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halothane and Cholestasis

halothane has been researched along with Cholestasis in 33 studies

Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).

Research Excerpts

ExcerptRelevanceReference
" The following parameters were estimated the day before surgery and on the first postoperative day: liver cell metabolism (bile acids, unconjugated bilirubin), cell integrity (aminotransferases), synthesizing capacity (Prothrombin complex), cholestasis (conjugated bilirubin, alkaline phosphatase, gamma-glutamyl transpeptidase), and global liver function (chenodeoxycholic load test)."5.08Liver function and halothane-diethyl-ether azeotrope anaesthesia. Re-evaluation of an obsolete drug with special reference to early postoperative effects. ( Bengtsson, M; Kalman, SH; Mårtensson, J, 1995)
"Most adverse drug reactions affecting the liver and producing jaundice are unpredictable, delayed in onset, and only hypothetically related to microsomal metabolism in some instances."2.35Hepatic drug metabolism and adverse hepatic drug reactions. ( Schaffner, F, 1975)
"Halothane was the only anesthetic used throughout the studies."1.28[Is MAC effected by liver dysfunction?--Bilirubin and MAC]. ( Kimura, J; Kobayashi, K; Tanifuji, Y; Yasuda, N, 1990)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199029 (87.88)18.7374
1990's4 (12.12)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Siegers, CP1
Mackenroth, T1
Wächter, S1
Younes, M1
Kalman, SH1
Bengtsson, M1
Mårtensson, J1
Frost, L1
Mahoney, J1
Field, J1
Farrell, GC1
Schaffner, F1
Lai, MY1
Sung, JL1
Lin, WS1
How, SW1
Yu, JY1
Wang, TH1
Chen, DS1
Maddrey, WC1
Boitnott, JK1
Nunez-Gornes, JF1
Marx, JJ1
Motszko, C1
Sherlock, S1
Cerf, M1
Strohmeyer, G1
Berges, W1
Talbot, IC1
Zimmerman, HJ1
Bianchi, L1
De Groote, J1
Desmet, V1
Gedigk, P1
Korb, G1
Popper, H1
Poulsen, H1
Scheuer, PJ1
Schmid, M1
Thaler, H1
Wepler, W1
Erlinger, S1
Prandi, D1
Knoblauch, M1
Lämmli, J1
Funk, C1
Yasuda, N1
Tanifuji, Y1
Kobayashi, K1
Kimura, J1
Bomzon, A1
Monies-Chass, I1
Kamenetz, L1
Blendis, L1
Klinge, O1
Versieck, J1
Van Waes, L1
Barbier, F1
Demeulenaere, L1
Vermeire, P1
LaMont, JT2
Isselbacher, KJ1
Fossati, C1
Neuvonen, P1
Scholler, KL1
Franken, FH1
Kirchmayer, S1
Geall, MG1
Webb, MJ1
Bode, C1
Martini, GA1
Holden, TE1
Sherline, DM1
Peters, RL1
Edmondson, HA1
Reynolds, TB1
Meister, JC1
Curpey, TJ1
Pintér, A1
Tekeres, M1
Gattiker, R1

Reviews

10 reviews available for halothane and Cholestasis

ArticleYear
Hepatic drug metabolism and adverse hepatic drug reactions.
    Veterinary pathology, 1975, Volume: 12, Issue:2

    Topics: Adaptation, Biological; Animals; Biotransformation; Carbon Tetrachloride; Carbon Tetrachloride Poiso

1975
Biochemical and morphological study of the liver injury induced by drugs and chemicals.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1979, Volume: 78, Issue:6

    Topics: Alkaline Phosphatase; Aspirin; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Halothan

1979
Drug-induced chronic hepatitis and cirrhosis.
    Progress in liver diseases, 1979, Volume: 6

    Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adve

1979
Acute liver injury.
    Journal of clinical pathology. Supplement (Royal College of Pathologists), 1975, Volume: 9

    Topics: Acetaminophen; Acute Disease; Chemical and Drug Induced Liver Injury; Cholestasis; Halothane; Hepati

1975
Postoperative jaundice.
    The New England journal of medicine, 1973, Feb-08, Volume: 288, Issue:6

    Topics: Bacterial Infections; Bile Pigments; Bilirubin; Chemical and Drug Induced Liver Injury; Cholecystiti

1973
[Liver damage due to drugs. I].
    La Clinica terapeutica, 1974, Jan-15, Volume: 68, Issue:1

    Topics: Arsenicals; Chemical and Drug Induced Liver Injury; Chloramphenicol; Cholestasis; Coumarins; Drug-Re

1974
Postoperative juandice.
    The Surgical clinics of North America, 1974, Volume: 54, Issue:3

    Topics: Aminosalicylic Acids; Anemia, Hemolytic; Bile Ducts; Bilirubin; Chemical and Drug Induced Liver Inju

1974
[Drug induced liver diseases].
    Duodecim; laaketieteellinen aikakauskirja, 1974, Volume: 90, Issue:20

    Topics: Aminosalicylic Acids; Animals; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholestasis;

1974
[Anesthesiologic problems in liver diseases].
    Medizinische Klinik, 1974, Sep-27, Volume: 69, Issue:39

    Topics: Anesthesia; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Spinal; Cholestasis; Germany, Wes

1974
[Toxic liver injury].
    Medizinische Klinik, 1970, Jan-02, Volume: 65, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Cholestyramine Resin; Contraceptives, Oral; Dia

1970

Trials

1 trial available for halothane and Cholestasis

ArticleYear
Liver function and halothane-diethyl-ether azeotrope anaesthesia. Re-evaluation of an obsolete drug with special reference to early postoperative effects.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:1

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Spinal; Bile Acids and Salts; Bilirubin; Cholestasi

1995

Other Studies

22 other studies available for halothane and Cholestasis

ArticleYear
Effects of liver injury and cholestasis on microsomal enzyme activities and metabolism of halothane, enflurane and methoxyflurane in vivo in rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 1981, Volume: 11, Issue:5

    Topics: Anesthetics; Animals; Carbon Tetrachloride Poisoning; Cholestasis; Enflurane; Half-Life; Halothane;

1981
Impaired bile flow and disordered hepatic calcium homeostasis are early features of halothane-induced liver injury in guinea pigs.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:1

    Topics: Animals; Bile; Bile Acids and Salts; Biological Transport; Calcium; Cell Membrane Permeability; Chol

1996
Leukocyte migration inhibition in halothane-induced hepatitis.
    Clinical immunology and immunopathology, 1979, Volume: 14, Issue:1

    Topics: Adult; Aged; Cell Migration Inhibition; Chemical and Drug Induced Liver Injury; Cholelithiasis; Chol

1979
Hepatic reactions to drugs.
    Gut, 1979, Volume: 20, Issue:7

    Topics: Acetaminophen; Adenoma; Adult; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur

1979
[Postoperative medical jaundice (author's transl)].
    Annales de chirurgie, 1978, Volume: 32, Issue:2

    Topics: Bacterial Infections; Chemical and Drug Induced Liver Injury; Cholestasis; Halothane; Hemolysis; Hum

1978
[Postoperative icterus].
    Der Internist, 1976, Volume: 17, Issue:6

    Topics: Blood; Cholestasis; Diagnosis, Differential; Halothane; Hemolysis; Hemorrhage; Hepatitis; Humans; Hy

1976
Liver disease caused by medicinal agents.
    The Medical clinics of North America, 1975, Volume: 59, Issue:4

    Topics: Adrenal Cortex Hormones; Analgesics; Chemical and Drug Induced Liver Injury; Cholestasis; Contracept

1975
[Rules for the histological evaluation of drug-induced liver lesions].
    Deutsche medizinische Wochenschrift (1946), 1975, Aug-29, Volume: 100, Issue:35

    Topics: Biopsy; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholestasis; Contraceptives, Oral; F

1975
[Postoperative icterus].
    La Nouvelle presse medicale, 1975, May-31, Volume: 4, Issue:22

    Topics: Anesthesia, Inhalation; Bacterial Infections; Chemical and Drug Induced Liver Injury; Cholestasis; H

1975
[Drug-induced liver diseases].
    Gastroenterologische Fortbildungskurse fur die Praxis, 1975, Volume: 5

    Topics: Acetaminophen; Adult; Alcoholism; Azathioprine; Bilirubin; Chemical and Drug Induced Liver Injury; C

1975
[Is MAC effected by liver dysfunction?--Bilirubin and MAC].
    Masui. The Japanese journal of anesthesiology, 1990, Volume: 39, Issue:1

    Topics: Anesthesia, Inhalation; Animals; Bilirubin; Cholestasis; Dogs; Halothane

1990
Anesthesia and pressor responsiveness in chronic bile-duct-ligated dogs.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:4

    Topics: Anesthesia; Angiotensin II; Animals; Bile Ducts; Blood Pressure; Cholestasis; Dogs; Fentanyl; Haloth

1990
[Morphology and etiology of halothane-induced liver lesions (author's transl)].
    Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1972, Volume: 56

    Topics: Adult; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Child; Cholestasis; Fatty Liv

1972
Guidelines for diagnosis of therapeutic drug-induced liver injury in liver biopsies.
    Lancet (London, England), 1974, May-04, Volume: 1, Issue:7862

    Topics: Anabolic Agents; Biopsy; Cathartics; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholest

1974
Peritoneoscopy during hepatic coma.
    Acta gastro-enterologica Belgica, 1973, Volume: 36, Issue:12

    Topics: Adolescent; Adult; Aged; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Haloth

1973
[Sedatives and liver diseases].
    Minerva medica, 1973, Volume: 64, Issue:49

    Topics: Barbiturates; Chemical and Drug Induced Liver Injury; Cholestasis; Halothane; Humans; Hypnotics and

1973
[Drug-induced hepatopathies].
    Polskie Archiwum Medycyny Wewnetrznej, 1974, Volume: 51, Issue:5

    Topics: Adult; Age Factors; Bilirubin; Cell Membrane; Chemical and Drug Induced Liver Injury; Cholestasis; D

1974
Liver disease in pregnancy.
    The Medical clinics of North America, 1974, Volume: 58, Issue:4

    Topics: Acute Kidney Injury; Chemical and Drug Induced Liver Injury; Cholestasis; Contraceptives, Oral; Fatt

1974
Hepatitis and hepatic failure in pregnancy.
    Obstetrics and gynecology, 1972, Volume: 40, Issue:4

    Topics: Cholestasis; Fatty Liver; Female; Halothane; Hepatitis; Hepatitis A; Hepatitis B; Hepatitis B Antige

1972
Hepatic necrosis associated with halothane anesthesia.
    The American journal of medicine, 1969, Volume: 47, Issue:5

    Topics: Anesthesia; Autopsy; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis; Collagen; Connecti

1969
The effect of halothane in the rat with experimental obstructive juandice.
    Acta physiologica Academiae Scientiarum Hungaricae, 1968, Volume: 34, Issue:1

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bilirubin; Blood Proteins; Cholestasis; Female;

1968
[Benign postoperative intrahepatic cholestasis].
    Der Anaesthesist, 1966, Volume: 15, Issue:10

    Topics: Anesthesia, Inhalation; Blood Transfusion; Cholestasis; Halothane; Humans; Neuroleptanalgesia; Posto

1966