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haloperidol and Memory Disorders

haloperidol has been researched along with Memory Disorders in 30 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Memory Disorders: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this article was to report a case of chorea that developed in an elderly man being treated with gabapentin for severe anxiety."7.75Chorea associated with gabapentin use in an elderly man. ( Attupurath, R; Aziz, R; Muralee, S; Tampi, RR; Wollman, D, 2009)
"307 schizophrenia subjects in their first episode of illness were recruited to participate in a clinical trial comparing the long-term efficacy of haloperidol and risperidone."5.11Correlates of cognitive deficits in first episode schizophrenia. ( Csernansky, JG; DeLisi, LE; Heydebrand, G; Hoff, AL; Rabinowitz, J; Weiser, M, 2004)
" phencyclidine (PCP), produces prolonged impairment of novel object recognition (NOR), suggesting they constitute a hypoglutamate-based model of cognitive impairment in schizophrenia (CIS)."3.81Combined serotonin (5-HT)1A agonism, 5-HT(2A) and dopamine D₂ receptor antagonism reproduces atypical antipsychotic drug effects on phencyclidine-impaired novel object recognition in rats. ( Horiguchi, M; Meltzer, HY; Miyauchi, M; Oyamada, Y; Rajagopal, L, 2015)
"The purpose of this article was to report a case of chorea that developed in an elderly man being treated with gabapentin for severe anxiety."3.75Chorea associated with gabapentin use in an elderly man. ( Attupurath, R; Aziz, R; Muralee, S; Tampi, RR; Wollman, D, 2009)
" Phencyclidine (PCP), a non-competitive NMDA-receptor antagonist, is able to induce schizophrenia-like symptoms in animals and in humans."3.70Neuroleptics ameliorate phencyclidine-induced impairments of short-term memory. ( Sabel, BA; Schroeder, H; Schroeder, U; Schwegler, H, 2000)
"Haloperidol-induced increase in malondialdehyde and nitrite generation as well as deficits in antioxidant enzymes activities were attenuated by chronic administration of vinpocetine."1.56Vinpocetine prevents haloperidol-induced cognitive and working memory deficits through attenuation of oxidative and nitrosative stress in mice. ( Adeyemi, OO; Isaac, AI; Ishola, IO, 2020)
"The aim of study was to investigate the effects of pyrroloquinoline quinone (PQQ) combined with d-serine on the modulation of glycine sites in the brain of rats using social recognition test."1.43Modulation of glycine sites enhances social memory in rats using PQQ combined with d-serine. ( Liu, D; Mao, S; Peng, Y; Qin, X; Zhang, R; Zhou, X, 2016)
"Haloperidol (HAL) is an antipsychotic drug that has high affinities to the dopamine D(2), but low affinities to D(1) receptors in the brain."1.38Chronic haloperidol-induced spatial memory deficits accompany the upregulation of D(1) and D(2) receptors in the caudate putamen of C57BL/6 mouse. ( Rose, GM; Xu, H; Yang, HJ, 2012)
"Although chronic use of methamphetamine (METH) leads to long-lasting cognitive dysfunction in humans, there are few reports about an animal model that reflects METH-induced impairment of working memory."1.34Repeated methamphetamine treatment impairs spatial working memory in rats: reversal by clozapine but not haloperidol. ( Dohniwa, M; Ibi, D; Kamei, H; Mizoguchi, H; Nabeshima, T; Nagai, T; Takuma, K; Yamada, K, 2007)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.33)18.7374
1990's5 (16.67)18.2507
2000's13 (43.33)29.6817
2010's10 (33.33)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Ishola, IO1
Isaac, AI1
Adeyemi, OO1
Onaolapo, OJ1
Paul, TB1
Onaolapo, AY1
Aoyama, Y1
Mouri, A1
Toriumi, K1
Koseki, T1
Narusawa, S1
Ikawa, N1
Mamiya, T1
Nagai, T3
Yamada, K4
Nabeshima, T5
França, AS2
do Nascimento, GC1
Lopes-dos-Santos, V1
Muratori, L2
Ribeiro, S2
Lobão-Soares, B2
Tort, AB1
Oyamada, Y1
Horiguchi, M1
Rajagopal, L1
Miyauchi, M1
Meltzer, HY1
Nascimento, GC1
Pereira, CM1
Zhou, X1
Liu, D1
Zhang, R1
Peng, Y1
Qin, X1
Mao, S1
Rajput, SK1
Sharma, AK1
Meena, CL1
Pant, AB1
Jain, R1
Sharma, SS1
Murai, R1
Matsui, K1
Kamei, H2
Noda, Y3
Furukawa, H1
Barcelos, RC1
Benvegnú, DM1
Boufleur, N1
Reckziegel, P1
Müller, LG1
Pase, C1
Emanuelli, T1
Bürger, ME2
Attupurath, R1
Aziz, R1
Wollman, D1
Muralee, S1
Tampi, RR1
López-Téllez, JF1
López-Aranda, MF1
Navarro-Lobato, I1
Masmudi-Martín, M1
Montañez, EM1
Calvo, EB1
Khan, ZU1
Xu, H1
Yang, HJ1
Rose, GM1
Dietl, T1
Herr, A1
Brunner, H1
Friess, E1
Heydebrand, G1
Weiser, M1
Rabinowitz, J1
Hoff, AL1
DeLisi, LE1
Csernansky, JG1
Wezenberg, E1
Sabbe, BG1
Hulstijn, W1
Ruigt, GS1
Verkes, RJ1
Morice, E1
Billard, JM1
Denis, C1
Mathieu, F1
Betancur, C1
Epelbaum, J1
Giros, B1
Nosten-Bertrand, M1
Takuma, K2
Dohniwa, M1
Ibi, D2
Mizoguchi, H2
Mihara, T1
Mihara, K1
Yarimizu, J1
Mitani, Y1
Matsuda, R1
Yamamoto, H1
Aoki, S1
Akahane, A1
Iwashita, A1
Matsuoka, N1
Fukakusa, A1
Ito, Y1
Nakatani, A1
Kim, HC1
Terry, AV1
Gearhart, DA1
Warner, S1
Hohnadel, EJ1
Middlemore, ML1
Zhang, G1
Bartlett, MG1
Mahadik, SP1
Colpo, G1
Trevisol, F1
Teixeira, AM1
Fachinetto, R1
Pereira, RP1
Athayde, ML1
Rocha, JB1
Egashira, N1
Ishigami, N1
Mishima, K1
Iwasaki, K1
Oishi, R1
Fujiwara, M1
Maurice, T2
Junien, JL1
Privat, A2
Tang, YP1
Gilbertson, MW1
van Kammen, DP1
Phan, VL1
Schroeder, U1
Schroeder, H1
Schwegler, H1
Sabel, BA1
Lazarova-Bakarova, MB1
Petkova, BP1
Todorov, IK1
Petkov, VD1
Siegel, GJ1
Mones, RJ1

Trials

3 trials available for haloperidol and Memory Disorders

ArticleYear
Correlates of cognitive deficits in first episode schizophrenia.
    Schizophrenia research, 2004, May-01, Volume: 68, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Cognition Disorders; Diagnostic and Statistical Manual of M

2004
The role of sedation tests in identifying sedative drug effects in healthy volunteers and their power to dissociate sedative-related impairments from memory dysfunctions.
    Journal of psychopharmacology (Oxford, England), 2007, Volume: 21, Issue:6

    Topics: Adult; Affect; Antipsychotic Agents; Arousal; Benzodiazepines; Choice Behavior; Cross-Over Studies;

2007
Recent and remote memory dissociation: medication effects and hippocampal function in schizophrenia.
    Biological psychiatry, 1997, Oct-01, Volume: 42, Issue:7

    Topics: Adult; Antipsychotic Agents; Attention; Double-Blind Method; Haloperidol; Hippocampus; Humans; Male;

1997

Other Studies

27 other studies available for haloperidol and Memory Disorders

ArticleYear
Vinpocetine prevents haloperidol-induced cognitive and working memory deficits through attenuation of oxidative and nitrosative stress in mice.
    Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria, 2020, Dec-31, Volume: 35, Issue:2

    Topics: Animals; Cognition; Haloperidol; Memory Disorders; Memory, Short-Term; Mice; Nitrosative Stress; Oxi

2020
Comparative effects of sertraline, haloperidol or olanzapine treatments on ketamine-induced changes in mouse behaviours.
    Metabolic brain disease, 2017, Volume: 32, Issue:5

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Anxiety; Behavior, Animal; Benzodiazepines; Do

2017
Clozapine ameliorates epigenetic and behavioral abnormalities induced by phencyclidine through activation of dopamine D1 receptor.
    The international journal of neuropsychopharmacology, 2014, Volume: 17, Issue:5

    Topics: Animals; Antipsychotic Agents; Benzazepines; Butyric Acid; Calcium-Calmodulin-Dependent Protein Kina

2014
Beta2 oscillations (23-30 Hz) in the mouse hippocampus during novel object recognition.
    The European journal of neuroscience, 2014, Volume: 40, Issue:11

    Topics: Animals; Beta Rhythm; Electrodes, Implanted; Exploratory Behavior; Haloperidol; Hippocampus; Memory

2014
Combined serotonin (5-HT)1A agonism, 5-HT(2A) and dopamine D₂ receptor antagonism reproduces atypical antipsychotic drug effects on phencyclidine-impaired novel object recognition in rats.
    Behavioural brain research, 2015, May-15, Volume: 285

    Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dopamine D2 Receptor Antagonists; Haloperidol

2015
Object recognition impairment and rescue by a dopamine D2 antagonist in hyperdopaminergic mice.
    Behavioural brain research, 2016, 07-15, Volume: 308

    Topics: Animals; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationsh

2016
Modulation of glycine sites enhances social memory in rats using PQQ combined with d-serine.
    Behavioural brain research, 2016, 07-15, Volume: 308

    Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Drug Contamination; Drug Synergism; G

2016
Effect of L-pGlu-(1-benzyl)-l-His-l-Pro-NH
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain Ischemia; Catalepsy; Cell Death; Diseas

2016
Aripiprazole ameliorates phencyclidine-induced impairment of recognition memory through dopamine D1 and serotonin 5-HT1A receptors.
    Psychopharmacology, 2009, Volume: 202, Issue:1-3

    Topics: Animals; Antipsychotic Agents; Aripiprazole; Dopamine Antagonists; Dopamine D2 Receptor Antagonists;

2009
Effects of omega-3 essential fatty acids (omega-3 EFAs) on motor disorders and memory dysfunction typical neuroleptic-induced: behavioral and biochemical parameter.
    Neurotoxicity research, 2010, Volume: 17, Issue:3

    Topics: Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Catalepsy; Disease Models, An

2010
Chorea associated with gabapentin use in an elderly man.
    The American journal of geriatric pharmacotherapy, 2009, Volume: 7, Issue:4

    Topics: Aged; Amines; Analgesics; Anti-Dyskinesia Agents; Anxiety; Chorea; Cognition Disorders; Cyclohexanec

2009
Prefrontal inositol triphosphate is molecular correlate of working memory in nonhuman primates.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Feb-24, Volume: 30, Issue:8

    Topics: Amphetamine; Animals; Antipsychotic Agents; Calcium; Calcium Signaling; Central Nervous System Stimu

2010
Chronic haloperidol-induced spatial memory deficits accompany the upregulation of D(1) and D(2) receptors in the caudate putamen of C57BL/6 mouse.
    Life sciences, 2012, Sep-24, Volume: 91, Issue:9-10

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Blotting, Western; Brain; Caudate Nucleus; Dose-Res

2012
Capgras syndrome--out of sight, out of mind?
    Acta psychiatrica Scandinavica, 2003, Volume: 108, Issue:6

    Topics: Antipsychotic Agents; Brain; Capgras Syndrome; Female; Haloperidol; Humans; Memory Disorders; Middle

2003
Parallel loss of hippocampal LTD and cognitive flexibility in a genetic model of hyperdopaminergia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:10

    Topics: Animals; Brain Diseases, Metabolic; Cognition Disorders; Disease Models, Animal; Dopamine; Dopamine

2007
Repeated methamphetamine treatment impairs spatial working memory in rats: reversal by clozapine but not haloperidol.
    Psychopharmacology, 2007, Volume: 194, Issue:1

    Topics: Administration, Oral; Animals; Antipsychotic Agents; Blotting, Western; Central Nervous System Stimu

2007
Pharmacological characterization of a novel, potent adenosine A1 and A2A receptor dual antagonist, 5-[5-amino-3-(4-fluorophenyl)pyrazin-2-yl]-1-isopropylpyridine-2(1H)-one (ASP5854), in models of Parkinson's disease and cognition.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 323, Issue:2

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Aminopyridines; Ani

2007
Improvement by minocycline of methamphetamine-induced impairment of recognition memory in mice.
    Psychopharmacology, 2008, Volume: 196, Issue:2

    Topics: Animals; Behavior, Animal; Clozapine; Dose-Response Relationship, Drug; Exploratory Behavior; Halope

2008
Protracted effects of chronic oral haloperidol and risperidone on nerve growth factor, cholinergic neurons, and spatial reference learning in rats.
    Neuroscience, 2007, Dec-05, Volume: 150, Issue:2

    Topics: Acetylcholine; Administration, Oral; Animals; Antipsychotic Agents; Basal Nucleus of Meynert; Brain;

2007
Ilex paraguariensis has antioxidant potential and attenuates haloperidol-induced orofacial dyskinesia and memory dysfunction in rats.
    Neurotoxicity research, 2007, Volume: 12, Issue:3

    Topics: Animals; Antioxidants; Behavior, Animal; Haloperidol; Ilex paraguariensis; In Vitro Techniques; Male

2007
Delta9-Tetrahydrocannabinol-induced cognitive deficits are reversed by olanzapine but not haloperidol in rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Feb-15, Volume: 32, Issue:2

    Topics: Acetylcholine; Animals; Antipsychotic Agents; Behavior, Animal; Benzodiazepines; Cognition Disorders

2008
Dehydroepiandrosterone sulfate attenuates dizocilpine-induced learning impairment in mice via sigma 1-receptors.
    Behavioural brain research, 1997, Volume: 83, Issue:1-2

    Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Dehydroepiandrosterone Sulfate; Dizocilpine Maleat

1997
Involvement of activation of dopaminergic neuronal system in learning and memory deficits associated with experimental mild traumatic brain injury.
    The European journal of neuroscience, 1997, Volume: 9, Issue:8

    Topics: Animals; Apomorphine; Benzazepines; Brain Injuries; Dopamine; Dopamine Agonists; Dopamine Antagonist

1997
The attenuation of learning impairments induced after exposure to CO or trimethyltin in mice by sigma (sigma) receptor ligands involves both sigma1 and sigma2 sites.
    British journal of pharmacology, 1999, Volume: 127, Issue:2

    Topics: Amnesia; Animals; Anticonvulsants; Avoidance Learning; Carbon Monoxide; Ethylamines; Guanidines; Hal

1999
Neuroleptics ameliorate phencyclidine-induced impairments of short-term memory.
    British journal of pharmacology, 2000, Volume: 130, Issue:1

    Topics: Animals; Antipsychotic Agents; Benzazepines; Brain; Excitatory Amino Acid Antagonists; Glutamic Acid

2000
Memory impairment induced by combined disturbance of noradrenergic and dopaminergic neurotransmissions: effects of nootropic drugs.
    Acta physiologica et pharmacologica Bulgarica, 1991, Volume: 17, Issue:1

    Topics: Animals; Avoidance Learning; Benzoates; Central Nervous System Agents; Clonidine; Dopamine; Haloperi

1991
Modification of choreiform activity by Haloperidol.
    JAMA, 1971, Apr-26, Volume: 216, Issue:4

    Topics: Administration, Oral; Chorea; Chronic Disease; Electrocardiography; Female; Haloperidol; Humans; Mem

1971