Page last updated: 2024-10-28

halothane and Diathesis

halothane has been researched along with Diathesis in 147 studies

Research Excerpts

ExcerptRelevanceReference
"The most commonly used laboratory test for predicting malignant hyperthermia susceptibility is the caffeine halothane contracture test."9.07Prediction of malignant hyperthermia susceptibility in low-risk subjects. An epidemiologic investigation of caffeine halothane contracture responses. The North American Malignant Hyperthermia Registry. ( Bunn, JS; Diaz, M; Landis, JR; Larach, MG, 1992)
" We evaluated whether toxic concentrations of cocaine altered the in vitro muscle response to halothane during contracture tests for MH."7.69Effect of cocaine on the contracture response to 1% halothane in patients undergoing diagnostic muscle biopsy for malignant hyperthermia. ( Brum, JM; DeBoer, GE; Mitsumoto, H; Sato, N, 1995)
"The in vitro halothane and caffeine contracture tests have been performed on muscle tissue from six survivors of the neuroleptic malignant syndrome."7.67Neuroleptic malignant syndrome and malignant hyperthermia. In vitro comparison with halothane and caffeine contracture tests. ( Adnet, P; Guevart, E; Krivosic-Horber, R; Lestavel, P; Theunynck, D, 1987)
" The literature is briefly reviewed and an account of the present status of malignant hyperthermia (porcine stress syndrome) in Ontario boars using the halothane or halothane/succinylcholine screening tests is presented."7.66Halothane and halothane/succinylcholine induced malignant hyperthermia (porcine stress syndrome) in a population of Ontario boars. ( Basrur, PK; McDonell, WN; Seeler, DC, 1983)
"The most commonly used laboratory test for predicting malignant hyperthermia susceptibility is the caffeine halothane contracture test."5.07Prediction of malignant hyperthermia susceptibility in low-risk subjects. An epidemiologic investigation of caffeine halothane contracture responses. The North American Malignant Hyperthermia Registry. ( Bunn, JS; Diaz, M; Landis, JR; Larach, MG, 1992)
" However, experts worldwide agree that the only reference test to this day remains the in vitro halothane caffeine contracture tests."4.77[Screening tests for malignant hyperthermia susceptibility]. ( Adnet, P; Krivosic-Horber, R, 1989)
" Diagnosis is based on in vitro muscle contracture in response to halothane and/or caffeine exposure."3.70[Malignant hyperthermia susceptibility in 3 patients with malignant neuroleptic syndrome]. ( Bahia, VS; Marchiori, PE; Oliveira, RA; Scaff, M; Silva, HC; Tsanaclis, AM, 2000)
" We evaluated whether toxic concentrations of cocaine altered the in vitro muscle response to halothane during contracture tests for MH."3.69Effect of cocaine on the contracture response to 1% halothane in patients undergoing diagnostic muscle biopsy for malignant hyperthermia. ( Brum, JM; DeBoer, GE; Mitsumoto, H; Sato, N, 1995)
" The halothane/caffeine contracture test was performed on the biopsied muscle."3.69Incidence of malignant hyperthermia reactions in 2,214 patients undergoing muscle biopsy. ( Britt, BA; Carr, AS; Cunliffe, M; Lerman, J; McLeod, ME, 1995)
"The early effects of 5 or 10 min global cerebral ischemia, sham operation and halothane anesthesia were evaluated in Mongolian gerbils by means of electroencephalography (EEG), neurological examination and passive avoidance training."3.69Response variability to ischemic injury in the Mongolian gerbil: an electroencephalographic and behavioral study. ( Adami, M; Ambrosini, MV; Bruschelli, G; de Rino, F; Gambelunghe, C; Mariucci, G, 1996)
"The in vitro contracture test determines the sensitivity of freshly obtained skeletal muscle specimens to caffeine or halothane applied to a bathing solution."3.68In vitro contracture testing for determination of susceptibility to malignant hyperthermia: a methodologic update. ( Gallagher, WJ; Iaizzo, PA; Wedel, DJ, 1991)
" In vitro, human MHS muscle samples were exposed to propofol and changes in (a) baseline tension and (b) contracture tension on exposure to halothane and caffeine were measured."3.68Propofol is a 'safe' anaesthetic agent in malignant hyperthermia susceptible patients. ( Couchman, KG; McKenzie, AJ; Pollock, N, 1992)
"The in vitro halothane and caffeine contracture tests have been performed on muscle tissue from six survivors of the neuroleptic malignant syndrome."3.67Neuroleptic malignant syndrome and malignant hyperthermia. In vitro comparison with halothane and caffeine contracture tests. ( Adnet, P; Guevart, E; Krivosic-Horber, R; Lestavel, P; Theunynck, D, 1987)
" Halothane-caffeine contracture tests, interpreted in accordance with the criteria of the European Group on Malignant Hyperthermia, yielded the following results: 13 positive (MHS), 10 negative (MHN), 4 equivocal (MHE)."3.67[Tests of contracture and sensitivity to malignant hyperthermia in 27 patients]. ( Adamantidis, M; Adnet, P; Guévart, E; Krivosic, I; Krivosic-Horber, R; Theunynck, D, 1988)
" The in vitro halothane-caffeine contracture tests are the most reliable method of identifying individuals susceptible to MH."3.67The association between the neuroleptic malignant syndrome and malignant hyperthermia. ( Adamantidis, MM; Adnet, PJ; Adnet-Bonte, CA; Dupuis, BA; Haudecoeur, G; Krivosic-Horber, RM; Saulnier, F, 1989)
" The literature is briefly reviewed and an account of the present status of malignant hyperthermia (porcine stress syndrome) in Ontario boars using the halothane or halothane/succinylcholine screening tests is presented."3.66Halothane and halothane/succinylcholine induced malignant hyperthermia (porcine stress syndrome) in a population of Ontario boars. ( Basrur, PK; McDonell, WN; Seeler, DC, 1983)
"Masseter spasm is often associated with severe rhabdomyolysis in patients with muscle dystrophy, especially Duchenne's dystrophy."2.38[Clinical features of malignant hyperthermia crisis]. ( Cornet, C; Laxenaire, MC; Moeller, R, 1989)
"Patients with malignant hyperthermia susceptibility were classified into subgroups HH and HS (positive to halothane only and positive to both caffeine and halothane)."1.91Distinct pathophysiological characteristics in developing muscle from patients susceptible to malignant hyperthermia. ( Figueroa, L; Ibarra-Moreno, CA; Kraeva, N; Manno, C; Riazi, S; Rios, E; Tammineni, ER, 2023)
"The variable clinical presentation of malignant hyperthermia (MH), a disorder of calcium signalling, hinders its diagnosis and management."1.51Abnormal calcium signalling and the caffeine-halothane contracture test. ( Figueroa, L; Kraeva, N; Manno, C; Riazi, S; Ríos, E; Toro, S, 2019)
"Sevoflurane is a known triggering agent of malignant hyperthermia (MH)."1.39Sevoflurane is less sensitive than halothane for in vitro detection of malignant hyperthermia susceptibility. ( Heiderich, S; Johannsen, S; Klingler, W; Roewer, N; Schneiderbanger, D; Schuster, F, 2013)
"To diagnose malignant hyperthermia (MH) susceptibility, muscle bundles are exposed to halothane and caffeine."1.37Sevoflurane as a potential replacement for halothane in diagnostic testing for malignant hyperthermia susceptibility: results of a preliminary study. ( Anetseder, M; Hartung, E; Metterlein, T; Roewer, N; Schuster, F, 2011)
"In vitro contracture testing to diagnose malignant hyperthermia (MH) susceptibility requires a muscle biopsy, which may be associated with severe side effects for the patient."1.35An in-vivo metabolic test for detecting malignant hyperthermia susceptibility in humans: a pilot study. ( Anetseder, M; Kranke, P; Metterlein, T; Muellenbach, RM; Negele, S; Roewer, N; Schuster, F; Schwemmer, U, 2008)
" MH susceptibility leads to a leftward shift of the dose-response curve for IM lactate after local injection of halothane and caffeine."1.33The dose-response relationship and regional distribution of lactate after intramuscular injection of halothane and caffeine in malignant hyperthermia-susceptible pigs. ( Anetseder, M; Hager, M; Müller, R; Roewer, N; Schöll, H; Schuster, F, 2006)
"The effect was most pronounced in seizure-prone animals, and subsequent to anaesthetic-induced behavioural immobility, these animals also showed a regional resistance to the depression of spontaneous slow potential shift oscillations."1.30Large slow potential shifts occur during halothane anaesthesia in gerbils. ( Laming, PR; Roughan, JV, 1998)
"The phenotype of susceptibility to malignant hyperthermia (MHS); can only be detected reliably by the in vitro caffeine-halothane contracture test (CHCT)."1.30[Effect of chlorocresol vs caffeine on muscle contracture in malignant hyperthermia susceptible patients]. ( Adnet, PJ; Ben-Abraham, R; Haudcoeur, G; Krivosic-Horber, RM; Perel, A, 1997)
" MHEh muscles revealed a dose-response curve similar to that found in MHN specimens."1.30Classification of malignant hyperthermia-equivocal patients by 4-chloro-M-cresol. ( Bittner, RE; Fricker, R; Gilly, H; Kress, HG; Musat, I; Steinbereithner, K, 1997)
"The association between malignant hyperthermia (MH) and neuromuscular disorders is controversial."1.30Dystrophin deficient mdx muscle is not prone to MH susceptibility: an in vitro study. ( Bittner, RE; Gilly, H; Mader, N, 1997)
"To investigate a possible link of malignant hyperthermia to capture myopathy, between June 1990 and July 1993 we anesthetized four black-tailed deer (Odocoileus hemionus columbianus) and challenged them with halothane and succinylcholine."1.29Evaluation for malignant hyperthermia susceptibility in black-tailed deer. ( Antognini, JF; Eisele, PH; Gronert, GA, 1996)
"Isoflurane has a lesser ability than halothane to induce contracture in malignant hyperthermia (MH) muscle in vitro."1.28Effect of Bay K 8644 on the magnitude of isoflurane and halothane contracture of skeletal muscle from patients susceptible to malignant hyperthermia. ( Adamantidis, MM; Adnet, PJ; Haudecoeur, G; Imbenotte, M; Krivosic-Horber, RM; Reyford, H, 1992)
"Pre-treatment with ryanodine did not change the calcium signal brought about by halothane or ionomycin."1.28[Effects of halothane, caffeine and ryanodine on the intracellular calcium store in blood mononuclear cells]. ( Endo, M; Iino, M; Kawana, Y; Oyamada, H, 1992)
"The mechanisms causing the malignant hyperthermia (MH) syndrome are related to a malfunction of intracellular Ca2+ homeostasis and can be prevented or reversed by dantrolene."1.28EU 4093 decreases intracellular [Ca2+] in skeletal muscle fibers from control and malignant hyperthermia-susceptible swine. ( Allen, PD; López, JR; Ryan, JF; Sánchez, V; Sreter, FA, 1992)
"In vitro muscle contracture tests for malignant hyperthermia screening are routinely performed using standardized protocols."1.28Effect of halothane equilibration kinetics on in vitro muscle contractures for malignant hyperthermia screening. ( Censier, K; Drewe, J; Funk, B; Urwyler, A, 1992)
"Halothane was dosed by chromatography in the three compartments of a bath for isolated organs with a muscular fiber during steady concentrations were given and after wash out."1.28[Malignant hyperthermia: halothane kinetics in a study model of muscular contraction. Head space determination and comparison with a mathematical model]. ( Guevart, E; Haguenoer, JM; Imbenotte, M; Theunynck, D, 1991)
" In six MH(-) patients with previous masseter muscle rigidity, no adverse reactions occurred in response to volatile anesthetic agents."1.28Safety of general anesthesia in patients previously tested negative for malignant hyperthermia susceptibility. ( Allen, GC; Fletcher, JE; Rosenberg, H, 1990)
" In contrast, propranolol shifted the caffeine dose-response curve to the right and significantly increased the caffeine threshold in the MHS group."1.28Influence of propranolol on the in vitro response to caffeine and halothane in malignant hyperthermia-susceptible muscle. ( Ording, H, 1989)
"in an attempt to induce malignant hyperthermia."1.27Failure to induce malignant hyperthermia in myotonic goats. ( Gronert, GA; Lambert, EH; Newberg, LA, 1983)
"Malignant hyperthermia is a potentially lethal syndrome that can be triggered by inhaled anesthetics."1.27Preparation of anesthesia machines for patients susceptible to malignant hyperthermia. ( Beebe, JJ; Sessler, DI, 1988)
"Malignant hyperthermia is a seemingly rare genetic myopathy."1.27Malignant hyperthermia in plastic surgery. ( Abdul-Rasool, IH; Dubrow, TJ; Lesavoy, MA; Wackym, PA, 1988)
"A European Malignant Hyperpyrexia Group has been formed to facilitate exchange of information between centres performing in vitro muscle testing for malignant hyperpyrexia susceptibility."1.27A protocol for the investigation of malignant hyperpyrexia (MH) susceptibility. The European Malignant Hyperpyrexia Group. ( , 1984)
"The caffeine test was positive in 68% of MHS patients, 0."1.27Investigation of malignant hyperthermia in Denmark and Sweden. ( Fletcher, R; Ording, H; Ranklev, E, 1984)
"The relationship between neuroleptic malignant syndrome (NMS) and malignant hyperthermia (MH) was investigated using the in vitro skeletal muscle contracture test to screen for MH-susceptibility in NMS patients."1.27Malignant hyperthermia susceptibility in neuroleptic malignant syndrome. ( Caroff, SN; Fletcher, JE; Heiman-Patterson, TD; Mann, SC; Rosenberg, H, 1987)
"In vitro tests for the diagnosis of malignant hyperthermia susceptibility were performed in 105 patients and 20 normal controls according to the protocol of the European MH Group."1.27In vitro diagnosis of susceptibility to malignant hyperthermia: comparison between dynamic and static halothane and caffeine tests. ( Ording, H; Skovgaard, LT, 1987)
"The familial nature of anaesthetic malignant hyperthermia must lead to the search for susceptibility in other members of the family of a sensitive subject."1.27[Examination of the family of a patient susceptible to anesthetic malignant hyperthermia]. ( Adnet, P; Guévart, E; Krivosic, I; Krivosic-Horber, R; Theunynck, D, 1986)
"The father was found to be malignant hyperpyrexia-susceptible."1.27Malignant hyperpyrexia and sudden death. ( Fletcher, R; Krantz, P; Ranklev, E, 1985)

Research

Studies (147)

TimeframeStudies, this research(%)All Research%
pre-199050 (34.01)18.7374
1990's78 (53.06)18.2507
2000's12 (8.16)29.6817
2010's5 (3.40)24.3611
2020's2 (1.36)2.80

Authors

AuthorsStudies
Carlson, KJ1
Sun, SA1
Swan, C1
Koenig, M1
Derkay, CS1
Figueroa, L2
Kraeva, N3
Manno, C2
Ibarra-Moreno, CA1
Tammineni, ER1
Riazi, S3
Rios, E2
Thompson, SJ1
Noseworthy, MD1
Rayner, TE1
Schneiderman, JE1
Cifra, B1
Wells, GD1
Toro, S1
Johannsen, S1
Klingler, W2
Schneiderbanger, D1
Heiderich, S1
Roewer, N10
Schuster, F5
Sagui, E1
Montigon, C1
Abriat, A1
Jouvion, A1
Duron-Martinaud, S1
Canini, F2
Zagnoli, F1
Bendahan, D2
Figarella-Branger, D1
Brégigeon, M1
Brosset, C1
Metterlein, T3
Negele, S1
Kranke, P2
Muellenbach, RM1
Schwemmer, U1
Anetseder, M5
Hartung, E3
Snoeck, MM1
Oosterhof, A1
Tangerman, A1
Veerkamp, JH2
van Engelen, BG1
Gielen, MJ1
Islander, G1
Ording, H10
Bendixen, D2
Ranklev Twetman, E1
Allen, PD3
López, JR3
Sei, Y1
Brandom, BW1
Bina, S2
Hosoi, E1
Gallagher, KL1
Wyre, HW1
Pudimat, PA1
Holman, SJ1
Venzon, DJ1
Daly, JW1
Muldoon, S2
Wappler, F5
Baur, CP1
Censier, K3
Doetsch, S1
Felleiter, P1
Fiege, M2
Fricker, R2
Halsall, PJ6
Heffron, JJ1
Heytens, L2
Hopkins, PM5
Lehmann-Horn, F5
Nivoche, Y1
Tegazzin, V1
Tzanova, I1
Urwyler, A4
Weisshorn, R1
Schulte am Esch, J5
Litman, RS1
Rosenberg, H15
Schöll, H1
Hager, M1
Müller, R1
Bünger, R1
Gardill, A1
de Roose, P1
Pauwels, H1
Lampo, P1
Oyaert, W1
van den Hende, C1
Ranklev, E4
Fletcher, R4
Seeler, DC1
McDonell, WN2
Basrur, PK2
Gerrard, JM1
Duncan, PG1
Koshyk, SA1
Glover, SM1
McCrea, JM1
Newberg, LA1
Lambert, EH1
Gronert, GA4
Reed, S1
Nelson, TE3
Flewellen, EH1
Gloyna, DF1
Dantzer, R1
Hatey, F1
Tonner, PH1
Scholz, J4
Richter, A1
Löscher, W1
Steinfath, M3
Wlaz, P1
Hadji, B1
Singh, S2
Becker, K1
Lenzen, C1
Köchling, A2
Sato, N1
Brum, JM1
Mitsumoto, H1
DeBoer, GE1
Bello, N1
Adnet, P6
Saulnier, F2
Lestavel, P2
Adnet-Bonte, C1
Reyford, H3
Etchrivi, T1
Tavernier, B2
Krivosic-Horber, R6
Deufel, T1
Sudbrak, R1
Feist, Y1
Rübsam, B1
Du Chesne, I1
Schäfer, KL1
Grimm, T1
Hartung, EJ1
Carr, AS1
Lerman, J1
Cunliffe, M1
McLeod, ME1
Britt, BA2
Ducart, A1
Renaud, B1
Riou, B1
O'Flynn, RP1
Shutack, JG1
Fletcher, JE11
Kaufmann, MA1
Drewe, J2
Adnet, PJ9
Krivosic-Horber, RM9
Krivosic, I3
Haudecoeur, G8
Reyford, HG2
Adamantidis, MM7
Medahoui, H1
Mortier, W1
Breucking, E1
Rempel, WE4
Lu, M1
el Kandelgy, S1
Kennedy, CF1
Irvin, LR1
Mickelson, JR2
Louis, CF3
Calvo, PA1
Payen, JF2
Bosson, JL2
Bourdon, L2
Jacquot, C1
Le Bas, JF1
Stieglitz, P2
Benabid, AL1
Ellis, FR5
Wedel, DJ4
Gammel, SA1
Milde, JH1
Iaizzo, PA6
Serfas, KD1
Bose, D1
Patel, L1
Wrogemann, K1
Phillips, MS1
MacLennan, DH1
Greenberg, CR1
Wieland, SJ2
Gong, QH2
Gambelunghe, C1
Mariucci, G1
Bruschelli, G1
Adami, M1
de Rino, F1
Ambrosini, MV1
Sessler, DI2
Neubert, E1
Gürtler, H1
Vallentin, G1
Kozak-Ribbens, G1
Confort-Gouny, S1
Cozzone, PJ1
Stewart, AD1
Weglinski, MR1
Engel, AG1
Gilly, H2
Musat, I1
Bittner, RE2
Steinbereithner, K3
Kress, HG1
Bachand, M1
Vachon, N1
Boisvert, M1
Mayer, FM1
Chartrand, D1
Ben-Abraham, R1
Haudcoeur, G1
Perel, A1
Mader, N1
Glahn, K1
Gardi, T1
Fagerlund, T1
Antognini, JF1
Eisele, PH2
Mezin, P1
Brambilla, E1
Ummenhofer, W1
Roesslein, R1
Sutter, PM1
Moser, N1
Kern, C1
Winkler, G1
Schulte am Esch, JS1
Roughan, JV1
Laming, PR1
Goresky, GV1
Cox, RG1
Hawkes, CA1
Etchrivi, TS1
Diallo, A1
Silva, HC1
Bahia, VS1
Oliveira, RA1
Marchiori, PE1
Scaff, M1
Tsanaclis, AM1
Agarwal, K1
Matschke, J1
Schulte Am Esch , J1
Knowles, PF1
Imbenotte, M3
Cosgrove, SB1
Martucci, RW2
Peluso, A1
Bianchini, A1
Funk, B1
McKenzie, AJ1
Couchman, KG1
Pollock, N1
Kawana, Y1
Iino, M1
Oyamada, H1
Endo, M1
Zualkernan, K1
Roghair, T1
Reyford, GH1
Cordonnier, C2
Sánchez, V2
Ryan, JF2
Sreter, FA2
Larach, MG2
Landis, JR1
Bunn, JS1
Diaz, M1
Martin, JJ1
Van de Kelft, E1
Bossaert, LL1
Olthoff, D1
Meinecke, CD1
Preis, I1
Engelhardt, W1
Krauspe, R1
Poels, PJ1
Joosten, EM1
Sengers, RC1
Stadhouders, AM1
Benders, AA1
Slogoff, S1
Keats, AS1
Dear, WE1
Abadia, A1
Lawyer, JT1
Moulds, JP1
Williams, TM1
Gallagher, WJ1
Rum, U1
Schmitz, W1
Scholz, H1
Seewald, MJ2
Eichinger, HM2
Theunynck, D4
Guevart, E4
Haguenoer, JM1
Jaffe, RS1
Elliott, TE1
Cardinet, GH1
Conti, PA2
Olgin, J1
Allen, G1
Seestedt, R1
Chance, B1
Olsen, R1
Chapman, DE1
Berggren, M1
Powis, G1
Klip, A1
Mills, GB1
Elliott, ME1
Kochs, E1
Hoffman, WE1
Allen, GC2
Huggins, FJ1
Reyfort, GH1
Dupuis, BA3
Foder, B1
Scharff, O1
Lopez, I1
Mendoza, M1
O'Brien, PJ3
Kalow, BI2
Ali, N1
Lassaline, LA1
Lumsden, JH2
Cornet, C1
Moeller, R1
Laxenaire, MC1
Adnet-Bonte, CA1
Foster, PS1
Hopkinson, KC1
Denborough, MA1
Hackl, W2
Winkler, M1
Mauritz, W2
Burket, RC1
Hodgin, JD1
Ohnishi, ST1
Katagi, H1
Ohnishi, T1
Brownell, AK1
Brown, BD1
Jacobs, RM1
Beebe, JJ1
Wackym, PA1
Dubrow, TJ1
Abdul-Rasool, IH1
Lesavoy, MA1
Adamantidis, M1
Duthie, GG1
Arthur, JR1
Simpson, SP1
Nicol, F1
Klein, W1
Sporn, P1
Graf, M1
Sluga, E1
Gallant, EM2
Bouvet, A1
Yamashiro, S1
Caroff, SN1
Heiman-Patterson, TD1
Mann, SC1
Tolpin, EI1
Michaux, K1
Skovgaard, LT2
Blomquist, S1
Lunam, CA1
Cousins, MJ1
Hall, PM1
Otsuka, S1
Yamamoto, M1
Kasuya, S1
Ohtomo, H1
Yamamoto, Y1
Yoshida, TO1
Akaza, T1
Fletcher, TF1
Goettl, VM1
Krantz, P1
Rooney, MT1
Reik, TR1
Thatte, HS1
Addis, PB1
Monti, M1
Ilias, WK1
Williams, CH1
Fulfer, RT1
Dozier, SE1
Farrell, G1
Prendergast, D1
Murray, M1
Fishbein, WN1
Muldoon, SM1
Deuster, PA1
Armbrustmacher, VW1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Freeman-Sheldon Syndrome Evaluation and Diagnosis in Clinical Settings (FSS-EDICT) I: a Case-Control, Cross-Sectional Study of Baseline and Stress Physiology Parameters[NCT01306994]0 participants (Actual)Observational2014-03-31Withdrawn (stopped due to Lack of patient interest)
Implication of Patient in the Making Ready of Recommendations for the Antivitamin K's Gestion in Case of Thrombosis Embolic Venous's Illness. Randomised Study for Clinical Validation.[NCT00227097]300 participants Observational2002-12-31Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for halothane and Diathesis

ArticleYear
[Clinical features of malignant hyperthermia crisis].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:5

    Topics: Adolescent; Adult; Anesthesia, General; Arrhythmias, Cardiac; Carbon Dioxide; Child; Child, Preschoo

1989
[Screening tests for malignant hyperthermia susceptibility].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:5

    Topics: Animals; Caffeine; Calcium; Cholinesterases; Contracture; Creatine Kinase; Cyclic AMP; Disease Susce

1989
Standardization of the caffeine halothane muscle contracture test. North American Malignant Hyperthermia Group.
    Anesthesia and analgesia, 1989, Volume: 69, Issue:4

    Topics: Biopsy; Caffeine; Clinical Laboratory Techniques; Disease Susceptibility; Halothane; Humans; Maligna

1989
Pathophysiology of malignant hyperthermia.
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:5

    Topics: Animals; Calcium; Creatine Kinase; Dantrolene; Disease Susceptibility; Halothane; Humans; Lymphocyte

1989
Diagnosis of susceptibility to malignant hyperthermia in man.
    British journal of anaesthesia, 1988, Volume: 60, Issue:3

    Topics: Caffeine; Chemistry, Clinical; Disease Susceptibility; Halothane; Hematologic Tests; Humans; In Vitr

1988

Trials

4 trials available for halothane and Diathesis

ArticleYear
Multicentre evaluation of in vitro contracture testing with bolus administration of 4-chloro-m-cresol for diagnosis of malignant hyperthermia susceptibility.
    European journal of anaesthesiology, 2003, Volume: 20, Issue:7

    Topics: Biopsy; Caffeine; Cresols; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant

2003
Prediction of malignant hyperthermia susceptibility in low-risk subjects. An epidemiologic investigation of caffeine halothane contracture responses. The North American Malignant Hyperthermia Registry.
    Anesthesiology, 1992, Volume: 76, Issue:1

    Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Child; Contracture; Disease Susceptibility; Female; Halot

1992
A blinded comparison of noninvasive, in vivo phosphorus nuclear magnetic resonance spectroscopy and the in vitro halothane/caffeine contracture test in the evaluation of malignant hyperthermia susceptibility.
    Anesthesia and analgesia, 1991, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Caffeine; Child; Child, Preschool; Disease Susceptibility; Female; Halothane; Hum

1991
Cytosolic free calcium concentrations in lymphocytes from malignant hyperthermia susceptible patients.
    British journal of anaesthesia, 1990, Volume: 64, Issue:3

    Topics: Adult; Aged; Benzofurans; Calcium; Child; Cytosol; Disease Susceptibility; Female; Fura-2; Halothane

1990

Other Studies

138 other studies available for halothane and Diathesis

ArticleYear
Management of patients susceptible to malignant hyperthermia: A surgeon's perspective.
    International journal of pediatric otorhinolaryngology, 2022, Volume: 159

    Topics: Caffeine; Child; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Retrospective St

2022
Distinct pathophysiological characteristics in developing muscle from patients susceptible to malignant hyperthermia.
    British journal of anaesthesia, 2023, Volume: 131, Issue:1

    Topics: Caffeine; Calcium; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Muscle Contrac

2023
Skeletal Muscle Metabolic Dysfunction in Patients With Malignant Hyperthermia Susceptibility.
    Anesthesia and analgesia, 2017, Volume: 125, Issue:2

    Topics: Adult; Anesthetics; Anthropometry; Caffeine; Case-Control Studies; Disease Susceptibility; Exercise

2017
Abnormal calcium signalling and the caffeine-halothane contracture test.
    British journal of anaesthesia, 2019, Volume: 122, Issue:1

    Topics: Adult; Anesthetics, Inhalation; Caffeine; Calcium; Cells, Cultured; Disease Susceptibility; Dose-Res

2019
Sevoflurane is less sensitive than halothane for in vitro detection of malignant hyperthermia susceptibility.
    Acta anaesthesiologica Scandinavica, 2013, Volume: 57, Issue:9

    Topics: Anesthetics, Inhalation; Biopsy; Disease Susceptibility; Dose-Response Relationship, Drug; Genetic P

2013
Is there a link between exertional heat stroke and susceptibility to malignant hyperthermia?
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adult; Anesthetics, Inhalation; Caffeine; Contracture; Disease Susceptibility; Female; Halothane; He

2015
An in-vivo metabolic test for detecting malignant hyperthermia susceptibility in humans: a pilot study.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:3

    Topics: Adult; Biopsy; Caffeine; Case-Control Studies; Disease Susceptibility; Female; Halothane; Humans; La

2008
Sevoflurane as a potential replacement for halothane in diagnostic testing for malignant hyperthermia susceptibility: results of a preliminary study.
    Minerva anestesiologica, 2011, Volume: 77, Issue:8

    Topics: Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Disease Susceptibility; Dose-R

2011
Halothane-induced calcium release in cultured human skeletal muscle cells from a family susceptible to malignant hyperthermia with an unidentified mutation in chromosome 19.
    Anesthesiology, 2002, Volume: 97, Issue:1

    Topics: Calcium; Cells, Cultured; Chromosomes, Human, Pair 19; Disease Susceptibility; Halothane; Humans; Ma

2002
Reproducibility of in vitro contracture test results in patients tested for malignant hyperthermia susceptibility.
    Acta anaesthesiologica Scandinavica, 2002, Volume: 46, Issue:9

    Topics: Adult; Anesthetics, Inhalation; Biopsy; Caffeine; Disease Susceptibility; Female; Halothane; Humans;

2002
"Noninvasive" testing for malignant hyperthermia susceptibility.
    Anesthesiology, 2002, Volume: 97, Issue:5

    Topics: Caffeine; Calcium; Cresols; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Muscl

2002
Patients with malignant hyperthermia demonstrate an altered calcium control mechanism in B lymphocytes.
    Anesthesiology, 2002, Volume: 97, Issue:5

    Topics: Adolescent; Adult; B-Lymphocytes; Caffeine; Calcium; Child; Cresols; Disease Susceptibility; Halotha

2002
Malignant hyperthermia: update on susceptibility testing.
    JAMA, 2005, Jun-15, Volume: 293, Issue:23

    Topics: Algorithms; B-Lymphocytes; Biopsy; Caffeine; Disease Susceptibility; DNA Mutational Analysis; Haloth

2005
The dose-response relationship and regional distribution of lactate after intramuscular injection of halothane and caffeine in malignant hyperthermia-susceptible pigs.
    Anesthesia and analgesia, 2006, Volume: 102, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Carbon Dioxide; Disease Susceptibility; Dose-Response Re

2006
Effects of ryanodine on skeletal muscle lactate and pyruvate in malignant hyperthermia-susceptible and normal swine as assessed by microdialysis.
    European journal of anaesthesiology, 2008, Volume: 25, Issue:1

    Topics: Animals; Caffeine; Disease Susceptibility; Halothane; Kinetics; Lactates; Malignant Hyperthermia; Mi

2008
A minimally invasive metabolic test with intramuscular injection of halothane 5 and 6 vol% to detect probands at risk for malignant hyperthermia.
    Anaesthesia, 2007, Volume: 62, Issue:9

    Topics: Adult; Anesthetics, Inhalation; Blood Pressure; Carbon Dioxide; Creatine Kinase; Disease Susceptibil

2007
[Halothane test in the selection of stress-negative swine].
    DTW. Deutsche tierarztliche Wochenschrift, 1984, May-07, Volume: 91, Issue:5

    Topics: Animals; Crosses, Genetic; Disease Susceptibility; Drug Tolerance; Female; Halothane; Male; Meat; St

1984
Investigation of malignant hyperthermia in Denmark and Sweden.
    British journal of anaesthesia, 1984, Volume: 56, Issue:11

    Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Child; Creatine Kinase; Disease Susceptibility; Female; G

1984
A protocol for the investigation of malignant hyperpyrexia (MH) susceptibility. The European Malignant Hyperpyrexia Group.
    British journal of anaesthesia, 1984, Volume: 56, Issue:11

    Topics: Biopsy; Caffeine; Disease Susceptibility; Genetic Testing; Halothane; Humans; In Vitro Techniques; M

1984
Halothane and halothane/succinylcholine induced malignant hyperthermia (porcine stress syndrome) in a population of Ontario boars.
    Canadian journal of comparative medicine : Revue canadienne de medecine comparee, 1983, Volume: 47, Issue:3

    Topics: Animals; Disease Susceptibility; Drug Combinations; Halothane; Male; Malignant Hyperthermia; Ontario

1983
Halothane stimulates the aggregation of platelets of both normal individuals and those susceptible to malignant hyperthermia.
    British journal of anaesthesia, 1983, Volume: 55, Issue:12

    Topics: Adenosine Diphosphate; Adolescent; Adult; Blood Platelets; Blood Proteins; Disease Susceptibility; F

1983
Failure to induce malignant hyperthermia in myotonic goats.
    British journal of anaesthesia, 1983, Volume: 55, Issue:1

    Topics: Animals; Disease Susceptibility; Goats; Halothane; Malignant Hyperthermia; Myotonia Congenita; Succi

1983
In vitro contracture tests for susceptibility to malignant hyperthermia.
    Anesthesia and analgesia, 1983, Volume: 62, Issue:4

    Topics: Caffeine; Disease Susceptibility; Drug Interactions; Halothane; Humans; Malignant Hyperthermia; Musc

1983
Spectrum of susceptibility to malignant hyperthermia--diagnostic dilemma.
    Anesthesia and analgesia, 1983, Volume: 62, Issue:6

    Topics: Animals; Body Temperature; Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques;

1983
Plasma dopamine-beta-hydroxylase and platelet monoamine oxidase activities in pigs with different susceptibility to the malignant hyperthermia syndrome by halothane.
    Reproduction, nutrition, developpement, 1981, Volume: 21, Issue:1

    Topics: Animals; Blood Platelets; Disease Susceptibility; Dopamine beta-Hydroxylase; Female; Halothane; Male

1981
Alterations of inositol polyphosphates in skeletal muscle during porcine malignant hyperthermia.
    British journal of anaesthesia, 1995, Volume: 75, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Chromatography, High Pressure Liquid; Dantrolene; Disease Suscepti

1995
C1840-T mutation in the human skeletal muscle ryanodine receptor gene: frequency in northern German families susceptible to malignant hyperthermia and the relationship to in vitro contracture response.
    Journal of molecular medicine (Berlin, Germany), 1995, Volume: 73, Issue:1

    Topics: Adolescent; Adult; Aged; Base Sequence; Caffeine; Calcium Channels; Child; Child, Preschool; Chromos

1995
Effect of cocaine on the contracture response to 1% halothane in patients undergoing diagnostic muscle biopsy for malignant hyperthermia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:2

    Topics: Adult; Biopsy; Caffeine; Cocaine; Contracture; Disease Susceptibility; Female; Halothane; Humans; Ma

1995
[Lack of sensitivity to per-anesthetic malignant hyperthermia in 32 patients who developed neuroleptic malignant syndrome].
    Annales francaises d'anesthesie et de reanimation, 1994, Volume: 13, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Caffeine; Contracture; Creatine Kinase; Dantrolene; Di

1994
Discordance, in a malignant hyperthermia pedigree, between in vitro contracture-test phenotypes and haplotypes for the MHS1 region on chromosome 19q12-13.2, comprising the C1840T transition in the RYR1 gene.
    American journal of human genetics, 1995, Volume: 56, Issue:6

    Topics: Calcium Channels; Chromosomes, Human, Pair 19; Contracture; Disease Susceptibility; Female; Genetic

1995
Incidence of malignant hyperthermia reactions in 2,214 patients undergoing muscle biopsy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Conduction; Anes

1995
Malignant hyperthermia during sevoflurane administration.
    Anesthesia and analgesia, 1995, Volume: 80, Issue:3

    Topics: Adult; Anesthetics; Caffeine; Disease Susceptibility; Ethers; Female; Halothane; Humans; Malignant H

1995
Masseter muscle rigidity and malignant hyperthermia susceptibility in pediatric patients. An update on management and diagnosis.
    Anesthesiology, 1994, Volume: 80, Issue:6

    Topics: Adolescent; Biopsy; Caffeine; Child; Child, Preschool; Creatine Kinase; Disease Susceptibility; Fema

1994
Genetic effects on the variability of the halothane and caffeine muscle contracture tests.
    Anesthesiology, 1994, Volume: 80, Issue:6

    Topics: Adult; Biopsy; Caffeine; Child; Disease Susceptibility; Family; Fatal Outcome; Female; Halothane; Hu

1994
Viability criterion of muscle bundles used in the in vitro contracture test in patients with neuromuscular diseases.
    British journal of anaesthesia, 1994, Volume: 72, Issue:1

    Topics: Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Me

1994
[Diagnosis of malignant hyperthermia susceptibility. 1. The significance of in vitro susceptibility tests].
    Der Anaesthesist, 1993, Volume: 42, Issue:10

    Topics: Adult; Caffeine; Child; Child, Preschool; Disease Susceptibility; Halothane; Humans; In Vitro Techni

1993
Relative accuracy of the halothane challenge test and a molecular genetic test in detecting the gene for porcine stress syndrome.
    Journal of animal science, 1993, Volume: 71, Issue:6

    Topics: Animals; Breeding; Calcium Channels; Disease Susceptibility; DNA; Female; Genotype; Halothane; Male;

1993
Phenotypes associated with malignant hyperthermia susceptibility in swine genotyped as homozygous or heterozygous for the ryanodine receptor mutation.
    British journal of anaesthesia, 1993, Volume: 71, Issue:3

    Topics: Animals; Base Sequence; Calcium; Calcium Channels; Disease Susceptibility; Genotype; Halothane; Hete

1993
Improved noninvasive diagnostic testing for malignant hyperthermia susceptibility from a combination of metabolites determined in vivo with 31P-magnetic resonance spectroscopy.
    Anesthesiology, 1993, Volume: 78, Issue:5

    Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Disease Susceptibility; Female; Halothane; Humans; Magnet

1993
Comparison of in vitro contracture testing with ryanodine, halothane and caffeine in malignant hyperthermia and other neuromuscular disorders.
    British journal of anaesthesia, 1993, Volume: 70, Issue:4

    Topics: Caffeine; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Tech

1993
Delayed onset of malignant hyperthermia induced by isoflurane and desflurane compared with halothane in susceptible swine.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Anesthetics; Animals; Desflurane; Disease Susceptibility; Halothane; Isoflurane; Malignant Hyperther

1993
On the nature of the link between malignant hyperthermia and exertional heatstroke.
    Medical hypotheses, 1995, Volume: 45, Issue:3

    Topics: Animals; Body Temperature Regulation; Caffeine; Calcium Channels; Disease Models, Animal; Disease Su

1995
Comparison of the segregation of the RYR1 C1840T mutation with segregation of the caffeine/halothane contracture test results for malignant hyperthermia susceptibility in a large Manitoba Mennonite family.
    Anesthesiology, 1996, Volume: 84, Issue:2

    Topics: Anesthetics, Inhalation; Caffeine; Disease Susceptibility; Female; Halothane; Heterozygote; Humans;

1996
Altered sodium current response to intracellular fatty acids in halothane-hypersensitive skeletal muscle.
    The American journal of physiology, 1996, Volume: 271, Issue:1 Pt 1

    Topics: Aging; Disease Susceptibility; Electric Conductivity; Fatty Acids; Halothane; Humans; Intracellular

1996
Response variability to ischemic injury in the Mongolian gerbil: an electroencephalographic and behavioral study.
    Italian journal of neurological sciences, 1996, Volume: 17, Issue:3

    Topics: Anesthesia, Inhalation; Animals; Behavior, Animal; Brain Ischemia; Carotid Arteries; Coma; Constrict

1996
Malignant hyperthermia.
    Acta anaesthesiologica Scandinavica. Supplementum, 1996, Volume: 109

    Topics: Anesthesia, General; Caffeine; Counseling; Disease Susceptibility; Halothane; Humans; Malignant Hype

1996
[Effect of acute stress on plasma levels of catecholamines and cortisol in addition to metabolites in stress-susceptible growing swine].
    Berliner und Munchener tierarztliche Wochenschrift, 1996, Volume: 109, Issue:10

    Topics: Animals; Blood Glucose; Disease Susceptibility; Epinephrine; Fatty Acids, Nonesterified; Halothane;

1996
[Definition of a diagnostic score of malignant hyperthermia using P-31 magnetic resonance spectroscopy].
    Annales francaises d'anesthesie et de reanimation, 1996, Volume: 15, Issue:5

    Topics: Caffeine; Contracture; Disease Susceptibility; Halothane; Humans; Magnetic Resonance Spectroscopy; M

1996
An analysis of the predictive probability of the in vitro contracture test for determining susceptibility to malignant hyperthermia.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:3

    Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Child; Contracture; Disease Susceptibility; Halothane; Hu

1997
Malignant hyperthermia testing in patients with persistently increased serum creatine kinase levels.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:5

    Topics: Adolescent; Adult; Anesthetics, Inhalation; Biopsy, Needle; Caffeine; Child; Child, Preschool; Clini

1997
Classification of malignant hyperthermia-equivocal patients by 4-chloro-M-cresol.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Cresols; Disease Susceptibility; Dose-Re

1997
Clinical reassessment of malignant hyperthermia in Abitibi-Témiscamingue.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:7

    Topics: Adolescent; Adult; Caffeine; Child; Disease Susceptibility; Family Characteristics; Female; Halothan

1997
[Effect of chlorocresol vs caffeine on muscle contracture in malignant hyperthermia susceptible patients].
    Harefuah, 1997, Jun-15, Volume: 132, Issue:12

    Topics: Adolescent; Adult; Caffeine; Cresols; Disease Susceptibility; Halothane; Humans; In Vitro Techniques

1997
Dystrophin deficient mdx muscle is not prone to MH susceptibility: an in vitro study.
    British journal of anaesthesia, 1997, Volume: 79, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Disease Susceptibility; Dystrophin; Halothane; Male; Mal

1997
4-Chloro-m-cresol test--a possible supplementary test for diagnosis of malignant hyperthermia susceptibility.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:8

    Topics: Biopsy; Caffeine; Cresols; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Huma

1997
Evaluation for malignant hyperthermia susceptibility in black-tailed deer.
    Journal of wildlife diseases, 1996, Volume: 32, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Blood Gas Analysis; Cardiac Output; Deer; Disease Susceptibility;

1996
Histological support for the difference between malignant hyperthermia susceptible (MHS), equivocal (MHE) and negative (MHN) muscle biopsies.
    British journal of anaesthesia, 1997, Volume: 79, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Atrophy; Biopsy; Disease Susceptibility; Female; H

1997
Muscle biopsy for malignant hyperthermia screening in children.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 1997, Volume: 7, Issue:5

    Topics: Adolescent; Anesthetics, Inhalation; Biopsy; Caffeine; Central Nervous System Stimulants; Child; Dis

1997
Rhabdomyolysis following severe physical exercise in a patient with predisposition to malignant hyperthermia.
    Anaesthesia and intensive care, 1998, Volume: 26, Issue:3

    Topics: Adult; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Disease Susceptibility;

1998
Large slow potential shifts occur during halothane anaesthesia in gerbils.
    Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 1998, Volume: 182, Issue:6

    Topics: Anesthesia; Animals; Behavior, Animal; Cerebral Cortex; Disease Susceptibility; Electrophysiology; G

1998
Inhalation anesthetics and Duchenne's muscular dystrophy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1999, Volume: 46, Issue:6

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Contraindications; Disease Susceptibility; Haloth

1999
Factitious halothane detection during trigger-free anesthesia in a malignant hyperthermia susceptible patient.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1999, Volume: 46, Issue:6

    Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Arthrodesis; Arthroscopy; Disease Susceptibilit

1999
Effects of halothane on mechanical response of skeletal muscle from malignant hyperthermia susceptible patients.
    Archives of physiology and biochemistry, 1998, Volume: 106, Issue:4

    Topics: Anesthetics, Inhalation; Biopsy; Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techn

1998
[Malignant hyperthermia susceptibility in 3 patients with malignant neuroleptic syndrome].
    Arquivos de neuro-psiquiatria, 2000, Volume: 58, Issue:3A

    Topics: Adult; Caffeine; Contracture; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hyp

2000
Evidence for susceptibility to malignant hyperthermia in patients with exercise-induced rhabdomyolysis.
    Anesthesiology, 2001, Volume: 94, Issue:1

    Topics: Adolescent; Adult; Anesthetics, Inhalation; Case-Control Studies; Child; Disease Susceptibility; Exe

2001
Halothane effects on human malignant hyperthermia skeletal muscle single calcium-release channels in planar lipid bilayers.
    Anesthesiology, 1992, Volume: 76, Issue:4

    Topics: Calcium Channels; Disease Susceptibility; Electric Stimulation; Halothane; Humans; Lipid Bilayers; M

1992
Evaluation of spin resonance spectroscopy of red blood cell membranes to detect malignant hyperthermia susceptibility.
    British journal of anaesthesia, 1992, Volume: 69, Issue:5

    Topics: Disease Susceptibility; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Halothane; Human

1992
Effect of Bay K 8644 on the magnitude of isoflurane and halothane contracture of skeletal muscle from patients susceptible to malignant hyperthermia.
    Anesthesiology, 1992, Volume: 76, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Evaluation of greyhound susceptibility to malignant hyperthermia using halothane-succinylcholine anesthesia and caffeine-halothane muscle contractures.
    Laboratory animal science, 1992, Volume: 42, Issue:5

    Topics: Anesthesia, Inhalation; Animals; Caffeine; Disease Susceptibility; Dog Diseases; Dogs; Genetic Predi

1992
Malignant hyperthermia susceptibility in patients with Duchenne's muscular dystrophy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:10

    Topics: Adolescent; Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Child; Child, Preschool; Disease

1992
Is the "K-type" caffeine-halothane responder susceptible to malignant hyperthermia?
    British journal of anaesthesia, 1992, Volume: 69, Issue:5

    Topics: Caffeine; Culture Techniques; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Mus

1992
Effect of halothane equilibration kinetics on in vitro muscle contractures for malignant hyperthermia screening.
    Acta anaesthesiologica Scandinavica, 1992, Volume: 36, Issue:2

    Topics: Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contr

1992
Propofol is a 'safe' anaesthetic agent in malignant hyperthermia susceptible patients.
    Anaesthesia and intensive care, 1992, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Caffeine; Contracture; Disease Susceptibility; Halothane

1992
[Effects of halothane, caffeine and ryanodine on the intracellular calcium store in blood mononuclear cells].
    Masui. The Japanese journal of anesthesiology, 1992, Volume: 41, Issue:5

    Topics: Animals; Caffeine; Calcium; Disease Susceptibility; Halothane; Humans; Leukocytes, Mononuclear; Mali

1992
The effects of volatile anesthetics on calcium regulation by malignant hyperthermia-susceptible sarcoplasmic reticulum.
    Anesthesiology, 1992, Volume: 77, Issue:1

    Topics: Animals; Calcium; Disease Susceptibility; Enflurane; Halothane; In Vitro Techniques; Isoflurane; Mal

1992
Evidence for related myopathies in exertional heat stroke and malignant hyperthermia.
    Lancet (London, England), 1991, Dec-14, Volume: 338, Issue:8781

    Topics: Adult; Biopsy; Caffeine; Disease Susceptibility; Family Health; Female; Halothane; Heat Exhaustion;

1991
Use of the calcium agonist BAY K 8644 for in vitro diagnosis of susceptibility to malignant hyperthermia.
    British journal of anaesthesia, 1990, Volume: 65, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Effects of calcium-free solution, calcium antagonists, and the calcium agonist BAY K 8644 on mechanical responses of skeletal muscle from patients susceptible to malignant hyperthermia.
    Anesthesiology, 1991, Volume: 75, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
EU 4093 decreases intracellular [Ca2+] in skeletal muscle fibers from control and malignant hyperthermia-susceptible swine.
    Anesthesiology, 1992, Volume: 76, Issue:1

    Topics: Animals; Calcium; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Imidazoles; M

1992
In vitro contracture tests in patients with various neuromuscular diseases.
    British journal of anaesthesia, 1992, Volume: 68, Issue:1

    Topics: Adolescent; Adult; Aged; Caffeine; Child; Child, Preschool; Disease Susceptibility; Drug Hypersensit

1992
[A new emphasis on the diagnosis of malignant hyperthermia using the in vitro contracture test?].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1991, Volume: 26, Issue:8

    Topics: Adolescent; Adult; Caffeine; Child; Child, Preschool; Disease Susceptibility; Halothane; Humans; In

1991
[Diagnosis of malignant hyperthermia. The platelet test versus the in vitro contracture test].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1991, Volume: 26, Issue:8

    Topics: Blood Platelets; Caffeine; Child; Disease Susceptibility; Halothane; Humans; Male; Malignant Hyperth

1991
In vitro contraction test for malignant hyperthermia in patients with unexplained recurrent rhabdomyolysis.
    Journal of the neurological sciences, 1991, Volume: 105, Issue:1

    Topics: Adult; Caffeine; Calcium; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hyperth

1991
Steal-prone coronary anatomy and myocardial ischemia associated with four primary anesthetic agents in humans.
    Anesthesia and analgesia, 1991, Volume: 72, Issue:1

    Topics: Anesthetics; Coronary Disease; Disease Susceptibility; Enflurane; Fentanyl; Halothane; Humans; Hypot

1991
In vitro contracture testing for determination of susceptibility to malignant hyperthermia: a methodologic update.
    Mayo Clinic proceedings, 1991, Volume: 66, Issue:10

    Topics: Caffeine; Chromatography, Gas; Contracture; Diffusion Chambers, Culture; Disease Susceptibility; Ele

1991
Effects of caffeine, halothane, succinylcholine, phenylephrine and isoproterenol on myocardial force of contraction of malignant hyperthermia susceptible swine.
    Acta anaesthesiologica Scandinavica, 1991, Volume: 35, Issue:4

    Topics: Animals; Caffeine; Disease Susceptibility; Halothane; Isoproterenol; Malignant Hyperthermia; Myocard

1991
Characterization of swine susceptible to malignant hyperthermia by in vivo, in vitro and post-mortem techniques.
    Acta anaesthesiologica Scandinavica, 1991, Volume: 35, Issue:4

    Topics: Administration, Inhalation; Animals; Caffeine; Creatine Kinase; Disease Susceptibility; Genotype; Ha

1991
[Malignant hyperthermia: halothane kinetics in a study model of muscular contraction. Head space determination and comparison with a mathematical model].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1991, Volume: 32, Issue:2

    Topics: Chromatography; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hypertherm

1991
Malignant hyperthermia: normal muscle calcium uptake and abnormal caffeine and halothane contractures.
    Anesthesiology, 1991, Volume: 75, Issue:3

    Topics: Adult; Biopsy; Caffeine; Calcium; Disease Susceptibility; False Negative Reactions; Female; Halothan

1991
Comparison of North American and European malignant hyperthermia group halothane contracture testing protocols in swine.
    Acta anaesthesiologica Scandinavica, 1991, Volume: 35, Issue:6

    Topics: Animals; Disease Susceptibility; Europe; Halothane; Malignant Hyperthermia; Muscle Contraction; Nort

1991
Enhanced mobilization of intracellular Ca2+ induced by halothane in hepatocytes isolated from swine susceptible to malignant hyperthermia.
    Anesthesiology, 1991, Volume: 74, Issue:3

    Topics: Animals; Calcium; Disease Susceptibility; Halothane; In Vitro Techniques; Ions; Liver; Malignant Hyp

1991
Halothane-dependent release of intracellular Ca2+ in blood cells in malignant hyperthermia.
    The American journal of physiology, 1990, Volume: 258, Issue:3 Pt 1

    Topics: Animals; Caffeine; Calcium; Cytosol; Disease Susceptibility; Egtazic Acid; Halothane; Humans; Malign

1990
Alterations in brain electrical activity may indicate the onset of malignant hyperthermia in swine.
    Anesthesiology, 1990, Volume: 73, Issue:6

    Topics: Anesthesia, Inhalation; Animals; Brain; Disease Susceptibility; Electroencephalography; Halothane; M

1990
Are myotonias and periodic paralyses associated with susceptibility to malignant hyperthermia?
    British journal of anaesthesia, 1990, Volume: 65, Issue:5

    Topics: Biopsy; Caffeine; Calcium; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant

1990
Caffeine and halothane contracture testing in swine using the recommendations of the North American Malignant Hyperthermia Group.
    Anesthesiology, 1990, Volume: 72, Issue:1

    Topics: Animals; Caffeine; Disease Susceptibility; Halothane; In Vitro Techniques; Malignant Hyperthermia; M

1990
Clinical concentrations of verapamil affect the in vitro diagnosis of susceptibility to malignant hyperpyrexia.
    British journal of anaesthesia, 1990, Volume: 64, Issue:1

    Topics: Caffeine; Disease Susceptibility; False Negative Reactions; Halothane; Humans; In Vitro Techniques;

1990
Safety of general anesthesia in patients previously tested negative for malignant hyperthermia susceptibility.
    Anesthesiology, 1990, Volume: 72, Issue:4

    Topics: Anesthesia, General; Caffeine; Contracture; Disease Susceptibility; Halothane; Humans; Malignant Hyp

1990
The effects of extracellular magnesium on myoplasmic [Ca2+] in malignant hyperthermia susceptible swine.
    Anesthesiology, 1990, Volume: 73, Issue:1

    Topics: Animals; Calcium; Dantrolene; Disease Susceptibility; Extracellular Space; Halothane; Magnesium Sulf

1990
Current diagnostic methods of malignant hyperthermia: an evaluation.
    Acta anaesthesiologica Belgica, 1990, Volume: 41, Issue:2

    Topics: Caffeine; Chromosomes, Human, Pair 19; Disease Susceptibility; Halothane; Humans; Magnetic Resonance

1990
Diltiazem and nifedipine reduce the in vitro contracture response to halothane in malignant hyperthermia-susceptible muscle.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:5

    Topics: Depression, Chemical; Diltiazem; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Mal

1990
Compensatory increase in calcium extrusion activity of untreated lymphocytes from swine susceptible to malignant hyperthermia.
    American journal of veterinary research, 1990, Volume: 51, Issue:7

    Topics: Animals; Caffeine; Calcium; Disease Susceptibility; Halothane; Lymphocytes; Malignant Hyperthermia;

1990
Porcine malignant hyperthermia: critical temperatures for in vivo and in vitro responses.
    Anesthesiology, 1990, Volume: 73, Issue:3

    Topics: Animals; Body Temperature; Calcium; Disease Susceptibility; Halothane; In Vitro Techniques; Malignan

1990
Malignant hyperthermia: slow sodium current in cultured human muscle cells.
    The American journal of physiology, 1989, Volume: 257, Issue:4 Pt 1

    Topics: Caffeine; Cells, Cultured; Disease Susceptibility; Electric Conductivity; Halothane; Humans; Maligna

1989
The association between the neuroleptic malignant syndrome and malignant hyperthermia.
    Acta anaesthesiologica Scandinavica, 1989, Volume: 33, Issue:8

    Topics: Adult; Caffeine; Chlorpromazine; Contracture; Disease Susceptibility; Female; Halothane; Humans; Mal

1989
Effect of diltiazem, verapamil and dantrolene on the contractility of isolated malignant hyperpyrexia-susceptible human skeletal muscle.
    Clinical and experimental pharmacology & physiology, 1989, Volume: 16, Issue:10

    Topics: Caffeine; Dantrolene; Diltiazem; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Mal

1989
[The action of ketamine on muscle contractile behavior. In vitro studies on the musculature of subjects susceptible to malignant hyperthermia].
    Der Anaesthesist, 1989, Volume: 38, Issue:12

    Topics: Caffeine; Disease Susceptibility; Halothane; In Vitro Techniques; Ketamine; Malignant Hyperthermia;

1989
Fluoxetine treatment of a depressed patient susceptible to malignant hyperthermia.
    The American journal of psychiatry, 1989, Volume: 146, Issue:5

    Topics: Adolescent; Caffeine; Depressive Disorder; Disease Susceptibility; Female; Fluoxetine; Halothane; Hu

1989
Influence of propranolol on the in vitro response to caffeine and halothane in malignant hyperthermia-susceptible muscle.
    Acta anaesthesiologica Scandinavica, 1989, Volume: 33, Issue:5

    Topics: Anesthesia; Caffeine; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Interactions; H

1989
Detection of malignant hyperthermia susceptibility using a spin label technique on red blood cells.
    British journal of anaesthesia, 1988, Volume: 61, Issue:5

    Topics: Cyclic N-Oxides; Disease Susceptibility; Electron Spin Resonance Spectroscopy; Erythrocytes; Halotha

1988
Porcine malignant hyperthermia susceptibility: halothane-induced increase in cytoplasmic free calcium in lymphocytes.
    American journal of veterinary research, 1989, Volume: 50, Issue:1

    Topics: Animals; Calcium; Cytosol; Disease Susceptibility; Halothane; Lymphocytes; Malignant Hyperthermia; S

1989
Preparation of anesthesia machines for patients susceptible to malignant hyperthermia.
    Anesthesiology, 1988, Volume: 69, Issue:3

    Topics: Anesthesia, Inhalation; Anesthesiology; Chromatography, Gas; Disease Susceptibility; Equipment Conta

1988
Malignant hyperthermia in plastic surgery.
    Plastic and reconstructive surgery, 1988, Volume: 82, Issue:5

    Topics: Adult; Caffeine; Child; Child, Preschool; Dermoid Cyst; Disease Susceptibility; Facial Neoplasms; Fe

1988
[Tests of contracture and sensitivity to malignant hyperthermia in 27 patients].
    Annales francaises d'anesthesie et de reanimation, 1988, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Anesthesia, General; Biopsy; Caffeine; Child; Child, Preschool; Contracture; Crea

1988
Plasma pyruvate kinase activity vs creatine kinase activity as an indicator of the porcine stress syndrome.
    American journal of veterinary research, 1988, Volume: 49, Issue:4

    Topics: Animals; Clinical Enzyme Tests; Creatine Kinase; Disease Susceptibility; Female; Halothane; Male; Ma

1988
Fura-2 detected myoplasmic calcium and its correlation with contracture force in skeletal muscle from normal and malignant hyperthermia susceptible pigs.
    Pflugers Archiv : European journal of physiology, 1988, Volume: 411, Issue:6

    Topics: Animals; Benzofurans; Caffeine; Calcium; Disease Susceptibility; Fura-2; Halothane; Malignant Hypert

1988
[Malignant hyperthermia in Austria. II. A comparison of the results of diagnostic test procedures].
    Der Anaesthesist, 1988, Volume: 37, Issue:7

    Topics: Adult; Caffeine; Creatine Kinase; Disease Susceptibility; Electromyography; Female; Halothane; Human

1988
Neuroleptic malignant syndrome and malignant hyperthermia. In vitro comparison with halothane and caffeine contracture tests.
    British journal of anaesthesia, 1987, Volume: 59, Issue:12

    Topics: Adult; Aged; Caffeine; Disease Susceptibility; Female; Halothane; Humans; In Vitro Techniques; Male;

1987
Porcine malignant hyperthermia: false negatives in the halothane test.
    American journal of veterinary research, 1987, Volume: 48, Issue:3

    Topics: Animals; Disease Susceptibility; False Negative Reactions; Genotype; Halothane; Malignant Hypertherm

1987
Platelet alterations in porcine stress syndrome.
    Veterinary research communications, 1987, Volume: 11, Issue:2

    Topics: Animals; Blood Platelets; Disease Susceptibility; Halothane; Male; Microscopy, Electron; Stress, Phy

1987
Malignant hyperthermia susceptibility in neuroleptic malignant syndrome.
    Anesthesiology, 1987, Volume: 67, Issue:1

    Topics: Adult; Disease Susceptibility; Female; Fluphenazine; Halothane; Humans; Male; Malignant Hyperthermia

1987
Effects of anaesthetic agents on erythrocyte fragility: comparison of normal and malignant hyperthermia susceptible patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1987, Volume: 34, Issue:4

    Topics: Disease Susceptibility; Ethanol; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Osm

1987
In vitro diagnosis of susceptibility to malignant hyperthermia: evaluation of tests with halothane-caffeine, potassium chloride, suxamethonium and caffeine-suxamethonium.
    Acta anaesthesiologica Scandinavica, 1987, Volume: 31, Issue:5

    Topics: Caffeine; Disease Susceptibility; Evaluation Studies as Topic; Halothane; Humans; In Vitro Technique

1987
In vitro diagnosis of susceptibility to malignant hyperthermia: comparison between dynamic and static halothane and caffeine tests.
    Acta anaesthesiologica Scandinavica, 1987, Volume: 31, Issue:5

    Topics: Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Mu

1987
Static v. dynamic tests in the in vitro diagnosis of malignant hyperthermia susceptibility.
    British journal of anaesthesia, 1986, Volume: 58, Issue:6

    Topics: Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Male; Malignant Hypertherm

1986
Genetic predisposition to liver damage after halothane anesthesia in guinea pigs.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:11

    Topics: Alanine Transaminase; Animals; Breeding; Chemical and Drug Induced Liver Injury; Disease Susceptibil

1986
[Examination of the family of a patient susceptible to anesthetic malignant hyperthermia].
    Annales francaises d'anesthesie et de reanimation, 1986, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Biopsy; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hypert

1986
In vitro muscle contractures induced by halothane and suxamethonium. II: Human skeletal muscle from normal and malignant hyperthermia susceptible patients.
    British journal of anaesthesia, 1986, Volume: 58, Issue:12

    Topics: Disease Susceptibility; Fatty Acids, Nonesterified; Halothane; Humans; In Vitro Techniques; Indometh

1986
HLA antigens in patients with unexplained hepatitis following halothane anesthesia.
    Acta anaesthesiologica Scandinavica, 1985, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthetics; Chemical and Drug Induced Liver Injury; Child; Cholestasis, In

1985
Malignant hyperthermia.
    Hospital practice (Office ed.), 1985, Mar-15, Volume: 20, Issue:3

    Topics: Adult; Anesthesia; Animals; Caffeine; Child; Creatine Kinase; Disease Susceptibility; Halothane; Hum

1985
Porcine malignant hyperthermia: cell injury enhances halothane sensitivity of biopsies.
    Muscle & nerve, 1986, Volume: 9, Issue:2

    Topics: Animals; Caffeine; Disease Susceptibility; Halothane; Hybridization, Genetic; In Vitro Techniques; M

1986
Malignant hyperpyrexia and sudden death.
    The American journal of forensic medicine and pathology, 1985, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Caffeine; Death, Sudden; Disease Susceptibility; Halothane; Humans; Male; Maligna

1985
In vitro interaction between halothane and succinylcholine in human skeletal muscle: implications for malignant hyperthermia and masseter muscle rigidity.
    Anesthesiology, 1985, Volume: 63, Issue:2

    Topics: Caffeine; Disease Susceptibility; Drug Interactions; Halothane; Humans; In Vitro Techniques; Maligna

1985
Porcine malignant hyperthermia susceptibility: erythrocytic osmotic fragility.
    American journal of veterinary research, 1985, Volume: 46, Issue:7

    Topics: Animals; Creatine Kinase; Crosses, Genetic; Disease Susceptibility; Erythrocytes; Glutathione Peroxi

1985
Laboratory diagnosis of malignant hyperpyrexia susceptibility (MHS). European MH Group.
    British journal of anaesthesia, 1985, Volume: 57, Issue:10

    Topics: Caffeine; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia

1985
Microcalorimetric studies in malignant hyperpyrexia susceptible individuals.
    British journal of anaesthesia, 1985, Volume: 57, Issue:10

    Topics: Blood Platelets; Body Temperature Regulation; Caffeine; Calorimetry; Disease Susceptibility; Halotha

1985
Diltiazem inhibits halothane-induced contractions in malignant hyperthermia-susceptible muscles in vitro.
    British journal of anaesthesia, 1985, Volume: 57, Issue:10

    Topics: Animals; Benzazepines; Caffeine; Depression, Chemical; Diltiazem; Disease Susceptibility; Halothane;

1985
Halothane hepatitis. Detection of a constitutional susceptibility factor.
    The New England journal of medicine, 1985, Nov-21, Volume: 313, Issue:21

    Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Disease Susceptibility; Drug Evaluation, Precli

1985
Myoadenylate deaminase deficiency and malignant hyperthermia susceptibility: is there a relationship?
    Biochemical medicine, 1985, Volume: 34, Issue:3

    Topics: Adenylate Kinase; Adult; AMP Deaminase; Caffeine; Creatine Kinase; Disease Susceptibility; Female; H

1985