haloperidol has been researched along with Leukemia in 3 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Haloperidol was less potent than verapamil." | 1.31 | Reversal of vinblastine resistance in human leukemic cells by haloperidol and dihydrohaloperidol. ( Fujita, R; Furusawa, S; Ishikawa, M; Kataoka, Y; Miura, M; Sasaki, K; Takayanagi, M; Takayanagi, Y; Takeshita, M, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vilner, BJ | 1 |
| John, CS | 1 |
| Bowen, WD | 1 |
| Kataoka, Y | 1 |
| Ishikawa, M | 1 |
| Miura, M | 1 |
| Takeshita, M | 1 |
| Fujita, R | 1 |
| Furusawa, S | 1 |
| Takayanagi, M | 1 |
| Takayanagi, Y | 1 |
| Sasaki, K | 1 |
| Weisenthal, LM | 1 |
| Su, YZ | 1 |
| Duarte, TE | 1 |
| Dill, PL | 1 |
| Nagourney, RA | 1 |
3 other studies available for haloperidol and Leukemia
| Article | Year |
|---|---|
Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines.
Topics: Adenocarcinoma; Animals; Binding, Competitive; Breast Neoplasms; Carcinoma, Ductal, Breast; Glioblas | 1995 |
Reversal of vinblastine resistance in human leukemic cells by haloperidol and dihydrohaloperidol.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; | 2001 |
Perturbation of in vitro drug resistance in human lymphatic neoplasms by combinations of putative inhibitors of protein kinase C.
Topics: Cell Survival; Chlorpromazine; Drug Resistance; Drug Synergism; Haloperidol; Humans; Imipramine; In | 1987 |