Page last updated: 2024-10-28

haloperidol and Obsessive-Compulsive Disorder

haloperidol has been researched along with Obsessive-Compulsive Disorder in 50 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Obsessive-Compulsive Disorder: An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.

Research Excerpts

ExcerptRelevanceReference
"Nine patients with trichotillomania were treated with haloperidol."9.09The potential role of haloperidol in the treatment of trichotillomania. ( Farvolden, P; Mancini, C; Oakman, JM; Van Ameringen, M, 1999)
"To determine the efficacy of adding haloperidol to the treatment of patients with obsessive-compulsive disorder (OCD), with or without a comorbid chronic tic disorder, who were refractory to adequate treatment with the serotonin-uptake inhibitor fluvoxamine alone."9.07Haloperidol addition in fluvoxamine-refractory obsessive-compulsive disorder. A double-blind, placebo-controlled study in patients with and without tics. ( Goodman, WK; Heninger, GR; Leckman, JF; Lee, NC; McDougle, CJ; Price, LH, 1994)
" In the present study, we examined the effect of perospirone on marble-burying behavior, which has been considered an animal model of obsessive-compulsive disorder (OCD), compared with the effects of other antipsychotics such as haloperidol and risperidone."7.73Perospirone, a novel antipsychotic drug, inhibits marble-burying behavior via 5-HT1A receptor in mice: implications for obsessive-compulsive disorder. ( Egashira, N; Fujiwara, M; Harada, S; Iwasaki, K; Matsushita, M; Mishima, K; Nishimura, R; Okuno, R, 2005)
"Erythrocyte and plasma choline parameters were compared in children (n = 63), aged 6-18 years, suffering from Tourette Syndrome (TS), their parents (n = 57), their unaffected siblings (n = 38), and an adult control group (n = 57)."7.68Controlled study of erythrocyte choline in Tourette syndrome. ( Hanin, I; Kopp, U; Sallee, FR, 1992)
"Nine patients with trichotillomania were treated with haloperidol."5.09The potential role of haloperidol in the treatment of trichotillomania. ( Farvolden, P; Mancini, C; Oakman, JM; Van Ameringen, M, 1999)
"To determine the efficacy of adding haloperidol to the treatment of patients with obsessive-compulsive disorder (OCD), with or without a comorbid chronic tic disorder, who were refractory to adequate treatment with the serotonin-uptake inhibitor fluvoxamine alone."5.07Haloperidol addition in fluvoxamine-refractory obsessive-compulsive disorder. A double-blind, placebo-controlled study in patients with and without tics. ( Goodman, WK; Heninger, GR; Leckman, JF; Lee, NC; McDougle, CJ; Price, LH, 1994)
" In the present study, we examined the effect of perospirone on marble-burying behavior, which has been considered an animal model of obsessive-compulsive disorder (OCD), compared with the effects of other antipsychotics such as haloperidol and risperidone."3.73Perospirone, a novel antipsychotic drug, inhibits marble-burying behavior via 5-HT1A receptor in mice: implications for obsessive-compulsive disorder. ( Egashira, N; Fujiwara, M; Harada, S; Iwasaki, K; Matsushita, M; Mishima, K; Nishimura, R; Okuno, R, 2005)
"Erythrocyte and plasma choline parameters were compared in children (n = 63), aged 6-18 years, suffering from Tourette Syndrome (TS), their parents (n = 57), their unaffected siblings (n = 38), and an adult control group (n = 57)."3.68Controlled study of erythrocyte choline in Tourette syndrome. ( Hanin, I; Kopp, U; Sallee, FR, 1992)
"Clomipramine hydrochloride, a tricyclic antidepressant that blocks serotonin and norepinephrine reuptake, is indicated in the treatment of Obsessive-Compulsive Disorder."3.68Tourette's syndrome and treatment with clomipramine hydrochloride. ( Donahoe, DH; Fortune, T; Llorena, R; Meador, M, 1991)
"Children with Sydenham's chorea and PANDAS (Pediatric autoimmune neuropsychiatric disorders associated with streptococcal throat infections) share an array of neuropsychiatric symptoms and distinguishing one from the other, especially at onset can prove challenging."2.42Distinguishing PANDAS from Sydenham's chorea: case report and review of the literature. ( Schoeman, JF; van Toorn, R; Weyers, HH, 2004)
"The increasing recognition of Tourette's syndrome is probably responsible for the broadening range of symptom severities seen in clinic patients."2.39Considerations of natural history and pathophysiology in the psychopharmacology of Tourette's syndrome. ( Peterson, BS, 1996)
"Sydenham's chorea is a symptom of rheumatic fever and results from an autoimmune attack on the CNS."2.39Neuropsychiatric aspects of Sydenham's chorea: a comprehensive review. ( Moore, DP, 1996)
"fluoxetine) anxiolytics inhibit marble burying."1.33A combined marble burying-locomotor activity test in mice: a practical screening test with sensitivity to different classes of anxiolytics and antidepressants. ( Kolb, Y; Nicolas, LB; Prinssen, EP, 2006)
"A clear double dissociation of Wisconsin Card Sorting Test and Gambling Task performances was found, with SKZ patients performing the Wisconsin Card Sorting test significantly worse than OCD patients and control subjects and OCD patients performing the Gambling Task significantly worse than SKZ and control subjects."1.32Basal-corticofrontal circuits in schizophrenia and obsessive-compulsive disorder: a controlled, double dissociation study. ( Angelone, SM; Bassi, T; Bellodi, L; Cavallaro, R; Cavedini, P; Mistretta, P; Ubbiali, A, 2003)
" Chronic administration of the selective serotonin re-uptake inhibitors fluoxetine and clomipramine (CMI) at 5 mg/kg per day and fluvoxamine at 10 mg/kg twice a day significantly decreased schedule-induced polydipsia (SIP) on day 15 and throughout the remainder of the study compared to control rats."1.29Selective serotonin re-uptake inhibitors decrease schedule-induced polydipsia in rats: a potential model for obsessive compulsive disorder. ( Corbett, R; Cornfeldt, M; Dunn, RW; Smith, C; Szewczak, M; Woods, A, 1993)
" Patients were treated with risperidone in two different dosage groups (3 mg and 8 mg) and haloperidol (10-20 mg) and compared with eight healthy control subjects."1.29Striatal dopamine-2 receptor occupancy in psychotic patients treated with risperidone. ( Asenbaum, S; Brücke, T; Gössler, R; Kasper, S; Küfferle, B; Podreka, I; Tauscher, J; Topitz-Schratzberger, A; Vesely, C, 1996)
"When treated with clomipramine 100 mg daily (plasma level 85 ng/mL), obsessive-compulsive symptoms but not the hallucinations improved significantly, and racing thoughts and grandiosity developed later."1.29Differential response of psychotic and obsessive symptoms to risperidone in an adolescent. ( Dryden-Edwards, RC; Reiss, AL, 1996)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199013 (26.00)18.7374
1990's20 (40.00)18.2507
2000's9 (18.00)29.6817
2010's7 (14.00)24.3611
2020's1 (2.00)2.80

Authors

AuthorsStudies
Ghanbarzehi, A1
Sepehrinezhad, A1
Hashemi, N1
Karimi, M1
Shahbazi, A1
Rask, O1
Suneson, K1
Holmström, E1
Bäckström, B1
Johansson, BA1
Arikawa, A1
Mito, H1
Motoyama, M1
Yamanishi, K1
Hayashida, K1
Maebayashi, K1
Matsunaga, H1
Danovich, L1
Weinreb, O1
Youdim, MB1
Silver, H1
Nakamae, T1
Ulhaq, I1
Abba-Aji, A1
Schmidt, TT1
Rea, E1
Shababi-Klein, J1
Panagis, G1
Winter, C1
Kreiss, DS1
Coffman, CF1
Fiacco, NR1
Granger, JC1
Helton, BM1
Jackson, JC1
Kim, LV1
Mistry, RS1
Mizer, TM1
Palmer, LV1
Vacca, JA1
Winkler, SS1
Zimmer, BA1
Joel, D1
Doljansky, J1
Cavallaro, R1
Cavedini, P1
Mistretta, P1
Bassi, T1
Angelone, SM1
Ubbiali, A1
Bellodi, L1
SVENDSEN, BB1
WILLADSEN, J1
Kano, Y1
van Toorn, R1
Weyers, HH1
Schoeman, JF1
Li, X1
May, RS1
Tolbert, LC1
Jackson, WT1
Flournoy, JM1
Baxter, LR1
Machida, N1
Shiotsuka, S1
Semba, J1
Matsushita, M1
Egashira, N1
Harada, S1
Okuno, R1
Mishima, K1
Iwasaki, K1
Nishimura, R1
Fujiwara, M1
Bloch, MH1
Landeros-Weisenberger, A1
Kelmendi, B1
Coric, V1
Bracken, MB1
Leckman, JF3
Nicolas, LB1
Kolb, Y1
Prinssen, EP1
Cohen, DJ1
McDougle, CJ3
Goodman, WK3
Price, LH2
Woods, A1
Smith, C1
Szewczak, M1
Dunn, RW1
Cornfeldt, M1
Corbett, R1
Budman, CL1
Sherling, M1
Bruun, RD1
LaPorta, LD1
Lee, NC1
Heninger, GR1
Escobar, R1
Bernardo, M1
Rickards, H1
Peterson, BS1
Küfferle, B1
Brücke, T1
Topitz-Schratzberger, A1
Tauscher, J1
Gössler, R1
Vesely, C1
Asenbaum, S1
Podreka, I1
Kasper, S1
Dryden-Edwards, RC1
Reiss, AL1
Leonard, HL1
Moore, DP1
Benazzi, F1
Van Ameringen, M1
Mancini, C1
Oakman, JM1
Farvolden, P1
Gelenberg, AJ1
Mandel, MR1
Sallee, FR1
Kopp, U1
Hanin, I1
Stárková, L2
Wiedermann, J1
Donahoe, DH1
Meador, M1
Fortune, T1
Llorena, R1
Matthews, P1
Quinn, D1
Marcoux, GS1
Falkenberg, K1
Mrna, B1
Caine, ED1
McBride, MC1
Chiverton, P1
Bamford, KA1
Rediess, S1
Shiao, J1
Ananth, J1
Baer, L1
Minichiello, WE1
Jenike, MA1
Carman, JS1
Woodrow, KM1
O'Regan, JB2
Hussain, MZ1
Ahad, A1
Greger, J1
Glitschka, A1
Müller, K1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Quetiapine Augmentation Versus Clomipramine Augmentation of Selective Serotonin Reuptake Inhibitors for Obsessive-compulsive Disorder Patients That do Not Respond to a SSRI Trial: a Randomized Open-trial.[NCT00564564]Phase 421 participants (Actual)Interventional2006-01-31Completed
Ketamine Treatment for Pediatric-Refractory Obsessive-Compulsive Disorder (OCD)[NCT02422290]Phase 1/Phase 25 participants (Actual)Interventional2015-03-31Completed
An Open-Label Trial of Epidiolex in the Treatment of Obsessive Compulsive Disorder and Related Disorders: Proof of Concept Study[NCT04978428]Phase 215 participants (Anticipated)Interventional2022-04-14Recruiting
Open Label Study for the Use of Transcranial Ultrasound Treatment of Obsessive-Compulsive Disorder[NCT04775875]30 participants (Anticipated)Interventional2020-12-01Enrolling by invitation
[NCT00004325]200 participants Observational1988-12-31Completed
Initial Evaluation of Efficacy and Adverse Events of Single Lesions in Bilateral Ventral-capsular and Ventral Capsulotomy-striatal by Linear Accelerator Radiosurgery in Severe and Refractory Obsessive-compulsive Disorder[NCT02500888]10 participants (Anticipated)Interventional2015-06-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Children's Yale-Brown Obsessive Compulsive Scale (CY-BOCS)

The CY-BOCS is a semi-structured measure of OCD severity with excellent inter-rater reliability, internal consistency, and test-retest reliability. It is validated in those starting at age 7 and used in studies up to age 20. The CYBOCS differs from the adult YBOCS only in its use of simpler language. The CY-BOCS consists of 10 items which are summed up to derive the total CY-BOCS score. The total score ranges from 0-40 with higher scores indicating greater severity of OCD symptoms. (NCT02422290)
Timeframe: Screening, Baseline, Day 7, Day 17, 3-Month; Baseline and Day 14 pre-specified to be reported

Interventionscore on a scale (Mean)
CY-BOCS BaselineCY-BOCS Day 14
Ketamine Treatment Group29.0026.20

Clinical Global Impressions - Severity Scale (CGI-S)

The CGI-S is a clinician rated 7-point rating scale for the severity of a participant's illness relative to the clinician's experience of working with this particular population. The score ranges from 1-7 with higher scores indicating greater illness severity. (NCT02422290)
Timeframe: Screening, Baseline, Day 7, Day 17, 3-Month; Baseline and Day 14 pre-specified to be reported

Interventionscore on a scale (Mean)
CGI-S BaselineCGI-S Day 14
Ketamine Treatment Group5.805.00

OCD Visual Analogue Scale (OCD-VAS)

"The OCD-VAS is a one-item unipolar scale to assess OCD symptoms over a rapid time frame (No obsessions to Constant obsessions). The scale ranges from 0-10 with higher scores indicating higher presence of obsessions." (NCT02422290)
Timeframe: Screening, Baseline, Day 1-14, 3-Month; Baseline and Day 14 pre-specified to be reported

Interventionscore on a scale (Mean)
OCD-VAS BaselineOCD-VAS Day 14
Ketamine Treatment Group5.005.00

Yale-Brown Obsessive Compulsive Challenge Scale (Y-BOCCS)

"The Y-BOCCS is self-report scale which assesses OCD symptoms on a 5-point likert scale (None to Extreme). It consists of 10 items which are summed up to derive the total Y-BOCCS score. The total score ranges from 0-40 with higher scores indicating higher prevalence of OCD symptoms." (NCT02422290)
Timeframe: Screening, Baseline, Day 1-14, 3-Month; Baseline and Day 14 pre-specified to be reported

Interventionscore on a scale (Mean)
Y-BOCCS BaselineY-BOCCS Day 14
Ketamine Treatment Group18.2516.50

Reviews

14 reviews available for haloperidol and Obsessive-Compulsive Disorder

ArticleYear
[Diversity of obsessive-compulsive disorder and pharmacotherapy associated with obsessive-compulsive spectrum disorders].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2011, Volume: 113, Issue:10

    Topics: Antipsychotic Agents; Autistic Disorder; Body Dysmorphic Disorders; Clomipramine; Comorbidity; Disru

2011
[Chronic tic disorders--chronic mortor or vocal tic disorders and de la Tourette's syndrome].
    Ryoikibetsu shokogun shirizu, 2003, Issue:40

    Topics: Adolescent; Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous Sy

2003
Distinguishing PANDAS from Sydenham's chorea: case report and review of the literature.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2004, Volume: 8, Issue:4

    Topics: Child; Chorea; Diagnosis, Differential; Haloperidol; Humans; Long-Term Care; Male; Neurologic Examin

2004
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder.
    Molecular psychiatry, 2006, Volume: 11, Issue:7

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Comorbidity; Depressive

2006
Recent advances in Gilles de la Tourette syndrome: implications for clinical practice and future research.
    Psychiatric developments, 1983,Autumn, Volume: 1, Issue:3

    Topics: Adolescent; Age Factors; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Compulsive

1983
Dopamine antagonists in tic-related and psychotic spectrum obsessive compulsive disorder.
    The Journal of clinical psychiatry, 1994, Volume: 55 Suppl

    Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Clomipramine; Clozapine; Dopamine Antagonists

1994
Tics and fits. The current status of Gilles de la Tourette syndrome and its relationship with epilepsy.
    Seizure, 1995, Volume: 4, Issue:4

    Topics: Antipsychotic Agents; Diagnosis, Differential; Epilepsies, Partial; Haloperidol; Humans; Obsessive-C

1995
Considerations of natural history and pathophysiology in the psychopharmacology of Tourette's syndrome.
    The Journal of clinical psychiatry, 1996, Volume: 57 Suppl 9

    Topics: Adolescent; Adult; Age of Onset; Antipsychotic Agents; Child; Clozapine; Disease Progression; Diseas

1996
Update on pharmacologic management of OCD: agents and augmentation.
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 12

    Topics: Clinical Trials as Topic; Clozapine; Dopamine Agents; Drug Therapy, Combination; Female; Fenfluramin

1997
New developments in the treatment of obsessive-compulsive disorder.
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 14

    Topics: Adjuvants, Immunologic; Adolescent; Adult; Age Factors; Age of Onset; Antidepressive Agents, Second-

1997
Neuropsychiatric aspects of Sydenham's chorea: a comprehensive review.
    The Journal of clinical psychiatry, 1996, Volume: 57, Issue:9

    Topics: Adult; Autoimmune Diseases; Chorea; Comorbidity; Haloperidol; Humans; Mental Disorders; Obsessive-Co

1996
Obsessive-compulsive disorder: diagnosis and treatment.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 18

    Topics: Anxiety Disorders; Behavior Therapy; Clinical Trials as Topic; Combined Modality Therapy; Comorbidit

1999
Clomipramine: an antiobsessive drug.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1986, Volume: 31, Issue:3

    Topics: Anxiety; Behavior Therapy; Clinical Trials as Topic; Clomipramine; Compulsive Behavior; Depressive D

1986
Gilles de la Tourette's disease--a review.
    The American journal of psychiatry, 1974, Volume: 131, Issue:9

    Topics: Adolescent; Age Factors; Child; Child, Preschool; Corpus Striatum; Diagnosis, Differential; Female;

1974

Trials

4 trials available for haloperidol and Obsessive-Compulsive Disorder

ArticleYear
Risperidone and haloperidol augmentation of serotonin reuptake inhibitors in refractory obsessive-compulsive disorder: a crossover study.
    The Journal of clinical psychiatry, 2005, Volume: 66, Issue:6

    Topics: Adult; Antipsychotic Agents; Cognition Disorders; Cross-Over Studies; Double-Blind Method; Drug Ther

2005
Haloperidol addition in fluvoxamine-refractory obsessive-compulsive disorder. A double-blind, placebo-controlled study in patients with and without tics.
    Archives of general psychiatry, 1994, Volume: 51, Issue:4

    Topics: Adolescent; Adult; Age of Onset; Behavior Therapy; Comorbidity; Double-Blind Method; Drug Therapy, C

1994
The potential role of haloperidol in the treatment of trichotillomania.
    Journal of affective disorders, 1999, Volume: 56, Issue:2-3

    Topics: Adult; Anti-Dyskinesia Agents; Female; Haloperidol; Humans; Male; Middle Aged; Obsessive-Compulsive

1999
Clomipramine: an antiobsessive drug.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1986, Volume: 31, Issue:3

    Topics: Anxiety; Behavior Therapy; Clinical Trials as Topic; Clomipramine; Compulsive Behavior; Depressive D

1986

Other Studies

33 other studies available for haloperidol and Obsessive-Compulsive Disorder

ArticleYear
Disclosing common biological signatures and predicting new therapeutic targets in schizophrenia and obsessive-compulsive disorder by integrated bioinformatics analysis.
    BMC psychiatry, 2023, 01-14, Volume: 23, Issue:1

    Topics: Haloperidol; Humans; MicroRNAs; Obsessive-Compulsive Disorder; Psychotic Disorders; Schizophrenia; S

2023
Electroconvulsive therapy for manic state with mixed and psychotic features in a teenager with bipolar disorder and comorbid episodic obsessive-compulsive disorder: a case report.
    Journal of medical case reports, 2017, Dec-12, Volume: 11, Issue:1

    Topics: Adolescent; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Comorbidity; Electroconvulsive

2017
[A Case with Multiple Comorbidities of Obsessive-Compulsive and Related Disorders].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2015, Volume: 117, Issue:11

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Body Dysmorphic Disorders; Clonazepam; Combined Modality

2015
The involvement of GABA(A) receptor in the molecular mechanisms of combined selective serotonin reuptake inhibitor-antipsychotic treatment.
    The international journal of neuropsychopharmacology, 2011, Volume: 14, Issue:2

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Cells, Cultured; Clozapine; Dopamine; Drug The

2011
Haloperidol induced obsessive compulsive symptom (OCS) in a patient with learning disability and bipolar affective disorder.
    BMJ case reports, 2012, Mar-08, Volume: 2012

    Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Diagnosis, Differential; Haloperidol; Humans; Learnin

2012
Enhanced reward-facilitating effects of d-amphetamine in rats in the quinpirole model of obsessive-compulsive disorder.
    The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:5

    Topics: Analysis of Variance; Animals; Central Nervous System Stimulants; Conditioning, Operant; Dextroamphe

2013
Ritualistic chewing behavior induced by mCPP in the rat is an animal model of obsessive compulsive disorder.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 104

    Topics: Animals; Behavior, Animal; Clomipramine; Diazepam; Disease Models, Animal; Dopamine Antagonists; Flu

2013
Selective alleviation of compulsive lever-pressing in rats by D1, but not D2, blockade: possible implications for the involvement of D1 receptors in obsessive-compulsive disorder.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:1

    Topics: Animals; Benzazepines; Compulsive Behavior; Conditioning, Operant; Cues; Dopamine Antagonists; Dopam

2003
Basal-corticofrontal circuits in schizophrenia and obsessive-compulsive disorder: a controlled, double dissociation study.
    Biological psychiatry, 2003, Aug-15, Volume: 54, Issue:4

    Topics: Adult; Antipsychotic Agents; Basal Ganglia; Case-Control Studies; Clozapine; Corpus Striatum; Dissoc

2003
THE USE OF HALOPERIDOL (SERENASE (R)) IN CHLORPROTIXEN RESISTANT PATIENTS.
    Acta psychiatrica Scandinavica, 1963, Volume: 39

    Topics: Accommodation, Ocular; Adolescent; Antisocial Personality Disorder; Bipolar Disorder; Chlorprothixen

1963
[Case of obsessive-compulsive disorder associated with neuroleptics-induced deficit syndrome (NIDS): successfully treated by discontinuation of neuroleptics followed by SSRI].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2005, Volume: 107, Issue:7

    Topics: Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Fluvoxamine; Haloperidol; Human

2005
Perospirone, a novel antipsychotic drug, inhibits marble-burying behavior via 5-HT1A receptor in mice: implications for obsessive-compulsive disorder.
    Journal of pharmacological sciences, 2005, Volume: 99, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Behavior, Animal; Disease Mod

2005
A combined marble burying-locomotor activity test in mice: a practical screening test with sensitivity to different classes of anxiolytics and antidepressants.
    European journal of pharmacology, 2006, Oct-10, Volume: 547, Issue:1-3

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Diazepa

2006
Selective serotonin re-uptake inhibitors decrease schedule-induced polydipsia in rats: a potential model for obsessive compulsive disorder.
    Psychopharmacology, 1993, Volume: 112, Issue:2-3

    Topics: Animals; Clomipramine; Conditioning, Operant; Desipramine; Diazepam; Disease Models, Animal; Drinkin

1993
Combined pharmacotherapy risk.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1995, Volume: 34, Issue:3

    Topics: Child; Drug Therapy, Combination; Haloperidol; Humans; Male; Obsessive-Compulsive Disorder; Paroxeti

1995
More on obsessive-compulsive symptoms and clozapine.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:7

    Topics: Adult; Clozapine; Haloperidol; Humans; Male; Obsessive-Compulsive Disorder; Schizophrenia; Schizophr

1994
Schizophrenia, obsessive-compulsive disorder, and Tourette's syndrome: a case of triple comorbidity.
    The Journal of neuropsychiatry and clinical neurosciences, 1993,Winter, Volume: 5, Issue:1

    Topics: Adult; Basal Ganglia Diseases; Brain; Clomipramine; Comorbidity; Female; Haloperidol; Humans; Obsess

1993
Striatal dopamine-2 receptor occupancy in psychotic patients treated with risperidone.
    Psychiatry research, 1996, Nov-25, Volume: 68, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Benzamides; Brain Mapping; Dopamin

1996
Differential response of psychotic and obsessive symptoms to risperidone in an adolescent.
    Journal of child and adolescent psychopharmacology, 1996,Summer, Volume: 6, Issue:2

    Topics: 1-Naphthylamine; Adolescent; Antidepressive Agents; Antipsychotic Agents; Clomipramine; Hallucinatio

1996
Urinary retention with sertraline, haloperidol, and clonazepam combination.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1998, Volume: 43, Issue:10

    Topics: Adult; Antipsychotic Agents; Clonazepam; Comorbidity; Constipation; Delusions; Drug Therapy, Combina

1998
Catatonic reactions to high-potency neuroleptic drugs.
    Archives of general psychiatry, 1977, Volume: 34, Issue:8

    Topics: Adolescent; Adult; Amantadine; Catatonia; Dose-Response Relationship, Drug; Female; Fluphenazine; Ha

1977
Controlled study of erythrocyte choline in Tourette syndrome.
    Biological psychiatry, 1992, Jun-15, Volume: 31, Issue:12

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Choline; Drug Therapy, Combination

1992
Our experience with incisive neuroleptic drugs in child psychiatry.
    Acta Universitatis Palackianae Olomucensis Facultatis Medicae, 1991, Volume: 131

    Topics: Antipsychotic Agents; Autistic Disorder; Child; Haloperidol; Humans; Mental Disorders; Obsessive-Com

1991
Tourette's syndrome and treatment with clomipramine hydrochloride.
    The West Virginia medical journal, 1991, Volume: 87, Issue:10

    Topics: Adult; Clomipramine; Drug Administration Schedule; Haloperidol; Humans; Male; Obsessive-Compulsive D

1991
Fluoxetine and neuroleptic synergistic effects.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1991, Volume: 30, Issue:1

    Topics: Adolescent; Chlorpromazine; Diseases in Twins; Drug Synergism; Fluoxetine; Haloperidol; Humans; Male

1991
Incisive neuroleptic drugs in child psychiatry.
    Activitas nervosa superior, 1989, Volume: 31, Issue:2

    Topics: Antipsychotic Agents; Child; Child Psychiatry; Haloperidol; Humans; Obsessive-Compulsive Disorder; P

1989
Tourette's syndrome in Monroe County school children.
    Neurology, 1988, Volume: 38, Issue:3

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Behavior; Child; Child, Preschool; Clonid

1988
Behavioral treatment in two cases of obsessive-compulsive disorder with concomitant bipolar affective disorder.
    The American journal of psychiatry, 1985, Volume: 142, Issue:3

    Topics: Adult; Behavior Therapy; Bipolar Disorder; Desipramine; Female; Haloperidol; Humans; Lithium; Male;

1985
Hyperdopaminergic states: a continuum.
    Lancet (London, England), 1972, Dec-09, Volume: 2, Issue:7789

    Topics: Dihydroxyphenylalanine; Haloperidol; Humans; Obsessive-Compulsive Disorder; Physostigmine; Tryptopha

1972
Treatment of obsessive-compulsive neurosis.
    Canadian Medical Association journal, 1970, Sep-26, Volume: 103, Issue:6

    Topics: Haloperidol; Humans; Obsessive-Compulsive Disorder; Tourette Syndrome

1970
Treatment of obsessive--compulsive neurosis with haloperidol.
    Canadian Medical Association journal, 1970, Jul-18, Volume: 103, Issue:2

    Topics: Haloperidol; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder

1970
Treatment of obsessive-compulsive neurosis.
    Canadian Medical Association journal, 1970, Sep-26, Volume: 103, Issue:6

    Topics: Amitriptyline; Chlordiazepoxide; Chlorprothixene; Haloperidol; Humans; Imipramine; Obsessive-Compuls

1970
[On the position of the butyrophenone derivative Haloperidol in psychiatric treatment].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1968, Volume: 20, Issue:7

    Topics: Adult; Aged; Bipolar Disorder; Catatonia; Child; Depression; Depressive Disorder, Major; Extrapyrami

1968