halothane and Aging
halothane has been researched along with Aging in 75 studies
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors investigated the cardiovascular and regional hemodynamic changes that occur in the aged rat under unanesthetized control conditions and during the induction of halothane anesthesia." | 7.66 | Cardiovascular and regional blood flow changes during halothane anesthesia in the aged rat. ( Albrecht, RF; Hoffman, WE; Miletich, DJ, 1982) |
| "The cardiovascular effects of halothane anesthesia in a mixture of nitrous oxide and oxygen were studied on piglets 7 hr to 25 days of age." | 7.65 | Age-dependent cardiovascular effects of halothane anesthesia in neonatal pigs. ( Crane, L; Gootman, N; Gootman, PM, 1975) |
| "Anesthesia was induced and maintained with N2O:O2 2:1 and 1 minimum alveolar concentration end-tidal halothane." | 5.08 | Pipecuronium revisited: dose-response and maintenance requirement in infants, children, and adults. ( Erkola, O; Meretoja, OA, 1997) |
| "To define the effect of aging on the pharmacokinetics of volatile anesthetics, we determined the end-tidal and mixed expired anesthetic concentrations of isoflurane, enflurane, halothane, and methoxyflurane during 30 min of simultaneous administration and for 5-12 days of elimination in seven healthy young patients (31 +/- 1." | 3.68 | Age affects the pharmacokinetics of inhaled anesthetics in humans. ( Carpenter, RL; Eger, EI; Johnson, BH; Strum, DP; Unadkat, JD, 1991) |
| "To evaluate the effect of aging on the distribution, clearance, and neuromuscular junction sensitivity to atracurium, the authors determined the pharmacokinetics and pharmacodynamics of atracurium in five healthy elderly subjects (74-76 yr) during halothane-nitrous oxide anesthesia and compared these values to those obtained previously in five healthy young adults (22-44 yr)." | 3.68 | Pharmacokinetics and pharmacodynamics of atracurium in the elderly. ( Caldwell, JE; Canfell, PC; Fahey, MR; Fisher, DM; Heier, T; Kitts, JB; Miller, RD; Spellman, MJ, 1990) |
| "Vecuronium kinetics and dynamics were determined in five infants (3 to 11 months old) and five children (1 to 5 years old) during anesthesia with 70% nitrous oxide and 0." | 3.67 | Vecuronium kinetics and dynamics in anesthetized infants and children. ( Castagnoli, K; Fisher, DM; Miller, RD, 1985) |
| "The authors investigated the cardiovascular and regional hemodynamic changes that occur in the aged rat under unanesthetized control conditions and during the induction of halothane anesthesia." | 3.66 | Cardiovascular and regional blood flow changes during halothane anesthesia in the aged rat. ( Albrecht, RF; Hoffman, WE; Miletich, DJ, 1982) |
| "The cardiovascular effects of halothane anesthesia in a mixture of nitrous oxide and oxygen were studied on piglets 7 hr to 25 days of age." | 3.65 | Age-dependent cardiovascular effects of halothane anesthesia in neonatal pigs. ( Crane, L; Gootman, N; Gootman, PM, 1975) |
| "We determined the cumulative dose-response relations of pipecuronium in infants and children during nitrous oxidehalothane anesthesia." | 2.67 | Clinical pharmacology of pipecuronium in infants and children during halothane anesthesia. ( Brandom, BW; Cook, DR; Dong, ML; Pickle, D; Sarner, JB; Weinberger, MJ, 1990) |
| "Halothane induced a lower negative inotropic effect in senescent rats (1." | 1.31 | Myocardial effects of halothane and isoflurane in senescent rats. ( Besse, S; Coriat, P; Riou, B; Rozenberg, S; Vivien, B, 2002) |
| "Halothane was a more potent depressant of cardiac function than isoflurane and developmental differences were more evident with this agent." | 1.29 | Direct myocardial effects of halothane and isoflurane. Comparison between adult and infant rabbits. ( Bosnjak, ZJ; Kampine, JP; Mehner, RW; Palmisano, BW; Stowe, DF, 1994) |
| "There were 47 episodes of gastro-oesophageal reflux (17." | 1.29 | Gastro-oesophageal reflux during anaesthesia in the dog: the effect of age, positioning and type of surgical procedure. ( Galatos, AD; Raptopoulos, D, 1995) |
| "The dose recommendations for atropine in anesthetized children vary, and the dose-response for heart rate has not been defined." | 1.28 | Dose-response for atropine and heart rate in infants and children anesthetized with halothane and nitrous oxide. ( Brown, MP; Palmisano, BW; Setlock, MA; Siker, D; Tripuraneni, R, 1991) |
| "Bupivacaine was infused at a constant rate while the pigs' ECGs and EEGs were recorded." | 1.28 | Bupivacaine toxicity in young pigs is age-dependent and is affected by volatile anesthetics. ( Badgwell, JM; Heavner, JE; Kytta, J, 1990) |
| " They then compared these dose-response relationships with values obtained for adults (greater than 18 years old) under comparable anesthetic conditions." | 1.27 | Neuromuscular effects of vecuronium (ORG NC45) in infants and children during N2O, halothane anesthesia. ( Fisher, DM; Miller, RD, 1983) |
| "Alfentanil is a potent short-acting opioid analgesic which depresses respiration and can cause cardiovascular depression." | 1.27 | The pharmacokinetics and clinical effects of a low dose of alfentanil in elderly patients. ( Bower, S; Dodson, ME; Kent, AP, 1988) |
| "05), thus a parallel shift of the dose-response curves was observed." | 1.27 | Comparison of the effects of halothane on newborn and adult rabbit myocardium. ( Krane, EJ; Su, JY, 1987) |
| " The elimination half-life (t beta 1/2) was 174 +/- 60 min in neonates, significantly longer than the values of 90 +/- 23 and 89 +/- 18 min in children and adults, respectively." | 1.26 | Pharmacokinetics and pharmacodynamics of d-tubocurarine in infants, children, and adults. ( Cronnelly, R; Fisher, DM; Gregory, GA; Miller, RD; O'Keeffe, C; Stanski, DR, 1982) |
| "Halothane was tested only at its maximum tolerated dose, and histologic examination was performed only on tumor masses and other grossly abnormal tissues found at necropsy." | 1.26 | Carcinogenicity of halothane in Swiss/ICR mice. ( Baden, JM; Kosek, JC; Mazze, RI; Rice, SA; Wharton, RS, 1979) |
Research
Studies (75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (54.67) | 18.7374 |
| 1990's | 24 (32.00) | 18.2507 |
| 2000's | 10 (13.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Johnson, CB | 1 |
| Sylvester, SP | 1 |
| Stafford, KJ | 1 |
| Mitchinson, SL | 1 |
| Ward, RN | 1 |
| Mellor, DJ | 1 |
| Rozenberg, S | 1 |
| Besse, S | 1 |
| Vivien, B | 1 |
| Coriat, P | 1 |
| Riou, B | 1 |
| Prakash, YS | 2 |
| Hunter, LW | 1 |
| Seckin, I | 1 |
| Sieck, GC | 2 |
| Chaves, AA | 1 |
| Dech, SJ | 1 |
| Nakayama, T | 1 |
| Hamlin, RL | 1 |
| Bauer, JA | 1 |
| Carnes, CA | 1 |
| Shumilla, JA | 1 |
| Sweitzer, SM | 1 |
| Eger, EI | 6 |
| Laster, MJ | 1 |
| Kendig, JJ | 1 |
| Fisher, DM | 4 |
| Miller, RD | 4 |
| Boudreaux, JP | 1 |
| Schieber, RA | 1 |
| Cook, DR | 4 |
| Lerman, J | 2 |
| Gregory, GA | 4 |
| Willis, MM | 2 |
| Rao, CC | 1 |
| Dierdorf, SF | 1 |
| Wolfe, TM | 1 |
| Haselby, KA | 1 |
| Krishna, G | 1 |
| Paradise, RR | 1 |
| Friesen, RH | 1 |
| Wear, R | 1 |
| Robinson, S | 1 |
| Hoffman, WE | 3 |
| Miletich, DJ | 3 |
| Albrecht, RF | 3 |
| O'Keeffe, C | 1 |
| Stanski, DR | 1 |
| Cronnelly, R | 1 |
| Kristoffersen, MB | 1 |
| Kjaer Hansen, EK | 1 |
| Jostell, KG | 1 |
| Stockman, O | 1 |
| Mirakhur, RK | 1 |
| Jones, CJ | 1 |
| Brandom, BW | 2 |
| Shiu, G | 1 |
| Wolfson, B | 1 |
| Gronert, GA | 1 |
| Handler, SD | 1 |
| Ream, RS | 1 |
| Schreiner, MS | 1 |
| Neff, JD | 1 |
| McRae, KM | 1 |
| Jawad, AF | 1 |
| Scherer, PW | 1 |
| Neufeld, GR | 1 |
| Brian, JE | 1 |
| Slaven, JS | 1 |
| Kennedy, RH | 2 |
| Seifen, E | 2 |
| Patel, R | 1 |
| Lenczyk, M | 1 |
| Hannallah, RS | 1 |
| McGill, WA | 1 |
| Palmisano, BW | 2 |
| Mehner, RW | 1 |
| Stowe, DF | 1 |
| Bosnjak, ZJ | 1 |
| Kampine, JP | 1 |
| Bhattacharyya, BJ | 1 |
| Tsen, K | 1 |
| Sokoll, MD | 1 |
| Peinado, A | 1 |
| Yuste, R | 1 |
| Katz, LC | 1 |
| Galatos, AD | 1 |
| Raptopoulos, D | 1 |
| Taguchi, N | 1 |
| Nishikawa, T | 1 |
| Inomata, S | 1 |
| Taguchi, M | 1 |
| Yamashita, S | 1 |
| Naito, H | 1 |
| Wieland, SJ | 1 |
| Gong, QH | 1 |
| Fletcher, JE | 1 |
| Rosenberg, H | 1 |
| Meretoja, OA | 1 |
| Erkola, O | 1 |
| Cody, MJ | 1 |
| Hannon, JD | 1 |
| Housmans, PR | 1 |
| Driessen, JJ | 1 |
| Robertson, EN | 1 |
| Van Egmond, J | 1 |
| Booij, LH | 1 |
| Erb, C | 1 |
| Troost, J | 1 |
| Kopf, S | 1 |
| Schmitt, U | 1 |
| Löffelholz, K | 1 |
| Soreq, H | 1 |
| Klein, J | 1 |
| Hartman, PS | 1 |
| Ishii, N | 1 |
| Kayser, EB | 1 |
| Morgan, PG | 1 |
| Sedensky, MM | 1 |
| Gip, P | 1 |
| Hagiwara, G | 1 |
| Ruby, NF | 1 |
| Heller, HC | 1 |
| Baden, JM | 1 |
| Mazze, RI | 1 |
| Wharton, RS | 1 |
| Rice, SA | 1 |
| Kosek, JC | 1 |
| Danzmann, E | 1 |
| Poppelbaum, HF | 1 |
| Cardan, E | 1 |
| Crane, L | 1 |
| Gootman, N | 1 |
| Gootman, PM | 2 |
| Drake, WT | 1 |
| Creighan, M | 1 |
| Sims, DE | 1 |
| Ochiai, R | 1 |
| Guthrie, RD | 1 |
| Motoyama, EK | 1 |
| Lynn, AM | 1 |
| McRorie, TI | 1 |
| Slattery, JT | 1 |
| Calkins, DF | 1 |
| Opheim, KE | 1 |
| Kalow, W | 1 |
| Sharer, S | 1 |
| Britt, B | 1 |
| Takenoshita, M | 1 |
| Steinbach, JH | 1 |
| Setlock, MA | 1 |
| Brown, MP | 1 |
| Siker, D | 1 |
| Tripuraneni, R | 1 |
| Strum, DP | 1 |
| Unadkat, JD | 1 |
| Johnson, BH | 1 |
| Carpenter, RL | 1 |
| Dwyer, RC | 1 |
| Fee, JP | 1 |
| Howard, PJ | 1 |
| Clarke, RS | 1 |
| Murat, I | 1 |
| Hoerter, J | 1 |
| Ventura-Clapier, R | 1 |
| Sarner, JB | 1 |
| Dong, ML | 1 |
| Pickle, D | 1 |
| Weinberger, MJ | 1 |
| Kitts, JB | 1 |
| Canfell, PC | 1 |
| Spellman, MJ | 1 |
| Caldwell, JE | 1 |
| Heier, T | 1 |
| Fahey, MR | 1 |
| Kitahara, Y | 1 |
| Kojima, Y | 1 |
| Nozaki, F | 1 |
| Badgwell, JM | 1 |
| Heavner, JE | 1 |
| Kytta, J | 1 |
| Loss, GE | 1 |
| Seifen, AB | 1 |
| Kurth, CD | 1 |
| Hutchison, AA | 1 |
| Caton, DC | 1 |
| Davenport, PW | 1 |
| Jorch, G | 1 |
| Woike, H | 1 |
| Rabe, H | 1 |
| Reinhold, P | 1 |
| Debaene, B | 1 |
| Meistelman, C | 1 |
| d'Hollander, A | 1 |
| Lind, RC | 1 |
| Gandolfi, AJ | 1 |
| Hall, PD | 1 |
| Krane, EJ | 2 |
| Su, JY | 2 |
| Yasuda, N | 1 |
| Targ, AG | 1 |
| Castagnoli, K | 1 |
| Kent, AP | 1 |
| Dodson, ME | 1 |
| Bower, S | 1 |
| Baughman, VL | 1 |
| Grandy, JL | 1 |
| Steffey, EP | 1 |
| Miller, M | 1 |
| Ording, H | 1 |
| Hansen, U | 1 |
| Skovgaard, LT | 1 |
| Levin, ED | 2 |
| Uemura, E | 2 |
| DeLuna, R | 1 |
| Franks, P | 1 |
| Bowman, RE | 2 |
| Busoni, P | 1 |
| Andreuccetti, T | 1 |
| Schmitt-Bantel, BI | 1 |
| James, OF | 1 |
| Martin-Body, RL | 1 |
| Sinclair, JD | 1 |
| Eger, RR | 1 |
| Seals, C | 1 |
| Mosher, GL | 1 |
| Robinson, RH | 1 |
| Crane, LA | 1 |
| Gootman, NL | 1 |
| Kitamura, H | 1 |
| Sawa, T | 1 |
| Ikezono, E | 1 |
Clinical Trials (3)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Comparison of the Airway Deadspace Associated With the Air-Q® and Endotracheal Tube Using Volumetric Capnography in Young Children[NCT03785977] | 62 participants (Actual) | Observational | 2019-03-25 | Completed | |||
| Apneic Oxygenation to Prevent Oxygen Desaturation During Intubation in the NICU[NCT05451953] | 110 participants (Anticipated) | Interventional | 2022-07-21 | Recruiting | |||
| Influence of Sevoflurane and Propofol on Maximum Muscular Strength, Speed of Contraction and Relaxation, in Humans: A Pilot Study[NCT05615025] | Phase 3 | 48 participants (Actual) | Interventional | 2023-01-20 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
2 reviews available for halothane and Aging
| Article | Year |
|---|---|
Newborn anaesthesia: pharmacological considerations.
Topics: Aging; Anesthesia; Anesthesia, Inhalation; Cardiovascular Diseases; Dose-Response Relationship, Drug | 1986 |
Drugs and the ageing liver.
Topics: Aged; Aging; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Syst | 1985 |
Trials
4 trials available for halothane and Aging
| Article | Year |
|---|---|
Hemodynamic effects of intravenous ephedrine in infants and children anesthetized with halothane and nitrous oxide.
Topics: Adolescent; Adrenergic Agonists; Aging; Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Press | 1996 |
Pipecuronium revisited: dose-response and maintenance requirement in infants, children, and adults.
Topics: Adult; Aging; Anesthesia; Anesthetics, Inhalation; Child; Child, Preschool; Dose-Response Relationsh | 1997 |
The time-course of action and recovery of rocuronium 0.3 mg x kg(-1) in infants and children during halothane anaesthesia measured with acceleromyography.
Topics: Aging; Androstanols; Anesthesia, Inhalation; Anesthetics, Inhalation; Child, Preschool; Elective Sur | 2000 |
Clinical pharmacology of pipecuronium in infants and children during halothane anesthesia.
Topics: Aging; Androstane-3,17-diol; Androstanols; Anesthesia, Inhalation; Child, Preschool; Clinical Trials | 1990 |
Other Studies
69 other studies available for halothane and Aging
| Article | Year |
|---|---|
Effects of age on the electroencephalographic response to castration in lambs anaesthetized with halothane in oxygen from birth to 6 weeks old.
Topics: Aging; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Electroencephalography; Halothane; | 2009 |
Myocardial effects of halothane and isoflurane in senescent rats.
Topics: Aging; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Halothane; Isoflurane; Ma | 2002 |
Volatile anesthetics and regulation of cardiac Na+/Ca2+ exchange in neonates versus adults.
Topics: Aging; Anesthetics, Inhalation; Animals; Animals, Newborn; Calcium; Halothane; Heart; Heart Ventricl | 2002 |
Age and anesthetic effects on murine electrocardiography.
Topics: Aging; Anesthetics, Combined; Anesthetics, Inhalation; Animals; Disease Models, Animal; Electrocardi | 2003 |
Inhibition of spinal protein kinase C-epsilon or -gamma isozymes does not affect halothane minimum alveolar anesthetic concentration in rats.
Topics: Aging; Anesthetics, Inhalation; Animals; Enzyme Inhibitors; Halothane; Injections, Spinal; Protein K | 2004 |
Neuromuscular effects of vecuronium (ORG NC45) in infants and children during N2O, halothane anesthesia.
Topics: Adolescent; Adult; Aging; Anesthesia, Inhalation; Child; Child, Preschool; Electromyography; Halotha | 1983 |
Hemodynamic effects of halothane in the newborn piglet.
Topics: Aging; Animals; Animals, Newborn; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; | 1984 |
Age and solubility of volatile anesthetics in blood.
Topics: Adult; Aged; Aging; Anesthetics; Blood Gas Analysis; Child; Child, Preschool; Cholesterol; Enflurane | 1984 |
Effect of age on epinephrine-induced arrhythmias during halothane anaesthesia in pigs.
Topics: Aging; Anesthesia, Inhalation; Animals; Arrhythmias, Cardiac; Epinephrine; Halothane; Heart; Hemodyn | 1984 |
The baroresponse and cardiovascular depression by halothane in infants.
Topics: Aging; Halothane; Humans; Infant; Pressoreceptors | 1983 |
The effect of halothane on the baroresponse of adult and baby rabbits.
Topics: Aging; Anesthesia; Animals; Animals, Newborn; Blood Pressure; Cardiac Output; Halothane; Heart Rate; | 1982 |
Cardiovascular and regional blood flow changes during halothane anesthesia in the aged rat.
Topics: Aging; Anesthesia; Animals; Blood Gas Analysis; Blood Pressure; Halothane; Hemodynamics; Male; Micro | 1982 |
Pharmacokinetics and pharmacodynamics of d-tubocurarine in infants, children, and adults.
Topics: Adolescent; Adult; Aging; Anesthesia, General; Child; Child, Preschool; Electromyography; Half-Life; | 1982 |
Chlormethiazole (Heminevrin), pethidine and nitrous oxide as compared to halothane for general anesthesia.
Topics: Aged; Aging; Anesthesia, General; Chlormethiazole; Halothane; Humans; Kinetics; Meperidine; Middle A | 1982 |
Atropine and glycopyrrolate: changes in cardiac rate and rhythm in conscious and anaesthetised children.
Topics: Adolescent; Aging; Anesthesia, General; Arrhythmias, Cardiac; Atropine; Body Weight; Child; Child, P | 1982 |
The inspired median effective dose, brain concentration at anesthesia, and cardiovascular index for halothane in young rats.
Topics: Aging; Anesthesia, Inhalation; Animals; Brain; Halothane; Heart Diseases; Myocardium; Rats | 1981 |
Contracture responses and energy stores in quadriceps muscle from humans age 7-82 years.
Topics: Adolescent; Adult; Aged; Aging; Caffeine; Child; Energy Metabolism; Halothane; Humans; Middle Aged; | 1980 |
Maturational influences on suppression of vocal cord function by anesthesia.
Topics: Aging; Animals; Dose-Response Relationship, Drug; Halothane; Movement; Rabbits; Respiration; Vocal C | 1995 |
Volumetric capnography in children. Influence of growth on the alveolar plateau slope.
Topics: Adolescent; Aging; Anesthesia; Body Constitution; Carbon Dioxide; Child; Child, Preschool; Halothane | 1995 |
The effect of age on halothane-induced alterations of contractility in isolated rat aorta.
Topics: Aging; Animals; Aorta; Endothelium, Vascular; Halothane; In Vitro Techniques; Male; Norepinephrine; | 1994 |
Age and the onset of desaturation in apnoeic children.
Topics: Adolescent; Aging; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous; Apnea; Body | 1994 |
Direct myocardial effects of halothane and isoflurane. Comparison between adult and infant rabbits.
Topics: Aging; Animals; Animals, Newborn; Atrioventricular Node; Coronary Circulation; Halothane; Heart; Hea | 1994 |
Age-induced alteration of neuromuscular transmission: effect of halothane.
Topics: Acetylcholine; Aging; Animals; Electrophysiology; Evoked Potentials; Halothane; Iontophoresis; Male; | 1994 |
Extensive dye coupling between rat neocortical neurons during the period of circuit formation.
Topics: Aging; Animals; Biotin; Cerebral Cortex; Dendrites; Electric Conductivity; Halothane; Intercellular | 1993 |
Gastro-oesophageal reflux during anaesthesia in the dog: the effect of age, positioning and type of surgical procedure.
Topics: Abdomen; Aging; Anesthesia; Anesthesia, Inhalation; Animals; Dog Diseases; Dogs; Esophagus; Female; | 1995 |
Altered sodium current response to intracellular fatty acids in halothane-hypersensitive skeletal muscle.
Topics: Aging; Disease Susceptibility; Electric Conductivity; Fatty Acids; Halothane; Humans; Intracellular | 1996 |
Comparison of volatile anesthetic effects on actin-myosin cross-bridge cycling in neonatal versus adult cardiac muscle.
Topics: Actins; Aging; Algorithms; Anesthetics, Inhalation; Animals; Animals, Newborn; Halothane; Heart; In | 2000 |
Compensatory mechanisms enhance hippocampal acetylcholine release in transgenic mice expressing human acetylcholinesterase.
Topics: Acetylcholine; Acetylcholinesterase; Aging; Anesthetics, Inhalation; Animals; Choline; Cholinesteras | 2001 |
Mitochondrial mutations differentially affect aging, mutability and anesthetic sensitivity in Caenorhabditis elegans.
Topics: Aging; Anesthetics, Inhalation; Animals; Caenorhabditis elegans; Electron Transport Complex I; Elect | 2001 |
Sleep deprivation decreases glycogen in the cerebellum but not in the cortex of young rats.
Topics: Aging; Anesthesia; Anesthetics, Inhalation; Animals; Animals, Newborn; Cerebellum; Cerebral Cortex; | 2002 |
Carcinogenicity of halothane in Swiss/ICR mice.
Topics: Adenoma; Aging; Animals; Carcinoma, Hepatocellular; Erythrocyte Count; Female; Halothane; Hemoglobin | 1979 |
[Pathophysiologic considerations on the problem of anesthesia in the aged].
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aged; Aging; Anesthesia; Blood Pressure; Cardiovascular Sys | 1979 |
Pancuronium requirements. With special reference to serum protein pattern.
Topics: Adult; Aged; Aging; Anesthesia; Blood Proteins; Body Weight; Female; Halothane; Humans; Male; Middle | 1979 |
Age-dependent cardiovascular effects of halothane anesthesia in neonatal pigs.
Topics: Aging; Anesthesia; Animals; Animals, Newborn; Blood Pressure; Halothane; Heart Rate; Hemodynamics; N | 1975 |
Limitations of monastral blue as a vascular label: rapid rate of clearance is age-dependent, and interactions with anesthetics depress arterial blood pressure in rats.
Topics: Aging; Anesthetics; Animals; Blood Pressure; Coloring Agents; Drug Interactions; Halothane; Indoles; | 1992 |
Differential sensitivity to halothane anesthesia of the genioglossus, intercostals, and diaphragm in kittens.
Topics: Aging; Animals; Carbon Dioxide; Cats; Depression, Chemical; Diaphragm; Dose-Response Relationship, D | 1992 |
Age-dependent morphine partitioning between plasma and cerebrospinal fluid in monkeys.
Topics: Aging; Animals; Animals, Newborn; Blood-Brain Barrier; Central Nervous System; Halothane; Infusions, | 1991 |
Pharmacogenetics of caffeine and caffeine-halothane contractures in biopsies of human skeletal muscle.
Topics: Adolescent; Adult; Aged; Aging; Caffeine; Child; Child, Preschool; Female; Genetic Variation; Haloth | 1991 |
Halothane blocks low-voltage-activated calcium current in rat sensory neurons.
Topics: Aging; Animals; Animals, Newborn; Calcium Channels; Evoked Potentials; Ganglia, Spinal; Halothane; I | 1991 |
Dose-response for atropine and heart rate in infants and children anesthetized with halothane and nitrous oxide.
Topics: Aging; Anesthesia, Inhalation; Atropine; Blood Pressure; Child; Child, Preschool; Dose-Response Rela | 1991 |
Age affects the pharmacokinetics of inhaled anesthetics in humans.
Topics: Adipose Tissue; Adult; Aged; Aged, 80 and over; Aging; Anesthesia, Inhalation; Anesthetics; Body Wei | 1991 |
Arterial washin of halothane and isoflurane in young and elderly adult patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Anesthesia, General; Anesthesia, Inhalation; Fema | 1991 |
Developmental changes in effects of halothane and isoflurane on contractile properties of rabbit cardiac skinned fibers.
Topics: Adenosine Triphosphatases; Aging; Animals; Animals, Newborn; Calcium; Embryonic and Fetal Developmen | 1990 |
Pharmacokinetics and pharmacodynamics of atracurium in the elderly.
Topics: Adult; Aged; Aging; Anesthesia, Inhalation; Atracurium; Halothane; Humans; Neuromuscular Junction; N | 1990 |
[Aperiodic analysis of EEG in children during halothane anesthesia].
Topics: Aging; Anesthesia, Inhalation; Child; Child, Preschool; Electroencephalography; Female; Halothane; H | 1990 |
Bupivacaine toxicity in young pigs is age-dependent and is affected by volatile anesthetics.
Topics: Aging; Animals; Arrhythmias, Cardiac; Blood Pressure; Bupivacaine; Cardiac Output; Drug Interactions | 1990 |
Aging: effects on minimum alveolar concentration (MAC) for halothane in Fischer-344 rats.
Topics: Aging; Animals; Body Temperature; Carbon Dioxide; Dose-Response Relationship, Drug; Halothane; Male; | 1989 |
Maturational and anesthetic effects on apneic thresholds in lambs.
Topics: Aging; Anesthesia; Animals; Carbon Dioxide; Halothane; Laryngeal Nerves; Respiration; Respiratory Ph | 1989 |
Influence of anesthetic induction with halothane and isoflurane on internal carotid blood flow velocity in early infancy.
Topics: Aging; Anesthesia; Blood Pressure; Carbon Dioxide; Carotid Arteries; Cerebrovascular Circulation; Fe | 1989 |
Recovery from vecuronium neuromuscular blockade following neostigmine administration in infants, children, and adults during halothane anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, Inhalation; Child; Child, Preschool; Halothane; Humans; Infant; Midd | 1989 |
Age and gender influence halothane-associated hepatotoxicity in strain 13 guinea pigs.
Topics: Aging; Anesthesia, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Female; Guinea Pigs; | 1989 |
Comparison of the effects of halothane on skinned myocardial fibers from newborn and adult rabbit: II. Effects on sarcoplasmic reticulum.
Topics: Aging; Animals; Animals, Newborn; Caffeine; Calcium; Halothane; Heart; In Vitro Techniques; Male; My | 1989 |
Solubility of I-653, sevoflurane, isoflurane, and halothane in human tissues.
Topics: Aged; Aging; Anesthetics; Chromatography, Gas; Desflurane; Ethers; Halothane; Humans; Isoflurane; Me | 1989 |
Vecuronium kinetics and dynamics in anesthetized infants and children.
Topics: Aging; Anesthesia; Child, Preschool; Female; Halothane; Humans; Infant; Infusions, Parenteral; Kinet | 1985 |
The pharmacokinetics and clinical effects of a low dose of alfentanil in elderly patients.
Topics: Aged; Aged, 80 and over; Aging; Alfentanil; Analgesics, Opioid; Anesthesia, Inhalation; Female; Fent | 1988 |
Effects of phenobarbital on cerebral blood flow and metabolism in young and aged rats.
Topics: Aging; Anesthesia, Inhalation; Animals; Blood Pressure; Brain; Carbon Dioxide; Cerebrovascular Circu | 1986 |
Arterial blood PO2 and PCO2 in horses during early halothane-oxygen anaesthesia.
Topics: Aging; Anesthesia, General; Animals; Blood Gas Analysis; Carbon Dioxide; Halothane; Horses; Oxygen | 1987 |
Age, fiber type composition and in vitro contracture responses in human malignant hyperthermia.
Topics: Adolescent; Adult; Aging; Caffeine; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; | 1988 |
Neurobehavioral effects of chronic halothane exposure during developmental and juvenile periods in the rat.
Topics: Aging; Animals; Behavior, Animal; Female; Halothane; Hippocampus; Male; Pregnancy; Rats; Rats, Inbre | 1987 |
Comparison of the effects of halothane on newborn and adult rabbit myocardium.
Topics: Aging; Animals; Female; Halothane; In Vitro Techniques; Male; Myocardial Contraction; Rabbits | 1987 |
The spread of caudal analgesia in children: a mathematical model.
Topics: Aging; Analgesia; Anesthesia, Caudal; Anesthesia, Epidural; Body Weight; Child; Child, Preschool; Ha | 1986 |
Effect of age on the solubility of volatile anesthetics in human tissues.
Topics: Adipose Tissue; Adult; Aged; Aging; Anesthesia, Inhalation; Brain; Enflurane; Halothane; Humans; Inf | 1986 |
Analysis of respiratory patterns in the awake and in the halothane anaesthetised rat.
Topics: Aging; Anesthesia, General; Animals; Carbon Dioxide; Consciousness; Female; Halothane; Rats; Rats, I | 1985 |
Effect of temperature and age on the solubility of enflurane, halothane, isoflurane, and methoxyflurane in human blood.
Topics: Adult; Aged; Aging; Chromatography, Gas; Enflurane; Halothane; Humans; Isoflurane; Methoxyflurane; M | 1985 |
Plasma and myocardial catecholamine levels in young and aged rats during halothane anesthesia.
Topics: Aging; Anesthesia, General; Animals; Blood Pressure; Catecholamines; Halothane; Heart Rate; Myocardi | 1985 |
Effects of halothane on synaptogenesis and learning behavior in rats.
Topics: Aging; Animals; Behavior, Animal; Female; Halothane; Learning; Pregnancy; Prenatal Exposure Delayed | 1985 |
Anesthesia for fractured hips. Innovar versus halothane.
Topics: Adult; Aged; Aging; Benperidol; Drug Combinations; Female; Fentanyl; Fractures, Bone; Halothane; Hip | 1972 |
The effects of decamethonium (C-10) on blood pressure and heart rate in newborn piglets.
Topics: Acetylcholine; Aging; Anesthesia; Animals; Animals, Newborn; Blood Pressure; Carbon Dioxide; Decamet | 1974 |
Postoperative hypoxemia: The contribution of age to the maldistribution of ventilation.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Aging; Anesthesia, General; Child; Female; Halothane | 1972 |