haloperidol has been researched along with Myocardial Ischemia in 5 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "N-n-butyl haloperidol (F(2)), a novel compound of quaternary ammonium salt derivatives of haloperidol, was reported to antagonize myocardial ischemia/reperfusion injuries." | 3.76 | Cardiac electrophysiological and antiarrhythmic effects of N-n-butyl haloperidol iodide. ( Chen, YC; Gao, FF; Hao, SY; Huang, ZQ; Liu, XP; Shi, GG; Zhang, YM; Zhou, YQ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, H | 4 |
| Wei, C | 1 |
| Gao, J | 2 |
| Bai, S | 1 |
| Zhao, Y | 1 |
| Han, L | 1 |
| Tian, Y | 2 |
| Yang, G | 1 |
| Wang, R | 2 |
| Wu, L | 1 |
| Xu, C | 1 |
| Gao, FF | 1 |
| Hao, SY | 1 |
| Huang, ZQ | 2 |
| Zhang, YM | 1 |
| Zhou, YQ | 1 |
| Chen, YC | 1 |
| Liu, XP | 1 |
| Shi, GG | 2 |
| Li, HZ | 1 |
| Guo, J | 1 |
| Han, LP | 1 |
| Jiang, CM | 1 |
| Li, HX | 1 |
| Bai, SZ | 1 |
| Zhang, WH | 1 |
| Li, GW | 1 |
| Wang, LN | 1 |
| Zhao, YJ | 1 |
| Lin, Y | 1 |
| Yang, GD | 1 |
| Wu, LY | 1 |
| Yang, BF | 1 |
| Xu, CQ | 1 |
| Zheng, JH | 1 |
| Liu, B | 1 |
| Yan, D | 1 |
| Cheng, LF | 1 |
| Song, HY | 1 |
| Turdi, S | 1 |
| Kerram, P | 1 |
5 other studies available for haloperidol and Myocardial Ischemia
| Article | Year |
|---|---|
Mediation of dopamine D2 receptors activation in post-conditioning-attenuated cardiomyocyte apoptosis.
Topics: Animals; Apoptosis; Bromocriptine; Calcium; Cardiotonic Agents; Caspase 3; Caspase 9; Cell Hypoxia; | 2014 |
Cardiac electrophysiological and antiarrhythmic effects of N-n-butyl haloperidol iodide.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channels, L-Type; | 2010 |
Role of dopamine D2 receptors in ischemia/reperfusion induced apoptosis of cultured neonatal rat cardiomyocytes.
Topics: Animals; Animals, Newborn; Apoptosis; Bromocriptine; Calcium; Cells, Cultured; Dopamine D2 Receptor | 2011 |
Effects of N-n-butyl haloperidol iodide on rat myocardial ischemia and reperfusion injury and L-type calcium current.
Topics: Animals; Calcium Channels, L-Type; Cardiotonic Agents; Haloperidol; Microscopy, Electron; Myocardial | 2003 |
Electrophysiological effects of haloperidol on isolated rabbit Purkinje fibers and guinea pigs papillary muscles under normal and simulated ischemia.
Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Haloperidol; In Vitro Tec | 2007 |