halothane has been researched along with Cholestasis in 33 studies
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The following parameters were estimated the day before surgery and on the first postoperative day: liver cell metabolism (bile acids, unconjugated bilirubin), cell integrity (aminotransferases), synthesizing capacity (Prothrombin complex), cholestasis (conjugated bilirubin, alkaline phosphatase, gamma-glutamyl transpeptidase), and global liver function (chenodeoxycholic load test)." | 5.08 | Liver function and halothane-diethyl-ether azeotrope anaesthesia. Re-evaluation of an obsolete drug with special reference to early postoperative effects. ( Bengtsson, M; Kalman, SH; Mårtensson, J, 1995) |
| "Most adverse drug reactions affecting the liver and producing jaundice are unpredictable, delayed in onset, and only hypothetically related to microsomal metabolism in some instances." | 2.35 | Hepatic drug metabolism and adverse hepatic drug reactions. ( Schaffner, F, 1975) |
| "Halothane was the only anesthetic used throughout the studies." | 1.28 | [Is MAC effected by liver dysfunction?--Bilirubin and MAC]. ( Kimura, J; Kobayashi, K; Tanifuji, Y; Yasuda, N, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (87.88) | 18.7374 |
| 1990's | 4 (12.12) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Siegers, CP | 1 |
| Mackenroth, T | 1 |
| Wächter, S | 1 |
| Younes, M | 1 |
| Kalman, SH | 1 |
| Bengtsson, M | 1 |
| Mårtensson, J | 1 |
| Frost, L | 1 |
| Mahoney, J | 1 |
| Field, J | 1 |
| Farrell, GC | 1 |
| Schaffner, F | 1 |
| Lai, MY | 1 |
| Sung, JL | 1 |
| Lin, WS | 1 |
| How, SW | 1 |
| Yu, JY | 1 |
| Wang, TH | 1 |
| Chen, DS | 1 |
| Maddrey, WC | 1 |
| Boitnott, JK | 1 |
| Nunez-Gornes, JF | 1 |
| Marx, JJ | 1 |
| Motszko, C | 1 |
| Sherlock, S | 1 |
| Cerf, M | 1 |
| Strohmeyer, G | 1 |
| Berges, W | 1 |
| Talbot, IC | 1 |
| Zimmerman, HJ | 1 |
| Bianchi, L | 1 |
| De Groote, J | 1 |
| Desmet, V | 1 |
| Gedigk, P | 1 |
| Korb, G | 1 |
| Popper, H | 1 |
| Poulsen, H | 1 |
| Scheuer, PJ | 1 |
| Schmid, M | 1 |
| Thaler, H | 1 |
| Wepler, W | 1 |
| Erlinger, S | 1 |
| Prandi, D | 1 |
| Knoblauch, M | 1 |
| Lämmli, J | 1 |
| Funk, C | 1 |
| Yasuda, N | 1 |
| Tanifuji, Y | 1 |
| Kobayashi, K | 1 |
| Kimura, J | 1 |
| Bomzon, A | 1 |
| Monies-Chass, I | 1 |
| Kamenetz, L | 1 |
| Blendis, L | 1 |
| Klinge, O | 1 |
| Versieck, J | 1 |
| Van Waes, L | 1 |
| Barbier, F | 1 |
| Demeulenaere, L | 1 |
| Vermeire, P | 1 |
| LaMont, JT | 2 |
| Isselbacher, KJ | 1 |
| Fossati, C | 1 |
| Neuvonen, P | 1 |
| Scholler, KL | 1 |
| Franken, FH | 1 |
| Kirchmayer, S | 1 |
| Geall, MG | 1 |
| Webb, MJ | 1 |
| Bode, C | 1 |
| Martini, GA | 1 |
| Holden, TE | 1 |
| Sherline, DM | 1 |
| Peters, RL | 1 |
| Edmondson, HA | 1 |
| Reynolds, TB | 1 |
| Meister, JC | 1 |
| Curpey, TJ | 1 |
| Pintér, A | 1 |
| Tekeres, M | 1 |
| Gattiker, R | 1 |
10 reviews available for halothane and Cholestasis
| Article | Year |
|---|---|
Hepatic drug metabolism and adverse hepatic drug reactions.
Topics: Adaptation, Biological; Animals; Biotransformation; Carbon Tetrachloride; Carbon Tetrachloride Poiso | 1975 |
Biochemical and morphological study of the liver injury induced by drugs and chemicals.
Topics: Alkaline Phosphatase; Aspirin; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Halothan | 1979 |
Drug-induced chronic hepatitis and cirrhosis.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adve | 1979 |
Acute liver injury.
Topics: Acetaminophen; Acute Disease; Chemical and Drug Induced Liver Injury; Cholestasis; Halothane; Hepati | 1975 |
Postoperative jaundice.
Topics: Bacterial Infections; Bile Pigments; Bilirubin; Chemical and Drug Induced Liver Injury; Cholecystiti | 1973 |
[Liver damage due to drugs. I].
Topics: Arsenicals; Chemical and Drug Induced Liver Injury; Chloramphenicol; Cholestasis; Coumarins; Drug-Re | 1974 |
Postoperative juandice.
Topics: Aminosalicylic Acids; Anemia, Hemolytic; Bile Ducts; Bilirubin; Chemical and Drug Induced Liver Inju | 1974 |
[Drug induced liver diseases].
Topics: Aminosalicylic Acids; Animals; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholestasis; | 1974 |
[Anesthesiologic problems in liver diseases].
Topics: Anesthesia; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Spinal; Cholestasis; Germany, Wes | 1974 |
[Toxic liver injury].
Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Cholestyramine Resin; Contraceptives, Oral; Dia | 1970 |
1 trial available for halothane and Cholestasis
| Article | Year |
|---|---|
Liver function and halothane-diethyl-ether azeotrope anaesthesia. Re-evaluation of an obsolete drug with special reference to early postoperative effects.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Spinal; Bile Acids and Salts; Bilirubin; Cholestasi | 1995 |
22 other studies available for halothane and Cholestasis
| Article | Year |
|---|---|
Effects of liver injury and cholestasis on microsomal enzyme activities and metabolism of halothane, enflurane and methoxyflurane in vivo in rats.
Topics: Anesthetics; Animals; Carbon Tetrachloride Poisoning; Cholestasis; Enflurane; Half-Life; Halothane; | 1981 |
Impaired bile flow and disordered hepatic calcium homeostasis are early features of halothane-induced liver injury in guinea pigs.
Topics: Animals; Bile; Bile Acids and Salts; Biological Transport; Calcium; Cell Membrane Permeability; Chol | 1996 |
Leukocyte migration inhibition in halothane-induced hepatitis.
Topics: Adult; Aged; Cell Migration Inhibition; Chemical and Drug Induced Liver Injury; Cholelithiasis; Chol | 1979 |
Hepatic reactions to drugs.
Topics: Acetaminophen; Adenoma; Adult; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur | 1979 |
[Postoperative medical jaundice (author's transl)].
Topics: Bacterial Infections; Chemical and Drug Induced Liver Injury; Cholestasis; Halothane; Hemolysis; Hum | 1978 |
[Postoperative icterus].
Topics: Blood; Cholestasis; Diagnosis, Differential; Halothane; Hemolysis; Hemorrhage; Hepatitis; Humans; Hy | 1976 |
Liver disease caused by medicinal agents.
Topics: Adrenal Cortex Hormones; Analgesics; Chemical and Drug Induced Liver Injury; Cholestasis; Contracept | 1975 |
[Rules for the histological evaluation of drug-induced liver lesions].
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholestasis; Contraceptives, Oral; F | 1975 |
[Postoperative icterus].
Topics: Anesthesia, Inhalation; Bacterial Infections; Chemical and Drug Induced Liver Injury; Cholestasis; H | 1975 |
[Drug-induced liver diseases].
Topics: Acetaminophen; Adult; Alcoholism; Azathioprine; Bilirubin; Chemical and Drug Induced Liver Injury; C | 1975 |
[Is MAC effected by liver dysfunction?--Bilirubin and MAC].
Topics: Anesthesia, Inhalation; Animals; Bilirubin; Cholestasis; Dogs; Halothane | 1990 |
Anesthesia and pressor responsiveness in chronic bile-duct-ligated dogs.
Topics: Anesthesia; Angiotensin II; Animals; Bile Ducts; Blood Pressure; Cholestasis; Dogs; Fentanyl; Haloth | 1990 |
[Morphology and etiology of halothane-induced liver lesions (author's transl)].
Topics: Adult; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Child; Cholestasis; Fatty Liv | 1972 |
Guidelines for diagnosis of therapeutic drug-induced liver injury in liver biopsies.
Topics: Anabolic Agents; Biopsy; Cathartics; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholest | 1974 |
Peritoneoscopy during hepatic coma.
Topics: Adolescent; Adult; Aged; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Haloth | 1973 |
[Sedatives and liver diseases].
Topics: Barbiturates; Chemical and Drug Induced Liver Injury; Cholestasis; Halothane; Humans; Hypnotics and | 1973 |
[Drug-induced hepatopathies].
Topics: Adult; Age Factors; Bilirubin; Cell Membrane; Chemical and Drug Induced Liver Injury; Cholestasis; D | 1974 |
Liver disease in pregnancy.
Topics: Acute Kidney Injury; Chemical and Drug Induced Liver Injury; Cholestasis; Contraceptives, Oral; Fatt | 1974 |
Hepatitis and hepatic failure in pregnancy.
Topics: Cholestasis; Fatty Liver; Female; Halothane; Hepatitis; Hepatitis A; Hepatitis B; Hepatitis B Antige | 1972 |
Hepatic necrosis associated with halothane anesthesia.
Topics: Anesthesia; Autopsy; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis; Collagen; Connecti | 1969 |
The effect of halothane in the rat with experimental obstructive juandice.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bilirubin; Blood Proteins; Cholestasis; Female; | 1968 |
[Benign postoperative intrahepatic cholestasis].
Topics: Anesthesia, Inhalation; Blood Transfusion; Cholestasis; Halothane; Humans; Neuroleptanalgesia; Posto | 1966 |