halothane has been researched along with Leukemia P388 in 1 studies
Leukemia P388: An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The LD50 (30 day) for cyclophosphamide without halothane was 251 mg/kg; with 2 h subsequent exposure to halothane it was 152 mg/kg; and with 20 h subsequent exposure to halothane it was 158 mg/kg." | 1.27 | Increased toxicity of the antitumor drug cyclophosphamide in mice in the presence of the volatile anesthetic agent halothane. ( Kooistra, KL; Powis, G; Rosenow, S; Van Dyke, RA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rosenow, S | 1 |
| Kooistra, KL | 1 |
| Powis, G | 1 |
| Van Dyke, RA | 1 |
1 other study available for halothane and Leukemia P388
| Article | Year |
|---|---|
Increased toxicity of the antitumor drug cyclophosphamide in mice in the presence of the volatile anesthetic agent halothane.
Topics: Animals; Brain; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Dose-Resp | 1986 |