halothane and Anoxemia studies

Research Excerpts

Excerpt	Relevance	Reference
"To compare the effects of sub-anaesthetic concentrations of propofol and halothane on the respiratory control system, we have studied the acute ventilatory response to isocapnic hypoxia (AHVR) in 12 adults with and without three different concentrations of propofol and halothane."	9.08	Comparison of the effects of sub-hypnotic concentrations of propofol and halothane on the acute ventilatory response to hypoxia. ( Dorrington, KL; Gill, EW; Nagyova, B; Robbins, PA, 1995)
"Our results indicate that halothane caused VE to be less than control levels during acute and sustained hypoxia as well as when sustained hypoxia is replaced by normoxia."	9.07	Influence of a subanesthetic concentration of halothane on the ventilatory response to step changes into and out of sustained isocapnic hypoxia in healthy volunteers. ( Berkenbosch, A; Burm, AG; Dahan, A; DeGoede, J; Olievier, IC; van den Elsen, MJ; van Kleef, JW, 1994)
"We recently reported that volatile anaesthetics directly depress the isolated glomus cell response to hypoxia, halothane more so than sevoflurane, in a manner mimicking the action of these agents on the human hypoxic ventilatory response."	7.76	Differential effects of halothane and isoflurane on carotid body glomus cell intracellular Ca2+ and background K+ channel responses to hypoxia. ( Bayliss, R; Buckler, KJ; Pandit, JJ; Winter, V, 2010)
"Step decreases in end-tidal partial pressure of oxygen using dynamic end-tidal forcing were performed from normoxia to hypoxia (50 mmHg) in 10 healthy volunteers, with end-tidal partial pressure of carbon dioxide held 1-2 mmHg above normal, in six protocols: (1) control conditions (darkened, quiet room, eyes closed) without halothane and (2) with 0."	7.72	Effect of pain and audiovisual stimulation on the depression of acute hypoxic ventilatory response by low-dose halothane in humans. ( Donoghue, S; Moreau, B; Pandit, JJ; Robbins, PA, 2004)
" The purpose of this study was to evaluate the effect of 7 d of hypoxia on the neonatal rat pup and lactating dam without or with acute halothane anesthesia on serum calcium and calciotropic hormones."	7.71	Effect of hypoxia on parathyroid hormone in lactating and neonatal rats: interaction with halothane. ( Raff, H, 2002)
" The present study addressed this hypothesis by quantitative analysis of ventilatory and carotid chemoreceptor responsiveness to hypoxia during induced hypothermia in halothane anesthetized and spontaneously breathing rats."	7.70	Ventilation- and carotid chemoreceptor discharge-response to hypoxia during induced hypothermia in halothane anesthetized rat. ( Fukuda, Y; Maruyama, R, 2000)
"Three protocols were performed to study the effects of halothane anesthesia on the phrenic nerve response to 1 min of isocapnic hypoxia (partial pressure of oxygen [PaO2] at peak hypoxia, 35-38 mmHg) in unpremedicated, anesthetized, paralyzed, vagotomized dogs during constant mechanical ventilation."	7.69	Dose-dependent effects of halothane on the phrenic nerve responses to acute hypoxia in vagotomized dogs. ( Dogas, Z; Hopp, FA; Kampine, JP; Krolo, M; Stuth, EA; Zuperku, EJ, 1997)
"We examined the effect of halothane on phrenic never and carotid sinus discharge during hypoxia in anesthetized kittens."	7.69	The effect of halothane on phrenic and chemoreceptor responses to hypoxia in anesthetized kittens. ( Bennet, L; Hanson, MA; Morray, JP; Nobel, R, 1996)
"The results show depression of the ventilatory responses to hypoxia and hypercapnia during inhalation of subanesthetic concentrations of halothane."	7.69	Effects of subanesthetic halothane on the ventilatory responses to hypercapnia and acute hypoxia in healthy volunteers. ( Berkenbosch, A; Bovill, JG; Dahan, A; DeGoede, J; Olievier, IC; van den Elsen, MJ; van Kleef, JW, 1994)
"We studied the interactions of atelectasis and halothane on hypoxic pulmonary vasoconstriction using an isolated canine lobe."	7.68	Effects of halothane on hypoxic pulmonary vasoconstriction in canine atelectasis. ( Hurst, TS; Johnson, DH; Mayers, I, 1991)
"To examine the effects of halothane on segmental vascular responses to hypoxia, we used cardiopulmonary bypass with venous outflow divided into three compartments (splanchnic, coronary, and "other") in dogs anesthetized with pentobarbital sodium."	7.68	Modifications by halothane of responses to acute hypoxia in systemic vascular capacitance, resistance, and sympathetic nerve activity in dogs. ( Arimura, H; Bosnjak, ZJ; Hoka, S; Kampine, JP, 1991)
"Hypoxia and halothane are both known to have different effects on the release and disposition of norepinephrine at sympathetic nerve terminals during neurotransmission."	7.68	Altered release and metabolism of norepinephrine in superfused canine saphenous veins in the presence of halothane and hypoxia. ( Kamath, GS; Rorie, DK; Tyce, GM, 1993)
"Toxic systemic reactions to bupivacaine usually involve a number of factors, including hypoxia and acidosis."	7.68	Severe hypoxia enhances central nervous system and cardiovascular toxicity of bupivacaine in lightly anesthetized pigs. ( Badgwell, JM; Bessire, A; Dryden, CF; Heavner, JE; Huemer, G; Sanghani, V, 1992)
"Experimental factors implicated in the pathogenesis of halothane hepatotoxicity in the phenobarbital-hypoxia rat model were examined for direct effects on the energy status of isolated rat liver cells in vitro."	7.67	Energy deficits in hepatocytes isolated from phenobarbital-treated or fasted rats and briefly exposed to halothane and hypoxia in vitro. ( Albrecht, RF; Becker, GL; Hensel, P; Holland, AD; Miletich, DJ, 1986)
"To evaluate the effects of succinylcholine on cardiac arrhythmias and serum levels of potassium and catecholamines, dogs with hypoxia alone and with hypoxia and hypercarbia were studied during anesthesia with halothane or enflurane."	7.67	Mechanisms of succinylcholine-induced arrhythmias in hypoxic or hypoxic:hypercarbic dogs. ( Butler, BD; Katz, J; Leiman, BC, 1987)
"Hypoxia, phenobarbital induction, and halothane anesthesia have been implicated in the pathogenesis of hepatotoxicity in the rat model."	7.67	Comparative toxicity of halothane, isoflurane, hypoxia, and phenobarbital induction in monolayer cultures of rat hepatocytes. ( Costa, AK; Heffel, DF; Schieble, TM; Trudell, JR, 1988)
"Halothane hepatotoxicity was observed after exposing hyperthyroid rats to 0."	7.66	Halothane hepatotoxicity in hyperthyroid rats as compared to the phenobarbital-hypoxia model. ( Frühling, A; Siegers, CP; Younes, M, 1983)
"Factors affecting halothane (H) hepatotoxicity were investigated in two animal models: 1) the phenobarbital-hypoxia model, and 2) the triiodothyronine (T3) model; in the latter we previously have shown that centrilobular necrosis occurs in T3 pretreated rats anesthetized with 1% H, in 21% oxygen for 2 h."	7.66	Contrasting effects on halothane hepatotoxicity in the phenobarbital-hypoxia and triiodothyronine model: mechanistic implications. ( Phythyon, JM; Uetrecht, J; Wood, AJ; Wood, M, 1983)
"Halothane is known to inhibit the ventilatory responses to hypoxia and hypercapnia."	7.66	Halothane depresses the response of carotid body chemoreceptors to hypoxia and hypercapnia in the cat. ( Davies, RO; Edwards, MW; Lahiri, S, 1982)
" Studies were performed to determine whether hypoxia, respiratory acidosis or deep halothane anaesthesia modify the cardiovascular effect of vagal stimulation (VS) in dogs."	7.66	Effect of supramaximal vagal stimulation in combination with hypoxia, respiratory acidosis and deep halothane anaesthesia on cardiovascular function in dogs. ( Bastron, RD; Korttila, K, 1982)
"The pulmonary vascular response to alveolar hypoxia with and without halothane exposure was measured in dogs."	7.66	Effect of halothane on the pulmonary vascular response to hypoxia in dogs. ( Fargas-Babjak, A; Forrest, JB, 1979)
"To evaluate the relative importance of halothane metabolism and liver hypoxia in the occurrence of hepatic injury, the injury produced in hypoxic rats exposed to identical MAC hours of halothane but at various concentrations of halothane was compared."	7.66	Hypoxia may be more important than reductive metabolism in halothane-induced hepatic injury. ( Eger, EI; Johnson, BH; Shingu, K, 1982)
"To elucidate the effects of halothane on chemical regulation of ventilation in man, the authors studied the ventilatory responses to isocapnic hypoxia and hyperoxic hypercapnia in 33 human subjects while fully conscious and during sedation or anesthesia with halothane, ."	7.66	Ventilatory responses to hypoxia and hypercapnia during halothane sedation and anesthesia in man. ( Gelb, AW; Knill, RL, 1978)
"The action of halothane on the pulmonary vasoconstrictor response to unilateral alveolar hypoxia was studied in two groups of dogs."	7.66	Preservation of the pulmonary vasoconstrictor response to alveolar hypoxia during the administration of halothane to dogs. ( Arnot, RN; Gibbs, JM; Loh, L; Marin, JB; Obdrzalek, J; Sykes, MK, 1978)
"Exposure of phenobarbital-pretreated male Sprague-Dawley rats to halothane, 1 per cent, for two hours under conditions of hypoxia (FIO2 0."	7.66	An animal model of halothane hepatotoxicity: roles of enzyme induction and hypoxia. ( Brown, BR; McLain, GE; Sipes, IG, 1979)
"When halothane was administered with adequate oxygen the percentage of the cardiac output delivered to the hepatic artery significantly increased but there was no change in absolute blood flow to either the hepatic artery or portal vein."	5.26	Hepatic blood flow in phenobarbital-pretreated rats during halothane anesthesia and hypoxia. ( Daggy, BP; Ross, WT, 1981)
"To compare the effects of sub-anaesthetic concentrations of propofol and halothane on the respiratory control system, we have studied the acute ventilatory response to isocapnic hypoxia (AHVR) in 12 adults with and without three different concentrations of propofol and halothane."	5.08	Comparison of the effects of sub-hypnotic concentrations of propofol and halothane on the acute ventilatory response to hypoxia. ( Dorrington, KL; Gill, EW; Nagyova, B; Robbins, PA, 1995)
"Our results indicate that halothane caused VE to be less than control levels during acute and sustained hypoxia as well as when sustained hypoxia is replaced by normoxia."	5.07	Influence of a subanesthetic concentration of halothane on the ventilatory response to step changes into and out of sustained isocapnic hypoxia in healthy volunteers. ( Berkenbosch, A; Burm, AG; Dahan, A; DeGoede, J; Olievier, IC; van den Elsen, MJ; van Kleef, JW, 1994)
"0 MAC halothane, isoflurane, and sevoflurane on phrenic nerve activity in euoxia (baseline) and during acute normocapnic hypoxia (inspired oxygen fraction 0."	3.76	The acute hypoxic ventilatory response under halothane, isoflurane, and sevoflurane anaesthesia in rats. ( Carev, M; Dogas, Z; Jeroncic, A; Karanovic, N; Karanovic, S; Pecotic, R; Ujevic, A; Valic, M, 2010)
"We recently reported that volatile anaesthetics directly depress the isolated glomus cell response to hypoxia, halothane more so than sevoflurane, in a manner mimicking the action of these agents on the human hypoxic ventilatory response."	3.76	Differential effects of halothane and isoflurane on carotid body glomus cell intracellular Ca2+ and background K+ channel responses to hypoxia. ( Bayliss, R; Buckler, KJ; Pandit, JJ; Winter, V, 2010)
"The liver of all rats given halothane (14% O(2)) had extensive centrilobular necrosis and denaturation."	3.73	Ca2+ cytochemical changes of hepatotoxicity caused by halothane and sevoflurane in enzyme-induced hypoxic rats. ( Li, Q; Liu, ZQ; Yang, LQ; Yu, WF; Zhou, MT, 2005)
"To determine if doxapram stimulates the carotid body through the same mechanism as hypoxia, we compared the effects of doxapram and hypoxia on isolated-perfused carotid bodies in rabbits."	3.73	Doxapram stimulates the carotid body via a different mechanism than hypoxic chemotransduction. ( Kikuchi, K; Nakano, H; Ohsaki, Y; Osanai, S; Takahashi, T, 2005)
" One particular member of the family, TREK-1 (also known as KCNK2), is activated by increasing temperature, membrane stretch and internal acidosis, but is also sensitive to the presence of certain polyunsaturated fatty acids (such as arachidonic acid), neuroprotectants (such as riluzole) and volatile and gaseous general anaesthetics (such as halothane and nitrous oxide)."	3.73	The effects of hypoxia on the modulation of human TREK-1 potassium channels. ( Caley, AJ; Franks, NP; Gruss, M, 2005)
"Step decreases in end-tidal partial pressure of oxygen using dynamic end-tidal forcing were performed from normoxia to hypoxia (50 mmHg) in 10 healthy volunteers, with end-tidal partial pressure of carbon dioxide held 1-2 mmHg above normal, in six protocols: (1) control conditions (darkened, quiet room, eyes closed) without halothane and (2) with 0."	3.72	Effect of pain and audiovisual stimulation on the depression of acute hypoxic ventilatory response by low-dose halothane in humans. ( Donoghue, S; Moreau, B; Pandit, JJ; Robbins, PA, 2004)
" The purpose of this study was to evaluate the effect of 7 d of hypoxia on the neonatal rat pup and lactating dam without or with acute halothane anesthesia on serum calcium and calciotropic hormones."	3.71	Effect of hypoxia on parathyroid hormone in lactating and neonatal rats: interaction with halothane. ( Raff, H, 2002)
" The present study addressed this hypothesis by quantitative analysis of ventilatory and carotid chemoreceptor responsiveness to hypoxia during induced hypothermia in halothane anesthetized and spontaneously breathing rats."	3.70	Ventilation- and carotid chemoreceptor discharge-response to hypoxia during induced hypothermia in halothane anesthetized rat. ( Fukuda, Y; Maruyama, R, 2000)
" We studied 17 nonsedated lambs after inducing a permeability pulmonary edema via intravenous of either oleic acid (8 lambs) or halothane (9 lambs)."	3.69	Active expiratory glottic closure during permeability pulmonary edema in nonsedated lambs. ( Dalle, D; Diaz, V; Kianicka, I; Praud, JP, 1995)
"The results show depression of the ventilatory responses to hypoxia and hypercapnia during inhalation of subanesthetic concentrations of halothane."	3.69	Effects of subanesthetic halothane on the ventilatory responses to hypercapnia and acute hypoxia in healthy volunteers. ( Berkenbosch, A; Bovill, JG; Dahan, A; DeGoede, J; Olievier, IC; van den Elsen, MJ; van Kleef, JW, 1994)
"We examined the effect of halothane on phrenic never and carotid sinus discharge during hypoxia in anesthetized kittens."	3.69	The effect of halothane on phrenic and chemoreceptor responses to hypoxia in anesthetized kittens. ( Bennet, L; Hanson, MA; Morray, JP; Nobel, R, 1996)
"Three protocols were performed to study the effects of halothane anesthesia on the phrenic nerve response to 1 min of isocapnic hypoxia (partial pressure of oxygen [PaO2] at peak hypoxia, 35-38 mmHg) in unpremedicated, anesthetized, paralyzed, vagotomized dogs during constant mechanical ventilation."	3.69	Dose-dependent effects of halothane on the phrenic nerve responses to acute hypoxia in vagotomized dogs. ( Dogas, Z; Hopp, FA; Kampine, JP; Krolo, M; Stuth, EA; Zuperku, EJ, 1997)
"Toxic systemic reactions to bupivacaine usually involve a number of factors, including hypoxia and acidosis."	3.68	Severe hypoxia enhances central nervous system and cardiovascular toxicity of bupivacaine in lightly anesthetized pigs. ( Badgwell, JM; Bessire, A; Dryden, CF; Heavner, JE; Huemer, G; Sanghani, V, 1992)
" Blood gas values were modified by varying the composition of inspired gases: normoxia, hypocapnic hypoxia, hyperoxia, hypercapnia (in this case eight animals were anaesthetized with halothane 1."	3.68	[The measurement of pH and gases in the blood using microanalysis: the effect of storage at 4 degrees C for an hour. A study in the rat]. ( Gaudy, JH; Quignon, M; Sicard, JF, 1992)
"The authors' aim was to examine direct cardiac responses to isoflurane, enflurane and halothane, as altered during mild hypoxia by the substitution of nitrogen (N2) for oxygen (O2), and additionally by the substitution of nitrous oxide (N2O) for N2."	3.68	Comparison of halothane, enflurane, and isoflurane with nitrous oxide on contractility and oxygen supply and demand in isolated hearts. ( Bosnjak, ZJ; Kampine, JP; Marijic, J; Monroe, SM; Stowe, DF, 1991)
"Hypoxia and halothane are both known to have different effects on the release and disposition of norepinephrine at sympathetic nerve terminals during neurotransmission."	3.68	Altered release and metabolism of norepinephrine in superfused canine saphenous veins in the presence of halothane and hypoxia. ( Kamath, GS; Rorie, DK; Tyce, GM, 1993)
"To examine the effects of halothane on segmental vascular responses to hypoxia, we used cardiopulmonary bypass with venous outflow divided into three compartments (splanchnic, coronary, and "other") in dogs anesthetized with pentobarbital sodium."	3.68	Modifications by halothane of responses to acute hypoxia in systemic vascular capacitance, resistance, and sympathetic nerve activity in dogs. ( Arimura, H; Bosnjak, ZJ; Hoka, S; Kampine, JP, 1991)
"We studied the interactions of atelectasis and halothane on hypoxic pulmonary vasoconstriction using an isolated canine lobe."	3.68	Effects of halothane on hypoxic pulmonary vasoconstriction in canine atelectasis. ( Hurst, TS; Johnson, DH; Mayers, I, 1991)
"The authors investigated the effects of halothane (HAL) and isoflurane (ISO) on cardiac depression produced by global hypoxia and the recovery of function following reoxygenation is isolated guinea pig hearts perfused with Krebs' solution at constant pressure."	3.68	Differential protective effects of halothane and isoflurane against hypoxic and reoxygenation injury in the isolated guinea pig heart. ( Bosnjak, ZJ; Kampine, JP; Marijic, J; Stowe, DF; Turner, LA, 1990)
"To evaluate the effects of succinylcholine on cardiac arrhythmias and serum levels of potassium and catecholamines, dogs with hypoxia alone and with hypoxia and hypercarbia were studied during anesthesia with halothane or enflurane."	3.67	Mechanisms of succinylcholine-induced arrhythmias in hypoxic or hypoxic:hypercarbic dogs. ( Butler, BD; Katz, J; Leiman, BC, 1987)
"Hypoxia, phenobarbital induction, and halothane anesthesia have been implicated in the pathogenesis of hepatotoxicity in the rat model."	3.67	Comparative toxicity of halothane, isoflurane, hypoxia, and phenobarbital induction in monolayer cultures of rat hepatocytes. ( Costa, AK; Heffel, DF; Schieble, TM; Trudell, JR, 1988)
"Experimental factors implicated in the pathogenesis of halothane hepatotoxicity in the phenobarbital-hypoxia rat model were examined for direct effects on the energy status of isolated rat liver cells in vitro."	3.67	Energy deficits in hepatocytes isolated from phenobarbital-treated or fasted rats and briefly exposed to halothane and hypoxia in vitro. ( Albrecht, RF; Becker, GL; Hensel, P; Holland, AD; Miletich, DJ, 1986)
"The effect of halothane on the pressor responses to hypoxia (3% O2, 5% CO2, balance N2) and to Angiotensin II (Ang II) (0."	3.67	The actions of halothane, ibuprofen and BW755C on hypoxic pulmonary vasoconstriction. ( Kim, SD; Marshall, BE; Marshall, C, 1987)
"Oxygen consumption, cardiac output, and tissue oxygen delivery were measured in normoxic and hypoxic 1-3-day-old lambs during the following six conditions: 1) (control) paralysis with pancuronium and controlled ventilation with room air; 2) paralysis, controlled ventilation and hypoxia (PaO2 = 30 +/- 3 mmHg, [SD]); 3) paralysis, controlled ventilation with room air and 0."	3.67	The cardiovascular and metabolic effects of halothane in normoxic and hypoxic newborn lambs. ( Cameron, CB; Gregory, GA; Heymann, M; Rudolph, AM, 1985)
"A rat model of enflurane-associated hepatotoxicity was compared with the halothane-hypoxia (HH) model (adult male rats, phenobarbital induction, 1% halothane, 14% O2, for 2 hr)."	3.67	Comparison of the requirements for hepatic injury with halothane and enflurane in rats. ( Brown, BR; Gandolfi, AJ; Lind, RC; Sipes, IG, 1985)
"The pulmonary vascular response to alveolar hypoxia with and without halothane exposure was measured in dogs."	3.66	Effect of halothane on the pulmonary vascular response to hypoxia in dogs. ( Fargas-Babjak, A; Forrest, JB, 1979)
"To evaluate the relative importance of halothane metabolism and liver hypoxia in the occurrence of hepatic injury, the injury produced in hypoxic rats exposed to identical MAC hours of halothane but at various concentrations of halothane was compared."	3.66	Hypoxia may be more important than reductive metabolism in halothane-induced hepatic injury. ( Eger, EI; Johnson, BH; Shingu, K, 1982)
" Studies were performed to determine whether hypoxia, respiratory acidosis or deep halothane anaesthesia modify the cardiovascular effect of vagal stimulation (VS) in dogs."	3.66	Effect of supramaximal vagal stimulation in combination with hypoxia, respiratory acidosis and deep halothane anaesthesia on cardiovascular function in dogs. ( Bastron, RD; Korttila, K, 1982)
"Halothane is known to inhibit the ventilatory responses to hypoxia and hypercapnia."	3.66	Halothane depresses the response of carotid body chemoreceptors to hypoxia and hypercapnia in the cat. ( Davies, RO; Edwards, MW; Lahiri, S, 1982)
"Factors affecting halothane (H) hepatotoxicity were investigated in two animal models: 1) the phenobarbital-hypoxia model, and 2) the triiodothyronine (T3) model; in the latter we previously have shown that centrilobular necrosis occurs in T3 pretreated rats anesthetized with 1% H, in 21% oxygen for 2 h."	3.66	Contrasting effects on halothane hepatotoxicity in the phenobarbital-hypoxia and triiodothyronine model: mechanistic implications. ( Phythyon, JM; Uetrecht, J; Wood, AJ; Wood, M, 1983)
"Halothane hepatotoxicity was observed after exposing hyperthyroid rats to 0."	3.66	Halothane hepatotoxicity in hyperthyroid rats as compared to the phenobarbital-hypoxia model. ( Frühling, A; Siegers, CP; Younes, M, 1983)
"To evaluate the importance of hypoxia itself on halothane-induced hepatic injury in the rat, the question of whether hypoxia could injure the liver without causing death was investigated."	3.66	Hypoxia per se can produce hepatic damage without death in rats. ( Eger, EI; Johnson, BH; Shingu, K, 1982)
"Recent investigations have revealed that a number of inhalation anesthetics, including halothane, inhibit the pulmonary vasoconstrictor response to hypoxia without affecting other vasoconstrictor stimuli."	3.66	The pulmonary vasoconstrictor response to hypoxia. The hypoxia-sensitive site studied with a volatile inhibitor. ( Bjertnaes, LJ; Hauge, A; Torgrimsen, T, 1980)
"Exposure of phenobarbital-pretreated male Sprague-Dawley rats to halothane, 1 per cent, for two hours under conditions of hypoxia (FIO2 0."	3.66	An animal model of halothane hepatotoxicity: roles of enzyme induction and hypoxia. ( Brown, BR; McLain, GE; Sipes, IG, 1979)
" Halothane hepatotoxic was produced in all rat strains by exposing phenobarbital-pretreated rats to 1 per cent halothane under mild hypoxia (14 per cent oxygen, inspired) for 2 h."	3.66	Genetic differences in reductive metabolism and hepatotoxicity of halothane in three rat strains. ( Adams, JF; Cousins, MJ; Gourlay, GK; Hall, P, 1981)
"To elucidate the effects of halothane on chemical regulation of ventilation in man, the authors studied the ventilatory responses to isocapnic hypoxia and hyperoxic hypercapnia in 33 human subjects while fully conscious and during sedation or anesthesia with halothane, ."	3.66	Ventilatory responses to hypoxia and hypercapnia during halothane sedation and anesthesia in man. ( Gelb, AW; Knill, RL, 1978)
"The action of halothane on the pulmonary vasoconstrictor response to unilateral alveolar hypoxia was studied in two groups of dogs."	3.66	Preservation of the pulmonary vasoconstrictor response to alveolar hypoxia during the administration of halothane to dogs. ( Arnot, RN; Gibbs, JM; Loh, L; Marin, JB; Obdrzalek, J; Sykes, MK, 1978)
"The effects of halothane and diethyl ether on pulmonary vascular resistance and the pulmonary vasoconstrictor response to alveolar hypoxia were studied in the innervated perfused cat lung."	3.65	The effects of halothane and ether on the pulmonary circulation in the innervated perfused cat lung. ( Chakrabarti, MK; Loh, L; Sykes, MK, 1977)
"The ventilatory responses to isocapnic hypoxia and hypercapnia were studied in six dogs each with a tracheostomy, awake and during anaesthesia with halothane, enflurane and isoflurane (1-2."	3.65	Depression of hypoxic ventilatory response by halothane, enflurane and isoflurane in dogs. ( Cohen, PJ; Hirshman, CA; McCullough, RE; Weil, JV, 1977)
"After long-term exhibition to halothane (up to 96 hours), centrolobular hepatic damage (fatty degeneration, necrobiosis and necrosis) developed in rats, proportionally to the number of anesthesias and shortening of the intervals."	3.65	[Liver-damaging action of halothane--an animal experiment study]. ( Barz, H; Wolf, R, 1975)
" In the tetraplegics undergoing urological surgery, severe hypertension resulting from visceral stimulation was effectively reduced by halothane."	3.65	Circulatory reflexes in tetraplegics during artifical ventilation and general anaesthesia. ( Frankel, HL; Mathias, CJ; Welply, NC, 1975)
"Awareness of the problems of hypoxemia during general anesthesia and an appropriate response by the anesthesiologist, however, is a prerequisite of good medical practice."	2.36	Hypoxemia and general anesthesia: an analysis of distribution of ventilation and perfusion. ( Bagshaw, RJ; Klineberg, PL, 1981)
"Propofol treatment, by inhibiting the NF-kappaB signal transduction pathway, might block the production of noxious mediators involved in the development of halothane-induced injury."	1.33	Halothane induces oxidative stress and NF-kappaB activation in rat liver: protective effect of propofol. ( Amaral, JL; Brasil, LJ; González-Gallego, J; Kretzmann, NA; Marroni, N; San-Miguel, B; Tuñón, MJ; Zettler, CG, 2006)
"Argon-induced anoxia appears to be the first choice from a welfare point of view for killing pigs, based on its lack of aversive properties and its effectiveness in rapidly abolishing brain responsiveness."	1.30	Welfare implications of gas stunning pigs: 3. The time to loss of somatosensory evoked potentials and spontaneous electrocorticogram of pigs during exposure to gases. ( Johnson, SP; McInstry, JL; Raj, AB; Wotton, SB, 1997)
"When halothane was added on reoxygenation, Ca2+ oscillations were markedly reduced (4+/-2 per minute, P<."	1.30	Halothane protects cardiomyocytes against reoxygenation-induced hypercontracture. ( Balser, C; Ladilov, YV; Piper, HM; Schlack, W; Siegmund, B, 1997)
"Halothane anesthesia and hypoxemia were associated with hepatic insult."	1.29	Effects of inhalation anesthetic agents on response of horses to three hours of hypoxemia. ( Steffey, EP; Whitehair, KJ; Willits, NH; Woliner, MJ, 1996)
"Glutamate released during hypoxia or anoxia was 1."	1.29	Volatile and intravenous anesthetics decrease glutamate release from cortical brain slices during anoxia. ( Bickler, PE; Buck, LT; Feiner, JR, 1995)
"During anoxia (O2 replaced by N2), increases in lactate were also seen with glucose; and ATP/ADP decreased to similarly low values with both substrates."	1.28	Isoflurane partially preserves energy balance in isolated hepatocytes during in vitro anoxia. ( Becker, GL; Hanson, KA; Landers, DF; Pathak, BL; Reilly, PJ, 1991)
"Cromolyn sodium has been reported to inhibit hypoxic pulmonary vasoconstriction (HPV) in dogs and sheep, presumably by stabilizing mast cell membranes and thereby preventing the release of mediators such as leukotrienes."	1.28	Cromolyn sodium does not inhibit hypoxic pulmonary vasoconstriction in sheep. ( Pearl, RG, 1990)
" In Study II a dose-response curve was established for the potent stimulator (Sin 1) of the enzyme guanylate cyclase."	1.28	Endothelium-derived relaxing factor is not responsible for inhibition of hypoxic pulmonary vasoconstriction by inhalational anesthetics. ( Marshall, BE; Marshall, C, 1990)
"Upon exposure to halothane, hypoxemia-driven ventilation decreased promptly and progressively (from 7."	1.27	Site of selective action of halothane on the peripheral chemoreflex pathway in humans. ( Clement, JL; Knill, RL, 1984)
"The physical stability and low blood solubility of the new inhaled anesthetic, I-653, imply that this agent produces limited or no toxic effects."	1.27	Studies of the toxicity of I-653, halothane, and isoflurane in enzyme-induced, hypoxic rats. ( Eger, EI; Ferrell, LD; Johnson, BH; Strum, DP, 1987)
"Enflurane was the most potent myocardial depressor and isoflurane the most potent vasodilator, halothane being intermediate."	1.27	Cardiovascular and blood gas responses to inhaled anaesthetics in normoxic and hypoxic dogs. ( Deloof, T; Lambert, M; Leeman, M; Lejeune, P; Naeije, R, 1986)
"The phenomenon of "diffusion hypoxemia" seems to be a well-defined entity."	1.26	The significance of diffusion hypoxemia. ( Corssen, G; Erdmann, W; Holcomb, C, 1976)
"In the awake state, arterial hypoxemia is counteracted by a mechanism which tends to normalize the ventilation/perfusion ratio of the lungs by way of a hypoxia-induced vasoconstriction in poorly ventilated areas."	1.26	Hypoxia-induced vasoconstriction in isolated perfused lungs exposed to injectable or inhalation anesthetics. ( Bjertnaes, LJ, 1977)
"When halothane was administered with adequate oxygen the percentage of the cardiac output delivered to the hepatic artery significantly increased but there was no change in absolute blood flow to either the hepatic artery or portal vein."	1.26	Hepatic blood flow in phenobarbital-pretreated rats during halothane anesthesia and hypoxia. ( Daggy, BP; Ross, WT, 1981)

Timeframe	Studies, this research(%)	All Research%
pre-1990	186 (72.37)	18.7374
1990's	51 (19.84)	18.2507
2000's	16 (6.23)	29.6817
2010's	4 (1.56)	24.3611
2020's	0 (0.00)	2.80

Trial			Phase	Enrollment	Study Type	Start Date	Status
Influence of Different Anesthetic Procedures on Sleep Disorder Breathing in Adult Patients Undergoing Elective Surgery[NCT03499132]				90 participants (Actual)	Observational	2018-03-01	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Halothane hepatitis and the anaesthesiologist. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Jan-21, Volume: 65, Issue:3 Topics: Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Halothane; Hu	1984
Hypoxemia and general anesthesia: an analysis of distribution of ventilation and perfusion. International anesthesiology clinics, 1981,Fall, Volume: 19, Issue:3 Topics: Anesthesia, General; Anesthesia, Inhalation; Halothane; Humans; Hypotension, Controlled; Hypoxia; In	1981
Congenital anomalies and inhalation anesthetics. Journal of the American Dental Association (1939), 1976, Volume: 93, Issue:3 Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Anesthesia, Inhalation; Anesthetics; Animals; Co	1976
Perspectives in the pathogenesis of halothane-induced hepatitis. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1986, Jun-21, Volume: 69, Issue:13 Topics: Animals; Chemical and Drug Induced Liver Injury; Halothane; Humans; Hypoxia; Rats	1986
Malignant hyperthermia: a statistical review. Canadian Anaesthetists' Society journal, 1970, Volume: 17, Issue:4 Topics: Acidosis; Acidosis, Respiratory; Adolescent; Adult; Anesthesia, General; Anesthesia, Inhalation; Bio	1970
Postoperative jaundice. The New England journal of medicine, 1973, Feb-08, Volume: 288, Issue:6 Topics: Bacterial Infections; Bile Pigments; Bilirubin; Chemical and Drug Induced Liver Injury; Cholecystiti	1973
[Basis and new aspects of the effect of anaesthetics on cerebral function]. Der Anaesthesist, 1973, Volume: 22, Issue:4 Topics: Anesthetics; Barbiturates; Brain; Brain Edema; Brain Neoplasms; Cerebrovascular Circulation; Chlorof	1973
Postoperative juandice. The Surgical clinics of North America, 1974, Volume: 54, Issue:3 Topics: Aminosalicylic Acids; Anemia, Hemolytic; Bile Ducts; Bilirubin; Chemical and Drug Induced Liver Inju	1974
Effects of halothane on hepatic function. Clinical anesthesia, 1968, Volume: 1 Topics: Age Factors; Alkaline Phosphatase; Anesthesia, General; Anesthesia, Inhalation; Animal Nutritional P	1968
Advances in anaesthesia. The Practitioner, 1968, Volume: 201, Issue:204 Topics: Analgesics; Anesthesia; Anesthesia, General; Anesthesia, Intravenous; Body Fluids; Halothane; Humans	1968
[Basic and clinical studies on physiological lung shunt in anesthesia. 2]. Masui. The Japanese journal of anesthesiology, 1969, Volume: 18, Issue:7 Topics: Age Factors; Anesthesia, General; Animals; Carbon Dioxide; Dogs; Ethyl Ethers; Halothane; Heart Rate	1969
Splanchnic blood flow during anesthesia. International anesthesiology clinics, 1969,Summer, Volume: 7, Issue:2 Topics: Abdomen; Anesthesia, Conduction; Anesthetics; Animals; Blood Flow Velocity; Blood Glucose; Carbon Di	1969
Cardiac arrhythmias during anesthesia and operation. Anesthesiology, 1970, Volume: 33, Issue:2 Topics: Acidosis, Respiratory; Age Factors; Anesthesia; Anesthetics; Animals; Arrhythmia, Sinus; Arrhythmias	1970

Article	Year
Antioxidants prevent depression of the acute hypoxic ventilatory response by subanaesthetic halothane in men. The Journal of physiology, 2002, 11-01, Volume: 544, Issue:3 Topics: Acute Disease; Adult; alpha-Tocopherol; Anesthetics, Inhalation; Antioxidants; Ascorbic Acid; Haloth	2002
Influence of halothane-diethyl-ether azeotrope and isoflurane on ventilation. Re-evaluation of an obsolete drug. Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:1 Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Bone and Bones; Carbon Dioxid	1995
Influence of a subanesthetic concentration of halothane on the ventilatory response to step changes into and out of sustained isocapnic hypoxia in healthy volunteers. Anesthesiology, 1994, Volume: 81, Issue:4 Topics: Adult; Anesthesia, Inhalation; Blood Gas Analysis; Carbon Dioxide; Chemoreceptor Cells; Dose-Respons	1994
Laryngeal mask airway vs face mask and Guedel airway during pediatric myringotomy. Archives of otolaryngology--head & neck surgery, 1994, Volume: 120, Issue:8 Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Child; Consciousness; Female; Halothane; Humans;	1994
Comparison of the effects of sub-hypnotic concentrations of propofol and halothane on the acute ventilatory response to hypoxia. British journal of anaesthesia, 1995, Volume: 75, Issue:6 Topics: Adolescent; Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Carbon Dioxide; Dose-Response	1995
Comparative study between the effects of total intravenous anesthesia with propofol and balanced anesthesia with halothane on the alveolar-arterial oxygen tension difference and on the pulmonary shunt. Archives of medical research, 1992,Autumn, Volume: 23, Issue:3 Topics: Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Female; Halothane; Humans; Hypoxia; Male; Mi	1992
Emergence respiratory complications in children: a comparison between halothane and isoflurane. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:4 Pt 2 Topics: Anesthesia, Closed-Circuit; Anesthesia, Inhalation; Child; Child, Preschool; Double-Blind Method; Em	1990
The clinical significance of diffusion hypoxia in children. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:4 Pt 2 Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Inhalation; Child; Child, Preschool; Di	1990
Oxygen saturation during inhalation induction with halothane and isoflurane in children: effect of premedication with rectal thiopentone. British journal of anaesthesia, 1990, Volume: 64, Issue:2 Topics: Administration, Rectal; Anesthesia, Inhalation; Child; Child, Preschool; Female; Halothane; Humans;	1990
Chloroform anaesthesia. A clinical comparison of chloroform and halothane administered from precision vaporisers. Anaesthesia, 1968, Volume: 23, Issue:4 Topics: Anesthesia, Inhalation; Atropine; Bradycardia; Cardiac Complexes, Premature; Chloroform; Female; Hal	1968
Observations of blood lactate and pyruvate levels and excess lactate production during and after anaesthesia with and without hyperventilation. British journal of anaesthesia, 1968, Volume: 40, Issue:5 Topics: Acid-Base Equilibrium; Adult; Anesthesia, Inhalation; Blood Gas Analysis; Citric Acid Cycle; Female;	1968

halothane and Anoxemia

Research Excerpts

Research

Studies (257)

Authors

Clinical Trials (1)

Trial Overview

Reviews

Trials

Other Studies

Authors	Studies
Karanovic, N	1
Pecotic, R	1
Valic, M	1
Jeroncic, A	1
Carev, M	1
Karanovic, S	1
Ujevic, A	1
Dogas, Z	2
Kobayashi, N	1
Yamamoto, Y	1
Pandit, JJ	4
Buckler, KJ	2
Winter, V	1
Bayliss, R	1
Teppema, LJ	1
Nieuwenhuijs, D	1
Sarton, E	1
Romberg, R	1
Olievier, CN	1
Ward, DS	1
Dahan, A	4
HALEY, FC	2
WYANT, GM	1
BACSA, S	1
CZAKO, Z	1
ARANYOSI, J	1
TAYLOR, SH	1
SCOTT, DB	1
DONALD, KW	1
GORDH, T	1
MARKELLO, R	1
KING, BD	1
BUCKLEY, MJ	1
MCLAUGHLIN, JS	1
FORT, L	1
SAIGUSA, M	1
MORROW, DH	1
PHILIPPART, C	1
CLARK, MM	1
GARDINER, AJ	1
PALMER, KN	1
SMITH, WD	1
JONES, HD	1
MCLAREN, CA	1
WILHJELM, BJ	3
ARNFRED, I	1
SCHWEIKERT, CH	1
KAPFHAMMER, V	1
Takahashi, T	2
Osanai, S	2
Nakano, H	2
Ohsaki, Y	2
Kikuchi, K	2
Campanucci, VA	1
Fearon, IM	1
Nurse, CA	1
Caley, AJ	1
Gruss, M	1
Franks, NP	1
Moreau, B	2
Donoghue, S	1
Robbins, PA	3
Yu, WF	1
Yang, LQ	1
Zhou, MT	1
Liu, ZQ	1
Li, Q	1
Brasil, LJ	1
San-Miguel, B	1
Kretzmann, NA	1
Amaral, JL	1
Zettler, CG	1
Marroni, N	1
González-Gallego, J	1
Tuñón, MJ	1
Crawford, MW	1
Shichor, T	1
Engelhardt, T	1
Adamson, G	1
Bell, D	1
Carmichael, FJ	1
Kim, PC	1
Zolnikov, SM	1
Koljutskaja, OD	1
Alexandrov, VM	1
Dobkin, AB	2
Byles, PH	2
Africa, BF	1
Neville, JF	2
Saidman, LJ	1
Eger, EI	9
Nishino, T	3
Yonezawa, T	2
Honda, Y	2
Shipton, EA	1
Kruger, AE	1
Knill, RL	7
Clement, JL	3
Jurdi-Nuwayhid, F	1
Chmielnicki, Z	1
Fassoulaki, A	1
Johnson, BH	4
Ferrell, LD	2
Smuckler, EA	1
Harper, MH	1
Eger, RR	1
Cahalan, MK	1
Horikawa, H	1
Higuchi, T	1
Sakai, M	1
Ohta, F	1
Kato, Y	1
Ichiyanagi, K	1
Izumi, S	1
Shingu, K	2
Siegers, CP	1
Frühling, A	1
Younes, M	1
Uetrecht, J	1
Wood, AJ	1
Phythyon, JM	1
Wood, M	1
Bjertnaes, LJ	6
Klineberg, PL	1
Bagshaw, RJ	1
Davies, RO	1
Edwards, MW	1
Lahiri, S	1
Korttila, K	1
Bastron, RD	1
Vanevski, VL	1
Mikhaĭlovich, VL	1
Ross, WT	2
Daggy, BP	2
Gelman, S	3
Gourlay, GK	4
Adams, JF	2
Cousins, MJ	6
Hall, P	2
Data, PG	1
Di Tano, G	1
Cacchio, M	1
Della Valle, R	1
Forsling, ML	1
Ingram, DL	1
Stanier, MW	1
Hauge, A	2
Torgrimsen, T	1
Praud, JP	1
Diaz, V	1
Kianicka, I	1
Dalle, D	1
van den Elsen, M	1
DeGoede, J	3
Berkenbosch, A	3
van Kleef, J	1
Kalman, SH	1
Johnson, A	1
Gaudy, JH	3
Quignon, M	2
Sicard, JF	3
Maneglia, R	2
Palmisano, BW	1
Mehner, RW	1
Baker, JE	1
Stowe, DF	3
Bosnjak, ZJ	6
Kampine, JP	7
Stadnicka, A	1
Stekiel, TA	2
Hogan, QH	1
van den Elsen, MJ	2
Olievier, IC	2
Burm, AG	1
van Kleef, JW	2
Atos, MQ	1
Bovill, JG	1
Watcha, MF	1
Garner, FT	1
White, PF	1
Lusk, R	1
Young, CH	1
Drummond, GB	1
Warren, PM	1
Kamath, GS	1
Rorie, DK	1
Tyce, GM	1
Bickler, PE	1
Buck, LT	1
Feiner, JR	1
Johnson, ME	1
Sill, JC	1
Uhl, CB	1
Halsey, TJ	1
Gores, GJ	1
Whitehair, KJ	1
Steffey, EP	1
Woliner, MJ	1
Willits, NH	1
Nagyova, B	1
Dorrington, KL	1
Gill, EW	1
Morray, JP	1
Nobel, R	1
Bennet, L	1
Hanson, MA	1
Forster, HV	1
Gozal, D	1
Harper, RM	1
Lowry, TF	1
Ohtake, PJ	1
Pan, LG	1
Rector, DM	1
McKinley, BA	1
Morris, WP	1
Parmley, CL	1
Butler, BD	2
Raj, AB	1
Johnson, SP	1
Wotton, SB	1
McInstry, JL	1
Stuth, EA	1
Krolo, M	1
Hopp, FA	1
Zuperku, EJ	1
Siegmund, B	1
Schlack, W	1
Ladilov, YV	1
Balser, C	1
Piper, HM	1
El-Bassiouni, EA	1
Abo-Ollo, MM	1
Helmy, MH	1
Ismail, S	1
Ramadan, MI	1
Taylor, PM	1
Ide, T	1
Sakurai, Y	1
Aono, M	1
Yondov, D	1
Kounev, V	1
Ivanov, O	1
Prisadov, G	1
Semerdjieva, M	1
Haddad, E	1
Lebuffe, G	1
Boillot, A	1
Imbenotte, M	1
Vallet, B	1
Maruyama, R	1
Fukuda, Y	1
Stegmann, GF	1
Kil, HK	1
De Crescenzo, V	1
Dubuis, E	1
Constantin, S	1
Rebocho, M	1
Girardin, C	1
Bonnet, P	1
Vandier, C	1
Raff, H	1
Kafer, ER	2
Marsh, HM	1
Nahrwold, ML	1
Lust, WD	1
Passonneau, JV	1
Bennetts, FE	1
Nathan, MA	1
Reis, DJ	1
Sharp, JH	1
Haynes, WD	1
Whitehead, R	1
Gorsky, BH	1
Cascorbi, HF	1
Vance, JP	1
Brown, DM	1
Smith, G	1
Thorburn, J	1
McLain, GE	1
Sipes, IG	2
Brown, BR	2
Cardell, RR	1
Manninen, P	1
Ota, N	1
Kam, CA	1
Hägerdal, M	1
Welsh, FA	1
Keykhah, MM	2
Perez, E	1
Harp, JR	2
Andreen, M	1
Irestedt, L	1
Gelb, AW	3
Sykes, MK	7
Gibbs, JM	3
Loh, L	5
Marin, JB	1
Obdrzalek, J	1
Arnot, RN	1
Fargas-Babjak, A	1
Forrest, JB	1
Strohmeyer, G	1
Berges, W	1
Bussard, DA	1
Holcomb, C	1
Erdmann, W	1
Corssen, G	1
Chakrabarti, MK	4
Hirshman, CA	1
McCullough, RE	1
Cohen, PJ	2
Weil, JV	1
Katzin, DB	1
Rubinstein, EH	1
Wolf, R	1
Barz, H	1
Welply, NC	1
Mathias, CJ	1
Frankel, HL	1
Kramer, M	1
L'Allemand, H	2
Nakken, KF	1
Bredesen, JE	1
Krechkovskiĭ, EA	1
Kiseleva, AF	1
Kolesova, NA	1
Anisimova, IG	1
Widger, LA	1
Gandolfi, AJ	2
Van Dyke, RA	1
Roberts, JG	2
Foëx, P	3
Clarke, TN	2
Prys-Roberts, C	2
Bennett, MJ	2
Shelley, FC	1
Giler, S	1
Ventura, E	1
Levy, E	1
Urca, I	1
Sperling, O	1
de Vries, A	1
Mendoza, CU	1
Suárez, M	1
Castañeda, R	1
Hernández, A	1
Sánchez, R	1
Tominaga, M	1
Johnson, DH	2
Chang, PC	1
Hurst, TS	2
Reynolds, FB	1
Lang, SA	1
Mayers, I	4
Ishibe, Y	2
Umeda, T	2
Shiokawa, Y	1
Izumi, T	2
Nakamura, M	2
Uno, H	1
Suekane, K	2
Heavner, JE	1
Dryden, CF	1
Sanghani, V	1
Huemer, G	1
Bessire, A	1
Badgwell, JM	1
Pearl, RG	2
Prielipp, RC	1
Monroe, SM	1
Marijic, J	2
Theissen, JL	1
Traber, LD	1
Herndon, DN	1
Traber, DL	1
Strebel, S	1
Frei, F	1
Skarvan, K	1
Murakami, Y	1
Lehot, JJ	1
Leone, BJ	1
Arimura, H	1
Hoka, S	1
Pathak, BL	1
Becker, GL	2
Reilly, PJ	1
Hanson, KA	1
Landers, DF	1
Johnson, D	3
Hurst, T	2
Pounder, DR	1
Blackstock, D	1
Steward, D	1
Murphy, IL	1
Splinter, WM	1
Turner, LA	1
To, T	1
Raftery, S	1
Warde, D	1
Mayers, T	1
Marshall, C	2
Marshall, BE	2
LaManna, JC	1
McCracken, KA	1
Patil, M	1
Prohaska, OJ	1
Matsumoto, N	1
Ohara, K	1
Yoshida, N	1
Nakamura, S	1
Nagasaka, H	1
Aikawa, K	1
Miyazaki, T	1
Hori, T	1
Kjaeve, J	1
Smith, DS	1
O'Neill, JJ	1
Thomson, KD	1
Inoue, T	1
Payne, JP	2
de Groot, H	1
Noll, T	1
Kim, SD	1
Knights, KM	2
Fischler, M	1
Seigneur, F	1
Bellier, M	1
Lechien, J	1
Vourc'h, G	1
Yaster, M	1
Schieble, TM	1
Costa, AK	1
Heffel, DF	1
Trudell, JR	1
Abballe, C	1
Sabato, AF	1
Stefanelli, A	1
Calimici, R	1
Morelli Sbarra, G	1
Owen, AD	1
van der Veen, BW	1
Plummer, JL	3
Jenner, M	1
Doss, NW	1
Wainfeld, M	1
Thakur, JG	1
Pierre, AM	1
Spatz, RJ	1
Abadir, AR	1
Gintautas, J	1
Hall, PD	1
Jenner, MA	2
Strum, DP	1
Leiman, BC	1
Katz, J	1
Baba, H	1
Hensel, P	1
Holland, AD	1
Miletich, DJ	1
Albrecht, RF	1
Naeije, R	1
Lambert, M	1
Lejeune, P	1
Leeman, M	1
Deloof, T	1
Kohchi, T	1
Mizuguchi, T	1
Hall, PM	1
Cameron, CB	1
Gregory, GA	2
Rudolph, AM	1
Heymann, M	1
Lind, RC	1
González-Méndez, R	1
McNeill, A	1
Wall, SD	1
Gooding, CA	1
Litt, L	1
James, TL	1
St John, WM	1
Bledsoe, TA	1
Lloyd, EL	1
Biebuyck, JF	1
Oduntan, SA	1
Jackson, DC	1
Britt, BA	2
Kalow, W	1
Hartmann, H	1
Buchholz, W	1
Mügge, L	1
Galindo, A	1
Wilhjelm, B	1
Mueller, RA	1
Lee, DC	1
Lee, MO	1
Clifford, DH	1
Tait, AR	1
Weiskopf, RB	1
Raymond, LW	1
Severinghaus, JW	2
Leinweber, B	1
Cüppers, M	1
Bech-Jansen, P	2
Johansen, SH	1
Jordanov, J	1
Ruben, H	1
Gerring, EL	1
Scarth, SC	1
Chadwick, DA	1
LaMont, JT	2
Isselbacher, KJ	1
Pichlmayr, I	1
Millar, RA	1
Kurimoto, S	1
Higo, GI	1
Huse, K	1
Nicola, E	1
Jeuken, B	1
Okamoto, T	1
Davies, DM	2
Green, JD	1
Robinson, AE	1
Sheikolislam, J	1
Kubota, T	1
Counts, HK	1
Carden, WD	1
Petty, WC	1
Cullen, DJ	5
Rasmussen, JP	1
Michenfelder, JD	1
Shigematsu, A	1
Takahashi, S	1
Furukawa, T	1
Little, DM	1
Harrison, GA	2
Bailey, RJ	1
Thomson, PG	1
Kaito, K	1
Savolainen, VP	1
Katz, RL	1
Bigger, JT	1
Sutton, J	1
Hickie, JB	1
Kitamura, H	1
Sawa, T	1
Ikezono, E	1
Hauenschild, E	1
Nisbet, HI	1
Gray, IG	1
Olley, PM	1
Johnston, AE	1
Seed, RF	1
Hauck, W	1
Verzella, F	1
Theye, RA	1
Kaplan, JA	1
Bitner, RL	1
Dripps, RD	1
Reske-Nielsen, E	1
Kratholm, S	1
Coultas, RJ	1
Strunin, L	1
Walker, WD	1
Strunin, JM	1
Reynard, A	1
Simpson, BR	1
Cotev, S	1
Hornbein, TF	1
Natsui, T	1
Yanagida, H	1
Suwa, K	1
Parbrook, GD	1
McDowall, DG	1
Gutiérrez Goicoechea, JM	1
Heidel, HJ	1
Skrzypczak, J	1
Freiberger, KU	1
Havers, L	1
Koenen, FW	1
Siedek, M	1
Wollman, H	1
Alexander, SC	1
König, G	1
Pliess, G	1
Schilling, K	1
Martinez, LR	1
Norlander, OP	1
Rawstron, RE	2
Chamberlain, JH	1
Lis, MT	1
Brendel, B	1
Nikki, P	1
Tammisto, T	1
Vit, R	1
Gordon, RA	1
Schweizer, O	1
Howland, WS	1
Kübler, W	1
Punnoose, VA	1
Tandan, GC	1
Hatangdi, VS	1
Iyengar, NR	1
Allison, SP	1
Tomlin, PJ	1
Chamberlain, MJ	1
Efuni, SN	1
Trusov, VS	1
Rabinovich, NE	1