Page last updated: 2024-10-28

haloperidol and Morphine Abuse

haloperidol has been researched along with Morphine Abuse in 25 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Research Excerpts

ExcerptRelevanceReference
"It was found that pimozide, haloperidol and alpha-methyl-p-tyrosine (alpha-MT), drugs inhibiting central catecholaminergic (CA) transmission, increased the development of morphine dependence measured as wet dog shakes in rats."7.66The influence of pimozide, haloperidol, alpha-methyl-p-tyrosine and reserpine on the development of morphine dependence in rats. ( Kruszewska, A; Langwiński, R, 1983)
"It was found that pimozide, haloperidol and alpha-methyl-p-tyrosine (alpha-MT), drugs inhibiting central catecholaminergic (CA) transmission, increased the development of morphine dependence measured as wet dog shakes in rats."3.66The influence of pimozide, haloperidol, alpha-methyl-p-tyrosine and reserpine on the development of morphine dependence in rats. ( Kruszewska, A; Langwiński, R, 1983)
"Pretreatment with haloperidol (0."1.37Haloperidol disrupts opioid-antinociceptive tolerance and physical dependence. ( Chen, Y; Tang, L; Wang, ZJ; Yang, C, 2011)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199020 (80.00)18.7374
1990's3 (12.00)18.2507
2000's1 (4.00)29.6817
2010's1 (4.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yang, C1
Chen, Y1
Tang, L1
Wang, ZJ1
Kawasaki, Y1
Jin, C1
Suemaru, K1
Kawasaki, H1
Shibata, K1
Choshi, T1
Hibino, S1
Gomita, Y1
Araki, H1
Kruszewska, A1
Langwiński, R1
Ferrari, F2
Baggio, G1
Samanin, R1
Cervo, L1
Rochat, C1
Poggesi, E1
Mennini, T1
Fukase, H1
Fukuzaki, K1
Koja, T1
Nagata, R1
Lukas, SE1
Borg, PJ1
Taylor, DA1
Ballard, TM1
McAllister, KH1
Hine, B2
Gershon, S2
Baldino, F1
Cowan, A1
Geller, EB1
Adler, MW1
Zaluzny, SG1
Chesher, GB1
Jackson, DM1
Malor, R1
Maltbie, AA1
Cavenar, JO1
Sullivan, JL1
Hammett, EB1
Eidelberg, E1
Erspamer, R1
Iwamoto, ET1
Way, EL1
Drawbaugh, RB1
Lal, H3
Tseng, LF1
Brase, DA1
Loh, HH1
Friedman, E1
Torrelio, M1
Van der Laan, JW1
Tampieri, A1
Mangiafico, V1
Holtzman, SG1
Cicero, TJ1
Meyer, ER1
Bell, RD1
Schwartz, AS1
Marchok, PL1
Puri, SK1
Puri, S1
Martin, WR1
Eades, CG1
Thompson, WO1
Thompson, JA1
Flanary, HG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Conditioning & Open-Label Placebo (COLP) for Opioid Management in Intensive Inpatient Rehabilitation[NCT05351333]66 participants (Anticipated)Interventional2022-08-03Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

25 other studies available for haloperidol and Morphine Abuse

ArticleYear
Haloperidol disrupts opioid-antinociceptive tolerance and physical dependence.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 338, Issue:1

    Topics: Analgesics, Opioid; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Dose-Response Relat

2011
Effect of glutamate receptor antagonists on place aversion induced by naloxone in single-dose morphine-treated rats.
    British journal of pharmacology, 2005, Volume: 145, Issue:6

    Topics: Animals; Avoidance Learning; Conditioning, Psychological; Dopamine Antagonists; Excitatory Amino Aci

2005
The influence of pimozide, haloperidol, alpha-methyl-p-tyrosine and reserpine on the development of morphine dependence in rats.
    Drug and alcohol dependence, 1983, Volume: 11, Issue:3-4

    Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Catecholamines; Haloperidol; Humans; Male; Methy

1983
Influence of lisuride on morphine withdrawal signs in the rat: a dopamine-mimetic effect.
    Psychopharmacology, 1982, Volume: 78, Issue:4

    Topics: Aggression; Animals; Apomorphine; Dopamine; Ergolines; Haloperidol; Humans; Lisuride; Male; Morphine

1982
Reduction in the number of serotonin receptors in the brainstem of morphine dependent rats: relation to blockade of naloxone precipitated jumping by serotonin agonists.
    Life sciences, 1980, Sep-29, Volume: 27, Issue:13

    Topics: Animals; Behavior, Animal; Brain Stem; Clonidine; Haloperidol; Humans; Male; Morphine Dependence; Na

1980
Effects of morphine, naloxone, buprenorphine, butorphanol, haloperidol and imipramine on morphine withdrawal signs in cynomolgus monkeys.
    Psychopharmacology, 1994, Volume: 116, Issue:4

    Topics: Animals; Behavior, Animal; Buprenorphine; Butorphanol; Haloperidol; Imipramine; Macaca fascicularis;

1994
Voluntary oral morphine self-administration in rats: effect of haloperidol or ondansetron.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:3

    Topics: Animals; Behavior, Animal; Defecation; Haloperidol; Injections, Intramuscular; Male; Morphine; Morph

1994
Acutely administered clozapine does not modify naloxone-induced withdrawal jumping in morphine-dependent mice.
    Pharmacology, biochemistry, and behavior, 1999, Volume: 62, Issue:2

    Topics: Analgesics; Animals; Antipsychotic Agents; Clonidine; Clozapine; Haloperidol; Male; Mice; Morphine D

1999
Haloperidol attenuation of morphine abstinence: synergistic effect of acute lithium administration.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:4

    Topics: Animals; Drug Synergism; Haloperidol; Humans; Lithium; Male; Methyltyrosines; Morphine Dependence; N

1977
Effects of antipsychotic and antianxiety drugs on the morphine abstinence syndrome in rats.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 208, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Behavior, Animal; Body Weight; Chlordiazepoxide;

1979
The attenuation of delta 9-tetrahydrocannabinol and morphine of the quasi-morphine withdrawal syndrome in rats.
    Psychopharmacology, 1979, Mar-22, Volume: 61, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Behavior, Animal; Chlordiazepoxide; Dronabinol; Haloperidol; H

1979
Haloperidol treatment of a sixty-year narcotic addiction: case report.
    Military medicine, 1979, Volume: 144, Issue:4

    Topics: Aged; Haloperidol; Humans; Male; Morphine Dependence; Time Factors

1979
Dopaminergic mechanisms of opiate actions in brain.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:1

    Topics: Analgesics; Animals; Brain; Dopamine; Drug Synergism; Drug Tolerance; Haloperidol; Humans; Levodopa;

1975
Circling behavior and stereotypy induced by intranigral opiate microinjections.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 203, Issue:2

    Topics: Analgesia; Animals; Behavior; Endorphins; Haloperidol; Humans; Hydroxydopamines; Injections; Male; M

1977
Effect of pharmacological interference with various neuropathways on blockade of morphine-withdrawal hypothermia by morphine and by conditional stimulus.
    Neuropharmacology, 1976, Volume: 15, Issue:6

    Topics: Animals; Benztropine; Conditioning, Classical; Cyproheptadine; Haloperidol; Humans; Hypothermia; Mal

1976
Dopaminergic influence on withdrawal jumping behavior in morphine-dependent mice.
    Research communications in chemical pathology and pharmacology, 1976, Volume: 15, Issue:3

    Topics: Animals; Apomorphine; Brain; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Humans; Male;

1976
Tetrahydrocannabinol-attenuated abstinence and induced rotation in morphine-dependent rats: possible involvement of dopamine.
    Neuropharmacology, 1975, Volume: 14, Issue:8

    Topics: Animals; Behavior; Cannabis; Dopamine; Dronabinol; Haloperidol; Humans; Male; Morphine Dependence; N

1975
Dopaminergic and alpha 1-adrenergic properties of B-HT920 revealed in morphine-dependent rats.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 26, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Dopamine; Haloperidol; Lisuride; Male; Morphine Depend

1987
Imidazole modification of aggressive behaviour in rats and mice.
    Life sciences, 1987, Jun-15, Volume: 40, Issue:24

    Topics: Aggression; Animals; Haloperidol; Imidazoles; Lisuride; Male; Mice; Morphine Dependence; Rats; Rats,

1987
Discriminative stimulus effects of morphine withdrawal in the dependent rat: suppression by opiate and nonopiate drugs.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:1

    Topics: Animals; Body Weight; Clonidine; Haloperidol; Humans; Male; Morphine Dependence; Naloxone; Naltrexon

1985
Effects of phenoxybenzamine on the narcotic withdrawal syndrome in the rat.
    Neuropharmacology, 1974, Volume: 13, Issue:7

    Topics: Adrenergic beta-Antagonists; Animals; Behavior, Animal; Body Weight; Chlorpromazine; Depression, Che

1974
Depression of morphine-seeking behaviour by dopamine inhibition.
    Nature, 1974, Mar-15, Volume: 248, Issue:445

    Topics: Animals; Chelating Agents; Conditioning, Operant; Dopamine Antagonists; Dopamine beta-Hydroxylase; F

1974
Tolerance to the behavioral and neurochemical effects of haloperidol and morphine in rats chronically treated with morphine or haloperidol.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:2

    Topics: Animals; Behavior, Animal; Catalepsy; Corpus Striatum; Dopamine; Drug Tolerance; Haloperidol; Humans

1974
Effect of dopaminergic stimulation or blockade on morphine-withdrawal aggression.
    Psychopharmacologia, 1973, Volume: 32, Issue:2

    Topics: Aggression; Amphetamine; Animals; Apomorphine; Dihydroxyphenylalanine; Haloperidol; Humans; Male; Me

1973
Morphine physical dependence in the dog.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:3

    Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Dogs; Dose-Response Relationship, Drug; Ha

1974