Page last updated: 2024-10-28

halothane and Delirium

halothane has been researched along with Delirium in 9 studies

Delirium: A disorder characterized by CONFUSION; inattentiveness; disorientation; ILLUSIONS; HALLUCINATIONS; agitation; and in some instances autonomic nervous system overactivity. It may result from toxic/metabolic conditions or structural brain lesions. (From Adams et al., Principles of Neurology, 6th ed, pp411-2)

Research Excerpts

ExcerptRelevanceReference
"The subjects were 83 premedicated children aged 1 to 6 years who underwent surgical procedures with propofol (group P, n=41) or with halothane (group H, n=42) anesthesia."9.14Emergence agitation in children after propofol versus halothane anesthesia. ( Baftiu, N; Hasani, A; Ozgen, S, 2009)
"Sevoflurane provided quicker emergence and early recovery compared with halothane, but the incidence of delirium was greater in preschool boys after sevoflurane."9.08Greater incidence of delirium during recovery from sevoflurane anesthesia in preschool boys. ( Aono, J; Mamiya, K; Manabe, M; Takimoto, E; Ueda, W, 1997)
"The subjects were 83 premedicated children aged 1 to 6 years who underwent surgical procedures with propofol (group P, n=41) or with halothane (group H, n=42) anesthesia."5.14Emergence agitation in children after propofol versus halothane anesthesia. ( Baftiu, N; Hasani, A; Ozgen, S, 2009)
"The authors found no increased incidence of emergence delirium, maladaptive postoperative behavior changes, or sleep disturbances in children undergoing anesthesia with sevoflurane as compared with halothane."5.11Sevoflurane versus halothane: postoperative maladaptive behavioral changes: a randomized, controlled trial. ( Caldwell-Andrews, AA; Gaal, D; Kain, ZN; Maranets, I; Mayes, LC; Saadat, H; Wang, SM; Weinberg, ME, 2005)
"Sevoflurane provided quicker emergence and early recovery compared with halothane, but the incidence of delirium was greater in preschool boys after sevoflurane."5.08Greater incidence of delirium during recovery from sevoflurane anesthesia in preschool boys. ( Aono, J; Mamiya, K; Manabe, M; Takimoto, E; Ueda, W, 1997)
"Torsade de pointes (TdP) occurred in a long QT syndrome type 3 (LQT3) patient after switching perospirone to blonanserin."3.96Experimental analysis of the onset mechanism of TdP reported in an LQT3 patient during pharmacological treatment with serotonin-dopamine antagonists against insomnia and nocturnal delirium. ( Chiba, K; Goto, A; Hagiwara-Nagasawa, M; Izumi-Nakaseko, H; Kambayashi, R; Matsumoto, A; Naito, AT; Sugiyama, A, 2020)
"Delirium is a common mental disorder with serious adverse outcomes in hospitalised patients."2.44Interventions for preventing delirium in hospitalised patients. ( Britton, AM; Holmes, J; Siddiqi, N; Stockdale, R, 2007)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's3 (33.33)18.2507
2000's4 (44.44)29.6817
2010's0 (0.00)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Kambayashi, R1
Hagiwara-Nagasawa, M1
Goto, A1
Chiba, K1
Izumi-Nakaseko, H1
Naito, AT1
Matsumoto, A1
Sugiyama, A1
Hasani, A1
Ozgen, S1
Baftiu, N1
Kain, ZN1
Caldwell-Andrews, AA1
Weinberg, ME1
Mayes, LC1
Wang, SM1
Gaal, D1
Saadat, H1
Maranets, I1
Siddiqi, N1
Stockdale, R1
Britton, AM1
Holmes, J1
Aono, J2
Ueda, W1
Mamiya, K2
Takimoto, E1
Manabe, M2
Holzki, J1
Kretz, FJ1
Cravero, J1
Surgenor, S1
Whalen, K1
Jacobi McNeil, AG1

Clinical Trials (11)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Dexmedetomidine on Long-term Outcome in Elderly Patients After Noncardiac Surgery: 3-year Follow-up of a Randomized Controlled Trial[NCT02809937]Phase 4700 participants (Actual)Interventional2011-05-31Completed
Pilot Study of a Multicomponent Nurse Intervention to Reduce the Incidence and Severity of Delirium in Hospitalized Older Adults: MID-Nurse-P[NCT02558777]50 participants (Actual)Interventional2013-10-31Completed
The Preventative Role of Exogenous Melatonin Administration in Patients With Advanced Cancer Who Are at Risk of Delirium: a Feasibility Study Prior to a Larger Randomized Controlled Trial[NCT02200172]Phase 260 participants (Actual)Interventional2014-12-31Completed
Impact of Dexmedetomidine on Long-term Outcome in Elderly Patients After Noncardiac Surgery: 5-year Follow-up of a Randomized Controlled Trial[NCT03436472]700 participants (Actual)Interventional2017-06-01Completed
Effect of Intravenous Nalbuphine on Emergence Agitation in Children Undergoing Repair of Rupture Globe[NCT03470077]Phase 280 participants (Actual)Interventional2019-07-31Completed
A Comparison of Postoperative Emergence Agitation by Sevoflurane for Intraoperative Sedation Associated With Caudal Block in Children: Randomised Comparison of Two Dose[NCT03134547]40 participants (Actual)Interventional2016-06-01Completed
Use of Handheld Audiovisual Devices to Treat Pediatric Preoperative Anxiety: A Randomized Control Trial.[NCT02286674]200 participants (Actual)Interventional2014-11-30Completed
Effectivity of 0.5 mg/kg Propofol in the End of Anesthesia to Reduce the Incidence of Postanesthetic Emergence Agitation in Pediatric Patients Under General Inhalation Anesthesia[NCT03528954]54 participants (Actual)Interventional2018-05-31Completed
Prospective Cohort Study Evaluating Incidence and Correlation Between Pain and Emergence Delirium After Adenotonsillectomy in Preschool Children[NCT01096797]Phase 4150 participants (Actual)Interventional2009-11-30Completed
Efficacy and Safety of Esketamine or Sevoflurane Add to Dexmedetomidine-based Sedation for Ophthalmology Procedure in Children[NCT05321160]116 participants (Actual)Interventional2021-03-10Completed
Intranasal Dexmedetomidine Decreases Emergence Delirium in Pediatric Patients After Sevoflurane Based General Anesthesia[NCT00778063]40 participants (Actual)Interventional2008-09-30Terminated (stopped due to Difficulty enrolling patients)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for halothane and Delirium

ArticleYear
Interventions for preventing delirium in hospitalised patients.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Anesthesia, Epidural; Anesthetics, Inhalation; Cytidine Diphosphate Choline; Delirium; Donepezil; Ha

2007
Interventions for preventing delirium in hospitalised patients.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Anesthesia, Epidural; Anesthetics, Inhalation; Cytidine Diphosphate Choline; Delirium; Donepezil; Ha

2007
Interventions for preventing delirium in hospitalised patients.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Anesthesia, Epidural; Anesthetics, Inhalation; Cytidine Diphosphate Choline; Delirium; Donepezil; Ha

2007
Interventions for preventing delirium in hospitalised patients.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Anesthesia, Epidural; Anesthetics, Inhalation; Cytidine Diphosphate Choline; Delirium; Donepezil; Ha

2007
Interventions for preventing delirium in hospitalised patients.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Anesthesia, Epidural; Anesthetics, Inhalation; Cytidine Diphosphate Choline; Delirium; Donepezil; Ha

2007
Interventions for preventing delirium in hospitalised patients.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Anesthesia, Epidural; Anesthetics, Inhalation; Cytidine Diphosphate Choline; Delirium; Donepezil; Ha

2007
Interventions for preventing delirium in hospitalised patients.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Anesthesia, Epidural; Anesthetics, Inhalation; Cytidine Diphosphate Choline; Delirium; Donepezil; Ha

2007
Interventions for preventing delirium in hospitalised patients.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Anesthesia, Epidural; Anesthetics, Inhalation; Cytidine Diphosphate Choline; Delirium; Donepezil; Ha

2007
Interventions for preventing delirium in hospitalised patients.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Anesthesia, Epidural; Anesthetics, Inhalation; Cytidine Diphosphate Choline; Delirium; Donepezil; Ha

2007
Interventions for preventing delirium in hospitalised patients.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Anesthesia, Epidural; Anesthetics, Inhalation; Cytidine Diphosphate Choline; Delirium; Donepezil; Ha

2007
Interventions for preventing delirium in hospitalised patients.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Anesthesia, Epidural; Anesthetics, Inhalation; Cytidine Diphosphate Choline; Delirium; Donepezil; Ha

2007
Interventions for preventing delirium in hospitalised patients.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Anesthesia, Epidural; Anesthetics, Inhalation; Cytidine Diphosphate Choline; Delirium; Donepezil; Ha

2007
Interventions for preventing delirium in hospitalised patients.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Anesthesia, Epidural; Anesthetics, Inhalation; Cytidine Diphosphate Choline; Delirium; Donepezil; Ha

2007
Interventions for preventing delirium in hospitalised patients.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Anesthesia, Epidural; Anesthetics, Inhalation; Cytidine Diphosphate Choline; Delirium; Donepezil; Ha

2007
Interventions for preventing delirium in hospitalised patients.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Anesthesia, Epidural; Anesthetics, Inhalation; Cytidine Diphosphate Choline; Delirium; Donepezil; Ha

2007
Interventions for preventing delirium in hospitalised patients.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Anesthesia, Epidural; Anesthetics, Inhalation; Cytidine Diphosphate Choline; Delirium; Donepezil; Ha

2007

Trials

4 trials available for halothane and Delirium

ArticleYear
Emergence agitation in children after propofol versus halothane anesthesia.
    Medical science monitor : international medical journal of experimental and clinical research, 2009, Volume: 15, Issue:6

    Topics: Anesthesia; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; De

2009
Sevoflurane versus halothane: postoperative maladaptive behavioral changes: a randomized, controlled trial.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthetics, Inhalation; Anxiety; Child;

2005
Greater incidence of delirium during recovery from sevoflurane anesthesia in preschool boys.
    Anesthesiology, 1997, Volume: 87, Issue:6

    Topics: Age Factors; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Chi

1997
Greater incidence of delirium during recovery from sevoflurane anesthesia in preschool boys.
    Anesthesiology, 1997, Volume: 87, Issue:6

    Topics: Age Factors; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Chi

1997
Greater incidence of delirium during recovery from sevoflurane anesthesia in preschool boys.
    Anesthesiology, 1997, Volume: 87, Issue:6

    Topics: Age Factors; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Chi

1997
Greater incidence of delirium during recovery from sevoflurane anesthesia in preschool boys.
    Anesthesiology, 1997, Volume: 87, Issue:6

    Topics: Age Factors; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Chi

1997
Emergence agitation in paediatric patients after sevoflurane anaesthesia and no surgery: a comparison with halothane.
    Paediatric anaesthesia, 2000, Volume: 10, Issue:4

    Topics: Ambulatory Care; Anesthesia Recovery Period; Anesthetics, Inhalation; Chi-Square Distribution; Child

2000
Emergence agitation in paediatric patients after sevoflurane anaesthesia and no surgery: a comparison with halothane.
    Paediatric anaesthesia, 2000, Volume: 10, Issue:4

    Topics: Ambulatory Care; Anesthesia Recovery Period; Anesthetics, Inhalation; Chi-Square Distribution; Child

2000
Emergence agitation in paediatric patients after sevoflurane anaesthesia and no surgery: a comparison with halothane.
    Paediatric anaesthesia, 2000, Volume: 10, Issue:4

    Topics: Ambulatory Care; Anesthesia Recovery Period; Anesthetics, Inhalation; Chi-Square Distribution; Child

2000
Emergence agitation in paediatric patients after sevoflurane anaesthesia and no surgery: a comparison with halothane.
    Paediatric anaesthesia, 2000, Volume: 10, Issue:4

    Topics: Ambulatory Care; Anesthesia Recovery Period; Anesthetics, Inhalation; Chi-Square Distribution; Child

2000

Other Studies

4 other studies available for halothane and Delirium

ArticleYear
Experimental analysis of the onset mechanism of TdP reported in an LQT3 patient during pharmacological treatment with serotonin-dopamine antagonists against insomnia and nocturnal delirium.
    Heart and vessels, 2020, Volume: 35, Issue:4

    Topics: Action Potentials; Anesthetics, Inhalation; Animals; Calcium Channel Agonists; Cardiac Conduction Sy

2020
Preoperative anxiety is associated with a high incidence of problematic behavior on emergence after halothane anesthesia in boys.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:5

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Anxiety; Awareness; Bupivacaine

1999
Preoperative anxiety is associated with a high incidence of problematic behavior on emergence after halothane anesthesia in boys.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:5

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Anxiety; Awareness; Bupivacaine

1999
Preoperative anxiety is associated with a high incidence of problematic behavior on emergence after halothane anesthesia in boys.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:5

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Anxiety; Awareness; Bupivacaine

1999
Preoperative anxiety is associated with a high incidence of problematic behavior on emergence after halothane anesthesia in boys.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:5

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Anxiety; Awareness; Bupivacaine

1999
Changing aspects of sevoflurane in paediatric anaesthesia: 1975-99.
    Paediatric anaesthesia, 1999, Volume: 9, Issue:4

    Topics: Akathisia, Drug-Induced; Anesthesia, Inhalation; Anesthetics, Inhalation; Arrhythmias, Cardiac; Chil

1999
Pain control--the team approach.
    Dental clinics of North America, 1975, Volume: 19, Issue:4

    Topics: Anesthesia, Dental; Anesthesiology; Blood Pressure; Cardiovascular Diseases; Delirium; Dental Servic

1975