Page last updated: 2024-10-28

haloperidol and Rhabdomyolysis

haloperidol has been researched along with Rhabdomyolysis in 17 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Rhabdomyolysis: Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.

Research Excerpts

ExcerptRelevanceReference
"A 6-year-old severely handicapped boy with haloperidol-induced mild rhabdomyolysis without neuroleptic malignant syndrome is reported."8.80Haloperidol-induced rhabdomyolysis without neuroleptic malignant syndrome in a handicapped child. ( Abe, T; Oda, Y; Ozawa, K; Watanabe, T; Yoshikawa, H, 2000)
"BACKGROUND Rhabdomyolysis is a condition in which intracellular components are released into the blood and urine."5.72A Case of Exacerbation of Haloperidol-Induced Rhabdomyolysis Following the Onset of COVID-19. ( Hirose, N; Inoue, J; Ishii, J; Koshioka, S; Kunishima, H; Kurata, T; Matsuura, M; Nagumo, F; Sada, Y; Samura, M; Takada, K; Tanikawa, K; Uchida, M, 2022)
"Cocaine-related rhabdomyolysis has a high mortality."5.29Rhabdomyolysis and hyperthermia after cocaine abuse: a variant of the neuroleptic malignant syndrome? ( Daras, M; Kakkouras, L; Koppel, BS; Tuchman, AJ, 1995)
"This case comes into the so-called neuroleptic malignant syndrome which can rarely arise in patients treated with antipsycotic agents and which causes high mortality, particularly when there are rhabdomyolysis and acute renal failure."5.29[Rhabdomyolysis and acute renal failure caused by haloperidol-decanoate (neuroleptic malignant syndrome)]. ( Benati, F; Cesario, V; Lazzarin, M, 1996)
"A 6-year-old severely handicapped boy with haloperidol-induced mild rhabdomyolysis without neuroleptic malignant syndrome is reported."4.80Haloperidol-induced rhabdomyolysis without neuroleptic malignant syndrome in a handicapped child. ( Abe, T; Oda, Y; Ozawa, K; Watanabe, T; Yoshikawa, H, 2000)
" Following initial improvement, she developed delayed rhabdomyolysis then haloperidol-induced neuroleptic malignant syndrome, which was treated with a total of 50 mg."3.78Ecstacy-induced delayed rhabdomyolysis and neuroleptic malignant syndrome in a patient with a novel variant in the ryanodine receptor type 1 gene. ( Hawryluck, LA; Kraeva, N; Riazi, S; Russell, T; Steel, AC, 2012)
"After receiving 90 mg of haloperidol and 100 mg of chlorpromazine hydrochloride within 25 hours, a 29-year-old man was found to have neuroleptic malignant syndrome (NMS), characterized by the acute onset of hyperpyrexia, extreme muscular rigidity, autonomic instability, and coma."3.67Neuroleptic malignant syndrome and dopaminergic blockade. ( Hashimoto, F; Jeffery, WH; Sherman, CB, 1984)
"BACKGROUND Rhabdomyolysis is a condition in which intracellular components are released into the blood and urine."1.72A Case of Exacerbation of Haloperidol-Induced Rhabdomyolysis Following the Onset of COVID-19. ( Hirose, N; Inoue, J; Ishii, J; Koshioka, S; Kunishima, H; Kurata, T; Matsuura, M; Nagumo, F; Sada, Y; Samura, M; Takada, K; Tanikawa, K; Uchida, M, 2022)
"We report a case of severe neuroleptic malignant syndrome with hyperthermia, rhabdomyolysis and hepatic failure where we applied endovascular cooling in order to reverse hyperthermia."1.35Endovascular cooling in a patient with neuroleptic malignant syndrome. ( Diedler, J; Mellado, P; Veltkamp, R, 2008)
"Cocaine-related rhabdomyolysis has a high mortality."1.29Rhabdomyolysis and hyperthermia after cocaine abuse: a variant of the neuroleptic malignant syndrome? ( Daras, M; Kakkouras, L; Koppel, BS; Tuchman, AJ, 1995)
"This case comes into the so-called neuroleptic malignant syndrome which can rarely arise in patients treated with antipsycotic agents and which causes high mortality, particularly when there are rhabdomyolysis and acute renal failure."1.29[Rhabdomyolysis and acute renal failure caused by haloperidol-decanoate (neuroleptic malignant syndrome)]. ( Benati, F; Cesario, V; Lazzarin, M, 1996)
"Rhabdomyolysis is a rarely reported complication of antipsychotic drug-induced dystonia."1.27Rhabdomyolysis due to acute dystonic reaction to antipsychotic drugs. ( Cavanaugh, JJ; Finlayson, RE, 1984)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19903 (17.65)18.7374
1990's7 (41.18)18.2507
2000's2 (11.76)29.6817
2010's3 (17.65)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Takada, K1
Sada, Y1
Samura, M1
Matsuura, M1
Hirose, N1
Kurata, T1
Nagumo, F1
Ishii, J1
Koshioka, S1
Uchida, M1
Inoue, J1
Tanikawa, K1
Kunishima, H1
Kajani, R1
Apramian, A1
Vega, A1
Ubhayakar, N1
Xu, P1
Liu, A1
Wystub, N1
Heymel, S1
Fritzenwanger, M1
Schulze, PC1
Pfeifer, R1
Kamijo, Y1
Russell, T1
Riazi, S1
Kraeva, N1
Steel, AC1
Hawryluck, LA1
Diedler, J1
Mellado, P1
Veltkamp, R1
Yasukawa, M1
Hatakeyama, Y1
Yasukawa, K1
Chiba, S1
Suzuki, T1
Takami, T1
Hashimoto, F1
Sherman, CB1
Jeffery, WH1
Cavanaugh, JJ1
Finlayson, RE1
Daras, M1
Kakkouras, L1
Tuchman, AJ1
Koppel, BS1
Marsh, SJ1
Dolson, GM1
Girard, T1
Samet, S1
Bianchi-Fior, P1
Gasnault, J1
Brivet, F1
Korzets, Z1
Zelter, E1
Bernheim, J1
Lazzarin, M1
Benati, F1
Cesario, V1
Seki, Y1
Takahashi, H1
Aizawa, Y1
Yoshikawa, H1
Watanabe, T1
Abe, T1
Oda, Y1
Ozawa, K1
Soejima, A1
Suzuki, M1
Nagasawa, T1

Reviews

3 reviews available for haloperidol and Rhabdomyolysis

ArticleYear
[Dangerous drugs: products containing synthetic chemicals].
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Volume: 74, Issue:2

    Topics: Alkaloids; Antipsychotic Agents; Cannabinoids; Central Nervous System Diseases; Consciousness Disord

2016
Haloperidol-induced rhabdomyolysis without neuroleptic malignant syndrome in a handicapped child.
    Brain & development, 2000, Volume: 22, Issue:4

    Topics: Anti-Dyskinesia Agents; Child; Disabled Persons; Haloperidol; Humans; Male; Movement Disorders; Neur

2000
[Rhabdomyolysis].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:6

    Topics: Acute Kidney Injury; Adult; Chlorpromazine; Female; Haloperidol; Humans; Myoglobin; Myoglobinuria; R

1991

Other Studies

14 other studies available for haloperidol and Rhabdomyolysis

ArticleYear
A Case of Exacerbation of Haloperidol-Induced Rhabdomyolysis Following the Onset of COVID-19.
    The American journal of case reports, 2022, Jun-20, Volume: 23

    Topics: Acute Kidney Injury; COVID-19; Haloperidol; Hematuria; Humans; Male; Middle Aged; Rhabdomyolysis

2022
Neuroleptic malignant syndrome in a COVID-19 patient.
    Brain, behavior, and immunity, 2020, Volume: 88

    Topics: Acute Kidney Injury; Antipsychotic Agents; Betacoronavirus; Bromocriptine; C-Reactive Protein; Coron

2020
[Prolonged neuroleptic malignant syndrome after Haloperidol injection].
    Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2018, Volume: 113, Issue:3

    Topics: Antipsychotic Agents; Dantrolene; Haloperidol; Humans; Male; Middle Aged; Neuroleptic Malignant Synd

2018
Ecstacy-induced delayed rhabdomyolysis and neuroleptic malignant syndrome in a patient with a novel variant in the ryanodine receptor type 1 gene.
    Anaesthesia, 2012, Volume: 67, Issue:9

    Topics: Anesthetics, Inhalation; Antipsychotic Agents; Body Temperature; Caffeine; Central Nervous System St

2012
Endovascular cooling in a patient with neuroleptic malignant syndrome.
    Journal of the neurological sciences, 2008, Jan-15, Volume: 264, Issue:1-2

    Topics: Antipsychotic Agents; Catheters, Indwelling; Creatine Kinase; Drug Synergism; Female; Fever; Haloper

2008
[Neuroleptic malignant syndrome with myoglobinuria].
    Masui. The Japanese journal of anesthesiology, 1983, Volume: 32, Issue:7

    Topics: Basal Ganglia Diseases; Female; Haloperidol; Humans; Middle Aged; Myoglobinuria; Rhabdomyolysis; Sch

1983
Neuroleptic malignant syndrome and dopaminergic blockade.
    Archives of internal medicine, 1984, Volume: 144, Issue:3

    Topics: Adult; Chlorpromazine; Dopamine; Haloperidol; Humans; Male; Muscular Diseases; Receptors, Dopamine;

1984
Rhabdomyolysis due to acute dystonic reaction to antipsychotic drugs.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:8

    Topics: Acute Disease; Adult; Dystonia; Haloperidol; Humans; Male; Muscles; Myoglobinuria; Psychotic Disorde

1984
Rhabdomyolysis and hyperthermia after cocaine abuse: a variant of the neuroleptic malignant syndrome?
    Acta neurologica Scandinavica, 1995, Volume: 92, Issue:2

    Topics: Adult; Antipsychotic Agents; Brain; Cell Death; Cocaine; Diagnosis, Differential; Diazepam; Female;

1995
Rhabdomyolysis and acute renal failure during high-dose haloperidol therapy.
    Renal failure, 1995, Volume: 17, Issue:4

    Topics: Acute Kidney Injury; Adult; Antipsychotic Agents; Haloperidol; Humans; Male; Neuroleptic Malignant S

1995
[Haloperidol, a new cause of rhabdomyolysis, in the absence of neuroleptic malignant syndrome].
    Presse medicale (Paris, France : 1983), 1994, Oct-22, Volume: 23, Issue:32

    Topics: Aged; Haloperidol; Humans; Male; Rhabdomyolysis

1994
Acute renal failure in the setting of the neuroleptic malignant syndrome.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11, Issue:5

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Antipsychotic Agents; Dopamine Antagonists; Female; Ha

1996
[Rhabdomyolysis and acute renal failure caused by haloperidol-decanoate (neuroleptic malignant syndrome)].
    Recenti progressi in medicina, 1996, Volume: 87, Issue:9

    Topics: Acute Kidney Injury; Antipsychotic Agents; Haloperidol; Humans; Male; Middle Aged; Neuroleptic Malig

1996
[Hemostatic evaluation of a patient with haloperidol-induced neuroleptic malignant syndrome associated with disseminated intravascular coagulation].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:5

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Antipsychotic Agents; Blood Coagulation; Blood Coagula

1998