halothane has been researched along with Brain Ischemia in 58 studies
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cerebral blood flow (CBF) and blood-brain barrier (BBB) permeability by arterial spin labeling (ASL)- and dynamic contrast enhanced (DCE)-magnetic resonance imaging (MRI), respectively were repeatedly measured under either halothane (N = 5) or isoflurane (N = 5) anesthesia in a rat stroke model of embolic occlusion of middle cerebral artery (MCA)." | 7.80 | Rate and extent of leakage of a magnetic resonance contrast agent tend to be lower under isoflurane anesthesia in comparison to halothane in a rat model of embolic stroke. ( Alarcon, W; Bezerra, FJ; Brown, M; Karki, K; Keenan, KA; Knight, RA; Nagaraja, TN, 2014) |
| " This study was designed to quantitatively evaluate the neuroprotective effects of thiopental, propofol, and halothane on brain ischemia by determining P50, ischemic time necessary for causing 50% neuronal damage." | 7.74 | Quantitative evaluation of the neuroprotective effects of thiopental sodium, propofol, and halothane on brain ischemia in the gerbil: effects of the anesthetics on ischemic depolarization and extracellular glutamate concentration. ( Aoe, H; Kobayashi, M; Morita, K; Takata, K; Takeda, Y; Taninishi, H, 2007) |
| "Desflurane shows better preservation of mitochondrial function at 4 h after cerebral ischemia reperfusion injury, indicated by inhibition of mitochondrial swelling, increase of membrane potential, and improvement of functions of mitochondria respiratory complexes I + III and IV when compared with halothane." | 7.74 | Desflurane affords greater protection than halothane in the function of mitochondria against forebrain ischemia reperfusion injury in rats. ( Cui, X; Ding, W; Li, W; Wei, X; Zhang, B; Zhou, H, 2008) |
| " Cerebral ischemia profoundly alters glutamatergic neurotransmission and thus may also alter halothane MAC." | 7.69 | Minimum alveolar concentration for halothane in the rat is resistant to effects of forebrain ischemia and reperfusion. ( Dexter, F; Ludwig, PA; McFarlane, C; Warner, DS, 1994) |
| " We evaluated whether the effect of sevoflurane is similar to that of isoflurane or halothane on brain energy metabolism after cerebral ischemia followed by reperfusion using 31P-magnetic resonance spectroscopy." | 7.69 | The effects of sevoflurane on recovery of brain energy metabolism after cerebral ischemia in the rat: a comparison with isoflurane and halothane. ( Fujise, Y; Ikeda, K; Moriwaki, G; Nakajima, Y, 1997) |
| " To determine the degree of anesthetic effect on the collapse of cytoskeletal proteins, we compared the effect of three inhalation anesthetics; isoflurane, halothane, and nitrous oxide (N2O), on MAP2 degradation during 20 min of forebrain ischemia in the rat." | 7.69 | Nitrous oxide attenuates the protective effect of isoflurane on microtubule-associated protein2 degradation during forebrain ischemia in the rat. ( Kitani, Y; Sugaya, T, 1997) |
| "In halothane-anesthetized dogs, a decrease in baroreflex sensitivity (BRS) of approximately 20% was observed during the reperfusion period following 5-min global cerebral ischemia." | 7.68 | Difference between halothane and barbiturate anesthesia in the influence of cerebral ischemia on the vagal baroreflex in dogs. ( Kato, H; Kurihara, J; Tomita, H, 1992) |
| "The effect of postischemic halothane anesthesia on locomotor activity and delayed neuronal injury in the hippocampal CA1 sector was examined in gerbils subjected to 5-min forebrain ischemia." | 7.68 | Therapeutic window of halothane anesthesia for reversal of delayed neuronal injury in gerbils: relationship to postischemic motor hyperactivity. ( Bonnekoh, P; Hossmann, KA; Kuroiwa, T, 1991) |
| "Changes in the electrocardiogram following bilateral common carotid arteries ligation was observed during the awake state and pentobarbital anesthesia; and the influences of cerebral ischemia, pentobarbital or halothane anesthesia on the cardiotoxicity induced by continuous infusion of ouabain were also studied in Mongolian gerbils." | 7.68 | [Experimental study on arrhythmias induced by cerebral ischemia and ouabain in Mongolian gerbils]. ( Maruyama, Y; Nakamura, T, 1991) |
| "Using rats in which incomplete cerebral ischemia was induced, the authors evaluated the effects of halothane (H) and isoflurane (I) on neurologic outcome compared to nitrous oxide (N2O) controls." | 7.67 | Neurologic outcome in rats following incomplete cerebral ischemia during halothane, isoflurane, or N2O. ( Albrecht, RF; Baughman, VL; Hoffman, WE; Miletich, DJ; Thomas, C, 1988) |
| "Fentanyl citrate has properties, including agonism of the mu-opioid receptor and proconvulsant activity, that theoretically could pose adverse effects in ischemic brain." | 5.30 | High-dose fentanyl does not adversely affect outcome from forebrain ischemia in the rat. ( Bart, RD; Dexter, F; Morimoto, Y; Pearlstein, RD; Warner, DS, 1997) |
| "Cerebral blood flow (CBF) and blood-brain barrier (BBB) permeability by arterial spin labeling (ASL)- and dynamic contrast enhanced (DCE)-magnetic resonance imaging (MRI), respectively were repeatedly measured under either halothane (N = 5) or isoflurane (N = 5) anesthesia in a rat stroke model of embolic occlusion of middle cerebral artery (MCA)." | 3.80 | Rate and extent of leakage of a magnetic resonance contrast agent tend to be lower under isoflurane anesthesia in comparison to halothane in a rat model of embolic stroke. ( Alarcon, W; Bezerra, FJ; Brown, M; Karki, K; Keenan, KA; Knight, RA; Nagaraja, TN, 2014) |
| " This study was designed to quantitatively evaluate the neuroprotective effects of thiopental, propofol, and halothane on brain ischemia by determining P50, ischemic time necessary for causing 50% neuronal damage." | 3.74 | Quantitative evaluation of the neuroprotective effects of thiopental sodium, propofol, and halothane on brain ischemia in the gerbil: effects of the anesthetics on ischemic depolarization and extracellular glutamate concentration. ( Aoe, H; Kobayashi, M; Morita, K; Takata, K; Takeda, Y; Taninishi, H, 2007) |
| "Desflurane shows better preservation of mitochondrial function at 4 h after cerebral ischemia reperfusion injury, indicated by inhibition of mitochondrial swelling, increase of membrane potential, and improvement of functions of mitochondria respiratory complexes I + III and IV when compared with halothane." | 3.74 | Desflurane affords greater protection than halothane in the function of mitochondria against forebrain ischemia reperfusion injury in rats. ( Cui, X; Ding, W; Li, W; Wei, X; Zhang, B; Zhou, H, 2008) |
| " Although anesthesia by halothane via face-mask allowed better control of depth of anesthesia than chloral hydrate, we have found this method to be unsatisfactory due to insufficient control of ventilation and waste of anesthetic gases." | 3.71 | Anesthetic methods in rats determine outcome after experimental focal cerebral ischemia: mechanical ventilation is required to obtain controlled experimental conditions. ( Baethmann, A; Schmid-Elsaesser, R; Zausinger, S, 2002) |
| "Previous work has demonstrated that rats anesthetized with halothane during focal cerebral ischemia have better histologic and neurologic outcome than do rats undergoing the same insult when awake." | 3.69 | Halothane reduces focal ischemic injury in the rat when brain temperature is controlled. ( Brinkhous, AD; Ludwig, PS; Pearlstein, R; Warner, DS, 1995) |
| " In order to select a suitable volatile anaesthetic from the standpoint of cytoskeletal protein breakdown during cerebral ischemia, we compared the effect of isoflurane, halothane and sevoflurane on MAP 2 degradation during 20 min of forebrain ischemia in the rat." | 3.69 | [Effects of volatile anesthetics on microtubule-associated protein 2 degradation during forebrain ischemia in the rat]. ( Fujita, T; Kitani, Y; Morita, T; Saito, S; Sugaya, T; Uehara, K, 1994) |
| " Cerebral ischemia profoundly alters glutamatergic neurotransmission and thus may also alter halothane MAC." | 3.69 | Minimum alveolar concentration for halothane in the rat is resistant to effects of forebrain ischemia and reperfusion. ( Dexter, F; Ludwig, PA; McFarlane, C; Warner, DS, 1994) |
| "The early effects of 5 or 10 min global cerebral ischemia, sham operation and halothane anesthesia were evaluated in Mongolian gerbils by means of electroencephalography (EEG), neurological examination and passive avoidance training." | 3.69 | Response variability to ischemic injury in the Mongolian gerbil: an electroencephalographic and behavioral study. ( Adami, M; Ambrosini, MV; Bruschelli, G; de Rino, F; Gambelunghe, C; Mariucci, G, 1996) |
| " We evaluated whether the effect of sevoflurane is similar to that of isoflurane or halothane on brain energy metabolism after cerebral ischemia followed by reperfusion using 31P-magnetic resonance spectroscopy." | 3.69 | The effects of sevoflurane on recovery of brain energy metabolism after cerebral ischemia in the rat: a comparison with isoflurane and halothane. ( Fujise, Y; Ikeda, K; Moriwaki, G; Nakajima, Y, 1997) |
| " To determine the degree of anesthetic effect on the collapse of cytoskeletal proteins, we compared the effect of three inhalation anesthetics; isoflurane, halothane, and nitrous oxide (N2O), on MAP2 degradation during 20 min of forebrain ischemia in the rat." | 3.69 | Nitrous oxide attenuates the protective effect of isoflurane on microtubule-associated protein2 degradation during forebrain ischemia in the rat. ( Kitani, Y; Sugaya, T, 1997) |
| "In halothane-anesthetized dogs, a decrease in baroreflex sensitivity (BRS) of approximately 20% was observed during the reperfusion period following 5-min global cerebral ischemia." | 3.68 | Difference between halothane and barbiturate anesthesia in the influence of cerebral ischemia on the vagal baroreflex in dogs. ( Kato, H; Kurihara, J; Tomita, H, 1992) |
| "The effect of postischemic halothane anesthesia on locomotor activity and delayed neuronal injury in the hippocampal CA1 sector was examined in gerbils subjected to 5-min forebrain ischemia." | 3.68 | Therapeutic window of halothane anesthesia for reversal of delayed neuronal injury in gerbils: relationship to postischemic motor hyperactivity. ( Bonnekoh, P; Hossmann, KA; Kuroiwa, T, 1991) |
| "Changes in the electrocardiogram following bilateral common carotid arteries ligation was observed during the awake state and pentobarbital anesthesia; and the influences of cerebral ischemia, pentobarbital or halothane anesthesia on the cardiotoxicity induced by continuous infusion of ouabain were also studied in Mongolian gerbils." | 3.68 | [Experimental study on arrhythmias induced by cerebral ischemia and ouabain in Mongolian gerbils]. ( Maruyama, Y; Nakamura, T, 1991) |
| "Using rats in which incomplete cerebral ischemia was induced, the authors evaluated the effects of halothane (H) and isoflurane (I) on neurologic outcome compared to nitrous oxide (N2O) controls." | 3.67 | Neurologic outcome in rats following incomplete cerebral ischemia during halothane, isoflurane, or N2O. ( Albrecht, RF; Baughman, VL; Hoffman, WE; Miletich, DJ; Thomas, C, 1988) |
| "Forebrain ischemia was performed for 3, 5, or 7 min, and direct-current potential in the hippocampal CA1 region was recorded." | 1.35 | Effect of nitrous oxide on neuronal damage and extracellular glutamate concentration as a function of mild, moderate, or severe ischemia in halothane-anesthetized gerbils. ( Arai, M; Kobayashi, M; Morita, K; Sasaki, T; Takeda, Y; Taninishi, H, 2008) |
| "In the short-duration groups, cerebral infarct volumes were not significantly different between anaesthetics (short-duration halothane: 288 (61) mm(3), mean (SD); short-duration desflurane: 269 (71) mm(3), P>0." | 1.32 | Desflurane affords greater protection than halothane against focal cerebral ischaemia in the rat. ( Ducouret, P; Gérard, JL; Haelewyn, B; Hanouz, JL; MacKenzie, ET; Roussel, S; Yvon, A, 2003) |
| "Halothane-pretreated animals were subjected to MCAO 24 hours after AP." | 1.31 | Tolerance against ischemic neuronal injury can be induced by volatile anesthetics and is inducible NO synthase dependent. ( Dirnagl, U; Fütterer, C; Isaev, NK; Kapinya, KJ; Löwl, D; Maurer, M; Waschke, KF, 2002) |
| "Halothane is a strong inhibitor of potassium evoked spreading depression (SD) in cats." | 1.30 | Reduction of infarct volume by halothane: effect on cerebral blood flow or perifocal spreading depression-like depolarizations. ( Fujita, T; Graf, R; Heiss, WD; Hübel, K; Rosner, G; Saito, R, 1997) |
| "Fentanyl citrate has properties, including agonism of the mu-opioid receptor and proconvulsant activity, that theoretically could pose adverse effects in ischemic brain." | 1.30 | High-dose fentanyl does not adversely affect outcome from forebrain ischemia in the rat. ( Bart, RD; Dexter, F; Morimoto, Y; Pearlstein, RD; Warner, DS, 1997) |
| "The control EEG 1-h after complete cerebral ischemia, but immediately before administering the drug treatments, consisted predominantly of a delta rhythm, denoting cerebral dysfunction." | 1.28 | The effects of intravenous succinylcholine on cerebral function and muscle afferent activity following complete ischemia in halothane-anesthetized dogs. ( Iaizzo, PA; Lanier, WL; Milde, JH, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (17.24) | 18.7374 |
| 1990's | 32 (55.17) | 18.2507 |
| 2000's | 12 (20.69) | 29.6817 |
| 2010's | 2 (3.45) | 24.3611 |
| 2020's | 2 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Keshavarz, S | 1 |
| Nemati, M | 1 |
| Saied Salehi, M | 1 |
| Naseh, M | 1 |
| Chen, G | 1 |
| Kamat, PK | 1 |
| Ahmad, AS | 1 |
| Doré, S | 1 |
| Bezerra, FJ | 1 |
| Brown, M | 1 |
| Alarcon, W | 1 |
| Karki, K | 1 |
| Knight, RA | 1 |
| Keenan, KA | 1 |
| Nagaraja, TN | 1 |
| Lückl, J | 1 |
| Dreier, JP | 1 |
| Szabados, T | 1 |
| Wiesenthal, D | 1 |
| Bari, F | 1 |
| Greenberg, JH | 2 |
| Miura, Y | 1 |
| Amagasa, S | 1 |
| Haelewyn, B | 1 |
| Yvon, A | 1 |
| Hanouz, JL | 1 |
| MacKenzie, ET | 1 |
| Ducouret, P | 1 |
| Gérard, JL | 1 |
| Roussel, S | 1 |
| Riek-Burchardt, M | 1 |
| Henrich-Noack, P | 2 |
| Metz, GA | 1 |
| Reymann, KG | 2 |
| Bendel, O | 1 |
| Alkass, K | 1 |
| Bueters, T | 1 |
| von Euler, M | 1 |
| von Euler, G | 1 |
| Baldauf, K | 1 |
| Kobayashi, M | 2 |
| Takeda, Y | 2 |
| Taninishi, H | 2 |
| Takata, K | 1 |
| Aoe, H | 1 |
| Morita, K | 2 |
| Zhang, B | 1 |
| Wei, X | 1 |
| Cui, X | 1 |
| Zhou, H | 1 |
| Ding, W | 1 |
| Li, W | 1 |
| Sasaki, T | 1 |
| Arai, M | 1 |
| McMeniman, WJ | 1 |
| Kam, PC | 1 |
| Messick, JM | 1 |
| Sharbrough, F | 1 |
| Sundt, T | 1 |
| Nemoto, EM | 1 |
| Shiu, GK | 1 |
| Bleyaert, AL | 1 |
| Xu, ZC | 1 |
| Warner, DS | 10 |
| Ludwig, PS | 1 |
| Pearlstein, R | 1 |
| Brinkhous, AD | 1 |
| Sugaya, T | 3 |
| Kitani, Y | 3 |
| Saito, S | 1 |
| Uehara, K | 1 |
| Morita, T | 1 |
| Fujita, T | 2 |
| Verhaegen, M | 1 |
| Todd, MM | 6 |
| McFarlane, C | 2 |
| Dexter, F | 2 |
| Ludwig, PA | 1 |
| Montalbetti, L | 1 |
| Bo, P | 1 |
| Romani, A | 1 |
| Ciuffreda, A | 1 |
| Savoldi, F | 1 |
| Drummond, JC | 4 |
| Ludwig, P | 1 |
| McAllister, AM | 1 |
| Hoffman, WE | 3 |
| Lingamneni, P | 1 |
| Minshall, R | 1 |
| Miletich, DJ | 2 |
| Albrecht, RF | 3 |
| Thomas, C | 2 |
| Cole, DJ | 3 |
| Patel, PM | 2 |
| Reynolds, LW | 1 |
| Gambelunghe, C | 1 |
| Mariucci, G | 1 |
| Bruschelli, G | 1 |
| Adami, M | 1 |
| de Rino, F | 1 |
| Ambrosini, MV | 1 |
| McKinley, BA | 1 |
| Morris, WP | 1 |
| Parmley, CL | 1 |
| Butler, BD | 1 |
| Saito, R | 1 |
| Graf, R | 1 |
| Hübel, K | 1 |
| Rosner, G | 1 |
| Heiss, WD | 1 |
| Nakajima, Y | 1 |
| Moriwaki, G | 1 |
| Ikeda, K | 1 |
| Fujise, Y | 1 |
| Morimoto, Y | 2 |
| Bart, RD | 1 |
| Pearlstein, RD | 2 |
| Racay, P | 1 |
| Kaplán, P | 1 |
| Lehotský, J | 1 |
| Nellgård, B | 1 |
| Mackensen, GB | 1 |
| Pineda, J | 1 |
| Wellons, JC | 1 |
| Zausinger, S | 1 |
| Baethmann, A | 1 |
| Schmid-Elsaesser, R | 1 |
| Kapinya, KJ | 1 |
| Löwl, D | 1 |
| Fütterer, C | 1 |
| Maurer, M | 1 |
| Waschke, KF | 1 |
| Isaev, NK | 1 |
| Dirnagl, U | 1 |
| Sundt, TM | 2 |
| Anderson, RE | 1 |
| Michenfelder, JD | 2 |
| Kurihara, J | 1 |
| Tomita, H | 1 |
| Kato, H | 1 |
| Holder, DS | 1 |
| Verhaegen, MJ | 1 |
| Ridenour, TR | 1 |
| Gionet, TX | 1 |
| Ruta, TS | 1 |
| Sano, T | 1 |
| Grafe, MR | 1 |
| Watson, JC | 1 |
| Kuroiwa, T | 3 |
| Bonnekoh, P | 3 |
| Hossmann, KA | 3 |
| Nakamura, T | 1 |
| Maruyama, Y | 1 |
| Zhou, JG | 1 |
| Ramani, R | 1 |
| Lanier, WL | 1 |
| Iaizzo, PA | 1 |
| Milde, JH | 1 |
| Cahn, R | 1 |
| Dupont, JM | 1 |
| Borzeix, MG | 1 |
| Cahn, J | 1 |
| Silbert, BS | 1 |
| Koumoundouros, E | 1 |
| Davies, MJ | 1 |
| Cronin, KD | 1 |
| Freund, TF | 1 |
| Buzsáki, G | 1 |
| Prohaska, OJ | 1 |
| Leon, A | 1 |
| Somogyi, P | 1 |
| Urbanics, R | 1 |
| Toffano, G | 1 |
| Reivich, M | 1 |
| Baughman, VL | 1 |
| Fode, N | 1 |
| Sharbrough, FW | 1 |
| González-Méndez, R | 1 |
| McNeill, A | 1 |
| Gregory, GA | 1 |
| Wall, SD | 1 |
| Gooding, CA | 1 |
| Litt, L | 1 |
| James, TL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Inhalatorial Sedation in Patient With SAH Versus Conventional Intravenous Sedation (GAS-SAH)[NCT00830843] | Phase 4 | 13 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for halothane and Brain Ischemia
| Article | Year |
|---|---|
[Perioperative cerebral ischemia and the possibility of neuroprotection by inhalational anesthetics].
Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Brain; Brain Ischemia; Coronary Artery Bypass | 2003 |
Cerebral perfusion and cerebral protection during carotid endarterectomy.
Topics: Anticoagulants; Arteriovenous Shunt, Surgical; Barbiturates; Brain Ischemia; Carbon Dioxide; Carotid | 1983 |
56 other studies available for halothane and Brain Ischemia
| Article | Year |
|---|---|
The impact of anesthetic drugs on hemodynamic parameters and neurological outcomes following temporal middle cerebral artery occlusion in rats.
Topics: Anesthetics; Animals; Brain Ischemia; Chloral Hydrate; Halothane; Hemodynamics; Infarction, Middle C | 2023 |
Distinctive effect of anesthetics on the effect of limb remote ischemic postconditioning following ischemic stroke.
Topics: Analgesics; Anesthetics; Animals; Brain Infarction; Brain Ischemia; Extremities; Halothane; Infarcti | 2020 |
Rate and extent of leakage of a magnetic resonance contrast agent tend to be lower under isoflurane anesthesia in comparison to halothane in a rat model of embolic stroke.
Topics: Anesthetics, Inhalation; Animals; Blood-Brain Barrier; Brain Ischemia; Cerebrovascular Circulation; | 2014 |
Peri-infarct flow transients predict outcome in rat focal brain ischemia.
Topics: Anesthesia; Anesthesia, Inhalation; Animals; Basal Ganglia; Blood Pressure; Brain Ischemia; Carbon D | 2012 |
Desflurane affords greater protection than halothane against focal cerebral ischaemia in the rat.
Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Blood Pressure; Brain Ischemia; Carbon Dioxi | 2003 |
Detection of chronic sensorimotor impairments in the ladder rung walking task in rats with endothelin-1-induced mild focal ischemia.
Topics: Anesthetics, Inhalation; Animals; Behavior, Animal; Brain Infarction; Brain Ischemia; Chronic Diseas | 2004 |
Reproducible loss of CA1 neurons following carotid artery occlusion combined with halothane-induced hypotension.
Topics: Animals; Brain Ischemia; Carotid Artery, Common; Carotid Stenosis; Cell Count; Halothane; Hypotensio | 2005 |
Detrimental effects of halothane narcosis on damage after endothelin-1-induced MCAO.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Cerebral Infarction; Endothelin-1; Endothelium, Va | 2007 |
Quantitative evaluation of the neuroprotective effects of thiopental sodium, propofol, and halothane on brain ischemia in the gerbil: effects of the anesthetics on ischemic depolarization and extracellular glutamate concentration.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Brain; Brain Ischemia; Electroencephalog | 2007 |
Desflurane affords greater protection than halothane in the function of mitochondria against forebrain ischemia reperfusion injury in rats.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Desfl | 2008 |
Effect of nitrous oxide on neuronal damage and extracellular glutamate concentration as a function of mild, moderate, or severe ischemia in halothane-anesthetized gerbils.
Topics: Anesthetics, Inhalation; Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Disease Models | 2008 |
Selective shunting on the basis of EEG and regional CBF monitoring during carotid endarterectomy.
Topics: Anesthesia, Inhalation; Brain Ischemia; Carbon Dioxide; Carotid Arteries; Carotid Artery Diseases; C | 1984 |
Efficacy of therapies and attenuation of brain free fatty acid liberation during global ischemia.
Topics: Animals; Brain; Brain Ischemia; Etomidate; Fatty Acids, Nonesterified; Female; Halothane; Hypothermi | 1981 |
Neurophysiological changes of spiny neurons in rat neostriatum after transient forebrain ischemia: an in vivo intracellular recording and staining study.
Topics: Animals; Brain Ischemia; Electrophysiology; Halothane; Male; Membrane Potentials; Neostriatum; Neuro | 1995 |
Halothane reduces focal ischemic injury in the rat when brain temperature is controlled.
Topics: Animals; Body Temperature; Brain; Brain Ischemia; Halothane; Male; Rats; Rats, Wistar | 1995 |
[Effects of volatile anesthetics on microtubule-associated protein 2 degradation during forebrain ischemia in the rat].
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Electroencephalography; Ethers; Halothane; Isoflur | 1994 |
Ischemic depolarization during halothane-nitrous oxide and isoflurane-nitrous oxide anesthesia. An examination of cerebral blood flow threshold and times to depolarization.
Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Brain; Brain Ischemia; Cerebrovascular Circulation; | 1994 |
Minimum alveolar concentration for halothane in the rat is resistant to effects of forebrain ischemia and reperfusion.
Topics: Animals; Brain Ischemia; Electroencephalography; Glutamic Acid; Halothane; Male; Prosencephalon; Pul | 1994 |
Isoflurane reduces microtubule-associated protein 2 degradation compared with halothane during forebrain ischaemia in the rat.
Topics: Animals; Brain Ischemia; Halothane; Isoflurane; Male; Microtubule-Associated Proteins; Prosencephalo | 1993 |
Neurophysiological parameters during halothane anaesthesia in experimental models of cerebral ischemia.
Topics: Anesthesia, Inhalation; Animal Rights; Animals; Brain Ischemia; Electroencephalography; Evoked Poten | 1993 |
Brain protection during anesthesia. A reader's guide.
Topics: Anesthetics; Animals; Brain Injuries; Brain Ischemia; Ethers; Halothane; Humans; Hypothermia, Induce | 1993 |
Sevoflurane and halothane reduce focal ischemic brain damage in the rat. Possible influence on thermoregulation.
Topics: Anesthesia, Inhalation; Anesthetics; Animals; Body Temperature Regulation; Brain Ischemia; Ethers; H | 1993 |
Brain alpha 2-adrenergic receptor binding during incomplete cerebral ischemia in the rat.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Blood Pressure; Brain; Brain Ischemia; Car | 1993 |
The effect of halothane and isoflurane on neurologic outcome following incomplete cerebral ischemia in the rat.
Topics: Anesthesia, Inhalation; Animals; Brain Ischemia; Catecholamines; Fentanyl; Halothane; Isoflurane; Ma | 1993 |
Focal cerebral ischemia during anesthesia with etomidate, isoflurane, or thiopental: a comparison of the extent of cerebral injury.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Brain; Brain Damage | 1995 |
Response variability to ischemic injury in the Mongolian gerbil: an electroencephalographic and behavioral study.
Topics: Anesthesia, Inhalation; Animals; Behavior, Animal; Brain Ischemia; Carotid Arteries; Coma; Constrict | 1996 |
Brain parenchyma PO2, PCO2, and pH during and after hypoxic, ischemic brain insult in dogs.
Topics: Anesthesia; Animals; Blood Gas Analysis; Brain Chemistry; Brain Ischemia; Carbon Dioxide; Cerebrovas | 1996 |
Reduction of infarct volume by halothane: effect on cerebral blood flow or perifocal spreading depression-like depolarizations.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Cats; Cerebral Infarction; Cerebrovascular Circula | 1997 |
The effects of sevoflurane on recovery of brain energy metabolism after cerebral ischemia in the rat: a comparison with isoflurane and halothane.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Brain; Brain Ischemia; Energy Metabolism; | 1997 |
Nitrous oxide attenuates the protective effect of isoflurane on microtubule-associated protein2 degradation during forebrain ischemia in the rat.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Halothane; Isoflurane; Male; Microtubule-Associate | 1997 |
High-dose fentanyl does not adversely affect outcome from forebrain ischemia in the rat.
Topics: Anesthesia; Anesthetics, General; Anesthetics, Intravenous; Animals; Blood Pressure; Body Temperatur | 1997 |
Ischemia-induced inhibition of active calcium transport into gerbil brain microsomes: effect of anesthetics and models of ischemia.
Topics: Anesthetics, Inhalation; Animals; Brain; Brain Ischemia; Calcium; Calcium-Transporting ATPases; Dise | 2000 |
Anesthetic effects on cerebral metabolic rate predict histologic outcome from near-complete forebrain ischemia in the rat.
Topics: Anesthetics, Inhalation; Animals; Body Weight; Brain; Brain Ischemia; Halothane; Hemodynamics; Isofl | 2000 |
Anesthetic methods in rats determine outcome after experimental focal cerebral ischemia: mechanical ventilation is required to obtain controlled experimental conditions.
Topics: Acidosis, Respiratory; Anesthesia; Anesthetics; Animals; Brain; Brain Ischemia; Cerebral Infarction; | 2002 |
Tolerance against ischemic neuronal injury can be induced by volatile anesthetics and is inducible NO synthase dependent.
Topics: Anesthetics, Inhalation; Animals; Body Temperature; Brain; Brain Infarction; Brain Ischemia; Cells, | 2002 |
Intracellular redox states under halothane and barbiturate anesthesia in normal, ischemic, and anoxic monkey brain.
Topics: Animals; Brain; Brain Ischemia; Carbon Dioxide; Cerebrovascular Circulation; Halothane; Haplorhini; | 1979 |
Difference between halothane and barbiturate anesthesia in the influence of cerebral ischemia on the vagal baroreflex in dogs.
Topics: Anesthesia; Animals; Barbiturates; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Dogs | 1992 |
Effects of urethane, alphaxolone/alphadolone, or halothane with or without neuromuscular blockade on survival during repeated episodes of global cerebral ischaemia in the rat.
Topics: Anesthetics; Animals; Arterial Occlusive Diseases; Brain Ischemia; Carotid Artery Diseases; Disease | 1992 |
A comparison of cerebral ischemic flow thresholds during halothane/N2O and isoflurane/N2O anesthesia in rats.
Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Brain; Brain Ischemia; Cerebrovascular Circulation; | 1992 |
Comparative effects of propofol and halothane on outcome from temporary middle cerebral artery occlusion in the rat.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Blood Pressure; Brain; Brain Ischemia; Hal | 1992 |
A comparison of the area of histochemical dysfunction after focal cerebral ischaemia during anaesthesia with isoflurane and halothane in the rat.
Topics: Anesthesia, Inhalation; Animals; Brain; Brain Ischemia; Halothane; Isoflurane; Male; Rats; Rats, Inb | 1991 |
A comfortable hypothesis reevaluated. Cerebral metabolic depression and brain protection during ischemia.
Topics: Animals; Brain; Brain Ischemia; Depression, Chemical; Dogs; Halothane; Hypothermia, Induced; Isoflur | 1992 |
A comparison of the cerebral protective effects of isoflurane and mild hypothermia in a model of incomplete forebrain ischemia in the rat.
Topics: Animals; Brain Ischemia; Depression, Chemical; Halothane; Hypothermia, Induced; Isoflurane; Male; Pr | 1992 |
Therapeutic window of halothane anesthesia for reversal of delayed neuronal injury in gerbils: relationship to postischemic motor hyperactivity.
Topics: Anesthesia; Animals; Body Temperature; Brain Ischemia; Cell Death; Cerebrovascular Circulation; Fema | 1991 |
[Experimental study on arrhythmias induced by cerebral ischemia and ouabain in Mongolian gerbils].
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Blood Pressure; Brain; Brain Ischemia; Electrocardiograph | 1991 |
Reversible focal ischemia in the rat: effects of halothane, isoflurane, and methohexital anesthesia.
Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Halothane; Isoflurane; Male; Methohexit | 1991 |
Postischemic halothane anesthesia and motor hyperactivity in gerbil.
Topics: Anesthesia; Animals; Brain Ischemia; Gerbillinae; Halothane; Hippocampus; Hyperkinesis | 1990 |
Prevention of postischemic hyperthermia prevents ischemic injury of CA1 neurons in gerbils.
Topics: Anesthesia; Animals; Body Temperature; Brain Diseases; Brain Ischemia; Cell Survival; Female; Fever; | 1990 |
The effects of intravenous succinylcholine on cerebral function and muscle afferent activity following complete ischemia in halothane-anesthetized dogs.
Topics: Anesthesia, Inhalation; Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Dogs; Electroen | 1990 |
Effect of halothane on ischemic brain edema.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Gerbillinae; Halothane; Reperfusion | 1990 |
The use of aperiodic analysis of the EEG during carotid artery surgery.
Topics: Aged; Anesthesia, General; Brain Ischemia; Carotid Arteries; Carotid Artery Diseases; Electroencepha | 1989 |
Simultaneous recording of local electrical activity, partial oxygen tension and temperature in the rat hippocampus with a chamber-type microelectrode. Effects of anaesthesia, ischemia and epilepsy.
Topics: Action Potentials; Anesthesia; Animals; Body Temperature Regulation; Brain Ischemia; Epilepsy; Halot | 1989 |
Effect of GM1 ganglioside after focal cerebral ischemia in halothane-anesthetized cats.
Topics: Anesthesia; Animals; Blood Glucose; Brain; Brain Ischemia; Cats; Cerebral Arteries; Cerebrovascular | 1989 |
Neurologic outcome in rats following incomplete cerebral ischemia during halothane, isoflurane, or N2O.
Topics: Anesthesia, Inhalation; Animals; Blood Gas Analysis; Blood Pressure; Brain; Brain Ischemia; Cerebrov | 1988 |
Isoflurane when compared to enflurane and halothane decreases the frequency of cerebral ischemia during carotid endarterectomy.
Topics: Anesthesia, Inhalation; Brain Ischemia; Carotid Arteries; Cerebrovascular Circulation; Endarterectom | 1987 |
Effects of hypoxic hypoxia on cerebral phosphate metabolites and pH in the anesthetized infant rabbit.
Topics: Adenosine Triphosphate; Anesthesia; Animals; Animals, Newborn; Brain; Brain Ischemia; Energy Metabol | 1985 |