halothane has been researched along with Adverse Drug Event in 34 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Most adverse drug reactions affecting the liver and producing jaundice are unpredictable, delayed in onset, and only hypothetically related to microsomal metabolism in some instances." | 2.35 | Hepatic drug metabolism and adverse hepatic drug reactions. ( Schaffner, F, 1975) |
| "Dantrolene median dose was 50 (25-400) and 200 (25-400) mg·day -1 in responders and nonresponders, respectively." | 1.91 | Oral Dantrolene for Myopathic Symptoms in Malignant Hyperthermia-Susceptible Patients: A 25-Year Retrospective Cohort Study of Adverse Effects and Tolerability. ( Ibarra Moreno, CA; Jungbluth, H; Kraeva, N; Riazi, S; Voermans, NC; Zvaritch, E, 2023) |
| "5 million adverse drug reaction (ADR) reports for 8620 drugs/biologics that are listed for 1191 Coding Symbols for Thesaurus of Adverse Reaction (COSTAR) terms of adverse effects." | 1.32 | Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. ( Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL, 2004) |
| "Erythromycin was associated with two deaths." | 1.29 | Drug associated hepatic reactions in New Zealand: 21 years experience. ( Pillans, PI, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (73.53) | 18.7374 |
| 1990's | 3 (8.82) | 18.2507 |
| 2000's | 3 (8.82) | 29.6817 |
| 2010's | 2 (5.88) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Matthews, EJ | 1 |
| Kruhlak, NL | 1 |
| Weaver, JL | 1 |
| Benz, RD | 1 |
| Contrera, JF | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Ibarra Moreno, CA | 1 |
| Kraeva, N | 2 |
| Zvaritch, E | 1 |
| Jungbluth, H | 1 |
| Voermans, NC | 1 |
| Riazi, S | 2 |
| Timmins, MA | 1 |
| Rosenberg, H | 1 |
| Larach, MG | 1 |
| Sterling, C | 1 |
| Antoine, DJ | 1 |
| Williams, DP | 1 |
| Park, BK | 2 |
| Takahara, A | 1 |
| Sugiyama, A | 1 |
| Hashimoto, K | 1 |
| Venning, GR | 1 |
| Prescott, LF | 1 |
| Salaspuro, M | 1 |
| Holzbach, RT | 1 |
| Van Pelt, FN | 1 |
| Straub, P | 1 |
| Manns, MP | 1 |
| Jørgensen, G | 1 |
| Pillans, PI | 1 |
| Schaffner, F | 1 |
| Maddrey, WC | 1 |
| Boitnott, JK | 1 |
| Smuckler, EA | 1 |
| Sherlock, S | 1 |
| Caranasos, GJ | 1 |
| Mitchell, JR | 1 |
| Lauterburg, BH | 2 |
| Mörl, M | 1 |
| Zimmerman, HJ | 1 |
| Coleman, JW | 1 |
| James, OF | 1 |
| Siede, W | 1 |
| McQueen, EG | 1 |
| Fossati, C | 1 |
| Robertson, DM | 1 |
| Kirchmayer, S | 1 |
| Bondar', ZA | 1 |
| Podymova, SD | 1 |
| Bode, C | 1 |
| Martini, GA | 1 |
| Uhlír, O | 1 |
13 reviews available for halothane and Adverse Drug Event
| Article | Year |
|---|---|
Understanding the role of reactive metabolites in drug-induced hepatotoxicity: state of the science.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Animals; Biotransformation; Chemic | 2008 |
Reactive metabolites as a cause of hepatotoxicity.
Topics: Acetaminophen; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Drug-Related Side | 1983 |
Drug-induced liver disease.
Topics: Analgesics; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Chlorpromazine; Contracep | 1981 |
Molecular basis of drug-induced immunological liver injury.
Topics: Animals; Antibody Formation; Anticonvulsants; Chemical and Drug Induced Liver Injury; Dihydralazine; | 1995 |
Hepatic drug metabolism and adverse hepatic drug reactions.
Topics: Adaptation, Biological; Animals; Biotransformation; Carbon Tetrachloride; Carbon Tetrachloride Poiso | 1975 |
Drug-induced chronic hepatitis and cirrhosis.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adve | 1979 |
Iatrogenic disease, drug metabolism, and cell injury: lethal synthesis in man.
Topics: Biotransformation; Cell Survival; Chloroform; Diet; Drug-Related Side Effects and Adverse Reactions; | 1977 |
Drugs and the ageing liver.
Topics: Aged; Aging; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Syst | 1985 |
[Drug damage to the liver: role of reactive metabolites and pharmacokinetics].
Topics: Acetaminophen; Amiodarone; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adv | 1985 |
[Liver damage due to drugs. I].
Topics: Arsenicals; Chemical and Drug Induced Liver Injury; Chloramphenicol; Cholestasis; Coumarins; Drug-Re | 1974 |
The eye and adverse drug effects. Some selected considerations.
Topics: Acetazolamide; Amyl Nitrite; Anesthesia; Chloramphenicol; Chloroquine; Contraceptives, Oral; Dexamet | 1972 |
[Drug-induced hepatitis].
Topics: Adult; Anti-Bacterial Agents; Antimetabolites; Chemical and Drug Induced Liver Injury; Contraceptive | 1970 |
[Toxic liver injury].
Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Cholestyramine Resin; Contraceptives, Oral; Dia | 1970 |
21 other studies available for halothane and Adverse Drug Event
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Dru | 2004 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Oral Dantrolene for Myopathic Symptoms in Malignant Hyperthermia-Susceptible Patients: A 25-Year Retrospective Cohort Study of Adverse Effects and Tolerability.
Topics: Dantrolene; Drug-Related Side Effects and Adverse Reactions; Fatigue; Halothane; Humans; Malignant H | 2023 |
Malignant hyperthermia testing in probands without adverse anesthetic reaction.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Dantrolene; Drug-Related Side Effects an | 2015 |
Reduction of repolarization reserve by halothane anaesthesia sensitizes the guinea-pig heart for drug-induced QT interval prolongation.
Topics: Action Potentials; Adrenergic beta-Antagonists; Algorithms; Anesthetics, Inhalation; Animals; Chroma | 2005 |
Identification of adverse reactions to new drugs. II--How were 18 important adverse reactions discovered and with what delays?
Topics: Chloramphenicol; Clioquinol; Contraceptives, Oral; Diethylstilbestrol; Drug and Narcotic Control; Dr | 1983 |
[Drug-induced liver damage; new aspects on its mechanism].
Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Chlorpromazine; Contraceptives, Oral; Drug-Re | 1980 |
[Effects of drugs on the liver. A review illustrated with 3 clinical cases].
Topics: Acetaminophen; Adult; Aged; Androgens; Chemical and Drug Induced Liver Injury; Denmark; Disulfiram; | 1994 |
Drug associated hepatic reactions in New Zealand: 21 years experience.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; Amoxicillin; A | 1996 |
Hepatic reactions to drugs.
Topics: Acetaminophen; Adenoma; Adult; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur | 1979 |
Drug reactions and interactions in the patient undergoing surgery.
Topics: Anesthetics; Barbiturates; Butyrylcholinesterase; Drug Interactions; Drug-Related Side Effects and A | 1979 |
Drug-induced liver injury.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug-Related | 1978 |
[Drug-induced icterus].
Topics: Anticoagulants; Anticonvulsants; Cathartics; Contraceptives, Oral; Drug-Related Side Effects and Adv | 1976 |
Liver disease caused by medicinal agents.
Topics: Adrenal Cortex Hormones; Analgesics; Chemical and Drug Induced Liver Injury; Cholestasis; Contracept | 1975 |
The immunological basis of adverse drug reactions. A report on a symposium held in Liverpool on 6th April 1988.
Topics: Animals; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug-Related Side Effects an | 1988 |
Guidelines for diagnosis of therapeutic drug-induced liver injury in liver biopsies.
Topics: Anabolic Agents; Biopsy; Cathartics; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholest | 1974 |
[Drug-induced damage of the liver].
Topics: Anesthesia, General; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse R | 1973 |
New Zealand Committee on Adverse Drug Reactions. Eighth annual report.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Anti-Ba | 1973 |
New Zealand Committee on Adverse Drug Reactions: Ninth Annual Report 1974.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Aged; Antineoplastic Agents; Drug Interactions; Drug | 1974 |
[Drug-induced hepatopathies].
Topics: Adult; Age Factors; Bilirubin; Cell Membrane; Chemical and Drug Induced Liver Injury; Cholestasis; D | 1974 |
[Results of monitoring of adverse drug effects in various European countries in the years 1967-1969].
Topics: Aerosols; Appetite Depressants; Chloramphenicol; Contraceptives, Oral; Czechoslovakia; Dextrans; Dru | 1970 |