundice may have had an identifiable cause were excluded, which left 76 patients with unexplained hepatitis following halothane anaesthesia (UHFH)."3.65Unexplained hepatitis following halothane. ( Appleyard, AJ; Doniach, D; Perrin, J; Simpson, BR; Strunin, L; Walton, B, 1976)
"Peak trifluoroacetic acid levels were similar in the two patient groups."1.26Halothane biotransformation in obese and nonobese patients. ( Bentley, JB; Cork, RC; Gandolfi, AJ; Vaughan, RW, 1982)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199039 (90.70)18.7374
1990's4 (9.30)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DEJONG, RH1
Keen, RI1
Jurdi-Nuwayhid, F1
Borovskikh, NA2
Koriukin, VM1
Sedletskiĭ, IuI1
Miagkova, LM1
Cousins, MJ1
Vaughan, RW5
Bentley, JB4
Gandolfi, AJ4
Cork, RC3
Borel, JD1
Ladegaard-Pedersen, HJ1
Touloukian, J1
Kaplowitz, N1
Pedersen, FM1
Gunaratnam, NT1
Benson, J1
Chen, M1
Kirkegaard-Nielsen, H1
Lindholm, P1
Petersen, HS1
Severinsen, IK1
Kafer, ER1
Marsh, HM1
Milliken, RA1
Weintraub, DM1
Nawaf, K1
Stoelting, RK2
Mendenhall, MK1
Ahlgren, EW1
Fee, JP1
Black, GW1
Dundee, JW1
McIlroy, PD1
Johnston, HM1
Johnston, SB1
Black, IH1
McNeill, HG1
Neill, DW1
Doggart, JR1
Merrett, JD1
McDonald, JR1
Bradley, DS1
Haire, M1
McMillan, SA1
Hüttel, MS1
Shibolet, S1
Lancaster, MC1
Danon, Y1
Saraiva, RA2
Lunn, JN2
Mapleson, WW2
Willis, BA2
France, JM1
Young, SR1
Peterson, C1
Madura, JA1
France, JS1
Bukhalo, AE1
Karaman, NV1
Marschall, KE1
Mathieu, A1
Vandam, LD1
Walton, B1
Simpson, BR1
Strunin, L1
Doniach, D1
Perrin, J1
Appleyard, AJ1
Lew, JK1
Spence, AA1
Elton, RA1
Patial, RK1
Sarin, R1
Patial, SB1
Biermann, JS1
Rice, SA1
Fish, KJ1
Serra, MT1
Zaric, D1
Larsen, SF1
Jacobsen, E1
Olesen, KH1
Ranek, L1
Otsuka, S1
Yamamoto, M1
Kasuya, S1
Ohtomo, H1
Yamamoto, Y1
Yoshida, TO1
Akaza, T1
Cohen, S1
Jackson, DC1
Cascorbi, HF1
Joshi, PH1
Conn, HO1
Wulfsohn, NL1
Hagelsten, JO1
Hansen, H1
Fisher, J1
James, ML1
Göltner, E1
Babenerd, J1
van Acken, G1
McIntyre, JW1

Reviews

3 reviews available for halothane and Obesity

ArticleYear
Halothane hepatitis: what's new?
    Drugs, 1980, Volume: 19, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug Interactions; Halothane

1980
Heat stroke: a review.
    Aviation, space, and environmental medicine, 1976, Volume: 47, Issue:3

    Topics: Acclimatization; Adult; Age Factors; Animals; Body Temperature; Body Temperature Regulation; Brain;

1976
Factors causing differences in halothane biotransformation.
    International anesthesiology clinics, 1974,Summer, Volume: 12, Issue:2

    Topics: Anesthesia, Inhalation; Anesthesiology; Animals; Biotransformation; Carbon Radioisotopes; Cytochrome

1974

Trials

3 trials available for halothane and Obesity

ArticleYear
Does evidence of reductive halothane biotransformation correlate with hepatic binding of metabolites in obese patients?
    Anesthesia and analgesia, 1981, Volume: 60, Issue:8

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Biotransformation; Enflurane; Fentanyl; Fl

1981
General anesthesia for morbidly obese patients--an examination of postoperative outcomes.
    Anesthesiology, 1981, Volume: 54, Issue:4

    Topics: Adult; Anesthesia, General; Blood Gas Analysis; Enflurane; Female; Fentanyl; Halothane; Humans; Male

1981
Blood gas changes during spinal and epidural analgesia.
    Anaesthesia, 1969, Volume: 24, Issue:4

    Topics: Adult; Aged; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Spinal; Carbon Dioxide; Cardia

1969

Other Studies

37 other studies available for halothane and Obesity

ArticleYear
ARTERIAL CARBON DIOXIDE AND OXYGEN TENSIONS DURING SPINAL BLOCK.
    JAMA, 1965, Mar-01, Volume: 191

    Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Gas Analysis; Carbon Diox

1965
Warm-water cooling.
    Acta anaesthesiologica Scandinavica. Supplementum, 1966, Volume: 23

    Topics: Adolescent; Adult; Aged; Body Temperature; Child; Chlorpromazine; Craniopharyngioma; Halothane; Hot

1966
Untoward side effects and toxicities of inhalational anesthetics.
    Middle East journal of anaesthesiology, 1984, Volume: 7, Issue:4

    Topics: Anesthesia, Inhalation; Anesthetics; Carcinogens; Chemical and Drug Induced Liver Injury; Enflurane;

1984
[Functional state of the liver in obese patients subjected to surgery under halothane and ether anesthesia].
    Vestnik khirurgii imeni I. I. Grekova, 1983, Volume: 130, Issue:2

    Topics: Adult; Anesthesia, Inhalation; Ether; Ethyl Ethers; Halothane; Humans; Ileum; Jejunum; Liver; Liver

1983
Biochemical and biotransformation alterations in obesity.
    Contemporary anesthesia practice, 1982, Volume: 5

    Topics: Anesthetics; Biotransformation; Enflurane; Female; Glucose; Halothane; Humans; Lipids; Liver; Male;

1982
Halothane biotransformation in obese and nonobese patients.
    Anesthesiology, 1982, Volume: 57, Issue:2

    Topics: Adult; Biotransformation; Bromides; Female; Fluorides; Halothane; Humans; Male; Obesity; Oxidation-R

1982
Enflurane blood-gas solubility: influence of weight and hemoglobin.
    Anesthesia and analgesia, 1982, Volume: 61, Issue:12

    Topics: Adult; Body Weight; Enflurane; Gases; Halothane; Hemoglobins; Humans; Obesity; Solubility

1982
Recovery from general anesthesia in obese patients.
    Anesthesiology, 1981, Volume: 55, Issue:6

    Topics: Halothane; Humans; Obesity

1981
Halothane-induced hepatic disease.
    Seminars in liver disease, 1981, Volume: 1, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Chemical and Drug Induced Liver Injury; Diagnosis, Differentia

1981
[Halothane and obese patients].
    Ugeskrift for laeger, 1995, Nov-20, Volume: 157, Issue:47

    Topics: Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Halothane; Humans; Obesity; Risk Fa

1995
Suspected isoflurane hepatitis in an obese patient with a history of halothane hepatitis.
    Anesthesiology, 1995, Volume: 83, Issue:6

    Topics: Chemical and Drug Induced Liver Injury; Cross Reactions; Halothane; Humans; Isoflurane; Male; Middle

1995
Antagonism of atracurium-induced block in obese patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:1

    Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Atracurium; Body Mass Index; Body Weight;

1998
The effects of anesthetic drugs and disease on the chemical regulation of ventilation.
    International anesthesiology clinics, 1977,Summer, Volume: 15, Issue:2

    Topics: Anesthetics; Anti-Anxiety Agents; Autonomic Nervous System; Barbiturates; Benzodiazepines; Carbon Di

1977
Cardiac abnormalities during anesthesia in a child with Prader-Willi syndrome.
    Anesthesiology, 1975, Volume: 43, Issue:5

    Topics: Anesthesia, General; Blood Pressure; Child; Child, Preschool; Cryptorchidism; Halothane; Heart Defec

1975
SGOT values following evidence of reductive biotransformation of halothane in man.
    Anesthesiology, 1979, Volume: 51, Issue:2

    Topics: Aspartate Aminotransferases; Biotransformation; Fluorides; Halothane; Humans; Obesity; Oxidation-Red

1979
Anesthetic considerations in surgery for gastrointestinal disease.
    The Surgical clinics of North America, 1979, Volume: 59, Issue:5

    Topics: Aged; Anesthetics; Drug Interactions; Enflurane; Female; Gastrointestinal Diseases; Halothane; Human

1979
A prospective study of liver enzyme and other changes following repeat administration of halothane and enflurane.
    British journal of anaesthesia, 1979, Volume: 51, Issue:12

    Topics: Aged; Alcohol Drinking; Anesthesia, Inhalation; Enflurane; Female; Halothane; Humans; Liver; Male; M

1979
Halothane hepatitis after jejunoileal bypass.
    Acta chirurgica Scandinavica, 1979, Volume: 145, Issue:7

    Topics: Autoimmune Diseases; Chemical and Drug Induced Liver Injury; Female; Halothane; Humans; Ileum; Immun

1979
Adiposity and the pharmacokinetics of halothane. The effect of adiposity on the maintenance of and recovery from halothane anaesthesia.
    Anaesthesia, 1977, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Anesthesia, Inhalation; Halothane; Humans; Middle Aged; Obesit

1977
Anesthetic biotransformation and renal function in obese patients during and after methoxyflurane or halothane anesthesia.
    Anesthesiology, 1975, Volume: 42, Issue:4

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Inhalation; Biopsy, Needle; Biotransformation; Fatty Liver

1975
Proceedings: The effect of obesity on the uptake of halothane during maintenance of anaesthesia.
    British journal of anaesthesia, 1975, Volume: 47, Issue:9

    Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Halothane; Humans; Middle Aged; Obesity

1975
[Effect of different types of anesthesia on hemodynamics and certain indicators of metabolism in obesity].
    Vestnik khirurgii imeni I. I. Grekova, 1975, Volume: 115, Issue:11

    Topics: Adult; Aged; Anesthesia; Anesthesia, Endotracheal; Anesthesia, Local; Blood Glucose; Ether; Female;

1975
Recurrent hepatitis B-negative hepatitis after halothane anesthesia: apparent failure to demonstrate altered sensitivity.
    Anesthesiology, 1976, Volume: 44, Issue:4

    Topics: Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Female; Halothane; Hepatitis B Antig

1976
Unexplained hepatitis following halothane.
    British medical journal, 1976, May-15, Volume: 1, Issue:6019

    Topics: Adolescent; Adult; Age Factors; Aged; Anesthesia, Inhalation; Autoantibodies; Child; Child, Preschoo

1976
Cross-sectional study of complications of inhalational anaesthesia in 16,995 patients.
    Anaesthesia, 1991, Volume: 46, Issue:10

    Topics: Adolescent; Adult; Age Factors; Aged; Anesthesia, Inhalation; Anesthesiology; Child; Cross-Sectional

1991
Halothane associated hepatitis and phenobarbitone.
    The Journal of the Association of Physicians of India, 1989, Volume: 37, Issue:7

    Topics: Adult; Anesthesia, Obstetrical; Chemical and Drug Induced Liver Injury; Drug Synergism; Female; Halo

1989
Metabolism of halothane in obese Fischer 344 rats.
    Anesthesiology, 1989, Volume: 71, Issue:3

    Topics: Animals; Bromides; Dietary Fats; Fluorides; Halothane; Male; Obesity; Oxidation-Reduction; Rats; Rat

1989
[Changes in cardiohemodynamics in obese patients in response to fluothane, ether and neuroleptanalgesia].
    Vestnik khirurgii imeni I. I. Grekova, 1987, Volume: 138, Issue:3

    Topics: Abdomen; Adult; Depression, Chemical; Ether; Ethyl Ethers; Halothane; Hemodynamics; Humans; Myocardi

1987
Halothane hepatitis in a prospective study of postoperative complications.
    Acta anaesthesiologica Scandinavica, 1986, Volume: 30, Issue:7

    Topics: Aged; Alanine Transaminase; Anesthesia, General; Chemical and Drug Induced Liver Injury; Female; Hal

1986
HLA antigens in patients with unexplained hepatitis following halothane anesthesia.
    Acta anaesthesiologica Scandinavica, 1985, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthetics; Chemical and Drug Induced Liver Injury; Child; Cholestasis, In

1985
Emergency cesarean section for fetal distress.
    Middle East journal of anaesthesiology, 1986, Volume: 8, Issue:4

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Drug I

1986
Hypoxaemia in the immediate postoperative period.
    The Medical journal of Australia, 1968, Jun-15, Volume: 1, Issue:24

    Topics: Abdominal Muscles; Adolescent; Adult; Age Factors; Aged; Anesthesia, General; Female; Halothane; Hea

1968
The syndrome of methoxyflurane-associated hepatitis.
    Annals of internal medicine, 1974, Volume: 80, Issue:3

    Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Drug Hypersensitivity;

1974
Succinylcholine dosage based on lean body mass.
    Canadian Anaesthetists' Society journal, 1972, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Apnea; Body Weight; Female; Halothane; Humans; Intubat

1972
[Obesity and anesthesia].
    Nordisk medicin, 1969, Mar-27, Volume: 81, Issue:13

    Topics: Adult; Anesthesia; Cyclopropanes; Female; Halothane; Humans; Ileostomy; Intubation, Intratracheal; J

1969
[The significance of hypertension in gynecological operations].
    Geburtshilfe und Frauenheilkunde, 1967, Volume: 27, Issue:10

    Topics: Adult; Age Factors; Aged; Anesthesia, Endotracheal; Anesthesia, Spinal; Blood Chemical Analysis; Blo

1967
Problems for the anaesthetist in the care of the obese patient.
    Canadian Anaesthetists' Society journal, 1968, Volume: 15, Issue:4

    Topics: Anesthesia, General; Blood Pressure Determination; Body Height; Body Weight; Fentanyl; Halothane; Hu

1968