Page last updated: 2024-10-28

haloperidol and Necrosis

haloperidol has been researched along with Necrosis in 13 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Haloperidol, a dopamine receptor antagonist and sigma-receptor-active neuroleptic drug, is cytotoxic to primary hippocampal neurones, C6 glioma cells and NCB20 cells."3.69Haloperidol-induced cell death--mechanism and protection with vitamin E in vitro. ( Behl, C; Holsboer, F; Rupprecht, R; Skutella, T, 1995)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19908 (61.54)18.7374
1990's3 (23.08)18.2507
2000's1 (7.69)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hejna, P1
Ublová, M1
Voříšek, V1
Lombardi, G1
Varsaldi, F1
Miglio, G1
Papini, MG1
Battaglia, A1
Canonico, PL1
Behl, C1
Rupprecht, R1
Skutella, T1
Holsboer, F1
Kleeb, SR1
Xavier, JG1
Frussa-Filho, R1
Dagli, ML1
Hedeman, LS1
Sil, R1
Madej, JA1
Kapłońska, J1
Krajewska, B1
Liebhart, J1
Juźwiak, I1
Germanaud, J1
Pfau-Fandard, B1
Fleury, C1
Rousseau, A1
Browne, RM2
Friend, LA2
Erausquin, J1
Muruzábal, M1

Other Studies

13 other studies available for haloperidol and Necrosis

ArticleYear
Black esophagus: acute esophageal necrosis in fatal haloperidol intoxication.
    Journal of forensic sciences, 2013, Volume: 58, Issue:5

    Topics: Antipsychotic Agents; Chlorprothixene; Dibenzothiepins; Esophagus; Female; Forensic Pathology; Halop

2013
Cabergoline prevents necrotic neuronal death in an in vitro model of oxidative stress.
    European journal of pharmacology, 2002, Dec-20, Volume: 457, Issue:2-3

    Topics: Cabergoline; Cell Death; Cell Survival; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Recepto

2002
Haloperidol-induced cell death--mechanism and protection with vitamin E in vitro.
    Neuroreport, 1995, Dec-29, Volume: 7, Issue:1

    Topics: Animals; Antipsychotic Agents; Apoptosis; Cell Death; Cricetinae; Cricetulus; Dopamine Antagonists;

1995
Effect of haloperidol on the development of the solid Ehrlich tumor in mice.
    Life sciences, 1997, Volume: 60, Issue:4-5

    Topics: Analysis of Variance; Animals; Antipsychotic Agents; Carcinoma, Ehrlich Tumor; Haloperidol; Male; Mi

1997
Studies in experimental spinal cord trauma. 2. Comparison of treatment with steroids, low molecular weight dextran, and catecholamine blockade.
    Journal of neurosurgery, 1974, Volume: 40, Issue:1

    Topics: Animals; Dextrans; Disease Models, Animal; Dogs; Edema; Glucocorticoids; Haloperidol; Hypoxia; Methy

1974
[Morphological and functional changes in the bronchi caused by chemical substances used in the production of paints and lacquers as a pathogenic factor of occupational bronchial asthma. I. Morphological changes in the lungs of rats after long-term exposur
    Pneumonologia polska, 1983, Volume: 51, Issue:7

    Topics: Animals; Asthma; Bronchi; Epoxy Resins; Necrosis; Occupational Diseases; Paint; Rats; Rats, Inbred S

1983
[A chemical necrosis].
    Journal de toxicologie clinique et experimentale, 1992, Volume: 12, Issue:8

    Topics: Epoxy Resins; Female; Finger Injuries; Fingers; Humans; Middle Aged; Necrosis

1992
Acute hepatic failure after occupational exposure to 2-nitropropane.
    MMWR. Morbidity and mortality weekly report, 1985, Nov-01, Volume: 34, Issue:43

    Topics: Alanine Transaminase; Alkanes; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury;

1985
Leads from the MMWR. Acute hepatic failure after occupational exposure to 2-nitropropane.
    JAMA, 1985, Dec-27, Volume: 254, Issue:24

    Topics: Alanine Transaminase; Alkanes; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury;

1985
Acrylic resins.
    Food and cosmetics toxicology, 1971, Volume: 9, Issue:1

    Topics: Acrylates; Acrylic Resins; Animals; Anti-Infective Agents, Local; Asthma; Copper; Cyanides; Dental A

1971
An investigation into the irritant properties of some root filling materials.
    Archives of oral biology, 1968, Volume: 13, Issue:11

    Topics: Animals; Dental Amalgam; Dental Materials; Dental Restoration, Permanent; Epoxy Resins; Inflammation

1968
Tissue reactions to some root filling materials implanted in the bone of rabbits.
    Archives of oral biology, 1969, Volume: 14, Issue:6

    Topics: Animals; Bone and Bones; Dental Amalgam; Dental Materials; Epoxy Resins; Inflammation; Necrosis; Pol

1969
Tissue reaction to root canal fillings with plastic cements.
    Oral surgery, oral medicine, and oral pathology, 1970, Volume: 29, Issue:1

    Topics: Adhesiveness; Animals; Dental Cementum; Dental Materials; Dentin; Epoxy Resins; Inflammation; Necros

1970