Page last updated: 2024-10-28

haloperidol and Metabolic Syndrome

haloperidol has been researched along with Metabolic Syndrome in 7 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.

Research Excerpts

ExcerptRelevanceReference
"To determine whether the prescription of aripiprazole, compared with olanzapine and haloperidol, was associated with a lower frequency of metabolic syndrome (MS) and treatment discontinuation at 1 year."9.22Metabolic syndrome and drug discontinuation in schizophrenia: a randomized trial comparing aripiprazole olanzapine and haloperidol. ( Barbato, A; D'Avanzo, B; Parabiaghi, A; Tettamanti, M, 2016)
"Haloperidol or clozapine was orally fed to male and female Sprague Dawley rats for 12 weeks, and body weight gain, food and water intake were measured."7.79The sex-dependent impact of chronic clozapine and haloperidol treatment on characteristics of the metabolic syndrome in a rat model. ( Bouvier, ML; Gaebel, W; Henning, U; Schmitt, A; Schneider-Axmann, T; von Wilmsdorff, M, 2013)
"To determine whether the prescription of aripiprazole, compared with olanzapine and haloperidol, was associated with a lower frequency of metabolic syndrome (MS) and treatment discontinuation at 1 year."5.22Metabolic syndrome and drug discontinuation in schizophrenia: a randomized trial comparing aripiprazole olanzapine and haloperidol. ( Barbato, A; D'Avanzo, B; Parabiaghi, A; Tettamanti, M, 2016)
"Haloperidol or clozapine was orally fed to male and female Sprague Dawley rats for 12 weeks, and body weight gain, food and water intake were measured."3.79The sex-dependent impact of chronic clozapine and haloperidol treatment on characteristics of the metabolic syndrome in a rat model. ( Bouvier, ML; Gaebel, W; Henning, U; Schmitt, A; Schneider-Axmann, T; von Wilmsdorff, M, 2013)
"We recruited 109 patients with schizophrenia treated with clozapine or haloperidol and evaluated their body mass index (BMI), waist circumference, blood pressure, and fasting triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), fasting plasma glucose, insulin, RBP4, total adiponectin, and HMW adiponectin levels."3.77Association of plasma retinol-binding protein-4, adiponectin, and high molecular weight adiponectin with metabolic adversities in patients with schizophrenia. ( Chen, CH; Chen, PY; Chiu, CC; Huang, MC; Liu, HC; Lu, ML, 2011)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's5 (71.43)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Bouvier, ML2
Fehsel, K1
Schmitt, A2
Meisenzahl-Lechner, E1
Gaebel, W2
von Wilmsdorff, M2
Aly El-Gabry, DM1
Abdel Aziz, K1
Okasha, T1
Azzam, H1
Okasha, A1
Parabiaghi, A1
Tettamanti, M1
D'Avanzo, B1
Barbato, A1
Cohen, D1
de Hert, M1
Chen, PY1
Huang, MC1
Chiu, CC1
Liu, HC1
Lu, ML1
Chen, CH1
Henning, U1
Schneider-Axmann, T1
Mosolov, SN1
Kabanov, SO1

Reviews

1 review available for haloperidol and Metabolic Syndrome

ArticleYear
[The appearance of metabolic syndrome in treatment with atypical antipsychotics].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2003, Volume: 103, Issue:11

    Topics: Adolescent; Adult; Age Factors; Aged; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Body W

2003

Trials

1 trial available for haloperidol and Metabolic Syndrome

ArticleYear
Metabolic syndrome and drug discontinuation in schizophrenia: a randomized trial comparing aripiprazole olanzapine and haloperidol.
    Acta psychiatrica Scandinavica, 2016, Volume: 133, Issue:1

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Female; Follow-Up Studies; Haloperidol;

2016

Other Studies

5 other studies available for haloperidol and Metabolic Syndrome

ArticleYear
Sex-dependent effects of long-term clozapine or haloperidol medication on red blood cells and liver iron metabolism in Sprague Dawley rats as a model of metabolic syndrome.
    BMC pharmacology & toxicology, 2022, 01-15, Volume: 23, Issue:1

    Topics: Animals; Antipsychotic Agents; Clozapine; Erythrocytes; Female; Haloperidol; Humans; Iron; Liver; Ma

2022
Antipsychotic Polypharmacy and Its Relation to Metabolic Syndrome in Patients With Schizophrenia: An Egyptian Study.
    Journal of clinical psychopharmacology, 2018, Volume: 38, Issue:1

    Topics: Adult; Antipsychotic Agents; Cross-Sectional Studies; Delayed-Action Preparations; Drug Therapy, Com

2018
[Reaction on 'Antipsychotics and metabolic abnormalities in children and adolescents; a review of the literature and some recommendations'].
    Tijdschrift voor psychiatrie, 2010, Volume: 52, Issue:8

    Topics: Adolescent; Antipsychotic Agents; Child; Energy Metabolism; Evidence-Based Medicine; Haloperidol; Hu

2010
Association of plasma retinol-binding protein-4, adiponectin, and high molecular weight adiponectin with metabolic adversities in patients with schizophrenia.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Dec-01, Volume: 35, Issue:8

    Topics: Adiponectin; Adult; Antipsychotic Agents; Blood Pressure; Body Mass Index; Clozapine; Female; Halope

2011
The sex-dependent impact of chronic clozapine and haloperidol treatment on characteristics of the metabolic syndrome in a rat model.
    Pharmacopsychiatry, 2013, Volume: 46, Issue:1

    Topics: Adiposity; Animals; Antipsychotic Agents; Blood Glucose; Body Weight; Clozapine; Drinking; Eating; F

2013