halothane has been researched along with Liver Diseases in 160 studies
Liver Diseases: Pathological processes of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A series of experiments were conducted to examine the potential role of phase I metabolism in halothane-induced liver injury in the hyperthyroid rat." | 7.67 | Effects of piperonyl butoxide on halothane hepatotoxicity and metabolism in the hyperthyroid rat. ( Berman, LM; Harbison, RD; James, RC; Roberts, SM; Smith, AC, 1988) |
| "Factors affecting halothane (H) hepatotoxicity were investigated in two animal models: 1) the phenobarbital-hypoxia model, and 2) the triiodothyronine (T3) model; in the latter we previously have shown that centrilobular necrosis occurs in T3 pretreated rats anesthetized with 1% H, in 21% oxygen for 2 h." | 7.66 | Contrasting effects on halothane hepatotoxicity in the phenobarbital-hypoxia and triiodothyronine model: mechanistic implications. ( Phythyon, JM; Uetrecht, J; Wood, AJ; Wood, M, 1983) |
| "To evaluate the relative importance of halothane metabolism and liver hypoxia in the occurrence of hepatic injury, the injury produced in hypoxic rats exposed to identical MAC hours of halothane but at various concentrations of halothane was compared." | 7.66 | Hypoxia may be more important than reductive metabolism in halothane-induced hepatic injury. ( Eger, EI; Johnson, BH; Shingu, K, 1982) |
| "Analysis of data derived from 130 reports of jaundice occurring after anaesthesia with halothane showed a significant relation between the number of exposures to this anaesthetic and the rapidity with which jaundice develops after exposure." | 7.65 | Jaundice after repeated exposure to halothane: an analysis of Reports to the Committee on Safety of Medicines. ( Inman, WH; Mushin, WW, 1974) |
| "The liver of all rats given halothane (14% O(2)) had extensive centrilobular necrosis and denaturation." | 3.73 | Ca2+ cytochemical changes of hepatotoxicity caused by halothane and sevoflurane in enzyme-induced hypoxic rats. ( Li, Q; Liu, ZQ; Yang, LQ; Yu, WF; Zhou, MT, 2005) |
| "A series of experiments were conducted to examine the potential role of phase I metabolism in halothane-induced liver injury in the hyperthyroid rat." | 3.67 | Effects of piperonyl butoxide on halothane hepatotoxicity and metabolism in the hyperthyroid rat. ( Berman, LM; Harbison, RD; James, RC; Roberts, SM; Smith, AC, 1988) |
| "To evaluate the importance of hypoxia itself on halothane-induced hepatic injury in the rat, the question of whether hypoxia could injure the liver without causing death was investigated." | 3.66 | Hypoxia per se can produce hepatic damage without death in rats. ( Eger, EI; Johnson, BH; Shingu, K, 1982) |
| "The aetiology of massive liver-cell necrosis which developed in 16 patients following halothane anaesthesia was investigated by means of new serological techniques." | 3.66 | Specific serological markers in the diagnosis of fulminant hepatic failure associated with halothane anaesthesia. ( Davis, M; Gimson, AE; Neuberger, J; Williams, R, 1983) |
| "Factors affecting halothane (H) hepatotoxicity were investigated in two animal models: 1) the phenobarbital-hypoxia model, and 2) the triiodothyronine (T3) model; in the latter we previously have shown that centrilobular necrosis occurs in T3 pretreated rats anesthetized with 1% H, in 21% oxygen for 2 h." | 3.66 | Contrasting effects on halothane hepatotoxicity in the phenobarbital-hypoxia and triiodothyronine model: mechanistic implications. ( Phythyon, JM; Uetrecht, J; Wood, AJ; Wood, M, 1983) |
| "To evaluate the relative importance of halothane metabolism and liver hypoxia in the occurrence of hepatic injury, the injury produced in hypoxic rats exposed to identical MAC hours of halothane but at various concentrations of halothane was compared." | 3.66 | Hypoxia may be more important than reductive metabolism in halothane-induced hepatic injury. ( Eger, EI; Johnson, BH; Shingu, K, 1982) |
| "Hepatic necrosis was induced in rats by a single exposure to 1 per cent halothane in oxygen following pretreatment with a single dose of Aroclor 1254, a polychlorinated biphenyl." | 3.65 | An animal model of hepatotoxicity associated with halothane anesthesia. ( Brown, BR; Sipes, IG, 1976) |
| "Eight pregnant Sprague-Dawley rates were exposed to 10 ppm halothane 8 hours/day and 5 days/week throughout pregnancy." | 3.65 | Ultrastructural evidence of the hepatotoxic effect of halothane in rats following in-utero exposure. ( Chang, LW; Dudley, AW; Katz, J; Lee, YK, 1975) |
| "Extensive infarction of the liver, initially thought to be halothane hepatitis, is described." | 3.65 | Spontaneous hepatic artery thrombosis with infarction of the liver. ( Balint, JA; Buhac, I; OConnor, PJ, 1976) |
| "Analysis of data derived from 130 reports of jaundice occurring after anaesthesia with halothane showed a significant relation between the number of exposures to this anaesthetic and the rapidity with which jaundice develops after exposure." | 3.65 | Jaundice after repeated exposure to halothane: an analysis of Reports to the Committee on Safety of Medicines. ( Inman, WH; Mushin, WW, 1974) |
| "The study concludes that zinc has the potential to alleviate the toxic effects of halothane in rat liver." | 1.35 | Protective role of zinc pretreatment in hepatotoxicity induced by halothane. ( Celik, JB; Esen, H; Otelcioglu, S; Toy, H; Unsal, C, 2008) |
| "The evidence suggests that acute pancreatitis may at times complicate viral hepatitis." | 1.25 | The association of viral hepatitis and acute pancreatitis. ( Geokas, MC; Olsen, H; Rinderknecht, H; Swanson, V, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 148 (92.50) | 18.7374 |
| 1990's | 9 (5.63) | 18.2507 |
| 2000's | 3 (1.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Unsal, C | 1 |
| Celik, JB | 1 |
| Toy, H | 1 |
| Esen, H | 1 |
| Otelcioglu, S | 1 |
| LINDENBAUM, J | 1 |
| LEIFER, E | 1 |
| BUNKER, JP | 1 |
| BLUMENFELD, CM | 1 |
| CHAMBERLAIN, G | 1 |
| KEERI SZANTO, M | 1 |
| LAFLEUR, F | 1 |
| SCHALM, L | 1 |
| POCHYLSKI, T | 1 |
| VICTOROFF, VM | 1 |
| SLATER, EM | 1 |
| GIBSON, JM | 1 |
| DYKES, MH | 2 |
| WALZER, SG | 1 |
| GALVIN, HJ | 2 |
| SHERLOCK, S | 4 |
| GREEN, KG | 1 |
| MUNGAVIN, JM | 1 |
| MUSHIN, WW | 2 |
| ROSEN, M | 1 |
| BOWEN, DJ | 1 |
| CAMPBELL, H | 1 |
| BALESTRA, L | 1 |
| GIARDINA, B | 1 |
| URSO, L | 1 |
| DALMONTE, PR | 1 |
| BRESCHI, F | 1 |
| TURA, S | 1 |
| LOVETT, VF | 1 |
| YAMAUCHI, H | 1 |
| PHILLIPPI, PJ | 1 |
| SMITH, M | 1 |
| READ, AE | 2 |
| GINGRICH, TF | 1 |
| VIRTUE, RW | 1 |
| HILSCHER, A | 1 |
| HUEGIN, W | 1 |
| MOESCHLIN, S | 1 |
| SCHNEIDER, I | 1 |
| BENNIKE, KA | 1 |
| HAGELSTEN, JO | 1 |
| HANSEN, EP | 1 |
| PICHLMAYR, I | 1 |
| PICHLMAYR, R | 1 |
| FREY, R | 1 |
| PEARCE, C | 1 |
| HEYENBROK, WJ | 1 |
| Yu, WF | 1 |
| Yang, LQ | 1 |
| Zhou, MT | 1 |
| Liu, ZQ | 1 |
| Li, Q | 1 |
| You, Q | 1 |
| Cheng, L | 1 |
| Reilly, TP | 1 |
| Wegmann, D | 1 |
| Ju, C | 1 |
| Kiyono, S | 1 |
| Babior, BM | 1 |
| Davidson, CS | 5 |
| Wibert, L | 1 |
| Creutzfeldt, W | 1 |
| Tammisto, T | 1 |
| Tiitinen, P | 1 |
| Elfving, G | 1 |
| Hästbacka, J | 1 |
| Clark, JV | 1 |
| Dundee, JW | 1 |
| Jones, RM | 1 |
| Matsumoto, N | 2 |
| Gaunt, PS | 1 |
| Meuten, DJ | 1 |
| Pecquet-Goad, ME | 1 |
| Harper, MH | 2 |
| Johnson, BH | 5 |
| Eger, EI | 5 |
| Shingu, K | 2 |
| Neuberger, J | 2 |
| Gimson, AE | 2 |
| Davis, M | 2 |
| Williams, R | 7 |
| Uetrecht, J | 1 |
| Wood, AJ | 1 |
| Phythyon, JM | 1 |
| Wood, M | 1 |
| Cousins, MJ | 2 |
| Holzbach, RT | 1 |
| Van Dyke, RA | 2 |
| Wyke, RJ | 1 |
| Canalese, JC | 1 |
| Mieli-Vergani, G | 1 |
| Tredger, JM | 1 |
| Siegers, CP | 1 |
| Mackenroth, T | 1 |
| Wächter, S | 1 |
| Younes, M | 1 |
| Touloukian, J | 1 |
| Kaplowitz, N | 1 |
| Van Pelt, FN | 1 |
| Straub, P | 1 |
| Manns, MP | 1 |
| Groom, S | 1 |
| Checkley, S | 1 |
| Crawford, B | 1 |
| Glasa, J | 1 |
| Turecký, L | 1 |
| Holomán, J | 1 |
| Marcus, C | 1 |
| Kalff, G | 1 |
| Frimmer, M | 1 |
| Homann, J | 1 |
| Rufeger, U | 1 |
| Oldershausen v, HF | 1 |
| Miller, DJ | 1 |
| Cooperman, LH | 1 |
| Wollman, H | 1 |
| Marsh, ML | 1 |
| Lai, MY | 1 |
| Sung, JL | 1 |
| Lin, WS | 1 |
| How, SW | 1 |
| Yu, JY | 1 |
| Wang, TH | 1 |
| Chen, DS | 1 |
| Viegas, O | 1 |
| Stoelting, RK | 1 |
| Miyazaki, T | 1 |
| Nakajima, T | 1 |
| Obi, M | 1 |
| Goto, T | 1 |
| Arima, T | 1 |
| Matsumoto, M | 1 |
| Maruno, Y | 1 |
| Sato, I | 1 |
| Hori, T | 1 |
| Matsumoto, I | 1 |
| Grace, DM | 1 |
| Henderson, AR | 1 |
| Pratilas, V | 1 |
| Pratila, MG | 1 |
| Ross, WT | 1 |
| Sipes, IG | 1 |
| Brown, BR | 1 |
| Olley, SF | 1 |
| Prieto, J | 1 |
| Barry, M | 1 |
| Chang, LW | 1 |
| Lee, YK | 1 |
| Dudley, AW | 1 |
| Katz, J | 1 |
| Laws, I | 1 |
| Kramer, M | 1 |
| L'Allemand, H | 1 |
| Bianchi, L | 2 |
| De Groote, J | 1 |
| Desmet, V | 1 |
| Gedigk, P | 1 |
| Korb, G | 1 |
| Popper, H | 2 |
| Poulsen, H | 1 |
| Scheuer, PJ | 1 |
| Schmid, M | 1 |
| Thaler, H | 1 |
| Wepler, W | 1 |
| Kamel, M | 1 |
| Tewfik, O | 1 |
| Tewfik, HN | 1 |
| OConnor, PJ | 1 |
| Buhac, I | 1 |
| Balint, JA | 1 |
| Giler, S | 1 |
| Ventura, E | 1 |
| Levy, E | 1 |
| Urca, I | 1 |
| Sperling, O | 1 |
| de Vries, A | 1 |
| Mostafapour, S | 1 |
| Marsh, HM | 1 |
| Li, Y | 1 |
| Chopp, M | 1 |
| Lind, RC | 1 |
| Gandolfi, AJ | 1 |
| Hall, PD | 1 |
| McIntyre, N | 1 |
| Wark, H | 1 |
| Earl, J | 1 |
| Cooper, M | 1 |
| Overton, J | 1 |
| Trudell, JR | 1 |
| Ardies, CM | 1 |
| Anderson, WR | 1 |
| O'Grady, JG | 1 |
| Alexander, GJ | 1 |
| Hayllar, KM | 1 |
| Rosenak, D | 1 |
| Halevy, A | 1 |
| Orda, R | 1 |
| Smith, AC | 1 |
| Roberts, SM | 1 |
| Berman, LM | 1 |
| Harbison, RD | 1 |
| James, RC | 1 |
| Lumb, WV | 1 |
| Grandy, JL | 1 |
| Heath, RB | 1 |
| Dunlop, CI | 1 |
| Hodgson, DS | 1 |
| Becker, GL | 1 |
| Miletich, DJ | 1 |
| Albrecht, RF | 1 |
| Hussey, AJ | 1 |
| Howie, J | 1 |
| Allan, LG | 1 |
| Drummond, G | 1 |
| Hayes, JD | 1 |
| Beckett, GJ | 1 |
| James, OF | 1 |
| Smuckler, EA | 2 |
| Ferrell, LD | 2 |
| Goldsmith, CH | 1 |
| Fassoulaki, A | 1 |
| Cahalan, MK | 1 |
| Eger, RR | 1 |
| Plummer, JL | 1 |
| Hall, PM | 1 |
| Jenner, MA | 1 |
| Hillenbrand, P | 1 |
| Klinge, O | 2 |
| Gazzard, BG | 1 |
| Weston, MJ | 1 |
| Murray-Lyon, IM | 1 |
| Flax, H | 1 |
| Record, CO | 1 |
| Portmann, B | 1 |
| Langley, PG | 1 |
| Dunlop, EH | 1 |
| Mellon, PJ | 1 |
| Ward, MB | 1 |
| Smith, JS | 1 |
| Harrison, GG | 1 |
| Freeman, J | 1 |
| Versieck, J | 1 |
| Van Waes, L | 1 |
| Barbier, F | 1 |
| Demeulenaere, L | 1 |
| Vermeire, P | 1 |
| Cohen, AB | 1 |
| Rosenthal, WS | 1 |
| Stenger, RJ | 1 |
| Grimmeisen, H | 1 |
| Clifford, DR | 1 |
| Schöntube, E | 1 |
| Schöntube, M | 1 |
| LaMont, JT | 1 |
| Scholler, KL | 1 |
| Ohnacker, H | 1 |
| Hofstetter, JR | 1 |
| Bruce, DL | 1 |
| Newberry, WM | 1 |
| Shorey, JW | 1 |
| Sanford, JP | 1 |
| Combes, B | 2 |
| Simpson, BR | 1 |
| Strunin, L | 1 |
| Waalton, B | 1 |
| Franken, FH | 1 |
| Goertz, J | 1 |
| Namihisa, T | 1 |
| Yamaguchi, K | 1 |
| Kitami, N | 1 |
| Hussey, HH | 1 |
| Inman, WH | 1 |
| Wilkinson, SP | 1 |
| Blendis, LM | 1 |
| Geall, MG | 1 |
| Webb, MJ | 1 |
| Shigematsu, A | 1 |
| Takahashi, S | 1 |
| Furukawa, T | 1 |
| Little, DM | 1 |
| Trey, C | 3 |
| Okuda, K | 1 |
| Abe, H | 1 |
| Rogers, AI | 1 |
| Cook, GC | 1 |
| Bode, C | 1 |
| Martini, GA | 1 |
| Schaude, G | 1 |
| Siess, M | 1 |
| Vogell, W | 1 |
| Niessing, J | 1 |
| Davis, JE | 1 |
| Karavanov, GG | 1 |
| Borzhievskiĭ, TsK | 1 |
| Korolenko, AM | 1 |
| Schiffer, MA | 1 |
| Dunn, I | 1 |
| Geokas, MC | 1 |
| Olsen, H | 1 |
| Swanson, V | 1 |
| Rinderknecht, H | 1 |
| Holden, TE | 1 |
| Sherline, DM | 1 |
| Winch, J | 1 |
| Caravati, CM | 1 |
| Hooker, TH | 1 |
| Lempinen, M | 1 |
| Collan, Y | 1 |
| Sivula, A | 1 |
| Merikallio, E | 1 |
| Salmenkivi, K | 1 |
| Paloheimo, M | 1 |
| Turunen, MT | 1 |
| Jokinen, EJ | 1 |
| Ahlqvist, J | 1 |
| Farmer, RG | 1 |
| Hawk, WA | 1 |
| Sullivan, BH | 1 |
| Skulberg, A | 1 |
| Endresen, GK | 1 |
| Lund, I | 1 |
| Dordal, E | 1 |
| Glagov, S | 1 |
| Orlando, RA | 1 |
| Platz, C | 1 |
| Clauberg, G | 1 |
| Schwesinger, G | 1 |
| Pink, V | 1 |
| Braune, R | 1 |
| Celary, W | 1 |
| König, G | 1 |
| Pliess, G | 1 |
| Schilling, K | 2 |
| Andreucci, S | 1 |
| Thompson, DS | 1 |
| Eason, CN | 1 |
| Thompson, BW | 1 |
| Robles, C | 1 |
| Mackay, P | 1 |
| Powell, LW | 1 |
| Lipworth, L | 2 |
| Chalmers, TC | 1 |
| Gottlieb, LS | 1 |
| Saunders, SJ | 1 |
| Moses, LE | 1 |
| Mosteller, F | 1 |
| Eger, W | 1 |
| Nassr-Esfahani, H | 1 |
| Schattenfroh, C | 1 |
| Allen, HL | 1 |
| Guerrieri, S | 1 |
| Azzena, GF | 1 |
| Stancanelli, V | 1 |
| Guberti, A | 1 |
| Vos, AK | 1 |
| Galindo, A | 1 |
| Brindle, GF | 1 |
| Gilbert, RG | 1 |
| Rittmeyer, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| 13C-Methacetin Breath Test for the Prediction of Outcome in in Acute Liver Injury or Acute Liver Failure[NCT02786836] | Phase 2/Phase 3 | 76 participants (Actual) | Interventional | 2016-06-10 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The relationship between the cPDR (cumulative PDR of metabolized 13C-Methacetin 20 minutes after ingestion) in single time points of MBT measurements and TFS and non-TFS (death/transplant) at Day 21. (NCT02786836)
Timeframe: The first MBT reading either on Day 1 or Day 2 and Day 21
| Intervention | percentage per hour (Mean) | |
|---|---|---|
| Day 1 or 2 MBT/transplant free survival at Day 21 | Day 1 or 2 MBT & Day 21 non-TFS | |
| 13C-Methacetin Breath Test (MBT) | 1.4 | 0.2 |
Peak PDR is the maximal percent dose recovery (PDR) rate which reflects the maximum rate of metabolism of 13C-methacetin measured as the change in 13CO2 / 12CO2 (normal carbon dioxide) ratio after ingestion of 13C-methacetin normalized using the patient's height and weight. The distributions of mean PDR Peak values were compared between TFS (transplant free survival) and non-TFS (death/transplant) at Day 21. (NCT02786836)
Timeframe: Days 1 and 21
| Intervention | percentage per hour (Mean) | |
|---|---|---|
| Mean Peak PDR for TFS subjects at Day 21 | Mean Peak PDR for non-TFS subjects at Day 21 | |
| 13C-Methacetin Breath Test (MBT) | 10.2 | 1.9 |
This outcome is similar to the peak PDR defined in the primary outcome but as a secondary we are looking at Day 1 or Day 2 peak PDR values. Peak PDR is the maximal percent dose recovery (PDR) rate which reflects the maximum rate of metabolism of 13C-methacetin measured as the change in 13CO2 / 12CO2 ratio after ingestion of 13C-methacetin normalized using the patient's height and weight. The distributions of mean PDR Peak values were compared between TFS and non-TFS (death/transplant) at Day 21. (NCT02786836)
Timeframe: The first MBT reading either on Day 1 or Day 2 and Day 21
| Intervention | percentage per hour (Mean) | |
|---|---|---|
| Day 1 or 2 MBT & Day 21 TFS | Day 1 or 2 MBT & Day 21 non-TFS | |
| 13C-Methacetin Breath Test (MBT) | 9.1 | 2.3 |
29 reviews available for halothane and Liver Diseases
| Article | Year |
|---|---|
[APROPOS OF LIVER DAMAGE BY HALOTHANE. SURVEY OF THE LITERATURE AND PERSONAL INVESTIGATIONS].
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Geriatrics; Halothane; Hepatitis; Liver Diseases | 1964 |
Problems of multiple inhalation anaesthetics.
Topics: Alanine Transaminase; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; gamma-Glutamyl | 1981 |
Clinical comparison of inhalation anaesthetic agents.
Topics: Anesthesia, Inhalation; Cardiovascular Diseases; Coronary Disease; Drug Interactions; Enflurane; Fem | 1984 |
Halothane hepatitis: what's new?
Topics: Animals; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug Interactions; Halothane | 1980 |
Drug-induced liver disease.
Topics: Analgesics; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Chlorpromazine; Contracep | 1981 |
Molecular basis of drug-induced immunological liver injury.
Topics: Animals; Antibody Formation; Anticonvulsants; Chemical and Drug Induced Liver Injury; Dihydralazine; | 1995 |
[The present state of hypotension (author's transl)].
Topics: Cardiac Output; Cerebrovascular Circulation; Coronary Circulation; Ganglionic Blockers; Halothane; H | 1977 |
[Hepatitis-like liver disorders caused by infections, poisoning and drugs].
Topics: Alcoholism; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Cytomegalovirus Infection | 1976 |
Anesthesia and the liver.
Topics: Adolescent; Adult; Aged; Anesthetics; Chemical and Drug Induced Liver Injury; Female; Halothane; Hum | 1977 |
Biochemical and morphological study of the liver injury induced by drugs and chemicals.
Topics: Alkaline Phosphatase; Aspirin; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Halothan | 1979 |
Halothane and the liver: coming of age?
Topics: Anesthesia; Chemical and Drug Induced Liver Injury; Halothane; Hepatitis A; Humans; Liver Diseases; | 1976 |
Hepatobiliary disease: medical emergencies.
Topics: Acetaminophen; Biliary Tract Diseases; Emergencies; Halothane; Hepatic Encephalopathy; Hepatitis, Vi | 1991 |
Halothane and liver damage.
Topics: Adult; Chemical and Drug Induced Liver Injury; Halothane; Humans; Liver Diseases; Male; Middle Aged; | 1989 |
Drugs and the ageing liver.
Topics: Aged; Aging; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Syst | 1985 |
[Anesthesia in liver, gallbladder and biliary tract surgery].
Topics: Analgesia; Anesthesia; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Spinal; Biliary Tract | 1974 |
Hepatic disease and pregnancy.
Topics: Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Contraceptives, Oral; Fatty Liver; Fem | 1973 |
[Chronic exposure to halothane: liver damage in anaesthetists].
Topics: Anesthesiology; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Environmental Expos | 1973 |
What the practicing veterinarian should know about gerbils.
Topics: Anesthesia, Inhalation; Animal Feed; Animals; Bacterial Infections; Blood Cell Count; Breeding; Fema | 1973 |
Immunological liver disease.
Topics: Acidosis, Renal Tubular; Autoimmune Diseases; Chemical and Drug Induced Liver Injury; Cholangiograph | 1973 |
[Halothane syndrome. On the possibility of allergy caused by 1,1,1-trifluor-2-brom-2-chlorethane (Halan) (author's transl)].
Topics: Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Environmental | 1973 |
Postoperative juandice.
Topics: Aminosalicylic Acids; Anemia, Hemolytic; Bile Ducts; Bilirubin; Chemical and Drug Induced Liver Inju | 1974 |
[Anesthesiologic problems in liver diseases].
Topics: Anesthesia; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Spinal; Cholestasis; Germany, Wes | 1974 |
Effects of halothane on hepatic function.
Topics: Age Factors; Alkaline Phosphatase; Anesthesia, General; Anesthesia, Inhalation; Animal Nutritional P | 1968 |
The management of fulminant hepatic failure.
Topics: Acute Disease; Blood Transfusion; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Hal | 1970 |
Causes and effects of acute liver damage.
Topics: Acute Disease; Adrenal Cortex Hormones; Alcoholic Intoxication; Drug Tolerance; Enzyme Induction; Ha | 1970 |
[Recent progress in the study of liver diseases].
Topics: Adrenal Cortex Hormones; Anesthesia, Inhalation; Bilirubin; Biological Transport; Chemical and Drug | 1971 |
Therapeutic considerations in selected forms of acute and chronic liver disease.
Topics: Acute Disease; Age Factors; Alcoholism; Azathioprine; Chemical and Drug Induced Liver Injury; Chroni | 1971 |
Hepatic changes associated with shock.
Topics: Acute Kidney Injury; Animals; Autopsy; Biopsy; Cardiac Surgical Procedures; Halothane; Humans; Isoen | 1969 |
[Toxic liver injury].
Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Cholestyramine Resin; Contraceptives, Oral; Dia | 1970 |
3 trials available for halothane and Liver Diseases
| Article | Year |
|---|---|
Repeated halothane anaesthesia and possible liver damage.
Topics: Adult; Aged; Alkaline Phosphatase; Anesthesia; Halothane; Humans; Liver Diseases; Middle Aged; Trans | 1967 |
An evaluation of the effect of halothane on liver function and disease.
Topics: Alanine Transaminase; Alkaline Phosphatase; Anesthesia; Aspartate Aminotransferases; Bilirubin; Halo | 1967 |
Summary of the national Halothane Study. Possible association between halothane anesthesia and postoperative hepatic necrosis.
Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Barbiturates; Cyclopropanes; Ethers; Female; Haloth | 1966 |
128 other studies available for halothane and Liver Diseases
| Article | Year |
|---|---|
Protective role of zinc pretreatment in hepatotoxicity induced by halothane.
Topics: Anesthetics, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Halothane; Liver Diseases; | 2008 |
Hepatic necrosis associated with halothane anesthesia.
Topics: Anesthesia; Halothane; Humans; Liver Diseases | 1963 |
Liver necrosis after halothane anesthesia. Cause or coincidence?
Topics: Anesthesia; Halothane; Humans; Liver Diseases | 1963 |
Liver damage after halothane anaesthesia.
Topics: Anesthesia; Chemical and Drug Induced Liver Injury; Halothane; Hepatitis; Humans; Liver Diseases | 1963 |
POSTANESTHETIC LIVER COMPLICATIONS IN A GENERAL HOSPITAL: A STATISTICAL STUDY.
Topics: Anesthesia; Anesthesiology; Halothane; Hospitals, General; Liver Diseases; Nitrous Oxide; Postoperat | 1963 |
[LIVER DAMAGE BY DRUGS].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Arsphenamine; Chemical and Drug Induced Liver Injury; Chl | 1963 |
[USEFULNESS OF FLUOTHANE IN ANESTHESIA OF PATIENTS WITH JAUNDICE AND LIVER LESIONS].
Topics: Anesthesia; Anesthesia, Inhalation; Halothane; Humans; Jaundice; Liver Diseases | 1963 |
LIVER NECROSIS AFTER HALOTHANE ANESTHESIA--POST HOC, ERGO PROPTER HOC?
Topics: Accidents; Accidents, Occupational; Anesthesia; Anesthesia, Inhalation; Anesthesiology; Halothane; H | 1963 |
POSTOPERATIVE HEPATIC NECROSIS. ITS INCIDENCE AND DIAGNOSTIC VALUE IN ASSOCIATION WITH THE ADMINISTRATION OF HALOTHANE.
Topics: Chemical and Drug Induced Liver Injury; Cyclopropanes; Diagnosis, Differential; Geriatrics; Halothan | 1964 |
LIVER DAMAGE AND FLUOTHANE.
Topics: Chemical and Drug Induced Liver Injury; Halothane; Hepatitis; Liver Diseases; Toxicology; Viral Vacc | 1964 |
HALOTHANE AND THE LIVER.
Topics: Chemical and Drug Induced Liver Injury; Chloroform; Halothane; Hepatitis; Jaundice; Liver Diseases; | 1964 |
HALOTHANE AND THE LIVER: RETROSPECTIVE STUDIES.
Topics: Chemical and Drug Induced Liver Injury; Halothane; Hepatitis A; Liver Diseases; Necrosis; Retrospect | 1964 |
HALOTHANE AND LIVER DYSFUNCTION: A RETROSPECTIVE STUDY.
Topics: Alanine Transaminase; Alkaline Phosphatase; Anesthesia; Anesthesia, General; Aspartate Aminotransfer | 1964 |
[COMPARATIVE EXPERIMENTAL STUDY OF THE HISTOLOGICAL CHANGES IN THE LIVER AND KIDNEY IN ACUTE POISONING BY CHLOROFORM, FLUOTHANE AND METHOCYFLURANE].
Topics: Anesthetics; Chemical and Drug Induced Liver Injury; Chloroform; Halothane; Hepatitis; Kidney; Kidne | 1964 |
[FUNCTIONAL AND BIOPTIC STUDY OF THE LIVER IN PATIENTS EXPOSED TO FLUOTHANE ANESTHESIA].
Topics: Alanine Transaminase; Alkaline Phosphatase; Anesthesia; Aspartate Aminotransferases; Chemical and Dr | 1964 |
HEMODIALYSIS IN THE TREATMENT OF POSTOPERATIVE ACUTE RENAL FAILURE ASSOCIATED WITH JAUNDICE: A REPORT OF THREE CASES.
Topics: Acute Kidney Injury; Bilirubin; Biopsy; Cholecystectomy; Creatine; Creatinine; Halothane; Humans; Ja | 1964 |
THE CONTRIBUTION OF HALOTHANE TO ANAESTHESIA.
Topics: Adjuvants, Anesthesia; Anesthesia; Anesthesiology; Bronchodilator Agents; Epinephrine; Halothane; Hy | 1964 |
LIVER DAMAGE AND HALOTHANE.
Topics: Abdominal Injuries; Accidents; Accidents, Traffic; Halothane; Intestinal Obstruction; Liver Diseases | 1964 |
DRUGS AND LIVER DISEASE.
Topics: Androgens; Anti-Bacterial Agents; Antihypertensive Agents; Antineoplastic Agents; Arsphenamine; Chem | 1965 |
POSTOPERATIVE LIVER DAMAGE: IS ANESTHESIA INVOLVED?
Topics: Anesthesia; Anesthetics; Chemical and Drug Induced Liver Injury; Geriatrics; Halogens; Halothane; He | 1965 |
[ONCE AGAIN: ACUTE MASSIVE NECROSIS OF THE LIVER AFTER HALOTHANE ANESTHESIA].
Topics: Anesthesia; Halothane; Liver Diseases; Necrosis; Toxicology | 1965 |
[HALOTHANE AND LIVER DAMAGE].
Topics: Anesthesia; Chemical and Drug Induced Liver Injury; Halothane; Hepatitis; Hepatitis A; Liver Disease | 1965 |
[ACUTE LIVER DYSTROPHY IN AN INFANT AFTER HALOTHANE ANESTHESIA].
Topics: Anesthesia; Halothane; Humans; Infant; Liver Diseases; Toxicology | 1965 |
[LIVER DISORDERS AFTER HALOTHANE ANESTHESIA--POST OR PROPTER?].
Topics: Anesthesia; Anesthesiology; Chemical and Drug Induced Liver Injury; Halothane; Hepatitis; Liver Dise | 1964 |
[HALOTHANE AND LIVER DAMAGE].
Topics: Chemical and Drug Induced Liver Injury; Halothane; Hepatitis; Liver Diseases; Postoperative Complica | 1964 |
[LIVER DAMAGE CAUSED BY HALOTHANE].
Topics: Abdominal Injuries; Chemical and Drug Induced Liver Injury; Halothane; Hepatitis; Liver Diseases; To | 1965 |
Ca2+ cytochemical changes of hepatotoxicity caused by halothane and sevoflurane in enzyme-induced hypoxic rats.
Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Calcium; Chemical and Drug Induced Liver Inj | 2005 |
Role of neutrophils in a mouse model of halothane-induced liver injury.
Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Fluoroacetates; Hal | 2006 |
[Anesthesia for patients with hepatic disorders].
Topics: Anesthesia; Halothane; Humans; Japan; Liver; Liver Diseases; Liver Function Tests | 1966 |
Postoperative massive liver necrosis. A clinical and pathological study.
Topics: Cardiovascular Diseases; Halothane; Hepatitis; Humans; In Vitro Techniques; Liver Diseases; Necrosis | 1967 |
[Recurrent jaundice with fatal liver necrosis after halothane anesthesia performances].
Topics: Anesthesia, General; Gastrectomy; Halothane; Humans; Jaundice; Liver Diseases; Male; Middle Aged; Ne | 1967 |
A case of acute yellow atrophy of the liver.
Topics: Diagnosis, Differential; Female; Halothane; Hepatitis A; Humans; Liver Diseases; Middle Aged | 1967 |
[Hepatic circulation, metabolism and damage during halothane anesthesia].
Topics: Anesthesia, Inhalation; Animals; Dogs; Halothane; Liver; Liver Circulation; Liver Diseases; Oxygen C | 1983 |
Hepatic necrosis associated with use of halothane in a dog.
Topics: Anesthesia, General; Animals; Chemical and Drug Induced Liver Injury; Dog Diseases; Dogs; Halothane; | 1984 |
Celiac plexus block does not alter hepatic injury in rats.
Topics: Anesthetics; Animals; Bupivacaine; Celiac Plexus; Chemical and Drug Induced Liver Injury; Drug Inter | 1984 |
Hypoxia per se can produce hepatic damage without death in rats.
Topics: Animals; Carbon Dioxide; Chemical and Drug Induced Liver Injury; Halothane; Hypoxia; Liver Diseases; | 1982 |
Specific serological markers in the diagnosis of fulminant hepatic failure associated with halothane anaesthesia.
Topics: Acute Disease; Adolescent; Adult; Aged; Anesthesia, Inhalation; Antibodies; Chemical and Drug Induce | 1983 |
Contrasting effects on halothane hepatotoxicity in the phenobarbital-hypoxia and triiodothyronine model: mechanistic implications.
Topics: Animals; Chemical and Drug Induced Liver Injury; Fasting; Fluorides; Halothane; Hypoxia; Liver Disea | 1983 |
Hepatic centrilobular necrosis in rats after exposure to halothane, enflurane, or isoflurane.
Topics: Animals; Chemical and Drug Induced Liver Injury; Enflurane; Glutathione; Halothane; Isoflurane; Live | 1982 |
Hypoxia may be more important than reductive metabolism in halothane-induced hepatic injury.
Topics: Animals; Chemical and Drug Induced Liver Injury; Fasting; Halothane; Hypoxia; Liver; Liver Diseases; | 1982 |
Bacteraemia in patients with fulminant hepatic failure.
Topics: Acetaminophen; Adolescent; Adult; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; H | 1982 |
Oxidative metabolism of halothane in the production of altered hepatocyte membrane antigens in acute halothane-induced hepatic necrosis.
Topics: Animals; Antigens, Surface; Chemical and Drug Induced Liver Injury; Cytotoxicity, Immunologic; Femal | 1981 |
Effects of liver injury and cholestasis on microsomal enzyme activities and metabolism of halothane, enflurane and methoxyflurane in vivo in rats.
Topics: Anesthetics; Animals; Carbon Tetrachloride Poisoning; Cholestasis; Enflurane; Half-Life; Halothane; | 1981 |
Halothane-induced hepatic disease.
Topics: Adolescent; Adult; Age Factors; Aged; Chemical and Drug Induced Liver Injury; Diagnosis, Differentia | 1981 |
Hepatic necrosis associated with halothane anesthesia in an alpaca.
Topics: Anesthesia, Inhalation; Animals; Camelids, New World; Chemical and Drug Induced Liver Injury; Haloth | 1995 |
[Evaluation of hepatic damage in personnel in the anesthesiology- resuscitation department in relation to halothane exposure].
Topics: Adult; Anesthesiology; Chemical and Drug Induced Liver Injury; Female; Halothane; Health Personnel; | 1993 |
Postoperative hepatic dysfunction in perspective. 1970.
Topics: Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Halothane; History, 20th Century; H | 1998 |
[Inhibition by diethyldithiocarbamate (DEDTC) of acute hepatotoxic effects induced by polyhalogenated hydrocarbons (PHHC)].
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Ditioca | 1976 |
Studies in clinical liver disease.
Topics: Adult; Autoantibodies; Bacterial Infections; Biopsy; Chemical and Drug Induced Liver Injury; Cholest | 1979 |
LDH5 changes after cholecystectomy or hysterectomy in patients receiving halothane, enflurane, or fentanyl.
Topics: Adult; Cholecystectomy; Enflurane; Female; Fentanyl; Halothane; Humans; Hysterectomy; Isoenzymes; L- | 1979 |
[Anesthesia and liver function -- changes of serum LDH isozyme pattern (author's transl)].
Topics: Anesthesia; Biliary Tract Diseases; Halothane; Humans; Isoenzymes; L-Lactate Dehydrogenase; Liver; L | 1979 |
Preoperative and postoperative enzyme changes in patients with gallstones.
Topics: Adolescent; Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Child; C | 1978 |
Are effects of halothane on hepatocytes "pathologic".
Topics: Animals; Chemical and Drug Induced Liver Injury; Halothane; Liver; Liver Diseases; Rats | 1977 |
An animal model of hepatotoxicity associated with halothane anesthesia.
Topics: Anesthesia, Inhalation; Animals; Aroclors; Biotransformation; Chemical and Drug Induced Liver Injury | 1976 |
Acute hepatic failure and Henoch-Schönlein syndrome appearing in a patient with severe cranio-facial injuries.
Topics: Acute Disease; Adult; Anesthesia, General; Facial Injuries; Halothane; Humans; IgA Vasculitis; Liver | 1976 |
Serum ferritin in patients with iron overload and with acute and chronic liver diseases.
Topics: Acetaminophen; Alcoholism; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Drug | 1975 |
Ultrastructural evidence of the hepatotoxic effect of halothane in rats following in-utero exposure.
Topics: Animals; Animals, Newborn; Chemical and Drug Induced Liver Injury; Cytoplasm; Environmental Pollutan | 1975 |
Medical risks and dental anaesthetics.
Topics: Analgesics; Anesthesia, Dental; Anesthesia, General; Anesthesia, Local; Anti-Bacterial Agents; Antic | 1975 |
[Experimental studies in animals on the question of liver damage following halothane anaesthesia and hypoxia (author's transl)].
Topics: Alanine Transaminase; Anesthesia, Inhalation; Animals; Aspartate Aminotransferases; Cholinesterases; | 1975 |
[Rules for the histological evaluation of drug-induced liver lesions].
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholestasis; Contraceptives, Oral; F | 1975 |
Disturbance of hepatic structure under halothane anaesthesia.
Topics: Anesthesia, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Halothane; Liver Diseases; | 1975 |
Spontaneous hepatic artery thrombosis with infarction of the liver.
Topics: Aged; Amputation, Surgical; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Diagnosi | 1976 |
Elevation of serum xanthine oxidase following halothane anesthesia in the rat.
Topics: Anesthesia, General; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; F | 1976 |
Immunocytochemical detection of the 72-kDa heat shock protein in halothane--induced hepatotoxicity in rats.
Topics: Animals; Antibodies, Monoclonal; Chemical and Drug Induced Liver Injury; Halothane; Heat-Shock Prote | 1992 |
Subanesthetic halothane is hepatotoxic in the guinea pig.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, D | 1992 |
Halothane in children with chronic liver disease.
Topics: Adolescent; Anesthesia, Inhalation; Child; Child, Preschool; Chronic Disease; Female; Halothane; Hum | 1991 |
The effect of alcohol and anesthetic metabolites on cell membranes. A possible direct immune mechanism.
Topics: Acetaldehyde; Alcoholism; Animals; Antibody Formation; Cell Membrane; Chemical and Drug Induced Live | 1991 |
Early indicators of prognosis in fulminant hepatic failure.
Topics: Acetaminophen; Adult; Chemical and Drug Induced Liver Injury; Child; Drug Hypersensitivity; Halothan | 1989 |
Effects of piperonyl butoxide on halothane hepatotoxicity and metabolism in the hyperthyroid rat.
Topics: Administration, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Cy | 1988 |
Clinical report, "Hepatic necrosis following halothane anesthesia in goats," viewed as unacceptable.
Topics: Animals; Chemical and Drug Induced Liver Injury; Goats; Halothane; Liver Diseases; Necrosis | 1987 |
Halogenated anesthetics increase oxygen consumption in isolated hepatocytes from phenobarbital-treated rats.
Topics: Anesthetics; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 En | 1987 |
Impaired hepatocellular integrity during general anaesthesia, as assessed by measurement of plasma glutathione S-transferase.
Topics: Adult; Aged; Aged, 80 and over; Alanine Transaminase; Chemical and Drug Induced Liver Injury; Female | 1986 |
Is enflurane hepatotoxic?
Topics: Adult; Chemical and Drug Induced Liver Injury; Enflurane; Female; Halothane; Humans; Liver Diseases; | 1986 |
Nitrous oxide does not hinder the repair of halothane-induced hepatic injury in the rat.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Bretylium Compounds; Chemical an | 1985 |
Sex differences in halothane metabolism and hepatotoxicity in a rat model.
Topics: Alanine Transaminase; Anesthesia, Inhalation; Animals; Biotransformation; Breath Tests; Chemical and | 1985 |
Use of Normotest and Thrombotest, coagulation tests in hepatocellular disease.
Topics: Acute Disease; Adolescent; Adult; Aged; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin | 1973 |
[Morphology and etiology of halothane-induced liver lesions (author's transl)].
Topics: Adult; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Child; Cholestasis; Fatty Liv | 1972 |
Charcoal haemoperfusion in the treatment of fulminant hepatic failure.
Topics: Adolescent; Adult; Amino Acids; Autopsy; Biopsy, Needle; Blood; Blood Cell Count; Blood Coagulation; | 1974 |
The effects of multiple anaesthetics on the livers of rats subjected to microsomal enzyme induction. A preliminary report.
Topics: Anesthetics; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Enzyme | 1973 |
Peritoneoscopy during hepatic coma.
Topics: Adolescent; Adult; Aged; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Haloth | 1973 |
Autoimmune response in experimental halothan-induced liver injury.
Topics: Animals; Antibody Formation; Autoantibodies; Chemical and Drug Induced Liver Injury; Dose-Response R | 1973 |
[Drugs and the liver].
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Enzyme Induction; Halothane; Humans; Liver; Liver Di | 1972 |
[Postoperative jaundice].
Topics: Female; Halothane; Humans; Jaundice; Liver Diseases; Middle Aged; Postoperative Complications | 1972 |
What is a "safe" interval between halothane exposures?
Topics: Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Halothane; Humans; Liver; Liver Dise | 1972 |
Depression of lymphocyte reactivity to phytohemagglutinin by serum from patients with liver disease.
Topics: Bile Acids and Salts; Carrier State; Chemical and Drug Induced Liver Injury; Cholelithiasis; Halotha | 1973 |
Halothane hepatitis--fact or fallacy.
Topics: Antibodies; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Drug Hypersensitivity; | 1973 |
[Sedatives and liver diseases].
Topics: Barbiturates; Chemical and Drug Induced Liver Injury; Cholestasis; Halothane; Humans; Hypnotics and | 1973 |
Histological appearances in fulminant hepatic failure with reference to aetiology, time of survival and role of immunological processes.
Topics: Acetaminophen; Adolescent; Adult; Aged; Cell Nucleus; Chemical and Drug Induced Liver Injury; Haloth | 1973 |
[Hepatic disorder associated with halothane anesthesia: diagnosis based on RNA synthesis by the peripheral lymphocytes].
Topics: Adult; Anesthesia, General; Chemical and Drug Induced Liver Injury; Female; Halothane; Humans; Liver | 1973 |
Editorial: Fulminant hepatic failure.
Topics: Age Factors; Aged; Anesthesia; Calcium; Chemical and Drug Induced Liver Injury; Exchange Transfusion | 1973 |
Jaundice after repeated exposure to halothane: an analysis of Reports to the Committee on Safety of Medicines.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Anesthesia, Inhalation; England; Female; Haloth | 1974 |
Frequency and type of renal and electrolyte disorders in fulminant hepatic failure.
Topics: Acetaminophen; Acute Kidney Injury; Blood Glucose; Chemical and Drug Induced Liver Injury; Creatinin | 1974 |
Liver disease in pregnancy.
Topics: Acute Kidney Injury; Chemical and Drug Induced Liver Injury; Cholestasis; Contraceptives, Oral; Fatt | 1974 |
[Microsomal mixed function oxidation and oxygen partial pressure--relationship between hypoxia and liver injuries by halothane].
Topics: Animals; Chemical and Drug Induced Liver Injury; Halothane; Hypoxia; Liver Diseases; Male; Microsome | 1974 |
[Histological, histochemical and electron microscopical findings in foreign substance induced liver hypertrophy in white mice].
Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroform; Endoplasmic Reticulum; Halothane; Hyper | 1967 |
Fatal hepatic necrosis associated with halothane anesthesia.
Topics: Adult; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Female; Halothane; Hepatitis; | 1972 |
[A comparative evaluation of the effects of different kinds of anesthesia on the liver as judged by sorbitol dehydrogenase activity].
Topics: Adult; Alcohol Oxidoreductases; Anesthesia, General; Chemical and Drug Induced Liver Injury; Chlorof | 1972 |
[The relationship between electron microscopic changes in the liver and anesthesia with fluothane and trilene].
Topics: Anesthesia, General; Animals; Halothane; Liver Diseases; Microscopy, Electron; Rats; Trichloroethyle | 1972 |
Jaundice with hepatorenal failure associated with pregnancy or gynologic procedures.
Topics: Acute Kidney Injury; Adult; Autopsy; Blood Urea Nitrogen; Fatty Liver; Female; Halothane; Hepatitis | 1972 |
The association of viral hepatitis and acute pancreatitis.
Topics: Adult; Aged; Autolysis; Autopsy; Child, Preschool; Female; Halothane; Hepatitis A; Humans; Liver Dis | 1972 |
Hepatitis and hepatic failure in pregnancy.
Topics: Cholestasis; Fatty Liver; Female; Halothane; Hepatitis; Hepatitis A; Hepatitis B; Hepatitis B Antige | 1972 |
A model which can be used to improve the treatment of acute hepatic failure.
Topics: Albumins; Anesthesia, General; Animals; Biotransformation; Blood Coagulation; Blood Pressure; Fibrin | 1972 |
Acute massive hepatic necrosis with fatal liver failure.
Topics: Acute Disease; Adolescent; Adult; Aged; Anticonvulsants; Antitubercular Agents; Azathioprine; Blood | 1971 |
Pig-liver perfusion. Extracorporeal pig-liver perfusion in a patient with acute hepatic failure.
Topics: Adult; Ammonia; Anesthesia, Inhalation; Animals; Autopsy; Bilirubin; Biopsy; Embolism; Female; Halot | 1971 |
Dubin-Johnson syndrome with varied manifestations. Report of two cases.
Topics: Adolescent; Anesthesia, Inhalation; Bilirubin; Biopsy; Diagnosis, Differential; Halothane; Humans; H | 1971 |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 10-1970.
Topics: Aged; Autopsy; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Female; Halothane; H | 1970 |
Halothane and liver damage.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Halothane; Human | 1970 |
Fatal halothane hepatitis with transient granulomas.
Topics: Adult; Anesthesia, Inhalation; Autopsy; Biopsy; Chemical and Drug Induced Liver Injury; Drug Hyperse | 1970 |
[Studies on the influence of inhalation anesthesia and surgery on liver function with special reference to halothane].
Topics: Anesthesia, Inhalation; Anesthetics; Animals; Chloroform; Enzyme Activation; Enzyme Induction; Halot | 1970 |
[Postoperative toxic liver disease].
Topics: Aged; Autopsy; Chemical and Drug Induced Liver Injury; Cholecystectomy; Cholelithiasis; Female; Halo | 1971 |
[Liver cell damage in surgery].
Topics: Aged; Anesthesia, Inhalation; Arteriosclerosis; Colonic Neoplasms; Duodenal Ulcer; Female; Halothane | 1967 |
[Evaluation of the hepatic functional lesion in fluothane anesthesia by means of determination of the Quick time].
Topics: Adolescent; Adult; Anesthesia; Child; Halothane; Humans; Liver Diseases; Liver Function Tests; Middl | 1967 |
[Halothane and hepatic necrosis].
Topics: Adult; Anesthesia, Endotracheal; Halothane; Humans; Liver Diseases; Male; Necrosis | 1967 |
Halothane and liver injury.
Topics: Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Halothane; Humans; Liver; Liver Dise | 1968 |
Anaesthesia and liver function.
Topics: Anesthesia, General; Anesthetics; Bilirubin; Halothane; Humans; Liver; Liver Diseases | 1968 |
Fulminant hepatic failure. Presumable contribution to halothane.
Topics: Acute Disease; Adolescent; Adult; Aged; Aminosalicylic Acids; Chemical and Drug Induced Liver Injury | 1968 |
Massive hepatic necrosis following multiple exposures to halothane.
Topics: Aged; Brain; Diagnosis, Differential; Female; Halothane; Hemorrhage; Humans; Kidney; Kidney Diseases | 1968 |
Institutional differences in Postoperative death rates. Commentary on some of the findings of the National Halothane Study.
Topics: Anesthesia, General; Cystoscopy; Female; Femoral Fractures; Gallbladder; Gastrectomy; Halothane; Hos | 1968 |
[Postoperative liver lesions and halothane anesthesia].
Topics: Anesthesia; Animals; Chemical and Drug Induced Liver Injury; Ethyl Ethers; Female; Halothane; Humans | 1968 |
Halothane-induced liver damage--an entity.
Topics: Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Halothane; Humans; Liver; Liver Disea | 1969 |
Halothane and liver damage.
Topics: Chemical and Drug Induced Liver Injury; Halothane; Humans; Liver Diseases | 1969 |
Halothane and liver damage.
Topics: Africa, Southern; Chemical and Drug Induced Liver Injury; Halothane; Humans; Jaundice; Liver Disease | 1969 |
[Clinical uses of the hypotensive action of fluothane].
Topics: Angiography; Cerebrovascular Disorders; Coronary Disease; Halothane; Humans; Hypotension, Controlled | 1969 |
[Acute liver cell necrosis].
Topics: Adult; Barbiturates; Chemical and Drug Induced Liver Injury; Female; Halothane; Humans; Liver; Liver | 1969 |
Drug impurities.
Topics: Halothane; Humans; Liver Diseases | 1965 |
[Toxic hepatosis in halothane anesthesia].
Topics: Adult; Aged; Biopsy; Female; Halothane; Humans; Liver; Liver Diseases; Middle Aged | 1965 |
Hepatic circulation and hepatic function during anaesthesia and surgery. IV. Halothane anaesthesia.
Topics: Acidosis; Anesthesia; Animals; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Chloroform; Dogs | 1966 |
[Findings following isolated perfusion of the liver with halothane].
Topics: Anesthesia, General; Animals; Chemotherapy, Cancer, Regional Perfusion; Female; Halothane; Liver; Li | 1966 |