Page last updated: 2024-10-28

halothane and Infarction, Middle Cerebral Artery

halothane has been researched along with Infarction, Middle Cerebral Artery in 6 studies

Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.

Research Excerpts

ExcerptRelevanceReference
"Cerebral blood flow (CBF) and blood-brain barrier (BBB) permeability by arterial spin labeling (ASL)- and dynamic contrast enhanced (DCE)-magnetic resonance imaging (MRI), respectively were repeatedly measured under either halothane (N  =  5) or isoflurane (N  =  5) anesthesia in a rat stroke model of embolic occlusion of middle cerebral artery (MCA)."7.80Rate and extent of leakage of a magnetic resonance contrast agent tend to be lower under isoflurane anesthesia in comparison to halothane in a rat model of embolic stroke. ( Alarcon, W; Bezerra, FJ; Brown, M; Karki, K; Keenan, KA; Knight, RA; Nagaraja, TN, 2014)
"Cerebral blood flow (CBF) and blood-brain barrier (BBB) permeability by arterial spin labeling (ASL)- and dynamic contrast enhanced (DCE)-magnetic resonance imaging (MRI), respectively were repeatedly measured under either halothane (N  =  5) or isoflurane (N  =  5) anesthesia in a rat stroke model of embolic occlusion of middle cerebral artery (MCA)."3.80Rate and extent of leakage of a magnetic resonance contrast agent tend to be lower under isoflurane anesthesia in comparison to halothane in a rat model of embolic stroke. ( Alarcon, W; Bezerra, FJ; Brown, M; Karki, K; Keenan, KA; Knight, RA; Nagaraja, TN, 2014)
"Using an IPC of 2 5-minute MCAO episodes, the reduction in infarct volume from the test MCAO was maximal with a 72-hour delay in striatum (70%) and cerebral cortex (64%) when halothane was used for surgical anesthesia."3.74Delayed tolerance with repetitive transient focal ischemic preconditioning in the mouse. ( Huang, J; Klaus, JA; Koehler, RC; Yang, ZJ; Zhang, J, 2008)
"Halothane-pretreated animals were subjected to MCAO 24 hours after AP."1.31Tolerance against ischemic neuronal injury can be induced by volatile anesthetics and is inducible NO synthase dependent. ( Dirnagl, U; Fütterer, C; Isaev, NK; Kapinya, KJ; Löwl, D; Maurer, M; Waschke, KF, 2002)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Keshavarz, S1
Nemati, M1
Saied Salehi, M1
Naseh, M1
Chen, G1
Kamat, PK1
Ahmad, AS1
Doré, S1
Bezerra, FJ1
Brown, M1
Alarcon, W1
Karki, K1
Knight, RA1
Keenan, KA1
Nagaraja, TN1
Zhang, J1
Yang, ZJ1
Klaus, JA1
Koehler, RC1
Huang, J1
Bhardwaj, A1
Castro III, AF1
Alkayed, NJ1
Hurn, PD1
Kirsch, JR1
Kapinya, KJ1
Löwl, D1
Fütterer, C1
Maurer, M1
Waschke, KF1
Isaev, NK1
Dirnagl, U1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Inhalatorial Sedation in Patient With SAH Versus Conventional Intravenous Sedation (GAS-SAH)[NCT00830843]Phase 413 participants (Actual)Interventional2009-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

6 other studies available for halothane and Infarction, Middle Cerebral Artery

ArticleYear
The impact of anesthetic drugs on hemodynamic parameters and neurological outcomes following temporal middle cerebral artery occlusion in rats.
    Neuroreport, 2023, 03-01, Volume: 34, Issue:4

    Topics: Anesthetics; Animals; Brain Ischemia; Chloral Hydrate; Halothane; Hemodynamics; Infarction, Middle C

2023
Distinctive effect of anesthetics on the effect of limb remote ischemic postconditioning following ischemic stroke.
    PloS one, 2020, Volume: 15, Issue:1

    Topics: Analgesics; Anesthetics; Animals; Brain Infarction; Brain Ischemia; Extremities; Halothane; Infarcti

2020
Rate and extent of leakage of a magnetic resonance contrast agent tend to be lower under isoflurane anesthesia in comparison to halothane in a rat model of embolic stroke.
    Neurological research, 2014, Volume: 36, Issue:9

    Topics: Anesthetics, Inhalation; Animals; Blood-Brain Barrier; Brain Ischemia; Cerebrovascular Circulation;

2014
Delayed tolerance with repetitive transient focal ischemic preconditioning in the mouse.
    Stroke, 2008, Volume: 39, Issue:3

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Brain; Cell Survival; Cerebral Cortex; Corpus Striatum

2008
Anesthetic choice of halothane versus propofol: impact on experimental perioperative stroke.
    Stroke, 2001, Volume: 32, Issue:8

    Topics: Administration, Inhalation; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intrav

2001
Tolerance against ischemic neuronal injury can be induced by volatile anesthetics and is inducible NO synthase dependent.
    Stroke, 2002, Volume: 33, Issue:7

    Topics: Anesthetics, Inhalation; Animals; Body Temperature; Brain; Brain Infarction; Brain Ischemia; Cells,

2002