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haloperidol and Neurodegenerative Diseases

haloperidol has been researched along with Neurodegenerative Diseases in 5 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.

Research Excerpts

ExcerptRelevanceReference
"Schizophrenia is a neurodevelopmental disorder associated with persistent symptomatology, severe functional disability, and residual morbidity characteristic of neurodegenerative brain diseases."1.34Neuroprotection: a therapeutic strategy to prevent deterioration associated with schizophrenia. ( Jarskog, LF; Lieberman, JA; Perkins, DO, 2007)
"In the histopathology of Alzheimer's disease (AD) many signs of oxidative reactions can be found building the basis of the oxidative stress hypothesis of AD."1.30Vitamin E and other antioxidants in neuroprotection. ( Behl, C, 1999)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Górska, A1
Marszałł, M1
Sloderbach, A1
Lieberman, JA1
Perkins, DO1
Jarskog, LF1
Harvey, BH1
Joubert, C1
du Preez, JL1
Berk, M1
Colado, MI1
O'Shea, E1
Granados, R1
Esteban, B1
Martín, AB1
Green, AR1
Behl, C1

Reviews

1 review available for haloperidol and Neurodegenerative Diseases

ArticleYear
[The neurotoxicity of pyridinium metabolites of haloperidol].
    Postepy higieny i medycyny doswiadczalnej (Online), 2015, Oct-19, Volume: 69

    Topics: Antipsychotic Agents; Biotransformation; Brain; Delirium; Haloperidol; Humans; Nausea; Neurodegenera

2015

Other Studies

4 other studies available for haloperidol and Neurodegenerative Diseases

ArticleYear
Neuroprotection: a therapeutic strategy to prevent deterioration associated with schizophrenia.
    CNS spectrums, 2007, Volume: 12, Issue:3 Suppl 4

    Topics: Adolescent; Adult; Antipsychotic Agents; Atrophy; Benzodiazepines; Cerebral Cortex; Child; Cognition

2007
Effect of chronic N-acetyl cysteine administration on oxidative status in the presence and absence of induced oxidative stress in rat striatum.
    Neurochemical research, 2008, Volume: 33, Issue:3

    Topics: Acetylcysteine; Animals; Antipsychotic Agents; Dose-Response Relationship, Drug; Free Radical Scaven

2008
Studies on the role of dopamine in the degeneration of 5-HT nerve endings in the brain of Dark Agouti rats following 3,4-methylenedioxymethamphetamine (MDMA or 'ecstasy') administration.
    British journal of pharmacology, 1999, Volume: 126, Issue:4

    Topics: Animals; Body Temperature; Brain; Dopamine; Free Radicals; Haloperidol; Levodopa; Male; N-Methyl-3,4

1999
Vitamin E and other antioxidants in neuroprotection.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1999, Volume: 69, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Antipsychotic Agents; Estrogens; Female; Fre

1999