halothane has been researched along with Necrosis in 149 studies
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
Excerpt | Relevance | Reference |
---|---|---|
"Foci of necrosis have been observed in the liver of 50% of enzyme-induced rats treated with halothane." | 7.66 | Hepatic necrosis in rats following halothane administration: protective effect of diethyldithiocarbamate. ( Eade, OE; Lucas, K; Millward-Sadler, GH; Mitchell, J; Wright, R, 1980) |
"The effect of halothane anesthesia on myocardial necrosis resulting from coronary artery ligation was examined in 28 anesthetized mongrel dogs." | 7.66 | The effect of halothane anesthesia on myocardial necrosis, hemodynamic performance, and regional myocardial blood flow in dogs following coronary artery occlusion. ( Davis, RF; DeBoer, LW; Lowenstein, E; Maroko, PR; Rude, RE, 1983) |
"8% enflurane, or 1% halothane in 21% oxygen (air) for two hours resulted in hepatic centrilobular necrosis." | 7.66 | Isoflurane and enflurane-induced hepatic necrosis in triiodothyronine-pretreated rats. ( Berman, ML; Holaday, DA; Kuhnert, L; Phythyon, JM, 1983) |
"Administration of anesthetic doses of halothane to hyperthyroid male rats results in the development of hepatic necrosis." | 7.66 | Characterization of hyperthyroidism enhancement of halothane-induced hepatotoxicity. ( Berman, ML; Harbison, RD; James, RC; Smith, AC, 1983) |
"Exposure of phenobarbital-pretreated male Sprague-Dawley rats to halothane, 1 per cent, for two hours under conditions of hypoxia (FIO2 0." | 7.66 | An animal model of halothane hepatotoxicity: roles of enzyme induction and hypoxia. ( Brown, BR; McLain, GE; Sipes, IG, 1979) |
"Hepatic centrilobular necrosis developed in rats pretreated with triiodothyronine (T3) and then anesthetized with halothane, 1 per cent, for two hours at an ambient oxygen concentration." | 7.66 | Halothane-induced hepatic necrosis in triiodothyronine-pretreated rats. ( Berman, ML; Harbison, RD; Hoyle, P; Phythyon, JM; Wood, AJ; Wood, M, 1980) |
"Liver necrosis and an increase of serum sorbitol dehydrogenase activity can be produced in rats by halothane anesthesia (1% v/v in oxygen) following pretreatment with polychlorinated biphenyls." | 7.66 | [Prevention by metyrapone of halothane induced liver necrosis in rats (author's transl)]. ( Krüger, R; Nastainczyk, W; Rendic, S; Ullrich, V, 1982) |
"Analysis of data derived from 130 reports of jaundice occurring after anaesthesia with halothane showed a significant relation between the number of exposures to this anaesthetic and the rapidity with which jaundice develops after exposure." | 7.65 | Jaundice after repeated exposure to halothane: an analysis of Reports to the Committee on Safety of Medicines. ( Inman, WH; Mushin, WW, 1974) |
"5 or 23 mmol/kg) and sacrificed 24 h after dosing exhibited liver toxicity." | 5.26 | A study of the mechanism of halothane-induced liver necrosis. Role of covalent binding of halothane metabolites to liver proteins in the rat. ( Rao, GS, 1977) |
" We present a case report wherein a person who sustained avulsion injury to his left hand in an industrial accident, died due to, fulminant hepatitis, hepatic encephalopathy and acute renal failure, having undergone six operations under general anesthesia with halothane during his stay in the hospital." | 3.73 | Fulminant hepatic failure following halothane anaesthesia. ( Bhat, VJ; Kumar, GP; Sowdi, V, 2005) |
"The liver of all rats given halothane (14% O(2)) had extensive centrilobular necrosis and denaturation." | 3.73 | Ca2+ cytochemical changes of hepatotoxicity caused by halothane and sevoflurane in enzyme-induced hypoxic rats. ( Li, Q; Liu, ZQ; Yang, LQ; Yu, WF; Zhou, MT, 2005) |
"The basis for susceptibility to halothane-induced liver necrosis in guinea-pigs was examined." | 3.69 | Halothane-induced liver injury in guinea-pigs: importance of cytochrome P450 enzyme activity and hepatic blood flow. ( Farrell, GC; Field, J; Frost, L; Mahoney, J; Tapner, M; Weltman, M, 1996) |
"In vivo covalent binding of halothane biotransformation-reactive intermediates to hepatic protein and lipid was examined in association with the subsequent development of hepatic necrosis in the guinea pig." | 3.68 | Covalent binding of oxidative biotransformation intermediates is associated with halothane hepatotoxicity in guinea pigs. ( Gandolfi, AJ; Hall, PD; Lind, RC, 1990) |
"Exposure of guinea pigs to 1% halothane in air for 4 hr resulted in extensive centrizonal hepatic necrosis in 70% of animals examined 2 to 3 days later." | 3.67 | Altered hepatic calcium homeostasis in guinea pigs with halothane-induced hepatotoxicity. ( Bilous, M; Farrell, GC; Frost, L; Mahoney, J, 1988) |
"A report is given on a 24 year old nurse, who developed two episodes of fever, chills and malaise with high serum enzyme levels and histologic proof of extensive centrolobular hepatic necrosis in association with vocational halothane exposure in the operating theatre." | 3.67 | [Centrolobular liver cell necroses following occupational halothane contact. Association with antibodies to halothane altered liver cell components]. ( Börsch, G; Müller, KM; Neuberger, J; Ricken, D; Schmidt, G, 1985) |
"Foci of necrosis have been observed in the liver of 50% of enzyme-induced rats treated with halothane." | 3.66 | Hepatic necrosis in rats following halothane administration: protective effect of diethyldithiocarbamate. ( Eade, OE; Lucas, K; Millward-Sadler, GH; Mitchell, J; Wright, R, 1980) |
"The effect of halothane anesthesia on myocardial necrosis resulting from coronary artery ligation was examined in 28 anesthetized mongrel dogs." | 3.66 | The effect of halothane anesthesia on myocardial necrosis, hemodynamic performance, and regional myocardial blood flow in dogs following coronary artery occlusion. ( Davis, RF; DeBoer, LW; Lowenstein, E; Maroko, PR; Rude, RE, 1983) |
"Administration of anesthetic doses of halothane to hyperthyroid male rats results in the development of hepatic necrosis." | 3.66 | Characterization of hyperthyroidism enhancement of halothane-induced hepatotoxicity. ( Berman, ML; Harbison, RD; James, RC; Smith, AC, 1983) |
"Liver necrosis and an increase of serum sorbitol dehydrogenase activity can be produced in rats by halothane anesthesia (1% v/v in oxygen) following pretreatment with polychlorinated biphenyls." | 3.66 | [Prevention by metyrapone of halothane induced liver necrosis in rats (author's transl)]. ( Krüger, R; Nastainczyk, W; Rendic, S; Ullrich, V, 1982) |
"Exposure of phenobarbital-pretreated male Sprague-Dawley rats to halothane, 1 per cent, for two hours under conditions of hypoxia (FIO2 0." | 3.66 | An animal model of halothane hepatotoxicity: roles of enzyme induction and hypoxia. ( Brown, BR; McLain, GE; Sipes, IG, 1979) |
"Hepatic centrilobular necrosis developed in rats pretreated with triiodothyronine (T3) and then anesthetized with halothane, 1 per cent, for two hours at an ambient oxygen concentration." | 3.66 | Halothane-induced hepatic necrosis in triiodothyronine-pretreated rats. ( Berman, ML; Harbison, RD; Hoyle, P; Phythyon, JM; Wood, AJ; Wood, M, 1980) |
"8% enflurane, or 1% halothane in 21% oxygen (air) for two hours resulted in hepatic centrilobular necrosis." | 3.66 | Isoflurane and enflurane-induced hepatic necrosis in triiodothyronine-pretreated rats. ( Berman, ML; Holaday, DA; Kuhnert, L; Phythyon, JM, 1983) |
"The aetiology of massive liver-cell necrosis which developed in 16 patients following halothane anaesthesia was investigated by means of new serological techniques." | 3.66 | Specific serological markers in the diagnosis of fulminant hepatic failure associated with halothane anaesthesia. ( Davis, M; Gimson, AE; Neuberger, J; Williams, R, 1983) |
"Hepatic necrosis was induced in rats by a single exposure to 1 per cent halothane in oxygen following pretreatment with a single dose of Aroclor 1254, a polychlorinated biphenyl." | 3.65 | An animal model of hepatotoxicity associated with halothane anesthesia. ( Brown, BR; Sipes, IG, 1976) |
"After long-term exhibition to halothane (up to 96 hours), centrolobular hepatic damage (fatty degeneration, necrobiosis and necrosis) developed in rats, proportionally to the number of anesthesias and shortening of the intervals." | 3.65 | [Liver-damaging action of halothane--an animal experiment study]. ( Barz, H; Wolf, R, 1975) |
"Eight pregnant Sprague-Dawley rates were exposed to 10 ppm halothane 8 hours/day and 5 days/week throughout pregnancy." | 3.65 | Ultrastructural evidence of the hepatotoxic effect of halothane in rats following in-utero exposure. ( Chang, LW; Dudley, AW; Katz, J; Lee, YK, 1975) |
"Extensive infarction of the liver, initially thought to be halothane hepatitis, is described." | 3.65 | Spontaneous hepatic artery thrombosis with infarction of the liver. ( Balint, JA; Buhac, I; OConnor, PJ, 1976) |
"Analysis of data derived from 130 reports of jaundice occurring after anaesthesia with halothane showed a significant relation between the number of exposures to this anaesthetic and the rapidity with which jaundice develops after exposure." | 3.65 | Jaundice after repeated exposure to halothane: an analysis of Reports to the Committee on Safety of Medicines. ( Inman, WH; Mushin, WW, 1974) |
"The chloroform-treated rats also developed renal tubular necrosis with large increases in plasma creatinine and urea nitrogen, which were completely ameliorated by DMSO." | 1.30 | Late dimethyl sulfoxide administration provides a protective action against chemically induced injury in both the liver and the kidney. ( Gandolfi, AJ; Lind, RC, 1997) |
"Four groups received sham head trauma (surgical incision of the scalp but no trauma) and were treated with (A) nothing, (B) chronic ethanol (6% ethanol in drinking water for 40 days), (C) acute ethanol 1." | 1.30 | The influence of acute and chronic alcohol treatment on brain edema, cerebral infarct volume and neurological outcome following experimental head trauma in rats. ( Artru, AA; Donato, T; Lam, AM; Laohaprasit, V; Paez, A; Shapira, Y, 1997) |
"Hepatic necrosis was also seen after halothane anesthesia even at ambient oxygen concentrations, although the degree of necrosis was much milder." | 1.27 | Potentiation of halothane hepatotoxicity by chronic ethanol administration in rat: an animal model of halothane hepatitis. ( Ebihara, Y; Ishii, H; Kato, S; Nagata, S; Okuno, F; Takagi, T; Takahashi, H; Tashiro, M; Tsuchiya, M; Yamauchi, H, 1983) |
"5 or 23 mmol/kg) and sacrificed 24 h after dosing exhibited liver toxicity." | 1.26 | A study of the mechanism of halothane-induced liver necrosis. Role of covalent binding of halothane metabolites to liver proteins in the rat. ( Rao, GS, 1977) |
"The evidence suggests that acute pancreatitis may at times complicate viral hepatitis." | 1.25 | The association of viral hepatitis and acute pancreatitis. ( Geokas, MC; Olsen, H; Rinderknecht, H; Swanson, V, 1972) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 136 (91.28) | 18.7374 |
1990's | 11 (7.38) | 18.2507 |
2000's | 2 (1.34) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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CHADWICK, DA | 1 |
JENNINGS, RC | 1 |
SLATER, EM | 1 |
GIBSON, JM | 1 |
DYKES, MH | 2 |
WALZER, SG | 1 |
MINUCK, M | 1 |
SHERLOCK, S | 1 |
GREEN, KG | 1 |
MUNGAVIN, JM | 1 |
AFFOLTER, H | 1 |
HARTMANN, G | 1 |
KAPFHAMMER, V | 1 |
SCHEIDEGGER, S | 1 |
BALESTRA, L | 1 |
GIARDINA, B | 1 |
URSO, L | 1 |
DALMONTE, PR | 1 |
BRESCHI, F | 1 |
TURA, S | 1 |
GINGRICH, TF | 1 |
VIRTUE, RW | 1 |
HILSCHER, A | 1 |
Kumar, GP | 1 |
Bhat, VJ | 1 |
Sowdi, V | 1 |
Yu, WF | 1 |
Yang, LQ | 1 |
Zhou, MT | 1 |
Liu, ZQ | 1 |
Li, Q | 1 |
Babior, BM | 1 |
Davidson, CS | 2 |
Wibert, L | 1 |
Creutzfeldt, W | 1 |
Eger, W | 1 |
Nassr-Esfahani, H | 1 |
Eade, OE | 2 |
Millward-Sadler, GH | 1 |
Lucas, K | 1 |
Mitchell, J | 1 |
Wright, R | 2 |
Black, M | 1 |
Sinclair, M | 1 |
Venning, GR | 1 |
Plummer, JL | 2 |
Hall, PD | 4 |
Cousins, MJ | 5 |
Bastin, FN | 1 |
Ilsley, AH | 1 |
Davis, RF | 1 |
DeBoer, LW | 1 |
Rude, RE | 1 |
Lowenstein, E | 1 |
Maroko, PR | 1 |
Smith, AC | 2 |
Berman, ML | 3 |
James, RC | 1 |
Harbison, RD | 2 |
Takagi, T | 1 |
Ishii, H | 1 |
Takahashi, H | 1 |
Kato, S | 1 |
Okuno, F | 1 |
Ebihara, Y | 1 |
Yamauchi, H | 1 |
Nagata, S | 1 |
Tashiro, M | 1 |
Tsuchiya, M | 1 |
Gaunt, PS | 1 |
Meuten, DJ | 1 |
Pecquet-Goad, ME | 1 |
Nastainczyk, W | 1 |
Rendic, S | 1 |
Ullrich, V | 1 |
Krüger, R | 1 |
Neuberger, J | 3 |
Gimson, AE | 2 |
Davis, M | 2 |
Williams, R | 6 |
Kuhnert, L | 1 |
Phythyon, JM | 2 |
Holaday, DA | 1 |
Lewis, JH | 1 |
Zimmerman, HJ | 3 |
Ishak, KG | 1 |
Mullick, FG | 1 |
Knights, KM | 2 |
Gourlay, GK | 2 |
Hall, P | 1 |
Maddrey, WC | 2 |
Pohl, LR | 1 |
Gillette, JR | 1 |
Van Dyke, RA | 1 |
Wyke, RJ | 1 |
Canalese, JC | 1 |
Bauer, G | 1 |
Heidenreich, A | 1 |
Findor, J | 1 |
Bruch, E | 1 |
Schmee, E | 1 |
de Elizalde, S | 1 |
Ferraina, P | 1 |
Morel, C | 1 |
Mieli-Vergani, G | 1 |
Tredger, JM | 1 |
Friend, SC | 1 |
Wood, M | 1 |
Hoyle, P | 1 |
Wood, AJ | 1 |
Groom, S | 1 |
Checkley, S | 1 |
Crawford, B | 1 |
Lind, RC | 4 |
Gandolfi, AJ | 4 |
Hall, PM | 2 |
Farrell, GC | 2 |
Frost, L | 2 |
Tapner, M | 1 |
Field, J | 1 |
Weltman, M | 1 |
Mahoney, J | 2 |
Shapira, Y | 1 |
Lam, AM | 1 |
Paez, A | 1 |
Artru, AA | 1 |
Laohaprasit, V | 1 |
Donato, T | 1 |
Mezin, P | 1 |
Payen, JF | 1 |
Bosson, JL | 1 |
Brambilla, E | 1 |
Stieglitz, P | 1 |
Fukunaga, T | 1 |
Davies, P | 1 |
Zhang, L | 1 |
Hashida, Y | 1 |
Motoyama, EK | 1 |
Chisholm, M | 1 |
Hawksley, M | 1 |
Lloyd, B | 1 |
Moles, TM | 1 |
Edwards, JC | 1 |
GArdner, MJ | 1 |
Trowell, J | 1 |
Peto, R | 1 |
Mitchell, JR | 1 |
Potter, WZ | 1 |
Rao, GS | 2 |
Grumley, JO | 1 |
Boitnott, JK | 1 |
McLain, GE | 1 |
Sipes, IG | 2 |
Brown, BR | 2 |
Ross, WT | 1 |
Daggy, BP | 1 |
Cardell, RR | 1 |
Mazzia, VD | 1 |
Simon, AH | 1 |
Wills, EJ | 1 |
Walton, B | 2 |
Talbot, IC | 1 |
Gopinath, G | 1 |
Ford, EJ | 3 |
Wolf, R | 1 |
Barz, H | 1 |
Chang, LW | 2 |
Lee, YK | 2 |
Dudley, AW | 2 |
Katz, J | 2 |
Brase, A | 1 |
Emminger, E | 1 |
Bockslaff, H | 1 |
Bianchi, L | 1 |
De Groote, J | 1 |
Desmet, V | 1 |
Gedigk, P | 1 |
Korb, G | 1 |
Popper, H | 2 |
Poulsen, H | 1 |
Scheuer, PJ | 1 |
Schmid, M | 1 |
Thaler, H | 1 |
Wepler, W | 1 |
Sadove, MS | 1 |
Thomason, R | 1 |
Redlin, TA | 1 |
Katz, D | 1 |
OConnor, PJ | 1 |
Buhac, I | 1 |
Balint, JA | 1 |
Bird, GL | 1 |
Agardh, CD | 1 |
Smith, ML | 1 |
Siesjö, BK | 1 |
Lunam, CA | 1 |
Seki, S | 1 |
Mizoguchi, Y | 1 |
Saito, S | 1 |
Shiomi, S | 1 |
Sakagami, Y | 1 |
Sakaguchi, H | 1 |
Kuroki, T | 1 |
Harihara, S | 1 |
Kobayashi, K | 1 |
Monna, T | 1 |
Bilous, M | 1 |
Gibson, RA | 1 |
Roschlau, G | 1 |
Lumb, WV | 1 |
Grandy, JL | 1 |
Heath, RB | 1 |
Dunlop, CI | 1 |
Hodgson, DS | 1 |
Jong, HJ | 1 |
Ho, ST | 1 |
Wong, CS | 1 |
Hsu, JC | 1 |
Chang, CL | 1 |
Jenner, MA | 1 |
O'Brien, TD | 1 |
Raffe, MR | 1 |
Cox, VS | 1 |
Stevens, DL | 1 |
O'Leary, TP | 1 |
Grøntved, A | 1 |
Eriksen, S | 1 |
Gaba, DM | 1 |
Metz, S | 1 |
Maze, M | 1 |
Schmidt, G | 1 |
Börsch, G | 1 |
Ricken, D | 1 |
Müller, KM | 1 |
Gopinath, C | 2 |
Jones, RS | 2 |
Klinge, O | 1 |
Smith, JS | 1 |
Harrison, GG | 1 |
Mathieu, A | 1 |
DiPadua, D | 1 |
Mills, J | 1 |
Kahan, B | 1 |
Brierley, JB | 1 |
Miller, AA | 1 |
Sundell, B | 1 |
Brander, P | 1 |
Tammisto, T | 1 |
Naccarato, R | 1 |
Gritti, G | 1 |
Giunta, F | 1 |
Chiaramonte, M | 1 |
Valenti, F | 1 |
Leinweber, B | 1 |
Cüppers, M | 1 |
L'Allemand, H | 1 |
Gilbert, JP | 1 |
McPeek, B | 1 |
Gottlieb, LS | 1 |
Trey, C | 1 |
LaMont, JT | 1 |
McCaughey, W | 1 |
Clark, RB | 1 |
Jones, GL | 1 |
Greifenstein, FE | 1 |
Gardiol, D | 1 |
Lepore, MJ | 1 |
Qizilbash, AH | 1 |
Barth, ML | 1 |
Cornish, HH | 1 |
Simpson, BR | 2 |
Strunin, L | 2 |
Waalton, B | 1 |
Schatzki, PF | 1 |
Kay, S | 1 |
McGavic, JD | 1 |
Goertz, J | 1 |
Burnell, JM | 1 |
Runge, C | 1 |
Saunders, FC | 1 |
Thomas, ED | 1 |
Volwiler, W | 1 |
Nesvetov, AM | 1 |
Dovgiĭ, GM | 1 |
L'vova, TN | 1 |
Hussey, HH | 1 |
Inman, WH | 1 |
Mushin, WW | 1 |
Belcher, HV | 1 |
Remsberg, JR | 1 |
Cohen, EN | 1 |
Stenram, U | 1 |
Amstutz, HC | 1 |
Lurie, L | 1 |
Bullough, P | 1 |
Davis, JE | 1 |
Stenger, RJ | 1 |
Johnson, EA | 1 |
Geokas, MC | 1 |
Olsen, H | 1 |
Swanson, V | 1 |
Rinderknecht, H | 1 |
Owen, DR | 1 |
Schenken, JR | 1 |
Caravati, CM | 1 |
Hooker, TH | 1 |
Lempinen, M | 1 |
Collan, Y | 1 |
Sivula, A | 1 |
Merikallio, E | 1 |
Salmenkivi, K | 1 |
Paloheimo, M | 1 |
Turunen, MT | 1 |
Jokinen, EJ | 1 |
Ahlqvist, J | 1 |
Berglund, A | 1 |
Satler, J | 1 |
Voncina, J | 1 |
Lippman, PA | 1 |
Rivera, RA | 1 |
McAllister, HA | 1 |
Robinowitz, M | 1 |
Peters, RL | 1 |
Edmondson, HA | 1 |
Reynolds, TB | 1 |
Meister, JC | 1 |
Curpey, TJ | 1 |
Mäkelä, V | 1 |
Lähdesmäki, M | 1 |
Bog-Jensen, R | 1 |
Hansen, V | 1 |
Dordal, E | 1 |
Glagov, S | 1 |
Orlando, RA | 1 |
Platz, C | 1 |
Clauberg, G | 1 |
Schwesinger, G | 1 |
Pink, V | 1 |
Braune, R | 1 |
Celary, W | 1 |
Dentan, M | 1 |
Desmonts, JM | 1 |
Berthelot, P | 1 |
Robles, C | 1 |
Kelley, J | 1 |
Miller, RE | 1 |
Gronert, GA | 1 |
Schaner, PJ | 1 |
Gunther, RC | 1 |
Combes, B | 1 |
Lande, M | 1 |
Clot, C | 1 |
Vos, AK | 1 |
Neal, MJ | 1 |
Robson, JM | 1 |
DeBacker, LJ | 1 |
Longnecker, DS | 1 |
Babior, B | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Implication of Patient in the Making Ready of Recommendations for the Antivitamin K's Gestion in Case of Thrombosis Embolic Venous's Illness. Randomised Study for Clinical Validation.[NCT00227097] | 300 participants | Observational | 2002-12-31 | Terminated | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
11 reviews available for halothane and Necrosis
Article | Year |
---|---|
Drug induced liver disease.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Halothane; Humans; Liver; Necrosis | 1983 |
Drug-related acute and chronic hepatitis.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Hypersen | 1980 |
Drug metabolism in the production of liver injury.
Topics: Acetaminophen; Acetanilides; Alkylating Agents; Bromobenzenes; Chemical and Drug Induced Liver Injur | 1975 |
Drug-induced chronic hepatitis and cirrhosis.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adve | 1979 |
Acute liver injury.
Topics: Acetaminophen; Acute Disease; Chemical and Drug Induced Liver Injury; Cholestasis; Halothane; Hepati | 1975 |
Anaesthesia-related liver disease.
Topics: Anesthetics; Animals; Chemical and Drug Induced Liver Injury; Enflurane; Halothane; Humans; Incidenc | 1992 |
[30 years of halothane--30 years of halothane hepatitis].
Topics: Adult; Anesthesia, General; Chemical and Drug Induced Liver Injury; Child; Female; Halothane; Humans | 1987 |
Halothane in the United States. An appraisal of the literature on "halothane hepatitis" and the American reaction to it.
Topics: Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Drug Hypers | 1972 |
The effects of fluorinated anesthetics on the liver and kidneys.
Topics: Acute Kidney Injury; Adult; Anesthesia, Inhalation; Animals; Biotransformation; Chemical and Drug In | 1974 |
Postoperative juandice.
Topics: Aminosalicylic Acids; Anemia, Hemolytic; Bile Ducts; Bilirubin; Chemical and Drug Induced Liver Inju | 1974 |
The halothane dilemma: a case for the defence.
Topics: Adult; Anesthesia, General; Antigens; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; | 1971 |
4 trials available for halothane and Necrosis
Article | Year |
---|---|
Controlled prospective study of the effect on liver function of multiple exposures to halothane.
Topics: Aged; Alanine Transaminase; Anesthesia, Inhalation; Anesthetics; Aspartate Aminotransferases; Biopsy | 1975 |
Controlled trial of repeated halothane anaesthetics in patients with carcinoma of the uterine cervix treated with radium.
Topics: Adult; Aged; Alanine Transaminase; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; C | 1975 |
Prospective and retrospective searches for liver necrosis following halothane anesthesia. Serum enzyme study and case report.
Topics: Adult; Anesthesia, General; Chemical and Drug Induced Liver Injury; Clinical Enzyme Tests; Halothane | 1966 |
Summary of the national Halothane Study. Possible association between halothane anesthesia and postoperative hepatic necrosis.
Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Barbiturates; Cyclopropanes; Ethers; Female; Haloth | 1966 |
134 other studies available for halothane and Necrosis
Article | Year |
---|---|
MASSIVE HEPATIC NECROSIS ASSOCIATED WITH HALOTHANE ANESTHESIA.
Topics: Anesthesia; Atropine; Barbiturates; Chemical and Drug Induced Liver Injury; Colonic Neoplasms; Halot | 1964 |
POSTOPERATIVE HEPATIC NECROSIS. ITS INCIDENCE AND DIAGNOSTIC VALUE IN ASSOCIATION WITH THE ADMINISTRATION OF HALOTHANE.
Topics: Chemical and Drug Induced Liver Injury; Cyclopropanes; Diagnosis, Differential; Geriatrics; Halothan | 1964 |
MASSIVE HEPATIC NECROSIS ASSOCIATED WITH HALOTHANE ANAESTHESIA.
Topics: Anesthesia; Chemical and Drug Induced Liver Injury; Halothane; Hepatitis; Massive Hepatic Necrosis; | 1964 |
HALOTHANE AND THE LIVER.
Topics: Chemical and Drug Induced Liver Injury; Chloroform; Halothane; Hepatitis; Jaundice; Liver Diseases; | 1964 |
HALOTHANE AND THE LIVER: RETROSPECTIVE STUDIES.
Topics: Chemical and Drug Induced Liver Injury; Halothane; Hepatitis A; Liver Diseases; Necrosis; Retrospect | 1964 |
[ACUTE MASSIVE NECROSIS OF THE LIVER AFTER REPEATED HALOTHANE ANESTHESIA].
Topics: Anesthesia; Chemical and Drug Induced Liver Injury; Halothane; Hepatitis A; Necrosis; Pharmacology; | 1964 |
[COMPARATIVE EXPERIMENTAL STUDY OF THE HISTOLOGICAL CHANGES IN THE LIVER AND KIDNEY IN ACUTE POISONING BY CHLOROFORM, FLUOTHANE AND METHOCYFLURANE].
Topics: Anesthetics; Chemical and Drug Induced Liver Injury; Chloroform; Halothane; Hepatitis; Kidney; Kidne | 1964 |
[FUNCTIONAL AND BIOPTIC STUDY OF THE LIVER IN PATIENTS EXPOSED TO FLUOTHANE ANESTHESIA].
Topics: Alanine Transaminase; Alkaline Phosphatase; Anesthesia; Aspartate Aminotransferases; Chemical and Dr | 1964 |
POSTOPERATIVE LIVER DAMAGE: IS ANESTHESIA INVOLVED?
Topics: Anesthesia; Anesthetics; Chemical and Drug Induced Liver Injury; Geriatrics; Halogens; Halothane; He | 1965 |
[ONCE AGAIN: ACUTE MASSIVE NECROSIS OF THE LIVER AFTER HALOTHANE ANESTHESIA].
Topics: Anesthesia; Halothane; Liver Diseases; Necrosis; Toxicology | 1965 |
Fulminant hepatic failure following halothane anaesthesia.
Topics: Acute Kidney Injury; Adult; Anesthetics, Inhalation; Forensic Pathology; Halothane; Hand Injuries; H | 2005 |
Ca2+ cytochemical changes of hepatotoxicity caused by halothane and sevoflurane in enzyme-induced hypoxic rats.
Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Calcium; Chemical and Drug Induced Liver Inj | 2005 |
Postoperative massive liver necrosis. A clinical and pathological study.
Topics: Cardiovascular Diseases; Halothane; Hepatitis; Humans; In Vitro Techniques; Liver Diseases; Necrosis | 1967 |
[Recurrent jaundice with fatal liver necrosis after halothane anesthesia performances].
Topics: Anesthesia, General; Gastrectomy; Halothane; Humans; Jaundice; Liver Diseases; Male; Middle Aged; Ne | 1967 |
[Fluothane damage of the stressed liver].
Topics: Alcohols; Anesthesia; Animals; Chemical and Drug Induced Liver Injury; Halothane; Liver; Male; Necro | 1967 |
Hepatic necrosis in rats following halothane administration: protective effect of diethyldithiocarbamate.
Topics: Anesthesia, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Ditiocarb; Halothane; Liver | 1980 |
Does halothane cause liver necrosis.
Topics: Chemical and Drug Induced Liver Injury; Halothane; Humans; Liver; Necrosis | 1983 |
Does halothane cause liver necrosis?
Topics: Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Halothane; Humans; Necrosis | 1983 |
Hepatic injury in rats due to prolonged sub-anaesthetic halothane exposure.
Topics: Aerosols; Alanine Transaminase; Animals; Body Weight; Female; Halothane; Liver; Liver Regeneration; | 1983 |
The effect of halothane anesthesia on myocardial necrosis, hemodynamic performance, and regional myocardial blood flow in dogs following coronary artery occlusion.
Topics: Anesthesia, Inhalation; Animals; Coronary Circulation; Coronary Disease; Dogs; Female; Halothane; He | 1983 |
Characterization of hyperthyroidism enhancement of halothane-induced hepatotoxicity.
Topics: Alanine Transaminase; Animals; Biotransformation; Bromobenzenes; Chemical and Drug Induced Liver Inj | 1983 |
Potentiation of halothane hepatotoxicity by chronic ethanol administration in rat: an animal model of halothane hepatitis.
Topics: Alcoholism; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Synergism; | 1983 |
Hepatic necrosis associated with use of halothane in a dog.
Topics: Anesthesia, General; Animals; Chemical and Drug Induced Liver Injury; Dog Diseases; Dogs; Halothane; | 1984 |
[Prevention by metyrapone of halothane induced liver necrosis in rats (author's transl)].
Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Halothane; L-Iditol | 1982 |
Specific serological markers in the diagnosis of fulminant hepatic failure associated with halothane anaesthesia.
Topics: Acute Disease; Adolescent; Adult; Aged; Anesthesia, Inhalation; Antibodies; Chemical and Drug Induce | 1983 |
Isoflurane and enflurane-induced hepatic necrosis in triiodothyronine-pretreated rats.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Eating; Enflurane; Halothane; Hyperthy | 1983 |
Enflurane hepatotoxicity. A clinicopathologic study of 24 cases.
Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Enflurane; Female; Halothane; Human | 1983 |
The predictive value of changes in antipyrine pharmacokinetics in halothane and paracetamol induced hepatic necrosis in rats.
Topics: Acetaminophen; Animals; Antipyrine; Chemical and Drug Induced Liver Injury; Half-Life; Halothane; Ki | 1983 |
A perspective on halothane-induced hepatotoxicity.
Topics: Animals; Chemical and Drug Induced Liver Injury; Halothane; Humans; Liver; Necrosis; Rats | 1982 |
Hepatic centrilobular necrosis in rats after exposure to halothane, enflurane, or isoflurane.
Topics: Animals; Chemical and Drug Induced Liver Injury; Enflurane; Glutathione; Halothane; Isoflurane; Live | 1982 |
Bacteraemia in patients with fulminant hepatic failure.
Topics: Acetaminophen; Adolescent; Adult; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; H | 1982 |
[Indication for halothane anesthesia].
Topics: Adult; Anesthesia, General; Chemical and Drug Induced Liver Injury; Ear, Middle; Halothane; Humans; | 1982 |
[Hepatic lesion caused by halogenated anesthetics].
Topics: Chemical and Drug Induced Liver Injury; Enflurane; Halothane; Humans; Liver; Male; Middle Aged; Necr | 1982 |
Oxidative metabolism of halothane in the production of altered hepatocyte membrane antigens in acute halothane-induced hepatic necrosis.
Topics: Animals; Antigens, Surface; Chemical and Drug Induced Liver Injury; Cytotoxicity, Immunologic; Femal | 1981 |
Postanesthetic myonecrosis in horses.
Topics: Anesthesia; Animals; Calcium Metabolism Disorders; Halothane; Horse Diseases; Horses; Male; Muscles; | 1981 |
Halothane-induced hepatic necrosis in triiodothyronine-pretreated rats.
Topics: Alanine Transaminase; Animals; Body Weight; Chemical and Drug Induced Liver Injury; Cytochrome P-450 | 1980 |
Hepatic necrosis associated with halothane anesthesia in an alpaca.
Topics: Anesthesia, Inhalation; Animals; Camelids, New World; Chemical and Drug Induced Liver Injury; Haloth | 1995 |
A model for fatal halothane hepatitis in the guinea pig.
Topics: Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glu | 1994 |
Halothane-induced liver injury in guinea-pigs: importance of cytochrome P450 enzyme activity and hepatic blood flow.
Topics: Animals; Arteries; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Fomepizole; Genetic Pred | 1996 |
Late dimethyl sulfoxide administration provides a protective action against chemically induced injury in both the liver and the kidney.
Topics: Administration, Inhalation; Administration, Oral; Alanine Transaminase; Allyl Compounds; Animals; Bi | 1997 |
The influence of acute and chronic alcohol treatment on brain edema, cerebral infarct volume and neurological outcome following experimental head trauma in rats.
Topics: Administration, Oral; Alcoholism; Anesthesia, General; Animals; Brain; Brain Edema; Cerebral Hemorrh | 1997 |
Histological support for the difference between malignant hyperthermia susceptible (MHS), equivocal (MHE) and negative (MHN) muscle biopsies.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Atrophy; Biopsy; Disease Susceptibility; Female; H | 1997 |
Prolonged high intermittent positive-pressure ventilation induces airway remodeling and reactivity in young rats.
Topics: Animals; Carbachol; Fibrosis; Halothane; Hyperoxia; In Vitro Techniques; Inflammation; Intermittent | 1998 |
Extrahepatic tissue distribution, covalent binding, and toxicity of halothane in control and phenobarbital-pretreated rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Halothane; Kidney; Liver; Lung; Male; Necrosis; Phe | 1978 |
An animal model of halothane hepatotoxicity: roles of enzyme induction and hypoxia.
Topics: Alanine Transaminase; Anesthesia, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Cytoc | 1979 |
Hepatic necrosis caused by halothane and hypoxia in phenobarbital-treated rats.
Topics: Anesthesia, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Sys | 1979 |
Liver failure associated with halothane.
Topics: Adult; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Drug Labeling; Female; Haloth | 1977 |
A morphologic study of unexplained hepatitis following halothane anesthesia.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum; Female; Halothane; Human | 1978 |
A study of the mechanism of halothane-induced liver necrosis. Role of covalent binding of halothane metabolites to liver proteins in the rat.
Topics: Alanine Transaminase; Animals; DNA; Drug Interactions; Halothane; In Vitro Techniques; Lipid Metabol | 1977 |
The influence of hepatic microsomal amidopyrine demethylase activity on halothane hepatotoxicity in the horse.
Topics: Aminopyrine N-Demethylase; Animals; Carbon Disulfide; Chemical and Drug Induced Liver Injury; Chlorp | 1976 |
An animal model of hepatotoxicity associated with halothane anesthesia.
Topics: Anesthesia, Inhalation; Animals; Aroclors; Biotransformation; Chemical and Drug Induced Liver Injury | 1976 |
[Liver-damaging action of halothane--an animal experiment study].
Topics: Animals; Bile Pigments; Cell Division; Chemical and Drug Induced Liver Injury; Dose-Response Relatio | 1975 |
Ultrastructural evidence of the hepatotoxic effect of halothane in rats following in-utero exposure.
Topics: Animals; Animals, Newborn; Chemical and Drug Induced Liver Injury; Cytoplasm; Environmental Pollutan | 1975 |
Liver disease caused by medicinal agents.
Topics: Adrenal Cortex Hormones; Analgesics; Chemical and Drug Induced Liver Injury; Cholestasis; Contracept | 1975 |
Halothane on irradiated liver tissue.
Topics: Acute Disease; Animals; Chronic Disease; Dose-Response Relationship, Drug; Dose-Response Relationshi | 1975 |
[Rules for the histological evaluation of drug-induced liver lesions].
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholestasis; Contraceptives, Oral; F | 1975 |
Postoperative fever and the halothane controversy.
Topics: Anesthesia, General; Chemical and Drug Induced Liver Injury; Fever; Halothane; Humans; Malignant Hyp | 1975 |
Spontaneous hepatic artery thrombosis with infarction of the liver.
Topics: Aged; Amputation, Surgical; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Diagnosi | 1976 |
Subanesthetic halothane is hepatotoxic in the guinea pig.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, D | 1992 |
The influence of hypothermia on hypoglycemia-induced brain damage in the rat.
Topics: Animals; Blood Glucose; Body Temperature; Brain; Brain Diseases; Halothane; Hypoglycemia; Hypothermi | 1992 |
Covalent binding of oxidative biotransformation intermediates is associated with halothane hepatotoxicity in guinea pigs.
Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Halothane; Lipid Metabolism; Liv | 1990 |
The pathology of halothane hepatotoxicity in a guinea-pig model: a comparison with human halothane hepatitis.
Topics: Alanine Transaminase; Anesthesia, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Disea | 1989 |
[A clinicopathological study of 11 patients with acute drug-induced hepatic failure].
Topics: Acute Disease; Adult; Aged; Chemical and Drug Induced Liver Injury; Ethionamide; Female; Halothane; | 1986 |
Altered hepatic calcium homeostasis in guinea pigs with halothane-induced hepatotoxicity.
Topics: Alanine Transaminase; Animals; Calcium; Cytochrome P-450 Enzyme System; Female; Guinea Pigs; Halotha | 1988 |
Halothane induced hepatic necrosis in rats: the role of in vivo lipid peroxidation.
Topics: Alanine Transaminase; Animals; Fatty Acids; Halothane; Lipid Metabolism; Lipid Peroxidation; Liver; | 1988 |
Clinical report, "Hepatic necrosis following halothane anesthesia in goats," viewed as unacceptable.
Topics: Animals; Chemical and Drug Induced Liver Injury; Goats; Halothane; Liver Diseases; Necrosis | 1987 |
[Unexplained fatal hepatic necrosis following halothane--a case report].
Topics: Aged; Anesthesia; Chemical and Drug Induced Liver Injury; Halothane; Humans; Male; Necrosis | 1987 |
Hepatic effects of repeated halothane anesthetics in the hypoxic rat model.
Topics: Anesthesia, Inhalation; Animals; Halothane; Hypoxia; Liver; Male; Necrosis; Rats; Rats, Inbred F344; | 1987 |
Hepatic necrosis following halothane anesthesia in goats.
Topics: Anesthesia, General; Animals; Female; Goats; Halothane; Liver; Necrosis | 1986 |
[Local anesthetics with added adrenaline during halothane anesthesia. Assessment of the risk of necrosis and systemic side effects when these preparations are employed peripherally].
Topics: Anesthesia, Inhalation; Anesthetics, Local; Epinephrine; Halothane; Humans; Lidocaine; Necrosis; Ris | 1987 |
Postcountershock myocardial damage after pretreatment with adrenergic and calcium channel antagonists in halothane-anesthetized dogs.
Topics: Anesthesia, Inhalation; Animals; Calcium Channel Blockers; Dogs; Electric Countershock; Female; Halo | 1985 |
[Centrolobular liver cell necroses following occupational halothane contact. Association with antibodies to halothane altered liver cell components].
Topics: Adult; Autoantibodies; Biopsy; Chemical and Drug Induced Liver Injury; Female; Halothane; Humans; Li | 1985 |
The effect of the repeated administration of halothane on the liver of the horse.
Topics: Adenosine Triphosphatases; Alcohol Oxidoreductases; Alkaline Phosphatase; Animals; Arginase; Asparta | 1970 |
[Morphology and etiology of halothane-induced liver lesions (author's transl)].
Topics: Adult; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Child; Cholestasis; Fatty Liv | 1972 |
The effects of multiple anaesthetics on the livers of rats subjected to microsomal enzyme induction. A preliminary report.
Topics: Anesthetics; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Enzyme | 1973 |
Experimental immunity to a metabolite of halothane and fluroxene: cutaneous delayed-type hypersensitivity.
Topics: Albumins; Animals; Biotransformation; Cattle; Chemical and Drug Induced Liver Injury; Disease Models | 1974 |
Fatal brain damage after dental anaesthesia. Its nature, etiology, and prevention.
Topics: Adult; Anesthesia, Dental; Anesthesia, Inhalation; Brain Diseases; Halothane; Humans; Male; Methohex | 1966 |
The effects of chloroform or halothane on horse liver in the early stage of ragwort poisoning.
Topics: Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Arginase; Bilirubin; Biopsy; Chemical and | 1972 |
Ultrastructural changes in the nervous system after chronic exposure to halothane.
Topics: Animals; Brain Diseases; Cerebral Cortex; Chronic Disease; Endoplasmic Reticulum; Environmental Expo | 1974 |
The spectrum of hepatotoxicity.
Topics: Aminosalicylic Acids; Anti-Bacterial Agents; Antimetabolites; Benzene Derivatives; Carbon Tetrachlor | 1968 |
Post-anesthetic tissue necrosis in experimental pedicle skin flaps.
Topics: Acid-Base Equilibrium; Anesthetics; Animals; Blood Volume; Central Venous Pressure; Ethers; Graft vs | 1969 |
Letter: Hepatic necrosis after enflurance anesthesia.
Topics: Anesthesia; Chemical and Drug Induced Liver Injury; Female; Halothane; Humans; Hydrocarbons, Halogen | 1974 |
[Exchange transfusion in the treatment of acute hepatic insufficiency].
Topics: Acute Disease; Adolescent; Adult; Child; Child, Preschool; Exchange Transfusion, Whole Blood; Fatty | 1974 |
Editorial: Halothane and liver damage.
Topics: Anesthetics; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Halothane; Humans; Jaund | 1974 |
Morphological results of the rat liver after the application of halothane and hypoxia.
Topics: Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cholinesterases; Endop | 1974 |
Halothane metabolism and the liver.
Topics: Anesthesia, General; Chemical and Drug Induced Liver Injury; Halothane; Humans; Liver; Necrosis; Ret | 1973 |
A summary of the National Halothane Study.
Topics: Chemical and Drug Induced Liver Injury; Halothane; Humans; Necrosis; United States | 1972 |
Anesthesia and hepatic necrosis.
Topics: Anesthetics; Chemical and Drug Induced Liver Injury; Cyclopropanes; Halothane; Humans; Necrosis | 1972 |
[Early postoperative jaundice and peroperative liver diseases. Point of view of the anatomo-pathologist].
Topics: Anesthesia; Animals; Chemical and Drug Induced Liver Injury; Dogs; Halothane; Jaundice; Liver; Necro | 1972 |
Fulminant hepatic failure.
Topics: Adolescent; Adult; Age Factors; Aged; Enzymes; Exchange Transfusion, Whole Blood; Halothane; Hepatic | 1973 |
Halothane hepatitis.
Topics: Adult; Alkaline Phosphatase; Anesthesia, Inhalation; Aspartate Aminotransferases; Autopsy; Bilirubin | 1973 |
The absence of effect of phenobarbital on halothane toxicity.
Topics: Aerosols; Animals; Aspartate Aminotransferases; Body Weight; Halothane; Kidney; L-Lactate Dehydrogen | 1973 |
Halothane hepatitis--fact or fallacy.
Topics: Antibodies; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Drug Hypersensitivity; | 1973 |
Ultrastructural pathology of a case of halothane hepatitis.
Topics: Adult; Chemical and Drug Induced Liver Injury; Halothane; Humans; Kupffer Cells; Liver; Male; Micros | 1973 |
Histological appearances in fulminant hepatic failure with reference to aetiology, time of survival and role of immunological processes.
Topics: Acetaminophen; Adolescent; Adult; Aged; Cell Nucleus; Chemical and Drug Induced Liver Injury; Haloth | 1973 |
Acute hepatic failure treated by cross circulation.
Topics: Acute Disease; Adult; Anesthesia; Aspartate Aminotransferases; Bilirubin; Blood Donors; Blood Platel | 1973 |
[Malignant hyperthermia during anesthesia].
Topics: Adult; Anesthesia, Endotracheal; Animals; Autopsy; Brain Edema; Chick Embryo; Halothane; Hand; Heart | 1973 |
Editorial: Fulminant hepatic failure.
Topics: Age Factors; Aged; Anesthesia; Calcium; Chemical and Drug Induced Liver Injury; Exchange Transfusion | 1973 |
Jaundice after repeated exposure to halothane: an analysis of Reports to the Committee on Safety of Medicines.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Anesthesia, Inhalation; England; Female; Haloth | 1974 |
Halothane anesthesia, hepatic necrosis, and death: report of a case.
Topics: Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Female; Halothane; Humans; Middle Ag | 1967 |
The biotransformation of halothane.
Topics: Animals; Autoradiography; Biotransformation; Carbon Isotopes; Chemical and Drug Induced Liver Injury | 1971 |
Fatal hepatic necrosis and halothane.
Topics: Chemical and Drug Induced Liver Injury; Female; Halothane; Humans; Middle Aged; Necrosis | 1972 |
Skeletal fixation with self-curing polymethyl methacrylate. A report of 23 canine total hip replacements.
Topics: Acetabulum; Acrylic Resins; Anesthesia, Inhalation; Animals; Bone Development; Bone Resorption; Dogs | 1972 |
Fatal hepatic necrosis associated with halothane anesthesia.
Topics: Adult; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Female; Halothane; Hepatitis; | 1972 |
Effects of phenobarbital pretreatment on the response of rat liver to halothane administration.
Topics: Anesthesia, General; Animals; Chemical and Drug Induced Liver Injury; Cytochromes; Enzyme Induction; | 1972 |
The association of viral hepatitis and acute pancreatitis.
Topics: Adult; Aged; Autolysis; Autopsy; Child, Preschool; Female; Halothane; Hepatitis A; Humans; Liver Dis | 1972 |
Halothane hepatitis--an unsettled issue.
Topics: Aged; Chemical and Drug Induced Liver Injury; Female; Halothane; Humans; Male; Middle Aged; Necrosis | 1972 |
Halothane hepatitis.
Topics: Chemical and Drug Induced Liver Injury; Halothane; Hepatitis A; Humans; Necrosis | 1971 |
Acute massive hepatic necrosis with fatal liver failure.
Topics: Acute Disease; Adolescent; Adult; Aged; Anticonvulsants; Antitubercular Agents; Azathioprine; Blood | 1971 |
Pig-liver perfusion. Extracorporeal pig-liver perfusion in a patient with acute hepatic failure.
Topics: Adult; Ammonia; Anesthesia, Inhalation; Animals; Autopsy; Bilirubin; Biopsy; Embolism; Female; Halot | 1971 |
[Jaundice after halothane anesthesia].
Topics: Adult; Anesthesia; Aspartate Aminotransferases; Bilirubin; Body Temperature; Chemical and Drug Induc | 1971 |
Fatal liver necrosis after repeated halothane anesthesia.
Topics: Anesthesia; Chemical and Drug Induced Liver Injury; Halothane; Humans; Intestinal Obstruction; Middl | 1971 |
Halothane anesthesia and postoperative liver necrosis.
Topics: Anesthesia, General; Chemical and Drug Induced Liver Injury; Cholecystectomy; Female; Halothane; Hum | 1968 |
Fulminant hepatic necrosis following halothane anesthesia.
Topics: Acute Disease; Chemical and Drug Induced Liver Injury; Female; Halothane; Humans; Middle Aged; Necro | 1970 |
Hepatic necrosis associated with halothane anesthesia.
Topics: Anesthesia; Autopsy; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis; Collagen; Connecti | 1969 |
Haemobilia associated with hepatic necrosis after halothane anaesthesia. A case report.
Topics: Anesthesia, Inhalation; Biliary Tract; Chemical and Drug Induced Liver Injury; Halothane; Hemorrhage | 1969 |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 10-1970.
Topics: Aged; Autopsy; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Female; Halothane; H | 1970 |
[Liver necrosis after halothane anesthesia].
Topics: Anesthesia, Inhalation; Halothane; Humans; Liver; Male; Middle Aged; Necrosis | 1970 |
Liver necrosis after repeated fluothane anaesthesia. Cause or coincidence?
Topics: Adolescent; Aged; Anesthesia, General; Biopsy; Chemical and Drug Induced Liver Injury; Female; Halot | 1970 |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 24-1970.
Topics: Aged; Autopsy; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Diagnosis, Diffe | 1970 |
Fatal halothane hepatitis with transient granulomas.
Topics: Adult; Anesthesia, Inhalation; Autopsy; Biopsy; Chemical and Drug Induced Liver Injury; Drug Hyperse | 1970 |
[Studies of the effect of an inhalation anesthesia and surgery on the liver function with special reference to halothane. 1].
Topics: Alanine Transaminase; Anesthesia, Inhalation; Animals; Aspartate Aminotransferases; Bilirubin; Chemi | 1970 |
[Postoperative toxic liver disease].
Topics: Aged; Autopsy; Chemical and Drug Induced Liver Injury; Cholecystectomy; Cholelithiasis; Female; Halo | 1971 |
[Halothane hepatitis].
Topics: Chemical and Drug Induced Liver Injury; Female; Halothane; Humans; Hypersensitivity, Delayed; Liver; | 1971 |
[Halothane and hepatic necrosis].
Topics: Adult; Anesthesia, Endotracheal; Halothane; Humans; Liver Diseases; Male; Necrosis | 1967 |
Halothane and liver injury.
Topics: Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Halothane; Humans; Liver; Liver Dise | 1968 |
Hepatic necrosis following halothane anesthesia.
Topics: Chemical and Drug Induced Liver Injury; Female; Halothane; Humans; Necrosis | 1968 |
Massive hepatic necrosis following multiple exposures to halothane.
Topics: Aged; Brain; Diagnosis, Differential; Female; Halothane; Hemorrhage; Humans; Kidney; Kidney Diseases | 1968 |
Multiple halothane anesthesia in the burn patient.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Anesthesia, Inhalation; Aspartate Aminotransferases; | 1968 |
Halothane-induced liver damage--an entity.
Topics: Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Halothane; Humans; Liver; Liver Disea | 1969 |
[Halothane and liver toxicity].
Topics: Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Chloroform; Fever; Halothane; Hepati | 1969 |
[Acute liver cell necrosis].
Topics: Adult; Barbiturates; Chemical and Drug Induced Liver Injury; Female; Halothane; Humans; Liver; Liver | 1969 |
The analgesic and anaesthetic actions of tetrafluorobenzene.
Topics: Analgesics; Anesthesia, Inhalation; Anesthetics; Animals; Arrhythmias, Cardiac; Benzene; Blood Press | 1966 |
Concerning hepatotoxicity of halothane.
Topics: Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Halothane; Humans; Necrosis | 1966 |