halothane has been researched along with Muscle Contraction in 507 studies
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Contracture responses of intact cut masseter and vastus bundles (non-skinned) do not differ with respect to caffeine and halothane." | 7.70 | Caffeine- or halothane-induced contractures of masseter muscle are similar to those of vastus muscle in normal humans. ( Antognini, JF; Gronert, GA; Melton, AT, 1999) |
| "The contractile activity, the threshold for calcium-induced calcium release in fractions of sarcoplasmic reticulum and the potassium concentration were determined in preparations of semimembranosus muscle from normal quarter horses and quarter horses with hyperkalaemic periodic paralysis before and after they were treated with phenytoin." | 7.69 | Effect of phenytoin on skeletal muscle from quarter horses with hyperkalaemic periodic paralysis. ( Beech, J; Dawso, T; Fletcher, JE; Lindborg, S; Tripolitis, L, 1995) |
| " We evaluated whether toxic concentrations of cocaine altered the in vitro muscle response to halothane during contracture tests for MH." | 7.69 | Effect of cocaine on the contracture response to 1% halothane in patients undergoing diagnostic muscle biopsy for malignant hyperthermia. ( Brum, JM; DeBoer, GE; Mitsumoto, H; Sato, N, 1995) |
| "Hypoxia and halothane are both known to have different effects on the release and disposition of norepinephrine at sympathetic nerve terminals during neurotransmission." | 7.68 | Altered release and metabolism of norepinephrine in superfused canine saphenous veins in the presence of halothane and hypoxia. ( Kamath, GS; Rorie, DK; Tyce, GM, 1993) |
| " Pressor dose-response curves to the selective alpha 1-adrenergic agonist, phenylephrine, were constructed in groups of rabbits before, during and 2 hr after halothane anesthesia and the dose of phenylephrine that induced a 25 torr increase in mean arterial pressure (ED25) was derived by polynomial regression analysis." | 7.67 | Prolonged hyporesponsiveness of vascular smooth muscle contraction after halothane anesthesia in rabbits. ( Hoffman, BB; Maze, M; Smith, CM; Spiss, CK; Tsujimoto, G, 1985) |
| "The in vitro halothane and caffeine contracture tests have been performed on muscle tissue from six survivors of the neuroleptic malignant syndrome." | 7.67 | Neuroleptic malignant syndrome and malignant hyperthermia. In vitro comparison with halothane and caffeine contracture tests. ( Adnet, P; Guevart, E; Krivosic-Horber, R; Lestavel, P; Theunynck, D, 1987) |
| "We evaluated six boys who had developed isolated masseter muscle spasm following intravenous succinylcholine." | 7.66 | Masseter spasm induced by succinylcholine in children: contracture testing for malignant hyperthermia: report of six cases. ( Flewellen, EH; Nelson, TE, 1982) |
| "Pretreatment with halothane significantly diminished carbachol-induced increases in [Ca2+]i by 77% and muscle tension by 83% in a dose-dependent manner." | 5.30 | Role of intracellular Ca2+ stores in the inhibitory effect of halothane on airway smooth muscle contraction. ( Kohro, S; Matsuzaki, T; Namiki, A; Tsuchida, H; Yamakage, M, 1998) |
| "Halothane is a potent bronchodilator." | 5.29 | Inhibitory effects of halothane on high(K+)-induced canine tracheal smooth muscle contraction and intracellular Ca2+ increment. ( Kawamata, T; Kohro, S; Namiki, A; Yamakage, M, 1994) |
| "In vitro, prospective, repeated-measures, dose-response study." | 5.29 | Effect of halothane on phenylephrine-induced vascular smooth muscle contractions in endotoxin-exposed rat aortic rings. ( Bina, S; Grissom, TE; Hart, J; Muldoon, SM, 1996) |
| "The association of malignant hyperthermia (MH) with neuromuscular disorders has been recognized since 1970." | 5.27 | Halothane-caffeine contracture testing in neuromuscular diseases. ( Fletcher, JE; Heiman-Patterson, TD; Rosenberg, H; Tahmoush, AJ, 1988) |
| "To investigate the relationship between total body weight (TBW) or body mass index (BMI) and atracurium reversal time." | 3.70 | Antagonism of atracurium-induced block in obese patients. ( Kirkegaard-Nielsen, H; Lindholm, P; Petersen, HS; Severinsen, IK, 1998) |
| " Neuromuscular blockade was induced and maintained with atracurium." | 3.70 | New equipment for neuromuscular transmission monitoring: a comparison of the TOF-Guard with the Myograph 2000. ( Helbo-Hansen, HS; Kirkegaard-Nielsen, H; Lindholm, P; Pedersen, HS; Schmidt, MB; Severinsen, IK, 1998) |
| "Contracture responses of intact cut masseter and vastus bundles (non-skinned) do not differ with respect to caffeine and halothane." | 3.70 | Caffeine- or halothane-induced contractures of masseter muscle are similar to those of vastus muscle in normal humans. ( Antognini, JF; Gronert, GA; Melton, AT, 1999) |
| "The contractile activity, the threshold for calcium-induced calcium release in fractions of sarcoplasmic reticulum and the potassium concentration were determined in preparations of semimembranosus muscle from normal quarter horses and quarter horses with hyperkalaemic periodic paralysis before and after they were treated with phenytoin." | 3.69 | Effect of phenytoin on skeletal muscle from quarter horses with hyperkalaemic periodic paralysis. ( Beech, J; Dawso, T; Fletcher, JE; Lindborg, S; Tripolitis, L, 1995) |
| " We evaluated whether toxic concentrations of cocaine altered the in vitro muscle response to halothane during contracture tests for MH." | 3.69 | Effect of cocaine on the contracture response to 1% halothane in patients undergoing diagnostic muscle biopsy for malignant hyperthermia. ( Brum, JM; DeBoer, GE; Mitsumoto, H; Sato, N, 1995) |
| "Hypoxia and halothane are both known to have different effects on the release and disposition of norepinephrine at sympathetic nerve terminals during neurotransmission." | 3.68 | Altered release and metabolism of norepinephrine in superfused canine saphenous veins in the presence of halothane and hypoxia. ( Kamath, GS; Rorie, DK; Tyce, GM, 1993) |
| " In vitro, human MHS muscle samples were exposed to propofol and changes in (a) baseline tension and (b) contracture tension on exposure to halothane and caffeine were measured." | 3.68 | Propofol is a 'safe' anaesthetic agent in malignant hyperthermia susceptible patients. ( Couchman, KG; McKenzie, AJ; Pollock, N, 1992) |
| "The in vitro contracture test determines the sensitivity of freshly obtained skeletal muscle specimens to caffeine or halothane applied to a bathing solution." | 3.68 | In vitro contracture testing for determination of susceptibility to malignant hyperthermia: a methodologic update. ( Gallagher, WJ; Iaizzo, PA; Wedel, DJ, 1991) |
| " When tetrodotoxin was given to block neural activity, the ACh response was unchanged, confirming that neural activation did not contribute significantly to smooth muscle contraction in response to ACh." | 3.68 | Direct and neurally mediated effects of halothane on pulmonary resistance in vivo. ( Brichant, JF; Rehder, K; Vettermann, J; Warner, DO, 1990) |
| " The in vitro halothane-caffeine contracture tests are the most reliable method of identifying individuals susceptible to MH." | 3.67 | The association between the neuroleptic malignant syndrome and malignant hyperthermia. ( Adamantidis, MM; Adnet, PJ; Adnet-Bonte, CA; Dupuis, BA; Haudecoeur, G; Krivosic-Horber, RM; Saulnier, F, 1989) |
| "08 mg/kg), 36 surgical patients undergoing barbiturate/halothane anesthesia were given edrophonium 0." | 3.67 | [Antagonism of an intubation dose of vecuronium]. ( Baar, H; Lazarus, G; Sold, M, 1987) |
| " Pressor dose-response curves to the selective alpha 1-adrenergic agonist, phenylephrine, were constructed in groups of rabbits before, during and 2 hr after halothane anesthesia and the dose of phenylephrine that induced a 25 torr increase in mean arterial pressure (ED25) was derived by polynomial regression analysis." | 3.67 | Prolonged hyporesponsiveness of vascular smooth muscle contraction after halothane anesthesia in rabbits. ( Hoffman, BB; Maze, M; Smith, CM; Spiss, CK; Tsujimoto, G, 1985) |
| "The in vitro halothane and caffeine contracture tests have been performed on muscle tissue from six survivors of the neuroleptic malignant syndrome." | 3.67 | Neuroleptic malignant syndrome and malignant hyperthermia. In vitro comparison with halothane and caffeine contracture tests. ( Adnet, P; Guevart, E; Krivosic-Horber, R; Lestavel, P; Theunynck, D, 1987) |
| "Seventy-seven patients who developed masseter muscle rigidity (MMR) after receiving succinylcholine to facilitate tracheal intubation were evaluated for malignant hyperthermia (MH) susceptibility by in vitro halothane and caffeine contracture tests." | 3.67 | Masseter muscle rigidity and malignant hyperthermia susceptibility. ( Fletcher, JE; Rosenberg, H, 1986) |
| "The mechanism underlying the decrease in minute ventilation (VE) observed under halothane anesthesia was investigated in nine spontaneously breathing dogs." | 3.67 | Effect of halothane on diaphragmatic muscle function in pentobarbital-anesthetized dogs. ( Aubier, M; Clergue, F; Lemesle, P; Pariente, R; Viars, P; Viires, N, 1986) |
| "Studies were conducted on the effects of isoflurane and halothane on intracellular mechanisms of striated muscle contraction: Ca2+ activation of the contractile proteins and Ca2+ uptake and release from the sarcoplasmic reticulum." | 3.67 | Intracellular mechanism of action of isoflurane and halothane on striated muscle of the rabbit. ( Bell, JG; Su, JY, 1986) |
| " Succinylcholine administration caused prolonged, severe muscle fasciculations followed by tachycardia, and an elevated blood pressure." | 3.67 | Unusual response following use of succinylcholine in a horse anesthetized with halothane. ( Hildebrand, SV; Riedesel, DH, 1985) |
| "We evaluated six boys who had developed isolated masseter muscle spasm following intravenous succinylcholine." | 3.66 | Masseter spasm induced by succinylcholine in children: contracture testing for malignant hyperthermia: report of six cases. ( Flewellen, EH; Nelson, TE, 1982) |
| "In a study of human malignant hyperpyrexia-susceptible muscle a comparison between pancuronium and methylprednisolone showed that both drugs produced qualitatively similar depression of the halothane-induced muscle contracture." | 3.65 | Anaesthesia for patients susceptible to malignant hyperpyrexia. A study of pancuronium and methylprednisolone. ( Cain, PA; Ellis, FR, 1977) |
| " Using muscle from patients susceptible to malignant hyperpyrexia in vitro, it has been demonstrated that muscle contracture can occur with procaine on its own, and in one patient the halothane-induced contracture was potentiated by procaine." | 3.65 | An evaluation of procaine in the treatment of malignant hyperpyrexia. ( Clarke, IM; Ellis, FR, 1975) |
| "Halothane-induced contractures in isolated muscle fibers from swine susceptible to malignant hyperthermia (MHS) were significantly less when fibers were incubated in KRB plus 6." | 3.65 | Porcine malignant hyperthermia: effect of dantrolene sodium on in-vitro halothane-induced contraction of susceptible muscle. ( Anderson, IL; Jones, EW, 1976) |
| " All other pharmacodynamic parameters were similar." | 2.67 | A comparison of the pharmacodynamics of rocuronium and vecuronium during halothane anaesthesia. ( Baird, WL; Booth, MG; Bryden, FM; Marsh, B; Robertson, EN, 1992) |
| "Mivacurium is a new short-acting competitive neuromuscular blocking agent." | 2.66 | Continuous infusion of mivacurium in children. ( Alifimoff, JK; Goudsouzian, NG, 1989) |
| "We were interested in determining the dose-response relationship of atracurium in children (2-10 yr) during nitrous oxide-isoflurane anesthesia (1%) and the atracurium infusion rate required to maintain about 95% neuromuscular blockade during nitrous oxide-halothane (0." | 2.66 | Atracurium infusion requirements in children during halothane, isoflurane, and narcotic anesthesia. ( Brandom, BW; Cook, DR; Fehr, B; Lineberry, CG; Rudd, GD; Woelfel, SK, 1985) |
| "Pancuronium 3 mg/70 kg was antagonized with neostigmine 2." | 2.65 | Impaired neostigmine antagonism of pancuronium during enflurane anaesthesia in man. ( Bevan, DR; Delisle, S, 1982) |
| "Malignant hyperthermia is a hypermetabolic syndrome that appears in susceptible patients after exposure to certain anaesthetic drugs (succinylcholine, inhalation anaesthetics)." | 2.55 | Clinical protocol for the management of malignant hyperthermia. ( Alsina, E; Del Blanco, B; Domínguez, A; García, A; Guerrero, JL; Kollmann-Camaiora, A; Yepes, MJ, 2017) |
| "The problem of malignant hyperthermia may become worse in the near future due to changes in the population brought about by immigration." | 2.44 | [Anesthesia in malignant hyperthermia]. ( Ortiz Gómez, JR, 2008) |
| "Most patients with malignant hyperthermia susceptibility diagnosed by the in vitro caffeine-halothane contracture test (CHCT) develop excessive force in response to halothane but not caffeine (halothane-hypersensitive)." | 1.91 | Distinct pathophysiological characteristics in developing muscle from patients susceptible to malignant hyperthermia. ( Figueroa, L; Ibarra-Moreno, CA; Kraeva, N; Manno, C; Riazi, S; Rios, E; Tammineni, ER, 2023) |
| "The variable clinical presentation of malignant hyperthermia (MH), a disorder of calcium signalling, hinders its diagnosis and management." | 1.51 | Abnormal calcium signalling and the caffeine-halothane contracture test. ( Figueroa, L; Kraeva, N; Manno, C; Riazi, S; Ríos, E; Toro, S, 2019) |
| "Hydrogen sulfide is an endogenous gasotransmitter and its mechanism of action involves activation of ATP-sensitive K(+) channels and phosphodiesterase inhibition." | 1.43 | Cystathionine β-synthase-derived hydrogen sulfide is involved in human malignant hyperthermia. ( Andria, B; Attanasio, C; Bucci, M; Calderone, V; Cantalupo, A; Cirino, G; Di Martino, A; Ianaro, A; Mancini, A; Panza, E; Savoia, G; Vellecco, V, 2016) |
| "Several malignant hyperthermia-associated neuromuscular diseases are associated with an altered connective tissue composition." | 1.40 | Contractile elements in muscular fascial tissue - implications for in-vitro contracture testing for malignant hyperthermia. ( Hoppe, K; Jäger, H; Klingler, W; Lehmann-Horn, F; Schleip, R, 2014) |
| "The clinical symptoms resemble malignant hyperthermia (MH), which may lead to mistreatment of the patient." | 1.39 | In vitro muscle contracture investigations on the malignant hyperthermia like episodes in myotonia congenita. ( Adolph, O; Chaiklieng, S; Hoppe, K; Jurkat-Rott, K; Klingler, W; Lehmann-Horn, F, 2013) |
| "Sevoflurane is a known triggering agent of malignant hyperthermia (MH)." | 1.39 | Sevoflurane is less sensitive than halothane for in vitro detection of malignant hyperthermia susceptibility. ( Heiderich, S; Johannsen, S; Klingler, W; Roewer, N; Schneiderbanger, D; Schuster, F, 2013) |
| "Halothane was the strongest discriminator for malignant hyperthermia in the in-vitro contracture tests." | 1.37 | In-vitro contracture testing for susceptibility to malignant hyperthermia: can halothane be replaced? ( Anetseder, M; Kranke, P; Metterlein, T; Roewer, N; Schuster, F, 2011) |
| "Halothane was discontinued after the administration of 0." | 1.37 | Comparison of the therapeutic effectiveness of a dantrolene sodium solution and a novel nanocrystalline suspension of dantrolene sodium in malignant hyperthermia normal and susceptible pigs. ( Becker, S; Burmester, S; Gerbershagen, MU; Kröner, L; Lenz, D; Schütte, JK; Starosse, A; Wappler, F, 2011) |
| "To diagnose malignant hyperthermia (MH) susceptibility, muscle bundles are exposed to halothane and caffeine." | 1.37 | Sevoflurane as a potential replacement for halothane in diagnostic testing for malignant hyperthermia susceptibility: results of a preliminary study. ( Anetseder, M; Hartung, E; Metterlein, T; Roewer, N; Schuster, F, 2011) |
| "We report the first case of malignant hyperthermia, verified by caffeine-halothane contracture test and genetic testing, in a Chinese patient." | 1.33 | Malignant hyperthermia in China. ( Guo, XY; Huang, YG; Luo, AL; Ren, HZ; Wang, YL; Xu, ZH; Ye, TH; Zhang, X, 2006) |
| "To determine whether malignant hyperthermia (MH) susceptibility in a Canadian pedigree is associated with a mutation in the ryanodine receptor subtype 1 (RYR1) gene, the complete RYR1 transcript obtained from the leukocytes of one MH-susceptible family member was sequenced, using a newly developed protocol." | 1.32 | Detection of a novel ryanodine receptor subtype 1 mutation (R328W) in a malignant hyperthermia family by sequencing of a leukocyte transcript. ( Du, G; Kraev, A; Kraev, N; Loke, JC; MacLennan, DH; Patel, L; Sharma, P, 2003) |
| "The diagnosis of susceptibility to malignant hyperthermia (MH) is currently performed on muscle biopsies subjected to halothane-caffeine in vitro contracture tests (IVCTs)." | 1.32 | Comparative analysis of in vitro contracture tests with ryanodine and a combination of ryanodine with either halothane or caffeine: a comparative investigation in malignant hyperthermia. ( Bendahan, D; Cozzone, PJ; Ghattas, B; Guis, S; Kozak-Ribbens, G; Lunardi, J; Mattei, JP; Monnier, N, 2004) |
| "The diagnostic outcomes of tests for malignant hyperthermia susceptibility were compared between two laboratories by using muscle tissue from the same patients." | 1.31 | Between-center variability of results of the in vitro contracture test for malignant hyperthermia susceptibility. ( Bendixen, D; Islander, G; Ording, H; Ranklev-Twetman, E, 2000) |
| "Xenon 70% did not cause an increase in baseline tension of any MH-susceptible muscle specimen in contrast to halothane and caffeine." | 1.31 | Xenon does not induce contracture in human malignant hyperthermia muscle. ( Baur, CP; Froeba, G; Georgieff, M; Jurkat-Rott, K; Klingler, W; Lehmann-Horn, F; Marx, T; Schoch, E, 2000) |
| "The determination of susceptibility to malignant hyperthermia (MH) by genetic investigation is a controversial issue because of the genetic heterogeneity of this disorder." | 1.31 | Homozygous and heterozygous Arg614Cys mutations (1840C-->T) in the ryanodine receptor gene co-segregate with malignant hyperthermia susceptibility in a German family. ( Deutrich, C; Froster, UG; Olthoff, D; Rueffert, H; Thamm, B, 2001) |
| " MHEh muscles revealed a dose-response curve similar to that found in MHN specimens." | 1.30 | Classification of malignant hyperthermia-equivocal patients by 4-chloro-M-cresol. ( Bittner, RE; Fricker, R; Gilly, H; Kress, HG; Musat, I; Steinbereithner, K, 1997) |
| "Chlorocresol was demonstrated to be a potent activator of Ca++ release from skeletal muscle sarcoplasmic reticulum." | 1.30 | [Effect of chlorocresol vs caffeine on muscle contracture in malignant hyperthermia susceptible patients]. ( Adnet, PJ; Ben-Abraham, R; Haudcoeur, G; Krivosic-Horber, RM; Perel, A, 1997) |
| "The association between malignant hyperthermia (MH) and neuromuscular disorders is controversial." | 1.30 | Dystrophin deficient mdx muscle is not prone to MH susceptibility: an in vitro study. ( Bittner, RE; Gilly, H; Mader, N, 1997) |
| "Gentamicin did not cause a decrease in initial muscular strength, nor did it impair the muscles' ability to sustain strength." | 1.30 | Effects of high-dose gentamicin sulfate on neuromuscular blockade in halothane-anesthetized horses. ( Hague, BA; Hartsfield, SM; Martinez, EA, 1997) |
| "Pretreatment with halothane significantly diminished carbachol-induced increases in [Ca2+]i by 77% and muscle tension by 83% in a dose-dependent manner." | 1.30 | Role of intracellular Ca2+ stores in the inhibitory effect of halothane on airway smooth muscle contraction. ( Kohro, S; Matsuzaki, T; Namiki, A; Tsuchida, H; Yamakage, M, 1998) |
| "Regulation of muscle contraction is abnormal in Thoroughbreds with RER." | 1.30 | Abnormal regulation of muscle contraction in horses with recurrent exertional rhabdomyolysis. ( Balog, EM; Gallant, EM; Lentz, LR; Mickelson, JR; Valberg, SJ, 1999) |
| "Anaesthesia-induced malignant hyperthermia (MH) may be caused by specific gene defects in the skeletal muscle ryanodine receptor." | 1.29 | Genotype and phenotype relationships for mutations in the ryanodine receptor in patients referred for diagnosis of malignant hyperthermia. ( Fletcher, JE; Hubert, M; Levitt, RC; Rosenberg, H; Tripolitis, L; Vita, GM, 1995) |
| "A 3% halothane-induced increase in [Ca2+]cyt was observed in the Ca(2+)-free solution even when the muscle strip was pretreated with a 10(-6)-M dose of ryanodine and a 20-mM dose of caffeine, whereas it was abolished completely after the muscle strip was pretreated with ryanodine, caffeine, and 100 nM norepinephrine." | 1.29 | Effects of halothane and isoflurane on cytosolic calcium ion concentrations and contraction in the vascular smooth muscle of the rat aorta. ( Fujita, S; Namba, H; Namiki, A; Notsuki, E; Tsuchida, H; Yamakage, M, 1993) |
| " The preparations were then exposed to up to 4 vol% volatile agent incrementally to generate a cumulative dose-response curve, and the subsequent frequency of peristaltic contractions was determined." | 1.29 | Volatile anesthetics decrease peristalsis in the guinea pig ureter. ( Attele, A; Moss, J; Núñez, R; Toledano, A; Young, CJ, 1994) |
| "6 MAC halothane did not significantly affect the dose-response relationship between isoproterenol and force." | 1.29 | Halothane and pertussis toxin-sensitive G proteins in airway smooth muscle. ( Jones, KA; Morimoto, N; Warner, DO; Yamamoto, K, 1994) |
| "Halothane is a potent bronchodilator that attenuates vagally mediated constriction of canine airways, in part by a direct action on the smooth muscle cell." | 1.29 | Halothane alters cytosolic calcium transient in tracheal smooth muscle. ( Housmans, PR; Jones, KA; Lorenz, RR; Rehder, K; Warner, DO, 1993) |
| "Atracurium was again given by infusion to maintain 40% twitch for a second hour, then 2 mg gentamycin/kg bwt were given i." | 1.29 | Interaction of gentamycin and atracurium in anaesthetised horses. ( Hildebrand, SV; Hill, T, 1994) |
| "In vitro, prospective, repeated-measures, dose-response study." | 1.29 | Effect of halothane on phenylephrine-induced vascular smooth muscle contractions in endotoxin-exposed rat aortic rings. ( Bina, S; Grissom, TE; Hart, J; Muldoon, SM, 1996) |
| "Halothane or isoflurane was aerated into four tissue baths, while the remaining four served as time controls." | 1.29 | Effects of halothane and isoflurane on antigen- and leukotriene-D4-induced constriction of guinea pig trachea. ( Bosnjak, ZJ; Coon, RL; Kampine, JP; Tudoric, N, 1995) |
| "Rocuronium was administered as an initial bolus dose of 0." | 1.29 | Pharmacokinetics of rocuronium after bolus and continuous infusion during halothane anaesthesia. ( Maddineni, VR; McCoy, EP; Mirakhur, RK; Proost, JH; Wierda, JM, 1996) |
| "We have recently shown that permeability pulmonary edema led to active expiratory glottic closure in awake newborn lambs while hypoxia (inspired O2 fraction 8%; 15 min) did not." | 1.29 | Inferior pharyngeal constrictor electromyographic activity during permeability pulmonary edema in lambs. ( Diaz, V; Kianicka, I; Letourneau, P; Praud, JP, 1996) |
| "1." | 1.28 | W-7, a calmodulin antagonist, and contracture of malignant hyperthermia susceptible skeletal muscle. ( Holland, M; Lee, JC; Williams, JH, 1992) |
| "Isoflurane has a lesser ability than halothane to induce contracture in malignant hyperthermia (MH) muscle in vitro." | 1.28 | Effect of Bay K 8644 on the magnitude of isoflurane and halothane contracture of skeletal muscle from patients susceptible to malignant hyperthermia. ( Adamantidis, MM; Adnet, PJ; Haudecoeur, G; Imbenotte, M; Krivosic-Horber, RM; Reyford, H, 1992) |
| "2." | 1.28 | Propofol anaesthesia in malignant hyperpyrexia susceptible swine. ( Denborough, MA; Foster, PS; Hopkinson, KC, 1992) |
| "In vitro muscle contracture tests for malignant hyperthermia screening are routinely performed using standardized protocols." | 1.28 | Effect of halothane equilibration kinetics on in vitro muscle contractures for malignant hyperthermia screening. ( Censier, K; Drewe, J; Funk, B; Urwyler, A, 1992) |
| "Until our malignant hyperthermia diagnostic center was opened, such tests could not be performed in Israel." | 1.28 | [In vitro diagnosis of malignant hyperpyrexia syndrome]. ( Eldar, I; Glauber, V; Goldberg, G; Perel, A, 1991) |
| "The inheritance of malignant hyperthermia susceptibility is thought to be autosomal dominant and the incidence could be as high as 1:10,000." | 1.28 | [Diagnosis of susceptibility for malignant hyperthermia using in-vitro muscle contraction testing in Switzerland]. ( Censier, K; Drewe, J; Frei, F; Rothenbühler, JM; Seeberger, MD; Urwyler, A, 1991) |
| "Based on studies in swine, the malignant hyperthermia syndrome has been postulated to result from an enhanced sensitivity (low threshold) of the Ca2(+)-induced Ca2(+)-release process." | 1.28 | Fatty acids modulate calcium-induced calcium release from skeletal muscle heavy sarcoplasmic reticulum fractions: implications for malignant hyperthermia. ( Beech, J; Conti, PA; Erwin, K; Fletcher, JE; Hanson, S; Rosenberg, H; Tripolitis, L, 1990) |
| "Halothane was found to increase the train-of-four fade during the recovery phase compared with control." | 1.28 | Influence of halothane on the train-of-four fade after atracurium in children. ( Woloszczuk-Gebicka, B, 1990) |
| "Both morphine and halothane produce a dose-related inhibition of electrically induced muscle contraction." | 1.28 | Synergistic interaction of morphine and halothane in the guinea pig ileum: effects of pertussis toxin. ( Puig, MM; Turndorf, H; Warner, W, 1990) |
| "To determine whether a malignant hyperthermia (MH) episode could nevertheless be provoked by a more rigorous challenge, both genetically MHS (Pietrain) and normal (Yorkshire) 5-wk-old piglets were exposed to a combined halothane-succinylcholine challenge." | 1.28 | Halothane sensitivity of young pigs in vivo and in vitro. ( Fay, RS; Gallant, EM, 1990) |
| " The dose-response curve for the halothane-induced contractures of Ca2(+)-loaded skinned fibers was displaced to the left after denervation." | 1.28 | Alterations in the functional properties of skinned fibers from denervated rabbit skeletal muscle. ( Suarez-Kurtz, G; Sudo, RT; Trachez, MM, 1990) |
| "A halothane-induced increase in time-to-peak contraction was also observed at membrane potentials in the range of the action potential plateau (+20 and +40 mV)." | 1.28 | Influence of halothane on contraction at positive membrane potentials in single cells isolated from guinea-pig ventricular muscle. ( Terrar, DA; Victory, JG, 1989) |
| "Halothane-induced malignant hyperthermia (MH) is thought to result from a defect in the regulation of cytosolic calcium concentration in MH-susceptible (MHS) skeletal muscle." | 1.28 | Porcine malignant hyperthermia: halothane effects on force generation in skeletal muscles. ( Gallant, EM; Goettl, VM, 1989) |
| " They then compared these dose-response relationships with values obtained for adults (greater than 18 years old) under comparable anesthetic conditions." | 1.27 | Neuromuscular effects of vecuronium (ORG NC45) in infants and children during N2O, halothane anesthesia. ( Fisher, DM; Miller, RD, 1983) |
| "Midazolam is a water soluble benzodiazepine of interest to the anaesthetist for use as a premedicant and for induction of anaesthesia." | 1.27 | Effects of midazolam on directly stimulated muscle biopsies from control and malignant hyperthermia positive patients. ( Fletcher, JE; Hilf, M; Rosenberg, H, 1984) |
| "Pancuronium bromide was administered to calves to define the dosage level necessary to produce surgical relaxation (90% to 99% reduction of base-line evoked, hindlimb digital-extensor muscle twitch tension)." | 1.27 | Neuromuscular and cardiovascular effects of pancuronium bromide in calves anesthetized with halothane. ( Hildebrand, SV; Howitt, GA, 1984) |
| "The caffeine test was positive in 68% of MHS patients, 0." | 1.27 | Investigation of malignant hyperthermia in Denmark and Sweden. ( Fletcher, R; Ording, H; Ranklev, E, 1984) |
| "A European Malignant Hyperpyrexia Group has been formed to facilitate exchange of information between centres performing in vitro muscle testing for malignant hyperpyrexia susceptibility." | 1.27 | A protocol for the investigation of malignant hyperpyrexia (MH) susceptibility. The European Malignant Hyperpyrexia Group. ( , 1984) |
| "Amrinone (0." | 1.27 | Inotropic effect of amrinone in rabbit papillary muscle: reversal of the myocardial depressant effect of halothane. ( Komai, H; Rusy, BF, 1984) |
| "Enflurane has a significantly greater synergistic effect than halothane." | 1.27 | Differential increase in potency of neuromuscular blocking agents by enflurane and halothane. ( Schuh, FT, 1983) |
| "Simultaneous pharmacokinetic and pharmacodynamic measurements were made in six patients following atracurium 0." | 1.27 | Combined pharmacokinetic and pharmacodynamic study of a single bolus dose of atracurium. ( Ward, S; Wright, D, 1983) |
| "Though a malignant hyperthermia (MH) crisis is still a critical event during general anesthesia, recent developments in prophylaxis and treatment should help in avoiding fatal episodes." | 1.27 | [Diagnosis of susceptibility to malignant hyperthermia using the in vitro contracture test]. ( Klein, W; Küther, G; Lehmann-Horn, F; Pongratz, D; Spiess-Kiefer, C, 1987) |
| " The dose-response curve for vecuronium was determined after the injection of a single bolus (40, 55 or 70 micrograms kg-1) to 33 patients." | 1.27 | Clinical pharmacology of vecuronium in children. Studies during nitrous oxide and halothane in oxygen anaesthesia. ( da Silva, GL; Delleur, MM; Loose, JP; Meistelman, C; Saint-Maurice, C, 1986) |
| "The halothane-induced increase in [Ca2+]i required extracellular calcium ions." | 1.27 | Anaesthetic-induced increase in ionised calcium in blood mononuclear cells from malignant hyperthermia patients. ( Britt, BA; Elliott, ME; Frodis, W; Klip, A; Pegg, W; Scott, E, 1987) |
| "Caffeine contractures were recorded from thin bundles and whole extensor digitorum longus (EDL) and soleus muscles of rat, and correlated with preparation size and fiber types." | 1.27 | Effect of fiber types, fascicle size and halothane on caffeine contractures in rat muscles. ( Pagala, MK; Sahgal, V; Shah, AJ; Subramani, V; Venkatachari, SA, 1988) |
| "1." | 1.27 | Calmodulin-antagonist drugs and porcine malignant hyperpyrexia. ( Collins, SP; Denborough, MA; White, MD, 1988) |
| " Hill coefficients derived from dose-response curves were less than one for morphine or halothane alone, while it was 1." | 1.27 | Synergistic interaction of morphine and halothane in the guinea pig ileum. ( Lovitz, M; Puig, MM; Tang, CK; Turndorf, H; Warner, W, 1988) |
| "The association of malignant hyperthermia (MH) with neuromuscular disorders has been recognized since 1970." | 1.27 | Halothane-caffeine contracture testing in neuromuscular diseases. ( Fletcher, JE; Heiman-Patterson, TD; Rosenberg, H; Tahmoush, AJ, 1988) |
| "Atracurium did not cause cardiovascular changes." | 1.27 | Neuromuscular and cardiovascular effects of atracurium administered to healthy horses anesthetized with halothane. ( Arpin, D; Hildebrand, SV, 1988) |
| "The acute malignant hyperthermia crisis appears to be mediated by a sudden and sustained rise in the concentration of sarcoplasmic calcium, leading to a prolonged muscle contraction." | 1.27 | Abnormal relaxation rates in subjects susceptible to malignant hyperthermia. ( Henriksson, KG; Lennmarken, C; Rutberg, H, 1987) |
| "In vitro tests for the diagnosis of malignant hyperthermia susceptibility were performed in 105 patients and 20 normal controls according to the protocol of the European MH Group." | 1.27 | In vitro diagnosis of susceptibility to malignant hyperthermia: comparison between dynamic and static halothane and caffeine tests. ( Ording, H; Skovgaard, LT, 1987) |
| "Halothane was administered during 30 min at a constant minimum alveolar concentration (MAC): 0." | 1.27 | Different effects of halothane on diaphragm and hindlimb muscle in rats. ( Aubier, M; Desmonts, JM; Dureuil, B; Fiks, M; Nivoche, Y; Pariente, R; Viirès, N, 1987) |
| " Group B (n = 10), H24 (n = 5), and H72 (n = 5) were anesthetized with sodium thiamylal (B) or halothane and N2O (H24, H72) for 3 h, during which a dose-response curve to histamine was obtained." | 1.27 | Prolonged hyporesponsiveness of airway smooth muscle to histamine following general anesthesia. ( Amyot, R; Chapleau, D; Couture, J; Michoud, MC; St-Jean, S, 1986) |
| "To diagnose malignant hyperthermia susceptibility (MHS), caffeine and halothane contracture tests were performed on six patients." | 1.27 | [Detection of peranesthetic malignant hyperthermia by muscle contracture tests and NMR spectroscopy]. ( Gascard, JP; Kozak-Reiss, G; Redouane-Bénichou, K, 1986) |
| "No abnormality in malignant hyperpyrexia susceptible muscle was found." | 1.26 | Effect of halothane on adenylate kinase in porcine malignant hyperpyrexia. ( Denborough, MA; Marjanen, LA, 1982) |
| "Verapamil was found to potentiate the halothane-aminophylline interaction, whereas di-Na-EDTA depressed it." | 1.26 | Interaction of halothane and aminophylline on the isolated hemidiaphragm of the rat. ( Kentera, D; Prostran, M; Varagić, VM, 1980) |
| "1 The tetanic and single twitch responses to the adductor pollicis muscle were used to study the neuromuscular effects of repeated dosage of decamethonium in nine anaesthetized patients." | 1.26 | Tachyphylaxis after repeated dosage of decamethonium in anaesthetized man. ( Al-Azawi, S; Hughes, R; Payne, JP, 1982) |
| "Edrophonium (0." | 1.26 | Edrophonium: duration of action and atropine requirement in humans during halothane anesthesia. ( Cronnelly, R; Miller, RD; Morris, RB, 1982) |
| "Ether was associated with periods of intense activity throughout anaesthesia and this activity persisted after recovery of consciousness." | 1.26 | Effects of inhalation anaesthetic agents on the electrical and mechanical activity of the rat duodenum. ( Balfour, TW; Hardcastle, JD; Healy, TE; Wright, JW, 1982) |
| "Atracurium is a potent competitive neuromuscular blocking agent in anesthetized man with no cardiovascular effects at doses required for paralysis." | 1.26 | Evaluation of atracurium in anaesthetized man. ( Hughes, R; Payne, JP, 1981) |
| "In this Research Conference we define malignant hyperthermia, present its brief history, and describe the diagnostic procedures and directions of research in our laboratory." | 1.26 | Malignant hyperthermia: diagnosis, treatment and investigations of a skeletal muscle lesion. ( Flewellen, EH; Nelson, TE, 1979) |
| "In most "malignant hyperpyrexia" families the susceptible patients had either normal or inconsistently raised CPK values." | 1.25 | Evaluation of creatinine phosphokinase in screening patients for malignant hyperpyrexia. ( Clarke, IM; Currie, S; Ellis, FR; Harriman, DG; Modgill, M, 1975) |
| "The methods used to screen patients for malignant hyperpyrexia at present are not sufficiently accurate." | 1.25 | Screening for malignant hyperpyrexia. ( Ellis, FR; Hargreaves, JB; Harriman, DG; Keaney, NP; Kyei-Mensah, K; Mulrooney, PL; Parikh, RK; Sumner, DW; Tyrrell, JH, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 266 (52.47) | 18.7374 |
| 1990's | 167 (32.94) | 18.2507 |
| 2000's | 52 (10.26) | 29.6817 |
| 2010's | 21 (4.14) | 24.3611 |
| 2020's | 1 (0.20) | 2.80 |
| Authors | Studies |
|---|---|
| Figueroa, L | 2 |
| Kraeva, N | 3 |
| Manno, C | 2 |
| Ibarra-Moreno, CA | 1 |
| Tammineni, ER | 1 |
| Riazi, S | 3 |
| Rios, E | 2 |
| Thompson, SJ | 1 |
| Noseworthy, MD | 1 |
| Rayner, TE | 1 |
| Schneiderman, JE | 1 |
| Cifra, B | 1 |
| Wells, GD | 1 |
| Zullo, A | 1 |
| Textor, M | 1 |
| Elischer, P | 1 |
| Mall, S | 1 |
| Alt, A | 1 |
| Klingler, W | 6 |
| Melzer, W | 1 |
| Johannsen, S | 4 |
| Schick, M | 1 |
| Roewer, N | 9 |
| Schuster, F | 6 |
| Türkmeneli, I | 1 |
| Isbary, S | 1 |
| Toro, S | 1 |
| Brandom, BW | 4 |
| Bina, S | 5 |
| Wong, CA | 1 |
| Wallace, T | 1 |
| Visoiu, M | 1 |
| Isackson, PJ | 1 |
| Vladutiu, GD | 1 |
| Sambuughin, N | 1 |
| Muldoon, SM | 10 |
| Hoppe, K | 2 |
| Lehmann-Horn, F | 12 |
| Chaiklieng, S | 1 |
| Jurkat-Rott, K | 2 |
| Adolph, O | 1 |
| Schneiderbanger, D | 2 |
| Heiderich, S | 1 |
| Schleip, R | 1 |
| Jäger, H | 1 |
| Sagui, E | 1 |
| Montigon, C | 1 |
| Abriat, A | 1 |
| Jouvion, A | 1 |
| Duron-Martinaud, S | 1 |
| Canini, F | 2 |
| Zagnoli, F | 1 |
| Bendahan, D | 3 |
| Figarella-Branger, D | 2 |
| Brégigeon, M | 1 |
| Brosset, C | 1 |
| Vellecco, V | 1 |
| Mancini, A | 1 |
| Ianaro, A | 1 |
| Calderone, V | 1 |
| Attanasio, C | 1 |
| Cantalupo, A | 1 |
| Andria, B | 1 |
| Savoia, G | 1 |
| Panza, E | 1 |
| Di Martino, A | 1 |
| Cirino, G | 1 |
| Bucci, M | 1 |
| Treves, S | 2 |
| Müller, CR | 1 |
| Mögele, S | 1 |
| Kollmann-Camaiora, A | 1 |
| Alsina, E | 1 |
| Domínguez, A | 1 |
| Del Blanco, B | 1 |
| Yepes, MJ | 1 |
| Guerrero, JL | 1 |
| García, A | 1 |
| Kaufmann, A | 1 |
| Kraft, B | 2 |
| Michalek-Sauberer, A | 2 |
| Weigl, LG | 2 |
| Parness, J | 1 |
| Carpenter, D | 2 |
| Robinson, RL | 2 |
| Quinnell, RJ | 1 |
| Ringrose, C | 2 |
| Hogg, M | 1 |
| Casson, F | 1 |
| Booms, P | 1 |
| Iles, DE | 1 |
| Halsall, PJ | 9 |
| Steele, DS | 1 |
| Shaw, MA | 2 |
| Hopkins, PM | 8 |
| Leo, V | 1 |
| Morris, A | 1 |
| Shiina, T | 1 |
| Shima, T | 1 |
| Masuda, K | 1 |
| Hirayama, H | 1 |
| Iwami, M | 1 |
| Takewaki, T | 1 |
| Kuramoto, H | 1 |
| Shimizu, Y | 1 |
| Wang, YL | 2 |
| Luo, AL | 2 |
| Tan, G | 1 |
| Cui, XL | 1 |
| Guo, XY | 2 |
| Metterlein, T | 2 |
| Kranke, P | 1 |
| Anetseder, M | 5 |
| Urwyler, A | 11 |
| Schütte, JK | 1 |
| Becker, S | 1 |
| Burmester, S | 1 |
| Starosse, A | 1 |
| Lenz, D | 1 |
| Kröner, L | 1 |
| Wappler, F | 12 |
| Gerbershagen, MU | 2 |
| Hartung, E | 6 |
| Lacava, C | 1 |
| Sgaragli, G | 1 |
| Sipos, E | 1 |
| Höller, C | 1 |
| Kress, HG | 2 |
| Fusi, F | 1 |
| Sundblom, J | 1 |
| Melberg, A | 1 |
| Rücker, F | 1 |
| Smits, A | 1 |
| Islander, G | 8 |
| Etchrivi, TS | 5 |
| Adnet, P | 3 |
| Haudecoeur, G | 14 |
| Teneur, F | 1 |
| Stix, I | 2 |
| Krivosic-Horber, RM | 14 |
| Fiege, M | 4 |
| Weisshorn, R | 3 |
| Ulrich Gerbershagen, M | 1 |
| Steinfath, M | 5 |
| Schulte Am Esch, J | 4 |
| Ording, H | 12 |
| Bendixen, D | 4 |
| Ranklev Twetman, E | 3 |
| Bouhemad, B | 2 |
| Langeron, O | 2 |
| Orliaguet, G | 2 |
| Coriat, P | 2 |
| Riou, B | 2 |
| Allen, PD | 1 |
| López, JR | 2 |
| Sei, Y | 1 |
| Hosoi, E | 1 |
| Gallagher, KL | 1 |
| Wyre, HW | 1 |
| Pudimat, PA | 1 |
| Holman, SJ | 1 |
| Venzon, DJ | 1 |
| Daly, JW | 1 |
| Muldoon, S | 3 |
| Holman, S | 1 |
| Lecarpentier, Y | 1 |
| Bergner, A | 1 |
| Sanderson, MJ | 1 |
| Loke, JC | 1 |
| Kraev, N | 1 |
| Sharma, P | 1 |
| Du, G | 1 |
| Patel, L | 2 |
| Kraev, A | 1 |
| MacLennan, DH | 4 |
| Baur, CP | 2 |
| Censier, K | 7 |
| Doetsch, S | 1 |
| Felleiter, P | 1 |
| Fricker, R | 2 |
| Heffron, JJ | 5 |
| Heytens, L | 3 |
| Nivoche, Y | 3 |
| Tegazzin, V | 2 |
| Tzanova, I | 1 |
| RANG, HP | 1 |
| MAGURNO, G | 2 |
| PALMISANO, A | 2 |
| Wehner, M | 2 |
| Rueffert, H | 6 |
| Koenig, F | 2 |
| Olthoff, D | 7 |
| Deutrich, C | 4 |
| Schober, R | 1 |
| Froster, UG | 4 |
| Nelson, TE | 19 |
| Rosenberg, H | 30 |
| Ginz, HF | 1 |
| Girard, T | 3 |
| Sakihara, C | 1 |
| Perkins, WJ | 1 |
| Warner, DO | 8 |
| Jones, KA | 7 |
| Guis, S | 1 |
| Monnier, N | 1 |
| Kozak-Ribbens, G | 3 |
| Lunardi, J | 1 |
| Ghattas, B | 2 |
| Mattei, JP | 1 |
| Cozzone, PJ | 2 |
| Litman, RS | 1 |
| Dranchak, PK | 1 |
| Valberg, SJ | 2 |
| Onan, GW | 1 |
| Gallant, EM | 11 |
| MacLeay, JM | 1 |
| McKenzie, EC | 1 |
| De La Corte, FD | 1 |
| Ekenstedt, K | 1 |
| Mickelson, JR | 4 |
| Marsala, M | 1 |
| Hefferan, MP | 1 |
| Kakinohana, O | 1 |
| Nakamura, S | 1 |
| Marsala, J | 1 |
| Tomori, Z | 1 |
| Xu, ZH | 1 |
| Ren, HZ | 1 |
| Zhang, X | 1 |
| Huang, YG | 1 |
| Ye, TH | 1 |
| Rydenfelt, K | 1 |
| Ranklev, E | 3 |
| Bodelsson, M | 1 |
| Bross, T | 1 |
| Steinmann, D | 1 |
| Ortiz Gómez, JR | 1 |
| Moya, F | 2 |
| Fahey, MR | 1 |
| Morris, RB | 2 |
| Miller, RD | 6 |
| Sohn, YJ | 1 |
| Cronnelly, R | 2 |
| Gencarelli, P | 1 |
| Tollefson, G | 1 |
| Caroff, S | 1 |
| Gerber, JC | 1 |
| Fisher, DM | 1 |
| Engbaek, J | 1 |
| Viby-Mogensen, J | 2 |
| Fletcher, JE | 20 |
| Hilf, M | 1 |
| Hughes, R | 7 |
| Chapple, DJ | 1 |
| Goudsouzian, NG | 2 |
| Varagić, VM | 2 |
| Prostran, M | 2 |
| Marjanen, LA | 1 |
| Denborough, MA | 14 |
| Flewellen, EH | 9 |
| Arnett, DW | 1 |
| Korenaga, S | 1 |
| Takeda, K | 1 |
| Ito, Y | 2 |
| Mori, K | 4 |
| Shingu, K | 2 |
| van den Hende, C | 3 |
| Muylle, E | 3 |
| Vlaminck, K | 1 |
| Oyaert, W | 3 |
| Hildebrand, SV | 6 |
| Howitt, GA | 1 |
| Fletcher, R | 2 |
| Iwatsuki, N | 3 |
| Koga, Y | 1 |
| Amaha, K | 3 |
| Rorie, DK | 2 |
| Tyce, GM | 2 |
| Mackenzie, RA | 1 |
| Komai, H | 1 |
| Rusy, BF | 2 |
| Schuh, FT | 1 |
| Takatsuka, K | 1 |
| Miyamoto, S | 1 |
| Tamiya, T | 1 |
| Gotoh, Y | 1 |
| Ward, S | 1 |
| Wright, D | 1 |
| Stirt, JA | 1 |
| Katz, RL | 4 |
| Murray, AL | 1 |
| Schehl, DL | 1 |
| Lee, C | 2 |
| Kentera, D | 1 |
| Reed, S | 1 |
| Gloyna, DF | 1 |
| Klein, C | 1 |
| Hopkins, J | 2 |
| Beck, E | 2 |
| Burton, B | 2 |
| Klein, L | 1 |
| Ellis, FR | 16 |
| Anderson, IL | 2 |
| Rawstron, RE | 1 |
| Dunlop, DJ | 1 |
| Sporn, P | 2 |
| Godt, RE | 1 |
| Gronert, GA | 10 |
| Al-Azawi, S | 1 |
| Payne, JP | 5 |
| Delisle, S | 1 |
| Bevan, DR | 1 |
| Taylor, SR | 2 |
| Brownell, AK | 2 |
| Szabo, M | 1 |
| Mortier, W | 3 |
| Biesel, C | 1 |
| Wright, JW | 1 |
| Healy, TE | 1 |
| Balfour, TW | 1 |
| Hardcastle, JD | 1 |
| Britt, BA | 12 |
| Frodis, W | 4 |
| Scott, E | 3 |
| Clements, MJ | 1 |
| Endrenyi, L | 3 |
| Thompson, RL | 1 |
| Onofrio, BM | 1 |
| Su, JY | 3 |
| Rothhammer, A | 1 |
| Weis, KH | 1 |
| Skrobek, W | 1 |
| Schmidt, E | 1 |
| Bruch, P | 1 |
| Trenkel, K | 1 |
| Sullivan, JS | 1 |
| Green, RA | 1 |
| Mitchell, G | 1 |
| Al Azawi, S | 1 |
| Okumura, F | 2 |
| Crocker, BD | 2 |
| Oshima, E | 1 |
| Coleman, AW | 1 |
| Coleman, JR | 1 |
| Tripolitis, L | 5 |
| Hubert, M | 1 |
| Vita, GM | 1 |
| Levitt, RC | 1 |
| Klont, RE | 1 |
| Lambooy, E | 1 |
| Sato, J | 1 |
| Shinozuka, N | 1 |
| Kochi, A | 1 |
| Uchida, H | 1 |
| Mizuguchi, T | 3 |
| Singh, S | 2 |
| Scholz, J | 5 |
| Becker, K | 1 |
| Lenzen, C | 1 |
| Köchling, A | 4 |
| Shi, Y | 1 |
| Keykhah, MM | 2 |
| Storella, RJ | 2 |
| Beech, J | 5 |
| Lindborg, S | 2 |
| Dawso, T | 1 |
| Tsuchida, H | 4 |
| Namba, H | 2 |
| Yamakage, M | 5 |
| Fujita, S | 2 |
| Notsuki, E | 1 |
| Namiki, A | 6 |
| Foster, PS | 6 |
| Yamamoto, K | 2 |
| Morimoto, N | 2 |
| Rehder, K | 3 |
| Leevers, AM | 1 |
| Road, JD | 1 |
| Sato, N | 1 |
| Brum, JM | 1 |
| Mitsumoto, H | 1 |
| DeBoer, GE | 1 |
| Dickinson, PJ | 1 |
| Sullivan, M | 1 |
| Akata, T | 1 |
| Boyle, WA | 1 |
| Kawamata, T | 2 |
| Kohro, S | 3 |
| Kaplan, RF | 1 |
| Garcia, M | 1 |
| Hannallah, RS | 1 |
| Klepper, S | 1 |
| Reichmann, H | 1 |
| Kaufmann, MA | 2 |
| Drewe, J | 4 |
| Yamazaki, M | 1 |
| Momose, Y | 1 |
| Ozhan, M | 1 |
| Sill, JC | 3 |
| Atagunduz, P | 1 |
| Martin, R | 1 |
| Katusić, ZS | 1 |
| Young, CJ | 1 |
| Attele, A | 1 |
| Toledano, A | 1 |
| Núñez, R | 1 |
| Moss, J | 1 |
| Saitoh, Y | 1 |
| Toyooka, H | 1 |
| Adnet, PJ | 15 |
| Krivosic, I | 1 |
| Reyford, HG | 4 |
| Adamantidis, MM | 8 |
| Medahoui, H | 1 |
| Wong, GY | 1 |
| Lorenz, RR | 3 |
| Sieck, GC | 1 |
| Seki, S | 1 |
| Tanaka, S | 2 |
| Housmans, PR | 2 |
| Isaacs, H | 3 |
| Badenhorst, M | 2 |
| Calvo, PA | 1 |
| Seeberger, MD | 2 |
| Rothenbühler, JM | 2 |
| Lizzo, F | 1 |
| Braund, K | 1 |
| Kamath, GS | 1 |
| Payen, JF | 2 |
| Bosson, JL | 2 |
| Bourdon, L | 2 |
| Jacquot, C | 1 |
| Le Bas, JF | 1 |
| Stieglitz, P | 3 |
| Benabid, AL | 1 |
| Hill, T | 3 |
| Serfas, KD | 1 |
| Bose, D | 1 |
| Wrogemann, K | 1 |
| Phillips, MS | 1 |
| Greenberg, CR | 1 |
| Grissom, TE | 1 |
| Hart, J | 2 |
| Tudoric, N | 1 |
| Coon, RL | 1 |
| Kampine, JP | 3 |
| Bosnjak, ZJ | 3 |
| Tavernier, BM | 1 |
| Haddad, E | 1 |
| Lacroix, D | 1 |
| Reyford, H | 6 |
| Löscher, W | 1 |
| McCoy, EP | 1 |
| Mirakhur, RK | 2 |
| Maddineni, VR | 1 |
| Wierda, JM | 1 |
| Proost, JH | 1 |
| Koob, M | 1 |
| Schoemig, P | 1 |
| Krauspe, R | 2 |
| Hogrefe, G | 1 |
| Engelhardt, W | 2 |
| Wieland, SJ | 4 |
| Gong, QH | 2 |
| Mercier, FJ | 1 |
| Denjean, A | 1 |
| Sessler, DI | 1 |
| Diaz, V | 1 |
| Kianicka, I | 1 |
| Letourneau, P | 1 |
| Praud, JP | 1 |
| Kai, T | 2 |
| Takahashi, S | 1 |
| Kanaide, H | 1 |
| Owen, VJ | 2 |
| Taske, NL | 2 |
| Lamb, GD | 2 |
| Weglinski, MR | 1 |
| Wedel, DJ | 2 |
| Engel, AG | 1 |
| Fagerlund, TH | 3 |
| Ranklev-Twetman, E | 3 |
| Berg, K | 3 |
| Antognini, JF | 3 |
| Gilly, H | 2 |
| Musat, I | 1 |
| Bittner, RE | 2 |
| Steinbereithner, K | 3 |
| Ben-Abraham, R | 1 |
| Haudcoeur, G | 1 |
| Perel, A | 3 |
| Mader, N | 1 |
| Brancadoro, V | 1 |
| Cozzolino, S | 1 |
| Glauber, V | 3 |
| Gonano, EF | 1 |
| Kress, H | 1 |
| Krivosic-Horber, R | 4 |
| Sigurdsson, S | 1 |
| Snoeck, M | 1 |
| Glahn, K | 1 |
| Gardi, T | 1 |
| Fagerlund, T | 1 |
| Laver, DR | 1 |
| Junankar, PR | 1 |
| Dulhunty, AF | 1 |
| Hague, BA | 1 |
| Martinez, EA | 1 |
| Hartsfield, SM | 1 |
| Mezin, P | 1 |
| Brambilla, E | 1 |
| Ben Abraham, R | 1 |
| Zweig, A | 1 |
| Mendes, LS | 1 |
| Collins, SP | 2 |
| Kagawa, T | 1 |
| Maekawa, N | 1 |
| Mikawa, K | 1 |
| Nishina, K | 1 |
| Yaku, H | 1 |
| Obara, H | 1 |
| Kirkegaard-Nielsen, H | 3 |
| Lindholm, P | 3 |
| Petersen, HS | 1 |
| Severinsen, IK | 3 |
| Halle, I | 1 |
| Kasamatsu, Y | 1 |
| Osada, M | 1 |
| Ashida, K | 1 |
| Azukari, K | 1 |
| Yoshioka, K | 1 |
| Ohsawa, A | 1 |
| Woelfel, SK | 2 |
| Ference, A | 1 |
| Dayal, B | 1 |
| Cook, DR | 2 |
| Kerls, S | 1 |
| Winkler, G | 1 |
| Schulte am Esch, JS | 1 |
| Helbo-Hansen, HS | 1 |
| Pedersen, HS | 2 |
| Schmidt, MB | 1 |
| Matsuzaki, T | 1 |
| Bremerich, DH | 1 |
| Brooksbank, RL | 1 |
| Badenhorst, ME | 1 |
| Savage, N | 1 |
| Ross, AK | 1 |
| Dear, GL | 1 |
| Dear, RB | 1 |
| Margolis, JO | 1 |
| Ginsberg, B | 1 |
| Froemming, GR | 1 |
| Dillane, DJ | 1 |
| Ohlendieck, K | 1 |
| Tavernier, B | 3 |
| Beague, S | 1 |
| Ferri, J | 1 |
| Stewart, SL | 1 |
| Twetman, ER | 1 |
| Diallo, A | 1 |
| Lentz, LR | 1 |
| Balog, EM | 1 |
| Melton, AT | 2 |
| Richter, A | 1 |
| MacPherson, RD | 1 |
| Quail, AW | 1 |
| Kakuyama, M | 2 |
| Nakamura, K | 3 |
| Vinh, VH | 1 |
| Enoki, T | 1 |
| Hirata, S | 1 |
| Toda, H | 1 |
| Fukuda, K | 1 |
| Wiklund, CU | 1 |
| Lim, S | 1 |
| Lindsten, U | 1 |
| Lindahl, SG | 1 |
| Chini, EN | 1 |
| Walker, H | 1 |
| Cohen, KD | 1 |
| Berg, BR | 1 |
| Sarelius, IH | 2 |
| Freymond, D | 1 |
| Dériaz, O | 1 |
| Frascarolo, P | 1 |
| Reiz, S | 1 |
| Jéquier, E | 1 |
| Martens, U | 1 |
| Krause, T | 1 |
| Steinrücke, K | 1 |
| am Esch, JS | 1 |
| Murrant, CL | 1 |
| Froeba, G | 1 |
| Schoch, E | 1 |
| Marx, T | 1 |
| Georgieff, M | 1 |
| Agarwal, K | 1 |
| Matschke, J | 1 |
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| Kalow, W | 5 |
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| Holland, M | 5 |
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| Bollen, BA | 1 |
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| Dupuis, BA | 4 |
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| Van de Kelft, E | 1 |
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| Nishiwaki, T | 1 |
| Miyagishima, T | 1 |
| Oka, N | 1 |
| Preis, I | 1 |
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| Goldberg, G | 1 |
| Poels, PJ | 1 |
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| Stadhouders, AM | 1 |
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| Iaizzo, PA | 6 |
| Gallagher, WJ | 1 |
| Salviati, G | 1 |
| Ceoldo, S | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Freeman-Sheldon Syndrome Evaluation and Diagnosis in Clinical Settings (FSS-EDICT) I: a Case-Control, Cross-Sectional Study of Baseline and Stress Physiology Parameters[NCT01306994] | 0 participants (Actual) | Observational | 2014-03-31 | Withdrawn (stopped due to Lack of patient interest) | |||
| INVIBO: Evaluation of the Feasibility and Tolerance of an Intubation Procedure Performed by Means of the Bonfils Fiberscope in Awake Patients With Predicted Difficult Intubation in the Context of ENT Cancer Surgery[NCT01070537] | Phase 2 | 41 participants (Actual) | Interventional | 2008-02-29 | Completed | ||
| Effect of Deep Curarisation and Reversal With Sugammadex on Surgical Conditions and Perioperative Morbidity in Patients Undergoing Laparoscopic Gastric Bypass Surgery[NCT01748643] | Phase 4 | 60 participants (Actual) | Interventional | 2013-04-30 | Completed | ||
| Implication of Patient in the Making Ready of Recommendations for the Antivitamin K's Gestion in Case of Thrombosis Embolic Venous's Illness. Randomised Study for Clinical Validation.[NCT00227097] | 300 participants | Observational | 2002-12-31 | Terminated | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Measured from the time of first skin incision to completion of skin closure. (NCT01748643)
Timeframe: Participants will be followed for the duration of the laparoscopic gastric bypass surgery, an expected average of 1.5h
| Intervention | minutes (Mean) |
|---|---|
| Deep Neuromuscular Blockade, Reversal With Sugammadex | 61.3 |
| Normal Neuromuscular Blockade, Reversal With Neostigmine | 70.6 |
Forced expiratory volume in 1 second is measured with the Vitalograph® electronic portable peak flow meter. A mean of 3 measurements in the upright posture in bed before and after surgery will be used. (NCT01748643)
Timeframe: Measured the day before surgery and 30min after completion of surgery (when the modified observer's assessment of alertness/sedation scale is 5 (Patient responds readily to name spoken in normal tone))
| Intervention | percent change from baseline (Mean) |
|---|---|
| Deep Neuromuscular Blockade, Reversal With Sugammadex | 45.2 |
| Normal Neuromuscular Blockade, Reversal With Neostigmine | 48.8 |
Forced vital capacity is measured with the Vitalograph® electronic portable peak flow meter. A mean of 3 measurements in the upright posture in bed before and after surgery will be used. (NCT01748643)
Timeframe: Measured the day before surgery and 30min after completion of surgery (when the modified observer's assessment of alertness/sedation scale is 5 (Patient responds readily to name spoken in normal tone))
| Intervention | percent change from baseline (Mean) |
|---|---|
| Deep Neuromuscular Blockade, Reversal With Sugammadex | 51.9 |
| Normal Neuromuscular Blockade, Reversal With Neostigmine | 49.0 |
The number of intra-abdominal pressure rises > 18cmH2O detected by the intra-abdominal CO2 insufflator. (NCT01748643)
Timeframe: Participants will be followed for the duration of the laparoscopic gastric bypass surgery, an expected average of 1.5h
| Intervention | number of intra-abdominal pressure rises (Mean) |
|---|---|
| Deep Neuromuscular Blockade, Reversal With Sugammadex | 0.2 |
| Normal Neuromuscular Blockade, Reversal With Neostigmine | 0.3 |
Peak expiratory flow is measured with the Vitalograph® electronic portable peak flow meter. A mean of 3 measurements in the upright posture in bed before and after surgery will be used. (NCT01748643)
Timeframe: Measured the day before surgery and 30min after completion of surgery (when the modified observer's assessment of alertness/sedation scale is 5 (Patient responds readily to name spoken in normal tone))
| Intervention | percent change from baseline (Mean) |
|---|---|
| Deep Neuromuscular Blockade, Reversal With Sugammadex | 51.3 |
| Normal Neuromuscular Blockade, Reversal With Neostigmine | 51.5 |
"At the end of surgery, the view on the operating field will be graded by the surgeon using a 5-point rating scale:~Extremely poor~Poor~Acceptable~Good~Optimal" (NCT01748643)
Timeframe: Participants will be followed for the duration of the laparoscopic gastric bypass surgery, an expected average of 1.5h
| Intervention | units on a scale (Mean) |
|---|---|
| Deep Neuromuscular Blockade, Reversal With Sugammadex | 4.2 |
| Normal Neuromuscular Blockade, Reversal With Neostigmine | 3.9 |
14 reviews available for halothane and Muscle Contraction
| Article | Year |
|---|---|
Clinical protocol for the management of malignant hyperthermia.
Topics: Adolescent; Adult; Caffeine; Calcium Signaling; Child; Child, Preschool; Clinical Protocols; Critica | 2017 |
[Anesthesia in malignant hyperthermia].
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Calcium Signaling; Child; Child, Prescho | 2008 |
[Malignant hyperthermia, syndrome malin, and heat stroke].
Topics: Adolescent; Adult; Anesthesia, Inhalation; Animals; Calcium; Creatine Kinase; Halothane; Heat Exhaus | 1983 |
Epidemiology and inheritance of malignant hyperthermia.
Topics: Adenosine Triphosphate; Caffeine; Creatine Kinase; Female; Genetic Predisposition to Disease; Haloth | 1979 |
Preanesthetic diagnosis of malignant hyperthermia.
Topics: Adenosine Triphosphate; Caffeine; Cardiac Catheterization; Creatine Kinase; Halothane; Heart; Humans | 1979 |
Malignant hyperthermia.
Topics: Anesthesia, Inhalation; Animals; Calcium; Halothane; Humans; Malignant Hyperthermia; Muscle Contract | 1979 |
Halothane-cooling contractures and regulation of the myoplasmic Ca2+ concentration in skeletal muscle.
Topics: Animals; Calcium; Cytoplasm; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Muscles | 1991 |
Malignant hyperthermia: relation to other diseases.
Topics: Caffeine; Calcium Channels; Diagnosis, Differential; Halothane; Humans; Malignant Hyperthermia; Musc | 1990 |
Standardization of the caffeine halothane muscle contracture test. North American Malignant Hyperthermia Group.
Topics: Biopsy; Caffeine; Clinical Laboratory Techniques; Disease Susceptibility; Halothane; Humans; Maligna | 1989 |
Diagnosis of susceptibility to malignant hyperthermia in man.
Topics: Caffeine; Chemistry, Clinical; Disease Susceptibility; Halothane; Hematologic Tests; Humans; In Vitr | 1988 |
Studies of the halothane-cooling contractures of skeletal muscle.
Topics: Anesthetics, Local; Animals; Calcium; Cold Temperature; Dantrolene; Halothane; Humans; Muscle Contra | 1987 |
[Myocardial contractility and anaesthesia].
Topics: Anesthetics; Cardiac Catheterization; Halothane; Heart; Humans; Manometry; Methohexital; Muscle Cont | 1972 |
An appraisal of halothane in obstetrics.
Topics: Anesthesia, Inhalation; Anesthesia, Obstetrical; Cardiac Output; Female; Fetus; Halothane; Humans; H | 1968 |
Cardiovascular function and halothane.
Topics: Anesthesia, Inhalation; Animals; Autonomic Nervous System; Blood Flow Velocity; Blood Pressure; Card | 1968 |
13 trials available for halothane and Muscle Contraction
| Article | Year |
|---|---|
Multicentre evaluation of in vitro contracture testing with bolus administration of 4-chloro-m-cresol for diagnosis of malignant hyperthermia susceptibility.
Topics: Biopsy; Caffeine; Cresols; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant | 2003 |
Neuromuscular blocking effects of vecuronium and pancuronium during halothane anaesthesia.
Topics: Adult; Anesthesia, Inhalation; Female; Halothane; Humans; Muscle Contraction; Neostigmine; Neuromusc | 1983 |
Impaired neostigmine antagonism of pancuronium during enflurane anaesthesia in man.
Topics: Adult; Aged; Anesthesia, Inhalation; Drug Interactions; Enflurane; Halothane; Humans; Middle Aged; M | 1982 |
Onset and recovery of neuromuscular blockade after two doses of rocuronium in children.
Topics: Androstanols; Anesthesia Recovery Period; Anesthetics, Inhalation; Child; Child, Preschool; Elective | 1998 |
Genotype-phenotype comparison of the Swiss malignant hyperthermia population.
Topics: Caffeine; DNA Mutational Analysis; Gene Frequency; Genetic Heterogeneity; Genetic Predisposition to | 2001 |
A comparison of the pharmacodynamics of rocuronium and vecuronium during halothane anaesthesia.
Topics: Adult; Androstanols; Anesthesia, Inhalation; Blood Pressure; Female; Halothane; Heart Rate; Humans; | 1992 |
Neuromuscular effects of pipecuronium bromide.
Topics: Adult; Androstane-3,17-diol; Anesthesia, General; Anesthesia, Inhalation; Female; Fentanyl; Halothan | 1991 |
A blinded comparison of noninvasive, in vivo phosphorus nuclear magnetic resonance spectroscopy and the in vitro halothane/caffeine contracture test in the evaluation of malignant hyperthermia susceptibility.
Topics: Adolescent; Adult; Caffeine; Child; Child, Preschool; Disease Susceptibility; Female; Halothane; Hum | 1991 |
Continuous infusion of mivacurium in children.
Topics: Anesthesia, Inhalation; Child; Fentanyl; Halothane; Humans; Infant; Infusions, Intravenous; Isoquino | 1989 |
Atracurium infusion requirements in children during halothane, isoflurane, and narcotic anesthesia.
Topics: Anesthesia, General; Atracurium; Child; Child, Preschool; Dose-Response Relationship, Drug; Fentanyl | 1985 |
A comparison of atracurium and alcuronium during halothane anaesthesia by measurement of the train-of-four response of the adductor pollicis muscle and clinical observation.
Topics: Adult; Alcuronium; Anesthesia, Inhalation; Atracurium; Female; Halothane; Humans; Intubation, Intrat | 1985 |
[Tocometric studies on halothane and chloroform during the post placental period].
Topics: Anesthesia, Obstetrical; Chloroform; Clinical Trials as Topic; Female; Halothane; Humans; Labor, Obs | 1966 |
Comparative neuromuscular effects of Forane and halothane alone and in combination with d-tubocurarine in man.
Topics: Adult; Anesthetics; Carbon Dioxide; Clinical Trials as Topic; Ethers; Halothane; Humans; Hydrocarbon | 1971 |
480 other studies available for halothane and Muscle Contraction
| Article | Year |
|---|---|
Distinct pathophysiological characteristics in developing muscle from patients susceptible to malignant hyperthermia.
Topics: Caffeine; Calcium; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Muscle Contrac | 2023 |
Skeletal Muscle Metabolic Dysfunction in Patients With Malignant Hyperthermia Susceptibility.
Topics: Adult; Anesthetics; Anthropometry; Caffeine; Case-Control Studies; Disease Susceptibility; Exercise | 2017 |
Voltage modulates halothane-triggered Ca
Topics: Action Potentials; Anesthetics, Inhalation; Animals; Calcium; Cells, Cultured; Fever; Halothane; Mal | 2018 |
Microdialysis and ultrasound elastography for monitoring of localized muscular reaction after pharmacological stimulation in rats.
Topics: Animals; Caffeine; Elasticity Imaging Techniques; Halothane; Malignant Hyperthermia; Microdialysis; | 2018 |
Ultrasound Elastography for Rapid, Real-time Detection of Localized Muscular Reaction in Malignant Hyperthermia-susceptible Pigs.
Topics: Anesthetics, Inhalation; Animals; Caffeine; Central Nervous System Stimulants; Disease Models, Anima | 2018 |
Abnormal calcium signalling and the caffeine-halothane contracture test.
Topics: Adult; Anesthetics, Inhalation; Caffeine; Calcium; Cells, Cultured; Disease Susceptibility; Dose-Res | 2019 |
Ryanodine receptor type 1 gene variants in the malignant hyperthermia-susceptible population of the United States.
Topics: Anesthetics, Inhalation; Calcium Channels; Calcium Channels, L-Type; DNA; Exons; Genetic Variation; | 2013 |
In vitro muscle contracture investigations on the malignant hyperthermia like episodes in myotonia congenita.
Topics: Anesthetics, Inhalation; Animals; Caffeine; Calcium; Central Nervous System Stimulants; Dose-Respons | 2013 |
Sevoflurane is less sensitive than halothane for in vitro detection of malignant hyperthermia susceptibility.
Topics: Anesthetics, Inhalation; Biopsy; Disease Susceptibility; Dose-Response Relationship, Drug; Genetic P | 2013 |
Contractile elements in muscular fascial tissue - implications for in-vitro contracture testing for malignant hyperthermia.
Topics: Anesthesia, General; Anesthetics, General; Animals; Biopsy; Caffeine; Central Nervous System Stimula | 2014 |
Is there a link between exertional heat stroke and susceptibility to malignant hyperthermia?
Topics: Adult; Anesthetics, Inhalation; Caffeine; Contracture; Disease Susceptibility; Female; Halothane; He | 2015 |
Cystathionine β-synthase-derived hydrogen sulfide is involved in human malignant hyperthermia.
Topics: Biopsy; Caffeine; Case-Control Studies; Cystathionine beta-Synthase; Dose-Response Relationship, Dru | 2016 |
Functional characterization of the RYR1 mutation p.Arg4737Trp associated with susceptibility to malignant hyperthermia.
Topics: Anesthetics; Arginine; B-Lymphocytes; Caffeine; Cell Line, Transformed; Cresols; Family Health; Fema | 2016 |
Novel ryanodine receptor mutation that may cause malignant hyperthermia.
Topics: Amino Acid Substitution; Anesthetics, Inhalation; Austria; Caffeine; Calcium; Cells, Cultured; Centr | 2008 |
You're "hot" from pumping iron?
Topics: Anesthesia; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Creatine; Dietary | 2009 |
Genetic variation in RYR1 and malignant hyperthermia phenotypes.
Topics: Anesthetics, Inhalation; Caffeine; Creatine Kinase; DNA Mutational Analysis; DNA, Complementary; Fem | 2009 |
The role of CACNA1S in predisposition to malignant hyperthermia.
Topics: Adolescent; Adult; Aged; Amino Acid Sequence; Caffeine; Calcium Channels; Calcium Channels, L-Type; | 2009 |
Contractile properties of esophageal striated muscle: comparison with cardiac and skeletal muscles in rats.
Topics: Animals; Caffeine; Electric Stimulation; Esophagus; Gap Junctions; Halothane; In Vitro Techniques; M | 2010 |
Clinical features and diagnosis for Chinese cases with malignant hyperthermia: a case cluster from 2005 to 2007.
Topics: Adolescent; Adult; Caffeine; Child; China; Female; Halothane; Humans; In Vitro Techniques; Male; Mal | 2010 |
In-vitro contracture testing for susceptibility to malignant hyperthermia: can halothane be replaced?
Topics: Anesthetics, Inhalation; Biopsy; Case-Control Studies; Desflurane; Dose-Response Relationship, Drug; | 2011 |
Malignant hyperthermia: presymptomatic screening and treatment 2011.
Topics: Anesthetics, Inhalation; Animals; Dantrolene; Halothane; Humans; Malignant Hyperthermia; Muscle Cont | 2011 |
Comparison of the therapeutic effectiveness of a dantrolene sodium solution and a novel nanocrystalline suspension of dantrolene sodium in malignant hyperthermia normal and susceptible pigs.
Topics: Animals; Biomarkers; Chemistry, Pharmaceutical; Dantrolene; Disease Models, Animal; Halothane; Hemod | 2011 |
Sevoflurane as a potential replacement for halothane in diagnostic testing for malignant hyperthermia susceptibility: results of a preliminary study.
Topics: Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Disease Susceptibility; Dose-R | 2011 |
3,5-Di-t-butyl catechol is a potent human ryanodine receptor 1 activator, not suitable for the diagnosis of malignant hyperthermia susceptibility.
Topics: Caffeine; Calcium; Calcium Channel Agonists; Catechols; Cells, Cultured; Dose-Response Relationship, | 2012 |
A family with discordance between malignant hyperthermia susceptibility and rippling muscle disease.
Topics: Anesthesia; Anesthesia, General; Anesthetics, Inhalation; Caffeine; Caveolin 3; Creatine Kinase; Fam | 2013 |
[Contraction-relaxation coupling of skeletal muscle in patients susceptible to malignant hyperthermia].
Topics: Anesthetics, Inhalation; Halothane; Humans; In Vitro Techniques; Isotonic Contraction; Malignant Hyp | 2002 |
Results of contracture tests with halothane, caffeine, and ryanodine depend on different malignant hyperthermia-associated ryanodine receptor gene mutations.
Topics: Adolescent; Adult; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Child; Chil | 2002 |
Reproducibility of in vitro contracture test results in patients tested for malignant hyperthermia susceptibility.
Topics: Adult; Anesthetics, Inhalation; Biopsy; Caffeine; Disease Susceptibility; Female; Halothane; Humans; | 2002 |
Effects of halothane and isoflurane on the contraction, relaxation and energetics of rat diaphragmatic muscle.
Topics: Anesthetics, Inhalation; Animals; Diaphragm; Energy Metabolism; Halothane; Isoflurane; Isometric Con | 2002 |
"Noninvasive" testing for malignant hyperthermia susceptibility.
Topics: Caffeine; Calcium; Cresols; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Muscl | 2002 |
Patients with malignant hyperthermia demonstrate an altered calcium control mechanism in B lymphocytes.
Topics: Adolescent; Adult; B-Lymphocytes; Caffeine; Calcium; Child; Cresols; Disease Susceptibility; Halotha | 2002 |
Extending the skeletal muscle viability period in the malignant hyperthermia test.
Topics: Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Electric Stimulation; Halothan | 2003 |
Effects of halogenated anaesthetics on diaphragmatic actin-myosin cross-bridge kinetics.
Topics: Actins; Anesthetics, Inhalation; Animals; Culture Techniques; Diaphragm; Halothane; Isoflurane; Musc | 2003 |
Airway contractility and smooth muscle Ca(2+) signaling in lung slices from different mouse strains.
Topics: Acetylcholine; Anesthetics, Inhalation; Animals; Calcium Signaling; Cells, Cultured; Halothane; In V | 2003 |
Detection of a novel ryanodine receptor subtype 1 mutation (R328W) in a malignant hyperthermia family by sequencing of a leukocyte transcript.
Topics: Amino Acid Substitution; Anesthetics, Inhalation; Caffeine; Cell Line; DNA, Complementary; Halothane | 2003 |
STIMULANT ACTIONS OF VOLATILE ANAESTHETICS ON SMOOTH MUSCLE.
Topics: Acetylcholine; Anesthetics; Animals; Anti-Allergic Agents; Central Nervous System Stimulants; Chloro | 1964 |
[THE ACTION OF FLUOTHANE ON THE ISOLATED UTERUS OF THE GUINEA PIG. I].
Topics: Animals; Female; Guinea Pigs; Halothane; Humans; Muscle Contraction; Pharmacology; Pregnancy; Pregna | 1964 |
[ACTION OF FLUOTHANE ON THE ISOLATED UTERUS OF THE GUINEA PIG. II].
Topics: Animals; Electrokymography; Female; Guinea Pigs; Halothane; Humans; Muscle Contraction; Oxytocics; O | 1964 |
Calcium release from sarcoplasmic reticulum is facilitated in human myotubes derived from carriers of the ryanodine receptor type 1 mutations Ile2182Phe and Gly2375Ala.
Topics: Adult; Aged; Caffeine; Calcium; Child; Child, Preschool; Cresols; Female; Genetic Predisposition to | 2003 |
A new mutation in the skeletal ryanodine receptor gene (RYR1) is potentially causative of malignant hyperthermia, central core disease, and severe skeletal malformation.
Topics: Adolescent; Base Sequence; Caffeine; DNA; DNA Mutational Analysis; Dysostoses; Family Health; Female | 2004 |
Genetic testing for malignant hyperthermia in North America.
Topics: Anesthetics, Inhalation; Caffeine; Genetic Testing; Halothane; Humans; Malignant Hyperthermia; Muscl | 2004 |
Similar susceptibility to halothane, caffeine and ryanodine in vitro reflects pharmacogenetic variability of malignant hyperthermia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Biopsy; Caffeine; Central Nervo | 2004 |
Functional characterization of malignant hyperthermia-associated RyR1 mutations in exon 44, using the human myotube model.
Topics: Adolescent; Adult; Aged; Anesthetics; Biopsy; Caffeine; Calcium; Cells, Cultured; Central Nervous Sy | 2004 |
Anesthetics inhibit acetylcholine-promoted guanine nucleotide exchange of heterotrimeric G proteins of airway smooth muscle.
Topics: Acetylcholine; Anesthetics; Anesthetics, Inhalation; Animals; GTP-Binding Protein alpha Subunits, Gs | 2004 |
Comparative analysis of in vitro contracture tests with ryanodine and a combination of ryanodine with either halothane or caffeine: a comparative investigation in malignant hyperthermia.
Topics: Anesthetics, Inhalation; Caffeine; DNA; Halothane; Humans; In Vitro Techniques; Malignant Hypertherm | 2004 |
Malignant hyperthermia: update on susceptibility testing.
Topics: Algorithms; B-Lymphocytes; Biopsy; Caffeine; Disease Susceptibility; DNA Mutational Analysis; Haloth | 2005 |
Inheritance of recurrent exertional rhabdomyolysis in thoroughbreds.
Topics: Anesthetics, Inhalation; Animals; Biopsy; Caffeine; Case-Control Studies; Central Nervous System Sti | 2005 |
Measurement of peripheral muscle resistance in rats with chronic ischemia-induced paraplegia or morphine-induced rigidity using a semi-automated computer-controlled muscle resistance meter.
Topics: Anesthetics, Inhalation; Animals; Baclofen; Chronic Disease; Electromyography; Halothane; Injections | 2005 |
Validity and new malignant hyperthermia diagnostic procedures.
Topics: Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Reproducibility of Results; | 2006 |
Malignant hyperthermia in China.
Topics: Anesthesia, General; Caffeine; China; Halothane; Humans; In Vitro Techniques; Male; Malignant Hypert | 2006 |
Male preponderance of patients testing positive for malignant hyperthermia susceptibility.
Topics: Caffeine; Family; Female; Genetic Predisposition to Disease; Halothane; Humans; Male; Malignant Hype | 2007 |
Fulminant malignant hyperthermia.
Topics: Adult; Anesthetics, General; Caffeine; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contr | 2008 |
Volatile inhalation agents and muscle relaxants in obstetrics.
Topics: Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthetics; Chloroform; Curare; Decamethonium Comp | 1966 |
Clinical pharmacology of ORG NC45 (NorcuronTM): a new nondepolarizing muscle relaxant.
Topics: Adult; Aged; Anesthesia, Inhalation; Halothane; Humans; Middle Aged; Muscle Contraction; Neostigmine | 1981 |
A case of neuroleptic malignant syndrome: in vitro muscle comparison with malignant hyperthermia.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Caffeine; Halothane; Humans; Male; Malignant Hyperthe | 1982 |
Neuroleptic malignant syndrome and malignant hyperthermia.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Caffeine; Fever; Fluphenazine; Halothane; Humans; Musc | 1983 |
Neuromuscular effects of vecuronium (ORG NC45) in infants and children during N2O, halothane anesthesia.
Topics: Adolescent; Adult; Aging; Anesthesia, Inhalation; Child; Child, Preschool; Electromyography; Halotha | 1983 |
Effects of midazolam on directly stimulated muscle biopsies from control and malignant hyperthermia positive patients.
Topics: Anti-Anxiety Agents; Benzodiazepines; Caffeine; Halothane; Humans; In Vitro Techniques; Malignant Hy | 1984 |
The pharmacology of atracurium: a new competitive neuromuscular blocking agent.
Topics: Acid-Base Equilibrium; Animals; Atracurium; Cats; Chickens; Cholinesterase Inhibitors; Dogs; Dose-Re | 1981 |
Maturation of neuromuscular transmission in the infant.
Topics: Child; Child Development; Child, Preschool; Electric Stimulation; Halothane; Humans; Infant; Infant, | 1980 |
Comparative actions of substances affecting cyclic AMP metabolism on the isometric contractions of fast and slow skeletal muscle during single-pulse and subtetanic stimulation.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Aminophylline; Animals; Cyclic AMP; Electric Stimula | 1981 |
Effect of halothane on adenylate kinase in porcine malignant hyperpyrexia.
Topics: Adenosine Monophosphate; Adenylate Kinase; Animals; Disease Models, Animal; Dose-Response Relationsh | 1982 |
Prolonged electromechanical coupling time intervals in skeletal muscle of pigs susceptible to malignant hyperthermia.
Topics: Animals; Caffeine; Disease Models, Animal; Electric Stimulation; Halothane; Kinetics; Malignant Hype | 1983 |
Dantrolene does not block calcium pulse-induced calcium release from a putative calcium channel in sarcoplasmic reticulum from malignant hyperthermia and normal pig muscle.
Topics: Animals; Caffeine; Calcium; Dantrolene; Halothane; Ion Channels; Malignant Hyperthermia; Muscle Cont | 1984 |
Differential effects of halothane on airway nerves and muscle.
Topics: Action Potentials; Animals; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Ha | 1984 |
[Halothane-induced malignant hyperthermia (MH) in the Belgian Landrace breed of pigs: some findings concerning the role of subcellular fractions (author's transl)].
Topics: Animals; Calcium-Transporting ATPases; Cyanides; Halothane; Magnesium; Malignant Hyperthermia; Muscl | 1980 |
Neuromuscular and cardiovascular effects of pancuronium bromide in calves anesthetized with halothane.
Topics: Anesthesia, General; Animals; Blood Pressure; Cardiovascular System; Cattle; Evoked Potentials; Halo | 1984 |
Investigation of malignant hyperthermia in Denmark and Sweden.
Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Child; Creatine Kinase; Disease Susceptibility; Female; G | 1984 |
A protocol for the investigation of malignant hyperpyrexia (MH) susceptibility. The European Malignant Hyperpyrexia Group.
Topics: Biopsy; Caffeine; Disease Susceptibility; Genetic Testing; Halothane; Humans; In Vitro Techniques; M | 1984 |
[Contracture responses of the muscle from a patient with malignant hyperthermia to drugs].
Topics: Adolescent; Diltiazem; Enflurane; Halothane; Humans; In Vitro Techniques; Male; Malignant Hypertherm | 1984 |
Evidence that halothane inhibits norepinephrine release from sympathetic nerve endings in dog saphenous vein by stimulation of presynaptic inhibitory muscarinic receptors.
Topics: Animals; Atropine; Cocaine; Corticosterone; Dogs; Electric Stimulation; Halothane; Muscle Contractio | 1984 |
Inotropic effect of amrinone in rabbit papillary muscle: reversal of the myocardial depressant effect of halothane.
Topics: Aminopyridines; Amrinone; Animals; Anti-Arrhythmia Agents; Electric Stimulation; Halothane; In Vitro | 1984 |
Differential increase in potency of neuromuscular blocking agents by enflurane and halothane.
Topics: Adult; Aged; Anesthesia, Inhalation; Dose-Response Relationship, Drug; Drug Synergism; Enflurane; Fe | 1983 |
[Effects of anesthetics (fluothane and nitrous oxide) and analgesics (diazepam and pentazocine) on the intracystic pressure curves].
Topics: Analgesics; Child; Child, Preschool; Diazepam; Female; Halothane; Humans; Male; Muscle Contraction; | 1983 |
Combined pharmacokinetic and pharmacodynamic study of a single bolus dose of atracurium.
Topics: Adult; Aged; Atracurium; Halothane; Humans; Injections, Intravenous; Isoquinolines; Kinetics; Middle | 1983 |
Modification of atracurium blockade by halothane and by suxamethonium. A review of clinical experience.
Topics: Adolescent; Adult; Anesthesia, General; Atracurium; Drug Interactions; Halothane; Humans; Isoquinoli | 1983 |
Halothane-succinylcholine induced masseter spasm: indicative of malignant hyperthermia susceptibility?
Topics: Caffeine; Child; Child, Preschool; Creatine Kinase; Female; Halothane; Humans; Male; Malignant Hyper | 1984 |
Interaction of halothane and aminophylline on the isolated hemidiaphragm of the rat.
Topics: Aminophylline; Animals; Diaphragm; Drug Interactions; Edetic Acid; Electric Stimulation; Epinephrine | 1980 |
In vivo and in vitro responses to magnesium sulphate in porcine malignant hyperthermia.
Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Contracture; Halo | 1980 |
In vitro contracture tests for susceptibility to malignant hyperthermia.
Topics: Caffeine; Disease Susceptibility; Drug Interactions; Halothane; Humans; Malignant Hyperthermia; Musc | 1983 |
Spectrum of susceptibility to malignant hyperthermia--diagnostic dilemma.
Topics: Animals; Body Temperature; Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; | 1983 |
Is theophylline, aminophylline, or caffeine (methylxanthines) contraindicated in malignant hyperthermia susceptible patients?
Topics: Adolescent; Adult; Aminophylline; Caffeine; Child; Halothane; Humans; In Vitro Techniques; Male; Mal | 1983 |
Mechanical responses to peroneal nerve stimulation in halothane-anesthetized horses in the absence of neuromuscular blockade and during partial nondepolarizing blockade.
Topics: Anesthesia; Animals; Cats; Edrophonium; Electric Stimulation; Gallamine Triethiodide; Halothane; Hor | 1983 |
Cumulative dose responses to gallamine, pancuronium, and neostigmine in halothane-anesthetized horses: neuromuscular and cardiovascular effects.
Topics: Anesthesia; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Female; Gallamine Triet | 1983 |
The control of muscle contracture by the action of dantrolene on the sarcolemma.
Topics: Animals; Caffeine; Dantrolene; Diaphragm; Dinitrophenols; Dose-Response Relationship, Drug; Halothan | 1983 |
Screening for malignant hyperthermia susceptibility.
Topics: Caffeine; Dantrolene; Halothane; Humans; Malignant Hyperthermia; Mass Screening; Muscle Contraction; | 1980 |
[Malignant hyperthermia-results of familial investigations in Austria (author's transl)].
Topics: Adenosine Triphosphate; Austria; Caffeine; Calcium; Chlorpromazine; Creatine Kinase; Halothane; Huma | 1981 |
Mechanical properties of normal and malignant hyperthemia susceptible porcine muscle: effects of halothane and other drugs.
Topics: Animals; Anura; Caffeine; Drug Interactions; Epinephrine; Halothane; In Vitro Techniques; Male; Mali | 1980 |
Masseter spasm induced by succinylcholine in children: contracture testing for malignant hyperthermia: report of six cases.
Topics: Anesthesia; Caffeine; Child; Child, Preschool; Halothane; Humans; Male; Malignant Hyperthermia; Mass | 1982 |
Tachyphylaxis after repeated dosage of decamethonium in anaesthetized man.
Topics: Anesthesia; Decamethonium Compounds; Halothane; Humans; Muscle Contraction; Neostigmine; Tachyphylax | 1982 |
Cellular membrane potentials and contractile threshold in mammalian skeletal muscle susceptible to malignant hyperthermia.
Topics: Animals; Dose-Response Relationship, Drug; Halothane; Malignant Hyperthermia; Membrane Potentials; M | 1982 |
The in-vitro caffeine contracture test: influence of the muscle histochemical profile on test results.
Topics: Animals; Caffeine; Halothane; Histocytochemistry; Male; Malignant Hyperthermia; Muscle Contraction; | 1982 |
Edrophonium: duration of action and atropine requirement in humans during halothane anesthesia.
Topics: Anesthesia, General; Arrhythmias, Cardiac; Atropine; Blood Pressure; Dose-Response Relationship, Dru | 1982 |
Pharmacological in-vitro studies in malignant hyperthermia in childhood.
Topics: Adolescent; Biopsy; Caffeine; Child; Child, Preschool; Dose-Response Relationship, Drug; Halothane; | 1982 |
Effects of inhalation anaesthetic agents on the electrical and mechanical activity of the rat duodenum.
Topics: Action Potentials; Anesthesia, Inhalation; Animals; Duodenum; Enflurane; Ether; Ethyl Ethers; Gastro | 1982 |
Comparison of the caffeine skinned fibre tension (CSFT) test with the caffeine-halothane contracture (CHC) test in the diagnosis of malignant hyperthermia.
Topics: Anesthesia; Caffeine; Calcium; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscl | 1982 |
Human malignant hyperthermia: awake episodes and correction by dantrolene.
Topics: Adenosine Triphosphate; Adult; Caffeine; Dantrolene; Fatigue; Female; Halothane; Humans; In Vitro Te | 1980 |
Effects of halothane on functionally skinned rabbit soleus muscle fibers: a correlation between tension transient and 45Ca release.
Topics: Animals; Caffeine; Calcium; Calcium Radioisotopes; Halothane; Muscle Contraction; Muscle Proteins; M | 1980 |
[Halothane and spontaneous motility of human taenia libera in vitro (author's transl)].
Topics: Gastrointestinal Motility; Halothane; Humans; In Vitro Techniques; Intestine, Large; Muscle Contract | 1981 |
Temperature dependence of muscle function in malignant hyperpyrexia-susceptible swine.
Topics: Animals; Caffeine; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Potas | 1981 |
Effect of temperature, time and fascicle size on the caffeine contracture test.
Topics: Caffeine; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Techniques; Malignant Hypert | 1980 |
Contracture responses and energy stores in quadriceps muscle from humans age 7-82 years.
Topics: Adolescent; Adult; Aged; Aging; Caffeine; Child; Energy Metabolism; Halothane; Humans; Middle Aged; | 1980 |
Effects of temperature, adenosine triphosphate and magnesium concentrations on the contraction of actomyosin isolated from halothane-sensitive and -insensitive German Landrace pigs.
Topics: Actomyosin; Adenosine Triphosphate; Animals; Calcium; Halothane; Magnesium; Malignant Hyperthermia; | 1980 |
Neuromuscular blockade by neostigmine in anaesthetized man.
Topics: Anesthesia, General; Drug Interactions; Drug Synergism; Gallamine Triethiodide; Halothane; Humans; M | 1980 |
Site of the muscle cell abnormality in swine susceptible to malignant hyperpyrexia.
Topics: Acetylcholine; Animals; Caffeine; Dantrolene; Halothane; In Vitro Techniques; Malignant Hyperthermia | 1980 |
Evaluation of atracurium in anaesthetized man.
Topics: Adult; Aged; Anesthesia, General; Atracurium; Drug Administration Schedule; Drug Evaluation; Halotha | 1981 |
E.E.G. activity during halothane anaesthesia in man.
Topics: Adolescent; Adult; Anesthesia, Inhalation; Child; Child, Preschool; Dermatologic Surgical Procedures | 1981 |
Characterization of the methylxanthine-induced propagated wave phenomenon in striated muscle.
Topics: Animals; Caffeine; Chick Embryo; Halothane; Histocytochemistry; Muscle Contraction; Muscles; Quinine | 1980 |
Genotype and phenotype relationships for mutations in the ryanodine receptor in patients referred for diagnosis of malignant hyperthermia.
Topics: Anesthetics, Inhalation; Caffeine; Calcium Channels; Central Nervous System Stimulants; DNA Mutation | 1995 |
Effects of preslaughter muscle exercise on muscle metabolism and meat quality studied in anesthetized pigs of different halothane genotypes.
Topics: Animals; Crosses, Genetic; Electric Stimulation; Energy Metabolism; Genotype; Glycogen; Halothane; H | 1995 |
Low-dose halothane produces airway dilatation but does not alter parenchymal mechanics in the normal canine lung.
Topics: Airway Resistance; Algorithms; Animals; Bronchi; Bronchodilator Agents; Dogs; Elasticity; Forced Exp | 1995 |
C1840-T mutation in the human skeletal muscle ryanodine receptor gene: frequency in northern German families susceptible to malignant hyperthermia and the relationship to in vitro contracture response.
Topics: Adolescent; Adult; Aged; Base Sequence; Caffeine; Calcium Channels; Child; Child, Preschool; Chromos | 1995 |
Effect of different volatile anaesthetics on suxamethonium-induced jaw muscle contracture in rats.
Topics: Anesthetics; Animals; Desflurane; Halothane; Hot Temperature; Isoflurane; Male; Masticatory Muscles; | 1995 |
Effect of phenytoin on skeletal muscle from quarter horses with hyperkalaemic periodic paralysis.
Topics: Animals; Caffeine; Calcium; Halothane; Horse Diseases; Horses; Hyperkalemia; Muscle Contraction; Mus | 1995 |
Effects of halothane and isoflurane on cytosolic calcium ion concentrations and contraction in the vascular smooth muscle of the rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
The effect of calcium channel antagonists and BAY K 8644 on calcium fluxes of malignant hyperpyrexia-susceptible muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
Malignant hyperthermia: halothane- and calcium-induced calcium release in skeletal muscle.
Topics: Animals; Calcium; Halothane; Horses; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Con | 1993 |
Factors influencing the direct actions of volatile anesthetics on airway smooth muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Dogs; | 1993 |
The effect of anesthesia on abdominal muscle resting length and shortening in awake dogs.
Topics: Abdominal Muscles; Anesthesia, General; Animals; Dogs; Electrodes, Implanted; Electromyography; Fema | 1995 |
Effect of cocaine on the contracture response to 1% halothane in patients undergoing diagnostic muscle biopsy for malignant hyperthermia.
Topics: Adult; Biopsy; Caffeine; Cocaine; Contracture; Disease Susceptibility; Female; Halothane; Humans; Ma | 1995 |
Exercise induced hyperthermia in a racing greyhound.
Topics: Animals; Caffeine; Dog Diseases; Dogs; Exercise Test; Halothane; In Vitro Techniques; Male; Malignan | 1994 |
Volatile anesthetic actions on contractile proteins in membrane-permeabilized small mesenteric arteries.
Topics: Animals; Calcium; Cell Membrane Permeability; Contractile Proteins; Enflurane; Escin; Halothane; In | 1995 |
Inhibitory effects of halothane on high(K+)-induced canine tracheal smooth muscle contraction and intracellular Ca2+ increment.
Topics: Animals; Calcium; Dogs; Halothane; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Potassiu | 1994 |
Mivacurium-induced neuromuscular blockade during sevoflurane and halothane anaesthesia in children.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Child, Preschool | 1995 |
Gasoline vapors induce severe rhabdomyolysis.
Topics: Adult; Alcohol Drinking; Automobile Driving; Caffeine; Creatine Kinase; Gasoline; Halothane; Humans; | 1994 |
Genetic effects on the variability of the halothane and caffeine muscle contracture tests.
Topics: Adult; Biopsy; Caffeine; Child; Disease Susceptibility; Family; Fatal Outcome; Female; Halothane; Hu | 1994 |
[Effects of sevoflurane or halothane on contractile responses of isolated canine basilar artery].
Topics: Animals; Basilar Artery; Dogs; Ethers; Halothane; In Vitro Techniques; Methyl Ethers; Muscle Contrac | 1994 |
Volatile anesthetics and agonist-induced contractions in porcine coronary artery smooth muscle and Ca2+ mobilization in cultured immortalized vascular smooth muscle cells.
Topics: Aluminum Compounds; Animals; Calcium; Cells, Cultured; Coronary Vessels; Dose-Response Relationship, | 1994 |
The effects of benzamil on in vitro contracture responses of human skeletal muscle to halothane.
Topics: Amiloride; Drug Interactions; Halothane; Humans; In Vitro Techniques; Kinetics; Malignant Hypertherm | 1994 |
Volatile anesthetics decrease peristalsis in the guinea pig ureter.
Topics: Animals; Dose-Response Relationship, Drug; Enflurane; Guinea Pigs; Halothane; In Vitro Techniques; I | 1994 |
Relationship between post-tetanic twitch and single twitch response after administration of vecuronium.
Topics: Adult; Anesthesia, Inhalation; Anesthetics; Enflurane; Ethers; Female; Halothane; Humans; Isoflurane | 1993 |
Viability criterion of muscle bundles used in the in vitro contracture test in patients with neuromuscular diseases.
Topics: Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Me | 1994 |
Effects of halothane on the relationship between cytosolic calcium and force in airway smooth muscle.
Topics: Acetylcholine; Animals; Calcium; Cytosol; Dogs; Female; Halothane; In Vitro Techniques; Male; Muscle | 1994 |
Role of intracellular Ca2+ pools in the effects of halothane and isoflurane on vascular smooth muscle contraction.
Topics: Animals; Calcium; Halothane; In Vitro Techniques; Ion Transport; Isoflurane; Male; Muscle Contractio | 1994 |
Halothane and temperature interact to increase succinylcholine-induced jaw contracture in the rat.
Topics: Animals; Body Temperature; Calcium; Halothane; Jaw; Male; Muscle Contraction; Rats; Rats, Inbred Lew | 1993 |
Halothane and pertussis toxin-sensitive G proteins in airway smooth muscle.
Topics: Acetylcholine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Depression, Chemical; Dogs; Drug | 1994 |
Inhibitory effects of four inhaled anesthetics on canine tracheal smooth muscle contraction and intracellular Ca2+ concentration.
Topics: Anesthetics; Animals; Calcium; Carbachol; Dogs; Drug Interactions; Enflurane; Ethers; Halothane; Iso | 1993 |
Combined caffeine-halothane test for malignant hyperthermia.
Topics: Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction | 1993 |
Halothane alters cytosolic calcium transient in tracheal smooth muscle.
Topics: Acetylcholine; Aequorin; Animals; Calcium; Cytosol; Dogs; Electrophysiology; Halothane; In Vitro Tec | 1993 |
False-negative results with muscle caffeine halothane contracture testing for malignant hyperthermia.
Topics: Adolescent; Adult; Biopsy; Caffeine; Child, Preschool; False Negative Reactions; Female; Halothane; | 1993 |
Phenotypes associated with malignant hyperthermia susceptibility in swine genotyped as homozygous or heterozygous for the ryanodine receptor mutation.
Topics: Animals; Base Sequence; Calcium; Calcium Channels; Disease Susceptibility; Genotype; Halothane; Hete | 1993 |
In vitro effect of ephedrine, adrenaline, noradrenaline and isoprenaline on halothane-induced contractures in skeletal muscle from patients potentially susceptible to malignant hyperthermia.
Topics: Dose-Response Relationship, Drug; Drug Synergism; Ephedrine; Epinephrine; Halothane; Humans; In Vitr | 1993 |
Caffeine contractures, twitch characteristics and the threshold for Ca(2+)-induced Ca2+ release in skeletal muscle from horses with chronic intermittent rhabdomyolysis.
Topics: Animals; Caffeine; Calcium; Female; Halothane; Horse Diseases; Horses; In Vitro Techniques; Male; Mu | 1993 |
Altered release and metabolism of norepinephrine in superfused canine saphenous veins in the presence of halothane and hypoxia.
Topics: Animals; Dogs; Electric Stimulation; Female; Halothane; Hypoxia; Male; Methoxyhydroxyphenylglycol; M | 1993 |
Improved noninvasive diagnostic testing for malignant hyperthermia susceptibility from a combination of metabolites determined in vivo with 31P-magnetic resonance spectroscopy.
Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Disease Susceptibility; Female; Halothane; Humans; Magnet | 1993 |
Neuromuscular blockade by use of atracurium in anesthetized llamas.
Topics: Analysis of Variance; Anesthesia, General; Animals; Atracurium; Blood Pressure; Camelids, New World; | 1993 |
Comparison of in vitro contracture testing with ryanodine, halothane and caffeine in malignant hyperthermia and other neuromuscular disorders.
Topics: Caffeine; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Tech | 1993 |
Interaction of gentamycin and atracurium in anaesthetised horses.
Topics: Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Atracurium; Drug Interactions; Drug Synergi | 1994 |
On the nature of the link between malignant hyperthermia and exertional heatstroke.
Topics: Animals; Body Temperature Regulation; Caffeine; Calcium Channels; Disease Models, Animal; Disease Su | 1995 |
Comparison of the segregation of the RYR1 C1840T mutation with segregation of the caffeine/halothane contracture test results for malignant hyperthermia susceptibility in a large Manitoba Mennonite family.
Topics: Anesthetics, Inhalation; Caffeine; Disease Susceptibility; Female; Halothane; Heterozygote; Humans; | 1996 |
Effect of halothane on phenylephrine-induced vascular smooth muscle contractions in endotoxin-exposed rat aortic rings.
Topics: Anesthetics, Inhalation; Animals; Aorta, Thoracic; Arginine; Disease Models, Animal; Dose-Response R | 1996 |
Effects of halothane and isoflurane on antigen- and leukotriene-D4-induced constriction of guinea pig trachea.
Topics: Anesthetics, Inhalation; Animals; Guinea Pigs; Halothane; In Vitro Techniques; Isoflurane; Leukotrie | 1995 |
Isoform-dependent effects of halothane in human skinned striated fibers.
Topics: Anesthetics, Inhalation; Calcium; Halothane; Humans; In Vitro Techniques; Muscle Contraction; Muscle | 1996 |
Effects of the serotonin2 receptor agonist DOI on skeletal muscle specimens from malignant hyperthermia-susceptible patients.
Topics: Adolescent; Adult; Aged; Amphetamines; Animals; Cattle; Child; Child, Preschool; Halothane; Humans; | 1996 |
Pharmacokinetics of rocuronium after bolus and continuous infusion during halothane anaesthesia.
Topics: Adolescent; Adult; Androstanols; Anesthesia, Inhalation; Anesthetics, Inhalation; Female; Halothane; | 1996 |
Malignant hyperthermia (MH) diagnostics: a comparison between the halothane-caffeine- and the ryanodine-contracture-test results in MH susceptible, normal and control muscle.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Child; Halothane; Humans; In Vitro Techn | 1996 |
Altered sodium current response to intracellular fatty acids in halothane-hypersensitive skeletal muscle.
Topics: Aging; Disease Susceptibility; Electric Conductivity; Fatty Acids; Halothane; Humans; Intracellular | 1996 |
Guinea-pig tracheal responsiveness in vitro following general anaesthesia with halothane.
Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Guinea Pigs; Halothane; In Vitro Techniques; | 1996 |
Malignant hyperthermia.
Topics: Anesthesia, General; Caffeine; Counseling; Disease Susceptibility; Halothane; Humans; Malignant Hype | 1996 |
Inferior pharyngeal constrictor electromyographic activity during permeability pulmonary edema in lambs.
Topics: Anesthetics, General; Animals; Animals, Newborn; Blood Gas Analysis; Electromyography; Glottis; Halo | 1996 |
[Are monamine oxidase inhibitors in disposition to malignant hyperthermia contraindicated? Discussion based on a case report].
Topics: Anesthetics, Inhalation; Attention Deficit Disorder with Hyperactivity; Benzamides; Child; Contraind | 1996 |
Halothane counteracts acetylcholine-induced increase in Ca2+ sensitivity of the contractile apparatus in airway smooth muscle.
Topics: Acetylcholine; Animals; Calcium; Dose-Response Relationship, Drug; Halothane; Muscle Contraction; Mu | 1996 |
Reduced Mg2+ inhibition of Ca2+ release in muscle fibers of pigs susceptible to malignant hyperthermia.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Dantrolene; Genetic Predisposition to Disease; | 1997 |
Malignant hyperthermia testing in patients with persistently increased serum creatine kinase levels.
Topics: Adolescent; Adult; Anesthetics, Inhalation; Biopsy, Needle; Caffeine; Child; Child, Preschool; Clini | 1997 |
Recombination between the postulated CCD/MHE/MHS locus and RYR1 gene markers.
Topics: Alleles; Caffeine; Calcium Channels; Child, Preschool; Chromosomes, Human, Pair 19; Female; Genetic | 1996 |
The effects of halothane pretreatment on manganese influx induced by muscarinic stimulation of airway smooth muscle.
Topics: Acetylcholine; Anesthetics, Inhalation; Animals; Calcium; Cholinergic Agents; Dogs; Female; Fura-2; | 1997 |
Effect of temperature variation (22 degrees C-44 degrees C) on halothane and caffeine contracture testing in normal humans.
Topics: Aged; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Halothane; Humans; In Vi | 1997 |
Classification of malignant hyperthermia-equivocal patients by 4-chloro-M-cresol.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Cresols; Disease Susceptibility; Dose-Re | 1997 |
Malignant hyperthermia susceptibility, an autosomal dominant disorder?
Topics: Adolescent; Adult; Caffeine; Calcium Channels; Child; Child, Preschool; Female; Genes, Dominant; Gen | 1997 |
[Effect of chlorocresol vs caffeine on muscle contracture in malignant hyperthermia susceptible patients].
Topics: Adolescent; Adult; Caffeine; Cresols; Disease Susceptibility; Halothane; Humans; In Vitro Techniques | 1997 |
Dystrophin deficient mdx muscle is not prone to MH susceptibility: an in vitro study.
Topics: Anesthetics, Inhalation; Animals; Caffeine; Disease Susceptibility; Dystrophin; Halothane; Male; Mal | 1997 |
In vitro contracture test for diagnosis of malignant hyperthermia following the protocol of the European MH Group: results of testing patients surviving fulminant MH and unrelated low-risk subjects. The European Malignant Hyperthermia Group.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia; Biopsy; Caffeine; Child; Child, Preschool; F | 1997 |
4-Chloro-m-cresol test--a possible supplementary test for diagnosis of malignant hyperthermia susceptibility.
Topics: Biopsy; Caffeine; Cresols; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Huma | 1997 |
Reduced inhibitory effect of Mg2+ on ryanodine receptor-Ca2+ release channels in malignant hyperthermia.
Topics: Animals; Binding Sites; Biophysical Phenomena; Biophysics; Caffeine; Calcium; Halothane; Humans; In | 1997 |
Effects of high-dose gentamicin sulfate on neuromuscular blockade in halothane-anesthetized horses.
Topics: Analysis of Variance; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Anti-Bacterial Agent | 1997 |
Histological support for the difference between malignant hyperthermia susceptible (MHS), equivocal (MHE) and negative (MHN) muscle biopsies.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Atrophy; Biopsy; Disease Susceptibility; Female; H | 1997 |
The Israeli Diagnostic Center for Malignant Hyperthermia: 7-years' accumulated experience.
Topics: Academies and Institutes; Adult; Aged; Biopsy; Caffeine; Child; Electromyography; Female; Genetic Pr | 1997 |
The effects of the atypical antipsychotics clozapine, remoxipride and risperidone on the contractile characteristics of rat skeletal muscle in vitro.
Topics: Animals; Antipsychotic Agents; Caffeine; Clozapine; Dantrolene; Dose-Response Relationship, Drug; Dr | 1997 |
The effect of halothane and sevoflurane on fatigue-induced changes in hamster diaphragmatic contractility.
Topics: Anesthetics, Inhalation; Animals; Cricetinae; Diaphragm; Ethers; Halothane; In Vitro Techniques; Mal | 1998 |
Antagonism of atracurium-induced block in obese patients.
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Atracurium; Body Mass Index; Body Weight; | 1998 |
Effects of veratridine on mechanical responses of human malignant hyperthermic muscle fibers.
Topics: Calcium; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Sodium | 1998 |
Discordance between malignant hyperthermia susceptibility and RYR1 mutation C1840T in two Scandinavian MH families exhibiting this mutation.
Topics: Anesthesia; Caffeine; Denmark; Female; Genetic Predisposition to Disease; Halothane; Humans; Male; M | 1997 |
Rhabdomyolysis after infection and taking a cold medicine in a patient who was susceptible to malignant hyperthermia.
Topics: Adult; Caffeine; Chlorpheniramine; Common Cold; Dantrolene; Halothane; Humans; In Vitro Techniques; | 1998 |
Effects of cisatracurium in children during halothane-nitrous oxide anesthesia.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Antidotes; Atracurium; | 1998 |
Rhabdomyolysis following severe physical exercise in a patient with predisposition to malignant hyperthermia.
Topics: Adult; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Disease Susceptibility; | 1998 |
New equipment for neuromuscular transmission monitoring: a comparison of the TOF-Guard with the Myograph 2000.
Topics: Acceleration; Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhal | 1998 |
Role of intracellular Ca2+ stores in the inhibitory effect of halothane on airway smooth muscle contraction.
Topics: Anesthetics, Inhalation; Animals; Calcium; Dogs; Halothane; Inositol 1,4,5-Trisphosphate; Muscle Con | 1998 |
Drug-specific effects of volatile anesthetics on Ca2+ sensitization in airway smooth muscle.
Topics: Acetylcholine; Anesthetics, Inhalation; Animals; Calcium; Dogs; Escin; Female; Guanosine Triphosphat | 1998 |
Treatment of normal skeletal muscle with FK506 or rapamycin results in halothane-induced muscle contracture.
Topics: Adolescent; Adult; Anesthetics, Inhalation; Calcium; Carrier Proteins; Child; Child, Preschool; DNA- | 1998 |
Effects of halothane and isoflurane on beta-adrenoceptor-mediated responses in the vascular smooth muscle of rat aorta.
Topics: Adrenergic beta-Agonists; Anesthetics, Inhalation; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; | 1998 |
Complex formation of skeletal muscle Ca2+-regulatory membrane proteins by halothane.
Topics: Anesthetics, Inhalation; Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Calsequestrin | 1999 |
Halothane induces calcium release from human skinned masseter muscle fibers.
Topics: Adult; Anesthetics, Inhalation; Calcium; Female; Halothane; Humans; Male; Masseter Muscle; Muscle Co | 1999 |
ATX II, a sodium channel toxin, sensitizes skeletal muscle to halothane, caffeine, and ryanodine.
Topics: Animals; Caffeine; Cnidarian Venoms; Female; Halothane; Humans; Male; Malignant Hyperthermia; Muscle | 1999 |
Comparison between the European and North American protocols for diagnosis of malignant hyperthermia susceptibility in humans.
Topics: Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Sensitivity and Specificity | 1999 |
Effects of halothane on mechanical response of skeletal muscle from malignant hyperthermia susceptible patients.
Topics: Anesthetics, Inhalation; Biopsy; Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techn | 1998 |
Abnormal regulation of muscle contraction in horses with recurrent exertional rhabdomyolysis.
Topics: Anesthetics, Inhalation; Animals; Biopsy; Caffeine; Central Nervous System Stimulants; Female; Halot | 1999 |
Caffeine- or halothane-induced contractures of masseter muscle are similar to those of vastus muscle in normal humans.
Topics: Aged; Aged, 80 and over; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Contr | 1999 |
Factors predicting atracurium reversal time.
Topics: Adult; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Atracurium; Ch | 1999 |
5-HT2 receptor antagonist-mediated inhibition of halothane-induced contractures in skeletal muscle specimens from malignant hyperthermia susceptible patients.
Topics: Adolescent; Adult; Anesthetics, Inhalation; Caffeine; Child; Dose-Response Relationship, Drug; Drug | 1999 |
Halothane attenuates myogenicity in the rabbit ear artery.
Topics: Anesthetics, Inhalation; Animals; Arteries; Dose-Response Relationship, Drug; Ear; Female; Halothane | 1999 |
Halothane decreases calcium sensitivity of rat aortic smooth muscle.
Topics: Anesthetics, Inhalation; Animals; Aorta, Thoracic; Calcium; Cytosol; Dinoprost; Fluorescent Dyes; Fu | 1999 |
Comparative contractile effects of halothane and sevoflurane in rat aorta.
Topics: Anesthetics, Inhalation; Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Drug Interacti | 2000 |
Relaxation by sevoflurane, desflurane and halothane in the isolated guinea-pig trachea via inhibition of cholinergic neurotransmission.
Topics: Acetylcholine; Anesthetics, Inhalation; Animals; Cholinergic Fibers; Culture Techniques; Desflurane; | 1999 |
Shortening velocity of skeletal muscle from humans with malignant hyperthermia susceptibility: effects of halothane.
Topics: Anesthetics, Inhalation; Biomechanical Phenomena; Halothane; Humans; In Vitro Techniques; Kinetics; | 2000 |
FK506 (tacrolimus) increases halothane-induced Ca2+ release from skeletal muscle sarcoplasmic reticulum.
Topics: Anesthetics, Inhalation; Animals; Calcium; Drug Synergism; Halothane; Immunophilins; Immunosuppressi | 2000 |
Remote arteriolar dilations in response to muscle contraction under capillaries.
Topics: Animals; Arterioles; Capillaries; Cricetinae; Enzyme Inhibitors; Gap Junctions; Glycyrrhetinic Acid; | 2000 |
In vivo whole-body resting energy expenditure and insulin action in human malignant hyperthermia.
Topics: Adult; Anesthetics, Inhalation; Basal Metabolism; Body Composition; Caffeine; Calorimetry, Indirect; | 2000 |
Between-center variability of results of the in vitro contracture test for malignant hyperthermia susceptibility.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Biopsy; Caffeine; Female; Genetic Predisposition t | 2000 |
Inositol 1,4,5-trisphosphate synthesis in mononuclear white blood cells of malignant hyperthermia-susceptible and normal human beings, following in vitro exposure to halothane, caffeine and ryanodine.
Topics: Anesthetics, Inhalation; Caffeine; Cell Separation; Halothane; Humans; In Vitro Techniques; Inositol | 2000 |
Local and remote arteriolar dilations initiated by skeletal muscle contraction.
Topics: Animals; Arterioles; Cricetinae; Electric Stimulation; Gap Junctions; Glycyrrhetinic Acid; Halothane | 2000 |
Xenon does not induce contracture in human malignant hyperthermia muscle.
Topics: Anesthetics, Inhalation; Caffeine; Culture Techniques; Dose-Response Relationship, Drug; Drug Evalua | 2000 |
Evidence for susceptibility to malignant hyperthermia in patients with exercise-induced rhabdomyolysis.
Topics: Adolescent; Adult; Anesthetics, Inhalation; Case-Control Studies; Child; Disease Susceptibility; Exe | 2001 |
Homozygous and heterozygous Arg614Cys mutations (1840C-->T) in the ryanodine receptor gene co-segregate with malignant hyperthermia susceptibility in a German family.
Topics: Adult; Anesthetics, Inhalation; Caffeine; DNA Mutational Analysis; Female; Genetic Predisposition to | 2001 |
A noninvasive investigation of muscle energetics supports similarities between exertional heat stroke and malignant hyperthermia.
Topics: Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Energy Metabolism; Halothane; | 2001 |
Prolonging viability of swine muscle biopsy specimens in malignant hyperthermia testing.
Topics: Anesthetics, Inhalation; Animals; Caffeine; Central Nervous System Stimulants; Cold Temperature; Ele | 2001 |
Congenital myopathy with central cores and fingerprint bodies in association with malignant hyperthermia susceptibility.
Topics: Adult; Anesthetics, Inhalation; Biopsy; Caffeine; Central Nervous System Stimulants; Halothane; Huma | 2001 |
Determination of a positive malignant hyperthermia (MH) disposition without the in vitro contracture test in families carrying the RYR1 Arg614Cys mutation.
Topics: Caffeine; DNA; DNA Mutational Analysis; Family Health; Female; Halothane; Humans; Male; Malignant Hy | 2001 |
Autosomal dominant canine malignant hyperthermia is caused by a mutation in the gene encoding the skeletal muscle calcium release channel (RYR1).
Topics: Amino Acid Sequence; Animals; Dog Diseases; Dogs; Female; Genotype; Halothane; In Vitro Techniques; | 2001 |
Halothane inhibits contraction and action potential duration to a greater extent in subendocardial than subepicardial myocytes from the rat left ventricle.
Topics: Action Potentials; Anesthetics, Inhalation; Animals; Cells, Cultured; Electric Stimulation; Halothan | 2001 |
Halothane differentially decreases 5-hydroxytryptamine-induced contractions in normal and chronic hypoxic rat pulmonary arteries.
Topics: Anesthetics, Inhalation; Animals; Cadmium; Calcium Channel Blockers; Chronic Disease; Halothane; Hyp | 2001 |
Testing for malignant hyperthermia.
Topics: Anesthesia; Biopsy; Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Sensiti | 2002 |
The differential effect of halothane and 1,2-dichlorohexafluorocyclobutane on in vitro muscle contractures of patients susceptible to malignant hyperthermia.
Topics: Adult; Aged; Anesthetics; Anesthetics, Inhalation; Chlorofluorocarbons; Cyclobutanes; Female; Geneti | 2002 |
Mutation screening in the ryanodine receptor 1 gene (RYR1) in patients susceptible to malignant hyperthermia who show definite IVCT results: identification of three novel mutations.
Topics: Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Genetic Testing; Halothane; Hu | 2002 |
'Picture frame' fibres in a carrier of the trait for malignant hyperpyrexia.
Topics: Adenosine Triphosphatases; Adult; Calcium; Halothane; Heterozygote; Histocytochemistry; Humans; Hydr | 1975 |
Effects of volatile anesthetics on directly and indirectly stimulated skeletal muscle.
Topics: Anesthetics; Animals; Electric Stimulation; Enflurane; Ether; Ethers; Guinea Pigs; Halothane; In Vit | 1979 |
Letter: Malignant hyperpyrexia.
Topics: Acidosis; Calcium; Catecholamines; Halothane; Humans; Insulin; Insulin Secretion; Malignant Hyperthe | 1975 |
Isometric contraction of skeletal muscle of malignant hyperthermia (MH) susceptible and resistant Belgian landrace pigs under the influence of several drugs.
Topics: Animals; Caffeine; Halothane; Hypothermia; Hypothermia, Induced; In Vitro Techniques; Muscle Contrac | 1978 |
Some characteristics of neuromuscular block in the respiratory musculature in anaesthetized man.
Topics: Abdominal Muscles; Adult; Diaphragm; Dose-Response Relationship, Drug; Halothane; Humans; Intercosta | 1976 |
Iteraction of halothane with non-depolarizing neuromuscular blocking drugs in man [proceedings].
Topics: Drug Interactions; Gallamine Triethiodide; Halothane; Humans; Muscle Contraction; Neuromuscular Nond | 1977 |
Interaction of halothane with non-depolarizing neuromuscular blocking drugs in man.
Topics: Anesthesia; Atropine; Drug Interactions; Gallamine Triethiodide; Halothane; Humans; Muscle Contracti | 1979 |
Vascular responses to anaesthetic agents.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics; Animals; Aorta; Aorta, Thora | 1975 |
Rationale for dantrolene vs. procainamide for treatment of malignant hyperthermia.
Topics: Animals; Dantrolene; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Halothane; Hy | 1979 |
Sites and mechanisms of action of halothane on skeletal muscle function in vitro.
Topics: Animals; Caffeine; Diaphragm; Dose-Response Relationship, Drug; Glycerol; Halothane; Male; Muscle Co | 1979 |
Identification of susceptibility to malignant hyperpyrexia in swine.
Topics: Animals; Caffeine; Disease Models, Animal; Dose-Response Relationship, Drug; Halothane; In Vitro Tec | 1979 |
Effect of halothane on isometric contractile properties of muscle from stress-susceptible and stress-resistant pigs.
Topics: Animals; Halothane; Muscle Contraction; Stress, Physiological; Swine; Swine Diseases | 1979 |
Does prior dantrolene affect the in vitro diagnosis of malignant hyperthermia susceptibility?
Topics: Animals; Biopsy; Caffeine; Dantrolene; Drug Interactions; Halothane; In Vitro Techniques; Malignant | 1979 |
Malignant hyperthermia: diagnosis, treatment and investigations of a skeletal muscle lesion.
Topics: Anesthetics; Animals; Caffeine; Diagnosis, Differential; Disease Models, Animal; Halothane; Humans; | 1979 |
Is malignant hyperpyrexia muscle denervated?
Topics: Animals; Caffeine; Calcium; Evoked Potentials; Female; Halothane; Humans; In Vitro Techniques; Membr | 1977 |
Effects of end-tidal concentrations of cyclopropane, halothane and diethyl ether on peripheral autonomic neuroeffector systems in the rat.
Topics: Animals; Autonomic Nervous System; Blood Pressure; Cyclopropanes; Dose-Response Relationship, Drug; | 1978 |
Enflurane, isoflurane, and halothane and isolated human uterine muscle.
Topics: Adult; Depression, Chemical; Enflurane; Female; Halothane; Humans; Isoflurane; Methyl Ethers; Muscle | 1977 |
Screening for malignant hyperpyrexia.
Topics: Caffeine; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Techniques; Malignant Hypert | 1977 |
Intrapulmonary receptors in the Tegu lizard: II. Functional characteristics and localization;.
Topics: Acetazolamide; Animals; Carbon Dioxide; Chemoreceptor Cells; Electric Stimulation; Electrophysiology | 1977 |
Effect of halothane on tensions developed by in vitro preparations of normal human skeletal muscle [proceedings].
Topics: Halothane; Humans; In Vitro Techniques; Muscle Contraction; Muscles | 1977 |
Anaesthesia for patients susceptible to malignant hyperpyrexia. A study of pancuronium and methylprednisolone.
Topics: Anesthesia; Contracture; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Techniques; M | 1977 |
The adenosine triphosphate (ATP) depletion test: comparison with the caffeine contracture test as a method of diagnosing malignant hyperthermia susceptibility.
Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Biopsy; Caffeine; Carbon Dioxide; Child; Dose-Respo | 1976 |
[Malignant hyperthermia in Belgian landrace pigs].
Topics: Anesthesia, Inhalation; Animals; Halothane; Malignant Hyperthermia; Muscle Contraction; Muscles; Phy | 1976 |
Porcine malignant hyperthermia: effects of temperature and extracellular calcium concentration on halothane-induced contracture of susceptible skeletal muscle.
Topics: Animals; Caffeine; Calcium; Dose-Response Relationship, Drug; Halothane; In Vitro Techniques; Malign | 1975 |
Interaction between halothane and propranolol on oxytocin-induced uterine contractions.
Topics: Anesthetics; Animals; Calcium; Drug Interactions; Female; Halothane; In Vitro Techniques; Muscle Con | 1975 |
Halothane and isometric contractions of isolated pregnant rat myometrium.
Topics: Anesthesia, Obstetrical; Animals; Calcium; Dose-Response Relationship, Drug; Female; Halothane; In V | 1975 |
Potentiation of suxamethonium blockade by neostigmine in patients with atypical cholinesterase.
Topics: Anesthesia, Inhalation; Atropine; Child; Cholinesterases; Drug Synergism; Electric Stimulation; Halo | 1975 |
Influence of induced hypermagnesemia and hypocalcemia on neuromuscular blocking property of oxytetracycline in the horse.
Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Calcium; Female; Halothane; Heart Arrest; Horse Dis | 1975 |
An evaluation of procaine in the treatment of malignant hyperpyrexia.
Topics: Anesthesia, General; Animals; Caffeine; Contracture; Dose-Response Relationship, Drug; Drug Evaluati | 1975 |
Evaluation of creatinine phosphokinase in screening patients for malignant hyperpyrexia.
Topics: Creatine Kinase; Evaluation Studies as Topic; Halothane; Humans; In Vitro Techniques; Malignant Hype | 1975 |
[Modifications in the contractibility of the isolated rat aorta induced by halothane and enflurane].
Topics: Animals; Aorta; Enflurane; Halothane; Methyl Ethers; Muscle Contraction; Rats | 1975 |
Porcine malignant hyperthermia: effect of dantrolene sodium on in-vitro halothane-induced contraction of susceptible muscle.
Topics: Animals; Caffeine; Calcium; Contracture; Dantrolene; Halothane; Hydantoins; In Vitro Techniques; Mal | 1976 |
Halothane effects on human malignant hyperthermia skeletal muscle single calcium-release channels in planar lipid bilayers.
Topics: Calcium Channels; Disease Susceptibility; Electric Stimulation; Halothane; Humans; Lipid Bilayers; M | 1992 |
Direct inhibitory mechanisms of halothane on canine tracheal smooth muscle contraction.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Dogs; Halothane; Muscle Contraction; Muscle, Smooth; Protei | 1992 |
Modulation of Ca2+ release and Na+ channel function in skeletal muscle by fatty acids.
Topics: Calcium; Cells, Cultured; Halothane; Humans; Isoproterenol; Linolenic Acids; Malignant Hyperthermia; | 1992 |
W-7, a calmodulin antagonist, and contracture of malignant hyperthermia susceptible skeletal muscle.
Topics: Animals; Caffeine; Calcium; Calmodulin; Dantrolene; Drug Synergism; Halothane; Intercellular Signali | 1992 |
Effect of Bay K 8644 on the magnitude of isoflurane and halothane contracture of skeletal muscle from patients susceptible to malignant hyperthermia.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
Halothane relaxes preconstricted small and medium isolated porcine coronary artery segments more than isoflurane.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
Na(+)-Ca2+ exchange influences halothane and caffeine contractures of malignant hyperthermic skeletal muscle.
Topics: Animals; Caffeine; Calcium; Carrier Proteins; Culture Media; Halothane; Kinetics; Malignant Hyperthe | 1992 |
Evaluation of greyhound susceptibility to malignant hyperthermia using halothane-succinylcholine anesthesia and caffeine-halothane muscle contractures.
Topics: Anesthesia, Inhalation; Animals; Caffeine; Disease Susceptibility; Dog Diseases; Dogs; Genetic Predi | 1992 |
Is the "K-type" caffeine-halothane responder susceptible to malignant hyperthermia?
Topics: Caffeine; Culture Techniques; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Mus | 1992 |
Propofol anaesthesia in malignant hyperpyrexia susceptible swine.
Topics: Anesthesia; Animals; Caffeine; Female; Halothane; Injections, Intravenous; Male; Malignant Hyperther | 1992 |
Effect of halothane equilibration kinetics on in vitro muscle contractures for malignant hyperthermia screening.
Topics: Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contr | 1992 |
Propofol is a 'safe' anaesthetic agent in malignant hyperthermia susceptible patients.
Topics: Adolescent; Adult; Anesthesia, Intravenous; Caffeine; Contracture; Disease Susceptibility; Halothane | 1992 |
Halothane does not depress contractile function of fresh or fatigued diaphragm in pentobarbitone-anaesthetized dogs.
Topics: Anesthesia, Intravenous; Animals; Blood Pressure; Depression, Chemical; Diaphragm; Dogs; Halothane; | 1992 |
Cerebral vascular responses to anesthetics.
Topics: Anesthetics; Animals; Arginine; Calcium Channels; Cerebral Arteries; Cerebrovascular Circulation; Do | 1991 |
Interactions of volatile anesthetics and reactive oxygen intermediates on vascular smooth muscle.
Topics: Anesthetics; Animals; Calcium; Calcium Channels; Cell Membrane; Dogs; Free Radicals; Halothane; In V | 1991 |
Effects of neuroleptic agents on rat skeletal muscle contracture in vitro.
Topics: Animals; Antipsychotic Agents; Diaphragm; Droperidol; Drug Synergism; Haloperidol; Halothane; In Vit | 1991 |
Evidence for related myopathies in exertional heat stroke and malignant hyperthermia.
Topics: Adult; Biopsy; Caffeine; Disease Susceptibility; Family Health; Female; Halothane; Heat Exhaustion; | 1991 |
Use of the calcium agonist BAY K 8644 for in vitro diagnosis of susceptibility to malignant hyperthermia.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Effects of calcium-free solution, calcium antagonists, and the calcium agonist BAY K 8644 on mechanical responses of skeletal muscle from patients susceptible to malignant hyperthermia.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
BAY K 8644 and nifedipine alter halothane but not caffeine contractures of malignant hyperthermic muscle fibers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
Effects of BAY K 8644, nifedipine, and low Ca2+ on halothane and caffeine potentiation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
Is resting membrane potential a possible indicator of viability of muscle bundles used in the in vitro caffeine contracture test?
Topics: Caffeine; Electric Stimulation; Halothane; Humans; Malignant Hyperthermia; Membrane Potentials; Musc | 1992 |
Halothane- and enflurane-induced inhibition of phasic responses to carbachol in isolated guinea pig trachea.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Enflurane; Guinea Pigs; Halothane; Kinetics; M | 1992 |
In vitro contracture tests in patients with various neuromuscular diseases.
Topics: Adolescent; Adult; Aged; Caffeine; Child; Child, Preschool; Disease Susceptibility; Drug Hypersensit | 1992 |
Effects of ketamine, thiopental sodium and propofol on muscle contractures in rat diaphragm in vitro.
Topics: Animals; Caffeine; Diaphragm; Drug Synergism; Female; Halothane; In Vitro Techniques; Ketamine; Male | 1991 |
Why does halothane relax cardiac muscle but contract malignant hyperthermic skeletal muscle?
Topics: Animals; Caffeine; Calcium; Depression, Chemical; Fura-2; Halothane; In Vitro Techniques; Male; Mali | 1991 |
[Effects of volatile anesthetics on crossbridge mechanism of skeletal muscle--effects on the crossbridge in contraction].
Topics: Animals; Enflurane; Halothane; In Vitro Techniques; Muscle Contraction; Muscles; Ranidae; Rats | 1991 |
[A new emphasis on the diagnosis of malignant hyperthermia using the in vitro contracture test?].
Topics: Adolescent; Adult; Caffeine; Child; Child, Preschool; Disease Susceptibility; Halothane; Humans; In | 1991 |
[Diagnosis of malignant hyperthermia. The platelet test versus the in vitro contracture test].
Topics: Blood Platelets; Caffeine; Child; Disease Susceptibility; Halothane; Humans; Male; Malignant Hyperth | 1991 |
[In vitro diagnosis of malignant hyperpyrexia syndrome].
Topics: Adult; Caffeine; Dantrolene; Female; Halothane; Hernia, Inguinal; Humans; In Vitro Techniques; Male; | 1991 |
In vitro contraction test for malignant hyperthermia in patients with unexplained recurrent rhabdomyolysis.
Topics: Adult; Caffeine; Calcium; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hyperth | 1991 |
The effect of azumolene on hypercontractility and sarcoplasmic reticulum Ca(2+)-dependent ATPase activity of malignant hyperpyrexia-susceptible porcine skeletal muscle.
Topics: Animals; Caffeine; Calcium-Transporting ATPases; Dantrolene; Halothane; Imidazoles; Malignant Hypert | 1991 |
In vitro contracture testing for determination of susceptibility to malignant hyperthermia: a methodologic update.
Topics: Caffeine; Chromatography, Gas; Contracture; Diffusion Chambers, Culture; Disease Susceptibility; Ele | 1991 |
Ca release from skeletal muscle SR. Effects of volatile anesthetics.
Topics: Anesthetics; Animals; Calcium; Calcium-Transporting ATPases; Calmodulin; Halothane; In Vitro Techniq | 1991 |
Pharmacogenetics of caffeine and caffeine-halothane contractures in biopsies of human skeletal muscle.
Topics: Adolescent; Adult; Aged; Aging; Caffeine; Child; Child, Preschool; Female; Genetic Variation; Haloth | 1991 |
Attenuation of contraction of isolated canine coronary arteries by enflurane and halothane.
Topics: Animals; Calcium; Calcium Channels; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Enflur | 1991 |
Characterization of swine susceptible to malignant hyperthermia by in vivo, in vitro and post-mortem techniques.
Topics: Administration, Inhalation; Animals; Caffeine; Creatine Kinase; Disease Susceptibility; Genotype; Ha | 1991 |
Malignant hyperthermia: normal muscle calcium uptake and abnormal caffeine and halothane contractures.
Topics: Adult; Biopsy; Caffeine; Calcium; Disease Susceptibility; False Negative Reactions; Female; Halothan | 1991 |
Comparison of North American and European malignant hyperthermia group halothane contracture testing protocols in swine.
Topics: Animals; Disease Susceptibility; Europe; Halothane; Malignant Hyperthermia; Muscle Contraction; Nort | 1991 |
Ryanodine receptor gene is a candidate for predisposition to malignant hyperthermia.
Topics: Animals; Caffeine; Chromosomes, Human, Pair 19; Female; Genetic Linkage; Halothane; Heterozygote; Ho | 1990 |
The effects of halothane, enflurane, and isoflurane on the length-tension relation of the isolated ventricular papillary muscle of the ferret.
Topics: Animals; Depression, Chemical; Enflurane; Ferrets; Halothane; In Vitro Techniques; Isoflurane; Male; | 1991 |
Halothane 1.5 MAC, isoflurane 1.5 MAC, and the contractile responses of coronary arteries obtained from human hearts.
Topics: Adult; Coronary Vessels; Dinoprost; Female; Halothane; Histamine; Humans; In Vitro Techniques; Isofl | 1991 |
Malignant hyperthermia in dogs.
Topics: Animals; Biopsy; Caffeine; Crosses, Genetic; Dantrolene; Dog Diseases; Dogs; Female; Halothane; Hear | 1991 |
[Diagnosis of susceptibility for malignant hyperthermia using in-vitro muscle contraction testing in Switzerland].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biopsy; Caffeine; Child; Female; Genetic Predisposition | 1991 |
A comparison of the caffeine halothane muscle contracture test with the molecular genetic diagnosis of malignant hyperthermia.
Topics: Alleles; Caffeine; Child; Female; Genetic Linkage; Genetic Markers; Halothane; Humans; Male; Maligna | 1991 |
Halothane-dependent release of intracellular Ca2+ in blood cells in malignant hyperthermia.
Topics: Animals; Caffeine; Calcium; Cytosol; Disease Susceptibility; Egtazic Acid; Halothane; Humans; Malign | 1990 |
Comparison of the direct effects of halothane and isoflurane on large and small coronary arteries isolated from dogs.
Topics: Adenosine; Animals; Coronary Vessels; Dogs; Female; Halothane; In Vitro Techniques; Isoflurane; Male | 1990 |
Fatty acids modulate calcium-induced calcium release from skeletal muscle heavy sarcoplasmic reticulum fractions: implications for malignant hyperthermia.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Chromatography, Gas; Fatty Acids; Halothane; | 1990 |
Influence of halothane on the train-of-four fade after atracurium in children.
Topics: Anesthesia, General; Atracurium; Child; Child, Preschool; Halothane; Humans; Muscle Contraction; Neu | 1990 |
The importance of calcium ions for in vitro malignant hyperthermia testing.
Topics: Caffeine; Calcium; Contracture; Drug Interactions; Halothane; Humans; In Vitro Techniques; Malignant | 1990 |
Halothane cooling contractures of skinned mammalian muscle fibers.
Topics: Action Potentials; Animals; Caffeine; Calcium; Cold Temperature; Halothane; In Vitro Techniques; Lid | 1990 |
Are myotonias and periodic paralyses associated with susceptibility to malignant hyperthermia?
Topics: Biopsy; Caffeine; Calcium; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant | 1990 |
Potentiation of the halothane-cooling contractures of mammalian muscles by denervation.
Topics: Animals; Calcium; Cold Temperature; Halothane; Mice; Muscle Contraction; Muscle Denervation; Muscles | 1990 |
Caffeine and halothane contracture testing in swine using the recommendations of the North American Malignant Hyperthermia Group.
Topics: Animals; Caffeine; Disease Susceptibility; Halothane; In Vitro Techniques; Malignant Hyperthermia; M | 1990 |
Localization of the malignant hyperthermia susceptibility locus to human chromosome 19q12-13.2.
Topics: Animals; Caffeine; Chromosome Mapping; Chromosomes, Human, Pair 19; Female; Genetic Linkage; Halotha | 1990 |
Clinical concentrations of verapamil affect the in vitro diagnosis of susceptibility to malignant hyperpyrexia.
Topics: Caffeine; Disease Susceptibility; False Negative Reactions; Halothane; Humans; In Vitro Techniques; | 1990 |
Different effects of halothane and enflurane on diaphragmatic contractility in vivo.
Topics: Animals; Blood Pressure; Diaphragm; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; En | 1990 |
Synergistic interaction of morphine and halothane in the guinea pig ileum: effects of pertussis toxin.
Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Guinea Pigs; Haloth | 1990 |
Direct and neurally mediated effects of halothane on pulmonary resistance in vivo.
Topics: Acetylcholine; Aerosols; Airway Resistance; Animals; Dogs; Electric Stimulation; Halothane; Muscle C | 1990 |
Current diagnostic methods of malignant hyperthermia: an evaluation.
Topics: Caffeine; Chromosomes, Human, Pair 19; Disease Susceptibility; Halothane; Humans; Magnetic Resonance | 1990 |
Diltiazem and nifedipine reduce the in vitro contracture response to halothane in malignant hyperthermia-susceptible muscle.
Topics: Depression, Chemical; Diltiazem; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Mal | 1990 |
Halothane sensitivity of young pigs in vivo and in vitro.
Topics: Animals; Drug Hypersensitivity; Halothane; Malignant Hyperthermia; Muscle Contraction; Muscles; Succ | 1990 |
Effects of the calcium antagonist, TMB-8 on halothane and on caffeine contractures of malignant hyperthermia susceptible skeletal muscle.
Topics: Animals; Caffeine; Calcium Channel Blockers; Gallic Acid; Halothane; In Vitro Techniques; Malignant | 1990 |
Compensatory increase in calcium extrusion activity of untreated lymphocytes from swine susceptible to malignant hyperthermia.
Topics: Animals; Caffeine; Calcium; Disease Susceptibility; Halothane; Lymphocytes; Malignant Hyperthermia; | 1990 |
Porcine malignant hyperthermia: critical temperatures for in vivo and in vitro responses.
Topics: Animals; Body Temperature; Calcium; Disease Susceptibility; Halothane; In Vitro Techniques; Malignan | 1990 |
The effect of halothane on norepinephrine responsiveness in rabbit small mesenteric veins.
Topics: Animals; Calcium; Halothane; In Vitro Techniques; Mesenteric Veins; Muscle Contraction; Muscle, Smoo | 1990 |
Alterations in the functional properties of skinned fibers from denervated rabbit skeletal muscle.
Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Halothane; In Vitro Techniques; Muscle Contracti | 1990 |
No relationship between fiber type and halothane contracture test results in malignant hyperthermia.
Topics: Adenosine Triphosphatases; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Muscles; S | 1987 |
[Effects of BAY K 8644, a slow calcium channel agonist, on muscle contraction induced by halothane in sensitive subjects with malignant hyperthermia].
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
Malignant hyperthermia: slow sodium current in cultured human muscle cells.
Topics: Caffeine; Cells, Cultured; Disease Susceptibility; Electric Conductivity; Halothane; Humans; Maligna | 1989 |
Inositol 1,4,5-trisphosphate phosphatase deficiency and malignant hyperpyrexia in swine.
Topics: Animals; Calcium; Halothane; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Malignant Hypertherm | 1989 |
The association between the neuroleptic malignant syndrome and malignant hyperthermia.
Topics: Adult; Caffeine; Chlorpromazine; Contracture; Disease Susceptibility; Female; Halothane; Humans; Mal | 1989 |
Effects of atracurium administered by continuous intravenous infusion in halothane-anesthetized horses.
Topics: Anesthesia Recovery Period; Animals; Atracurium; Female; Halothane; Hindlimb; Hoof and Claw; Horses; | 1989 |
Effect of diltiazem, verapamil and dantrolene on the contractility of isolated malignant hyperpyrexia-susceptible human skeletal muscle.
Topics: Caffeine; Dantrolene; Diltiazem; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Mal | 1989 |
[The action of ketamine on muscle contractile behavior. In vitro studies on the musculature of subjects susceptible to malignant hyperthermia].
Topics: Caffeine; Disease Susceptibility; Halothane; In Vitro Techniques; Ketamine; Malignant Hyperthermia; | 1989 |
[Malignant hyperthermia; two cases of MH in the presence of general anesthesia and performing caffeine contracture test].
Topics: Adult; Caffeine; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscle Contra | 1989 |
Malignant hyperthermia: effects of halothane on the surface membrane.
Topics: Action Potentials; Animals; Dantrolene; Halothane; Malignant Hyperthermia; Membrane Potentials; Musc | 1989 |
The in vitro determination of susceptibility to malignant hyperthermia.
Topics: Animals; Caffeine; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Swine | 1989 |
Influence of halothane on contraction at positive membrane potentials in single cells isolated from guinea-pig ventricular muscle.
Topics: Animals; Guinea Pigs; Halothane; In Vitro Techniques; Isoflurane; Membrane Potentials; Muscle Contra | 1989 |
Effect of diltiazem and dantrolene on the contractility of isolated malignant hyperpyrexia-susceptible porcine skeletal muscle.
Topics: Animals; Caffeine; Dantrolene; Diltiazem; Dose-Response Relationship, Drug; Halothane; In Vitro Tech | 1989 |
Porcine malignant hyperthermia: halothane effects on force generation in skeletal muscles.
Topics: Animals; Calcium; Electric Stimulation; Halothane; Malignant Hyperthermia; Muscle Contraction; Muscl | 1989 |
Intracellular mechanisms of halothane's effect on isolated aortic strips of the rabbit.
Topics: Acetylcholine; Animals; Aorta; Caffeine; Calcium; Endothelium, Vascular; Halothane; In Vitro Techniq | 1989 |
Standards for halothane/caffeine contracture test.
Topics: Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction | 1989 |
Malignant hyperthermia in humans--standardization of contracture testing protocol.
Topics: Biopsy; Caffeine; Clinical Laboratory Techniques; Drug Combinations; Halothane; Humans; Malignant Hy | 1989 |
Fluoxetine treatment of a depressed patient susceptible to malignant hyperthermia.
Topics: Adolescent; Caffeine; Depressive Disorder; Disease Susceptibility; Female; Fluoxetine; Halothane; Hu | 1989 |
Halothane-sensitivity gene and muscle contractile properties in malignant hyperthermia.
Topics: Animals; Genes; Genetic Carrier Screening; Halothane; Homozygote; Malignant Hyperthermia; Muscle Con | 1989 |
Failure of lower esophageal contractility to predict patient movement in children anesthetized with halothane and nitrous oxide.
Topics: Adolescent; Anesthesia, General; Child; Dermatologic Surgical Procedures; Esophagus; Forecasting; Ha | 1989 |
[Diagnosis of susceptibility to malignant hyperthermia using the in vitro contracture test].
Topics: Adolescent; Adult; Aged; Anesthesia; Electromyography; Female; Halothane; Humans; In Vitro Technique | 1987 |
Clinical pharmacology of vecuronium in children. Studies during nitrous oxide and halothane in oxygen anaesthesia.
Topics: Anesthesia, Inhalation; Child; Child, Preschool; Dose-Response Relationship, Drug; Halothane; Hemody | 1986 |
Anaesthetic-induced increase in ionised calcium in blood mononuclear cells from malignant hyperthermia patients.
Topics: Aminoquinolines; Anesthetics; Caffeine; Calcium; Drug Evaluation; Halothane; Humans; In Vitro Techni | 1987 |
Evaluation of intense neuromuscular blockade caused by vecuronium using posttetanic count (PTC).
Topics: Anesthesia, Inhalation; Fentanyl; Halothane; Humans; Muscle Contraction; Neuromuscular Junction; Vec | 1987 |
[Antagonism of an intubation dose of vecuronium].
Topics: Anesthesia; Edrophonium; Halothane; Humans; Intubation; Muscle Contraction; Muscle Relaxation; Neost | 1987 |
The onset of ablation of the evoked adductor pollicis muscle twitch in children: a clinical perspective.
Topics: Adolescent; Anesthesia, Inhalation; Child; Child, Preschool; Depression, Chemical; Electric Stimulat | 1988 |
The effect of anesthetics on lymphatic contractility.
Topics: Anesthetics; Animals; Cattle; Electric Stimulation; Ether; Halothane; In Vitro Techniques; Lymphatic | 1989 |
The effect of halothane, enflurane, and isoflurane on the dynamic stiffness of rabbit papillary muscle.
Topics: Animals; Barium; Dose-Response Relationship, Drug; Enflurane; Halothane; Isoflurane; Muscle Contract | 1989 |
Prolonged hyporesponsiveness of vascular smooth muscle contraction after halothane anesthesia in rabbits.
Topics: Anesthesia; Animals; Aorta; Halothane; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth | 1985 |
Effects of halothane on the mechanical responses in vitro of coronary arterial rings of malignant hyperthermia susceptible swine.
Topics: Animals; Coronary Vessels; Epinephrine; Halothane; In Vitro Techniques; Malignant Hyperthermia; Musc | 1988 |
Effect of fiber types, fascicle size and halothane on caffeine contractures in rat muscles.
Topics: Animals; Caffeine; Halothane; In Vitro Techniques; Muscle Contraction; Muscles; Rats; Rats, Inbred S | 1988 |
Calmodulin-antagonist drugs and porcine malignant hyperpyrexia.
Topics: Animals; Caffeine; Calmodulin; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contra | 1988 |
Age, fiber type composition and in vitro contracture responses in human malignant hyperthermia.
Topics: Adolescent; Adult; Aging; Caffeine; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; | 1988 |
Synergistic interaction of morphine and halothane in the guinea pig ileum.
Topics: Animals; Drug Synergism; Guinea Pigs; Halothane; Ileum; In Vitro Techniques; Morphine; Muscle Contra | 1988 |
Halothane-caffeine contracture testing in neuromuscular diseases.
Topics: Biopsy; Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Muscles; Neuromuscu | 1988 |
Fura-2 detected myoplasmic calcium and its correlation with contracture force in skeletal muscle from normal and malignant hyperthermia susceptible pigs.
Topics: Animals; Benzofurans; Caffeine; Calcium; Disease Susceptibility; Fura-2; Halothane; Malignant Hypert | 1988 |
[Malignant hyperthermia in Austria. II. A comparison of the results of diagnostic test procedures].
Topics: Adult; Caffeine; Creatine Kinase; Disease Susceptibility; Electromyography; Female; Halothane; Human | 1988 |
Neuromuscular and cardiovascular effects of atracurium administered to healthy horses anesthetized with halothane.
Topics: Anesthesia, Inhalation; Animals; Atracurium; Blood Pressure; Edrophonium; Halothane; Heart Rate; Hor | 1988 |
Neuroleptic malignant syndrome and malignant hyperthermia. In vitro comparison with halothane and caffeine contracture tests.
Topics: Adult; Aged; Caffeine; Disease Susceptibility; Female; Halothane; Humans; In Vitro Techniques; Male; | 1987 |
Prediction of malignant hyperthermia susceptibility by clinical signs.
Topics: Adolescent; Anesthesia, General; Biopsy; Caffeine; Child; Halothane; Humans; Infant; Malignant Hyper | 1987 |
Porcine malignant hyperthermia: false negatives in the halothane test.
Topics: Animals; Disease Susceptibility; False Negative Reactions; Genotype; Halothane; Malignant Hypertherm | 1987 |
Abnormal relaxation rates in subjects susceptible to malignant hyperthermia.
Topics: Adolescent; Adult; Caffeine; Electromyography; Female; Halothane; Humans; Male; Malignant Hypertherm | 1987 |
In vitro diagnosis of susceptibility to malignant hyperthermia: evaluation of tests with halothane-caffeine, potassium chloride, suxamethonium and caffeine-suxamethonium.
Topics: Caffeine; Disease Susceptibility; Evaluation Studies as Topic; Halothane; Humans; In Vitro Technique | 1987 |
In vitro diagnosis of susceptibility to malignant hyperthermia: comparison between dynamic and static halothane and caffeine tests.
Topics: Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Mu | 1987 |
Relationship between lower oesophageal contractility, clinical signs and halothane concentration during general anaesthesia and surgery in man.
Topics: Adult; Anesthesia, General; Esophagus; Female; Halothane; Humans; Male; Middle Aged; Muscle Contract | 1987 |
Different effects of halothane on diaphragm and hindlimb muscle in rats.
Topics: Animals; Diaphragm; Halothane; Hindlimb; Muscle Contraction; Muscles; Rats | 1987 |
Halothane-cooling contractures of mammalian muscles.
Topics: Anesthetics, Local; Animals; Caffeine; Calcium; Cold Temperature; Dantrolene; Dose-Response Relation | 1986 |
Static v. dynamic tests in the in vitro diagnosis of malignant hyperthermia susceptibility.
Topics: Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Male; Malignant Hypertherm | 1986 |
[Contracture response to isoflurane and pentazocine in muscles of a patient with malignant hyperthermia].
Topics: Caffeine; Child; Halothane; Humans; In Vitro Techniques; Isoflurane; Male; Malignant Hyperthermia; M | 1986 |
Prolonged hyporesponsiveness of airway smooth muscle to histamine following general anesthesia.
Topics: Anesthesia, General; Animals; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Halothan | 1986 |
Action of halothane on rat soleus muscle: temperature dependent induction of contractures and modification of caffeine and potassium contractures.
Topics: Animals; Caffeine; Calcium; Dose-Response Relationship, Drug; Drug Synergism; Female; Halothane; In | 1986 |
Does halothane really reduce diaphragmatic contractility?
Topics: Animals; Diaphragm; Halothane; Humans; Muscle Contraction; Pressure | 1986 |
In vitro muscle contractures induced by halothane and suxamethonium. I: The rat diaphragm.
Topics: Animals; Dantrolene; Diaphragm; Drug Synergism; Halothane; In Vitro Techniques; Indomethacin; Male; | 1986 |
In vitro muscle contractures induced by halothane and suxamethonium. II: Human skeletal muscle from normal and malignant hyperthermia susceptible patients.
Topics: Disease Susceptibility; Fatty Acids, Nonesterified; Halothane; Humans; In Vitro Techniques; Indometh | 1986 |
Effects of halothane, enflurane, and nitrous oxide on colon motility.
Topics: Animals; Colon; Electrophysiology; Enflurane; Gastrointestinal Motility; Halothane; Macaca; Muscle C | 1987 |
Intraocular pressure changes during muscular hyperactivity after general anesthesia.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Halothane; Humans; Hyperkinesis; Intraocular | 1987 |
[Detection of peranesthetic malignant hyperthermia by muscle contracture tests and NMR spectroscopy].
Topics: Biopsy; Caffeine; Halothane; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Malignant | 1986 |
Diagnosis of malignant hyperthermia: implications for the military.
Topics: Adolescent; Adult; Caffeine; Halothane; Humans; Male; Malignant Hyperthermia; Military Medicine; Mus | 1985 |
Malignant hyperthermia.
Topics: Adult; Anesthesia; Animals; Caffeine; Child; Creatine Kinase; Disease Susceptibility; Halothane; Hum | 1985 |
Masseter muscle rigidity and malignant hyperthermia susceptibility.
Topics: Caffeine; Child; Creatine Kinase; Female; Halothane; Humans; Male; Malignant Hyperthermia; Masseter | 1986 |
Failure of the platelet-halothane nucleotide depletion test as a diagnostic or screening test for malignant hyperthermia.
Topics: Blood Platelets; Caffeine; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Co | 1986 |
Effect of halothane on diaphragmatic muscle function in pentobarbital-anesthetized dogs.
Topics: Anesthesia; Animals; Diaphragm; Dogs; Dose-Response Relationship, Drug; Electromyography; Halothane; | 1986 |
The temperature dependence of halothane-induced contractures of skeletal muscle.
Topics: Anesthetics, Local; Animals; Anura; Caffeine; Calcium; Disease Models, Animal; Halothane; In Vitro T | 1986 |
Porcine malignant hyperthermia: cell injury enhances halothane sensitivity of biopsies.
Topics: Animals; Caffeine; Disease Susceptibility; Halothane; Hybridization, Genetic; In Vitro Techniques; M | 1986 |
Verapamil and zero Ca2+ alter responses of cat muscle to halothane and caffeine.
Topics: Animals; Caffeine; Calcium; Cats; Dose-Response Relationship, Drug; Drug Synergism; Extracellular Sp | 1986 |
Intracellular mechanism of action of isoflurane and halothane on striated muscle of the rabbit.
Topics: Animals; Caffeine; Calcium; Drug Interactions; Halothane; In Vitro Techniques; Isoflurane; Methyl Et | 1986 |
Electrophoresis of muscle proteins is not a method for diagnosis of malignant hyperthermia susceptibility.
Topics: Caffeine; Electrophoresis, Polyacrylamide Gel; Halothane; Humans; Malignant Hyperthermia; Molecular | 1986 |
In vitro responses of cat skeletal muscle to halothane and caffeine.
Topics: Animals; Caffeine; Cats; Dantrolene; Dose-Response Relationship, Drug; Electric Stimulation; Halotha | 1985 |
Malignant hyperthermia: is etomidate safe?
Topics: Animals; Blood Gas Analysis; Body Temperature; Etomidate; Fentanyl; Halothane; Heart Rate; Imidazole | 1985 |
Verapamil is not a therapeutic adjunct to dantrolene in porcine malignant hyperthermia.
Topics: Anesthesia, Inhalation; Animals; Blood Gas Analysis; Blood Pressure; Dantrolene; Drug Synergism; Hal | 1985 |
Myoadenylate deaminase deficiency: inherited and acquired forms.
Topics: Adenylate Kinase; Ammonia; AMP Deaminase; Biopsy; Caffeine; Creatine Kinase; Female; Genetic Carrier | 1985 |
In vitro interaction between halothane and succinylcholine in human skeletal muscle: implications for malignant hyperthermia and masseter muscle rigidity.
Topics: Caffeine; Disease Susceptibility; Drug Interactions; Halothane; Humans; In Vitro Techniques; Maligna | 1985 |
Diltiazem inhibits halothane-induced contractions in malignant hyperthermia-susceptible muscles in vitro.
Topics: Animals; Benzazepines; Caffeine; Depression, Chemical; Diltiazem; Disease Susceptibility; Halothane; | 1985 |
Unusual response following use of succinylcholine in a horse anesthetized with halothane.
Topics: Anesthesia, General; Animals; Female; Halothane; Horse Diseases; Horses; Malignant Hyperthermia; Mus | 1985 |
[Determination of intracellular free calcium concentration, in vivo, in swine susceptible to malignant hyperthermia syndrome].
Topics: Animals; Calcium; Dantrolene; Halothane; Malignant Hyperthermia; Membrane Potentials; Muscle Contrac | 1985 |
Myoadenylate deaminase deficiency and malignant hyperthermia susceptibility: is there a relationship?
Topics: Adenylate Kinase; Adult; AMP Deaminase; Caffeine; Creatine Kinase; Disease Susceptibility; Female; H | 1985 |
Metabolic error of muscle metabolism after recovery from malignant hyperthermia.
Topics: Adolescent; Adult; Anesthesia, General; Caffeine; Calcium; Contracture; Female; Fever; Halothane; Hu | 1970 |
Effects of halothane on the cyclic 3',5'-adenosine monophosphate (cyclic AMP) system in rat uterine muscle.
Topics: Acetylcholine; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Chromatography, Gas; Culture | 1973 |
[Comparative studies on the effect of Veratrum alkaloids on cardiac contraction kinetics].
Topics: Acetylcholine; Biomechanical Phenomena; Bradycardia; Chloroform; Chlorpromazine; Depression, Chemica | 1967 |
The effect of fructose on halothane-depressed rat atria.
Topics: Animals; Bicarbonates; Fructose; Glucose; Halothane; Heart Atria; Lactates; Male; Muscle Contraction | 1970 |
Effects of anaesthetics and their interactions with neuromuscular blocking agents in cats.
Topics: Animals; Blood Pressure; Cats; Chloralose; Drug Synergism; Electric Stimulation; Gallamine Triethiod | 1970 |
Malignant hyperthermia--an investigation of three patients.
Topics: Adenosine Triphosphatases; Anesthesia, General; Aspartate Aminotransferases; Body Temperature; Caffe | 1971 |
Rate of depression of atrial contractility inducted by citrate, bicarbonate-free medium, hydrochloric acid, and halothane.
Topics: Animals; Anti-Arrhythmia Agents; Bicarbonates; Citrates; Culture Media; Depression, Chemical; Glucos | 1971 |
Some effects of the steroidal muscle relaxant, dacuronium bromide, in anaesthetized patients.
Topics: Androstanes; Anesthesia, General; Blood Pressure; Electrophysiology; Halothane; Heart Rate; Humans; | 1971 |
Relationship between pulmonary ventilation and serial changes in tetanus fading, with special reference to cumulative effects of pancuronium.
Topics: Adult; Aged; Androstanes; Anesthesia, Epidural; Electric Stimulation; Electrophysiology; Halothane; | 1971 |
[Effect of propanidid, methohexital and halothane on the isometric contraction of the isolated heart muscle].
Topics: Anesthetics; Animals; Depression, Chemical; Guinea Pigs; Halothane; Methohexital; Muscle Contraction | 1971 |
Effect of halothane on altered contractility of isolated heart muscle obtained from cats with experimentally produced ventricular hypertrophy and failure.
Topics: Animals; Blood Pressure; Cardiomegaly; Cats; Electric Stimulation; Epinephrine; Halothane; Heart Fai | 1973 |
The electromechanical response to stimulation by the Block-Aid Monitor.
Topics: Anesthesia; Atropine; Electric Stimulation; Evoked Potentials; Halothane; Humans; Methods; Muscle Co | 1969 |
The effect of magnesium sulfate on anoxia and resuscitation in the neonate.
Topics: Adrenal Medulla; Animals; Animals, Newborn; Asphyxia Neonatorum; Eclampsia; Female; Halothane; Heart | 1971 |
Neuromuscular effects of halothane, suxamethonium and tubocurarine in a myasthenic undergoing thymectomy.
Topics: Adult; Biopsy; Electromyography; Female; Halothane; Humans; Muscle Contraction; Muscles; Myasthenia | 1971 |
Procaine, pentobarbital and halothane: effects on the mammalian myoneural junction.
Topics: Animals; Axons; Diaphragm; Electric Stimulation; Evoked Potentials; Female; Halothane; In Vitro Tech | 1971 |
The effect of halothane on the neuromuscular blocking action of pancuronium (Pavulon).
Topics: Androstanes; Anesthesia, General; Drug Synergism; Electric Stimulation; Electromyography; Female; Ha | 1972 |
Effect of anesthetics on acetylcholine release from the myoneural junction.
Topics: Acetylcholine; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Animals; Anura; Ethyl E | 1972 |
The electromyogram and the mechanical response of indirectly stimulated muscle in anesthetized man following curarization.
Topics: Action Potentials; Administration, Oral; Anesthesia, Inhalation; Depression, Chemical; Electric Stim | 1973 |
Effects of isoflurane and halothane on contractility and the cyclic 3', 5'-adenosine monophosphate system in the rat aorta.
Topics: Anesthetics; Animals; Aorta; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Ethers; H | 1974 |
Repetitive muscle depolarization from single indirect stimulation in anesthetized man.
Topics: Anesthetics; Cyclopropanes; Electric Stimulation; Electromyography; Ethers; Ethyl Ethers; Halothane; | 1970 |
Electroencephalographic seizure activity in dogs during anaesthesia.
Topics: Anesthetics; Animals; Carbon Dioxide; Chloroform; Cyclopropanes; Dogs; Electroencephalography; Ether | 1971 |
The reversal of experimental cardiac arrhythmias by indoramin (Wy 21901).
Topics: Amides; Anesthetics, Local; Animals; Arrhythmia, Sinus; Arrhythmias, Cardiac; Blood Pressure; Cats; | 1971 |
[Compared action of halothane, methoxyflurane and enflurane].
Topics: Blood Pressure; Chlorine; Ethers; Fluorine; Halothane; Heart Rate; Humans; Intraocular Pressure; Met | 1974 |
The potentiation of the neuromuscular blocking activity of hexafluorenium and d-tubocurarine by volatile anaesthetics.
Topics: Anesthetics; Animals; Cats; Drug Synergism; Ethers; Female; Fluorenes; Halothane; Male; Muscle Contr | 1974 |
[Muscle relaxation through relaxants, hyperventilation and narcotics].
Topics: Anesthetics; Carbon Dioxide; Diaphragm; Drug Synergism; Halothane; Humans; Hyperventilation; Male; M | 1974 |
Effect of anaesthetic agents on broncho-motor tone and on histamine induced bronchospasm.
Topics: Anesthesia, Inhalation; Anesthetics; Bronchi; Bronchial Spasm; Chloroform; Ether; Halothane; Histami | 1974 |
The anaesthetist and the ophthalmic surgeon.
Topics: Anesthesia, General; Animals; Blood Pressure; Carbon Dioxide; Curare; Diazepam; Dogs; Eye Diseases; | 1973 |
The effects of halothane on the interactions between myocardial contractility, aortic impedance, and left ventricular performance. I. Theoretical considerations and results.
Topics: Anesthesia, Inhalation; Animals; Aorta; Blood Flow Velocity; Blood Pressure; Cardiac Output; Cardiac | 1972 |
Procaine in malignant hyperpyrexia.
Topics: Aged; Caffeine; Female; Halothane; Humans; In Vitro Techniques; Lidocaine; Malignant Hyperthermia; M | 1972 |
Histopathological and neuropharmacological aspects of malignant hyperpyrexia.
Topics: Adult; Anesthesia, General; Caffeine; Child; Child, Preschool; Creatine Kinase; Female; Halothane; H | 1973 |
[Negative inotropic effect of inhalation anaesthetics and the compensation of this effect by cardiac glycosides].
Topics: Animals; Arrhythmias, Cardiac; Cardiac Glycosides; Cats; Chloroform; Chromatography, Gas; Drug Antag | 1973 |
Mechanical measurement of neuromuscular blockade. A comparison between the force transducer and a simple muscle twitch monitor.
Topics: Electric Stimulation; Halothane; Humans; Manometry; Muscle Contraction; Neuromuscular Depolarizing A | 1973 |
Evaluation of pharmacologic agents for restraint in cystometry in the dog and cat.
Topics: Acepromazine; Air; Anesthesia; Aniline Compounds; Animals; Cats; Dogs; Droperidol; Female; Fentanyl; | 1973 |
Malignant hyperpyrexia.
Topics: Adolescent; Adult; Biopsy; Child; Child, Preschool; Creatine Kinase; Female; Halothane; Humans; Male | 1973 |
A new screening test for susceptibility to malignant hyperpyrexia.
Topics: Diagnosis, Differential; Halothane; Humans; Malignant Hyperthermia; Methods; Muscle Contraction | 1973 |
Malignant hyperthermia: an investigation of five patients.
Topics: Adolescent; Adult; Aspartate Aminotransferases; Calcium; Clinical Enzyme Tests; Creatine Kinase; Ele | 1973 |
Factors influencing the development of expiratory muscle activity during anaesthesia.
Topics: Adult; Airway Obstruction; Anesthesia, General; Anesthesia, Local; Electric Stimulation; Electrocard | 1973 |
Malignant hyperpyrexia myopathy.
Topics: Adolescent; Adult; Anesthesia, General; Atrophy; Biopsy; Child; Child, Preschool; Female; Halothane; | 1973 |
Biochemical basis of malignant hyperpyrexia.
Topics: Biopsy; Caffeine; Calcium; Cell Membrane; Creatine Kinase; Extracellular Space; Halothane; Humans; I | 1974 |
Comparative times to peak effect and durations of action of neostigmine and pyridostigmine.
Topics: Anesthesia, Inhalation; Animals; Electric Stimulation; Halothane; Humans; Muscle Contraction; Neosti | 1974 |
Comparison in vitro of isoflurane and halothane potentiation of d-tubocurarine and succinylcholine neuromuscular blockades.
Topics: Anesthetics; Animals; Diaphragm; Drug Synergism; Electric Stimulation; Ethers; Halothane; Hydrocarbo | 1974 |
The effects of decamethonium (C-10) on blood pressure and heart rate in newborn piglets.
Topics: Acetylcholine; Aging; Anesthesia; Animals; Animals, Newborn; Blood Pressure; Carbon Dioxide; Decamet | 1974 |
The correlation between haemodynamic changes and arterial blood halothane concentrations during halothane-nitrous oxide anaesthesia in the dog.
Topics: Anesthesia, Inhalation; Animals; Aorta; Blood Pressure; Cardiac Output; Cardiac Volume; Central Veno | 1971 |
The interaction between d-tubocurarine and gallamine during halothane anaesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Animals; Blood Pressure; Body Surface Area; Child; | 1972 |
The effect of suxamethonium on the intragastric pressure in infants and children.
Topics: Adjuvants, Anesthesia; Child; Child, Preschool; Halothane; Humans; Infant; Infant, Newborn; Injectio | 1972 |
Pa CO2 and the pre-ejection period: the pa CO2 inotropy response curve.
Topics: Adult; Age Factors; Aged; Anesthesia, General; Animals; Biomechanical Phenomena; Carbon Dioxide; Dog | 1972 |
Screening for malignant hyperpyrexia.
Topics: Acidosis; Adolescent; Adult; Anesthesia, General; Biopsy; Child; Child, Preschool; Creatine Kinase; | 1972 |
Antiarrhythmic effects of droperidol.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benperidol; Blood Pressure; Cats; Coronary Ve | 1972 |
Malignant hyperpyrexia.
Topics: Acidosis; Anesthesia, General; Fever; Halothane; Humans; Isoproterenol; Muscle Contraction; Procaine | 1971 |
[Experience with Ketalar anesthesia].
Topics: Anesthetics; Blood Pressure; Child; Cyclohexanes; Cyclopropanes; Female; Halothane; Humans; Hyperten | 1971 |
[Cardiovascular effect of a cardiac glycoside, proscillaridin A].
Topics: Animals; Blood Pressure; Blood Vessels; Bufanolides; Digitalis Glycosides; Dogs; Halothane; Heart; H | 1971 |
An in-vitro model of anesthetic hypertonic hyperpyrexia, halothane--caffeine-induced muscle contractures: prevention of contracture by procainamide.
Topics: Anesthesia, Inhalation; Animals; Anura; Caffeine; Culture Techniques; Drug Synergism; Fever; Halotha | 1971 |
The effects of succinylcholine and d-tubocurarine on oxygen consumption.
Topics: Anesthetics; Animals; Blood Pressure; Dogs; Halothane; Muscle Contraction; Muscles; Oxygen Consumpti | 1969 |
The effect of hexafluorenium on the neuromuscular refractory period of anesthetized man.
Topics: Action Potentials; Adult; Anesthesia; Female; Halothane; Humans; Male; Middle Aged; Muscle Contracti | 1969 |
[Effect of anesthetics on the heart and blood vessels].
Topics: Anesthetics; Anesthetics, Local; Animals; Antihypertensive Agents; Barbiturates; Blood Circulation; | 1969 |
[Clinical experiences in obstetrical anesthesia].
Topics: Anesthesia, Obstetrical; Barbiturates; Chromatography, Gas; Female; Halothane; Heart Rate; Humans; M | 1969 |
[Methoxyflurane and isolated abdominal splanchnic vessels. Comparison with halothane].
Topics: Animals; Cattle; Celiac Artery; Halothane; Membrane Potentials; Mesenteric Arteries; Methoxyflurane; | 1969 |
The relationship between depressed myocardial contractility and the stroke output of the canine heart during halothane anaesthesia.
Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Halothane; Heart Rate; Muscle Contraction; Vascular R | 1970 |
New techniques of measurement of relaxants and their antagonists.
Topics: Colon; Decamethonium Compounds; Gallamine Triethiodide; Gastrointestinal Motility; Halothane; Humans | 1970 |
Evidence for beta-receptor activation produced by halothane in normal man.
Topics: Acidosis; Adult; Anesthesia, General; Arteries; Blood Pressure; Carbon Dioxide; Cardiac Output; Halo | 1970 |
Cardiovascular effects of halothane in man.
Topics: Adult; Analysis of Variance; Anesthesia, General; Arteries; Blood Pressure; Body Temperature; Carbon | 1970 |
Effect of halothane on contractile function and reactivity of myocardium.
Topics: Animals; Cats; Electric Stimulation; Guinea Pigs; Halothane; Heart; Heart Atria; Heart Rate; Heart V | 1970 |
The effects of substrates on halothane-depressed isolated human atria.
Topics: Acetates; Child; Female; Fructose; Glucose; Halothane; Heart; Heart Atria; Humans; In Vitro Techniqu | 1970 |
The effects of halothane and cyclopropane on the maximum acceleration of left ventricular ejection and the tension-time index in dogs.
Topics: Animals; Cardiac Catheterization; Cardiac Output; Cyclopropanes; Depression, Chemical; Dogs; Elastic | 1971 |
The interaction of diazepam with myoneural blocking agents.
Topics: Acetylcholine; Adjuvants, Anesthesia; Adult; Animals; Cats; Chickens; Decamethonium Compounds; Diaze | 1971 |
The effect of halothane on the contractility of atria from starved rats.
Topics: Animals; Depression, Chemical; Elasticity; Fatty Acids; Glucose; Glucose-6-Phosphate Isomerase; Glyc | 1971 |
Diethyl ether and contractility of isolated cat heart muscle. Comparison of inotropic effects of five anaesthetics at equipotent levels.
Topics: Anesthetics; Animals; Cats; Cyclopropanes; Electric Stimulation; Ethyl Ethers; Halothane; Heart; In | 1971 |
Halothane-induced muscle contracture as a cause of hyperpyrexia.
Topics: Adolescent; Contracture; Creatine Kinase; Female; Fever; Halothane; Humans; Male; Muscle Contraction | 1971 |
Myocardial function with halothane anesthesia.
Topics: Anesthesia; Animals; Aorta; Blood Flow Velocity; Dogs; Halothane; Heart; Humans; Muscle Contraction; | 1971 |
Alterations in mechanical properties of heart muscle produced by halothane.
Topics: Animals; Biomechanical Phenomena; Halothane; Heart; In Vitro Techniques; Male; Muscle Contraction; R | 1968 |
Pharmacological interaction between pancuronium bromide and anaesthetics.
Topics: 17-Hydroxycorticosteroids; Androstanes; Anesthesia, Conduction; Animals; Blood Pressure; Bromides; C | 1968 |
Oxygen consumption of human uterine strips. Calculation of a limiting thickness.
Topics: Female; Halothane; Humans; Muscle Contraction; Oxygen Consumption; Refrigeration; Uterus | 1968 |
Tachyphylaxis to decamethonium and reversibility of the block by anticholinesterase drugs.
Topics: Adult; Anesthesia, Endotracheal; Cholinesterase Inhibitors; Decamethonium Compounds; Electric Stimul | 1969 |
Effects of halothane, cyclopropane and nitrous oxide on isolated human uterine muscle.
Topics: Adult; Cyclopropanes; Female; Halothane; Humans; In Vitro Techniques; Middle Aged; Muscle Contractio | 1969 |
A transatlantic studyof neuromuscular blockade.
Topics: Ethanol; Halothane; Humans; London; Muscle Contraction; New York; Nitrous Oxide; Succinylcholine; Th | 1969 |
Drugs acting on the uterus. I.
Topics: Ergonovine; Estrogens; Female; Halothane; Humans; Labor, Induced; Muscle Contraction; Oxytocin; Preg | 1969 |
Ability of glucagon to produce cardiac stimulation without arrhythmias in halothane-anaesthetized animals.
Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Dogs; Epinephrine; Femoral | 1969 |
Actions of halothane and nitrous oxide on dorsal horn neurons ("The Spinal Gate").
Topics: Anesthesia, General; Animals; Blood Pressure; Cats; Electrodes; Electroshock; Female; Foot; Halothan | 1969 |
Comparison of the effects of equieffective concentrations of anesthetics on the force of contraction of isolated perfused rat hearts: correlation with the equieffective anesthetizing partial pressures.
Topics: Anesthesia, Inhalation; Anesthetics; Animals; Chloroform; Cyprinidae; Dogs; Ethyl Ethers; Halothane; | 1969 |
[An objective tinnitus aurium due to periodic clonic contracture of muscles of the soft palate].
Topics: Child; Female; Halothane; Humans; Muscle Contraction; Tinnitus; Uvula | 1965 |
Effect of halothane on neuromuscular transmission.
Topics: Acetylcholine; Animals; Anura; Electrophysiology; Halothane; In Vitro Techniques; Iontophoresis; Mus | 1966 |
Effect of nitrous oxide on myocardial contractility of dogs.
Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Halothane; Heart; Heart Rate; Muscle Contraction; Nit | 1966 |