halothane has been researched along with Anesthesia Related Hyperthermia in 702 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The most commonly used laboratory test for predicting malignant hyperthermia susceptibility is the caffeine halothane contracture test." | 9.07 | Prediction of malignant hyperthermia susceptibility in low-risk subjects. An epidemiologic investigation of caffeine halothane contracture responses. The North American Malignant Hyperthermia Registry. ( Bunn, JS; Diaz, M; Landis, JR; Larach, MG, 1992) |
| " The center followed the diagnostic protocols of the North America MH Group, in which the contractures of biopsies from the vastus lateralis muscle are analyzed after exposure to caffeine and halothane (CHCT)." | 7.76 | Use of the caffeine-halothane contracture test for the diagnosis of malignant hyperthermia in Brazil. ( Abreu, AV; Aguiar, MI; Cardoso, LA; Carmo, PL; Cunha, LB; Matos, AR; Sudo, RT; Trachez, MM; Zapata-Sudo, G, 2010) |
| "The caffeine-halothane contracture test (CHCT) is the only recognized laboratory test to diagnose malignant hyperthermia (MH)." | 7.70 | The sensitivity and specificity of the caffeine-halothane contracture test: a report from the North American Malignant Hyperthermia Registry. The North American Malignant Hyperthermia Registry of MHAUS. ( Allen, GC; Kunselman, AR; Larach, MG, 1998) |
| "Contracture responses of intact cut masseter and vastus bundles (non-skinned) do not differ with respect to caffeine and halothane." | 7.70 | Caffeine- or halothane-induced contractures of masseter muscle are similar to those of vastus muscle in normal humans. ( Antognini, JF; Gronert, GA; Melton, AT, 1999) |
| " We evaluated whether toxic concentrations of cocaine altered the in vitro muscle response to halothane during contracture tests for MH." | 7.69 | Effect of cocaine on the contracture response to 1% halothane in patients undergoing diagnostic muscle biopsy for malignant hyperthermia. ( Brum, JM; DeBoer, GE; Mitsumoto, H; Sato, N, 1995) |
| " This has precluded the use of halothane anesthesia." | 7.67 | [Halothane anesthesia of several hours' duration in swine of the German Landrace breed, selected for resistance to malignant hyperthermia]. ( Ellendorff, F; Nowak, R, 1989) |
| "The in vitro halothane and caffeine contracture tests have been performed on muscle tissue from six survivors of the neuroleptic malignant syndrome." | 7.67 | Neuroleptic malignant syndrome and malignant hyperthermia. In vitro comparison with halothane and caffeine contracture tests. ( Adnet, P; Guevart, E; Krivosic-Horber, R; Lestavel, P; Theunynck, D, 1987) |
| " The literature is briefly reviewed and an account of the present status of malignant hyperthermia (porcine stress syndrome) in Ontario boars using the halothane or halothane/succinylcholine screening tests is presented." | 7.66 | Halothane and halothane/succinylcholine induced malignant hyperthermia (porcine stress syndrome) in a population of Ontario boars. ( Basrur, PK; McDonell, WN; Seeler, DC, 1983) |
| "We evaluated six boys who had developed isolated masseter muscle spasm following intravenous succinylcholine." | 7.66 | Masseter spasm induced by succinylcholine in children: contracture testing for malignant hyperthermia: report of six cases. ( Flewellen, EH; Nelson, TE, 1982) |
| "Masseter muscle rigidity was defined clinically by the transient inability to distract the mandible from the maxilla such that the mouth could not be opened or could only be opened with force." | 5.29 | The incidence of masseter muscle rigidity after succinylcholine in infants and children. ( Burrows, FA; Carr, AS; Creighton, RE; Lazzell, VA; Lerman, J, 1994) |
| "The halothane test was performed under different conditions in 10 halothane-sensitive growing pigs (Landrace, line 01)." | 5.29 | [The effect of anesthesia, of an alpha or beta adrenergic blockade in conscious and of adrenaline in anesthetized halothane-positive swine on hematologic and metabolic parameters in the blood during the course of halothane exposure]. ( Gürtler, H; Neubert, E, 1994) |
| "This report describes a cardiac arrest that occurred in a 4-month-old infant during induction of anesthesia." | 5.28 | [Cardiac arrest during anesthesia induction with halothane and succinylcholine in an infant. Massive hyperkalemia and rhabdomyolysis in suspected myopathy and/or malignant hyperthermia]. ( Bachour, H; Mehler, J; Simons, F; Wolpers, K, 1991) |
| "The association of malignant hyperthermia (MH) with neuromuscular disorders has been recognized since 1970." | 5.27 | Halothane-caffeine contracture testing in neuromuscular diseases. ( Fletcher, JE; Heiman-Patterson, TD; Rosenberg, H; Tahmoush, AJ, 1988) |
| "A case of probable crisis of malignant hyperthermia triggered by halothane is reported." | 5.27 | [Carpopedal spasm during anesthesia with halothane: malignant hyperthermia or tetany?]. ( Kancir, CB, 1986) |
| "The most commonly used laboratory test for predicting malignant hyperthermia susceptibility is the caffeine halothane contracture test." | 5.07 | Prediction of malignant hyperthermia susceptibility in low-risk subjects. An epidemiologic investigation of caffeine halothane contracture responses. The North American Malignant Hyperthermia Registry. ( Bunn, JS; Diaz, M; Landis, JR; Larach, MG, 1992) |
| " However, experts worldwide agree that the only reference test to this day remains the in vitro halothane caffeine contracture tests." | 4.77 | [Screening tests for malignant hyperthermia susceptibility]. ( Adnet, P; Krivosic-Horber, R, 1989) |
| " The center followed the diagnostic protocols of the North America MH Group, in which the contractures of biopsies from the vastus lateralis muscle are analyzed after exposure to caffeine and halothane (CHCT)." | 3.76 | Use of the caffeine-halothane contracture test for the diagnosis of malignant hyperthermia in Brazil. ( Abreu, AV; Aguiar, MI; Cardoso, LA; Carmo, PL; Cunha, LB; Matos, AR; Sudo, RT; Trachez, MM; Zapata-Sudo, G, 2010) |
| " Exposure of CASQ1-null mice to either 2% halothane or heat stress triggers lethal episodes characterized by whole-body contractures, elevated core temperature, and severe rhabdomyolysis, which are prevented by prior dantrolene administration." | 3.75 | Anesthetic- and heat-induced sudden death in calsequestrin-1-knockout mice. ( Canato, M; Dainese, M; Dirksen, RT; Lyfenko, AD; Paolini, C; Protasi, F; Quarta, M; Reggiani, C, 2009) |
| "We describe a child who developed a malignant hyperthermia-like syndrome after exposure to succinylcholine and halothane." | 3.75 | Malignant hyperthermia-like syndrome and carnitine palmitoyltransferase II deficiency with heterozygous R503C mutation. ( Hogan, KJ; Vladutiu, GD, 2009) |
| " Genetic screening of a 5-generation Brazilian family with a history of MH-related deaths and a previous MH diagnosis by the caffeine halothane contracture test (CHCT) in some individuals was performed using restriction and sequencing analysis." | 3.75 | Multigenerational Brazilian family with malignant hyperthermia and a novel mutation in the RYR1 gene. ( Amoedo, ND; Cunha, LB; Matos, AR; Rumjanek, FD; Sambuughin, N; Sudo, RT; Zapata-Sudo, G, 2009) |
| "The caffeine-halothane contracture test (CHCT) is the only recognized laboratory test to diagnose malignant hyperthermia (MH)." | 3.70 | The sensitivity and specificity of the caffeine-halothane contracture test: a report from the North American Malignant Hyperthermia Registry. The North American Malignant Hyperthermia Registry of MHAUS. ( Allen, GC; Kunselman, AR; Larach, MG, 1998) |
| " Eight days later, he presented with a neuroleptic malignant syndrome following an injection of droperidol." | 3.70 | Malignant hyperthermia and neuroleptic malignant syndrome in a patient during treatment for acute asthma. ( Cardinaud, JP; Favier, JC; Gbikpi-Benissan, G; Gruson, D; Hilbert, G; Portel, L, 1999) |
| "Contracture responses of intact cut masseter and vastus bundles (non-skinned) do not differ with respect to caffeine and halothane." | 3.70 | Caffeine- or halothane-induced contractures of masseter muscle are similar to those of vastus muscle in normal humans. ( Antognini, JF; Gronert, GA; Melton, AT, 1999) |
| " Diagnosis is based on in vitro muscle contracture in response to halothane and/or caffeine exposure." | 3.70 | [Malignant hyperthermia susceptibility in 3 patients with malignant neuroleptic syndrome]. ( Bahia, VS; Marchiori, PE; Oliveira, RA; Scaff, M; Silva, HC; Tsanaclis, AM, 2000) |
| " We evaluated whether toxic concentrations of cocaine altered the in vitro muscle response to halothane during contracture tests for MH." | 3.69 | Effect of cocaine on the contracture response to 1% halothane in patients undergoing diagnostic muscle biopsy for malignant hyperthermia. ( Brum, JM; DeBoer, GE; Mitsumoto, H; Sato, N, 1995) |
| " The halothane/caffeine contracture test was performed on the biopsied muscle." | 3.69 | Incidence of malignant hyperthermia reactions in 2,214 patients undergoing muscle biopsy. ( Britt, BA; Carr, AS; Cunliffe, M; Lerman, J; McLeod, ME, 1995) |
| "Muscle metabolism was studied in pigs of different halothane genotypes by taking blood and muscle biopsy samples during a 45-min preslaughter period of anesthesia." | 3.69 | Effect of dantrolene treatment on muscle metabolism and meat quality of anesthetized pigs of different halothane genotypes. ( Klont, RE; Lambooy, E; van Logtestijn, JG, 1994) |
| "It has been claimed that the combination of halothane and succinylcholine, commonly used for anesthetic induction during short pediatric otolaryngologic procedures, is associated with a 1% incidence of masseter spasm (MS) which may be an early sign of malignant hyperthermia (MH)." | 3.68 | Masseter spasm and malignant hyperthermia: a retrospective review of a hospital-based pediatric otolaryngology practice. ( Brandom, BW; Chan, KH; Kosko, JR, 1992) |
| " In vitro, human MHS muscle samples were exposed to propofol and changes in (a) baseline tension and (b) contracture tension on exposure to halothane and caffeine were measured." | 3.68 | Propofol is a 'safe' anaesthetic agent in malignant hyperthermia susceptible patients. ( Couchman, KG; McKenzie, AJ; Pollock, N, 1992) |
| "The in vitro contracture test determines the sensitivity of freshly obtained skeletal muscle specimens to caffeine or halothane applied to a bathing solution." | 3.68 | In vitro contracture testing for determination of susceptibility to malignant hyperthermia: a methodologic update. ( Gallagher, WJ; Iaizzo, PA; Wedel, DJ, 1991) |
| "This retrospective study was undertaken to examine the management and outcome of children who developed isolated masseter muscle spasm (MMS) after the administration of intravenous succinylcholine during anesthetic induction." | 3.68 | Masseter muscle spasm in children: implications of continuing the triggering anesthetic. ( Bose, D; Cameron, CB; Littleford, JA; McKillop, C; Patel, LR, 1991) |
| " In the present study the cytoplasmic Ca2+ concentrations of lymphocytes were monitored with indo-1 in 14 control subjects (nine fasted and five nonfasted) and five fasted MH susceptible and three fasted nonsusceptible patients, diagnosed by the halothane and caffeine contracture tests." | 3.68 | Importance of fasting in the lymphocyte calcium test for malignant hyperthermia. ( Allen, GC; Conner, GE; Fletcher, JE; Huggins, FJ; Rosenberg, H, 1990) |
| "In vitro contracture tests for susceptibility to malignant hyperthermia (MH) were performed with halothane and caffeine in 34 patients, according to the protocol of the European MH Group." | 3.68 | Influence of salbutamol on the in vitro muscle response to caffeine and halothane in malignant hyperthermia. ( Bendixen, D; Ording, H, 1990) |
| " In order to provide additional evidence, all eight patients had vastus lateralis muscle biopsies with subsequent caffeine-halothane contracture studies performed." | 3.68 | Malignant hyperthermia in the otolaryngologic patient: prospective anesthetic and surgical management of eight children. ( Dubrow, TJ; Dudley, JP; Reynolds, R, 1990) |
| " The in vitro halothane-caffeine contracture tests are the most reliable method of identifying individuals susceptible to MH." | 3.67 | The association between the neuroleptic malignant syndrome and malignant hyperthermia. ( Adamantidis, MM; Adnet, PJ; Adnet-Bonte, CA; Dupuis, BA; Haudecoeur, G; Krivosic-Horber, RM; Saulnier, F, 1989) |
| " This has precluded the use of halothane anesthesia." | 3.67 | [Halothane anesthesia of several hours' duration in swine of the German Landrace breed, selected for resistance to malignant hyperthermia]. ( Ellendorff, F; Nowak, R, 1989) |
| "The results are reported of the contracture test obtained by using the calcium ionophore A 23187 (Calcimycin) in two patients, the son (A) and the mother (B)." | 3.67 | [Contracture test with ionophore A 23187 for the diagnosis of malignant hyperthermia]. ( Gascard, JP; Kozak-Reiss, G; Laxenaire, MC; Moeller, R, 1986) |
| "The effects of mild Sarcocystis miescheriana infection on blood enzymes and body weight were compared in stress-sensitive (halothane positive) and in stress-insensitive (halothane negative) pigs." | 3.67 | The effects of Sarcocystis miescheriana infections on blood enzymes and weight gain of stress-sensitive and stress-insensitive pigs. ( Bickhardt, K; Daugschies, A; Rommel, M; Schnieder, T, 1988) |
| " Halothane-caffeine contracture tests, interpreted in accordance with the criteria of the European Group on Malignant Hyperthermia, yielded the following results: 13 positive (MHS), 10 negative (MHN), 4 equivocal (MHE)." | 3.67 | [Tests of contracture and sensitivity to malignant hyperthermia in 27 patients]. ( Adamantidis, M; Adnet, P; Guévart, E; Krivosic, I; Krivosic-Horber, R; Theunynck, D, 1988) |
| "The in vitro halothane and caffeine contracture tests have been performed on muscle tissue from six survivors of the neuroleptic malignant syndrome." | 3.67 | Neuroleptic malignant syndrome and malignant hyperthermia. In vitro comparison with halothane and caffeine contracture tests. ( Adnet, P; Guevart, E; Krivosic-Horber, R; Lestavel, P; Theunynck, D, 1987) |
| " She developed the complete symptomatology of malignant hyperthermia triggered by halothane anaesthesia, with tachycardia, cardiac arrhythmia, cyanosis, combined respiratory and metabolic acidosis and hyperpyrexia." | 3.67 | [Malignant hyperthermia in a 41-year-old woman]. ( Popp, M; Seeling, W, 1986) |
| " Following an uneventful induction of anaesthesia with halothane, nitrous oxide and O2, succinylcholine resulted in bilateral masseter muscle spasm and then, in rapid sequence, ventricular tachycardia and cardiac arrest." | 3.67 | Duchenne muscular dystrophy and malignant hyperthermia--two case reports. ( Stanley, TH; Wang, JM, 1986) |
| "Seventy-seven patients who developed masseter muscle rigidity (MMR) after receiving succinylcholine to facilitate tracheal intubation were evaluated for malignant hyperthermia (MH) susceptibility by in vitro halothane and caffeine contracture tests." | 3.67 | Masseter muscle rigidity and malignant hyperthermia susceptibility. ( Fletcher, JE; Rosenberg, H, 1986) |
| " Succinylcholine administration caused prolonged, severe muscle fasciculations followed by tachycardia, and an elevated blood pressure." | 3.67 | Unusual response following use of succinylcholine in a horse anesthetized with halothane. ( Hildebrand, SV; Riedesel, DH, 1985) |
| " The literature is briefly reviewed and an account of the present status of malignant hyperthermia (porcine stress syndrome) in Ontario boars using the halothane or halothane/succinylcholine screening tests is presented." | 3.66 | Halothane and halothane/succinylcholine induced malignant hyperthermia (porcine stress syndrome) in a population of Ontario boars. ( Basrur, PK; McDonell, WN; Seeler, DC, 1983) |
| "We evaluated six boys who had developed isolated masseter muscle spasm following intravenous succinylcholine." | 3.66 | Masseter spasm induced by succinylcholine in children: contracture testing for malignant hyperthermia: report of six cases. ( Flewellen, EH; Nelson, TE, 1982) |
| " A patient with strabismus (esotropia) had tachycardia and masseter muscle rigidity on exposure to succinylcholine chloride and halothane, but because of rapid recognition of the condition and discontinuation of the procedure, the potentially lethal complications of malignant hyperthermia did not develop." | 3.66 | Suspected malignant hyperthermia in a strabismus patient. A case report. ( Dodd, MJ; Phattiyakul, P; Silpasuvan, S, 1981) |
| "The incidence of Porcine Stress Syndrome (PSS), determined by halothane screening, and parameters of muscle quality and carcass leanness were studied in 108 pigs from a larger population of 658 pigs of Pietrain (P), Minnesota No." | 3.66 | Porcine stress syndrome and postmortem muscle characteristics of two purebreds and three specific terminal crosses. ( Addis, PB; Kukoyi, EA; Martin, FB; McGrath, CJ; Rempel, WE, 1981) |
| "In a study of human malignant hyperpyrexia-susceptible muscle a comparison between pancuronium and methylprednisolone showed that both drugs produced qualitatively similar depression of the halothane-induced muscle contracture." | 3.65 | Anaesthesia for patients susceptible to malignant hyperpyrexia. A study of pancuronium and methylprednisolone. ( Cain, PA; Ellis, FR, 1977) |
| " Using muscle from patients susceptible to malignant hyperpyrexia in vitro, it has been demonstrated that muscle contracture can occur with procaine on its own, and in one patient the halothane-induced contracture was potentiated by procaine." | 3.65 | An evaluation of procaine in the treatment of malignant hyperpyrexia. ( Clarke, IM; Ellis, FR, 1975) |
| "Halothane-induced contractures in isolated muscle fibers from swine susceptible to malignant hyperthermia (MHS) were significantly less when fibers were incubated in KRB plus 6." | 3.65 | Porcine malignant hyperthermia: effect of dantrolene sodium on in-vitro halothane-induced contraction of susceptible muscle. ( Anderson, IL; Jones, EW, 1976) |
| " The treatment (ice packs, treatment of acidosis, glucose-insulin, methylprednisolone, lidocaine, verapamil, muscular relaxation and oxygen breathing) was effective." | 3.65 | [A further case of malignant hyperpyrexia and its treatment with lidocaine, methylprednisolone and verapamil (iproveratril) (author's transl)]. ( Bake, I; Buttazzoni, E; Csongrady, A; Pfänder, C; Schneider, M; Tarmann, H, 1976) |
| "Four carriers of the abnormal trait for malignant hyperpyrexia have been studied to determine the value of the various methods of carrier detection." | 2.64 | Predictive tests for malignant hyperpyrexia. ( Badenhorst, M; Heffron, JJ; Isaacs, H, 1975) |
| "Individuals susceptible to malignant hyperpyrexia have muscle with heightened sensitivity to halothane, caffeine, succinylcholine, potassium chloride, and temperature change." | 2.64 | Identification of susceptibility to malignant hyperpyrexia. ( Denborough, MA; Moulds, RF, 1974) |
| "Malignant hyperthermia is a hypermetabolic syndrome that appears in susceptible patients after exposure to certain anaesthetic drugs (succinylcholine, inhalation anaesthetics)." | 2.55 | Clinical protocol for the management of malignant hyperthermia. ( Alsina, E; Del Blanco, B; Domínguez, A; García, A; Guerrero, JL; Kollmann-Camaiora, A; Yepes, MJ, 2017) |
| "DNA-based diagnosis for malignant hyperthermia (MH) is an attractive proposition, because it could replace the invasive and morbid caffeine-halothane/in vitro contracture tests of skeletal muscle biopsy tissue." | 2.50 | DNA testing for malignant hyperthermia: the reality and the dream. ( Stowell, KM, 2014) |
| "In human muscle fibers from malignant hyperthermia susceptible patients, such Ca(2+) waves occur when 1mM halothane is applied at physiological [Mg(2+)](i)." | 2.44 | Defective Mg2+ regulation of RyR1 as a causal factor in malignant hyperthermia. ( Duke, AM; Steele, DS, 2007) |
| "The problem of malignant hyperthermia may become worse in the near future due to changes in the population brought about by immigration." | 2.44 | [Anesthesia in malignant hyperthermia]. ( Ortiz Gómez, JR, 2008) |
| "When malignant hyperthermia-does occur in the operating room, prompt recognition and treatment usually prevent a potentially fatal outcome." | 2.40 | Malignant hyperthermia. ( Adnet, P; Ben Abraham, R; Glauber, V; Perel, A, 1998) |
| "The muscle disease malignant hyperthermia is a disorder of intracellular free Ca2+ regulation in both humans and pigs." | 2.38 | Current views of the molecular basis of the malignant hyperthermia syndrome. ( Heffron, JJ; McCarthy, TV, 1990) |
| "Masseter spasm is often associated with severe rhabdomyolysis in patients with muscle dystrophy, especially Duchenne's dystrophy." | 2.38 | [Clinical features of malignant hyperthermia crisis]. ( Cornet, C; Laxenaire, MC; Moeller, R, 1989) |
| "Dantrolene median dose was 50 (25-400) and 200 (25-400) mg·day -1 in responders and nonresponders, respectively." | 1.91 | Oral Dantrolene for Myopathic Symptoms in Malignant Hyperthermia-Susceptible Patients: A 25-Year Retrospective Cohort Study of Adverse Effects and Tolerability. ( Ibarra Moreno, CA; Jungbluth, H; Kraeva, N; Riazi, S; Voermans, NC; Zvaritch, E, 2023) |
| "Most patients with malignant hyperthermia susceptibility diagnosed by the in vitro caffeine-halothane contracture test (CHCT) develop excessive force in response to halothane but not caffeine (halothane-hypersensitive)." | 1.91 | Distinct pathophysiological characteristics in developing muscle from patients susceptible to malignant hyperthermia. ( Figueroa, L; Ibarra-Moreno, CA; Kraeva, N; Manno, C; Riazi, S; Rios, E; Tammineni, ER, 2023) |
| "The variable clinical presentation of malignant hyperthermia (MH), a disorder of calcium signalling, hinders its diagnosis and management." | 1.51 | Abnormal calcium signalling and the caffeine-halothane contracture test. ( Figueroa, L; Kraeva, N; Manno, C; Riazi, S; Ríos, E; Toro, S, 2019) |
| "Individuals genetically susceptible to malignant hyperthermia (MH) exhibit hypermetabolic reactions when exposed to volatile anaesthetics." | 1.51 | Permeabilised skeletal muscle reveals mitochondrial deficiency in malignant hyperthermia-susceptible individuals. ( Allen, PD; Boyle, JP; Chang, L; Daly, C; Hopkins, PM; Miller, DM; Shaw, MA, 2019) |
| "Hydrogen sulfide is an endogenous gasotransmitter and its mechanism of action involves activation of ATP-sensitive K(+) channels and phosphodiesterase inhibition." | 1.43 | Cystathionine β-synthase-derived hydrogen sulfide is involved in human malignant hyperthermia. ( Andria, B; Attanasio, C; Bucci, M; Calderone, V; Cantalupo, A; Cirino, G; Di Martino, A; Ianaro, A; Mancini, A; Panza, E; Savoia, G; Vellecco, V, 2016) |
| "Adenosine accumulation was markedly increased in malignant hyperthermia-susceptible lymphocytes compared with controls reflecting higher than normal adenosine 5'-triphosphate degradation in the malignant hyperthermia-susceptible cells." | 1.42 | Is lymphocyte adenosine a diagnostic marker of clinical malignant hyperthermia? A pilot study. ( Bina, S; Bünger, R; Capacchione, J; Muldoon, S; Munkhuu, B, 2015) |
| "If succinylcholine was not given, MH onset was shorter during sevoflurane anesthesia than during desflurane or isoflurane." | 1.40 | Anesthetic drugs and onset of malignant hyperthermia. ( Brandom, BW; Visoiu, M; Wieland, K; Young, MC, 2014) |
| "Several malignant hyperthermia-associated neuromuscular diseases are associated with an altered connective tissue composition." | 1.40 | Contractile elements in muscular fascial tissue - implications for in-vitro contracture testing for malignant hyperthermia. ( Hoppe, K; Jäger, H; Klingler, W; Lehmann-Horn, F; Schleip, R, 2014) |
| "The clinical symptoms resemble malignant hyperthermia (MH), which may lead to mistreatment of the patient." | 1.39 | In vitro muscle contracture investigations on the malignant hyperthermia like episodes in myotonia congenita. ( Adolph, O; Chaiklieng, S; Hoppe, K; Jurkat-Rott, K; Klingler, W; Lehmann-Horn, F, 2013) |
| "Sevoflurane is a known triggering agent of malignant hyperthermia (MH)." | 1.39 | Sevoflurane is less sensitive than halothane for in vitro detection of malignant hyperthermia susceptibility. ( Heiderich, S; Johannsen, S; Klingler, W; Roewer, N; Schneiderbanger, D; Schuster, F, 2013) |
| "Halothane was the strongest discriminator for malignant hyperthermia in the in-vitro contracture tests." | 1.37 | In-vitro contracture testing for susceptibility to malignant hyperthermia: can halothane be replaced? ( Anetseder, M; Kranke, P; Metterlein, T; Roewer, N; Schuster, F, 2011) |
| "Identifying patients predisposed to malignant hyperthermia is done through the Ca-induced Ca release test in Japan." | 1.37 | Analysis of human cultured myotubes responses mediated by ryanodine receptor 1. ( Hamada, H; Kawamoto, M; Kobayashi, M; Migita, T; Mukaida, K; Yuge, O, 2011) |
| "Halothane was discontinued after the administration of 0." | 1.37 | Comparison of the therapeutic effectiveness of a dantrolene sodium solution and a novel nanocrystalline suspension of dantrolene sodium in malignant hyperthermia normal and susceptible pigs. ( Becker, S; Burmester, S; Gerbershagen, MU; Kröner, L; Lenz, D; Schütte, JK; Starosse, A; Wappler, F, 2011) |
| "To diagnose malignant hyperthermia (MH) susceptibility, muscle bundles are exposed to halothane and caffeine." | 1.37 | Sevoflurane as a potential replacement for halothane in diagnostic testing for malignant hyperthermia susceptibility: results of a preliminary study. ( Anetseder, M; Hartung, E; Metterlein, T; Roewer, N; Schuster, F, 2011) |
| "In vitro contracture testing to diagnose malignant hyperthermia (MH) susceptibility requires a muscle biopsy, which may be associated with severe side effects for the patient." | 1.35 | An in-vivo metabolic test for detecting malignant hyperthermia susceptibility in humans: a pilot study. ( Anetseder, M; Kranke, P; Metterlein, T; Muellenbach, RM; Negele, S; Roewer, N; Schuster, F; Schwemmer, U, 2008) |
| " Reproducible shifts in the dose-response of skeletal muscle to caffeine and halothane are the basis of the current in vitro diagnostic caffeine-halothane contracture test." | 1.33 | Effects of caffeine, halothane, and 4-chloro-m-cresol on skeletal muscle lactate and pyruvate in malignant hyperthermia-susceptible and normal swine as assessed by microdialysis. ( Bina, S; Bünger, R; Cowan, G; Karaian, J; Mongan, P; Muldoon, S, 2006) |
| " MH susceptibility leads to a leftward shift of the dose-response curve for IM lactate after local injection of halothane and caffeine." | 1.33 | The dose-response relationship and regional distribution of lactate after intramuscular injection of halothane and caffeine in malignant hyperthermia-susceptible pigs. ( Anetseder, M; Hager, M; Müller, R; Roewer, N; Schöll, H; Schuster, F, 2006) |
| "We report the first case of malignant hyperthermia, verified by caffeine-halothane contracture test and genetic testing, in a Chinese patient." | 1.33 | Malignant hyperthermia in China. ( Guo, XY; Huang, YG; Luo, AL; Ren, HZ; Wang, YL; Xu, ZH; Ye, TH; Zhang, X, 2006) |
| "Malignant hyperthermia is a pharmacogenetic disorder affecting humans, dogs, pigs, and horses." | 1.33 | Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse. ( Allen, PD; Esteve, E; Goth, S; Lopez, JR; Matthaei, KI; Pessah, IN; Riehl, J; Yang, T, 2006) |
| " The use of high resolution fluorescence microscopy methods in combination with spatio-temporal mathematical models allows the effects of volatile anesthetics on functional clusters of ryanodin receptors in mammalian skeletal muscle fibers to be studied in situ for the first time." | 1.32 | [High resolution fluorescence microscopy in combination with mathematical modelling. First evidence of sub-cellular anesthetic effects on Ca2+ sparks in situ]. ( Both, M; Fink, RH; Graf, BM; Martin, E; Sinner, B; Uttenweiler, D; Zink, W, 2003) |
| "To determine whether malignant hyperthermia (MH) susceptibility in a Canadian pedigree is associated with a mutation in the ryanodine receptor subtype 1 (RYR1) gene, the complete RYR1 transcript obtained from the leukocytes of one MH-susceptible family member was sequenced, using a newly developed protocol." | 1.32 | Detection of a novel ryanodine receptor subtype 1 mutation (R328W) in a malignant hyperthermia family by sequencing of a leukocyte transcript. ( Du, G; Kraev, A; Kraev, N; Loke, JC; MacLennan, DH; Patel, L; Sharma, P, 2003) |
| "The diagnosis of susceptibility to malignant hyperthermia (MH) is currently performed on muscle biopsies subjected to halothane-caffeine in vitro contracture tests (IVCTs)." | 1.32 | Comparative analysis of in vitro contracture tests with ryanodine and a combination of ryanodine with either halothane or caffeine: a comparative investigation in malignant hyperthermia. ( Bendahan, D; Cozzone, PJ; Ghattas, B; Guis, S; Kozak-Ribbens, G; Lunardi, J; Mattei, JP; Monnier, N, 2004) |
| "The halothane-induced increase in [Ca(2+)](i) differed significantly between the three diagnostic groups." | 1.31 | Phenotyping malignant hyperthermia susceptibility by measuring halothane-induced changes in myoplasmic calcium concentration in cultured human skeletal muscle cells. ( Censier, K; Girard, T; Mueller, CR; Treves, S; Urwyler, A; Zorzato, F, 2002) |
| "The diagnostic outcomes of tests for malignant hyperthermia susceptibility were compared between two laboratories by using muscle tissue from the same patients." | 1.31 | Between-center variability of results of the in vitro contracture test for malignant hyperthermia susceptibility. ( Bendixen, D; Islander, G; Ording, H; Ranklev-Twetman, E, 2000) |
| "Anesthetic-induced malignant hyperthermia (MH) in humans and pigs is associated with dramatic alterations in cardiac function." | 1.31 | Altered expression of cardiac myosin isozymes associated with the malignant hyperthermia genotype in swine. ( Jiang, MJ; Liou, YM; Wu, MC, 2000) |
| "Central core disease (CCD) and nemaline myopathy (NM) are congenital myopathies for which differential diagnosis is often based on the presence either of cores or rods." | 1.31 | An autosomal dominant congenital myopathy with cores and rods is associated with a neomutation in the RYR1 gene encoding the skeletal muscle ryanodine receptor. ( Fardeau, M; Lerale, J; Lunardi, J; MacLennan, DH; Monnier, N; Nivoche, Y; Qi, D; Romero, NB, 2000) |
| "Xenon 70% did not cause an increase in baseline tension of any MH-susceptible muscle specimen in contrast to halothane and caffeine." | 1.31 | Xenon does not induce contracture in human malignant hyperthermia muscle. ( Baur, CP; Froeba, G; Georgieff, M; Jurkat-Rott, K; Klingler, W; Lehmann-Horn, F; Marx, T; Schoch, E, 2000) |
| "The determination of susceptibility to malignant hyperthermia (MH) by genetic investigation is a controversial issue because of the genetic heterogeneity of this disorder." | 1.31 | Homozygous and heterozygous Arg614Cys mutations (1840C-->T) in the ryanodine receptor gene co-segregate with malignant hyperthermia susceptibility in a German family. ( Deutrich, C; Froster, UG; Olthoff, D; Rueffert, H; Thamm, B, 2001) |
| " MHEh muscles revealed a dose-response curve similar to that found in MHN specimens." | 1.30 | Classification of malignant hyperthermia-equivocal patients by 4-chloro-M-cresol. ( Bittner, RE; Fricker, R; Gilly, H; Kress, HG; Musat, I; Steinbereithner, K, 1997) |
| "Chlorocresol was demonstrated to be a potent activator of Ca++ release from skeletal muscle sarcoplasmic reticulum." | 1.30 | [Effect of chlorocresol vs caffeine on muscle contracture in malignant hyperthermia susceptible patients]. ( Adnet, PJ; Ben-Abraham, R; Haudcoeur, G; Krivosic-Horber, RM; Perel, A, 1997) |
| "The association between malignant hyperthermia (MH) and neuromuscular disorders is controversial." | 1.30 | Dystrophin deficient mdx muscle is not prone to MH susceptibility: an in vitro study. ( Bittner, RE; Gilly, H; Mader, N, 1997) |
| "Malignant hyperthermia is a main cause of death during general anesthesia, particularly in children." | 1.30 | A rat model of spontaneous myopathy and malignant hyperthermia. ( File, SE; Gonzalez, LE; Gregson, NA; Meléndez-Vásquez, CV, 1998) |
| "The delayed onset of malignant hyperthermia after delivery of halothane is unusual and for successful treatment careful monitoring and rapid and aggressive therapy are needed." | 1.30 | Delayed onset malignant hyperthermia in two pigs. ( Brodbelt, DC; Taylor, PM, 1998) |
| " When co-administered in low dosage with halothane, the drug prevented initiation of the MH syndrome in four of eight pigs and attenuated its progress in the remainder." | 1.30 | Eltanolone (5-beta-pregnanolone) does not trigger, and attenuates halothane triggering of, malignant hyperthermia in malignant hyperthermia susceptible swine. ( Dyer, RA; Harrison, GG; James, MF; Llewellyn, RL, 1999) |
| "Regulation of muscle contraction is abnormal in Thoroughbreds with RER." | 1.30 | Abnormal regulation of muscle contraction in horses with recurrent exertional rhabdomyolysis. ( Balog, EM; Gallant, EM; Lentz, LR; Mickelson, JR; Valberg, SJ, 1999) |
| "Xenon is a noble gas with anesthetic properties currently under investigation for use in humans." | 1.30 | Xenon does not trigger malignant hyperthermia in susceptible swine. ( Baeder, S; Baur, C; Calzia, E; Eichinger, HM; Froeba, G; Georgieff, M; Marx, T; Pazhur, J; Radermacher, P, 1999) |
| "Anaesthesia-induced malignant hyperthermia (MH) may be caused by specific gene defects in the skeletal muscle ryanodine receptor." | 1.29 | Genotype and phenotype relationships for mutations in the ryanodine receptor in patients referred for diagnosis of malignant hyperthermia. ( Fletcher, JE; Hubert, M; Levitt, RC; Rosenberg, H; Tripolitis, L; Vita, GM, 1995) |
| "During human and porcine malignant hyperthermia (MH), cardiac dysrhythmias and altered myocardial function can be observed." | 1.29 | Abnormal action potential responses to halothane in heart muscle isolated from malignant hyperthermia-susceptible pigs. ( Greim, C; Roewer, N; Rumberger, E; Schulte am Esch, J, 1995) |
| "During halothane-induced malignant hyperthermia (MH), plasma levels of serotonin (5-hydroxytryptamine, 5-HT) increase in pigs." | 1.29 | Lack of prophylactic or therapeutic efficacy of 5-HT2A receptor antagonists in halothane-induced porcine malignant hyperthermia. ( Gerdes, C; Löscher, W; Richter, A, 1994) |
| "Masseter muscle rigidity was defined clinically by the transient inability to distract the mandible from the maxilla such that the mouth could not be opened or could only be opened with force." | 1.29 | The incidence of masseter muscle rigidity after succinylcholine in infants and children. ( Burrows, FA; Carr, AS; Creighton, RE; Lazzell, VA; Lerman, J, 1994) |
| "The halothane test was performed under different conditions in 10 halothane-sensitive growing pigs (Landrace, line 01)." | 1.29 | [The effect of anesthesia, of an alpha or beta adrenergic blockade in conscious and of adrenaline in anesthetized halothane-positive swine on hematologic and metabolic parameters in the blood during the course of halothane exposure]. ( Gürtler, H; Neubert, E, 1994) |
| "Malignant hyperpyrexia is an inherited disorder of skeletal muscle characterized by intermittent hypermetabolic crises, usually triggered by anaesthetic agents." | 1.29 | Rhabdomyolysis and acute renal failure in unsuspected malignant hyperpyrexia. ( Burns, AP; Hall, G; Hopkins, PM; Pusey, CD, 1993) |
| "He was treated for malignant hyperthermia." | 1.29 | A hypermetabolic reaction during anaesthesia and surgery. A case report. ( Hopkins, D; Shipton, EA, 1993) |
| "Malignant hyperthermia was not reproducibly induced by halothane anesthesia." | 1.29 | In vivo 31P NMR spectroscopy studies of halothane induced porcine stress syndrome. No effect of C-phenyl N-tert-butyl nitrone (PBN). ( Gareau, PJ; Janzen, EG; Stewart, WA; Towner, RA, 1993) |
| "Halothane was withdrawn after a 20% drop in PCr." | 1.29 | Metabolic response to halothane in piglets susceptible to malignant hyperthermia: an in vivo 31P-NMR study. ( Decanniere, C; Geers, R; Van Hecke, P; Vanstapel, F; Villé, H, 1993) |
| "In dantrolene-treated animals, EEG total power and median frequency increased within 5 min." | 1.29 | Improvement of brain electrical activity during treatment of porcine malignant hyperthermia with dantrolene. ( Hoffman, WE; Kochs, E; Schulte am Esch, J, 1993) |
| "The identification of disposition for malignant hyperthermia (MH) is performed by the halothane-caffeine contracture test in skeletal muscle." | 1.29 | [High purity ryanodine for in vitro diagnosis of malignant hyperthermia]. ( Lenzen, C; Roewer, N; Rumberger, R; Scholz, J; Schulte am Esch, J; Steinfath, M; Wappler, F, 1993) |
| "Malignant hyperthermia is a seemingly rare genetic myopathy." | 1.29 | Malignant hyperthermia in the otology patient: the UCLA experience. ( Blackwell, KE; Wackym, PA, 1994) |
| "Halothane in Krebs was assayed by high pressure liquid chromatography." | 1.29 | Caffeine-halothane accuracy in MH testing. ( Antognini, JF; Chun, K; Gronert, GA; Hwang, F, 1995) |
| "Ritanserin did not cause any significant changes of IP levels compared to the basal concentrations in MHS and MHN pigs." | 1.29 | Effects of the 5-HT2 receptor antagonist ritanserin on halothane-induced increase of inositol phosphates in porcine malignant hyperthermia. ( Löscher, W; Richter, A; Scholz, J; Tonner, PH; Wappler, F, 1996) |
| "To investigate a possible link of malignant hyperthermia to capture myopathy, between June 1990 and July 1993 we anesthetized four black-tailed deer (Odocoileus hemionus columbianus) and challenged them with halothane and succinylcholine." | 1.29 | Evaluation for malignant hyperthermia susceptibility in black-tailed deer. ( Antognini, JF; Eisele, PH; Gronert, GA, 1996) |
| "1." | 1.28 | W-7, a calmodulin antagonist, and contracture of malignant hyperthermia susceptible skeletal muscle. ( Holland, M; Lee, JC; Williams, JH, 1992) |
| "Isoflurane has a lesser ability than halothane to induce contracture in malignant hyperthermia (MH) muscle in vitro." | 1.28 | Effect of Bay K 8644 on the magnitude of isoflurane and halothane contracture of skeletal muscle from patients susceptible to malignant hyperthermia. ( Adamantidis, MM; Adnet, PJ; Haudecoeur, G; Imbenotte, M; Krivosic-Horber, RM; Reyford, H, 1992) |
| "2." | 1.28 | Propofol anaesthesia in malignant hyperpyrexia susceptible swine. ( Denborough, MA; Foster, PS; Hopkinson, KC, 1992) |
| "In vitro muscle contracture tests for malignant hyperthermia screening are routinely performed using standardized protocols." | 1.28 | Effect of halothane equilibration kinetics on in vitro muscle contractures for malignant hyperthermia screening. ( Censier, K; Drewe, J; Funk, B; Urwyler, A, 1992) |
| "These results suggest that (i) the malignant hyperthermia syndrome is not directly related to the polar heads of phospholipids and (ii) dantrolene counteracts unspecifically the disturbing effect of halothane at the lipid level." | 1.28 | 31P NMR and freeze fracture studies of sarcoplasmic reticulum membranes from normal and malignant hyperthermic pigs: effect of halothane and dantrolene. ( Dufourc, EJ; Gaillard, S; Renou, JP; Rock, E; Vignon, X, 1992) |
| "Halothane is a potent inhaled anesthetic that is used extensively in veterinary practice." | 1.28 | Precautions when using halothane. ( Gleed, R, 1992) |
| "Pre-treatment with ryanodine did not change the calcium signal brought about by halothane or ionomycin." | 1.28 | [Effects of halothane, caffeine and ryanodine on the intracellular calcium store in blood mononuclear cells]. ( Endo, M; Iino, M; Kawana, Y; Oyamada, H, 1992) |
| "Normal and malignant hyperthermia membranes from sarcolemma as well as from sarcoplasmic reticulum did not show significant differences near the polar heads of the phospholipidic bilayer." | 1.28 | Membrane properties of the sarcolemma and sarcoplasmic reticulum of pigs susceptible to malignant hyperthermia. Action of halothane. ( Rock, E; Thomas, MA; Viret, J, 1991) |
| "The mechanisms causing the malignant hyperthermia (MH) syndrome are related to a malfunction of intracellular Ca2+ homeostasis and can be prevented or reversed by dantrolene." | 1.28 | EU 4093 decreases intracellular [Ca2+] in skeletal muscle fibers from control and malignant hyperthermia-susceptible swine. ( Allen, PD; López, JR; Ryan, JF; Sánchez, V; Sreter, FA, 1992) |
| "Until our malignant hyperthermia diagnostic center was opened, such tests could not be performed in Israel." | 1.28 | [In vitro diagnosis of malignant hyperpyrexia syndrome]. ( Eldar, I; Glauber, V; Goldberg, G; Perel, A, 1991) |
| "Halothane was dosed by chromatography in the three compartments of a bath for isolated organs with a muscular fiber during steady concentrations were given and after wash out." | 1.28 | [Malignant hyperthermia: halothane kinetics in a study model of muscular contraction. Head space determination and comparison with a mathematical model]. ( Guevart, E; Haguenoer, JM; Imbenotte, M; Theunynck, D, 1991) |
| "The greater sensitivity of malignant hyperthermia muscle to halothane can be explained by elevated fatty acid production." | 1.28 | Fatty acids markedly lower the threshold for halothane-induced calcium release from the terminal cisternae in human and porcine normal and malignant hyperthermia susceptible skeletal muscle. ( Fletcher, JE; Mayerberger, S; Rosenberg, H; Tripolitis, L; Yudkowsky, M, 1991) |
| "This report describes a cardiac arrest that occurred in a 4-month-old infant during induction of anesthesia." | 1.28 | [Cardiac arrest during anesthesia induction with halothane and succinylcholine in an infant. Massive hyperkalemia and rhabdomyolysis in suspected myopathy and/or malignant hyperthermia]. ( Bachour, H; Mehler, J; Simons, F; Wolpers, K, 1991) |
| "Platelets from normal and malignant hyperthermia (MH)-susceptible pigs were evaluated for differences in 45calcium uptake in the absence or presence of caffeine (2-16 mM), halothane (0." | 1.28 | Calcium handling by platelets from normal and malignant hyperthermia-susceptible pigs. ( Bonk, KR; Brooks, RR; Carpenter, JF; Miller, KE, 1991) |
| "The inheritance of malignant hyperthermia susceptibility is thought to be autosomal dominant and the incidence could be as high as 1:10,000." | 1.28 | [Diagnosis of susceptibility for malignant hyperthermia using in-vitro muscle contraction testing in Switzerland]. ( Censier, K; Drewe, J; Frei, F; Rothenbühler, JM; Seeberger, MD; Urwyler, A, 1991) |
| "Based on studies in swine, the malignant hyperthermia syndrome has been postulated to result from an enhanced sensitivity (low threshold) of the Ca2(+)-induced Ca2(+)-release process." | 1.28 | Fatty acids modulate calcium-induced calcium release from skeletal muscle heavy sarcoplasmic reticulum fractions: implications for malignant hyperthermia. ( Beech, J; Conti, PA; Erwin, K; Fletcher, JE; Hanson, S; Rosenberg, H; Tripolitis, L, 1990) |
| "Ten swine susceptible to malignant hyperthermia (MH) were triggered into MH episodes via the inhalation of halothane, and azumolene was effective in terminating all of the MH episodes." | 1.28 | Azumolene reverses episodes of malignant hyperthermia in susceptible swine. ( Dershwitz, M; Sréter, FA, 1990) |
| " In six MH(-) patients with previous masseter muscle rigidity, no adverse reactions occurred in response to volatile anesthetic agents." | 1.28 | Safety of general anesthesia in patients previously tested negative for malignant hyperthermia susceptibility. ( Allen, GC; Fletcher, JE; Rosenberg, H, 1990) |
| "Although an association between malignant hyperthermia (MH) and congenital abnormalities has been recorded, no prospective study has been attempted to investigate this relationship." | 1.28 | An association between certain congenital abnormalities and the malignant hyperthermia trait. ( Gericke, GS; Isaacs, H, 1990) |
| "To determine whether a malignant hyperthermia (MH) episode could nevertheless be provoked by a more rigorous challenge, both genetically MHS (Pietrain) and normal (Yorkshire) 5-wk-old piglets were exposed to a combined halothane-succinylcholine challenge." | 1.28 | Halothane sensitivity of young pigs in vivo and in vitro. ( Fay, RS; Gallant, EM, 1990) |
| "Pretreatment with diltiazem modified an MH response." | 1.28 | Effect of diltiazem on porcine malignant hyperpyrexia induced by suxamethonium and halothane. ( Denborough, MA; Foster, PS; Hopkinson, KC, 1989) |
| "Halothane-induced malignant hyperthermia (MH) is thought to result from a defect in the regulation of cytosolic calcium concentration in MH-susceptible (MHS) skeletal muscle." | 1.28 | Porcine malignant hyperthermia: halothane effects on force generation in skeletal muscles. ( Gallant, EM; Goettl, VM, 1989) |
| "Blood platelets from malignant hyperthermia patients share the same defect as skeletal muscle." | 1.28 | Sensitivity of the adenine nucleotide metabolism of platelets from malignant hyperthermia patients to halothane. ( Büttner, C; Hofmann, JG; Till, U, 1989) |
| "Mean onset time of malignant hyperthermia on exposure to halothane alone was 7." | 1.28 | The screening of propofol in MHS swine. ( Harrison, GG; Raff, M, 1989) |
| "Halothane was then discontinued, an oxygen flow rate of 12 litres per minute was begun, and continuous measurements were made until the halothane concentration became undetectable." | 1.28 | Malignant hyperthermia and the clean machine. ( Keon, TP; McGraw, TT, 1989) |
| " In contrast, propranolol shifted the caffeine dose-response curve to the right and significantly increased the caffeine threshold in the MHS group." | 1.28 | Influence of propranolol on the in vitro response to caffeine and halothane in malignant hyperthermia-susceptible muscle. ( Ording, H, 1989) |
| "Midazolam is a water soluble benzodiazepine of interest to the anaesthetist for use as a premedicant and for induction of anaesthesia." | 1.27 | Effects of midazolam on directly stimulated muscle biopsies from control and malignant hyperthermia positive patients. ( Fletcher, JE; Hilf, M; Rosenberg, H, 1984) |
| "The caffeine test was positive in 68% of MHS patients, 0." | 1.27 | Investigation of malignant hyperthermia in Denmark and Sweden. ( Fletcher, R; Ording, H; Ranklev, E, 1984) |
| "A European Malignant Hyperpyrexia Group has been formed to facilitate exchange of information between centres performing in vitro muscle testing for malignant hyperpyrexia susceptibility." | 1.27 | A protocol for the investigation of malignant hyperpyrexia (MH) susceptibility. The European Malignant Hyperpyrexia Group. ( , 1984) |
| "Purebred Pietrain malignant hyperthermia (MH)-susceptible pigs (n = 102) were subjected to halothane (0%, 1%, 2%, 3%, 4%, and 5%) in oxygen." | 1.27 | Halothane testing for malignant hyperthermia in swine: dose-response effects. ( Lee, JC; McGrath, CJ; Rempel, WE, 1984) |
| "Succinylcholine was administered by infusion to halothane-anesthetized ponies to determine dosage requirements for surgical relaxation up to 3 hours' duration." | 1.27 | Succinylcholine infusion associated with hyperthermia in ponies anesthetized with halothane. ( Hildebrand, SV; Howitt, GA, 1983) |
| "Verapamil was not effective in preventing or delaying a MH reaction." | 1.27 | Noneffectiveness of verapamil in preventing halothane-induced malignant hyperthermia in susceptible swine. ( Lee, JC; McGrath, CJ; Rempel, WE, 1984) |
| "in an attempt to induce malignant hyperthermia." | 1.27 | Failure to induce malignant hyperthermia in myotonic goats. ( Gronert, GA; Lambert, EH; Newberg, LA, 1983) |
| "Since the cellular defect of malignant hyperthermia (MH) may occur in tissues other than muscle and since platelets share certain contractile characteristics with muscle cells, testing platelets has been suggested as a way to diagnose susceptibility to MH." | 1.27 | Halothane-induced ATP depletion in platelets from patients susceptible to malignant hyperthermia and from controls. ( Giger, U; Kaplan, RF, 1983) |
| "Dantrolene was shown to inhibit the halothane-induced calcium release." | 1.27 | Calcium-induced Ca2+ release from sarcoplasmic reticulum of pigs susceptible to malignant hyperthermia. The effects of halothane and dantrolene. ( Gronert, GA; Ohnishi, ST; Taylor, S, 1983) |
| "Though a malignant hyperthermia (MH) crisis is still a critical event during general anesthesia, recent developments in prophylaxis and treatment should help in avoiding fatal episodes." | 1.27 | [Diagnosis of susceptibility to malignant hyperthermia using the in vitro contracture test]. ( Klein, W; Küther, G; Lehmann-Horn, F; Pongratz, D; Spiess-Kiefer, C, 1987) |
| "Myoballs from a man susceptible to malignant hyperthermia (MH) gave the same results as the controls indicating that the halothane effect on the action potential of MH-susceptible muscle are not mediated by a specific effect on the sodium channels." | 1.27 | Differential effects of halothane on adult and juvenile sodium channels in human muscle. ( Rüdel, R; Ruppersberg, JP, 1988) |
| "Vecuronium was studied in eight malignant hyperthermia (MH) susceptible pigs for its potential to either trigger or prevent MH." | 1.27 | Vecuronium and porcine malignant hyperthermia. ( Buzello, W; Chandra, P; Dozier, SE; Watkins, ML; Williams, CH, 1985) |
| "The halothane-induced increase in [Ca2+]i required extracellular calcium ions." | 1.27 | Anaesthetic-induced increase in ionised calcium in blood mononuclear cells from malignant hyperthermia patients. ( Britt, BA; Elliott, ME; Frodis, W; Klip, A; Pegg, W; Scott, E, 1987) |
| "Malignant hyperthermia is a potentially lethal syndrome that can be triggered by inhaled anesthetics." | 1.27 | Preparation of anesthesia machines for patients susceptible to malignant hyperthermia. ( Beebe, JJ; Sessler, DI, 1988) |
| "Malignant hyperthermia is a seemingly rare genetic myopathy." | 1.27 | Malignant hyperthermia in plastic surgery. ( Abdul-Rasool, IH; Dubrow, TJ; Lesavoy, MA; Wackym, PA, 1988) |
| "Animals were identified as porcine malignant hyperthermia susceptible by halothane testing and were slaughtered at 90 kg of body weight." | 1.27 | Halothane induced vasomotion of coronary, renal and iliac arterial rings in malignant hyperthermia susceptible swine. ( DeRoth, L; Héon, H; Nadeau, S, 1988) |
| "1." | 1.27 | Calmodulin-antagonist drugs and porcine malignant hyperpyrexia. ( Collins, SP; Denborough, MA; White, MD, 1988) |
| "The association of malignant hyperthermia (MH) with neuromuscular disorders has been recognized since 1970." | 1.27 | Halothane-caffeine contracture testing in neuromuscular diseases. ( Fletcher, JE; Heiman-Patterson, TD; Rosenberg, H; Tahmoush, AJ, 1988) |
| "We have investigated in malignant hyperthermia susceptible swine in vivo the effects on halothane initiation of the MH syndrome and on the established syndrome of five calcium channel blocking drugs--nifedipine, nisoldipine, diltiazem, verapamil and flunarazine." | 1.27 | The effects of calcium channel blocking drugs on halothane initiation of malignant hyperthermia in MHS swine and on the established syndrome. ( Harrison, GG; Morrell, DF; Wright, IG, 1988) |
| "Arthrogryposis multiplex congenita has been linked with malignant hyperthermia." | 1.27 | Anaesthesia for patients with arthrogryposis multiplex congenita: what is the risk of malignant hyperthermia? ( Baines, DB; Douglas, ID; Overton, JH, 1986) |
| "The acute malignant hyperthermia crisis appears to be mediated by a sudden and sustained rise in the concentration of sarcoplasmic calcium, leading to a prolonged muscle contraction." | 1.27 | Abnormal relaxation rates in subjects susceptible to malignant hyperthermia. ( Henriksson, KG; Lennmarken, C; Rutberg, H, 1987) |
| "The halothane-mediated increase in cytoplasmic ionized Ca2+ required extracellular Ca2+." | 1.27 | Selective increase in cytoplasmic calcium by anesthetic in lymphocytes from malignant hyperthermia-susceptible pigs. ( Britt, BA; Elliott, ME; Klip, A; Ramlal, T; Walker, D, 1987) |
| "The relationship between neuroleptic malignant syndrome (NMS) and malignant hyperthermia (MH) was investigated using the in vitro skeletal muscle contracture test to screen for MH-susceptibility in NMS patients." | 1.27 | Malignant hyperthermia susceptibility in neuroleptic malignant syndrome. ( Caroff, SN; Fletcher, JE; Heiman-Patterson, TD; Mann, SC; Rosenberg, H, 1987) |
| "In vitro tests for the diagnosis of malignant hyperthermia susceptibility were performed in 105 patients and 20 normal controls according to the protocol of the European MH Group." | 1.27 | In vitro diagnosis of susceptibility to malignant hyperthermia: comparison between dynamic and static halothane and caffeine tests. ( Ording, H; Skovgaard, LT, 1987) |
| "A case of probable crisis of malignant hyperthermia triggered by halothane is reported." | 1.27 | [Carpopedal spasm during anesthesia with halothane: malignant hyperthermia or tetany?]. ( Kancir, CB, 1986) |
| "Two cases of malignant hyperthermia (MH) are presented." | 1.27 | Malignant hyperthermia: clinical course and metabolic changes in two patients. ( Håkanson, E; Rutberg, H, 1986) |
| "Results of this study suggest that malignant hyperthermia is initiated due to a hypersensitive calcium-release mechanism which is inherited in an autosomal, codominant pattern and may be diagnosed using calcium-release sensitivity-tests on isolated sarcoplasmic reticulum." | 1.27 | Porcine malignant hyperthermia susceptibility: hypersensitive calcium-release mechanism of skeletal muscle sarcoplasmic reticulum. ( O'Brien, PJ, 1986) |
| "The familial nature of anaesthetic malignant hyperthermia must lead to the search for susceptibility in other members of the family of a sensitive subject." | 1.27 | [Examination of the family of a patient susceptible to anesthetic malignant hyperthermia]. ( Adnet, P; Guévart, E; Krivosic, I; Krivosic-Horber, R; Theunynck, D, 1986) |
| "The susceptibility of these animals to malignant hyperthermia or the porcine stress syndrome was unknown at the time of the study." | 1.27 | Evaluation of a commercial creatine kinase screening test for malignant hyperthermia (porcine stress syndrome). ( Basrur, PK; McDonell, WN; Seeler, DC, 1986) |
| "To diagnose malignant hyperthermia susceptibility (MHS), caffeine and halothane contracture tests were performed on six patients." | 1.27 | [Detection of peranesthetic malignant hyperthermia by muscle contracture tests and NMR spectroscopy]. ( Gascard, JP; Kozak-Reiss, G; Redouane-Bénichou, K, 1986) |
| "Malignant hyperthermia is a muscle disease characterized by an abnormal response to anaesthetics, stress, and exercise." | 1.27 | Changes in cytoplasmic free calcium caused by halothane. Role of the plasma membrane and intracellular Ca2+ stores. ( Britt, BA; Elliott, ME; Klip, A; Pegg, W; Ramlal, T; Walker, D, 1986) |
| "As found, the pigs affected by the malignant hyperthermia syndrome have thicker muscle fibres in the studied muscles." | 1.27 | [Muscle fibers of pigs sensitive to halothane and resistant to it]. ( Bulla, J; Kulísková, L; Poltársky, J; Uhrín, V, 1985) |
| "The father was found to be malignant hyperpyrexia-susceptible." | 1.27 | Malignant hyperpyrexia and sudden death. ( Fletcher, R; Krantz, P; Ranklev, E, 1985) |
| "No abnormality in malignant hyperpyrexia susceptible muscle was found." | 1.26 | Effect of halothane on adenylate kinase in porcine malignant hyperpyrexia. ( Denborough, MA; Marjanen, LA, 1982) |
| "Controversial aspects of malignant hyperthermia management such as the safety of calcium and catechol inotropes are discussed in relationship to the successful use of cardio-pulmonary bypass in our patient." | 1.26 | Management of a malignant hyperthermia patient during cardiopulmonary bypass. ( Byrick, RJ; Ranganathan, N; Rose, DK, 1982) |
| "However, once malignant hyperthermia developed in susceptibe pigs ATP levels decreased significantly." | 1.26 | A halothane-induced biochemical defect in muscle of normal and malignant hyperthermia-susceptible Landrace pigs. ( Heffron, JJ; Mitchell, G; van Rensburg, AJ, 1980) |
| "Variations in the onset of malignant hyperthermia were observed in five Poland China swine." | 1.26 | Variations in onset of porcine malignant hyperthermia. ( Gronert, GA; Milde, JH, 1981) |
| "Erythrocyte fragility of malignant hyperthermia-susceptible and resistant pigs has been examined as a function of pH and temperature in the absence and presence of halothane and its metabolites." | 1.26 | Influence of pH, temperature, halothane and its metabolites on osmotic fragility of erythrocytes of malignant hyperthermia-susceptible and resistant pigs. ( Heffron, JJ; Mitchell, G, 1981) |
| "Dantrolene dose response was determined twice in each anaesthetized subject, once with thiopentone and subsequently with thiopentone and halothane." | 1.26 | Porcine malignant hyperthermia--failure of dantrolene dose response to diagnose susceptibility (halothane effect). ( Bee, DE; Flewellen, EH; Nelson, TE, 1980) |
| "An exceptionally serious case of malignant hyperthermia in a 17 year old male is presented." | 1.26 | [Malignant hyperthermia. A case report (author's transl)]. ( Rettig, B; Weitz, H, 1980) |
| "This model for malignant hyperpyrexia resembles the naturally occurring disease more closely than several preceding pharmacologic models." | 1.26 | A laboratory animal model for malignant hyperpyrexia. ( Durbin, CG; Rosenberg, H, 1979) |
| "Symptoms of malignant hyperthermia did not occur." | 1.26 | [The effect of halothane anesthesia on the function of the adrenal cortex and some metabolites in the blood plasma of pigs not susceptible to malignant hyperthermia]. ( Dvorák, M, 1979) |
| "Some non-rigid Malignant Hyperthermia Susceptible (MHS) patients have a greater than normal incidence of fractures." | 1.26 | In vivo neutron activation analysis for bone calcium (INVAA) in malignant hyperthermia susceptible patients. ( Britt, BA; Harrison, JE; McNeill, KG, 1979) |
| "In this Research Conference we define malignant hyperthermia, present its brief history, and describe the diagnostic procedures and directions of research in our laboratory." | 1.26 | Malignant hyperthermia: diagnosis, treatment and investigations of a skeletal muscle lesion. ( Flewellen, EH; Nelson, TE, 1979) |
| "A case of malignant hyperthermia in a Black boy is presented." | 1.26 | [Malignant hyperthermia in a black child. A case report]. ( du Toit, PW; Erasmus, FR; Hugo, JM; Muller, FO; Ungerer, MJ; van Velden, DJ, 1978) |
| "We have perfused malignant hyperthermia susceptible and normal isolated pig livers with halothane for one hour." | 1.26 | Perfusion of malignant hyperthermia susceptible and normal isolated pig livers with halothane. ( Britt, BA; Endrenyl, L; Kent, GM; Shandling, B, 1978) |
| "During malignant hyperthermia (MH) induced by halothane and succinylcholine, oxygen consumption (VO2) of whole body, muscle and the splanchnic area was calculated from measurements of blood flow and arteriovenous oxygen content difference." | 1.26 | Porcine malignant hyperthermia: role of skeletal muscle in increased oxygen consumption. ( Gronert, GA; Heffron, JJ; Milde, JH; Theye, RA, 1977) |
| "Two cases of malignant hyperthermia with different clinical courses are reported." | 1.26 | [Report on 2 cases of malignant hyperthermia with different clinical courses]. ( Freiberger, K; Gullotta, F; Helpap, B; Menzel, H, 1976) |
| "In addition to two published cases of malignant hyperthermia (M." | 1.26 | [Mild form of malignant hyperthermia? OR, ABNORMAL REACTION To succinyldicholine?]. ( Hammami, G; Sajons, M; Zinganell, K, 1976) |
| "Experience with eight cases of malignant hyperpyrexia are presented." | 1.26 | Clinical management of malignant hyperpyrexia. ( Krasna, IH; Sonnenklar, N, 1976) |
| "When dantrolene was added to supportive therapy, Vo2, lactate, K+, catecholamines, and temperature decreased, and the course of MH was dramatically slowed and, apparently, reversed." | 1.26 | Dantrolene in porcine malignant hyperthermia. ( Gronert, GA; Milde, JH; Theye, RA, 1976) |
| "Porcine malignant hyperthermia was studied in seven Pietrain pigs under standardized experimental conditions." | 1.26 | Porcine malignant hyperthermia. I: Metabolic and physiological changes. ( Hall, GM; Lister, D; Lucke, JN, 1976) |
| "Halothane 1% was then administered for 1 hr." | 1.25 | Calcium uptake into muscle of pigs susceptible to malignant hyperthermia: in vitro and in vivo studies with and without halothane. ( Britt, BA; Cadman, DL; Endrenyi, L, 1975) |
| "Since it is known that malignant hyperthermia has a familial predilection, it seems very important that clinical, biochemical, and morphological investigations be performed such as CPK estimations and muscular biopsies not only of the patients but also of the relatives in order to rule out this type of latent myopathy." | 1.25 | [Histological, histochemical, and ultrastructural findings in malignant hyperthermia (author's transl)]. ( Gullotta, F; Helpap, B, 1975) |
| "A case of malignant hyperpyrexia with unusual features in a South African negro child is described." | 1.25 | An unusual case of malignant hyperpyrexia. First reported case in a South African negro. ( Carstens, J; Peltz, B, 1975) |
| "In most "malignant hyperpyrexia" families the susceptible patients had either normal or inconsistently raised CPK values." | 1.25 | Evaluation of creatinine phosphokinase in screening patients for malignant hyperpyrexia. ( Clarke, IM; Currie, S; Ellis, FR; Harriman, DG; Modgill, M, 1975) |
| "The methods used to screen patients for malignant hyperpyrexia at present are not sufficiently accurate." | 1.25 | Screening for malignant hyperpyrexia. ( Ellis, FR; Hargreaves, JB; Harriman, DG; Keaney, NP; Kyei-Mensah, K; Mulrooney, PL; Parikh, RK; Sumner, DW; Tyrrell, JH, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 359 (51.14) | 18.7374 |
| 1990's | 217 (30.91) | 18.2507 |
| 2000's | 73 (10.40) | 29.6817 |
| 2010's | 41 (5.84) | 24.3611 |
| 2020's | 12 (1.71) | 2.80 |
| Authors | Studies |
|---|---|
| Saidman, LJ | 1 |
| Bin, X | 1 |
| Wang, B | 1 |
| Tang, Z | 1 |
| Carlson, KJ | 1 |
| Sun, SA | 1 |
| Swan, C | 1 |
| Koenig, M | 1 |
| Derkay, CS | 1 |
| Ibarra Moreno, CA | 3 |
| Kraeva, N | 9 |
| Zvaritch, E | 2 |
| Jungbluth, H | 1 |
| Voermans, NC | 1 |
| Riazi, S | 9 |
| Fu, PH | 1 |
| Ho, CN | 1 |
| Figueroa, L | 3 |
| Manno, C | 2 |
| Ibarra-Moreno, CA | 1 |
| Tammineni, ER | 1 |
| Rios, E | 3 |
| Hopkins, PM | 19 |
| Feng, W | 2 |
| Lopez, JR | 13 |
| Antrobus, S | 1 |
| Zheng, J | 1 |
| Uryash, A | 3 |
| Dong, Y | 1 |
| Beqollari, D | 1 |
| Bannister, RA | 1 |
| Beam, KG | 1 |
| Allen, PD | 12 |
| Pessah, IN | 4 |
| Adams, JA | 1 |
| Biesecker, L | 1 |
| Van Petegem, F | 1 |
| Bojko, B | 1 |
| Vasiljevic, T | 1 |
| Boyaci, E | 1 |
| Roszkowska, A | 1 |
| Koivu, A | 1 |
| Wąsowicz, M | 1 |
| Hanna, A | 1 |
| Hamilton, S | 1 |
| Pawliszyn, J | 1 |
| Yamazawa, T | 1 |
| Kobayashi, T | 1 |
| Kurebayashi, N | 1 |
| Konishi, M | 1 |
| Noguchi, S | 1 |
| Inoue, T | 1 |
| Inoue, YU | 1 |
| Nishino, I | 1 |
| Mori, S | 1 |
| Iinuma, H | 1 |
| Manaka, N | 1 |
| Kagechika, H | 1 |
| Adams, J | 1 |
| Liu, X | 1 |
| Diggle, C | 1 |
| Kakizawa, S | 1 |
| Ikeda, K | 1 |
| Lin, B | 1 |
| Ikemi, Y | 1 |
| Nunomura, K | 1 |
| Nakagawa, S | 1 |
| Sakurai, T | 1 |
| Murayama, T | 1 |
| Choi, RH | 1 |
| Koenig, X | 1 |
| Launikonis, BS | 1 |
| Thompson, SJ | 1 |
| Noseworthy, MD | 1 |
| Rayner, TE | 1 |
| Schneiderman, JE | 1 |
| Cifra, B | 1 |
| Wells, GD | 1 |
| Schiemann, AH | 2 |
| Bjorksten, AR | 1 |
| Gillies, RL | 1 |
| Hockey, BM | 1 |
| Ball, C | 1 |
| Pollock, N | 4 |
| Bulger, T | 2 |
| Stowell, KM | 4 |
| Johannsen, S | 5 |
| Schick, M | 1 |
| Roewer, N | 22 |
| Schuster, F | 12 |
| Türkmeneli, I | 1 |
| Isbary, S | 1 |
| Kaura, V | 2 |
| Diggle, CP | 1 |
| Aboelsaod, EM | 1 |
| Toro, S | 1 |
| Dirksen, RT | 2 |
| Hudig, K | 1 |
| Machon, RG | 1 |
| Woodhead, A | 1 |
| Chang, L | 1 |
| Daly, C | 1 |
| Miller, DM | 1 |
| Boyle, JP | 1 |
| Shaw, MA | 4 |
| Brandom, BW | 5 |
| Bina, S | 7 |
| Wong, CA | 1 |
| Wallace, T | 1 |
| Visoiu, M | 2 |
| Isackson, PJ | 1 |
| Vladutiu, GD | 2 |
| Sambuughin, N | 2 |
| Muldoon, SM | 9 |
| Hoppe, K | 2 |
| Lehmann-Horn, F | 13 |
| Chaiklieng, S | 1 |
| Jurkat-Rott, K | 2 |
| Adolph, O | 1 |
| Klingler, W | 5 |
| Larach, MG | 6 |
| Hu, C | 1 |
| Wijeysundera, D | 1 |
| Massey, C | 1 |
| Orlov, D | 1 |
| Keith, J | 1 |
| Rosen, D | 1 |
| Croul, S | 1 |
| Schneiderbanger, D | 2 |
| Heiderich, S | 1 |
| Young, MC | 1 |
| Wieland, K | 1 |
| Moegele, S | 1 |
| Metterlein, T | 7 |
| Anetseder, M | 10 |
| Altamirano, F | 1 |
| Eltit, JM | 1 |
| Robin, G | 1 |
| Linares, N | 1 |
| Ding, X | 1 |
| Schleip, R | 1 |
| Jäger, H | 1 |
| Capacchione, J | 1 |
| Munkhuu, B | 1 |
| Muldoon, S | 5 |
| Bünger, R | 3 |
| Timmins, MA | 1 |
| Rosenberg, H | 41 |
| Sterling, C | 1 |
| Sagui, E | 1 |
| Montigon, C | 1 |
| Abriat, A | 1 |
| Jouvion, A | 1 |
| Duron-Martinaud, S | 1 |
| Canini, F | 2 |
| Zagnoli, F | 1 |
| Bendahan, D | 4 |
| Figarella-Branger, D | 2 |
| Brégigeon, M | 1 |
| Brosset, C | 1 |
| Vellecco, V | 1 |
| Mancini, A | 1 |
| Ianaro, A | 1 |
| Calderone, V | 1 |
| Attanasio, C | 1 |
| Cantalupo, A | 1 |
| Andria, B | 1 |
| Savoia, G | 1 |
| Panza, E | 1 |
| Di Martino, A | 2 |
| Cirino, G | 1 |
| Bucci, M | 1 |
| Treves, S | 4 |
| Müller, CR | 1 |
| Mögele, S | 1 |
| Kollmann-Camaiora, A | 1 |
| Alsina, E | 1 |
| Domínguez, A | 1 |
| Del Blanco, B | 1 |
| Yepes, MJ | 1 |
| Guerrero, JL | 1 |
| García, A | 1 |
| Hager, M | 2 |
| Muellenbach, RM | 2 |
| Wurmb, T | 1 |
| Wunder, C | 1 |
| Negele, S | 1 |
| Kranke, P | 4 |
| Schwemmer, U | 1 |
| Kaufmann, A | 2 |
| Kraft, B | 3 |
| Michalek-Sauberer, A | 4 |
| Weigl, LG | 3 |
| Mayhew, JF | 3 |
| Mychaskiw, G | 1 |
| Parness, J | 2 |
| Dainese, M | 1 |
| Quarta, M | 1 |
| Lyfenko, AD | 1 |
| Paolini, C | 1 |
| Canato, M | 1 |
| Reggiani, C | 1 |
| Protasi, F | 2 |
| Carpenter, D | 2 |
| Robinson, RL | 3 |
| Quinnell, RJ | 2 |
| Ringrose, C | 2 |
| Hogg, M | 1 |
| Casson, F | 1 |
| Booms, P | 1 |
| Iles, DE | 1 |
| Halsall, PJ | 13 |
| Steele, DS | 5 |
| Finsterer, J | 1 |
| Höftberger, R | 1 |
| Hogan, KJ | 1 |
| Leo, V | 1 |
| Morris, A | 1 |
| Matos, AR | 2 |
| Rumjanek, FD | 1 |
| Amoedo, ND | 1 |
| Cunha, LB | 2 |
| Zapata-Sudo, G | 2 |
| Sudo, RT | 5 |
| Liang, X | 1 |
| Chen, K | 1 |
| Fruen, B | 2 |
| Hu, J | 1 |
| Ma, J | 1 |
| Hu, X | 1 |
| Carmo, PL | 1 |
| Trachez, MM | 1 |
| Cardoso, LA | 1 |
| Aguiar, MI | 1 |
| Abreu, AV | 1 |
| Wang, YL | 3 |
| Luo, AL | 3 |
| Tan, G | 1 |
| Cui, XL | 1 |
| Guo, XY | 3 |
| Duke, AM | 4 |
| Calaghan, SC | 1 |
| Halsall, JP | 1 |
| Urwyler, A | 14 |
| Kobayashi, M | 1 |
| Mukaida, K | 1 |
| Migita, T | 1 |
| Hamada, H | 1 |
| Kawamoto, M | 1 |
| Yuge, O | 1 |
| Schütte, JK | 1 |
| Becker, S | 1 |
| Burmester, S | 1 |
| Starosse, A | 1 |
| Lenz, D | 1 |
| Kröner, L | 1 |
| Wappler, F | 15 |
| Gerbershagen, MU | 2 |
| Hartung, E | 5 |
| Yuen, B | 1 |
| Boncompagni, S | 1 |
| Yang, T | 2 |
| Matthaei, KI | 2 |
| Goth, SR | 1 |
| Franzini-Armstrong, C | 1 |
| Weindlmayr, M | 1 |
| Kress, HG | 3 |
| Steinboeck, F | 1 |
| Lacava, C | 1 |
| Sgaragli, G | 1 |
| Sipos, E | 1 |
| Höller, C | 1 |
| Fusi, F | 1 |
| Sundblom, J | 1 |
| Melberg, A | 1 |
| Rücker, F | 1 |
| Smits, A | 1 |
| Islander, G | 8 |
| Brooks, C | 1 |
| Brown, SL | 1 |
| Ellis, FR | 20 |
| Snoeck, MM | 1 |
| Oosterhof, A | 1 |
| Tangerman, A | 1 |
| Veerkamp, JH | 2 |
| van Engelen, BG | 1 |
| Gielen, MJ | 1 |
| Etchrivi, TS | 4 |
| Adnet, P | 11 |
| Haudecoeur, G | 13 |
| Teneur, F | 1 |
| Stix, I | 2 |
| Krivosic-Horber, RM | 13 |
| Fiege, M | 4 |
| Weisshorn, R | 3 |
| Ulrich Gerbershagen, M | 1 |
| Steinfath, M | 7 |
| Schulte Am Esch, J | 11 |
| Ording, H | 17 |
| Bendixen, D | 6 |
| Ranklev Twetman, E | 3 |
| Girard, T | 4 |
| Censier, K | 9 |
| Mueller, CR | 2 |
| Zorzato, F | 4 |
| Sei, Y | 1 |
| Hosoi, E | 1 |
| Gallagher, KL | 1 |
| Wyre, HW | 1 |
| Pudimat, PA | 1 |
| Holman, SJ | 1 |
| Venzon, DJ | 1 |
| Daly, JW | 1 |
| Holman, S | 1 |
| Uttenweiler, D | 1 |
| Both, M | 1 |
| Zink, W | 1 |
| Sinner, B | 1 |
| Martin, E | 1 |
| Graf, BM | 1 |
| Fink, RH | 1 |
| Loke, JC | 1 |
| Kraev, N | 1 |
| Sharma, P | 1 |
| Du, G | 1 |
| Patel, L | 2 |
| Kraev, A | 1 |
| MacLennan, DH | 7 |
| Baur, CP | 2 |
| Doetsch, S | 1 |
| Felleiter, P | 1 |
| Fricker, R | 2 |
| Heffron, JJ | 20 |
| Heytens, L | 3 |
| Nivoche, Y | 3 |
| Tegazzin, V | 3 |
| Tzanova, I | 1 |
| Glover, L | 1 |
| Ohlendieck, K | 2 |
| Wehner, M | 2 |
| Rueffert, H | 6 |
| Koenig, F | 2 |
| Olthoff, D | 8 |
| Deutrich, C | 4 |
| Schober, R | 1 |
| Froster, UG | 4 |
| Nelson, TE | 26 |
| Ginz, HF | 1 |
| Gillmeister, I | 1 |
| Schummer, C | 1 |
| Hommann, M | 1 |
| Schummer, W | 1 |
| Guis, S | 1 |
| Monnier, N | 2 |
| Kozak-Ribbens, G | 4 |
| Lunardi, J | 2 |
| Ghattas, B | 2 |
| Mattei, JP | 1 |
| Cozzone, PJ | 3 |
| Halsal, JP | 1 |
| Fukami, MC | 1 |
| Ganzberg, SI | 1 |
| Litman, RS | 1 |
| Cowan, G | 1 |
| Karaian, J | 1 |
| Mongan, P | 1 |
| Schöll, H | 1 |
| Müller, R | 1 |
| Xu, ZH | 2 |
| Ren, HZ | 1 |
| Zhang, X | 1 |
| Huang, YG | 2 |
| Ye, TH | 1 |
| Riehl, J | 1 |
| Esteve, E | 1 |
| Goth, S | 1 |
| Rydenfelt, K | 1 |
| Ranklev, E | 6 |
| Bodelsson, M | 1 |
| Gardill, A | 1 |
| Bross, T | 1 |
| Steinmann, D | 1 |
| Ortiz Gómez, JR | 1 |
| Jiang, D | 1 |
| Chen, W | 1 |
| Xiao, J | 1 |
| Wang, R | 1 |
| Kong, H | 1 |
| Jones, PP | 1 |
| Zhang, L | 1 |
| Chen, SR | 1 |
| Somers, CJ | 2 |
| McLoughlin, JV | 3 |
| Tollefson, G | 1 |
| Fletcher, JE | 27 |
| Hilf, M | 1 |
| Di Prospero, S | 1 |
| Bianchi, S | 1 |
| Di Lazzaro, M | 1 |
| Camilli-Giammei, T | 1 |
| Mitchell, G | 8 |
| Marjanen, LA | 2 |
| Denborough, MA | 19 |
| Shaw, DC | 1 |
| Flewellen, EH | 11 |
| Arnett, DW | 1 |
| Mori, K | 1 |
| Shingu, K | 1 |
| L'ahucký, R | 1 |
| Fischer, K | 1 |
| Augustini, C | 1 |
| Pazdera, J | 2 |
| Hradecký, J | 1 |
| Cvejn, J | 1 |
| Zich, V | 1 |
| Siler, R | 1 |
| Hruban, V | 1 |
| Cepica, S | 1 |
| van den Hende, C | 3 |
| Muylle, E | 3 |
| Vlaminck, K | 1 |
| Oyaert, W | 3 |
| Pohlann, R | 1 |
| Schemel, D | 1 |
| Lyhs, L | 1 |
| Fletcher, R | 5 |
| McGrath, CJ | 6 |
| Lee, JC | 6 |
| Rempel, WE | 13 |
| Iwatsuki, N | 2 |
| Koga, Y | 1 |
| Amaha, K | 2 |
| Schwartz, L | 1 |
| Rockoff, MA | 2 |
| Koka, BV | 1 |
| Vögeli, P | 2 |
| Stranzinger, G | 3 |
| Schneebeli, H | 1 |
| Hagger, C | 1 |
| Künzi, N | 1 |
| Gerwig, C | 1 |
| Kiel, JL | 1 |
| Erwin, DN | 1 |
| Eng, GD | 1 |
| Becker, MJ | 1 |
| Basrur, PK | 4 |
| Frombach, S | 1 |
| McDonell, WN | 4 |
| Seeler, DC | 2 |
| Gerrard, JM | 1 |
| Duncan, PG | 1 |
| Koshyk, SA | 1 |
| Glover, SM | 1 |
| McCrea, JM | 1 |
| Payne, JP | 1 |
| Hildebrand, SV | 2 |
| Howitt, GA | 1 |
| Bora, VM | 1 |
| Polazhinets, MN | 1 |
| Shelepets, TM | 1 |
| Marín Ruiz, R | 1 |
| Zepeda, J | 1 |
| Gronert, GA | 23 |
| Alarcón Zurita, A | 1 |
| Pizá Buñola, C | 1 |
| Morey Molina, A | 1 |
| Marco Franco, JE | 1 |
| Bestard Palmer, J | 1 |
| Mas Dégano, J | 1 |
| Verburg, MP | 1 |
| Van Bennekom, CA | 1 |
| Oerlemans, FT | 1 |
| De Bruyn, CH | 1 |
| Solomons, CC | 1 |
| Masson, NC | 1 |
| Byrick, RJ | 1 |
| Rose, DK | 1 |
| Ranganathan, N | 1 |
| Newberg, LA | 1 |
| Lambert, EH | 1 |
| Reed, S | 1 |
| Giger, U | 1 |
| Kaplan, RF | 1 |
| Lorkin, PA | 1 |
| Lehmann, H | 1 |
| Gloyna, DF | 1 |
| Manley, SV | 1 |
| Kelly, AB | 1 |
| Hodgson, D | 1 |
| Ohnishi, ST | 6 |
| Taylor, S | 1 |
| Fernsebner, B | 1 |
| Thomas, J | 1 |
| Anderson, IL | 3 |
| Rawstron, RE | 1 |
| Dunlop, DJ | 1 |
| Sporn, P | 2 |
| Gallant, EM | 11 |
| Godt, RE | 1 |
| Hall, GM | 9 |
| Lucke, JN | 11 |
| Lister, D | 12 |
| Reynolds, RC | 1 |
| Taylor, SR | 3 |
| Brownell, AK | 3 |
| Szabo, M | 1 |
| Mortier, W | 4 |
| Biesel, C | 1 |
| Britt, BA | 22 |
| Frodis, W | 4 |
| Scott, E | 4 |
| Clements, MJ | 1 |
| Endrenyi, L | 6 |
| Jørgensen, PF | 3 |
| van Rensburg, AJ | 1 |
| Thompson, RL | 1 |
| Onofrio, BM | 1 |
| Blanck, TJ | 2 |
| Gruener, R | 2 |
| Suffecool, SL | 1 |
| Thompson, M | 1 |
| Milde, JH | 7 |
| Muteki, T | 1 |
| Tokutomi, Y | 1 |
| Ueda, N | 1 |
| Nakamura, Y | 1 |
| Matsuoka, H | 1 |
| Iwai, Y | 1 |
| Yoshitake, K | 1 |
| Tsuda, H | 1 |
| Barnes, PK | 1 |
| Addis, PB | 4 |
| Crimi, AJ | 2 |
| Dodd, MJ | 1 |
| Phattiyakul, P | 1 |
| Silpasuvan, S | 1 |
| Kukoyi, EA | 1 |
| Martin, FB | 1 |
| Lewandowski, KB | 1 |
| Chausmer, AB | 1 |
| Schanus, EG | 1 |
| Schendel, F | 1 |
| Lovrien, RE | 1 |
| McGrath, C | 1 |
| Sullivan, JS | 1 |
| Waldron-Mease, E | 1 |
| Klein, LV | 1 |
| Leitch, M | 1 |
| Dantzer, R | 3 |
| Hatey, F | 1 |
| Bee, DE | 1 |
| Green, RA | 1 |
| Morio, M | 1 |
| Rettig, B | 1 |
| Weitz, H | 1 |
| Plötz, J | 2 |
| Braun, J | 1 |
| Gericke, B | 1 |
| Okumura, F | 2 |
| Crocker, BD | 2 |
| Kozłowski, PB | 1 |
| Mambo, NC | 1 |
| Silver, MD | 1 |
| McLaughlin, PR | 1 |
| Huckell, VF | 1 |
| McEwan, PM | 1 |
| Morch, JE | 1 |
| Artru, AA | 1 |
| Fairhurst, AS | 1 |
| Hamamoto, V | 1 |
| Macri, J | 1 |
| Ahern, CP | 3 |
| Wilson, P | 2 |
| Inagaki, M | 1 |
| Koyama, A | 1 |
| Sakata, S | 1 |
| Tonogai, R | 1 |
| Yamada, Y | 1 |
| Kawai, H | 1 |
| Iwasa, M | 1 |
| Kondo, A | 1 |
| Miyoshi, K | 1 |
| Jessen, CR | 1 |
| Ruff, J | 1 |
| Tonner, PH | 2 |
| Scholz, J | 10 |
| Richter, A | 6 |
| Löscher, W | 6 |
| Wlaz, P | 1 |
| Hadji, B | 1 |
| Otsu, K | 2 |
| Nishida, K | 1 |
| Kimura, Y | 1 |
| Kuzuya, T | 1 |
| Hori, M | 1 |
| Kamada, T | 1 |
| Tada, M | 1 |
| Tripolitis, L | 4 |
| Hubert, M | 1 |
| Vita, GM | 1 |
| Levitt, RC | 2 |
| Dziadzka, A | 1 |
| Greim, CA | 1 |
| Kraas, E | 1 |
| Singh, S | 2 |
| Becker, K | 1 |
| Lenzen, C | 2 |
| Köchling, A | 4 |
| Foster, PS | 8 |
| Beech, J | 4 |
| Greim, C | 1 |
| Rumberger, E | 1 |
| Sato, N | 1 |
| Brum, JM | 1 |
| Mitsumoto, H | 1 |
| DeBoer, GE | 1 |
| Bello, N | 1 |
| Saulnier, F | 2 |
| Lestavel, P | 2 |
| Adnet-Bonte, C | 1 |
| Reyford, H | 6 |
| Etchrivi, T | 1 |
| Tavernier, B | 3 |
| Krivosic-Horber, R | 12 |
| Deufel, T | 2 |
| Sudbrak, R | 1 |
| Feist, Y | 1 |
| Rübsam, B | 1 |
| Du Chesne, I | 1 |
| Schäfer, KL | 1 |
| Grimm, T | 1 |
| Hartung, EJ | 1 |
| Carr, AS | 2 |
| Lerman, J | 2 |
| Cunliffe, M | 1 |
| McLeod, ME | 1 |
| Gerdes, C | 3 |
| Petersen, WC | 1 |
| Crouch, ER | 1 |
| Ducart, A | 1 |
| Renaud, B | 1 |
| Riou, B | 1 |
| Dickinson, PJ | 1 |
| Sullivan, M | 1 |
| Geers, R | 4 |
| Bleus, E | 1 |
| Van Schie, T | 1 |
| Villé, H | 4 |
| Gerard, H | 1 |
| Janssens, S | 3 |
| Nackaerts, G | 1 |
| Decuypere, E | 1 |
| Jourquin, J | 1 |
| Bolt, R | 1 |
| Fries, R | 2 |
| Klont, RE | 1 |
| Lambooy, E | 1 |
| van Logtestijn, JG | 1 |
| O'Flynn, RP | 1 |
| Shutack, JG | 1 |
| Kaufmann, MA | 2 |
| Drewe, J | 4 |
| Lazzell, VA | 1 |
| Burrows, FA | 1 |
| Creighton, RE | 1 |
| Adnet, PJ | 13 |
| Krivosic, I | 4 |
| Reyford, HG | 4 |
| Adamantidis, MM | 8 |
| Medahoui, H | 1 |
| Gürtler, H | 1 |
| Neubert, E | 1 |
| Wedel, DJ | 6 |
| Johnsen, RD | 1 |
| Louis, CF | 7 |
| Roghair, T | 2 |
| Mickelson, JR | 7 |
| Bichel, T | 1 |
| Canivet, JL | 1 |
| Damas, P | 1 |
| Lamy, M | 1 |
| Burns, AP | 1 |
| Hall, G | 1 |
| Pusey, CD | 1 |
| Hopkins, D | 1 |
| Shipton, EA | 1 |
| Gareau, PJ | 1 |
| Janzen, EG | 1 |
| Towner, RA | 1 |
| Stewart, WA | 1 |
| Decanniere, C | 3 |
| Van Hecke, P | 3 |
| Vanstapel, F | 2 |
| Breucking, E | 1 |
| Kochs, E | 2 |
| Hoffman, WE | 2 |
| Kaus, SJ | 1 |
| Rumberger, R | 1 |
| Isaacs, H | 7 |
| Badenhorst, M | 3 |
| Lu, M | 1 |
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| Kennedy, CF | 1 |
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| Schmitt, J | 1 |
| Schmidt, K | 1 |
| Ritter, H | 1 |
| Garstka, J | 1 |
| Wierusz, L | 1 |
| de Jong, RH | 1 |
| Heavner, JE | 1 |
| Amory, DW | 1 |
| Kacinec, J | 1 |
| Malatinský, J | 1 |
| Sadlon, P | 1 |
| Klimasová, A | 1 |
| Purschke, R | 1 |
| Zindler, M | 1 |
| Baraka, A | 1 |
| Rebeiz, J | 1 |
| Moghrabi, R | 1 |
| Morgan, JG | 1 |
| Popinigis, J | 1 |
| Brucker, RF | 1 |
| Taylor, CA | 1 |
| Dilworth, NM | 1 |
| Beasley, H | 1 |
| Iuchi, Y | 1 |
| Madono, K | 1 |
| Yamamoto, T | 1 |
| Yoshizumi, M | 1 |
| Ono, T | 1 |
| Keaney, NP | 2 |
| Wedley, JR | 1 |
| Jaffe, EC | 1 |
| Kerr, WS | 1 |
| King, JO | 1 |
| Verburg, C | 1 |
| Takahashi, T | 1 |
| Takasaki, M | 1 |
| Dohi, S | 1 |
| Rizk, SF | 1 |
| Bradley, WG | 1 |
| Bull, AB | 1 |
| Gordon, A | 1 |
| Humphrey, JG | 1 |
| Rewcastle, NB | 1 |
| Althoff, H | 1 |
| Short, CE | 1 |
| Paddleford, RR | 1 |
| Nesvetov, AM | 1 |
| Dovgiĭ, GM | 1 |
| L'vova, TN | 1 |
| Sumner, DW | 2 |
| Sybesma, W | 1 |
| Henrickson, RL | 1 |
| Falk, SN | 1 |
| Brown, LL | 1 |
| Stoyka, WW | 1 |
| Garvey, MB | 1 |
| Pöntinen, PJ | 1 |
| Abele, K | 1 |
| Autere, T | 1 |
| Kyei-Mensah, K | 1 |
| Tyrrell, JH | 1 |
| Hargreaves, JB | 1 |
| Parikh, RK | 1 |
| Mulrooney, PL | 1 |
| Harpman, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Freeman-Sheldon Syndrome Evaluation and Diagnosis in Clinical Settings (FSS-EDICT) I: a Case-Control, Cross-Sectional Study of Baseline and Stress Physiology Parameters[NCT01306994] | 0 participants (Actual) | Observational | 2014-03-31 | Withdrawn (stopped due to Lack of patient interest) | |||
| Implication of Patient in the Making Ready of Recommendations for the Antivitamin K's Gestion in Case of Thrombosis Embolic Venous's Illness. Randomised Study for Clinical Validation.[NCT00227097] | 300 participants | Observational | 2002-12-31 | Terminated | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
39 reviews available for halothane and Anesthesia Related Hyperthermia
| Article | Year |
|---|---|
Unexpected MH deaths without exposure to inhalation anesthetics in pediatric patients.
Topics: Anesthesia, General; Anesthetics, Inhalation; Child; Child, Preschool; Genotype; Halothane; Humans; | 2013 |
DNA testing for malignant hyperthermia: the reality and the dream.
Topics: Biopsy; Caffeine; Calcium Channels; Calcium Channels, L-Type; Computational Biology; Genetic Predisp | 2014 |
Clinical protocol for the management of malignant hyperthermia.
Topics: Adolescent; Adult; Caffeine; Calcium Signaling; Child; Child, Preschool; Clinical Protocols; Critica | 2017 |
Escobar syndrome: is this child prone to malignant hyperthermia?
Topics: Abnormalities, Multiple; Anesthetics, Inhalation; Halothane; Humans; Infant; Male; Malignant Hyperth | 2009 |
Defective Mg2+ regulation of RyR1 as a causal factor in malignant hyperthermia.
Topics: Caffeine; Calcium; Cytosol; Halothane; Humans; Magnesium; Malignant Hyperthermia; Muscle, Skeletal; | 2007 |
[Anesthesia in malignant hyperthermia].
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Calcium Signaling; Child; Child, Prescho | 2008 |
Current concepts. The malignant hyperthermia syndrome.
Topics: Animals; Dantrolene; Disease Models, Animal; Halothane; Humans; Malignant Hyperthermia; Muscles; Swi | 1983 |
[Malignant hyperthermia, syndrome malin, and heat stroke].
Topics: Adolescent; Adult; Anesthesia, Inhalation; Animals; Calcium; Creatine Kinase; Halothane; Heat Exhaus | 1983 |
[Possibilities and risks of determining susceptibility to malignant hyperthermia].
Topics: Animals; Halothane; Malignant Hyperthermia; Swine; Swine Diseases | 1983 |
Porcine stress syndromes.
Topics: Animals; Disease Models, Animal; Drug Resistance; General Adaptation Syndrome; Glycolysis; Halothane | 1982 |
Malignant hyperthermia--pearls out of swine?
Topics: Animals; Body Temperature; Dantrolene; Disease Models, Animal; Halothane; Magnesium Sulfate; Maligna | 1980 |
General anesthetic agents (what every surgeon should know about anesthesia, but has been afraid to ask).
Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthetics; Cyclopropanes; Enflurane; Ether; Halothane | 1981 |
Malignant hyperthermia.
Topics: Adolescent; Adult; Anesthesia; Biopsy; Caffeine; Child; Child, Preschool; Clinical Protocols; Counse | 1994 |
Malignant hyperthermia.
Topics: Anesthesia; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Dantrolene; Haloth | 1998 |
[Sevoflurane in pediatric anesthesia. Malignant hyperthermia].
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Halothane; Humans; Malignant Hyperthermia; M | 1998 |
[Neurotoxicity of inhalation anesthetics, halothane].
Topics: Anesthetics, Inhalation; Animals; Central Nervous System; Chemical and Drug Induced Liver Injury; Ha | 1999 |
A review of the role of swine skeletal muscle in malignant hyperthermia.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Anura; Calcium; Dogs; Glycolysis; Haloth | 1975 |
Anesthetics and mitochondrial respiration.
Topics: Adenosine Diphosphate; Anesthetics; Anesthetics, Local; Animals; Barbiturates; Brain; Dose-Response | 1975 |
Treatment of porcine malignant hyperthermia. A review based on experimental studies.
Topics: Animals; Blood Glucose; Body Temperature; Carbon Dioxide; Catecholamines; Chlorpromazine; Dantrolene | 1975 |
Anaesthesia of pigs sensitive to malignant hyperthermia.
Topics: Anesthesia; Animals; Barbiturates; Body Temperature; Cardiac Output; Dantrolene; Halothane; Heart Ra | 1977 |
Epidemiology and inheritance of malignant hyperthermia.
Topics: Adenosine Triphosphate; Caffeine; Creatine Kinase; Female; Genetic Predisposition to Disease; Haloth | 1979 |
Preanesthetic diagnosis of malignant hyperthermia.
Topics: Adenosine Triphosphate; Caffeine; Cardiac Catheterization; Creatine Kinase; Halothane; Heart; Humans | 1979 |
Malignant hyperthermia.
Topics: Anesthesia, Inhalation; Animals; Calcium; Halothane; Humans; Malignant Hyperthermia; Muscle Contract | 1979 |
Heat stroke: a review.
Topics: Acclimatization; Adult; Age Factors; Animals; Body Temperature; Body Temperature Regulation; Brain; | 1976 |
[Malignant hyperthermia during an operation (a review of the literature)].
Topics: Acute Disease; Adolescent; Adult; Anesthesia; Anesthesia, General; Anesthesia, Inhalation; Animals; | 1976 |
Halothane-cooling contractures and regulation of the myoplasmic Ca2+ concentration in skeletal muscle.
Topics: Animals; Calcium; Cytoplasm; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Muscles | 1991 |
Malignant hyperthermia: relation to other diseases.
Topics: Caffeine; Calcium Channels; Diagnosis, Differential; Halothane; Humans; Malignant Hyperthermia; Musc | 1990 |
Current views of the molecular basis of the malignant hyperthermia syndrome.
Topics: Calcium; Calcium Channels; Halothane; Humans; Malignant Hyperthermia; Mitochondria, Muscle; Sarcolem | 1990 |
The halothane sensitivity locus and its linkage relationships.
Topics: Alleles; Alpha-Globulins; Animals; Blood Group Antigens; Genetic Linkage; Glucose-6-Phosphate Isomer | 1985 |
[Clinical features of malignant hyperthermia crisis].
Topics: Adolescent; Adult; Anesthesia, General; Arrhythmias, Cardiac; Carbon Dioxide; Child; Child, Preschoo | 1989 |
[Screening tests for malignant hyperthermia susceptibility].
Topics: Animals; Caffeine; Calcium; Cholinesterases; Contracture; Creatine Kinase; Cyclic AMP; Disease Susce | 1989 |
Standardization of the caffeine halothane muscle contracture test. North American Malignant Hyperthermia Group.
Topics: Biopsy; Caffeine; Clinical Laboratory Techniques; Disease Susceptibility; Halothane; Humans; Maligna | 1989 |
Pathophysiology of malignant hyperthermia.
Topics: Animals; Calcium; Creatine Kinase; Dantrolene; Disease Susceptibility; Halothane; Humans; Lymphocyte | 1989 |
[The influence of breeding precautions on the meat quality in swine].
Topics: Animals; Breeding; Female; Genotype; Halothane; Male; Malignant Hyperthermia; Meat; Swine; Swine Dis | 1988 |
Diagnosis of susceptibility to malignant hyperthermia in man.
Topics: Caffeine; Chemistry, Clinical; Disease Susceptibility; Halothane; Hematologic Tests; Humans; In Vitr | 1988 |
Effect of anesthetics on mitochondrial function.
Topics: Anesthesia, Inhalation; Anesthetics; Animals; Barbiturates; Dogs; Electron Transport; Guinea Pigs; H | 1973 |
[Malignant hyperthermia].
Topics: Age Factors; Alanine Transaminase; Anesthesia; Aspartate Aminotransferases; Carbon Dioxide; Halothan | 1972 |
Anaesthesia in the pig.
Topics: Analgesics; Anesthesia; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthesia, Intravenous; Anest | 1973 |
The importance of changes in body temperature in paediatric surgery and anaesthesia.
Topics: Anesthesia; Blood Transfusion; Body Temperature; Body Temperature Regulation; Child; Exchange Transf | 1973 |
7 trials available for halothane and Anesthesia Related Hyperthermia
| Article | Year |
|---|---|
Multicentre evaluation of in vitro contracture testing with bolus administration of 4-chloro-m-cresol for diagnosis of malignant hyperthermia susceptibility.
Topics: Biopsy; Caffeine; Cresols; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant | 2003 |
Genotype-phenotype comparison of the Swiss malignant hyperthermia population.
Topics: Caffeine; DNA Mutational Analysis; Gene Frequency; Genetic Heterogeneity; Genetic Predisposition to | 2001 |
Predictive tests for malignant hyperpyrexia.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Clinical Enzyme Tests; Clinical Trials as Topic; | 1975 |
Prediction of malignant hyperthermia susceptibility in low-risk subjects. An epidemiologic investigation of caffeine halothane contracture responses. The North American Malignant Hyperthermia Registry.
Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Child; Contracture; Disease Susceptibility; Female; Halot | 1992 |
A blinded comparison of noninvasive, in vivo phosphorus nuclear magnetic resonance spectroscopy and the in vitro halothane/caffeine contracture test in the evaluation of malignant hyperthermia susceptibility.
Topics: Adolescent; Adult; Caffeine; Child; Child, Preschool; Disease Susceptibility; Female; Halothane; Hum | 1991 |
Cytosolic free calcium concentrations in lymphocytes from malignant hyperthermia susceptible patients.
Topics: Adult; Aged; Benzofurans; Calcium; Child; Cytosol; Disease Susceptibility; Female; Fura-2; Halothane | 1990 |
Identification of susceptibility to malignant hyperpyrexia.
Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Creatine Kinase; Drug Hypersensitivity; Electrocardiograp | 1974 |
656 other studies available for halothane and Anesthesia Related Hyperthermia
| Article | Year |
|---|---|
Serendipity: Being in the Right Place at the Right Time.
Topics: Anesthetics, Inhalation; Halothane; Hemodynamics; Humans; Isoflurane; Malignant Hyperthermia; Nitrou | 2022 |
Malignant Hyperthermia: A Killer If Ignored.
Topics: Adolescent; Caffeine; China; Halothane; Humans; Malignant Hyperthermia; Mutation | 2022 |
Management of patients susceptible to malignant hyperthermia: A surgeon's perspective.
Topics: Caffeine; Child; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Retrospective St | 2022 |
Oral Dantrolene for Myopathic Symptoms in Malignant Hyperthermia-Susceptible Patients: A 25-Year Retrospective Cohort Study of Adverse Effects and Tolerability.
Topics: Dantrolene; Drug-Related Side Effects and Adverse Reactions; Fatigue; Halothane; Humans; Malignant H | 2023 |
A Case Report of an Incidental Ultrasound Finding in a Suspected Malignant Hyperthermia Patient.
Topics: Anesthetics, Inhalation; Dantrolene; Female; Halothane; Humans; Malignant Hyperthermia; Middle Aged; | 2022 |
Distinct pathophysiological characteristics in developing muscle from patients susceptible to malignant hyperthermia.
Topics: Caffeine; Calcium; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Muscle Contrac | 2023 |
What is malignant hyperthermia susceptibility?
Topics: Anesthesia; Biopsy; Caffeine; Halothane; Humans; Malignant Hyperthermia | 2023 |
Putative malignant hyperthermia mutation Ca
Topics: Animals; Calcium; Halothane; Heat-Shock Response; Large-Conductance Calcium-Activated Potassium Chan | 2023 |
Altered [Ca2+] Regulation in Cortical Neurons of Mice Susceptible to Malignant Hyperthermia: An In Vivo Study.
Topics: Animals; Calcium; Halothane; Malignant Hyperthermia; Mice | 2023 |
A multi-dimensional analysis of genotype-phenotype discordance in malignant hyperthermia susceptibility.
Topics: Adult; Anesthetics, Inhalation; Caffeine; Female; Genotype; Halothane; Humans; Malignant Hyperthermi | 2020 |
Untargeted metabolomics profiling of skeletal muscle samples from malignant hyperthermia susceptible patients.
Topics: Halothane; Humans; Hyperthermia; Malignant Hyperthermia; Metabolomics; Muscle, Skeletal | 2021 |
A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke.
Topics: Animals; Calcium; Calcium Channel Blockers; Halothane; Isoflurane; Malignant Hyperthermia; Mice; Mus | 2021 |
Dantrolene requires Mg
Topics: Adult; Animals; Calcium Signaling; Dantrolene; Female; Halothane; Humans; Magnesium; Male; Malignant | 2017 |
Skeletal Muscle Metabolic Dysfunction in Patients With Malignant Hyperthermia Susceptibility.
Topics: Adult; Anesthetics; Anthropometry; Caffeine; Case-Control Studies; Disease Susceptibility; Exercise | 2017 |
A genetic mystery in malignant hyperthermia 'solved'?
Topics: Anesthetics, Inhalation; Genetic Predisposition to Disease; Genetic Testing; Halothane; Humans; Male | 2018 |
Microdialysis and ultrasound elastography for monitoring of localized muscular reaction after pharmacological stimulation in rats.
Topics: Animals; Caffeine; Elasticity Imaging Techniques; Halothane; Malignant Hyperthermia; Microdialysis; | 2018 |
Ultrasound Elastography for Rapid, Real-time Detection of Localized Muscular Reaction in Malignant Hyperthermia-susceptible Pigs.
Topics: Anesthetics, Inhalation; Animals; Caffeine; Central Nervous System Stimulants; Disease Models, Anima | 2018 |
Malignant hyperthermia, environmental heat stress, and intracellular calcium dysregulation in a mouse model expressing the p.G2435R variant of RYR1.
Topics: Anesthetics, Inhalation; Animals; Caffeine; Calcium; Calcium Signaling; Dose-Response Relationship, | 2018 |
Has malignant hyperthermia really disappeared with halothane? Comment on Br J Anaesth 2017; 119: i44-52.
Topics: Anesthetics; Desflurane; Halothane; Humans; Malignant Hyperthermia; Thiopental | 2018 |
Abnormal calcium signalling and the caffeine-halothane contracture test.
Topics: Adult; Anesthetics, Inhalation; Caffeine; Calcium; Cells, Cultured; Disease Susceptibility; Dose-Res | 2019 |
Understanding malignant hyperthermia: each move forward opens our eyes to the distance left to travel.
Topics: Caffeine; Calcium; Contracture; Halothane; Humans; Malignant Hyperthermia | 2019 |
Masseter muscle rigidity and the role of DNA analysis to confirm malignant hyperthermia susceptibility.
Topics: Anesthetics, Inhalation; DNA; Halothane; Humans; Malignant Hyperthermia; Masseter Muscle; Muscle, Sk | 2019 |
Permeabilised skeletal muscle reveals mitochondrial deficiency in malignant hyperthermia-susceptible individuals.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Biopsy; Child; Electron Transport; Female; Genetic | 2019 |
Ryanodine receptor type 1 gene variants in the malignant hyperthermia-susceptible population of the United States.
Topics: Anesthetics, Inhalation; Calcium Channels; Calcium Channels, L-Type; DNA; Exons; Genetic Variation; | 2013 |
In vitro muscle contracture investigations on the malignant hyperthermia like episodes in myotonia congenita.
Topics: Anesthetics, Inhalation; Animals; Caffeine; Calcium; Central Nervous System Stimulants; Dose-Respons | 2013 |
Malignant hyperthermia in Canada: characteristics of index anesthetics in 129 malignant hyperthermia susceptible probands.
Topics: Adolescent; Adult; Aged; Anesthetics; Caffeine; Canada; Child; Child, Preschool; Dantrolene; Female; | 2014 |
Analysis of histomorphology in malignant hyperthermia-susceptible patients.
Topics: Adult; Caffeine; Female; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Halothane; | 2013 |
Sevoflurane is less sensitive than halothane for in vitro detection of malignant hyperthermia susceptibility.
Topics: Anesthetics, Inhalation; Biopsy; Disease Susceptibility; Dose-Response Relationship, Drug; Genetic P | 2013 |
Anesthetic drugs and onset of malignant hyperthermia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics; Anesthetics, Inhalation; Child; Child, Pres | 2014 |
The effect of succinylcholine on malignant hyperthermia events in susceptible swine.
Topics: Animals; Blood Gas Analysis; Blood Gas Monitoring, Transcutaneous; Halothane; Hemodynamics; Malignan | 2014 |
Ca2+ influx via the Na+/Ca2+ exchanger is enhanced in malignant hyperthermia skeletal muscle.
Topics: Animals; Calcium; Extracellular Space; Gene Knockdown Techniques; Halothane; Intracellular Space; Ma | 2014 |
Contractile elements in muscular fascial tissue - implications for in-vitro contracture testing for malignant hyperthermia.
Topics: Anesthesia, General; Anesthetics, General; Animals; Biopsy; Caffeine; Central Nervous System Stimula | 2014 |
Is lymphocyte adenosine a diagnostic marker of clinical malignant hyperthermia? A pilot study.
Topics: Adenosine; Anesthetics, Inhalation; Biomarkers; Calcium; Cresols; Female; Halothane; Humans; Lymphoc | 2015 |
Malignant hyperthermia testing in probands without adverse anesthetic reaction.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Dantrolene; Drug-Related Side Effects an | 2015 |
Is there a link between exertional heat stroke and susceptibility to malignant hyperthermia?
Topics: Adult; Anesthetics, Inhalation; Caffeine; Contracture; Disease Susceptibility; Female; Halothane; He | 2015 |
Cystathionine β-synthase-derived hydrogen sulfide is involved in human malignant hyperthermia.
Topics: Biopsy; Caffeine; Case-Control Studies; Cystathionine beta-Synthase; Dose-Response Relationship, Dru | 2016 |
Functional characterization of the RYR1 mutation p.Arg4737Trp associated with susceptibility to malignant hyperthermia.
Topics: Anesthetics; Arginine; B-Lymphocytes; Caffeine; Cell Line, Transformed; Cresols; Family Health; Fema | 2016 |
[In-vivo diagnosis of malignant hyperthermia susceptibility: a microdialysis study].
Topics: Adolescent; Adult; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Creatine; D | 2008 |
An in-vivo metabolic test for detecting malignant hyperthermia susceptibility in humans: a pilot study.
Topics: Adult; Biopsy; Caffeine; Case-Control Studies; Disease Susceptibility; Female; Halothane; Humans; La | 2008 |
Novel ryanodine receptor mutation that may cause malignant hyperthermia.
Topics: Amino Acid Substitution; Anesthetics, Inhalation; Austria; Caffeine; Calcium; Cells, Cultured; Centr | 2008 |
You're "hot" from pumping iron?
Topics: Anesthesia; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Creatine; Dietary | 2009 |
Anesthetic- and heat-induced sudden death in calsequestrin-1-knockout mice.
Topics: Anesthetics; Animals; Caffeine; Calcium; Calcium-Binding Proteins; Calsequestrin; Central Nervous Sy | 2009 |
Genetic variation in RYR1 and malignant hyperthermia phenotypes.
Topics: Anesthetics, Inhalation; Caffeine; Creatine Kinase; DNA Mutational Analysis; DNA, Complementary; Fem | 2009 |
Malignant hyperthermia susceptibility in a patient with mitochondrial disorder.
Topics: Abnormalities, Multiple; Aged; Anesthesia; Anesthetics, Inhalation; Caffeine; Halothane; Humans; Mal | 2009 |
Malignant hyperthermia-like syndrome and carnitine palmitoyltransferase II deficiency with heterozygous R503C mutation.
Topics: Amino Acid Substitution; Anesthetics, Inhalation; Arginine; Carnitine O-Palmitoyltransferase; Child, | 2009 |
Intramuscular injection of malignant hyperthermia trigger agents induces hypermetabolism in susceptible and nonsusceptible individuals.
Topics: Adolescent; Adult; Aged; Caffeine; Carbon Dioxide; Female; Halothane; Humans; Injections, Intramuscu | 2010 |
The role of CACNA1S in predisposition to malignant hyperthermia.
Topics: Adolescent; Adult; Aged; Amino Acid Sequence; Caffeine; Calcium Channels; Calcium Channels, L-Type; | 2009 |
Multigenerational Brazilian family with malignant hyperthermia and a novel mutation in the RYR1 gene.
Topics: Brazil; Caffeine; Contracture; Family; Female; Genetic Testing; Halothane; Humans; Male; Malignant H | 2009 |
Impaired interaction between skeletal ryanodine receptors in malignant hyperthermia.
Topics: Animals; Calcium; Computer Simulation; Disease Models, Animal; Halothane; Malignant Hyperthermia; Mu | 2009 |
Use of the caffeine-halothane contracture test for the diagnosis of malignant hyperthermia in Brazil.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Biopsy; Caffeine; Child; Child, Preschool; Contrac | 2010 |
Clinical features and diagnosis for Chinese cases with malignant hyperthermia: a case cluster from 2005 to 2007.
Topics: Adolescent; Adult; Caffeine; Child; China; Female; Halothane; Humans; In Vitro Techniques; Male; Mal | 2010 |
Store-operated Ca2+ entry in malignant hyperthermia-susceptible human skeletal muscle.
Topics: Blotting, Western; Calcium; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Microsco | 2010 |
In-vitro contracture testing for susceptibility to malignant hyperthermia: can halothane be replaced?
Topics: Anesthetics, Inhalation; Biopsy; Case-Control Studies; Desflurane; Dose-Response Relationship, Drug; | 2011 |
Malignant hyperthermia: presymptomatic screening and treatment 2011.
Topics: Anesthetics, Inhalation; Animals; Dantrolene; Halothane; Humans; Malignant Hyperthermia; Muscle Cont | 2011 |
Analysis of human cultured myotubes responses mediated by ryanodine receptor 1.
Topics: Adolescent; Adult; Aged; Caffeine; Calcium; Cells, Cultured; Child; Child, Preschool; Cresols; Dose- | 2011 |
Comparison of the therapeutic effectiveness of a dantrolene sodium solution and a novel nanocrystalline suspension of dantrolene sodium in malignant hyperthermia normal and susceptible pigs.
Topics: Animals; Biomarkers; Chemistry, Pharmaceutical; Dantrolene; Disease Models, Animal; Halothane; Hemod | 2011 |
Sevoflurane as a potential replacement for halothane in diagnostic testing for malignant hyperthermia susceptibility: results of a preliminary study.
Topics: Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Disease Susceptibility; Dose-R | 2011 |
Mice expressing T4826I-RYR1 are viable but exhibit sex- and genotype-dependent susceptibility to malignant hyperthermia and muscle damage.
Topics: Amino Acid Substitution; Anesthetics, Inhalation; Animals; Body Temperature; Female; Gene Expression | 2012 |
Novel double and single ryanodine receptor 1 variants in two Austrian malignant hyperthermia families.
Topics: Amino Acid Substitution; Anesthesia, General; Anesthetics, Inhalation; Caffeine; Calcium; Cells, Cul | 2012 |
3,5-Di-t-butyl catechol is a potent human ryanodine receptor 1 activator, not suitable for the diagnosis of malignant hyperthermia susceptibility.
Topics: Caffeine; Calcium; Calcium Channel Agonists; Catechols; Cells, Cultured; Dose-Response Relationship, | 2012 |
A family with discordance between malignant hyperthermia susceptibility and rippling muscle disease.
Topics: Anesthesia; Anesthesia, General; Anesthetics, Inhalation; Caffeine; Caveolin 3; Creatine Kinase; Fam | 2013 |
RYR1 mutations causing central core disease are associated with more severe malignant hyperthermia in vitro contracture test phenotypes.
Topics: Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Exons; Female; Halothane; Huma | 2002 |
Halothane-induced calcium release in cultured human skeletal muscle cells from a family susceptible to malignant hyperthermia with an unidentified mutation in chromosome 19.
Topics: Calcium; Cells, Cultured; Chromosomes, Human, Pair 19; Disease Susceptibility; Halothane; Humans; Ma | 2002 |
[Contraction-relaxation coupling of skeletal muscle in patients susceptible to malignant hyperthermia].
Topics: Anesthetics, Inhalation; Halothane; Humans; In Vitro Techniques; Isotonic Contraction; Malignant Hyp | 2002 |
Results of contracture tests with halothane, caffeine, and ryanodine depend on different malignant hyperthermia-associated ryanodine receptor gene mutations.
Topics: Adolescent; Adult; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Child; Chil | 2002 |
Reproducibility of in vitro contracture test results in patients tested for malignant hyperthermia susceptibility.
Topics: Adult; Anesthetics, Inhalation; Biopsy; Caffeine; Disease Susceptibility; Female; Halothane; Humans; | 2002 |
Phenotyping malignant hyperthermia susceptibility by measuring halothane-induced changes in myoplasmic calcium concentration in cultured human skeletal muscle cells.
Topics: Adolescent; Adult; Anesthetics, Inhalation; Calcium; Cell Culture Techniques; Child; Dose-Response R | 2002 |
"Noninvasive" testing for malignant hyperthermia susceptibility.
Topics: Caffeine; Calcium; Cresols; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Muscl | 2002 |
Patients with malignant hyperthermia demonstrate an altered calcium control mechanism in B lymphocytes.
Topics: Adolescent; Adult; B-Lymphocytes; Caffeine; Calcium; Child; Cresols; Disease Susceptibility; Halotha | 2002 |
Extending the skeletal muscle viability period in the malignant hyperthermia test.
Topics: Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Electric Stimulation; Halothan | 2003 |
[High resolution fluorescence microscopy in combination with mathematical modelling. First evidence of sub-cellular anesthetic effects on Ca2+ sparks in situ].
Topics: Anesthetics, Inhalation; Calcium; Calcium Signaling; Halothane; Humans; In Vitro Techniques; Maligna | 2003 |
Detection of a novel ryanodine receptor subtype 1 mutation (R328W) in a malignant hyperthermia family by sequencing of a leukocyte transcript.
Topics: Amino Acid Substitution; Anesthetics, Inhalation; Caffeine; Cell Line; DNA, Complementary; Halothane | 2003 |
Increased sensitivity of the ryanodine receptor to halothane-induced oligomerization in malignant hyperthermia-susceptible human skeletal muscle.
Topics: Anesthetics, Inhalation; Biopsy; Calcium; Calcium-Transporting ATPases; Cytoplasm; Halothane; Humans | 2004 |
Calcium release from sarcoplasmic reticulum is facilitated in human myotubes derived from carriers of the ryanodine receptor type 1 mutations Ile2182Phe and Gly2375Ala.
Topics: Adult; Aged; Caffeine; Calcium; Child; Child, Preschool; Cresols; Female; Genetic Predisposition to | 2003 |
A new mutation in the skeletal ryanodine receptor gene (RYR1) is potentially causative of malignant hyperthermia, central core disease, and severe skeletal malformation.
Topics: Adolescent; Base Sequence; Caffeine; DNA; DNA Mutational Analysis; Dysostoses; Family Health; Female | 2004 |
Genetic testing for malignant hyperthermia in North America.
Topics: Anesthetics, Inhalation; Caffeine; Genetic Testing; Halothane; Humans; Malignant Hyperthermia; Muscl | 2004 |
Similar susceptibility to halothane, caffeine and ryanodine in vitro reflects pharmacogenetic variability of malignant hyperthermia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Biopsy; Caffeine; Central Nervo | 2004 |
[Delayed onset of malignant hyperthermia crisis during a living donor liver transplantation caused by sevoflurane].
Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Gas Analysis; Caffeine; Central Nervou | 2004 |
Functional characterization of malignant hyperthermia-associated RyR1 mutations in exon 44, using the human myotube model.
Topics: Adolescent; Adult; Aged; Anesthetics; Biopsy; Caffeine; Calcium; Cells, Cultured; Central Nervous Sy | 2004 |
Comparative analysis of in vitro contracture tests with ryanodine and a combination of ryanodine with either halothane or caffeine: a comparative investigation in malignant hyperthermia.
Topics: Anesthetics, Inhalation; Caffeine; DNA; Halothane; Humans; In Vitro Techniques; Malignant Hypertherm | 2004 |
Mg2+ dependence of halothane-induced Ca2+ release from the sarcoplasmic reticulum in skeletal muscle from humans susceptible to malignant hyperthermia.
Topics: Anesthetics, Inhalation; Caffeine; Calcium; Central Nervous System Stimulants; Cytosol; Halothane; H | 2004 |
A case report of malignant hyperthermia in a dental clinic operating room.
Topics: Anesthetics, Inhalation; Child, Preschool; Dantrolene; Follow-Up Studies; Halothane; Humans; Jaw Fix | 2005 |
Malignant hyperthermia: update on susceptibility testing.
Topics: Algorithms; B-Lymphocytes; Biopsy; Caffeine; Disease Susceptibility; DNA Mutational Analysis; Haloth | 2005 |
Effects of caffeine, halothane, and 4-chloro-m-cresol on skeletal muscle lactate and pyruvate in malignant hyperthermia-susceptible and normal swine as assessed by microdialysis.
Topics: Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous; A | 2006 |
The dose-response relationship and regional distribution of lactate after intramuscular injection of halothane and caffeine in malignant hyperthermia-susceptible pigs.
Topics: Anesthetics, Inhalation; Animals; Caffeine; Carbon Dioxide; Disease Susceptibility; Dose-Response Re | 2006 |
Validity and new malignant hyperthermia diagnostic procedures.
Topics: Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Reproducibility of Results; | 2006 |
Mg2+ dependence of Ca2+ release from the sarcoplasmic reticulum induced by sevoflurane or halothane in skeletal muscle from humans susceptible to malignant hyperthermia.
Topics: Anesthetics, Inhalation; Calcium; Cytosol; Halothane; Humans; Magnesium; Malignant Hyperthermia; Met | 2006 |
Intraoperative hyperthermia in a child with neuroblastoma.
Topics: Anesthesia, General; Diagnosis, Differential; Fever; Halothane; Humans; Infant; Intraoperative Compl | 2006 |
Malignant hyperthermia in China.
Topics: Anesthesia, General; Caffeine; China; Halothane; Humans; In Vitro Techniques; Male; Malignant Hypert | 2006 |
Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse.
Topics: Anesthetics, Inhalation; Animals; Blood Gas Analysis; Body Temperature; Calcium; Cell Line; Cell Mem | 2006 |
Male preponderance of patients testing positive for malignant hyperthermia susceptibility.
Topics: Caffeine; Family; Female; Genetic Predisposition to Disease; Halothane; Humans; Male; Malignant Hype | 2007 |
Effects of ryanodine on skeletal muscle lactate and pyruvate in malignant hyperthermia-susceptible and normal swine as assessed by microdialysis.
Topics: Animals; Caffeine; Disease Susceptibility; Halothane; Kinetics; Lactates; Malignant Hyperthermia; Mi | 2008 |
A minimally invasive metabolic test with intramuscular injection of halothane 5 and 6 vol% to detect probands at risk for malignant hyperthermia.
Topics: Adult; Anesthetics, Inhalation; Blood Pressure; Carbon Dioxide; Creatine Kinase; Disease Susceptibil | 2007 |
Fulminant malignant hyperthermia.
Topics: Adult; Anesthetics, General; Caffeine; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contr | 2008 |
[Application of caffeine-halothane contracture test in the diagnosis of malignant hyperthermia].
Topics: Anesthetics, Inhalation; Caffeine; Creatine Kinase; Enzyme-Linked Immunosorbent Assay; Halothane; Hu | 2008 |
Reduced threshold for luminal Ca2+ activation of RyR1 underlies a causal mechanism of porcine malignant hyperthermia.
Topics: Anesthetics, Inhalation; Animals; Calcium; Cell Line; Cytosol; Dantrolene; Fever; Halothane; Humans; | 2008 |
Malignant hyperthermia in pigs: calcium ion uptake by mitochondria from skeletal muscle of susceptible animals given neuroleptic drugs and halothane.
Topics: Animals; Antipsychotic Agents; Calcium; Halothane; Malignant Hyperthermia; Mitochondria, Muscle; Swi | 1982 |
A case of neuroleptic malignant syndrome: in vitro muscle comparison with malignant hyperthermia.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Caffeine; Halothane; Humans; Male; Malignant Hyperthe | 1982 |
Effects of midazolam on directly stimulated muscle biopsies from control and malignant hyperthermia positive patients.
Topics: Anti-Anxiety Agents; Benzodiazepines; Caffeine; Halothane; Humans; In Vitro Techniques; Malignant Hy | 1984 |
[Malignant hyperthermia: biochemico-metabolic aspects and personal experiences].
Topics: Adult; Dantrolene; Female; Halothane; Humans; Male; Malignant Hyperthermia; Succinylcholine | 1984 |
Plasma cortisol levels in pigs susceptible and resistant to malignant hyperthermia.
Topics: Adrenocorticotropic Hormone; Animals; Growth; Halothane; Hydrocortisone; Malignant Hyperthermia; Str | 1981 |
Effect of halothane on adenylate kinase in porcine malignant hyperpyrexia.
Topics: Adenosine Monophosphate; Adenylate Kinase; Animals; Disease Models, Animal; Dose-Response Relationsh | 1982 |
Comparison of adenylate kinase from normal and malignant hyperpyrexic porcine muscle.
Topics: Adenylate Kinase; Amino Acids; Animals; Chemical Phenomena; Chemistry; Halothane; Malignant Hyperthe | 1983 |
Prolonged electromechanical coupling time intervals in skeletal muscle of pigs susceptible to malignant hyperthermia.
Topics: Animals; Caffeine; Disease Models, Animal; Electric Stimulation; Halothane; Kinetics; Malignant Hype | 1983 |
Dantrolene does not block calcium pulse-induced calcium release from a putative calcium channel in sarcoplasmic reticulum from malignant hyperthermia and normal pig muscle.
Topics: Animals; Caffeine; Calcium; Dantrolene; Halothane; Ion Channels; Malignant Hyperthermia; Muscle Cont | 1984 |
[Biochemical and biophysical indicators in muscle biopsies (m. longissimus dorsi) in relation to the halothane and creatine kinase test in pigs].
Topics: Animals; Creatine Kinase; Halothane; Malignant Hyperthermia; Meat; Muscles; Muscular Diseases; Swine | 1983 |
[Changes in reactivity to halothane after administration of mephenytoin].
Topics: Animals; Halothane; Hydantoins; Malignant Hyperthermia; Mephenytoin; Swine; Swine Diseases | 1983 |
[Halothane-induced malignant hyperthermia (MH) in the Belgian Landrace breed of pigs: some findings concerning the role of subcellular fractions (author's transl)].
Topics: Animals; Calcium-Transporting ATPases; Cyanides; Halothane; Magnesium; Malignant Hyperthermia; Muscl | 1980 |
[Malignant hyperthermia in halothane-sensitive swine following maximal neuromotor stress].
Topics: Animals; Halothane; Malignant Hyperthermia; Physical Exertion; Swine; Swine Diseases | 1984 |
Investigation of malignant hyperthermia in Denmark and Sweden.
Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Child; Creatine Kinase; Disease Susceptibility; Female; G | 1984 |
A protocol for the investigation of malignant hyperpyrexia (MH) susceptibility. The European Malignant Hyperpyrexia Group.
Topics: Biopsy; Caffeine; Disease Susceptibility; Genetic Testing; Halothane; Humans; In Vitro Techniques; M | 1984 |
Halothane testing for malignant hyperthermia in swine: dose-response effects.
Topics: Animals; Dose-Response Relationship, Drug; False Negative Reactions; Halothane; Malignant Hypertherm | 1984 |
[Contracture responses of the muscle from a patient with malignant hyperthermia to drugs].
Topics: Adolescent; Diltiazem; Enflurane; Halothane; Humans; In Vitro Techniques; Male; Malignant Hypertherm | 1984 |
Masseter spasm with anesthesia: incidence and implications.
Topics: Anesthetics; Child; Child, Preschool; Creatine Kinase; Halothane; Humans; Infant; Malignant Hyperthe | 1984 |
Relationships between the H and A-O blood types, phosphohexose isomerase and 6-phosphogluconate dehydrogenase red cell enzyme systems and halothane sensitivity, and economic traits in a superior and an inferior selection line of swiss landrace pigs.
Topics: Alleles; Animals; Blood Group Antigens; Erythrocytes; Female; Gene Frequency; Genotype; Glucose-6-Ph | 1984 |
Thermochemiluminescent assay of porcine, rat, and human erythrocytes for antioxidative deficiencies.
Topics: Animals; Dinitrochlorobenzene; Erythrocytes; Halothane; Horseradish Peroxidase; Hot Temperature; Hum | 1984 |
Electrodiagnostic tests in the detection of malignant hyperthermia.
Topics: Adolescent; Adult; Caffeine; Electric Stimulation; Electromyography; Evoked Potentials; Female; Halo | 1984 |
Platelet morphology and membrane bound calcium in porcine stress syndrome.
Topics: Animals; Blood Platelets; Calcium; Cell Membrane; Electron Probe Microanalysis; General Adaptation S | 1983 |
Halothane and halothane/succinylcholine induced malignant hyperthermia (porcine stress syndrome) in a population of Ontario boars.
Topics: Animals; Disease Susceptibility; Drug Combinations; Halothane; Male; Malignant Hyperthermia; Ontario | 1983 |
Halothane stimulates the aggregation of platelets of both normal individuals and those susceptible to malignant hyperthermia.
Topics: Adenosine Diphosphate; Adolescent; Adult; Blood Platelets; Blood Proteins; Disease Susceptibility; F | 1983 |
Anaesthetic deaths.
Topics: Anesthesia, General; Anesthetics; Chemical and Drug Induced Liver Injury; Halothane; History, 19th C | 1983 |
Succinylcholine infusion associated with hyperthermia in ponies anesthetized with halothane.
Topics: Acidosis; Anesthesia, Endotracheal; Animals; Halothane; Horse Diseases; Horses; Malignant Hypertherm | 1983 |
[Malignant hyperthermia during fluothane anesthesia].
Topics: Adult; Anesthesia, Inhalation; Halothane; Humans; Male; Malignant Hyperthermia | 1983 |
[Malignant hyperthermia. Report of a case].
Topics: Abortion, Incomplete; Adolescent; Adult; Anesthesia, General; Child; Creatine Kinase; Female; Haloth | 1983 |
Postoperative malignant hyperthermia.
Topics: Diagnostic Errors; Halothane; Humans; Malignant Hyperthermia | 1984 |
[Acute renal failure in a patient anesthetized with halothane].
Topics: Acute Kidney Injury; Adult; Anesthesia, Inhalation; Halothane; Humans; Male; Malignant Hyperthermia | 1984 |
Malignant hyperthermia: adenine incorporation and adenine metabolism in human platelets, influenced by halothane.
Topics: Adenine; Blood Platelets; Halothane; Humans; Kinetics; Malignant Hyperthermia; Reference Values | 1984 |
Platelet model for halothane-induced effects on nucleotide metabolism applied to malignant hyperthermia.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Blood Platelets; Chromatogra | 1984 |
Halothane-succinylcholine induced masseter spasm: indicative of malignant hyperthermia susceptibility?
Topics: Caffeine; Child; Child, Preschool; Creatine Kinase; Female; Halothane; Humans; Male; Malignant Hyper | 1984 |
Noneffectiveness of verapamil in preventing halothane-induced malignant hyperthermia in susceptible swine.
Topics: Anesthesia, Inhalation; Animals; Halothane; Malignant Hyperthermia; Swine; Swine Diseases; Verapamil | 1984 |
In vivo and in vitro responses to magnesium sulphate in porcine malignant hyperthermia.
Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Contracture; Halo | 1980 |
Management of a malignant hyperthermia patient during cardiopulmonary bypass.
Topics: Anesthesia; Carbon Dioxide; Cardiac Catheterization; Cardiopulmonary Bypass; Coronary Vessels; Elect | 1982 |
Failure to induce malignant hyperthermia in myotonic goats.
Topics: Animals; Disease Susceptibility; Goats; Halothane; Malignant Hyperthermia; Myotonia Congenita; Succi | 1983 |
In vitro contracture tests for susceptibility to malignant hyperthermia.
Topics: Caffeine; Disease Susceptibility; Drug Interactions; Halothane; Humans; Malignant Hyperthermia; Musc | 1983 |
Halothane-induced ATP depletion in platelets from patients susceptible to malignant hyperthermia and from controls.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adolescent; Adult; Blood Pla | 1983 |
Investigation of malignant hyperthermia: analysis of skeletal muscle proteins from normal and halothane sensitive pigs by two dimensional gel electrophoresis.
Topics: Actins; Animals; Electrophoresis, Polyacrylamide Gel; Fructose-Bisphosphate Aldolase; Glyceraldehyde | 1983 |
Spectrum of susceptibility to malignant hyperthermia--diagnostic dilemma.
Topics: Animals; Body Temperature; Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; | 1983 |
Is theophylline, aminophylline, or caffeine (methylxanthines) contraindicated in malignant hyperthermia susceptible patients?
Topics: Adolescent; Adult; Aminophylline; Caffeine; Child; Halothane; Humans; In Vitro Techniques; Male; Mal | 1983 |
Malignant hyperthermia-like reactions in three anesthetized horses.
Topics: Anesthesia, General; Animals; Dantrolene; Female; Halothane; Horse Diseases; Horses; Male; Malignant | 1983 |
The control of muscle contracture by the action of dantrolene on the sarcolemma.
Topics: Animals; Caffeine; Dantrolene; Diaphragm; Dinitrophenols; Dose-Response Relationship, Drug; Halothan | 1983 |
Calcium-induced Ca2+ release from sarcoplasmic reticulum of pigs susceptible to malignant hyperthermia. The effects of halothane and dantrolene.
Topics: Animals; Calcium; Dantrolene; Halothane; Kinetics; Malignant Hyperthermia; Sarcoplasmic Reticulum; S | 1983 |
A protocol for malignant hyperthermia.
Topics: Anesthesia, Conduction; Anesthesia, Inhalation; Halothane; Humans; Malignant Hyperthermia; Succinylc | 1980 |
Malignant hyperthermia: fighting a fatal fever.
Topics: Child, Preschool; Female; Halothane; Humans; Male; Malignant Hyperthermia | 1981 |
Screening for malignant hyperthermia susceptibility.
Topics: Caffeine; Dantrolene; Halothane; Humans; Malignant Hyperthermia; Mass Screening; Muscle Contraction; | 1980 |
[Malignant hyperthermia-results of familial investigations in Austria (author's transl)].
Topics: Adenosine Triphosphate; Austria; Caffeine; Calcium; Chlorpromazine; Creatine Kinase; Halothane; Huma | 1981 |
Mechanical properties of normal and malignant hyperthemia susceptible porcine muscle: effects of halothane and other drugs.
Topics: Animals; Anura; Caffeine; Drug Interactions; Epinephrine; Halothane; In Vitro Techniques; Male; Mali | 1980 |
Masseter spasm induced by succinylcholine in children: contracture testing for malignant hyperthermia: report of six cases.
Topics: Anesthesia; Caffeine; Child; Child, Preschool; Halothane; Humans; Male; Malignant Hyperthermia; Mass | 1982 |
Cellular membrane potentials and contractile threshold in mammalian skeletal muscle susceptible to malignant hyperthermia.
Topics: Animals; Dose-Response Relationship, Drug; Halothane; Malignant Hyperthermia; Membrane Potentials; M | 1982 |
The in-vitro caffeine contracture test: influence of the muscle histochemical profile on test results.
Topics: Animals; Caffeine; Halothane; Histocytochemistry; Male; Malignant Hyperthermia; Muscle Contraction; | 1982 |
Pharmacological in-vitro studies in malignant hyperthermia in childhood.
Topics: Adolescent; Biopsy; Caffeine; Child; Child, Preschool; Dose-Response Relationship, Drug; Halothane; | 1982 |
Comparison of the caffeine skinned fibre tension (CSFT) test with the caffeine-halothane contracture (CHC) test in the diagnosis of malignant hyperthermia.
Topics: Anesthesia; Caffeine; Calcium; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscl | 1982 |
Influence of nutrition on malignant hyperthermia in pigs.
Topics: Anesthesia, Inhalation; Animals; Halothane; Malignant Hyperthermia; Swine; Swine Diseases | 1982 |
A halothane-induced biochemical defect in muscle of normal and malignant hyperthermia-susceptible Landrace pigs.
Topics: Adenosine Triphosphate; Animals; Body Temperature; Glucosephosphates; Halothane; Hydrogen-Ion Concen | 1980 |
Human malignant hyperthermia: awake episodes and correction by dantrolene.
Topics: Adenosine Triphosphate; Adult; Caffeine; Dantrolene; Fatigue; Female; Halothane; Humans; In Vitro Te | 1980 |
Malignant hyperthermia.
Topics: Animals; Halothane; Malignant Hyperthermia; Swine | 1980 |
Calcium uptake by isolated sarcoplasmic reticulum: examination of halothane inhibition, pH dependence, and Ca2+ dependence of normal and malignant hyperthermic human muscle.
Topics: Calcium; Halothane; Humans; Hydrogen-Ion Concentration; Malignant Hyperthermia; Muscles; Sarcoplasmi | 1981 |
Variations in onset of porcine malignant hyperthermia.
Topics: Anesthetics; Animals; Dose-Response Relationship, Drug; Ethers; Halothane; Hydrocarbons, Fluorinated | 1981 |
[A case report of malignant hyperthermia (author's transl)].
Topics: Anesthesia, Intravenous; Child, Preschool; Halothane; Humans; Male; Malignant Hyperthermia; Succinyl | 1980 |
Recent advances in anaesthesia.
Topics: Alfaxalone Alfadolone Mixture; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesiology; Bupren | 1980 |
Influence of pH, temperature, halothane and its metabolites on osmotic fragility of erythrocytes of malignant hyperthermia-susceptible and resistant pigs.
Topics: Animals; Erythrocytes; Halothane; Hemolysis; Hydrogen-Ion Concentration; In Vitro Techniques; Malign | 1981 |
Acepromazine and droperidol inhibition of halothane-induced malignant hyperthermia (porcine stress syndrome) in swine.
Topics: Acepromazine; Animals; Droperidol; Halothane; Malignant Hyperthermia; Stress, Physiological; Swine; | 1981 |
Suspected malignant hyperthermia in a strabismus patient. A case report.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Child; Child, Preschool; Creatine Kinase; Esotropia; F | 1981 |
Porcine stress syndrome and postmortem muscle characteristics of two purebreds and three specific terminal crosses.
Topics: Animals; Crosses, Genetic; Female; Halothane; Malignant Hyperthermia; Muscle Rigidity; Muscles; Swin | 1981 |
Rhabdomyolysis, myoglobinuria and hyperpyrexia caused by suxamethonium in a child with increased serum creatine kinase concentrations.
Topics: Anesthesia, Inhalation; Child, Preschool; Creatine Kinase; Female; Halothane; Humans; Male; Malignan | 1981 |
Calcium content and contracture in isolated muscle of malignant hyperthermia in pigs.
Topics: Animals; Caffeine; Calcium; Halothane; In Vitro Techniques; Magnesium; Malignant Hyperthermia; Muscl | 1981 |
Malignant hyperthermia (MH): porcine erythrocyte damage from oxidation and glutathione peroxidase deficiency.
Topics: Animals; Catalase; Erythrocytes; Glutathione Peroxidase; Glutathione Reductase; Halothane; Malignant | 1981 |
Temperature dependence of muscle function in malignant hyperpyrexia-susceptible swine.
Topics: Animals; Caffeine; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Potas | 1981 |
Malignant hyperthermia in a halothane-anesthetized horse.
Topics: Anesthesia, Inhalation; Animals; Dantrolene; Fluid Therapy; Halothane; Horse Diseases; Horses; Male; | 1981 |
Plasma dopamine-beta-hydroxylase and platelet monoamine oxidase activities in pigs with different susceptibility to the malignant hyperthermia syndrome by halothane.
Topics: Animals; Blood Platelets; Disease Susceptibility; Dopamine beta-Hydroxylase; Female; Halothane; Male | 1981 |
Effect of temperature, time and fascicle size on the caffeine contracture test.
Topics: Caffeine; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Techniques; Malignant Hypert | 1980 |
Porcine malignant hyperthermia--failure of dantrolene dose response to diagnose susceptibility (halothane effect).
Topics: Animals; Dantrolene; Dose-Response Relationship, Drug; Drug Synergism; Female; Halothane; Male; Mali | 1980 |
Effects of temperature, adenosine triphosphate and magnesium concentrations on the contraction of actomyosin isolated from halothane-sensitive and -insensitive German Landrace pigs.
Topics: Actomyosin; Adenosine Triphosphate; Animals; Calcium; Halothane; Magnesium; Malignant Hyperthermia; | 1980 |
[Malignant hyperthemia (author's transl)].
Topics: Anesthesia; Halothane; Humans; Japan; Malignant Hyperthermia | 1980 |
[Malignant hyperthermia. A case report (author's transl)].
Topics: Adolescent; Halothane; Heart Arrest; Hemorrhagic Disorders; Humans; Ice; Male; Malignant Hyperthermi | 1980 |
[Malignant hyperthermia. I. Observations in connection with its pathogenesis and course (author's transl)].
Topics: Anesthesia, General; Child, Preschool; Creatine Kinase; Electromyography; Female; Halothane; Humans; | 1980 |
Site of the muscle cell abnormality in swine susceptible to malignant hyperpyrexia.
Topics: Acetylcholine; Animals; Caffeine; Dantrolene; Halothane; In Vitro Techniques; Malignant Hyperthermia | 1980 |
[Morphology of the muscles and brain in case of malignant hyperthermia].
Topics: Adolescent; Anesthesia, Inhalation; Brain; Halothane; Humans; Male; Malignant Hyperthermia; Muscles | 1980 |
Malignant hyperthermia susceptibility. A light and electron microscopic study of endomyocardial biopsy specimens from nine patients.
Topics: Adolescent; Adult; Caffeine; Cardiomyopathies; Female; Halothane; Heart Diseases; Humans; Male; Mali | 1980 |
Cerebral metabolism during porcine malignant hyperthermia.
Topics: Animals; Brain; Cerebrovascular Circulation; Electroencephalography; Halothane; Lactates; Malignant | 1980 |
Modification of ryanodine toxicity by dantrolene and halothane in a model of malignant hyperthermia.
Topics: Alkaloids; Animals; Dantrolene; Diaphragm; Disease Models, Animal; Halothane; In Vitro Techniques; M | 1980 |
Halothane-induced malignant hyperthermia: creatine phosphate concentration in skeletal muscle as an early indicator of the onset of the syndrome.
Topics: Adenosine Triphosphate; Anesthesia, Intravenous; Animals; Glucosephosphates; Halothane; Lactates; Ma | 1980 |
[Serum myoglobin levels following administration of succinylcholine during nitrous oxide-oxygen-halothane anesthesia (author's transl)].
Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Child; Child, Preschool; Halothane; Humans; Maligna | 1980 |
Protection from halothane-induced porcine malignant hyperthermia syndrome by droperidol.
Topics: Animals; Animals, Laboratory; Dose-Response Relationship, Drug; Droperidol; Halothane; Malignant Hyp | 1980 |
Alterations of inositol polyphosphates in skeletal muscle during porcine malignant hyperthermia.
Topics: Anesthetics, Inhalation; Animals; Chromatography, High Pressure Liquid; Dantrolene; Disease Suscepti | 1995 |
The point mutation Arg615-->Cys in the Ca2+ release channel of skeletal sarcoplasmic reticulum is responsible for hypersensitivity to caffeine and halothane in malignant hyperthermia.
Topics: Amino Acid Sequence; Animals; Arginine; Blotting, Western; Caffeine; Calcium; Calcium Channels; Cell | 1994 |
Genotype and phenotype relationships for mutations in the ryanodine receptor in patients referred for diagnosis of malignant hyperthermia.
Topics: Anesthetics, Inhalation; Caffeine; Calcium Channels; Central Nervous System Stimulants; DNA Mutation | 1995 |
Cardiovascular and metabolic responses to anesthetic-induced malignant hyperthermia in swine.
Topics: Animals; Coronary Circulation; Halothane; Hemodynamics; Malignant Hyperthermia; Muscle, Skeletal; My | 1995 |
C1840-T mutation in the human skeletal muscle ryanodine receptor gene: frequency in northern German families susceptible to malignant hyperthermia and the relationship to in vitro contracture response.
Topics: Adolescent; Adult; Aged; Base Sequence; Caffeine; Calcium Channels; Child; Child, Preschool; Chromos | 1995 |
The effect of calcium channel antagonists and BAY K 8644 on calcium fluxes of malignant hyperpyrexia-susceptible muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
Malignant hyperthermia: halothane- and calcium-induced calcium release in skeletal muscle.
Topics: Animals; Calcium; Halothane; Horses; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Con | 1993 |
Abnormal action potential responses to halothane in heart muscle isolated from malignant hyperthermia-susceptible pigs.
Topics: Action Potentials; Animals; Caffeine; Dose-Response Relationship, Drug; Electric Stimulation; Haloth | 1995 |
Effect of cocaine on the contracture response to 1% halothane in patients undergoing diagnostic muscle biopsy for malignant hyperthermia.
Topics: Adult; Biopsy; Caffeine; Cocaine; Contracture; Disease Susceptibility; Female; Halothane; Humans; Ma | 1995 |
[Lack of sensitivity to per-anesthetic malignant hyperthermia in 32 patients who developed neuroleptic malignant syndrome].
Topics: Adolescent; Adult; Aged; Anesthesia, General; Caffeine; Contracture; Creatine Kinase; Dantrolene; Di | 1994 |
Discordance, in a malignant hyperthermia pedigree, between in vitro contracture-test phenotypes and haplotypes for the MHS1 region on chromosome 19q12-13.2, comprising the C1840T transition in the RYR1 gene.
Topics: Calcium Channels; Chromosomes, Human, Pair 19; Contracture; Disease Susceptibility; Female; Genetic | 1995 |
Incidence of malignant hyperthermia reactions in 2,214 patients undergoing muscle biopsy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Conduction; Anes | 1995 |
Lack of prophylactic or therapeutic efficacy of 5-HT2A receptor antagonists in halothane-induced porcine malignant hyperthermia.
Topics: Animals; Blood Pressure; Body Temperature; Dantrolene; Female; Halothane; Heart Rate; Ketanserin; Ma | 1994 |
Anesthesia-induced rigidity, unrelated to succinylcholine, associated with Smith-Lemli-Opitz syndrome and malignant hyperthermia.
Topics: Abnormalities, Multiple; Anesthesia; Child, Preschool; Diagnosis, Differential; Halothane; Humans; M | 1995 |
Malignant hyperthermia during sevoflurane administration.
Topics: Adult; Anesthetics; Caffeine; Disease Susceptibility; Ethers; Female; Halothane; Humans; Malignant H | 1995 |
Exercise induced hyperthermia in a racing greyhound.
Topics: Animals; Caffeine; Dog Diseases; Dogs; Exercise Test; Halothane; In Vitro Techniques; Male; Malignan | 1994 |
Transport of pigs different with respect to the halothane gene: stress assessment.
Topics: Animal Welfare; Animals; beta-Endorphin; Body Temperature; Female; Glycogen; Halothane; Heart Rate; | 1994 |
Co-segregation of the malignant hyperthermia and the Arg615-Cys615 mutation in the skeletal muscle calcium release channel protein in five European Landrace and Pietrain pig breeds.
Topics: Alleles; Animals; Base Sequence; Calcium Channels; DNA Primers; DNA, Satellite; Europe; Female; Geno | 1994 |
Effect of dantrolene treatment on muscle metabolism and meat quality of anesthetized pigs of different halothane genotypes.
Topics: Anesthesia; Animals; Biopsy, Needle; Calcium; Creatine; Dantrolene; Genotype; Glycogen; Halothane; H | 1994 |
Masseter muscle rigidity and malignant hyperthermia susceptibility in pediatric patients. An update on management and diagnosis.
Topics: Adolescent; Biopsy; Caffeine; Child; Child, Preschool; Creatine Kinase; Disease Susceptibility; Fema | 1994 |
Genetic effects on the variability of the halothane and caffeine muscle contracture tests.
Topics: Adult; Biopsy; Caffeine; Child; Disease Susceptibility; Family; Fatal Outcome; Female; Halothane; Hu | 1994 |
The effects of benzamil on in vitro contracture responses of human skeletal muscle to halothane.
Topics: Amiloride; Drug Interactions; Halothane; Humans; In Vitro Techniques; Kinetics; Malignant Hypertherm | 1994 |
The incidence of masseter muscle rigidity after succinylcholine in infants and children.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Child; Child, Preschool; Drug Interactions; Halotha | 1994 |
Viability criterion of muscle bundles used in the in vitro contracture test in patients with neuromuscular diseases.
Topics: Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Me | 1994 |
[The effect of anesthesia, of an alpha or beta adrenergic blockade in conscious and of adrenaline in anesthetized halothane-positive swine on hematologic and metabolic parameters in the blood during the course of halothane exposure].
Topics: Anesthesia; Animals; Epinephrine; Halothane; Male; Malignant Hyperthermia; Swine; Swine Diseases; Sy | 1994 |
Malignant hyperthermia--diagnostic dilemma: false-negative contracture responses with halothane and caffeine alone.
Topics: Caffeine; Child; False Negative Reactions; Female; Halothane; Humans; Male; Malignant Hyperthermia | 1994 |
Halothane concentrations for malignant hyperthermia testing.
Topics: Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia | 1994 |
Volatile anesthetics inhibit dihydropyridine binding to malignant hyperthermia-susceptible and normal pig skeletal muscle membranes.
Topics: Anesthetics; Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Dihydrop | 1994 |
Malignant hyperthermia and severe hypoglycemia after reexposure to halothane.
Topics: Child, Preschool; Dantrolene; Female; Halothane; Humans; Hypoglycemia; Liver; Malignant Hyperthermia | 1994 |
Rhabdomyolysis and acute renal failure in unsuspected malignant hyperpyrexia.
Topics: Acute Kidney Injury; Adult; Family; Halothane; Humans; Male; Malignant Hyperthermia; Rhabdomyolysis | 1993 |
A hypermetabolic reaction during anaesthesia and surgery. A case report.
Topics: Adult; Anesthesia, General; Halothane; Humans; Male; Malignant Hyperthermia | 1993 |
In vivo 31P NMR spectroscopy studies of halothane induced porcine stress syndrome. No effect of C-phenyl N-tert-butyl nitrone (PBN).
Topics: Animals; Cyclic N-Oxides; Free Radicals; Halothane; Magnetic Resonance Spectroscopy; Malignant Hyper | 1993 |
Metabolic response to halothane in piglets susceptible to malignant hyperthermia: an in vivo 31P-NMR study.
Topics: Adenosine Triphosphate; Anesthesia; Animals; Female; Glycogen; Glycolysis; Halothane; Hydrogen-Ion C | 1993 |
[Diagnosis of malignant hyperthermia susceptibility. 1. The significance of in vitro susceptibility tests].
Topics: Adult; Caffeine; Child; Child, Preschool; Disease Susceptibility; Halothane; Humans; In Vitro Techni | 1993 |
Improvement of brain electrical activity during treatment of porcine malignant hyperthermia with dantrolene.
Topics: Animals; Blood Pressure; Brain; Carbon Dioxide; Dantrolene; Electroencephalography; Halothane; Malig | 1993 |
[High purity ryanodine for in vitro diagnosis of malignant hyperthermia].
Topics: Adolescent; Adult; Caffeine; Child; Culture Techniques; Dose-Response Relationship, Drug; Female; Ha | 1993 |
Combined caffeine-halothane test for malignant hyperthermia.
Topics: Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction | 1993 |
False-negative results with muscle caffeine halothane contracture testing for malignant hyperthermia.
Topics: Adolescent; Adult; Biopsy; Caffeine; Child, Preschool; False Negative Reactions; Female; Halothane; | 1993 |
Relative accuracy of the halothane challenge test and a molecular genetic test in detecting the gene for porcine stress syndrome.
Topics: Animals; Breeding; Calcium Channels; Disease Susceptibility; DNA; Female; Genotype; Halothane; Male; | 1993 |
Detection of the ryanodine receptor mutation associated with malignant hyperthermia in purebred swine populations.
Topics: Alleles; Animals; Base Sequence; Breeding; Calcium Channels; DNA; Gene Frequency; Genotype; Halothan | 1993 |
Phenotypes associated with malignant hyperthermia susceptibility in swine genotyped as homozygous or heterozygous for the ryanodine receptor mutation.
Topics: Animals; Base Sequence; Calcium; Calcium Channels; Disease Susceptibility; Genotype; Halothane; Hete | 1993 |
In vitro effect of ephedrine, adrenaline, noradrenaline and isoprenaline on halothane-induced contractures in skeletal muscle from patients potentially susceptible to malignant hyperthermia.
Topics: Dose-Response Relationship, Drug; Drug Synergism; Ephedrine; Epinephrine; Halothane; Humans; In Vitr | 1993 |
Improved noninvasive diagnostic testing for malignant hyperthermia susceptibility from a combination of metabolites determined in vivo with 31P-magnetic resonance spectroscopy.
Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Disease Susceptibility; Female; Halothane; Humans; Magnet | 1993 |
Comparison of in vitro contracture testing with ryanodine, halothane and caffeine in malignant hyperthermia and other neuromuscular disorders.
Topics: Caffeine; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Tech | 1993 |
Delayed onset of malignant hyperthermia induced by isoflurane and desflurane compared with halothane in susceptible swine.
Topics: Anesthetics; Animals; Desflurane; Disease Susceptibility; Halothane; Isoflurane; Malignant Hyperther | 1993 |
On the nature of the link between malignant hyperthermia and exertional heatstroke.
Topics: Animals; Body Temperature Regulation; Caffeine; Calcium Channels; Disease Models, Animal; Disease Su | 1995 |
Malignant hyperthermia in the otology patient: the UCLA experience.
Topics: Administration, Inhalation; Adult; Anesthetics; Caffeine; Child; Child, Preschool; Dantrolene; Femal | 1994 |
Comparison of the segregation of the RYR1 C1840T mutation with segregation of the caffeine/halothane contracture test results for malignant hyperthermia susceptibility in a large Manitoba Mennonite family.
Topics: Anesthetics, Inhalation; Caffeine; Disease Susceptibility; Female; Halothane; Heterozygote; Humans; | 1996 |
Caffeine-halothane accuracy in MH testing.
Topics: Caffeine; Drug Stability; Drug Storage; Halothane; Humans; Malignant Hyperthermia | 1995 |
Thermal response in acute porcine malignant hyperthermia.
Topics: Acute Disease; Animals; Body Temperature Regulation; Halothane; Malignant Hyperthermia; Muscles; Ski | 1996 |
Norepinephrine does not potentiate porcine malignant hyperthermia.
Topics: Animals; Blood Pressure; Epinephrine; Halothane; Heart Rate; Hydrogen-Ion Concentration; Malignant H | 1996 |
Prior hypothermia attenuates malignant hyperthermia in susceptible swine.
Topics: Animals; Halothane; Hemodynamics; Hypothermia, Induced; Malignant Hyperthermia; Succinylcholine; Swi | 1996 |
Effects of the serotonin2 receptor agonist DOI on skeletal muscle specimens from malignant hyperthermia-susceptible patients.
Topics: Adolescent; Adult; Aged; Amphetamines; Animals; Cattle; Child; Child, Preschool; Halothane; Humans; | 1996 |
Malignant hyperthermia suggestive hypermetabolic syndrome at emergence from anesthesia.
Topics: Caffeine; Child; Creatine Kinase; Diagnosis, Differential; Female; Halothane; Humans; Malignant Hype | 1995 |
Malignant hyperthermia (MH) diagnostics: a comparison between the halothane-caffeine- and the ryanodine-contracture-test results in MH susceptible, normal and control muscle.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Child; Halothane; Humans; In Vitro Techn | 1996 |
Altered sodium current response to intracellular fatty acids in halothane-hypersensitive skeletal muscle.
Topics: Aging; Disease Susceptibility; Electric Conductivity; Fatty Acids; Halothane; Humans; Intracellular | 1996 |
[Atypical malignant hyperthermia. A higher incidence than expected].
Topics: Anesthetics, Inhalation; Child, Preschool; Female; Flushing; Halothane; Humans; Incidence; Malignant | 1996 |
Malignant hyperthermia.
Topics: Anesthesia, General; Caffeine; Counseling; Disease Susceptibility; Halothane; Humans; Malignant Hype | 1996 |
Effects of the 5-HT2 receptor antagonist ritanserin on halothane-induced increase of inositol phosphates in porcine malignant hyperthermia.
Topics: Anesthetics, Inhalation; Animals; Halothane; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Mali | 1996 |
[Are monamine oxidase inhibitors in disposition to malignant hyperthermia contraindicated? Discussion based on a case report].
Topics: Anesthetics, Inhalation; Attention Deficit Disorder with Hyperactivity; Benzamides; Child; Contraind | 1996 |
[Definition of a diagnostic score of malignant hyperthermia using P-31 magnetic resonance spectroscopy].
Topics: Caffeine; Contracture; Disease Susceptibility; Halothane; Humans; Magnetic Resonance Spectroscopy; M | 1996 |
Reduced Mg2+ inhibition of Ca2+ release in muscle fibers of pigs susceptible to malignant hyperthermia.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Dantrolene; Genetic Predisposition to Disease; | 1997 |
An analysis of the predictive probability of the in vitro contracture test for determining susceptibility to malignant hyperthermia.
Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Child; Contracture; Disease Susceptibility; Halothane; Hu | 1997 |
Malignant hyperthermia testing in patients with persistently increased serum creatine kinase levels.
Topics: Adolescent; Adult; Anesthetics, Inhalation; Biopsy, Needle; Caffeine; Child; Child, Preschool; Clini | 1997 |
Recombination between the postulated CCD/MHE/MHS locus and RYR1 gene markers.
Topics: Alleles; Caffeine; Calcium Channels; Child, Preschool; Chromosomes, Human, Pair 19; Female; Genetic | 1996 |
Classification of malignant hyperthermia-equivocal patients by 4-chloro-M-cresol.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Cresols; Disease Susceptibility; Dose-Re | 1997 |
Clinical reassessment of malignant hyperthermia in Abitibi-Témiscamingue.
Topics: Adolescent; Adult; Caffeine; Child; Disease Susceptibility; Family Characteristics; Female; Halothan | 1997 |
Malignant hyperthermia susceptibility, an autosomal dominant disorder?
Topics: Adolescent; Adult; Caffeine; Calcium Channels; Child; Child, Preschool; Female; Genes, Dominant; Gen | 1997 |
[Effect of chlorocresol vs caffeine on muscle contracture in malignant hyperthermia susceptible patients].
Topics: Adolescent; Adult; Caffeine; Cresols; Disease Susceptibility; Halothane; Humans; In Vitro Techniques | 1997 |
Dystrophin deficient mdx muscle is not prone to MH susceptibility: an in vitro study.
Topics: Anesthetics, Inhalation; Animals; Caffeine; Disease Susceptibility; Dystrophin; Halothane; Male; Mal | 1997 |
In vitro contracture test for diagnosis of malignant hyperthermia following the protocol of the European MH Group: results of testing patients surviving fulminant MH and unrelated low-risk subjects. The European Malignant Hyperthermia Group.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia; Biopsy; Caffeine; Child; Child, Preschool; F | 1997 |
4-Chloro-m-cresol test--a possible supplementary test for diagnosis of malignant hyperthermia susceptibility.
Topics: Biopsy; Caffeine; Cresols; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Huma | 1997 |
Caffeine and halothane sensitivity of intracellular Ca2+ release is altered by 15 calcium release channel (ryanodine receptor) mutations associated with malignant hyperthermia and/or central core disease.
Topics: Animals; Caffeine; Calcium; Cell Line; DNA, Complementary; Halothane; Humans; Malignant Hyperthermia | 1997 |
Reduced inhibitory effect of Mg2+ on ryanodine receptor-Ca2+ release channels in malignant hyperthermia.
Topics: Animals; Binding Sites; Biophysical Phenomena; Biophysics; Caffeine; Calcium; Halothane; Humans; In | 1997 |
Evaluation for malignant hyperthermia susceptibility in black-tailed deer.
Topics: Anesthetics, Inhalation; Animals; Blood Gas Analysis; Cardiac Output; Deer; Disease Susceptibility; | 1996 |
Histological support for the difference between malignant hyperthermia susceptible (MHS), equivocal (MHE) and negative (MHN) muscle biopsies.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Atrophy; Biopsy; Disease Susceptibility; Female; H | 1997 |
The Israeli Diagnostic Center for Malignant Hyperthermia: 7-years' accumulated experience.
Topics: Academies and Institutes; Adult; Aged; Biopsy; Caffeine; Child; Electromyography; Female; Genetic Pr | 1997 |
Muscle biopsy for malignant hyperthermia screening in children.
Topics: Adolescent; Anesthetics, Inhalation; Biopsy; Caffeine; Central Nervous System Stimulants; Child; Dis | 1997 |
Generalized muscle rigidity and hypercarbia with halothane and isoflurane.
Topics: Carbon Dioxide; Child, Preschool; Contracture; Female; Halothane; Humans; Isoflurane; Malignant Hype | 1998 |
Intracellular calcium homeostasis in human primary muscle cells from malignant hyperthermia-susceptible and normal individuals. Effect Of overexpression of recombinant wild-type and Arg163Cys mutated ryanodine receptors.
Topics: Arginine; Blotting, Western; Calcium; Cells, Cultured; Cloning, Molecular; Cystine; DNA, Complementa | 1998 |
Effects of veratridine on mechanical responses of human malignant hyperthermic muscle fibers.
Topics: Calcium; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Sodium | 1998 |
Discordance between malignant hyperthermia susceptibility and RYR1 mutation C1840T in two Scandinavian MH families exhibiting this mutation.
Topics: Anesthesia; Caffeine; Denmark; Female; Genetic Predisposition to Disease; Halothane; Humans; Male; M | 1997 |
The sensitivity and specificity of the caffeine-halothane contracture test: a report from the North American Malignant Hyperthermia Registry. The North American Malignant Hyperthermia Registry of MHAUS.
Topics: Adult; Caffeine; Contracture; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hypert | 1998 |
A rat model of spontaneous myopathy and malignant hyperthermia.
Topics: Animals; Brain; Disease Models, Animal; Halothane; Immunohistochemistry; Malignant Hyperthermia; Mic | 1998 |
Rhabdomyolysis after infection and taking a cold medicine in a patient who was susceptible to malignant hyperthermia.
Topics: Adult; Caffeine; Chlorpheniramine; Common Cold; Dantrolene; Halothane; Humans; In Vitro Techniques; | 1998 |
Rhabdomyolysis following severe physical exercise in a patient with predisposition to malignant hyperthermia.
Topics: Adult; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Disease Susceptibility; | 1998 |
Human malignant hyperthermia associated with desflurane anesthesia.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Child; Child, Preschool; Dantrolene; Databases as | 1998 |
Delayed onset malignant hyperthermia in two pigs.
Topics: Animals; Blood Gas Analysis; Fatal Outcome; Female; Halothane; Malignant Hyperthermia; Swine; Swine | 1998 |
Treatment of normal skeletal muscle with FK506 or rapamycin results in halothane-induced muscle contracture.
Topics: Adolescent; Adult; Anesthetics, Inhalation; Calcium; Carrier Proteins; Child; Child, Preschool; DNA- | 1998 |
Malignant hyperthermia and neuroleptic malignant syndrome in a patient during treatment for acute asthma.
Topics: Acute Disease; Adjuvants, Anesthesia; Adult; Anesthetics, Inhalation; Asthma; Bronchodilator Agents; | 1999 |
Can pale, soft, exudative pork be prevented by postmortem sodium bicarbonate injection?
Topics: Animals; Body Temperature; Female; Halothane; Hydrogen-Ion Concentration; Malignant Hyperthermia; Me | 1998 |
Mutation screening of the RYR1 gene and identification of two novel mutations in Italian malignant hyperthermia families.
Topics: Caffeine; DNA Primers; Female; Halothane; Humans; Italy; Male; Malignant Hyperthermia; Muscles; Myop | 1999 |
Eltanolone (5-beta-pregnanolone) does not trigger, and attenuates halothane triggering of, malignant hyperthermia in malignant hyperthermia susceptible swine.
Topics: Anesthetics, Inhalation; Animals; Body Temperature; Capnography; Drug Antagonism; Electrocardiograph | 1999 |
Effects of the halothane genotype and slaughter weight on texture of pork.
Topics: Anesthetics, Inhalation; Animals; Body Weight; Female; Food Technology; Genotype; Halothane; Male; M | 1999 |
[Malignant hyperthermia: difficulty in diagnosing susceptibility in Spain].
Topics: Anesthetics, Inhalation; Caffeine; Europe; Genetic Predisposition to Disease; Halothane; Humans; Inf | 1999 |
ATX II, a sodium channel toxin, sensitizes skeletal muscle to halothane, caffeine, and ryanodine.
Topics: Animals; Caffeine; Cnidarian Venoms; Female; Halothane; Humans; Male; Malignant Hyperthermia; Muscle | 1999 |
Comparison between the European and North American protocols for diagnosis of malignant hyperthermia susceptibility in humans.
Topics: Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Sensitivity and Specificity | 1999 |
Signs of an MH reaction.
Topics: Adjuvants, Anesthesia; Anesthetics, Inhalation; Atropine; Carbon Dioxide; Child; Fasciculation; Halo | 1999 |
Inhalation anesthetics and Duchenne's muscular dystrophy.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Contraindications; Disease Susceptibility; Haloth | 1999 |
Factitious halothane detection during trigger-free anesthesia in a malignant hyperthermia susceptible patient.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Arthrodesis; Arthroscopy; Disease Susceptibilit | 1999 |
Effects of halothane on mechanical response of skeletal muscle from malignant hyperthermia susceptible patients.
Topics: Anesthetics, Inhalation; Biopsy; Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techn | 1998 |
Abnormal regulation of muscle contraction in horses with recurrent exertional rhabdomyolysis.
Topics: Anesthetics, Inhalation; Animals; Biopsy; Caffeine; Central Nervous System Stimulants; Female; Halot | 1999 |
Caffeine- or halothane-induced contractures of masseter muscle are similar to those of vastus muscle in normal humans.
Topics: Aged; Aged, 80 and over; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Contr | 1999 |
Hemodynamic and metabolic manifestations of acute endotoxin infusion in pigs with and without the malignant hyperthermia mutation.
Topics: Animals; Calcium; Endotoxemia; Halothane; Hemodynamics; Malignant Hyperthermia; Mutation; Succinylch | 1999 |
Xenon does not trigger malignant hyperthermia in susceptible swine.
Topics: Amino Acid Substitution; Anesthesia, General; Anesthetics, Inhalation; Animals; Arginine; Blood Pres | 1999 |
5-HT2 receptor antagonist-mediated inhibition of halothane-induced contractures in skeletal muscle specimens from malignant hyperthermia susceptible patients.
Topics: Adolescent; Adult; Anesthetics, Inhalation; Caffeine; Child; Dose-Response Relationship, Drug; Drug | 1999 |
A halothane test to detect turkeys prone to developing pale, soft, and exudative meat.
Topics: Adenosine; Animals; Color; Food Technology; Halothane; Hydrogen-Ion Concentration; Inosine; Male; Ma | 1999 |
Isoform-specific interactions between halothane and the ryanodine receptor Ca(2+)-release channel: implications for malignant hyperthermia and the protein theory of anaesthetic action.
Topics: Anesthesia, Inhalation; Animals; Halothane; Humans; Malignant Hyperthermia; Models, Chemical; Protei | 1999 |
Shortening velocity of skeletal muscle from humans with malignant hyperthermia susceptibility: effects of halothane.
Topics: Anesthetics, Inhalation; Biomechanical Phenomena; Halothane; Humans; In Vitro Techniques; Kinetics; | 2000 |
In vivo whole-body resting energy expenditure and insulin action in human malignant hyperthermia.
Topics: Adult; Anesthetics, Inhalation; Basal Metabolism; Body Composition; Caffeine; Calorimetry, Indirect; | 2000 |
A novel ryanodine receptor mutation and genotype-phenotype correlation in a large malignant hyperthermia New Zealand Maori pedigree.
Topics: Amino Acid Sequence; Anesthetics, Inhalation; Chromosomes, Human, Pair 19; DNA Mutational Analysis; | 2000 |
Between-center variability of results of the in vitro contracture test for malignant hyperthermia susceptibility.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Biopsy; Caffeine; Female; Genetic Predisposition t | 2000 |
Inositol 1,4,5-trisphosphate synthesis in mononuclear white blood cells of malignant hyperthermia-susceptible and normal human beings, following in vitro exposure to halothane, caffeine and ryanodine.
Topics: Anesthetics, Inhalation; Caffeine; Cell Separation; Halothane; Humans; In Vitro Techniques; Inositol | 2000 |
[Malignant hyperthermia susceptibility in 3 patients with malignant neuroleptic syndrome].
Topics: Adult; Caffeine; Contracture; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hyp | 2000 |
Altered expression of cardiac myosin isozymes associated with the malignant hyperthermia genotype in swine.
Topics: Adenosine Triphosphatases; Anesthetics, Inhalation; Animals; Calcium; Gene Expression; Genetic Predi | 2000 |
An autosomal dominant congenital myopathy with cores and rods is associated with a neomutation in the RYR1 gene encoding the skeletal muscle ryanodine receptor.
Topics: Amino Acid Substitution; Caffeine; Calcium; Cell Line; DNA Mutational Analysis; Female; France; Gene | 2000 |
Xenon does not induce contracture in human malignant hyperthermia muscle.
Topics: Anesthetics, Inhalation; Caffeine; Culture Techniques; Dose-Response Relationship, Drug; Drug Evalua | 2000 |
Evidence for susceptibility to malignant hyperthermia in patients with exercise-induced rhabdomyolysis.
Topics: Adolescent; Adult; Anesthetics, Inhalation; Case-Control Studies; Child; Disease Susceptibility; Exe | 2001 |
Halothane, dental anaesthesia and children.
Topics: Anesthesia, Dental; Anesthetics, Inhalation; Arrhythmias, Cardiac; Child; Halothane; Humans; Maligna | 2000 |
Homozygous and heterozygous Arg614Cys mutations (1840C-->T) in the ryanodine receptor gene co-segregate with malignant hyperthermia susceptibility in a German family.
Topics: Adult; Anesthetics, Inhalation; Caffeine; DNA Mutational Analysis; Female; Genetic Predisposition to | 2001 |
A noninvasive investigation of muscle energetics supports similarities between exertional heat stroke and malignant hyperthermia.
Topics: Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Energy Metabolism; Halothane; | 2001 |
Prolonging viability of swine muscle biopsy specimens in malignant hyperthermia testing.
Topics: Anesthetics, Inhalation; Animals; Caffeine; Central Nervous System Stimulants; Cold Temperature; Ele | 2001 |
Congenital myopathy with central cores and fingerprint bodies in association with malignant hyperthermia susceptibility.
Topics: Adult; Anesthetics, Inhalation; Biopsy; Caffeine; Central Nervous System Stimulants; Halothane; Huma | 2001 |
Determination of a positive malignant hyperthermia (MH) disposition without the in vitro contracture test in families carrying the RYR1 Arg614Cys mutation.
Topics: Caffeine; DNA; DNA Mutational Analysis; Family Health; Female; Halothane; Humans; Male; Malignant Hy | 2001 |
Autosomal dominant canine malignant hyperthermia is caused by a mutation in the gene encoding the skeletal muscle calcium release channel (RYR1).
Topics: Amino Acid Sequence; Animals; Dog Diseases; Dogs; Female; Genotype; Halothane; In Vitro Techniques; | 2001 |
Vitamin-mineral supplementation and accelerated chilling effects on quality of pork from pigs that are monomutant or noncarriers of the halothane gene.
Topics: Animals; Cold Temperature; Color; Female; Food Handling; Halothane; Heterozygote; Male; Malignant Hy | 2001 |
Testing for malignant hyperthermia.
Topics: Anesthesia; Biopsy; Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Sensiti | 2002 |
The differential effect of halothane and 1,2-dichlorohexafluorocyclobutane on in vitro muscle contractures of patients susceptible to malignant hyperthermia.
Topics: Adult; Aged; Anesthetics; Anesthetics, Inhalation; Chlorofluorocarbons; Cyclobutanes; Female; Geneti | 2002 |
Creatine monohydrate supplementation and the quality of fresh pork in normal and halothane carrier pigs.
Topics: Animal Feed; Animals; Body Temperature; Cooking; Creatine; Dietary Supplements; Female; Genotype; Ha | 2002 |
Mutation screening in the ryanodine receptor 1 gene (RYR1) in patients susceptible to malignant hyperthermia who show definite IVCT results: identification of three novel mutations.
Topics: Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Genetic Testing; Halothane; Hu | 2002 |
'Picture frame' fibres in a carrier of the trait for malignant hyperpyrexia.
Topics: Adenosine Triphosphatases; Adult; Calcium; Halothane; Heterozygote; Histocytochemistry; Humans; Hydr | 1975 |
Porcine malignant hyperthermia induced by halothane and succinylcholine: failure of treatment with procaine or procainamide.
Topics: Animals; Catecholamines; Halothane; Hydrogen-Ion Concentration; Lactates; Malignant Hyperthermia; Po | 1976 |
A laboratory animal model for malignant hyperpyrexia.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Caffeine; Disease Models, Animal; Drug Interactions; Halo | 1979 |
Letter: Malignant hyperpyrexia.
Topics: Acidosis; Calcium; Catecholamines; Halothane; Humans; Insulin; Insulin Secretion; Malignant Hyperthe | 1975 |
[A case of malignant hyperthermia, in a child, induced by an anesthetic].
Topics: Child; Halothane; Humans; Hyalin; Male; Malignant Hyperthermia; Muscles; Succinylcholine | 1977 |
Morphological and biochemical defects in muscles of human carriers of the malignant hyperthermia syndrome.
Topics: Actomyosin; Adenosine Triphosphatases; Adenosine Triphosphate; Adolescent; Calcium; Carrier State; C | 1975 |
Porcine malignant hyperthermia: effects of halothane on mitochondrial respiration and calcium accumulation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Body Weight; Calcium; | 1975 |
Behavioural and pituitary-adrenal characteristics of pigs differing by their susceptibility to the malignant hyperthermia syndrome induced by halothane anesthesia. 2. Pituitary-adrenal function.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Exploratory Behavior; Female; Halotha | 1978 |
[The effect of halothane anesthesia on the function of the adrenal cortex and some metabolites in the blood plasma of pigs not susceptible to malignant hyperthermia].
Topics: 11-Hydroxycorticosteroids; Adrenal Cortex; Adrenocorticotropic Hormone; Anesthesia, Inhalation; Anim | 1979 |
Procaine in porcine malignant hyperthermia.
Topics: Animals; Body Temperature; Creatine Kinase; Halothane; Hydrogen-Ion Concentration; Injections, Intra | 1975 |
Calcium uptake into muscle of pigs susceptible to malignant hyperthermia: in vitro and in vivo studies with and without halothane.
Topics: Anesthesia, Inhalation; Animals; Calcium; Halothane; Hydrogen-Ion Concentration; In Vitro Techniques | 1975 |
Malignant hyperthermia.
Topics: Alleles; Anesthesia, General; Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscles | 1978 |
Malignant hyperthermia.
Topics: Anesthesia, Dental; Child, Preschool; Creatine Kinase; Female; Halothane; Humans; Malignant Hyperthe | 1979 |
[Halothane-induced malignant hyperthermia. Report of successful treatment of 2 patients].
Topics: Adult; Cryotherapy; Halothane; Humans; Infant; Male; Malignant Hyperthermia | 1979 |
Rationale for dantrolene vs. procainamide for treatment of malignant hyperthermia.
Topics: Animals; Dantrolene; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Halothane; Hy | 1979 |
Identification of susceptibility to malignant hyperpyrexia in swine.
Topics: Animals; Caffeine; Disease Models, Animal; Dose-Response Relationship, Drug; Halothane; In Vitro Tec | 1979 |
Malignant hyperthermia.
Topics: Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscles | 1979 |
In vivo neutron activation analysis for bone calcium (INVAA) in malignant hyperthermia susceptible patients.
Topics: Adult; Age Factors; Bone and Bones; Caffeine; Calcium; Female; Halothane; Humans; Male; Malignant Hy | 1979 |
Althesin as an anaesthetic in experimental animals susceptible to halothane-initiated malignant hyperthermia [proceedings].
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Halothane; Malignant Hyperthermia; Swine | 1979 |
Skeletal muscle sarcoplasmic reticulum in porcine malignant hyperthermia.
Topics: Animals; Calcium; Halothane; In Vitro Techniques; Kinetics; Malignant Hyperthermia; Sarcoplasmic Ret | 1979 |
Mitochondrial calcium, erythrocyte fragility and porcine malignant hyperthermia.
Topics: Animals; Calcium; Erythrocytes; Halothane; Hemoglobins; Kinetics; Malignant Hyperthermia; Mitochondr | 1979 |
Does prior dantrolene affect the in vitro diagnosis of malignant hyperthermia susceptibility?
Topics: Animals; Biopsy; Caffeine; Dantrolene; Drug Interactions; Halothane; In Vitro Techniques; Malignant | 1979 |
Drug reactions and interactions in the patient undergoing surgery.
Topics: Anesthetics; Barbiturates; Butyrylcholinesterase; Drug Interactions; Drug-Related Side Effects and A | 1979 |
Malignant hyperthermia: diagnosis, treatment and investigations of a skeletal muscle lesion.
Topics: Anesthetics; Animals; Caffeine; Diagnosis, Differential; Disease Models, Animal; Halothane; Humans; | 1979 |
[Blood characteristics of some french pig populations. Relationships with the malignant hyperthermia syndrome (author's transl)].
Topics: Anesthesia; Animals; Blood Glucose; Creatine Kinase; Female; Halothane; Lactates; Male; Malignant Hy | 1979 |
Close linkage established between the HAL locus for halothane sensitivity and the PHI (phosphohexose isomerase) locus in pigs of the Danish Landrace breed.
Topics: Anesthesia, Inhalation; Animals; Drug Hypersensitivity; Genetic Linkage; Genotype; Glucose-6-Phospha | 1977 |
Malignant hyperthermia in a Greyhound.
Topics: Anesthesia, Inhalation; Animals; Dog Diseases; Dogs; Halothane; Male; Malignant Hyperthermia; Succin | 1978 |
The role of the sympathetic nervous system in the pathogenesis of halothane-induced malignant hyperthermia in the pietrain pig [proceedings].
Topics: Adrenalectomy; Animals; Halothane; Malignant Hyperthermia; Swine; Sympathetic Nervous System | 1978 |
Porcine malignant hyperthermia. VI: the effects of bilateral adrenalectomy and pretreatment with bretylium on the halothane-induced response.
Topics: Adrenalectomy; Anesthesia, General; Animals; Bretylium Compounds; Bretylium Tosylate; Halothane; Mal | 1978 |
Would morphine in large doses prevent malignant hyperthermia?
Topics: Animals; Halothane; Humans; Malignant Hyperthermia; Morphine; Swine | 1978 |
Effect of halothane on the rate of acid production, lactate production and pyruvate dehydrogenase activity of malignant hyperpyrexia human muscle.
Topics: Acids; Halothane; Humans; In Vitro Techniques; Lactates; Malignant Hyperthermia; Muscles; Pyruvate D | 1978 |
[Malignant hyperthermia in a black child. A case report].
Topics: Child; Creatine Kinase; Cryosurgery; Halothane; Humans; Hydrocortisone; In Vitro Techniques; Male; M | 1978 |
Perfusion of malignant hyperthermia susceptible and normal isolated pig livers with halothane.
Topics: Anesthesia, Inhalation; Animals; Body Temperature; Carbon Dioxide; Halothane; Lactates; Liver; Malig | 1978 |
Behavioural and pituitary-adrenal characteristics of pigs differing by their susceptibility to the malignant hyperthermia syndrome induced by halothane anesthesia. 1. Behavioural measures.
Topics: Animals; Avoidance Learning; Behavior, Animal; Exploratory Behavior; Female; Halothane; Learning; Ma | 1978 |
Further evidence for the existence of the [PHIA, HALn] haplotype in the Landrace breed.
Topics: Animals; Blood Group Antigens; Genes; Genetic Linkage; Glucose-6-Phosphate Isomerase; Halothane; Mal | 1978 |
[Histological, histochemical, and ultrastructural findings in malignant hyperthermia (author's transl)].
Topics: Adult; Autopsy; Cyanosis; Halothane; Histocytochemistry; Humans; Male; Malignant Hyperthermia; Micro | 1975 |
Porcine malignant hyperthermia: role of skeletal muscle in increased oxygen consumption.
Topics: Animals; Halothane; Malignant Hyperthermia; Muscles; Oxygen Consumption; Succinylcholine; Swine | 1977 |
Screening for malignant hyperpyrexia.
Topics: Caffeine; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Techniques; Malignant Hypert | 1977 |
The prophylaxis of malignant hyperthermia by oral dantrolene sodium in swine.
Topics: Administration, Oral; Anesthesia, General; Anesthesia, Inhalation; Animals; Dantrolene; Halothane; H | 1977 |
The malignant hyperthermia syndrome: an unusual complication of anesthesia.
Topics: Anesthesia, General; Appendectomy; Child; Halothane; Heart Arrest; Humans; Male; Malignant Hyperther | 1977 |
Inheritance of reaction to halothane anaesthesia in pigs.
Topics: Animals; Genes, Recessive; Halothane; Malignant Hyperthermia; Swine; Swine Diseases | 1977 |
Role of sympathetic activity in porcine malignant hyperthermia.
Topics: Acidosis; Acidosis, Respiratory; Anesthesia, Conduction; Anesthesia, Spinal; Animals; Catecholamines | 1977 |
Anaesthesia for patients susceptible to malignant hyperpyrexia. A study of pancuronium and methylprednisolone.
Topics: Anesthesia; Contracture; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Techniques; M | 1977 |
Malignant hyperthermia in a parturient Poland China sow.
Topics: Animals; Female; Halothane; Malignant Hyperthermia; Pregnancy; Pregnancy Complications; Swine | 1977 |
Suxamethonium-induced porcine malignant hyperthermia.
Topics: Animals; Halothane; Lactates; Malignant Hyperthermia; Muscles; Oxygen Consumption; Succinylcholine; | 1976 |
[Report on 2 cases of malignant hyperthermia with different clinical courses].
Topics: Adult; Clinical Enzyme Tests; Creatine Kinase; Halothane; Humans; L-Lactate Dehydrogenase; Male; Mal | 1976 |
[Mild form of malignant hyperthermia? OR, ABNORMAL REACTION To succinyldicholine?].
Topics: Body Temperature; Child; Child, Preschool; Halothane; Humans; Malignant Hyperthermia; Neuroleptanalg | 1976 |
Malignant hyperthermia in Belgian Landrace pigs rested or exercised before exposure to halothane.
Topics: Animals; Blood Glucose; Calcium; Creatine Kinase; Disease Models, Animal; Glycogen; Halothane; Heart | 1976 |
Phosphohexose isomerase (PHI) and porcine halothane sensitivity.
Topics: Anesthesia, Inhalation; Animals; Blood Group Antigens; Glucose-6-Phosphate Isomerase; Halothane; Mal | 1976 |
The adenosine triphosphate (ATP) depletion test: comparison with the caffeine contracture test as a method of diagnosing malignant hyperthermia susceptibility.
Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Biopsy; Caffeine; Carbon Dioxide; Child; Dose-Respo | 1976 |
Clinical management of malignant hyperpyrexia.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Halothane; Heart Arrest; Humans; Male; Mal | 1976 |
[Case of malignant hyperthermia].
Topics: Adult; Anesthesia, Inhalation; Bronchiectasis; Halothane; Humans; Male; Malignant Hyperthermia; Nitr | 1976 |
Porcine malignant hyperthemia IV: Neuromuscular blockade.
Topics: Animals; Halothane; Malignant Hyperthermia; Neuromuscular Junction; Pancuronium; Succinylcholine; Sw | 1976 |
[Malignant hyperthermia in Belgian landrace pigs].
Topics: Anesthesia, Inhalation; Animals; Halothane; Malignant Hyperthermia; Muscle Contraction; Muscles; Phy | 1976 |
Letter: Procaine for malignant hyperthermia.
Topics: Animals; Calcium; Disease Models, Animal; Halothane; Humans; Malignant Hyperthermia; Procaine; Sarco | 1975 |
Porcine malignant hyperthermia: effects of temperature and extracellular calcium concentration on halothane-induced contracture of susceptible skeletal muscle.
Topics: Animals; Caffeine; Calcium; Dose-Response Relationship, Drug; Halothane; In Vitro Techniques; Malign | 1975 |
Prevention of porcine malignant hyperthermia by epidural block.
Topics: Anesthesia, Epidural; Animals; Body Temperature; Central Nervous System; Female; Halothane; Lidocain | 1975 |
[Malignant hyperthermia].
Topics: Anesthesia, General; Anesthetics; Halothane; Humans; Male; Malignant Hyperthermia; Succinylcholine | 1975 |
Letter: New causes of malignant hyperpyrexia.
Topics: Anesthesia, Inhalation; Halothane; Humans; Malignant Hyperthermia | 1975 |
Letter: Althesin and malignant hyperthermia.
Topics: Alfaxalone Alfadolone Mixture; Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Catecholami | 1975 |
Letter: New causes of malignant hyperpyrexia.
Topics: Anesthesia, Inhalation; Drug Contamination; Halothane; Humans; Malignant Hyperthermia; Nitrous Oxide | 1975 |
Age dependent variation of serum creatine phosphokinase levels in pigs.
Topics: Age Factors; Animals; Creatine Kinase; Female; Halothane; Male; Malignant Hyperthermia; Swine | 1975 |
An unusual case of malignant hyperpyrexia. First reported case in a South African negro.
Topics: Anesthesia, General; Black or African American; Black People; Body Temperature; Creatine Kinase; Hal | 1975 |
An evaluation of procaine in the treatment of malignant hyperpyrexia.
Topics: Anesthesia, General; Animals; Caffeine; Contracture; Dose-Response Relationship, Drug; Drug Evaluati | 1975 |
Control of the malignant hyperpyrexic syndrome in MHS swine by dantrolene sodium.
Topics: Anesthesia, General; Animals; Dantrolene; Halothane; Hydantoins; Malignant Hyperthermia; Mannitol; S | 1975 |
Total calcium content of skeletal muscle isolated from humans and pigs susceptible to malignant hyperthermia.
Topics: Animals; Calcium; Contracture; Halothane; Humans; Male; Malignant Hyperthermia; Mitochondria, Muscle | 1975 |
Editorial: Malignant hyperthermia.
Topics: Adult; Aged; Anesthesia, General; Anesthesia, Inhalation; Halothane; Humans; Infant; Malignant Hyper | 1975 |
[Malignant hyperthermia due to general anesthesia. Diagnosis and treatment].
Topics: Anesthesia, General; Anesthesia, Inhalation; Arrhythmias, Cardiac; Child, Preschool; Creatine Kinase | 1975 |
Evaluation of creatinine phosphokinase in screening patients for malignant hyperpyrexia.
Topics: Creatine Kinase; Evaluation Studies as Topic; Halothane; Humans; In Vitro Techniques; Malignant Hype | 1975 |
[Malignant hyperthermia following nitrous oxide-halothane anesthesia].
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Anesthesia, Inhalation; Child, Preschool; Female; Halot | 1975 |
Proceedings: The metabolic course of porcine malignant hyperthermia.
Topics: Animals; Carbon Dioxide; Catecholamines; Halothane; Lactates; Malignant Hyperthermia; Potassium; Suc | 1975 |
Postoperative fever and the halothane controversy.
Topics: Anesthesia, General; Chemical and Drug Induced Liver Injury; Fever; Halothane; Humans; Malignant Hyp | 1975 |
Halothane-induced porcine malignant hyperthermia: metabolic and hemodynamic changes.
Topics: Animals; Carbon Dioxide; Cardiac Output; Epinephrine; Halothane; Hemodynamics; Lactates; Malignant H | 1976 |
Porcine malignant hyperthermia: effect of dantrolene sodium on in-vitro halothane-induced contraction of susceptible muscle.
Topics: Animals; Caffeine; Calcium; Contracture; Dantrolene; Halothane; Hydantoins; In Vitro Techniques; Mal | 1976 |
Role of hypertension in fulminant hyperthermia-stress syndrome.
Topics: Animals; Blood Flow Velocity; Cardiac Output; Halothane; Hypertension; Malignant Hyperthermia; Swine | 1976 |
[A further case of malignant hyperpyrexia and its treatment with lidocaine, methylprednisolone and verapamil (iproveratril) (author's transl)].
Topics: Acidosis; Adult; Calcium; Cryotherapy; Glucose; Halothane; Humans; Insulin; Lidocaine; Male; Maligna | 1976 |
Dantrolene in porcine malignant hyperthermia.
Topics: Animals; Dantrolene; Halothane; Hydantoins; Malignant Hyperthermia; Succinylcholine; Swine | 1976 |
Porcine malignant hyperthermia. I: Metabolic and physiological changes.
Topics: Animals; Blood Glucose; Body Temperature; Carbon Dioxide; Cardiac Output; Catecholamines; Fatty Acid | 1976 |
Porcine malignant hyperthermia. II: Heat production.
Topics: Animals; Body Temperature Regulation; Glucose; Halothane; Malignant Hyperthermia; Muscles; Oxygen Co | 1976 |
Halothane effects on human malignant hyperthermia skeletal muscle single calcium-release channels in planar lipid bilayers.
Topics: Calcium Channels; Disease Susceptibility; Electric Stimulation; Halothane; Humans; Lipid Bilayers; M | 1992 |
An EPR investigation of spin-labelled erythrocytes as a diagnostic technique for malignant hyperthermia.
Topics: Benzyl Alcohol; Benzyl Alcohols; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Halotha | 1992 |
Modulation of Ca2+ release and Na+ channel function in skeletal muscle by fatty acids.
Topics: Calcium; Cells, Cultured; Halothane; Humans; Isoproterenol; Linolenic Acids; Malignant Hyperthermia; | 1992 |
Evaluation of spin resonance spectroscopy of red blood cell membranes to detect malignant hyperthermia susceptibility.
Topics: Disease Susceptibility; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Halothane; Human | 1992 |
W-7, a calmodulin antagonist, and contracture of malignant hyperthermia susceptible skeletal muscle.
Topics: Animals; Caffeine; Calcium; Calmodulin; Dantrolene; Drug Synergism; Halothane; Intercellular Signali | 1992 |
Multiple restriction fragment length polymorphisms in the porcine calcium release channel gene (CRC): assignment to the halothane (HAL) linkage group.
Topics: Animals; Blotting, Southern; Calcium Channels; DNA Probes; Genetic Linkage; Genetic Markers; Halotha | 1992 |
Effect of Bay K 8644 on the magnitude of isoflurane and halothane contracture of skeletal muscle from patients susceptible to malignant hyperthermia.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
Sources of variability in halothane and caffeine contracture tests for susceptibility to malignant hyperthermia.
Topics: Adolescent; Adult; Aged; Caffeine; Child; Contracture; Dose-Response Relationship, Drug; Female; Hal | 1992 |
Identification of halothane gene carriers by use of in vivo 31P nuclear magnetic resonance spectroscopy in pigs.
Topics: Animals; Breeding; Female; Genotype; Halothane; Heterozygote; Homozygote; Hydrogen-Ion Concentration | 1992 |
Atypical reactions to halothane in a subgroup of homozygous malignant hyperthermia(MH)-susceptible pigs: indication of a heterogenous genetic basis for the porcine syndrome.
Topics: Animals; Female; Genetic Predisposition to Disease; Halothane; Homozygote; Male; Malignant Hyperther | 1992 |
Increase of serotonin in plasma during onset of halothane-induced malignant hyperthermia in pigs.
Topics: Animals; Body Temperature; Female; Halothane; Hemodynamics; Male; Malignant Hyperthermia; Serotonin; | 1992 |
Na(+)-Ca2+ exchange influences halothane and caffeine contractures of malignant hyperthermic skeletal muscle.
Topics: Animals; Caffeine; Calcium; Carrier Proteins; Culture Media; Halothane; Kinetics; Malignant Hyperthe | 1992 |
Evaluation of greyhound susceptibility to malignant hyperthermia using halothane-succinylcholine anesthesia and caffeine-halothane muscle contractures.
Topics: Anesthesia, Inhalation; Animals; Caffeine; Disease Susceptibility; Dog Diseases; Dogs; Genetic Predi | 1992 |
Malignant hyperthermia susceptibility in patients with Duchenne's muscular dystrophy.
Topics: Adolescent; Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Child; Child, Preschool; Disease | 1992 |
Is the "K-type" caffeine-halothane responder susceptible to malignant hyperthermia?
Topics: Caffeine; Culture Techniques; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Mus | 1992 |
Educational computer simulation of malignant hyperthermia.
Topics: Adult; Body Temperature; Computer Simulation; Dantrolene; Education, Medical; Female; Halothane; Hum | 1992 |
Muscle rigidity following halothane anesthesia in two patients with Freeman-Sheldon syndrome.
Topics: Child, Preschool; Female; Halothane; Humans; Intraoperative Complications; Male; Malignant Hyperther | 1992 |
Propofol anaesthesia in malignant hyperpyrexia susceptible swine.
Topics: Anesthesia; Animals; Caffeine; Female; Halothane; Injections, Intravenous; Male; Malignant Hyperther | 1992 |
Effect of halothane equilibration kinetics on in vitro muscle contractures for malignant hyperthermia screening.
Topics: Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contr | 1992 |
31P NMR and freeze fracture studies of sarcoplasmic reticulum membranes from normal and malignant hyperthermic pigs: effect of halothane and dantrolene.
Topics: Animals; Dantrolene; Freeze Fracturing; Halothane; Magnetic Resonance Spectroscopy; Malignant Hypert | 1992 |
Abnormalities in the regulation of blood platelet free cytosolic calcium in malignant hyperthermia. I. Human platelets.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Platelet Disorders; Blood Platelets; Calcium; Chil | 1992 |
Abnormalities in the regulation of blood platelet free cytosolic calcium in malignant hyperthermia. II. Pig platelets.
Topics: Animals; Blood Platelets; Calcium; Cytosol; Female; Genotype; Halothane; Homeostasis; Malignant Hype | 1992 |
Precautions when using halothane.
Topics: Anesthesia, Inhalation; Animals; Body Temperature Regulation; Cats; Dogs; Halothane; Heart; Liver; M | 1992 |
In vivo muscle 31P nuclear magnetic resonance spectroscopy during treatment of halothane-sensitive and halothane-nonsensitive pigs.
Topics: Adenosine Triphosphate; Animals; Female; Halothane; Magnetic Resonance Spectroscopy; Malignant Hyper | 1992 |
Masseter spasm and malignant hyperthermia: a retrospective review of a hospital-based pediatric otolaryngology practice.
Topics: Anesthesia, General; Child; Family Health; Halothane; Humans; Incidence; Malignant Hyperthermia; Mas | 1992 |
Propofol is a 'safe' anaesthetic agent in malignant hyperthermia susceptible patients.
Topics: Adolescent; Adult; Anesthesia, Intravenous; Caffeine; Contracture; Disease Susceptibility; Halothane | 1992 |
[Effects of halothane, caffeine and ryanodine on the intracellular calcium store in blood mononuclear cells].
Topics: Animals; Caffeine; Calcium; Disease Susceptibility; Halothane; Humans; Leukocytes, Mononuclear; Mali | 1992 |
The effects of volatile anesthetics on calcium regulation by malignant hyperthermia-susceptible sarcoplasmic reticulum.
Topics: Animals; Calcium; Disease Susceptibility; Enflurane; Halothane; In Vitro Techniques; Isoflurane; Mal | 1992 |
Abnormal rapid Ca2+ release from sarcoplasmic reticulum of malignant hyperthermia susceptible pigs.
Topics: Adenosine Triphosphatases; Animals; Biological Transport; Caffeine; Calcium; Calcium Channels; Filtr | 1991 |
Interactions of fatty acids with the calcium release channel in malignant hyperthermia.
Topics: Animals; Caffeine; Calcium Channels; Fatty Acids; Halothane; Horses; Humans; Isoproterenol; Lipase; | 1991 |
Membrane properties of the sarcolemma and sarcoplasmic reticulum of pigs susceptible to malignant hyperthermia. Action of halothane.
Topics: Animals; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Halothane; Hot Temperature; H | 1991 |
Serum creatine kinase activity as a selection criterion for stress susceptibility after standardised stress in pigs.
Topics: Adrenocorticotropic Hormone; Anesthesia; Animals; Creatine Kinase; Female; Halothane; Isoenzymes; Ma | 1991 |
Effects of neuroleptic agents on rat skeletal muscle contracture in vitro.
Topics: Animals; Antipsychotic Agents; Diaphragm; Droperidol; Drug Synergism; Haloperidol; Halothane; In Vit | 1991 |
Evidence for related myopathies in exertional heat stroke and malignant hyperthermia.
Topics: Adult; Biopsy; Caffeine; Disease Susceptibility; Family Health; Female; Halothane; Heat Exhaustion; | 1991 |
Use of the calcium agonist BAY K 8644 for in vitro diagnosis of susceptibility to malignant hyperthermia.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Effects of calcium-free solution, calcium antagonists, and the calcium agonist BAY K 8644 on mechanical responses of skeletal muscle from patients susceptible to malignant hyperthermia.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
BAY K 8644 and nifedipine alter halothane but not caffeine contractures of malignant hyperthermic muscle fibers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
EU 4093 decreases intracellular [Ca2+] in skeletal muscle fibers from control and malignant hyperthermia-susceptible swine.
Topics: Animals; Calcium; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Imidazoles; M | 1992 |
Is resting membrane potential a possible indicator of viability of muscle bundles used in the in vitro caffeine contracture test?
Topics: Caffeine; Electric Stimulation; Halothane; Humans; Malignant Hyperthermia; Membrane Potentials; Musc | 1992 |
In vitro contracture tests in patients with various neuromuscular diseases.
Topics: Adolescent; Adult; Aged; Caffeine; Child; Child, Preschool; Disease Susceptibility; Drug Hypersensit | 1992 |
Mitochondrial nucleotide translocase from skeletal muscle of halothane sensitive pigs: an electrophoretic study.
Topics: Animals; Disease Models, Animal; Halothane; Isoelectric Point; Malignant Hyperthermia; Mitochondria, | 1991 |
Why does halothane relax cardiac muscle but contract malignant hyperthermic skeletal muscle?
Topics: Animals; Caffeine; Calcium; Depression, Chemical; Fura-2; Halothane; In Vitro Techniques; Male; Mali | 1991 |
A substitution of cysteine for arginine 614 in the ryanodine receptor is potentially causative of human malignant hyperthermia.
Topics: Adolescent; Amino Acid Sequence; Arginine; Base Sequence; Caffeine; Cloning, Molecular; Cysteine; Ex | 1991 |
[A new emphasis on the diagnosis of malignant hyperthermia using the in vitro contracture test?].
Topics: Adolescent; Adult; Caffeine; Child; Child, Preschool; Disease Susceptibility; Halothane; Humans; In | 1991 |
[Diagnosis of malignant hyperthermia. The platelet test versus the in vitro contracture test].
Topics: Blood Platelets; Caffeine; Child; Disease Susceptibility; Halothane; Humans; Male; Malignant Hyperth | 1991 |
Kinetic analysis of halothane induced Ca2+ release from isolated heavy sarcoplasmic reticulum.
Topics: Calcium; Halothane; Humans; In Vitro Techniques; Kinetics; Malignant Hyperthermia; Muscles; Receptor | 1991 |
[In vitro diagnosis of malignant hyperpyrexia syndrome].
Topics: Adult; Caffeine; Dantrolene; Female; Halothane; Hernia, Inguinal; Humans; In Vitro Techniques; Male; | 1991 |
In vitro contraction test for malignant hyperthermia in patients with unexplained recurrent rhabdomyolysis.
Topics: Adult; Caffeine; Calcium; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hyperth | 1991 |
The effect of azumolene on hypercontractility and sarcoplasmic reticulum Ca(2+)-dependent ATPase activity of malignant hyperpyrexia-susceptible porcine skeletal muscle.
Topics: Animals; Caffeine; Calcium-Transporting ATPases; Dantrolene; Halothane; Imidazoles; Malignant Hypert | 1991 |
In vitro contracture testing for determination of susceptibility to malignant hyperthermia: a methodologic update.
Topics: Caffeine; Chromatography, Gas; Contracture; Diffusion Chambers, Culture; Disease Susceptibility; Ele | 1991 |
Pharmacogenetics of caffeine and caffeine-halothane contractures in biopsies of human skeletal muscle.
Topics: Adolescent; Adult; Aged; Aging; Caffeine; Child; Child, Preschool; Female; Genetic Variation; Haloth | 1991 |
Evidence for intraluminal Ca++ regulatory site defect in sarcoplasmic reticulum from malignant hyperthermia pig muscle.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Diphosphates; Halothane; Malignant Hyperthermia; Mus | 1991 |
Effects of caffeine, halothane, succinylcholine, phenylephrine and isoproterenol on myocardial force of contraction of malignant hyperthermia susceptible swine.
Topics: Animals; Caffeine; Disease Susceptibility; Halothane; Isoproterenol; Malignant Hyperthermia; Myocard | 1991 |
Characterization of swine susceptible to malignant hyperthermia by in vivo, in vitro and post-mortem techniques.
Topics: Administration, Inhalation; Animals; Caffeine; Creatine Kinase; Disease Susceptibility; Genotype; Ha | 1991 |
[Malignant hyperthermia: halothane kinetics in a study model of muscular contraction. Head space determination and comparison with a mathematical model].
Topics: Chromatography; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hypertherm | 1991 |
Malignant hyperthermia: normal muscle calcium uptake and abnormal caffeine and halothane contractures.
Topics: Adult; Biopsy; Caffeine; Calcium; Disease Susceptibility; False Negative Reactions; Female; Halothan | 1991 |
Comparison of North American and European malignant hyperthermia group halothane contracture testing protocols in swine.
Topics: Animals; Disease Susceptibility; Europe; Halothane; Malignant Hyperthermia; Muscle Contraction; Nort | 1991 |
Masseter muscle spasm in children: implications of continuing the triggering anesthetic.
Topics: Anesthesia, Inhalation; Arrhythmias, Cardiac; Carbon Dioxide; Child; Child, Preschool; Creatine Kina | 1991 |
Fatty acids markedly lower the threshold for halothane-induced calcium release from the terminal cisternae in human and porcine normal and malignant hyperthermia susceptible skeletal muscle.
Topics: Animals; Calcium; Fatty Acids; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscl | 1991 |
[Cardiac arrest during anesthesia induction with halothane and succinylcholine in an infant. Massive hyperkalemia and rhabdomyolysis in suspected myopathy and/or malignant hyperthermia].
Topics: Anesthesia, Inhalation; Cardiomyopathies; Halothane; Heart Arrest; Humans; Hyperkalemia; Infant; Mal | 1991 |
Ryanodine receptor gene is a candidate for predisposition to malignant hyperthermia.
Topics: Animals; Caffeine; Chromosomes, Human, Pair 19; Female; Genetic Linkage; Halothane; Heterozygote; Ho | 1990 |
The porcine PHIcDNA linked to the halothane gene detects a NotI RFLP in normal and malignant hyperthermia susceptible pigs.
Topics: Animals; Deoxyribonucleases, Type II Site-Specific; Genes; Genetic Linkage; Genetic Predisposition t | 1990 |
The porcine PHIcDNA linked to the halothane gene detects a HindIII and XbaI RFLP in normal and malignant hyperthermia susceptible pigs.
Topics: Animals; Deoxyribonuclease HindIII; Deoxyribonucleases, Type II Site-Specific; Genes; Genetic Linkag | 1990 |
Enhanced mobilization of intracellular Ca2+ induced by halothane in hepatocytes isolated from swine susceptible to malignant hyperthermia.
Topics: Animals; Calcium; Disease Susceptibility; Halothane; In Vitro Techniques; Ions; Liver; Malignant Hyp | 1991 |
Calcium handling by platelets from normal and malignant hyperthermia-susceptible pigs.
Topics: Animals; Biological Transport; Blood Platelets; Caffeine; Calcium; Halothane; Malignant Hyperthermia | 1991 |
Malignant hyperthermia in dogs.
Topics: Animals; Biopsy; Caffeine; Crosses, Genetic; Dantrolene; Dog Diseases; Dogs; Female; Halothane; Hear | 1991 |
[Diagnosis of susceptibility for malignant hyperthermia using in-vitro muscle contraction testing in Switzerland].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biopsy; Caffeine; Child; Female; Genetic Predisposition | 1991 |
Molecular genetics and malignant hyperthermia.
Topics: Caffeine; Genetic Markers; Halothane; Humans; Malignant Hyperthermia; Molecular Biology | 1991 |
A comparison of the caffeine halothane muscle contracture test with the molecular genetic diagnosis of malignant hyperthermia.
Topics: Alleles; Caffeine; Child; Female; Genetic Linkage; Genetic Markers; Halothane; Humans; Male; Maligna | 1991 |
Halothane-dependent release of intracellular Ca2+ in blood cells in malignant hyperthermia.
Topics: Animals; Caffeine; Calcium; Cytosol; Disease Susceptibility; Egtazic Acid; Halothane; Humans; Malign | 1990 |
Fatty acids modulate calcium-induced calcium release from skeletal muscle heavy sarcoplasmic reticulum fractions: implications for malignant hyperthermia.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Chromatography, Gas; Fatty Acids; Halothane; | 1990 |
Uptake and release of calcium ions by heavy sarcoplasmic reticulum fraction of normal and malignant hyperthermia-susceptible human skeletal muscle.
Topics: Azides; Biological Transport, Active; Calcium; Calcium-Transporting ATPases; Dantrolene; Halothane; | 1990 |
[Do neuroleptic malignant syndrome and malignant hyperthermia of anesthesia share a common mechanism?].
Topics: Caffeine; Halothane; Humans; Malignant Hyperthermia; Neuroleptic Malignant Syndrome | 1990 |
Microassay for malignant hyperthermia susceptibility: hypersensitive ligand-gating of the Ca channel in muscle sarcoplasmic reticulum causes increased amounts and rates of Ca-release.
Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Channels; Halothane; Ion Channel Gating; | 1990 |
Abnormal fluidity state in membranes of malignant hyperthermia pig skeletal muscle.
Topics: Animals; Electron Spin Resonance Spectroscopy; Fluorescence Polarization; Halothane; Malignant Hyper | 1990 |
The importance of calcium ions for in vitro malignant hyperthermia testing.
Topics: Caffeine; Calcium; Contracture; Drug Interactions; Halothane; Humans; In Vitro Techniques; Malignant | 1990 |
Inappropriate use of the t-test.
Topics: Animals; Caffeine; Halothane; Malignant Hyperthermia; Statistics as Topic; Swine | 1990 |
Alterations in brain electrical activity may indicate the onset of malignant hyperthermia in swine.
Topics: Anesthesia, Inhalation; Animals; Brain; Disease Susceptibility; Electroencephalography; Halothane; M | 1990 |
Are myotonias and periodic paralyses associated with susceptibility to malignant hyperthermia?
Topics: Biopsy; Caffeine; Calcium; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant | 1990 |
Prediction of the halothane (Hal) genotypes by means of linked marker loci (Phi, Po2, Pgd) in Quebec Landrace pigs.
Topics: Alleles; Animals; Gene Frequency; Genetic Linkage; Genetic Markers; Halothane; Haplotypes; Incidence | 1990 |
Importance of fasting in the lymphocyte calcium test for malignant hyperthermia.
Topics: Adolescent; Adult; Aged; Caffeine; Calcium; Contracture; Cytoplasm; Fasting; Female; Halothane; Huma | 1990 |
Influence of salbutamol on the in vitro muscle response to caffeine and halothane in malignant hyperthermia.
Topics: Adult; Albuterol; Caffeine; Contracture; Dose-Response Relationship, Drug; Drug Interactions; Female | 1990 |
Caffeine and halothane contracture testing in swine using the recommendations of the North American Malignant Hyperthermia Group.
Topics: Animals; Caffeine; Disease Susceptibility; Halothane; In Vitro Techniques; Malignant Hyperthermia; M | 1990 |
Localization of the malignant hyperthermia susceptibility locus to human chromosome 19q12-13.2.
Topics: Animals; Caffeine; Chromosome Mapping; Chromosomes, Human, Pair 19; Female; Genetic Linkage; Halotha | 1990 |
Canine stress syndrome/malignant hyperthermia susceptibility: calcium-homeostasis defect in muscle and lymphocytes.
Topics: Animals; Calcium; Cytosol; Dog Diseases; Dogs; Female; Halothane; Homeostasis; Lymphocytes; Malignan | 1990 |
Clinical concentrations of verapamil affect the in vitro diagnosis of susceptibility to malignant hyperpyrexia.
Topics: Caffeine; Disease Susceptibility; False Negative Reactions; Halothane; Humans; In Vitro Techniques; | 1990 |
Azumolene reverses episodes of malignant hyperthermia in susceptible swine.
Topics: Animals; Halothane; Imidazoles; Injections, Intravenous; Malignant Hyperthermia; Muscle Relaxants, C | 1990 |
Safety of general anesthesia in patients previously tested negative for malignant hyperthermia susceptibility.
Topics: Anesthesia, General; Caffeine; Contracture; Disease Susceptibility; Halothane; Humans; Malignant Hyp | 1990 |
Malignant hyperthermia in the otolaryngologic patient: prospective anesthetic and surgical management of eight children.
Topics: Adenoidectomy; Anesthesia, General; Anxiety; Caffeine; Child; Child, Preschool; Contracture; Female; | 1990 |
An association between certain congenital abnormalities and the malignant hyperthermia trait.
Topics: Adolescent; Adult; Caffeine; Child; Child, Preschool; Congenital Abnormalities; Female; Halothane; H | 1990 |
The effects of extracellular magnesium on myoplasmic [Ca2+] in malignant hyperthermia susceptible swine.
Topics: Animals; Calcium; Dantrolene; Disease Susceptibility; Extracellular Space; Halothane; Magnesium Sulf | 1990 |
Erythrocyte osmotic fragility, serum creatine kinase and its isoenzymes related to body weight in porcine malignant hyperthermia.
Topics: Animals; Body Weight; Creatine Kinase; Halothane; Hemolysis; Isoenzymes; Malignant Hyperthermia; Osm | 1990 |
Current diagnostic methods of malignant hyperthermia: an evaluation.
Topics: Caffeine; Chromosomes, Human, Pair 19; Disease Susceptibility; Halothane; Humans; Magnetic Resonance | 1990 |
Diltiazem and nifedipine reduce the in vitro contracture response to halothane in malignant hyperthermia-susceptible muscle.
Topics: Depression, Chemical; Diltiazem; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Mal | 1990 |
Halothane sensitivity of young pigs in vivo and in vitro.
Topics: Animals; Drug Hypersensitivity; Halothane; Malignant Hyperthermia; Muscle Contraction; Muscles; Succ | 1990 |
Efficiency of selection strategies for halothane-negative gene.
Topics: Alleles; Animals; Gene Frequency; Genotype; Halothane; Male; Malignant Hyperthermia; Phenotype; Prob | 1990 |
Effects of the calcium antagonist, TMB-8 on halothane and on caffeine contractures of malignant hyperthermia susceptible skeletal muscle.
Topics: Animals; Caffeine; Calcium Channel Blockers; Gallic Acid; Halothane; In Vitro Techniques; Malignant | 1990 |
Compensatory increase in calcium extrusion activity of untreated lymphocytes from swine susceptible to malignant hyperthermia.
Topics: Animals; Caffeine; Calcium; Disease Susceptibility; Halothane; Lymphocytes; Malignant Hyperthermia; | 1990 |
Porcine malignant hyperthermia: critical temperatures for in vivo and in vitro responses.
Topics: Animals; Body Temperature; Calcium; Disease Susceptibility; Halothane; In Vitro Techniques; Malignan | 1990 |
Abnormal membrane properties of the sarcoplasmic reticulum of pigs susceptible to malignant hyperthermia: modes of action of halothane, caffeine, dantrolene, and two other drugs.
Topics: Animals; Caffeine; Calcium; Dantrolene; Electron Spin Resonance Spectroscopy; Halothane; Intracellul | 1986 |
Effects of halothane, caffeine, dantrolene and tetracaine on the calcium permeability of skeletal sarcoplasmic reticulum of malignant hyperthermic pigs.
Topics: Animals; Caffeine; Calcium; Cell Membrane Permeability; Dantrolene; Halothane; Kinetics; Malignant H | 1987 |
No relationship between fiber type and halothane contracture test results in malignant hyperthermia.
Topics: Adenosine Triphosphatases; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Muscles; S | 1987 |
[Effects of BAY K 8644, a slow calcium channel agonist, on muscle contraction induced by halothane in sensitive subjects with malignant hyperthermia].
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
Erythrocyte osmotic fragility in porcine malignant hyperthermia and effects of halothane.
Topics: Animals; Halothane; Malignant Hyperthermia; Osmotic Fragility; Swine; Swine Diseases | 1989 |
[Central core disease associated with malignant hyperthermia sensitivity].
Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Child; Child, Preschool; Creatine Kinase; Female; Halotha | 1989 |
Malignant hyperthermia: slow sodium current in cultured human muscle cells.
Topics: Caffeine; Cells, Cultured; Disease Susceptibility; Electric Conductivity; Halothane; Humans; Maligna | 1989 |
Inositol 1,4,5-trisphosphate phosphatase deficiency and malignant hyperpyrexia in swine.
Topics: Animals; Calcium; Halothane; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Malignant Hypertherm | 1989 |
The association between the neuroleptic malignant syndrome and malignant hyperthermia.
Topics: Adult; Caffeine; Chlorpromazine; Contracture; Disease Susceptibility; Female; Halothane; Humans; Mal | 1989 |
Preparation of theatres for malignant hyperpyrexia patients.
Topics: Anesthesia, General; Gas Scavengers; Halothane; Humans; Malignant Hyperthermia; Operating Rooms; Ven | 1989 |
Effect of diltiazem, verapamil and dantrolene on the contractility of isolated malignant hyperpyrexia-susceptible human skeletal muscle.
Topics: Caffeine; Dantrolene; Diltiazem; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Mal | 1989 |
[The action of ketamine on muscle contractile behavior. In vitro studies on the musculature of subjects susceptible to malignant hyperthermia].
Topics: Caffeine; Disease Susceptibility; Halothane; In Vitro Techniques; Ketamine; Malignant Hyperthermia; | 1989 |
Activities of some serum enzymes in halothane reacted and non-reacted pigs.
Topics: Animals; Halothane; Malignant Hyperthermia; Muscles; Swine; Swine Diseases | 1989 |
Possible malignant hyperthermia in a 7-week-old infant.
Topics: Creatine Kinase; Halothane; Humans; Infant; Male; Malignant Hyperthermia; Muscular Dystrophies; Succ | 1989 |
[Malignant hyperthermia; two cases of MH in the presence of general anesthesia and performing caffeine contracture test].
Topics: Adult; Caffeine; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscle Contra | 1989 |
Malignant hyperthermia: effects of halothane on the surface membrane.
Topics: Action Potentials; Animals; Dantrolene; Halothane; Malignant Hyperthermia; Membrane Potentials; Musc | 1989 |
The in vitro determination of susceptibility to malignant hyperthermia.
Topics: Animals; Caffeine; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Swine | 1989 |
31P-NMR spectroscopy: the metabolic profile of malignant hyperpyrexic porcine skeletal muscle.
Topics: Animals; Caffeine; Halothane; Magnetic Resonance Imaging; Malignant Hyperthermia; Muscles; Phosphoru | 1989 |
Effects of droperidol, haloperidol and ketamine on halothane, succinylcholine and caffeine contractures: implications for malignant hyperthermia.
Topics: Animals; Caffeine; Contracture; Droperidol; Haloperidol; Halothane; Humans; Ketamine; Male; Malignan | 1989 |
Effect of diltiazem and dantrolene on the contractility of isolated malignant hyperpyrexia-susceptible porcine skeletal muscle.
Topics: Animals; Caffeine; Dantrolene; Diltiazem; Dose-Response Relationship, Drug; Halothane; In Vitro Tech | 1989 |
Effect of diltiazem on porcine malignant hyperpyrexia induced by suxamethonium and halothane.
Topics: Anesthesia; Animals; Blood Pressure; Diltiazem; Female; Halothane; Male; Malignant Hyperthermia; Suc | 1989 |
Porcine malignant hyperthermia: halothane effects on force generation in skeletal muscles.
Topics: Animals; Calcium; Electric Stimulation; Halothane; Malignant Hyperthermia; Muscle Contraction; Muscl | 1989 |
Sensitivity of the adenine nucleotide metabolism of platelets from malignant hyperthermia patients to halothane.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adolesc | 1989 |
Standards for halothane/caffeine contracture test.
Topics: Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction | 1989 |
Malignant hyperthermia in humans--standardization of contracture testing protocol.
Topics: Biopsy; Caffeine; Clinical Laboratory Techniques; Drug Combinations; Halothane; Humans; Malignant Hy | 1989 |
Fluoxetine treatment of a depressed patient susceptible to malignant hyperthermia.
Topics: Adolescent; Caffeine; Depressive Disorder; Disease Susceptibility; Female; Fluoxetine; Halothane; Hu | 1989 |
The screening of propofol in MHS swine.
Topics: Anesthetics; Animals; Halothane; Malignant Hyperthermia; Phenols; Propofol; Swine | 1989 |
Malignant hyperthermia and the clean machine.
Topics: Air Pollutants; Anesthesia, Inhalation; Equipment Contamination; Halothane; Humans; Malignant Hypert | 1989 |
[Halothane anesthesia of several hours' duration in swine of the German Landrace breed, selected for resistance to malignant hyperthermia].
Topics: Anesthesia; Animals; Breeding; Female; Halothane; Homozygote; Malignant Hyperthermia; Swine; Swine D | 1989 |
Influence of propranolol on the in vitro response to caffeine and halothane in malignant hyperthermia-susceptible muscle.
Topics: Anesthesia; Caffeine; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Interactions; H | 1989 |
Halothane-sensitivity gene and muscle contractile properties in malignant hyperthermia.
Topics: Animals; Genes; Genetic Carrier Screening; Halothane; Homozygote; Malignant Hyperthermia; Muscle Con | 1989 |
Effects of the halothane-sensitivity gene on sarcoplasmic reticulum function.
Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Genes; Halothane; Kinetics; Malignant Hypertherm | 1989 |
[Diagnosis of susceptibility to malignant hyperthermia using the in vitro contracture test].
Topics: Adolescent; Adult; Aged; Anesthesia; Electromyography; Female; Halothane; Humans; In Vitro Technique | 1987 |
Differential effects of halothane on adult and juvenile sodium channels in human muscle.
Topics: Action Potentials; Calcium; Halothane; Humans; Malignant Hyperthermia; Muscles; Sodium Channels; Tim | 1988 |
Halothane induced disorder of red cell membranes of subjects susceptible to malignant hyperthermia.
Topics: Animals; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Halothane; Humans; Malignant Hy | 1988 |
Detection of malignant hyperthermia susceptibility using a spin label technique on red blood cells.
Topics: Cyclic N-Oxides; Disease Susceptibility; Electron Spin Resonance Spectroscopy; Erythrocytes; Halotha | 1988 |
Vecuronium and porcine malignant hyperthermia.
Topics: Anesthesia, General; Animals; Body Temperature; Carbon Dioxide; Halothane; Heart Rate; Malignant Hyp | 1985 |
Anaesthetic-induced increase in ionised calcium in blood mononuclear cells from malignant hyperthermia patients.
Topics: Aminoquinolines; Anesthetics; Caffeine; Calcium; Drug Evaluation; Halothane; Humans; In Vitro Techni | 1987 |
Ca-induced Ca release in malignant hyperthermia-susceptible pig skeletal muscle.
Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Halothane; In Vitro Techniques; Kinetics; Malign | 1989 |
Porcine malignant hyperthermia susceptibility: halothane-induced increase in cytoplasmic free calcium in lymphocytes.
Topics: Animals; Calcium; Cytosol; Disease Susceptibility; Halothane; Lymphocytes; Malignant Hyperthermia; S | 1989 |
Ketanserin and malignant hyperthermia in pigs.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Temperature; Carbon Dioxide; Halothane; Heart | 1986 |
[Malignant hyperthermia following halothane anesthesia for more than 3 hours].
Topics: Anesthesia, General; Child; Halothane; Humans; Male; Malignant Hyperthermia; Syndactyly; Time Factor | 1986 |
[Contracture test with ionophore A 23187 for the diagnosis of malignant hyperthermia].
Topics: Adolescent; Adult; Caffeine; Calcimycin; Contracture; Female; Halothane; Humans; Male; Malignant Hyp | 1986 |
Treatment of porcine malignant hyperthermia: lactate gradient from muscle to blood.
Topics: Animals; Bicarbonates; Carbon Dioxide; Dantrolene; Halothane; Lactates; Lactic Acid; Malignant Hyper | 1986 |
Effects of Sarcocystis miescheriana infection on carcass quality and on the water-binding capacity of the meat of halothane-tested fattening pigs.
Topics: Absorption; Animals; Body Composition; Halothane; Malignant Hyperthermia; Meat; Sarcocystosis; Swine | 1988 |
The effects of Sarcocystis miescheriana infections on blood enzymes and weight gain of stress-sensitive and stress-insensitive pigs.
Topics: Animals; Antibodies, Protozoan; Aspartate Aminotransferases; Body Weight; Creatine Kinase; Halothane | 1988 |
[Contractile responses of the renal and iliac arteries to catecholamines in the presence of halothane in swine susceptible to malignant hyperthermia].
Topics: Animals; Catecholamines; Halothane; Iliac Artery; Malignant Hyperthermia; Renal Artery; Swine; Swine | 1988 |
Preparation of anesthesia machines for patients susceptible to malignant hyperthermia.
Topics: Anesthesia, Inhalation; Anesthesiology; Chromatography, Gas; Disease Susceptibility; Equipment Conta | 1988 |
Open canalicular system of platelets in porcine stress syndrome.
Topics: Animals; Blood Platelets; Halothane; Malignant Hyperthermia; Microscopy, Electron; Stress, Physiolog | 1988 |
Malignant hyperthermia in plastic surgery.
Topics: Adult; Caffeine; Child; Child, Preschool; Dermoid Cyst; Disease Susceptibility; Facial Neoplasms; Fe | 1988 |
Halothane induced vasomotion of coronary, renal and iliac arterial rings in malignant hyperthermia susceptible swine.
Topics: Animals; Coronary Vessels; Culture Techniques; Halothane; Iliac Artery; Malignant Hyperthermia; Musc | 1988 |
Porcine malignant hyperthermia carrier detection and chromosomal assignment using a linked probe.
Topics: Animals; Chromosome Mapping; DNA Probes; Drug Resistance; Female; Genetic Carrier Screening; Genetic | 1988 |
Effects of halothane on the mechanical responses in vitro of coronary arterial rings of malignant hyperthermia susceptible swine.
Topics: Animals; Coronary Vessels; Epinephrine; Halothane; In Vitro Techniques; Malignant Hyperthermia; Musc | 1988 |
Calmodulin-antagonist drugs and porcine malignant hyperpyrexia.
Topics: Animals; Caffeine; Calmodulin; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contra | 1988 |
Re: Anesthetic induction trismus, more than a closed mouth problem.
Topics: Anesthesia, Inhalation; Child, Preschool; Emergency Medical Tags; Halothane; Humans; Male; Malignant | 1988 |
Myoplasmic free [Ca2+] during a malignant hyperthermia episode in swine.
Topics: Animals; Calcium; Dantrolene; Halothane; Malignant Hyperthermia; Membrane Potentials; Muscles; Osmol | 1988 |
Age, fiber type composition and in vitro contracture responses in human malignant hyperthermia.
Topics: Adolescent; Adult; Aging; Caffeine; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; | 1988 |
Malignant hyperthermia in myotonia congenita.
Topics: Adult; Anesthesia; Biopsy; Female; Halothane; Humans; Malignant Hyperthermia; Muscles; Myotonia Cong | 1988 |
[Tests of contracture and sensitivity to malignant hyperthermia in 27 patients].
Topics: Adolescent; Adult; Anesthesia, General; Biopsy; Caffeine; Child; Child, Preschool; Contracture; Crea | 1988 |
Halothane-caffeine contracture testing in neuromuscular diseases.
Topics: Biopsy; Caffeine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction; Muscles; Neuromuscu | 1988 |
Plasma pyruvate kinase activity vs creatine kinase activity as an indicator of the porcine stress syndrome.
Topics: Animals; Clinical Enzyme Tests; Creatine Kinase; Disease Susceptibility; Female; Halothane; Male; Ma | 1988 |
The effects of calcium channel blocking drugs on halothane initiation of malignant hyperthermia in MHS swine and on the established syndrome.
Topics: Anesthesia, General; Animals; Calcium Channel Blockers; Diltiazem; Flunarizine; Halothane; Malignant | 1988 |
Fura-2 detected myoplasmic calcium and its correlation with contracture force in skeletal muscle from normal and malignant hyperthermia susceptible pigs.
Topics: Animals; Benzofurans; Caffeine; Calcium; Disease Susceptibility; Fura-2; Halothane; Malignant Hypert | 1988 |
Malignant hyperthermia in a patient with King syndrome.
Topics: Child, Preschool; Halothane; Humans; Male; Malignant Hyperthermia; Syndrome | 1988 |
[Malignant hyperthermia in Austria. II. A comparison of the results of diagnostic test procedures].
Topics: Adult; Caffeine; Creatine Kinase; Disease Susceptibility; Electromyography; Female; Halothane; Human | 1988 |
Neuroleptic malignant syndrome and malignant hyperthermia. In vitro comparison with halothane and caffeine contracture tests.
Topics: Adult; Aged; Caffeine; Disease Susceptibility; Female; Halothane; Humans; In Vitro Techniques; Male; | 1987 |
Anaesthesia for patients with arthrogryposis multiplex congenita: what is the risk of malignant hyperthermia?
Topics: Anesthetics; Arthrogryposis; Child; Female; Halothane; Humans; Male; Malignant Hyperthermia; Risk | 1986 |
Prediction of malignant hyperthermia susceptibility by clinical signs.
Topics: Adolescent; Anesthesia, General; Biopsy; Caffeine; Child; Halothane; Humans; Infant; Malignant Hyper | 1987 |
Porcine malignant hyperthermia: false negatives in the halothane test.
Topics: Animals; Disease Susceptibility; False Negative Reactions; Genotype; Halothane; Malignant Hypertherm | 1987 |
Abnormal relaxation rates in subjects susceptible to malignant hyperthermia.
Topics: Adolescent; Adult; Caffeine; Electromyography; Female; Halothane; Humans; Male; Malignant Hypertherm | 1987 |
Selective increase in cytoplasmic calcium by anesthetic in lymphocytes from malignant hyperthermia-susceptible pigs.
Topics: Aminoquinolines; Animals; Calcium; Cytoplasm; Fluorescent Dyes; Halothane; Lymphocytes; Malignant Hy | 1987 |
Calcium uptake in frozen muscle biopsy sections compared with other predictors of malignant hyperthermia susceptibility.
Topics: Animals; Biopsy; Caffeine; Calcium; Cats; Female; Halothane; Humans; Male; Malignant Hyperthermia; M | 1987 |
Malignant hyperthermia susceptibility in neuroleptic malignant syndrome.
Topics: Adult; Disease Susceptibility; Female; Fluphenazine; Halothane; Humans; Male; Malignant Hyperthermia | 1987 |
Effects of anaesthetic agents on erythrocyte fragility: comparison of normal and malignant hyperthermia susceptible patients.
Topics: Disease Susceptibility; Ethanol; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Osm | 1987 |
In vitro diagnosis of susceptibility to malignant hyperthermia: evaluation of tests with halothane-caffeine, potassium chloride, suxamethonium and caffeine-suxamethonium.
Topics: Caffeine; Disease Susceptibility; Evaluation Studies as Topic; Halothane; Humans; In Vitro Technique | 1987 |
In vitro diagnosis of susceptibility to malignant hyperthermia: comparison between dynamic and static halothane and caffeine tests.
Topics: Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Mu | 1987 |
Erythrocyte fragility screening is not a tool for diagnosis of human malignant hyperthermia.
Topics: Biopsy; Erythrocytes; Halothane; Humans; Malignant Hyperthermia; Muscles; Osmotic Fragility | 1987 |
Malignant hyperthermia in a three-month-old American Indian infant.
Topics: Age Factors; Atracurium; Female; Halothane; Humans; Indians, North American; Infant; Malignant Hyper | 1987 |
[Changes in the content of membrane phospholipids of subcellular structures of skeletal muscle in halothane-induced malignant hyperthermia of the domestic pig].
Topics: Animals; Halothane; Intracellular Membranes; Malignant Hyperthermia; Membrane Lipids; Muscles; Phosp | 1987 |
Halothane-cooling contractures of mammalian muscles.
Topics: Anesthetics, Local; Animals; Caffeine; Calcium; Cold Temperature; Dantrolene; Dose-Response Relation | 1986 |
Static v. dynamic tests in the in vitro diagnosis of malignant hyperthermia susceptibility.
Topics: Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Male; Malignant Hypertherm | 1986 |
[Contracture response to isoflurane and pentazocine in muscles of a patient with malignant hyperthermia].
Topics: Caffeine; Child; Halothane; Humans; In Vitro Techniques; Isoflurane; Male; Malignant Hyperthermia; M | 1986 |
[Malignant hyperthermia in a 41-year-old woman].
Topics: Adult; Anesthesia; Arrhythmias, Cardiac; Female; Halothane; Humans; Malignant Hyperthermia | 1986 |
[Carpopedal spasm during anesthesia with halothane: malignant hyperthermia or tetany?].
Topics: Anesthesia, Inhalation; Child, Preschool; Diagnosis, Differential; Halothane; Humans; Male; Malignan | 1986 |
Malignant hyperthermia: clinical course and metabolic changes in two patients.
Topics: Catecholamines; Child; Child, Preschool; Dantrolene; Female; Halothane; Humans; Hydrocortisone; Mali | 1986 |
Duchenne muscular dystrophy and malignant hyperthermia--two case reports.
Topics: Anesthesia, Inhalation; Child, Preschool; Fentanyl; Halothane; Humans; Hyperkalemia; Infant; Male; M | 1986 |
Porcine malignant hyperthermia susceptibility: hypersensitive calcium-release mechanism of skeletal muscle sarcoplasmic reticulum.
Topics: Animals; Biopsy; Calcium; Genes, Dominant; Halothane; Malignant Hyperthermia; Muscles; Sarcoplasmic | 1986 |
The screening of atracurium in MHS swine.
Topics: Animals; Atracurium; Creatine Kinase; Drug Evaluation, Preclinical; Halothane; Isoquinolines; Malign | 1986 |
[Examination of the family of a patient susceptible to anesthetic malignant hyperthermia].
Topics: Adolescent; Adult; Biopsy; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hypert | 1986 |
In vitro muscle contractures induced by halothane and suxamethonium. II: Human skeletal muscle from normal and malignant hyperthermia susceptible patients.
Topics: Disease Susceptibility; Fatty Acids, Nonesterified; Halothane; Humans; In Vitro Techniques; Indometh | 1986 |
Evaluation of a commercial creatine kinase screening test for malignant hyperthermia (porcine stress syndrome).
Topics: Age Factors; Analysis of Variance; Animals; Clinical Enzyme Tests; Creatine Kinase; Halothane; Lumin | 1986 |
Investigation of malignant hyperthermia in Sweden.
Topics: Adolescent; Adult; Aged; Caffeine; Child; Female; Halothane; Humans; Male; Malignant Hyperthermia; M | 1986 |
[Postoperative hyperthermic syndrome with a questionable relationship to malignant hyperthermia and the need for elucidating susceptibility].
Topics: Anesthesia; Female; Halothane; Humans; Malignant Hyperthermia; Middle Aged; Postoperative Complicati | 1986 |
[Detection of peranesthetic malignant hyperthermia by muscle contracture tests and NMR spectroscopy].
Topics: Biopsy; Caffeine; Halothane; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Malignant | 1986 |
Changes in cytoplasmic free calcium caused by halothane. Role of the plasma membrane and intracellular Ca2+ stores.
Topics: Aminoquinolines; Animals; Calcium; Cell Membrane; Cytoplasm; Halothane; Humans; Kinetics; Lymphocyte | 1986 |
Prediction of the halothane (Hal) genotypes of pigs by deducing Hal, Phi, Po2, Pgd haplotypes of parents and offspring: results from a large-scale practice in Swedish breeds.
Topics: Alleles; Animals; Blood Proteins; Crosses, Genetic; Erythrocytes; Female; Genetic Linkage; Genotype; | 1985 |
[Muscle fibers of pigs sensitive to halothane and resistant to it].
Topics: Animals; Halothane; Histocytochemistry; Malignant Hyperthermia; Muscles; Swine; Swine Diseases | 1985 |
Diagnosis of malignant hyperthermia: implications for the military.
Topics: Adolescent; Adult; Caffeine; Halothane; Humans; Male; Malignant Hyperthermia; Military Medicine; Mus | 1985 |
Malignant hyperthermia.
Topics: Adult; Anesthesia; Animals; Caffeine; Child; Creatine Kinase; Disease Susceptibility; Halothane; Hum | 1985 |
[Capnography and anesthetic-induced malignant hyperthermia].
Topics: Animals; Carbon Dioxide; Dantrolene; Halothane; Malignant Hyperthermia; Monitoring, Physiologic; Suc | 1985 |
Neuroleptic malignant syndrome and use of anesthetic agents.
Topics: Anesthetics; Halothane; Humans; Malignant Hyperthermia; Neuroleptic Malignant Syndrome; Succinylchol | 1986 |
Masseter muscle rigidity and malignant hyperthermia susceptibility.
Topics: Caffeine; Child; Creatine Kinase; Female; Halothane; Humans; Male; Malignant Hyperthermia; Masseter | 1986 |
Failure of the platelet-halothane nucleotide depletion test as a diagnostic or screening test for malignant hyperthermia.
Topics: Blood Platelets; Caffeine; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Co | 1986 |
The temperature dependence of halothane-induced contractures of skeletal muscle.
Topics: Anesthetics, Local; Animals; Anura; Caffeine; Calcium; Disease Models, Animal; Halothane; In Vitro T | 1986 |
Porcine malignant hyperthermia: cell injury enhances halothane sensitivity of biopsies.
Topics: Animals; Caffeine; Disease Susceptibility; Halothane; Hybridization, Genetic; In Vitro Techniques; M | 1986 |
Electrophoresis of muscle proteins is not a method for diagnosis of malignant hyperthermia susceptibility.
Topics: Caffeine; Electrophoresis, Polyacrylamide Gel; Halothane; Humans; Malignant Hyperthermia; Molecular | 1986 |
Unexpected hyperthermia manifesting during outpatient anesthesia.
Topics: Adolescent; Anesthesia, General; Colonoscopy; Halothane; Humans; Lymphangiectasis, Intestinal; Male; | 1986 |
Malignant hyperthermia: is etomidate safe?
Topics: Animals; Blood Gas Analysis; Body Temperature; Etomidate; Fentanyl; Halothane; Heart Rate; Imidazole | 1985 |
Verapamil is not a therapeutic adjunct to dantrolene in porcine malignant hyperthermia.
Topics: Anesthesia, Inhalation; Animals; Blood Gas Analysis; Blood Pressure; Dantrolene; Drug Synergism; Hal | 1985 |
Malignant hyperpyrexia and sudden death.
Topics: Adolescent; Adult; Caffeine; Death, Sudden; Disease Susceptibility; Halothane; Humans; Male; Maligna | 1985 |
In vitro interaction between halothane and succinylcholine in human skeletal muscle: implications for malignant hyperthermia and masseter muscle rigidity.
Topics: Caffeine; Disease Susceptibility; Drug Interactions; Halothane; Humans; In Vitro Techniques; Maligna | 1985 |
The use of a platelet nucleotide assay as a possible diagnostic test for malignant hyperthermia.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Blood P | 1985 |
Porcine malignant hyperthermia susceptibility: erythrocytic osmotic fragility.
Topics: Animals; Creatine Kinase; Crosses, Genetic; Disease Susceptibility; Erythrocytes; Glutathione Peroxi | 1985 |
[A case of malignant hyperthermia; successful treatment with intravenous dantrolene sodium].
Topics: Anesthesia, Inhalation; Child, Preschool; Dantrolene; Female; Halothane; Humans; Injections, Intrave | 1985 |
Laboratory diagnosis of malignant hyperpyrexia susceptibility (MHS). European MH Group.
Topics: Caffeine; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia | 1985 |
Microcalorimetric studies in malignant hyperpyrexia susceptible individuals.
Topics: Blood Platelets; Body Temperature Regulation; Caffeine; Calorimetry; Disease Susceptibility; Halotha | 1985 |
Diltiazem inhibits halothane-induced contractions in malignant hyperthermia-susceptible muscles in vitro.
Topics: Animals; Benzazepines; Caffeine; Depression, Chemical; Diltiazem; Disease Susceptibility; Halothane; | 1985 |
Unusual response following use of succinylcholine in a horse anesthetized with halothane.
Topics: Anesthesia, General; Animals; Female; Halothane; Horse Diseases; Horses; Malignant Hyperthermia; Mus | 1985 |
[Determination of intracellular free calcium concentration, in vivo, in swine susceptible to malignant hyperthermia syndrome].
Topics: Animals; Calcium; Dantrolene; Halothane; Malignant Hyperthermia; Membrane Potentials; Muscle Contrac | 1985 |
Myoadenylate deaminase deficiency and malignant hyperthermia susceptibility: is there a relationship?
Topics: Adenylate Kinase; Adult; AMP Deaminase; Caffeine; Creatine Kinase; Disease Susceptibility; Female; H | 1985 |
Letter: Procaine and malignant hyperthermia.
Topics: Animals; Caffeine; Drug Interactions; Guinea Pigs; Halothane; Malignant Hyperthermia; Muscle Rigidit | 1974 |
Biochemical studies on malignant hyperpyrexia.
Topics: Adenosine Triphosphatases; Anesthesia, General; Animals; Calcium; Creatine Kinase; Glucosyltransfera | 1973 |
Malignant hyperthermia in a family.
Topics: Adenosine Triphosphatases; Anesthesia, General; Barbiturates; Biopsy; Cell Membrane; Creatine Kinase | 1973 |
Hereditary malignant hyperpyrexia associated with muscle adenylate kinase deficiency.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adult; Child; Creatine Kinase; Electrophoresis, Sta | 1974 |
[Malignant hyperthermia syndrome].
Topics: Adolescent; Anesthetics; Female; Halothane; Humans; Malignant Hyperthermia; Scoliosis; Succinylcholi | 1974 |
Malignant hyperpyrexia in the cat.
Topics: Anesthesia, Inhalation; Animals; Animals, Laboratory; Cat Diseases; Cats; Decamethonium Compounds; E | 1974 |
Editorial: New causes of malignant hyperpyrexia.
Topics: Anesthetics; Dexamethasone; Halothane; Humans; Malignant Hyperthermia; Nitrous Oxide; Succinylcholin | 1974 |
[Syndrome of malignant hyperthermia].
Topics: Adolescent; Halothane; Humans; Male; Malignant Hyperthermia; Succinylcholine; Syndrome | 1974 |
Proceedings: Studies of the therapeutic value of procaine and lignocaine in malignant hyperpyrexia.
Topics: Animals; Calcium; Diaphragm; Drug Evaluation; Halothane; Humans; In Vitro Techniques; Lidocaine; Mal | 1974 |
[Malignant hyperthermia--clinical aspects and treatment of life-endangering complications of anesthesia].
Topics: Acidosis; Acute Kidney Injury; Anesthesia, General; Brain Edema; Calcium; Cell Membrane Permeability | 1974 |
Malignant hyperthermia.
Topics: Anesthesia, Inhalation; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscles | 1974 |
New Zealand Committee on Adverse Drug Reactions. Eighth annual report.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Anti-Ba | 1973 |
Facilitation by oxygen of an induced hyperpyrexia during general anesthesia in dogs.
Topics: Acidosis; Anesthesia, General; Animals; Blood Pressure; Body Temperature; Carbon Dioxide; Dinitrophe | 1974 |
Hyperthermia associated with ophthalmic surgery.
Topics: Anesthesia, General; Blepharoptosis; Child; Child, Preschool; Female; Fever; Halothane; Humans; Infu | 1974 |
Procaine in malignant hyperpyrexia.
Topics: Aged; Caffeine; Female; Halothane; Humans; In Vitro Techniques; Lidocaine; Malignant Hyperthermia; M | 1972 |
[2 cases of malignant hyperpyrexia--with special reference to successful treatment by femoral VA bypass].
Topics: Adult; Anesthesia, General; Arteriovenous Shunt, Surgical; Femoral Artery; Femoral Vein; Halothane; | 1972 |
Pale, soft exudative pork, porcine stress syndrome and malignant hyperpyrexia--an identity?
Topics: Anesthesia, Inhalation; Animals; Body Temperature; Body Water; Glycolysis; Halothane; Hydrogen-Ion C | 1972 |
Pathology of malignant hyperpyrexia.
Topics: Anesthesia, General; Animals; Biopsy; Calcium; Creatine Kinase; Halothane; Humans; Malignant Hyperth | 1973 |
Histopathological and neuropharmacological aspects of malignant hyperpyrexia.
Topics: Adult; Anesthesia, General; Caffeine; Child; Child, Preschool; Creatine Kinase; Female; Halothane; H | 1973 |
Malignant hyperpyrexia and the dental outpatient.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, General; Child; Child, Preschool; Creatine Kinase | 1973 |
Thyroid status in malignant hyperpyrexia.
Topics: Animals; Halothane; Malignant Hyperthermia; Succinylcholine; Swine; Thyroid Hormones | 1973 |
Malignant hyperthermia: a catastrophic complication.
Topics: Anesthesia, General; Bicarbonates; Cryotherapy; Halothane; Humans; Hyperkalemia; Insulin; Malignant | 1973 |
Malignant hyperpyrexia in Australia and New Zealand.
Topics: Adolescent; Adult; Anesthesia, General; Australia; Child; Child, Preschool; Creatine Kinase; Cryothe | 1973 |
Erythrocyte osmotic fragility in hyperthermia-susceptible swine.
Topics: Animals; Cell Membrane; Disease Models, Animal; Erythrocytes; Halothane; Hemolysis; Malignant Hypert | 1973 |
Rise in serum creatine phosphokinase associated with agents used in anaesthesia.
Topics: Adolescent; Anesthesia, General; Anesthetics; Child; Child, Preschool; Creatine Kinase; Female; Halo | 1973 |
Malignant hyperpyrexia in a Negro.
Topics: Black or African American; Black People; Gallamine Triethiodide; Halothane; Humans; Male; Malignant | 1973 |
Malignant hyperpyrexia.
Topics: Ethyl Ethers; Halothane; Humans; Malignant Hyperthermia; Succinylcholine | 1973 |
Malignant hyperpyrexia.
Topics: Adolescent; Adult; Biopsy; Child; Child, Preschool; Creatine Kinase; Female; Halothane; Humans; Male | 1973 |
Recent advances in the understanding of anaesthetic-induced malignant hyperpyrexia.
Topics: Acidosis; Anesthetics; Animals; Anura; Bicarbonates; Caffeine; Calcium; Cold Temperature; Disease Mo | 1973 |
A new screening test for susceptibility to malignant hyperpyrexia.
Topics: Diagnosis, Differential; Halothane; Humans; Malignant Hyperthermia; Methods; Muscle Contraction | 1973 |
Malignant hyperthermia: an investigation of five patients.
Topics: Adolescent; Adult; Aspartate Aminotransferases; Calcium; Clinical Enzyme Tests; Creatine Kinase; Ele | 1973 |
[Limited anesthetic possibilities in patients with hereditary muscular diseases].
Topics: Aminosalicylic Acids; Anesthesia, General; Autopsy; Child; Child, Preschool; Death, Sudden; Fever; H | 1973 |
Letter: Malignant hyperthermia in the dog.
Topics: Anesthesia, Inhalation; Animals; Creatine Kinase; Dog Diseases; Dogs; Female; Fructose-Bisphosphate | 1973 |
Althesin and malignant hyperpyrexia.
Topics: Anesthetics; Animals; Body Temperature; Drug Combinations; Halothane; Hydroxysteroids; Intubation, I | 1973 |
[Malignant hyperthermia during anesthesia].
Topics: Adult; Anesthesia, Endotracheal; Animals; Autopsy; Brain Edema; Chick Embryo; Halothane; Hand; Heart | 1973 |
Malignant hyperpyrexia myopathy.
Topics: Adolescent; Adult; Anesthesia, General; Atrophy; Biopsy; Child; Child, Preschool; Female; Halothane; | 1973 |
A possible mechanism for induction of porcine malignant hyperthermia syndrome.
Topics: Animals; Female; Glutamates; Halothane; In Vitro Techniques; Malates; Malignant Hyperthermia; Mitoch | 1974 |
Porcine malignant hyperthermia: observations on the occurrence of pale, soft, exudative musculature among susceptible pigs.
Topics: Adenosine Triphosphate; Animals; Calcium; Creatine Kinase; Halothane; Hydrogen-Ion Concentration; La | 1974 |
Biochemical basis of malignant hyperpyrexia.
Topics: Biopsy; Caffeine; Calcium; Cell Membrane; Creatine Kinase; Extracellular Space; Halothane; Humans; I | 1974 |
Malignant hyperthermia.
Topics: Anesthesia; Atropine; Bicarbonates; Creatine Kinase; Cyclopropanes; Female; Halothane; Humans; Hydro | 1974 |
Malignant hyperthermia in a family: a clinical and serological investigation of 139 members.
Topics: Adult; Aged; Anesthesia, Inhalation; Child; Child, Preschool; Creatine Kinase; Female; Halothane; He | 1974 |
Haematological and cardiorespiratory responses to induced hyperpyrexia.
Topics: Acid-Base Equilibrium; Animals; Blood Coagulation Tests; Blood Pressure; Blood Volume; Carbon Dioxid | 1974 |
[Malignant hyperthermia].
Topics: Anesthesia, Inhalation; Female; Halothane; Humans; Infant; Malignant Hyperthermia; Succinylcholine | 1974 |
Screening for malignant hyperpyrexia.
Topics: Acidosis; Adolescent; Adult; Anesthesia, General; Biopsy; Child; Child, Preschool; Creatine Kinase; | 1972 |
Anesthetic malignant myopathy hyperthermia.
Topics: Acidosis; Adolescent; Anesthesia, Inhalation; Autopsy; Brain Edema; Cold Temperature; Female; Haloth | 1972 |