Page last updated: 2024-10-28

halothane and Neoplasm Metastasis

halothane has been researched along with Neoplasm Metastasis in 14 studies

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
" The results indicated that two of the anesthetic drugs used during excision of the Lewis lung carcinoma (3LL) tumor, halothane and ketamine, decreased NK activity, whereas the other two, thiopental sodium and N2O, had no effect on NK activity in in vitro assays."3.67General anesthesia during excision of a mouse tumor accelerates postsurgical growth of metastases by suppression of natural killer cell activity. ( Feldman, M; Katzav, S; Segal, S; Shapiro, J, 1986)
"Ketamine was most deleterious, and its effects were prevented by peripheral blockade of beta-adrenoceptors combined with low levels of immunostimulation."1.32Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures. ( Bar-Yosef, S; Ben-Eliyahu, S; Melamed, R; Shakhar, G; Shakhar, K, 2003)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199013 (92.86)18.7374
1990's0 (0.00)18.2507
2000's1 (7.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Melamed, R1
Bar-Yosef, S1
Shakhar, G1
Shakhar, K1
Ben-Eliyahu, S1
Jennett, WB2
McDowall, DG2
Barker, J2
Frid, IA4
Evtiukhin, AI2
Bernshteĭn, MI1
Rudakov, VF1
Dunaevskiĭ, IV1
Shapiro, J2
Jersky, J1
Katzav, S2
Feldman, M2
Segal, S2
Vagner, RI1
Barchuk, AS1
Shul'ga, NI1
Lundy, J2
Lovett, EJ2
Wolinsky, SM1
Conran, P2
Hamilton, S1
Mason, RA1
Steane, PA1
Fitch, W1
Iaremenko, KV2
Arthur, DS1
Stephens, CA1
Brummitt, WM1
Steward, DJ1
Norman, MG1
Taylor, TH1
Styles, M1
Lamming, AJ1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Epidural Anesthesia-analgesia on Long-term Outcome in Elderly Patients After Surgery: 5-year Follow-up of a Multicenter Randomized Controlled Trial[NCT03012945]1,802 participants (Actual)Interventional2014-11-01Completed
A Prospective, Randomized, Controlled Trial to Compare the Effect of TIVA Propofol vs Sevoflurane Anaesthetic on Serumserum Biomarkers and on PBMCs in Patients Undergoing Breast Cancer Resection Surgery[NCT03005860]0 participants (Actual)Interventional2017-01-01Withdrawn (stopped due to Funding could not be arranged, so the study was prematurely terminated)
A Randomized, Open-label Study to Compare Propofol Anesthesia With Sevoflurane Anesthesia in Terms of Overall Survival in Patients With Surgical Intervention for Either Breast-, Colon- or Rectal Cancer[NCT01975064]Phase 45,774 participants (Actual)Interventional2013-11-30Completed
Impact of Epidural Anesthesia-analgesia on Long-term Outcomes in Elderly Patients After Surgery: 5-year Follow-up of a Multicenter Randomized Controlled Trial[NCT03335826]1,802 participants (Actual)Interventional2017-08-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for halothane and Neoplasm Metastasis

ArticleYear
Effect of anaesthesia on intracranial pressure in patients with space-occupying lesions.
    Lancet (London, England), 1969, Jan-11, Volume: 1, Issue:7585

    Topics: Adolescent; Adult; Aged; Anesthesia, Endotracheal; Benperidol; Blood Pressure; Blood Volume; Brain A

1969
[Effect of the anesthesia on tumor metastasis following operative interventions].
    Voprosy onkologii, 1974, Volume: 20, Issue:4

    Topics: Anesthesia; Animals; Breast Neoplasms; Carcinoma, Ehrlich Tumor; Clinical Trials as Topic; Ether; Fe

1974

Other Studies

12 other studies available for halothane and Neoplasm Metastasis

ArticleYear
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe

2003
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe

2003
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe

2003
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe

2003
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe

2003
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe

2003
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe

2003
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe

2003
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe

2003
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe

2003
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe

2003
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe

2003
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe

2003
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe

2003
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe

2003
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe

2003
The effect of halothane on intracranial pressure in cerebral tumors. Report of two cases.
    Journal of neurosurgery, 1967, Volume: 26, Issue:2

    Topics: Adult; Astrocytoma; Brain Neoplasms; Cerebrospinal Fluid; Female; Halothane; Humans; Intracranial Pr

1967
[Effect of anesthesia on a neoplastic process in an experiment].
    Eksperimental'naia onkologiia, 1984, Volume: 6, Issue:3

    Topics: Anesthesia, Inhalation; Animals; Chloroform; Ether; Halothane; Lymphoma, Non-Hodgkin; Methoxyflurane

1984
Anesthetic drugs accelerate the progression of postoperative metastases of mouse tumors.
    The Journal of clinical investigation, 1981, Volume: 68, Issue:3

    Topics: Anesthetics; Animals; Halothane; Liver Neoplasms; Lung Neoplasms; Male; Mice; Neoplasm Metastasis; N

1981
[Effect of the type of anesthesia on the long-term results of surgical treatment of lung cancer patients].
    Voprosy onkologii, 1981, Volume: 27, Issue:11

    Topics: Adenocarcinoma; Anesthesia, General; Carcinoma, Squamous Cell; Ethyl Ethers; Halothane; Humans; Lung

1981
Immune impairment and metastatic tumor growth: the need for an immunorestorative drug as an adjunct to surgery.
    Cancer, 1979, Volume: 43, Issue:3

    Topics: Animals; Antibodies, Neoplasm; Antibody Specificity; Cytotoxicity, Immunologic; Female; Fibrosarcoma

1979
Halothane, surgery, immunosuppression and artificial pulmonary metastases.
    Cancer, 1978, Volume: 41, Issue:3

    Topics: Animals; Female; Halothane; Immunity, Cellular; Immunosuppression Therapy; Immunosuppressive Agents;

1978
Carcinoid syndrome: its relevance to the anaesthetist.
    Anaesthesia, 1976, Volume: 31, Issue:2

    Topics: Anesthesia, General; Anesthetics; Blood Circulation; Bradykinin; Brain Stem; Halothane; Humans; Hypo

1976
General anesthesia during excision of a mouse tumor accelerates postsurgical growth of metastases by suppression of natural killer cell activity.
    Israel journal of medical sciences, 1986, Volume: 22, Issue:5

    Topics: Anesthesia, General; Anesthetics; Animals; Carcinoma; Female; Halothane; In Vitro Techniques; Ketami

1986
[Metastasis of experimental tumors and the functional activity of the hypophysis-adrenal system].
    Voprosy onkologii, 1973, Volume: 19, Issue:10

    Topics: Adrenocorticotropic Hormone; Anesthesia, General; Animals; Antineoplastic Agents; Corticosterone; Et

1973
Fatal tumor embolism during examination under anesthesia.
    Surgery, 1973, Volume: 74, Issue:3

    Topics: Anesthesia, Inhalation; Atropine; Biopsy; Female; Halothane; Humans; Iliac Vein; Infant; Liver Neopl

1973
Sodium nitroprusside as a hypotensive agent in general anaesthesia.
    British journal of anaesthesia, 1970, Volume: 42, Issue:10

    Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Child; Female; Ferricyanides; Halothane; Humans; Hy

1970