Page last updated: 2024-10-28

haloperidol and Nausea

haloperidol has been researched along with Nausea in 55 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.

Research Excerpts

ExcerptRelevanceReference
"The purpose of the study was to compare efficacy and toxicity of olanzapine (OLN; a higher-cost drug) and haloperidol (HAL; a lower-cost drug) in the prevention of chemotherapy-induced nausea and vomiting (CINV) in patients who receive highly emetogenic chemotherapy (HEC)."9.30Randomized Phase II Trial to Compare the Efficacy of Haloperidol and Olanzapine in the Control of Chemotherapy-Induced Nausea and Vomiting in Nepal. ( Acharya, B; Dulal, S; Neupane, P; Paudel, BD; Poudyal, BS; Shah, A; Shilpakar, R; Wood, LA, 2019)
"Haloperidol as an adjunctive therapy is superior to placebo for acute gastroparesis symptoms."9.24Randomized Controlled Double-blind Trial Comparing Haloperidol Combined With Conventional Therapy to Conventional Therapy Alone in Patients With Symptomatic Gastroparesis. ( Cardenas-Turanzas, M; Chambers, KA; Chathampally, Y; Paniagua, L; Patel, S; Roldan, CJ, 2017)
"Haloperidol is used commonly for the control of nausea and vomiting (N/V) in palliative care patients, but there is very little evidence to support its use."9.14The efficacy of haloperidol in the management of nausea and vomiting in patients with cancer. ( Douglas, C; Gilshenan, K; Hardy, JR; O'Shea, A; Welch, L; White, C, 2010)
" This study compared ziprasidone with the conventional antipsychotic haloperidol in outpatients with stable schizophrenia."9.10A 28-week comparison of ziprasidone and haloperidol in outpatients with stable schizophrenia. ( Bäuml, J; Hirsch, SR; Kissling, W; O'Connor, R; Power, A, 2002)
"Tropisetron is a novel antiserotoninergic drug with potent and specific activity against cancer chemotherapy-induced emesis."9.07Tropisetron plus haloperidol to ameliorate nausea and vomiting associated with high-dose alkylating agent cancer chemotherapy. ( Bonadonna, G; Bregni, M; Di Nicola, M; Gianni, AM; Siena, S, 1991)
"The antiemetic effectiveness of haloperidol plus dexamethasone was compared with that of prochlorperazine plus dexamethasone in a prospective study of patients receiving chemotherapy for breast cancer."9.06A randomized comparison of haloperidol plus dexamethasone versus prochlorperazine plus dexamethasone in preventing nausea and vomiting in patients receiving chemotherapy for breast cancer. ( Carpenter, JT; Conolley, C; Lee, J; Silvey, L; Wheeler, RH, 1988)
"Sixty-two postoperative patients were admitted to a double-blind study to compare the therapeutic effectiveness of a single intramuscular injection of 1 mg of haloperidol with that of a placebo for the relief of vomiting and nausea following surgical procedures."9.04The use of haloperidol for treatment of postoperative nausea and vomiting--a double-blind placebo-controlled trial. ( Barton, MD; Cohen, PJ; Libonati, M, 1975)
"0 mg) of haloperidol with that of placebo for the relief of vomiting and nausea due to gastrointestinal disorders."9.04Haloperidol parenterally for treatment of vomiting and nausea from gastrointestinal disorders in a group of geriatric patients: double-blind, placebo-controlled study. ( Nagel, JD; Robbins, EL, 1975)
"To evaluate the efficacy and adverse events associated with the use of haloperidol for the treatment of nausea and vomiting in palliative care patients."8.91Haloperidol for the treatment of nausea and vomiting in palliative care patients. ( Dorman, S; Murray-Brown, F, 2015)
"The primary objective of the review was to evaluate the efficacy and adverse events associated with the use of haloperidol for the treatment of nausea and vomiting in palliative care patients."8.85Haloperidol for the treatment of nausea and vomiting in palliative care patients. ( Dorman, S; Perkins, P, 2009)
"Haloperidol (HL) has successfully been used for nausea and abdominal pain in emergency departments (EDs)."8.02Haloperidol Use in the Emergency Department for Gastrointestinal Symptoms: Nausea, Vomiting, and Abdominal Pain. ( Jehangir, A; Malik, Z; Parkman, HP; Repanshek, ZD; Reznick-Lipina, K; Shahsavari, D; Weiner, M, 2021)
" From October 1995 to January 1997, prevention of emesis with granisetron 3 mg/12 h i."7.70The antiemetic efficacy of granisetron plus dexamethasone, haloperidol and loracepam in breast cancer patients treated with high-dose chemotherapy with peripheral blood stem-cell support. ( Aznar, E; Climent, MA; Guillem, V; Olmos, T; Palau, J; Ruiz, A; Soriano, V, 1998)
"Haloperidol (HP) has been shown to have analgesic & antiemetic properties."5.46Haloperidol undermining gastroparesis symptoms (HUGS) in the emergency department. ( Croft, B; Darracq, MA; Ramirez, R; Stalcup, P, 2017)
"The purpose of the study was to compare efficacy and toxicity of olanzapine (OLN; a higher-cost drug) and haloperidol (HAL; a lower-cost drug) in the prevention of chemotherapy-induced nausea and vomiting (CINV) in patients who receive highly emetogenic chemotherapy (HEC)."5.30Randomized Phase II Trial to Compare the Efficacy of Haloperidol and Olanzapine in the Control of Chemotherapy-Induced Nausea and Vomiting in Nepal. ( Acharya, B; Dulal, S; Neupane, P; Paudel, BD; Poudyal, BS; Shah, A; Shilpakar, R; Wood, LA, 2019)
"Haloperidol as an adjunctive therapy is superior to placebo for acute gastroparesis symptoms."5.24Randomized Controlled Double-blind Trial Comparing Haloperidol Combined With Conventional Therapy to Conventional Therapy Alone in Patients With Symptomatic Gastroparesis. ( Cardenas-Turanzas, M; Chambers, KA; Chathampally, Y; Paniagua, L; Patel, S; Roldan, CJ, 2017)
"The topical gel known as "ABH gel," comprising lorazepam (Ativan(®)), diphenhydramine (Benadryl(®)), and haloperidol (Haldol(®)), is frequently used to treat nausea because of its perceived efficacy, relatively low cost, and ease of use in the home setting."5.19A randomized trial of the effectiveness of topical "ABH Gel" (Ativan(®), Benadryl(®), Haldol(®)) vs. placebo in cancer patients with nausea. ( Coyne, PJ; Dodson, PW; Fletcher, DS; Parker, GG; Smith, TJ; Wan, W, 2014)
"Haloperidol is used commonly for the control of nausea and vomiting (N/V) in palliative care patients, but there is very little evidence to support its use."5.14The efficacy of haloperidol in the management of nausea and vomiting in patients with cancer. ( Douglas, C; Gilshenan, K; Hardy, JR; O'Shea, A; Welch, L; White, C, 2010)
" This study compared ziprasidone with the conventional antipsychotic haloperidol in outpatients with stable schizophrenia."5.10A 28-week comparison of ziprasidone and haloperidol in outpatients with stable schizophrenia. ( Bäuml, J; Hirsch, SR; Kissling, W; O'Connor, R; Power, A, 2002)
"Tropisetron is a novel antiserotoninergic drug with potent and specific activity against cancer chemotherapy-induced emesis."5.07Tropisetron plus haloperidol to ameliorate nausea and vomiting associated with high-dose alkylating agent cancer chemotherapy. ( Bonadonna, G; Bregni, M; Di Nicola, M; Gianni, AM; Siena, S, 1991)
"The antiemetic effectiveness of haloperidol plus dexamethasone was compared with that of prochlorperazine plus dexamethasone in a prospective study of patients receiving chemotherapy for breast cancer."5.06A randomized comparison of haloperidol plus dexamethasone versus prochlorperazine plus dexamethasone in preventing nausea and vomiting in patients receiving chemotherapy for breast cancer. ( Carpenter, JT; Conolley, C; Lee, J; Silvey, L; Wheeler, RH, 1988)
"0 mg) of haloperidol with that of placebo for the relief of vomiting and nausea due to gastrointestinal disorders."5.04Haloperidol parenterally for treatment of vomiting and nausea from gastrointestinal disorders in a group of geriatric patients: double-blind, placebo-controlled study. ( Nagel, JD; Robbins, EL, 1975)
"Sixty-two postoperative patients were admitted to a double-blind study to compare the therapeutic effectiveness of a single intramuscular injection of 1 mg of haloperidol with that of a placebo for the relief of vomiting and nausea following surgical procedures."5.04The use of haloperidol for treatment of postoperative nausea and vomiting--a double-blind placebo-controlled trial. ( Barton, MD; Cohen, PJ; Libonati, M, 1975)
"To evaluate the efficacy and adverse events associated with the use of haloperidol for the treatment of nausea and vomiting in palliative care patients."4.91Haloperidol for the treatment of nausea and vomiting in palliative care patients. ( Dorman, S; Murray-Brown, F, 2015)
" In postoperative nausea and vomiting (PONV), two randomized controlled trials found treatment with haloperidol comparable to ondansetron."4.89Using haloperidol as an antiemetic in palliative care: informing practice through evidence from cancer treatment and postoperative contexts. ( Bennett, MI; Blenkinsopp, A; McLean, SL, 2013)
"The primary objective of the review was to evaluate the efficacy and adverse events associated with the use of haloperidol for the treatment of nausea and vomiting in palliative care patients."4.85Haloperidol for the treatment of nausea and vomiting in palliative care patients. ( Dorman, S; Perkins, P, 2009)
"Haloperidol (HL) has successfully been used for nausea and abdominal pain in emergency departments (EDs)."4.02Haloperidol Use in the Emergency Department for Gastrointestinal Symptoms: Nausea, Vomiting, and Abdominal Pain. ( Jehangir, A; Malik, Z; Parkman, HP; Repanshek, ZD; Reznick-Lipina, K; Shahsavari, D; Weiner, M, 2021)
"This randomized controlled trial compared haloperidol along with conventional therapy to placebo along with conventional therapy for gastroparesis in the emergency department."3.88Hot Off the Press: SGEM#196: Gastroparesis-I Feel Like Throwing Up. ( Heitz, C; Milne, WK; Morgenstern, J, 2018)
"For nausea, a commonly encountered symptom in palliative care, clinicians' favored metoclopramide and haloperidol; however, after these choices, there was large variation in antiemetic selection."3.80Prescribing for nausea in palliative care: a cross-sectional national survey of Australian palliative medicine doctors. ( Agar, M; Currow, DC; To, TH; Yates, P, 2014)
" From October 1995 to January 1997, prevention of emesis with granisetron 3 mg/12 h i."3.70The antiemetic efficacy of granisetron plus dexamethasone, haloperidol and loracepam in breast cancer patients treated with high-dose chemotherapy with peripheral blood stem-cell support. ( Aznar, E; Climent, MA; Guillem, V; Olmos, T; Palau, J; Ruiz, A; Soriano, V, 1998)
"5 mg intravenous haloperidol in an effort to improve patient tolerance of cytotoxic chemotherapy and decrease nausea and vomiting."3.66Lorazepam as an adjunct to antiemetic therapy with haloperidol in patients receiving cytotoxic chemotherapy. ( Coates, A; Fox, RM; Friedlander, ML; Hedley, D; Kearsley, JH; Raghavan, D; Sims, K; Tattersall, MH, 1983)
" Ironically, chronic use of cannabis can result in paradoxical effects, including a condition known as cannabinoid hyperemesis syndrome."2.61Cannabinoid hyperemesis syndrome: An unrecognized cause of nausea and vomiting. ( Forest, CP; Smith, TN; Walsh, A, 2019)
"Haloperidol is a butyrophenone neuroleptic agent characterized as a high-affinity dopamine antagonist, originally used for the treatment of schizophrenia."2.48Role of haloperidol in palliative medicine: an update. ( Prommer, E, 2012)
"Haloperidol (HP) has been shown to have analgesic & antiemetic properties."1.46Haloperidol undermining gastroparesis symptoms (HUGS) in the emergency department. ( Croft, B; Darracq, MA; Ramirez, R; Stalcup, P, 2017)
"Treatment with haloperidol (0."1.28Drug-induced purposeless chewing: animal model of dyskinesia or nausea? ( Iversen, SD; Rupniak, NM; Tye, SJ, 1990)

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-199017 (30.91)18.7374
1990's6 (10.91)18.2507
2000's10 (18.18)29.6817
2010's18 (32.73)24.3611
2020's4 (7.27)2.80

Authors

AuthorsStudies
Brown, JM1
Wilsey, MJ1
Dhana, L1
Lonsdale, H1
Trajkovski, A1
Lang, E1
Shahsavari, D1
Reznick-Lipina, K1
Malik, Z1
Weiner, M1
Jehangir, A1
Repanshek, ZD1
Parkman, HP1
Rosenthal, J1
Howell, M1
Earl, V1
Malik, M1
Ramirez, R1
Stalcup, P1
Croft, B1
Darracq, MA1
Roldan, CJ1
Chambers, KA1
Paniagua, L1
Patel, S1
Cardenas-Turanzas, M1
Chathampally, Y1
Heitz, C1
Morgenstern, J1
Milne, WK1
Smith, TN1
Walsh, A1
Forest, CP1
Dulal, S1
Paudel, BD1
Neupane, P1
Shah, A1
Acharya, B1
Poudyal, BS1
Shilpakar, R1
Wood, LA1
Matsuoka, H1
Agar, M2
Vandersman, Z1
Good, P1
Fazekas, B1
Brown, L1
Hardy, J1
Weil, J1
Currow, DC2
Hickey, JL1
Witsil, JC1
Mycyk, MB1
McLean, SL1
Blenkinsopp, A1
Bennett, MI1
Kishi, T1
Mukai, T1
Matsuda, Y1
Iwata, N1
Silvestris, N1
Brunetti, AE1
Russano, M1
Nardulli, P1
Fletcher, DS1
Coyne, PJ1
Dodson, PW1
Parker, GG1
Wan, W1
Smith, TJ1
To, TH1
Yates, P1
Murray-Brown, F1
Dorman, S2
Górska, A1
Marszałł, M1
Sloderbach, A1
Inayat, F1
Virk, HU1
Ullah, W1
Hussain, Q1
Perkins, P1
Hardy, JR1
O'Shea, A1
White, C2
Gilshenan, K1
Welch, L1
Douglas, C1
Prommer, E1
Citrome, L1
DYRBERG, V1
Vella-Brincat, J1
Macleod, AD1
Buss, MK1
Arnold, RM1
Krakauer, EL1
Zhu, AX1
Bounds, BC1
Sahani, D1
McDonald, KR1
Brachtel, EF1
Weschules, DJ1
McPherson, A1
McCann, MA1
Sadler, A1
Fyvie, J1
Siden, HB1
Bleicher, J1
Bhaskara, A1
Huyck, T1
Constantino, S1
Bardia, A1
Loprinzi, CL1
Silberstein, PT1
Friedlander, ML1
Kearsley, JH1
Sims, K1
Coates, A1
Hedley, D1
Raghavan, D1
Fox, RM1
Tattersall, MH1
Uvnäs-Wallensten, K1
Goiny, M1
Judkins, KC1
Harmer, M1
Cole, RM1
Robinson, F1
Harvey, L1
Trethowan, K1
Murdoch, V1
Climent, MA1
Palau, J1
Ruiz, A1
Soriano, V1
Aznar, E1
Olmos, T1
Guillem, V1
Mickle, J1
Critchley, P1
Plach, N1
Grantham, M1
Marshall, D1
Taniguchi, A1
Latimer, E1
Jadad, AR1
Hirsch, SR1
Kissling, W1
Bäuml, J1
Power, A1
O'Connor, R1
Angrist, B1
Ain, M1
Rotrosen, J1
Gershon, S1
Halpern, FS1
Sachar, EJ1
Robbins, EL1
Nagel, JD1
Barton, MD1
Libonati, M1
Cohen, PJ1
Bregni, M1
Siena, S1
Di Nicola, M1
Bonadonna, G1
Gianni, AM1
Francom, M1
Rupniak, NM1
Tye, SJ1
Iversen, SD1
Backonja, M1
Beinlich, B1
Dulli, D1
Schutta, HS1
Murakami, M1
Ota, K1
Silvey, L1
Carpenter, JT1
Wheeler, RH1
Lee, J1
Conolley, C1
Venning, M1
Rogers, J1
Plotkin, DA1
Plotkin, D1
Okun, R1
Christman, RS1
Weinstein, RA1
Larose, JB1
Chibanguza, G1
Cole, DR1
Duffy, DF1
Wolff, JD1
Lionarons, HB1
Mesdag, MJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Haloperidol vs Conventional Therapy for Gastroparesis[NCT02057549]Phase 436 participants (Actual)Interventional2012-11-30Terminated (stopped due to PI left institution)
Droperidol on Prevention of Emesis From Cannabinoid Hyperemesis Syndrome[NCT05244460]Phase 345 participants (Anticipated)Interventional2021-12-02Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Emergency Department Length of Stay (EDLOS)

"The time frame starts from the moment of receiving the study drug to the time when the decision for final disposition is made. Usually after symptoms are controlled, patients are given a PO challenge (food or drink) in order to establish if they are OK to go home. If symptoms return, additional medications are given, the treatment is consider failed and they are admitted to the Hospital.~Patients will not be followed up if admitted to any service. The study ends when final disposition is made.~Patients follow up after final disposition is not part of the study and will not be done." (NCT02057549)
Timeframe: at the time the decision for final disposition is made (about 8 hours)

Interventionhours (Median)
Haloperidol Plus Conventional Therapy4.8
Conventional Therapy9

Nausea Relief as Indicated by Number of Participants Not Requesting Additional Antiemetic Medication

(NCT02057549)
Timeframe: 1 hour after study medication given

InterventionParticipants (Count of Participants)
Haloperidol Plus Conventional Therapy11
Conventional Therapy13

Nausea Score as Measured by a Visual Analogue Scale (VAS)

The Visual Analogue Scale (VAS) ranges from 1-5, with 1 being minimal nausea and 5 being severe nausea. (NCT02057549)
Timeframe: 1 hour after study medication given

Interventionunits on a scale (Mean)
Haloperidol Plus Conventional Therapy1.83
Conventional Therapy3.39

Nausea Score as Measured by a Visual Analogue Scale (VAS)

The Visual Analogue Scale (VAS) ranges from 1-5, with 1 being minimal nausea and 5 being severe nausea. (NCT02057549)
Timeframe: before study medication given

Interventionunits on a scale (Mean)
Haloperidol Plus Conventional Therapy4.53
Conventional Therapy4.11

Number of Participants Admitted to the Hospital After Emergency Department Visit

(NCT02057549)
Timeframe: 2 hours after study medication given

InterventionParticipants (Count of Participants)
Haloperidol Plus Conventional Therapy4
Conventional Therapy13

Pain Relief as Indicated by Number of Participants Not Requesting Additional Pain Medication

(NCT02057549)
Timeframe: 1 hour after study medication given

InterventionParticipants (Count of Participants)
Haloperidol Plus Conventional Therapy11
Conventional Therapy5

Pain Score as Measured by a Visual Analogue Scale (VAS)

The Visual Analogue Scale (VAS) ranges from 0-10, with 0 being the absence of pain and 10 the worst imaginable pain. (NCT02057549)
Timeframe: 1 hour after study medication given

Interventionunits on a scale (Mean)
Haloperidol Plus Conventional Therapy3.13
Conventional Therapy7.17

Pain Score as Measured by a Visual Analogue Scale (VAS)

The Visual Analogue Scale (VAS) ranges from 0-10, with 0 being the absence of pain and 10 the worst imaginable pain. (NCT02057549)
Timeframe: before study medication given

Interventionunits on a scale (Mean)
Haloperidol Plus Conventional Therapy8.50
Conventional Therapy8.28

Reviews

10 reviews available for haloperidol and Nausea

ArticleYear
Cannabinoid hyperemesis syndrome: An unrecognized cause of nausea and vomiting.
    JAAPA : official journal of the American Academy of Physician Assistants, 2019, Volume: 32, Issue:4

    Topics: Acute Disease; Antiemetics; Cannabinoids; Haloperidol; Humans; Lorazepam; Nausea; Syndrome; Vomiting

2019
Using haloperidol as an antiemetic in palliative care: informing practice through evidence from cancer treatment and postoperative contexts.
    Journal of pain & palliative care pharmacotherapy, 2013, Volume: 27, Issue:2

    Topics: Antiemetics; Antineoplastic Agents; Haloperidol; Humans; Nausea; Ondansetron; Palliative Care; Posto

2013
Selective serotonin 3 receptor antagonist treatment for schizophrenia: meta-analysis and systematic review.
    Neuromolecular medicine, 2014, Volume: 16, Issue:1

    Topics: Antipsychotic Agents; Constipation; Double-Blind Method; Drug Therapy, Combination; Granisetron; Hal

2014
Haloperidol for the treatment of nausea and vomiting in palliative care patients.
    The Cochrane database of systematic reviews, 2015, Nov-02, Issue:11

    Topics: Antiemetics; Diphenhydramine; Gels; Haloperidol; Humans; Lorazepam; Nausea; Palliative Care; Randomi

2015
[The neurotoxicity of pyridinium metabolites of haloperidol].
    Postepy higieny i medycyny doswiadczalnej (Online), 2015, Oct-19, Volume: 69

    Topics: Antipsychotic Agents; Biotransformation; Brain; Delirium; Haloperidol; Humans; Nausea; Neurodegenera

2015
Haloperidol for the treatment of nausea and vomiting in palliative care patients.
    The Cochrane database of systematic reviews, 2009, Apr-15, Issue:2

    Topics: Antiemetics; Haloperidol; Humans; Nausea; Palliative Care; Vomiting

2009
Role of haloperidol in palliative medicine: an update.
    The American journal of hospice & palliative care, 2012, Volume: 29, Issue:4

    Topics: Delirium; Dopamine Antagonists; Haloperidol; Humans; Nausea; Palliative Care; Vomiting

2012
Haloperidol in palliative care.
    Palliative medicine, 2004, Volume: 18, Issue:3

    Topics: Antipsychotic Agents; Conscious Sedation; Delirium; Haloperidol; Humans; Long QT Syndrome; Nausea; V

2004
Efficacy of haloperidol in the treatment of nausea and vomiting in the palliative patient: a systematic review.
    Journal of pain and symptom management, 2001, Volume: 22, Issue:2

    Topics: Antiemetics; Haloperidol; Humans; Nausea; Neoplasms; Palliative Care; Vomiting

2001
[Recent advances in the management of chemotherapy-induced emesis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:3 Pt 1

    Topics: Antiemetics; Antineoplastic Agents; Cisplatin; Dexamethasone; Domperidone; Dronabinol; Drug Therapy,

1986

Trials

14 trials available for haloperidol and Nausea

ArticleYear
Randomized Controlled Double-blind Trial Comparing Haloperidol Combined With Conventional Therapy to Conventional Therapy Alone in Patients With Symptomatic Gastroparesis.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2017, Volume: 24, Issue:11

    Topics: Abdominal Pain; Adult; Analgesics; Antiemetics; Double-Blind Method; Drug Therapy, Combination; Fema

2017
Randomized Phase II Trial to Compare the Efficacy of Haloperidol and Olanzapine in the Control of Chemotherapy-Induced Nausea and Vomiting in Nepal.
    Journal of global oncology, 2019, Volume: 5

    Topics: Administration, Intravenous; Administration, Oral; Adult; Antiemetics; Antineoplastic Combined Chemo

2019
Optimal control of nausea and vomiting with a three-drug antiemetic regimen with aprepitant in metastatic pancreatic cancer patients treated with first-line modified FOLFIRINOX.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2013, Volume: 21, Issue:11

    Topics: Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Benztropine; Camptoth

2013
A randomized trial of the effectiveness of topical "ABH Gel" (Ativan(®), Benadryl(®), Haldol(®)) vs. placebo in cancer patients with nausea.
    Journal of pain and symptom management, 2014, Volume: 48, Issue:5

    Topics: Administration, Topical; Adolescent; Adult; Aged; Antiemetics; Cross-Over Studies; Diphenhydramine;

2014
The efficacy of haloperidol in the management of nausea and vomiting in patients with cancer.
    Journal of pain and symptom management, 2010, Volume: 40, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Female; Ha

2010
Lurasidone for the acute treatment of adults with schizophrenia: what is the number needed to treat, number needed to harm, and likelihood to be helped or harmed?
    Clinical schizophrenia & related psychoses, 2012, Volume: 6, Issue:2

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Cholesterol; D

2012
Haloperidol as an adjunct analgesic in the management of postoperative pain.
    Anaesthesia, 1982, Volume: 37, Issue:11

    Topics: Adolescent; Adult; Aged; Drug Administration Schedule; Drug Synergism; Female; Haloperidol; Humans;

1982
A 28-week comparison of ziprasidone and haloperidol in outpatients with stable schizophrenia.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:6

    Topics: Adolescent; Adult; Antipsychotic Agents; Female; Haloperidol; Humans; Male; Middle Aged; Nausea; Pip

2002
Haloperidol parenterally for treatment of vomiting and nausea from gastrointestinal disorders in a group of geriatric patients: double-blind, placebo-controlled study.
    Journal of the American Geriatrics Society, 1975, Volume: 23, Issue:1

    Topics: Age Factors; Aged; Antiemetics; Clinical Trials as Topic; Drug Evaluation; Female; Gastrointestinal

1975
The use of haloperidol for treatment of postoperative nausea and vomiting--a double-blind placebo-controlled trial.
    Anesthesiology, 1975, Volume: 42, Issue:4

    Topics: Abdomen; Adolescent; Adult; Aged; Anesthesia, Inhalation; Anesthetics; Clinical Trials as Topic; Col

1975
Tropisetron plus haloperidol to ameliorate nausea and vomiting associated with high-dose alkylating agent cancer chemotherapy.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:5

    Topics: Adult; Antiemetics; Antineoplastic Agents; Drug Therapy, Combination; Haloperidol; Humans; Indoles;

1991
A randomized comparison of haloperidol plus dexamethasone versus prochlorperazine plus dexamethasone in preventing nausea and vomiting in patients receiving chemotherapy for breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclopho

1988
Low-dose haloperidol as antiemetic treatment in gastrointestinal disorders: a double-blind study.
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:11

    Topics: Antiemetics; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Gastrointestinal Di

1974
Haloperidol for radiation sickness: Control of associated nausea, vomiting, and anorexia.
    New York state journal of medicine, 1974, Volume: 74, Issue:9

    Topics: Adult; Aged; Clinical Trials as Topic; Feeding and Eating Disorders; Female; Haloperidol; Humans; Ma

1974

Other Studies

31 other studies available for haloperidol and Nausea

ArticleYear
Acute Treatment of Adolescent Cannabinoid Hyperemesis Syndrome With Haloperidol, Lorazepam, and/or Capsaicin: A Single Institution Case Series.
    Journal of psychiatric practice, 2023, 09-01, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Cannabinoids; Capsaicin; Child; Haloperidol; Humans; Lorazepam; Nausea; Syndrome;

2023
Haloperidol as an anti-emetic for Cannabis Hyperemesis Syndrome in the ED.
    CJEM, 2021, Volume: 23, Issue:3

    Topics: Antiemetics; Cannabis; Haloperidol; Humans; Nausea; Vomiting

2021
Haloperidol Use in the Emergency Department for Gastrointestinal Symptoms: Nausea, Vomiting, and Abdominal Pain.
    Clinical and translational gastroenterology, 2021, 06-01, Volume: 12, Issue:6

    Topics: Abdominal Pain; Adult; Antiemetics; Diabetes Mellitus; Emergency Service, Hospital; Female; Florida;

2021
Cannabinoid Hyperemesis Syndrome Secondary to Delta-8 THC Use.
    The American journal of medicine, 2021, Volume: 134, Issue:12

    Topics: Administration, Cutaneous; Adult; Antiemetics; Cannabinoid Receptor Agonists; Capsaicin; Dopamine An

2021
Haloperidol undermining gastroparesis symptoms (HUGS) in the emergency department.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:8

    Topics: Abdominal Pain; Adult; Antiemetics; California; Diabetes Mellitus, Type 1; Emergency Service, Hospit

2017
Hot Off the Press: SGEM#196: Gastroparesis-I Feel Like Throwing Up.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2018, Volume: 25, Issue:3

    Topics: Double-Blind Method; Emergency Service, Hospital; Gastroparesis; Haloperidol; Humans; Nausea

2018
Harms From Haloperidol for Symptom Management in Palliative Care-a Post Hoc Pooled Analysis of Three Randomized Controlled Studies and Two Consecutive Cohort Studies.
    Journal of pain and symptom management, 2019, Volume: 58, Issue:3

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Female; Haloperidol; Humans; Male; Middle A

2019
Haloperidol for treatment of cannabinoid hyperemesis syndrome.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:6

    Topics: Abdominal Pain; Adult; Antiemetics; Cannabinoids; Haloperidol; Humans; Male; Marijuana Abuse; Nausea

2013
Prescribing for nausea in palliative care: a cross-sectional national survey of Australian palliative medicine doctors.
    Journal of palliative medicine, 2014, Volume: 17, Issue:9

    Topics: Adult; Antiemetics; Australia; Cross-Sectional Studies; Female; Haloperidol; Humans; Male; Metoclopr

2014
Is haloperidol the wonder drug for cannabinoid hyperemesis syndrome?
    BMJ case reports, 2017, Jan-04, Volume: 2017

    Topics: Adult; Antiemetics; Cannabinoids; Haloperidol; Humans; Male; Marijuana Abuse; Nausea; Syndrome; Trea

2017
Haloperidol (Serenase) in the prevention of postoperative nausea and vomiting.
    Acta anaesthesiologica Scandinavica, 1962, Volume: 6

    Topics: Anesthesia; Haloperidol; Humans; Hypnotics and Sedatives; Nausea; Postoperative Nausea and Vomiting;

1962
Challenges in palliative care research: one experience.
    Journal of palliative medicine, 2004, Volume: 7, Issue:3

    Topics: Antiemetics; Attitude of Health Personnel; Diphenhydramine; Drug Combinations; Ethics Committees, Re

2004
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 6-2005. A 58-year-old man with esophageal cancer and nausea, vomiting, and intractable hiccups.
    The New England journal of medicine, 2005, Feb-24, Volume: 352, Issue:8

    Topics: Adenocarcinoma; Anti-Inflammatory Agents; Antiemetics; Antineoplastic Agents, Hormonal; Barrett Esop

2005
Tolerability of the compound ABHR in hospice patients.
    Journal of palliative medicine, 2005, Volume: 8, Issue:6

    Topics: Aged; Antiemetics; Cohort Studies; Diphenhydramine; Drug Combinations; Female; Haloperidol; Hospice

2005
Prolonged extra-pyramidal side effects after discontinuation of haloperidol as an antiemetic.
    Palliative medicine, 2006, Volume: 20, Issue:3

    Topics: Aged; Antiemetics; Dopamine Antagonists; Female; Haloperidol; Humans; Nausea; Parkinsonian Disorders

2006
Haloperidol as a palliative anti-emetic in a toddler: an evidence base challenge.
    Journal of pain and symptom management, 2008, Volume: 35, Issue:3

    Topics: Antiemetics; Evidence-Based Medicine; Fatal Outcome; Haloperidol; Humans; Infant; Male; Nausea; Pall

2008
Lorazepam, diphenhydramine, and haloperidol transdermal gel for rescue from chemotherapy-induced nausea/vomiting: results of two pilot trials.
    The journal of supportive oncology, 2008, Volume: 6, Issue:1

    Topics: Administration, Cutaneous; Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Clini

2008
Lorazepam as an adjunct to antiemetic therapy with haloperidol in patients receiving cytotoxic chemotherapy.
    Australian and New Zealand journal of medicine, 1983, Volume: 13, Issue:1

    Topics: Anti-Anxiety Agents; Antiemetics; Antineoplastic Agents; Drug Therapy, Combination; Female; Haloperi

1983
Effect of apomorphine on peripheral venous gastrin and insulin levels in conscious dogs.
    Acta physiologica Scandinavica, 1981, Volume: 112, Issue:2

    Topics: Animals; Apomorphine; Dogs; Dose-Response Relationship, Drug; Female; Gastrins; Haloperidol; Insulin

1981
Successful control of intractable nausea and vomiting requiring combined ondansetron and haloperidol in a patient with advanced cancer.
    Journal of pain and symptom management, 1994, Volume: 9, Issue:1

    Topics: Analgesics; Bone Neoplasms; Breast Neoplasms; Drug Therapy, Combination; Female; Haloperidol; Humans

1994
The antiemetic efficacy of granisetron plus dexamethasone, haloperidol and loracepam in breast cancer patients treated with high-dose chemotherapy with peripheral blood stem-cell support.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1998, Volume: 6, Issue:3

    Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dexamethasone;

1998
The use of haloperidol to treat nausea.
    Oncology nursing forum, 1998, Volume: 25, Issue:8

    Topics: Antiemetics; Haloperidol; Humans; Nausea; Neoplasms

1998
Behavioral and neuroendocrine effects of low dose ET-495: antagonism by haloperidol.
    Journal of neural transmission, 1979, Volume: 44, Issue:4

    Topics: Adult; Dose-Response Relationship, Drug; Growth Hormone; Haloperidol; Humans; Male; Middle Aged; Nau

1979
Compounding nausea aid.
    American pharmacy, 1991, Volume: NS31, Issue:7

    Topics: Benztropine; Chemistry, Pharmaceutical; Dexamethasone; Diphenhydramine; Drug Combinations; Drug Comp

1991
Drug-induced purposeless chewing: animal model of dyskinesia or nausea?
    Psychopharmacology, 1990, Volume: 102, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Disease M

1990
Haloperidol and lorazepam for the treatment of nausea and vomiting associated with the treatment of intractable migraine headaches.
    Archives of neurology, 1989, Volume: 46, Issue:7

    Topics: Adult; Dihydroergotamine; Female; Haloperidol; Humans; Lorazepam; Migraine Disorders; Nausea; Vomiti

1989
Continuous subcutaneous infusion: flexible option in symptom control.
    The Australian nurses' journal. Royal Australian Nursing Federation, 1988, Volume: 17, Issue:7

    Topics: Anxiety; Female; Haloperidol; Humans; Infusion Pumps; Infusions, Parenteral; Metoclopramide; Middle

1988
Haloperidol in the treatment of nausea and vomiting due to cytotoxic drug administration.
    Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:9

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Female; Haloperidol; Humans; Male; Middle Aged; N

1973
[The emetic action of theophylline in the dog].
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:1

    Topics: Animals; Chlorpromazine; Dogs; Dose-Response Relationship, Drug; Emetics; Haloperidol; Myotonia; Nau

1974
The effect of haloperidol with promethazine on postoperative vomiting.
    Archivum chirurgicum Neerlandicum, 1970, Volume: 22, Issue:4

    Topics: Anesthesia, General; Atropine; Haloperidol; Humans; Nausea; Promethazine; Vomiting

1970
Occupational health case report--no. 4. Epoxy-type paint.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1974, Volume: 16, Issue:3

    Topics: Air; Animals; Chromatography, Gas; Dermatitis, Occupational; Environmental Exposure; Epoxy Resins; G

1974