Page last updated: 2024-10-28

halothane and Kidney Diseases

halothane has been researched along with Kidney Diseases in 55 studies

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"Carbon dioxide absorbents degrade both halothane and sevoflurane to toxic unsaturated compounds (CF2=CBrCl and CH2F-O-C[=CF2][CF3] [i."1.30Quantitative differences in the production and toxicity of CF2=BrCl versus CH2F-O-C(=CF2)(CF3) (compound A): the safety of halothane does not indicate the safety of sevoflurane. ( Eger, EI; Gong, D; Ionescu, P; Kerschmann, RL; Laster, MJ; Weiskopf, RB, 1997)
" The LD50 (30 day) for cyclophosphamide without halothane was 251 mg/kg; with 2 h subsequent exposure to halothane it was 152 mg/kg; and with 20 h subsequent exposure to halothane it was 158 mg/kg."1.27Increased toxicity of the antitumor drug cyclophosphamide in mice in the presence of the volatile anesthetic agent halothane. ( Kooistra, KL; Powis, G; Rosenow, S; Van Dyke, RA, 1986)

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-199050 (90.91)18.7374
1990's4 (7.27)18.2507
2000's0 (0.00)29.6817
2010's1 (1.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Orhan, H1
Sahin, A1
Sahin, G1
Aypar, U1
Vermeulen, NP1
KERBEL, NC1
HILLIARD, IM1
LEHNER, T1
BALESTRA, L1
GIARDINA, B1
SCHOEFFEL, ME1
AREAN, VM1
GRAVENSTEIN, JS2
Marier, JR1
Jones, RM1
Jurdi-Nuwayhid, F1
Spingler, A1
Schunk, W1
Green, CJ1
Manley, SV1
McDonell, WN1
Gelman, ML1
Lichtenstein, NS1
Van Dyke, RA2
Sinclair, M1
Fish, K1
Sievenpiper, T1
Rice, SA2
Wharton, RS1
Mazze, RI5
Eger, EI1
Ionescu, P1
Laster, MJ1
Gong, D1
Weiskopf, RB1
Kerschmann, RL1
Bito, H1
Conway, CM1
Cohen, EN1
Bonora, M1
Novello, F1
Bonetti, E1
Cetrullo, C1
Sievenpiper, TS1
McClendon, F1
Kosek, JC1
Hitt, BA1
Chang, LW3
Blaum, U1
Pflüger, H1
Katz, J2
Kemi, C1
Yanagida, H1
Yamamura, H1
Parker, CW1
Laws, I1
Dudley, AW1
lee, YK1
Hayden, PJ1
Ichimura, T1
McCann, DJ1
Pohl, LR1
Stevens, JL1
Tuman, KJ1
McCarthy, RJ1
Spiess, BD1
Ivankovich, AD1
Peduto, VA1
Napoleone, M1
Rosenow, S1
Kooistra, KL1
Powis, G1
Plummer, JL1
Hall, PD1
Jenner, MA1
Ilsley, AH1
Cousins, MJ2
Kevy, SV1
Britt, BA1
Kalow, W1
Gottlieb, LS1
Trey, C1
McLaughlin, AP1
Altwein, JE1
Kessler, WO1
Gittes, RF1
Wilkinson, SP1
Blendis, LM1
Williams, R1
Joshi, PH1
Conn, HO1
Hamilton, WF2
Robertson, GS2
Granberg, PO1
Lundberg, S1
Cascorbi, HF1
Nishimura, TG1
Adriani, J1
Yarbrough, WM1
Shue, GL1
Jackson, SH1
Lebeau, R1
Damir, EA1
Burov, NE1
Stoelting, RK1
Kim, M1
Gauert, WB1
Schloerb, PR1
Guerrieri, S1
Azzena, GF1
Stancanelli, V1
Guberti, A1

Reviews

13 reviews available for halothane and Kidney Diseases

ArticleYear
Halogenated hydrocarbon environmental pollution: the special case of halogenated anesthetics.
    Environmental research, 1982, Volume: 28, Issue:1

    Topics: Anesthetics; Chemical and Drug Induced Liver Injury; Ethers; Halothane; Health Occupations; Humans;

1982
Clinical comparison of inhalation anaesthetic agents.
    British journal of anaesthesia, 1984, Volume: 56 Suppl 1

    Topics: Anesthesia, Inhalation; Cardiovascular Diseases; Coronary Disease; Drug Interactions; Enflurane; Fem

1984
[The physical health of personnel exposed to halothane in operating rooms].
    Zeitschrift fur die gesamte Hygiene und ihre Grenzgebiete, 1980, Volume: 26, Issue:1

    Topics: Anesthesiology; Chemical and Drug Induced Liver Injury; Halothane; Heart Diseases; Humans; Kidney Di

1980
Anaesthetic gases and health risks to laboratory personnel: a review.
    Laboratory animals, 1981, Volume: 15, Issue:4

    Topics: Abnormalities, Drug-Induced; Anesthesia, Inhalation; Anesthetics; Animals; Chemical and Drug Induced

1981
[Metabolism and toxicity of anesthetics].
    Masui. The Japanese journal of anesthesiology, 1999, Volume: 48 Suppl

    Topics: Anesthetics, Inhalation; Carbon Monoxide Poisoning; Chemical and Drug Induced Liver Injury; Enfluran

1999
Toxicity of inhalation anaesthetic agents.
    British journal of anaesthesia, 1978, Volume: 50, Issue:7

    Topics: Anesthesia, Inhalation; Anesthetics; Animals; Chemical and Drug Induced Liver Injury; Drug Hypersens

1978
Pathologic effects of chronic halothane inhalation: an overview.
    Anesthesiology, 1976, Volume: 45, Issue:6

    Topics: Anesthesia, Inhalation; Animals; Brain; Brain Diseases; Chemical and Drug Induced Liver Injury; Envi

1976
[Anesthesiologists and the environment in the operation room].
    Masui. The Japanese journal of anesthesiology, 1975, Volume: 24, Issue:1

    Topics: Abortion, Spontaneous; Air Microbiology; Air Pollution; Anesthesiology; Anesthetics; Arrhythmias, Ca

1975
[Poisoning caused by chronic exposure to volatile anesthetics. Molecular mechanisms and risk anesthetics].
    Minerva anestesiologica, 1989, Volume: 55, Issue:12

    Topics: Air Pollutants, Occupational; Biodegradation, Environmental; Bromides; Chemical and Drug Induced Liv

1989
Malignant hyperthermia: a statistical review.
    Canadian Anaesthetists' Society journal, 1970, Volume: 17, Issue:4

    Topics: Acidosis; Acidosis, Respiratory; Adolescent; Adult; Anesthesia, General; Anesthesia, Inhalation; Bio

1970
The effects of fluorinated anesthetics on the liver and kidneys.
    Annual review of medicine, 1974, Volume: 25

    Topics: Acute Kidney Injury; Adult; Anesthesia, Inhalation; Animals; Biotransformation; Chemical and Drug In

1974
Renal circulation in association with anesthesia and operation and during the postoperative stage.
    International anesthesiology clinics, 1969,Summer, Volume: 7, Issue:2

    Topics: Adjuvants, Anesthesia; Anesthesia, Conduction; Anesthesia, Inhalation; Anesthesia, Intravenous; Anes

1969
[Parenchymal damage following Halothane and Methoxyflurane].
    Der Anaesthesist, 1971, Volume: 20, Issue:11

    Topics: Anesthesia, Inhalation; Biotransformation; Chemical and Drug Induced Liver Injury; Chemical Phenomen

1971

Trials

2 trials available for halothane and Kidney Diseases

ArticleYear
Urinary lipid and protein oxidation products upon halothane, isoflurane, or sevoflurane anesthesia in humans: potential biomarkers for a subclinical nephrotoxicity.
    Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2013, Volume: 18, Issue:1

    Topics: Acetone; Aldehydes; Anesthetics, Inhalation; Biomarkers; Female; Glycosuria; Halothane; Humans; Isof

2013
Renal dysfunction associated with methoxyflurane anesthesia. A randomized, prospective clinical evaluation.
    JAMA, 1971, Apr-12, Volume: 216, Issue:2

    Topics: Adult; Aged; Anesthetics; Blood Urea Nitrogen; Body Weight; Creatinine; Halothane; Humans; Hypernatr

1971

Other Studies

40 other studies available for halothane and Kidney Diseases

ArticleYear
HALOTHANE HEPATOTOXICITY.
    Canadian Medical Association journal, 1963, Nov-02, Volume: 89

    Topics: Anesthesia; Anesthesia, Inhalation; Anesthesia, Obstetrical; Aspartate Aminotransferases; Blood Chem

1963
SYSTEMIC CANDIDIASIS AND RENAL INVOLVEMENT.
    Lancet (London, England), 1964, Jun-27, Volume: 2, Issue:7348

    Topics: Anti-Bacterial Agents; Candidiasis; Chemical and Drug Induced Liver Injury; Chloramphenicol; Diagnos

1964
[COMPARATIVE EXPERIMENTAL STUDY OF THE HISTOLOGICAL CHANGES IN THE LIVER AND KIDNEY IN ACUTE POISONING BY CHLOROFORM, FLUOTHANE AND METHOCYFLURANE].
    Minerva anestesiologica, 1964, Volume: 30

    Topics: Anesthetics; Chemical and Drug Induced Liver Injury; Chloroform; Halothane; Hepatitis; Kidney; Kidne

1964
LIVER AND KIDNEY DAMAGE AFTER ANESTHESIA.
    Southern medical journal, 1965, Volume: 58

    Topics: Anesthesia; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Child; Ether; Halothane;

1965
Untoward side effects and toxicities of inhalational anesthetics.
    Middle East journal of anaesthesiology, 1984, Volume: 7, Issue:4

    Topics: Anesthesia, Inhalation; Anesthetics; Carcinogens; Chemical and Drug Induced Liver Injury; Enflurane;

1984
Anesthetic pollution and disease.
    Journal of the American Veterinary Medical Association, 1980, Mar-15, Volume: 176, Issue:6

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Air Pollutants, Occupational; Anesthesiology; An

1980
Halothane-induced nephrotoxicity.
    Urology, 1981, Volume: 17, Issue:4

    Topics: Aged; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Female; Halothane; Humans; Kid

1981
Toxic metabolites from biotransformation: major organ damage.
    International anesthesiology clinics, 1981,Winter, Volume: 19, Issue:4

    Topics: Anesthetics; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Enflurane; Ether; H

1981
Study relates health problems to anesthetic gases...
    American Industrial Hygiene Association journal, 1980, Volume: 41, Issue:1

    Topics: Abortion, Spontaneous; Adult; Anesthesia, Dental; Anesthesia, Inhalation; Chemical and Drug Induced

1980
The liver and halothane-again.
    British medical journal, 1980, Jun-28, Volume: 280, Issue:6231

    Topics: Chemical and Drug Induced Liver Injury; Enflurane; Halothane; Humans; Kidney Diseases; Microsomes, L

1980
Renal function in Fischer 344 rats with chronic renal impairment after administration of enflurane and gentamicin.
    Anesthesiology, 1980, Volume: 53, Issue:6

    Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Body Weight; Chronic Disease; Creatinine; Enflura

1980
Quantitative differences in the production and toxicity of CF2=BrCl versus CH2F-O-C(=CF2)(CF3) (compound A): the safety of halothane does not indicate the safety of sevoflurane.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:5

    Topics: Absorption; Aminooxyacetic Acid; Anesthetics, Inhalation; Animals; Chemical Phenomena; Chemistry, Ph

1997
Editorial: "Old lamps for new".
    British journal of anaesthesia, 1975, Volume: 47, Issue:8

    Topics: Anesthesia, Inhalation; Arrhythmias, Cardiac; Enflurane; Ethers; Halothane; Humans; Isoflurane; Kidn

1975
RNA-synthesis in rat kidneys after fluorinated anesthetics or inorganic fluoride administration.
    Experientia, 1979, Jan-15, Volume: 35, Issue:1

    Topics: Animals; Depression, Chemical; Enflurane; Fluorides; Halothane; Kidney; Kidney Diseases; Male; Metho

1979
Renal effects of enflurane anesthesia in Fischer 344 rats with pre-existing renal insufficiency.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 211, Issue:1

    Topics: Animals; Enflurane; Fluorides; Halothane; Kidney; Kidney Diseases; Male; Rats; Rats, Inbred F344; Ti

1979
Effect of enzyme induction on nephrotoxicity of halothane-related compounds.
    Environmental health perspectives, 1977, Volume: 21

    Topics: Anesthetics; Animals; Biotransformation; Enflurane; Environmental Exposure; Enzyme Induction; Fluori

1977
Pathologic changes following chronic exposures to halothane: a review.
    Environmental health perspectives, 1977, Volume: 21

    Topics: Animals; Brain; Brain Diseases; Chemical and Drug Induced Liver Injury; Dogs; Environmental Exposure

1977
[Adverse effects of modern inhalation anesthetics. 2. Control of amounts and elimination of escaping anesthesia gases].
    Fortschritte der Medizin, 1978, Dec-14, Volume: 96, Issue:47-48

    Topics: Air Conditioning; Air Pollutants; Air Pollutants, Occupational; Anesthetics; Chemical and Drug Induc

1978
Drug therapy. Drug allergy (second of three parts).
    The New England journal of medicine, 1975, Apr-03, Volume: 292, Issue:14

    Topics: Allergens; Anaphylaxis; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Drug Hypers

1975
Medical risks and dental anaesthetics.
    The Practitioner, 1975, Volume: 214, Issue:1281

    Topics: Analgesics; Anesthesia, Dental; Anesthesia, General; Anesthesia, Local; Anti-Bacterial Agents; Antic

1975
Ultrastructural studies on the pathological change in the neonatal kidney following in utero exposure to halothane.
    Environmental research, 1975, Volume: 10, Issue:2

    Topics: Air Pollutants, Occupational; Animals; Female; Halothane; Humans; Kidney; Kidney Diseases; Kidney Tu

1975
Detection of cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts.
    The Journal of biological chemistry, 1991, Oct-05, Volume: 266, Issue:28

    Topics: Acetamides; Animals; Cross Reactions; Cysteine; Enzyme-Linked Immunosorbent Assay; Fluoroacetates; H

1991
Comparison of anesthetic techniques in patients undergoing heart valve replacement.
    Journal of cardiothoracic anesthesia, 1990, Volume: 4, Issue:2

    Topics: Analysis of Variance; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Cardiopulmonary

1990
Increased toxicity of the antitumor drug cyclophosphamide in mice in the presence of the volatile anesthetic agent halothane.
    Cancer chemotherapy and pharmacology, 1986, Volume: 16, Issue:1

    Topics: Animals; Brain; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Dose-Resp

1986
Hepatic and renal effects of prolonged exposure of rats to 50 p.p.m. methoxyflurane.
    Acta pharmacologica et toxicologica, 1985, Volume: 57, Issue:3

    Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Fatty Liver; Fluorides; Halothane; Kid

1985
The changing pattern of childhood.
    Postgraduate medicine, 1971, Volume: 49, Issue:2

    Topics: Acidosis; Adipose Tissue; Alpha-Globulins; Anemia, Aplastic; Biliary Tract Diseases; Brain Diseases;

1971
Hazards of gallamine administration in patients with renal failure.
    The Journal of urology, 1972, Volume: 108, Issue:4

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Inhalation; Blood Urea Nitrogen; Duodenal Ulcer; Female; G

1972
Frequency and type of renal and electrolyte disorders in fulminant hepatic failure.
    British medical journal, 1974, Feb-02, Volume: 1, Issue:5900

    Topics: Acetaminophen; Acute Kidney Injury; Blood Glucose; Chemical and Drug Induced Liver Injury; Creatinin

1974
The syndrome of methoxyflurane-associated hepatitis.
    Annals of internal medicine, 1974, Volume: 80, Issue:3

    Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Drug Hypersensitivity;

1974
Changes in serum uric acid related to the dose of methoxyflurane.
    British journal of anaesthesia, 1974, Volume: 46, Issue:1

    Topics: Anesthesia, General; Dose-Response Relationship, Drug; Fluorides; Halothane; Humans; Kidney Diseases

1974
Changes in urine osmolality and urine fluoride concentrations following methoxyflurane anaesthesia.
    British journal of anaesthesia, 1974, Volume: 46, Issue:2

    Topics: Anesthesia, General; Dose-Response Relationship, Drug; Fluorides; Halothane; Humans; Kidney Diseases

1974
Renal effects of low-dose methoxyflurane with cardiopulmonary bypass.
    Anesthesiology, 1972, Volume: 36, Issue:3

    Topics: Adjuvants, Anesthesia; Anesthesia, General; Blood Urea Nitrogen; Creatinine; Extracorporeal Circulat

1972
Drugs containing halogen atoms: toxicity and lack of toxicity.
    Journal of the Medical Association of Georgia, 1972, Volume: 61, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Ethers; Halothane; Heart Diseases; Humans; Hydrocarbons, Hal

1972
Fluorine compounds in biological materials.
    Ciba Foundation symposium, 1971, Volume: 2

    Topics: Blood Proteins; Chromatography; Electrophoresis, Paper; Fluorine; Halothane; Humans; Kidney Diseases

1971
[Effects of halogenated anesthetics on the liver, thyroid gland and kidney].
    L'union medicale du Canada, 1970, Volume: 99, Issue:4

    Topics: Adolescent; Chemical and Drug Induced Liver Injury; Halothane; Humans; Kidney; Kidney Diseases; Live

1970
[Clinical evaluation of "Anestezist 1" universal vaporizer].
    Novosti meditsinskogo priborostroeniia, 1970, Volume: 2

    Topics: Adult; Aged; Anesthesia, Inhalation; Chloroform; Electroencephalography; Ethyl Ethers; Evaluation St

1970
Halothane anesthesia following methoxyflurane-induced nephrotoxicity.
    Anesthesiology, 1970, Volume: 33, Issue:4

    Topics: Anesthesia, Inhalation; Castration; Diabetes Insipidus; Female; Halothane; Humans; Hysterectomy; Kid

1970
Renal ischemia and anesthesia.
    Southern medical journal, 1971, Volume: 64, Issue:8

    Topics: Anesthesia, Inhalation; Animals; Blood Urea Nitrogen; Ethyl Ethers; Halothane; Ischemia; Kidney; Kid

1971
Massive hepatic necrosis following multiple exposures to halothane.
    The American journal of medicine, 1968, Volume: 45, Issue:4

    Topics: Aged; Brain; Diagnosis, Differential; Female; Halothane; Hemorrhage; Humans; Kidney; Kidney Diseases

1968
[Clinical uses of the hypotensive action of fluothane].
    Minerva chirurgica, 1969, Apr-13, Volume: 24, Issue:7

    Topics: Angiography; Cerebrovascular Disorders; Coronary Disease; Halothane; Humans; Hypotension, Controlled

1969