halothane has been researched along with Allodynia in 9 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, halothane-induced hyperalgesia during learning clouds interpreting enhanced retention performance solely as a memory consolidation effect." | 1.33 | Memory enhancing effect of low-dose sevoflurane does not occur in basolateral amygdala-lesioned rats. ( Alkire, MT; McReynolds, JR; Nathan, SV, 2005) |
| "To evaluate hyperalgesia, paw withdrawal latency (PWL) to radiant heat was measured before nerve constriction and five times after the constriction; just before TENS and at 1, 3, 7, and 14 days after the completion of TENS." | 1.32 | Long-lasting effect of transcutaneous electrical nerve stimulation on the thermal hyperalgesia in the rat model of peripheral neuropathy. ( Inoue, T; Mashimo, T; Nishimura, M; Sakaue, G; Shibata, M; Shibata, SC; Takenoshita, M, 2003) |
| "Hyperalgesia was assessed as a decrease in the time to withdrawal of a rat hind paw exposed to heat." | 1.31 | Inhaled anesthetics have hyperalgesic effects at 0.1 minimum alveolar anesthetic concentration. ( Dutton, RC; Eger, EI; Sonner, JM; Zhang, Y, 2000) |
| "After plantar incision, persistent hyperalgesia was observed immediately adjacent to or directly on the incision to punctate and blunt mechanical stimuli, respectively." | 1.30 | Primary and secondary hyperalgesia in a rat model for human postoperative pain. ( Brennan, TJ; Zahn, PK, 1999) |
| "The possibility is discussed that the hyperalgesia noted above results from a permanently reduced turnover of brain serotonin produced by halothane present in brain at days 10-15 of gestation." | 1.26 | Behavioral and neurochemical effects of prenatal halothane. ( Bowman, RE; Smith, RF, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ribeiro, NM | 1 |
| Toniolo, EF | 1 |
| Castro, LM | 1 |
| Russo, LC | 1 |
| Rioli, V | 1 |
| Ferro, ES | 1 |
| Dale, CS | 1 |
| Inoue, T | 1 |
| Takenoshita, M | 1 |
| Shibata, M | 1 |
| Nishimura, M | 1 |
| Sakaue, G | 1 |
| Shibata, SC | 1 |
| Mashimo, T | 1 |
| Weber, NC | 1 |
| Toma, O | 1 |
| Awan, S | 1 |
| Frässdorf, J | 1 |
| Preckel, B | 1 |
| Schlack, W | 1 |
| Alkire, MT | 1 |
| Nathan, SV | 1 |
| McReynolds, JR | 1 |
| Wen, YR | 1 |
| Yeh, GC | 1 |
| Shyu, BC | 1 |
| Ling, QD | 1 |
| Wang, KC | 1 |
| Chen, TL | 1 |
| Sun, WZ | 1 |
| Ji, RR | 1 |
| Rupp, F | 1 |
| Zahn, PK | 1 |
| Brennan, TJ | 1 |
| Zhang, Y | 1 |
| Eger, EI | 1 |
| Dutton, RC | 1 |
| Sonner, JM | 1 |
| Bowman, RE | 1 |
| Smith, RF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intranasal Nicotine for Postoperative Pain Treatment: A Comparison of Its Effects in the Context of Isoflurane-induced Anesthesia Versus Propofol Anesthesia[NCT00232817] | Phase 4 | 80 participants (Actual) | Interventional | 2003-07-31 | Completed | ||
| The Effects of Propofol vs. Sevoflurane Administered During Anesthesia Maintenance on Early and Late Recovery After Gynecological Surgery[NCT01755234] | Phase 4 | 90 participants (Actual) | Interventional | 2012-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Total opioid use in the post operative care unit (Mg of morphine equivalents) (NCT01755234)
Timeframe: PACU admission to discharge
| Intervention | miligrams of morphine equivalents (Median) |
|---|---|
| Sevoflurane | 9 |
| Propofol | 9.4 |
Opioid use in mg of morphine equivalents from discharge from the post anesthesia care unit to 24 hours after PACU discharge. (NCT01755234)
Timeframe: Discharge from PACU to 24 hours post operative after PACU discharge.
| Intervention | mg morphine equivalents (Median) |
|---|---|
| Sevoflurane | 30 |
| Propofol | 25 |
"Numeric rating scale for pain on a scale of 0-10 (0 is no pain and 10 is high pain) versus time curve in the post anesthesia care unit ( score * min). A higher value indicates more pain and time in the Post Anesthesia Care Unit.~The range is 0 pain to x time in minutes x 1 hour to 5 hour ( 60-300 minutes) . The pain scores were collected at 15 minute intervals from the time of admission to the PACU. The area under the NRS pain scale versus time curve was calculated using the trapezoidal method as an indicator of pain burden during early recovery (Graph Pad Prism ver 5.03, Graph Pad Software INC." (NCT01755234)
Timeframe: Time in the post anesthesia care unit
| Intervention | Pain Score * minutes in PACU (Median) |
|---|---|
| Sevoflurane | 270 |
| Propofol | 240 |
Quality of recovery score 24 hours after the surgical procedure.Score of 40 is poor recovery and a score of 200 is good recovery. (NCT01755234)
Timeframe: 24 hours after the surgical procedure
| Intervention | units on a scale (Median) |
|---|---|
| Sevoflurane | 175 |
| Propofol | 176 |
9 other studies available for halothane and Allodynia
| Article | Year |
|---|---|
AGH is a new hemoglobin alpha-chain fragment with antinociceptive activity.
Topics: Amino Acid Motifs; Analgesics; Animals; Carrageenan; Halothane; Hemoglobins; Humans; Hyperalgesia; I | 2013 |
Long-lasting effect of transcutaneous electrical nerve stimulation on the thermal hyperalgesia in the rat model of peripheral neuropathy.
Topics: Anesthetics, Inhalation; Animals; Constriction; Disease Models, Animal; Halothane; Hot Temperature; | 2003 |
Effects of nitrous oxide on the rat heart in vivo: another inhalational anesthetic that preconditions the heart?
Topics: Amygdala; Anesthetics, Inhalation; Animals; Avoidance Learning; Desflurane; Excitatory Amino Acid Ag | 2005 |
Memory enhancing effect of low-dose sevoflurane does not occur in basolateral amygdala-lesioned rats.
Topics: Amygdala; Anesthetics, Inhalation; Animals; Avoidance Learning; Desflurane; Excitatory Amino Acid Ag | 2005 |
A minimal stress model for the assessment of electroacupuncture analgesia in rats under halothane.
Topics: Acupuncture Analgesia; Anesthetics, Inhalation; Animals; Disease Models, Animal; Electroacupuncture; | 2007 |
Phosphorylation of transcription factor CREB in rat spinal cord after formalin-induced hyperalgesia: relationship to c-fos induction.
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; Excitatory Amino Acid Ant | 1997 |
Primary and secondary hyperalgesia in a rat model for human postoperative pain.
Topics: Anesthetics, Inhalation; Animals; Halothane; Humans; Hyperalgesia; Male; Pain, Postoperative; Physic | 1999 |
Inhaled anesthetics have hyperalgesic effects at 0.1 minimum alveolar anesthetic concentration.
Topics: Anesthetics, Inhalation; Animals; Chlorofluorocarbons; Cyclobutanes; Ether; Halothane; Hyperalgesia; | 2000 |
Inhaled anesthetics have hyperalgesic effects at 0.1 minimum alveolar anesthetic concentration.
Topics: Anesthetics, Inhalation; Animals; Chlorofluorocarbons; Cyclobutanes; Ether; Halothane; Hyperalgesia; | 2000 |
Inhaled anesthetics have hyperalgesic effects at 0.1 minimum alveolar anesthetic concentration.
Topics: Anesthetics, Inhalation; Animals; Chlorofluorocarbons; Cyclobutanes; Ether; Halothane; Hyperalgesia; | 2000 |
Inhaled anesthetics have hyperalgesic effects at 0.1 minimum alveolar anesthetic concentration.
Topics: Anesthetics, Inhalation; Animals; Chlorofluorocarbons; Cyclobutanes; Ether; Halothane; Hyperalgesia; | 2000 |
Behavioral and neurochemical effects of prenatal halothane.
Topics: Abnormalities, Drug-Induced; Animals; Behavior, Animal; Brain; Dopamine; Environmental Exposure; Fem | 1977 |