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haloperidol and Intraocular Pressure

haloperidol has been researched along with Intraocular Pressure in 18 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Intraocular Pressure: The pressure of the fluids in the eye.

Research Excerpts

ExcerptRelevanceReference
"In a double-blind randomised, prospective single dose study, we measured intraocular pressure (IOP), pupil diameter, systemic blood pressure and heart rate in 43 ocular normotensive subjects before (baseline) and 2, 4, and 6 hours after topical instillation of the following drugs: dopamine 2% (n = 11), a dopamine receptor blocking drug, haloperidol 0."9.07The effects of dopamine, haloperidol and bromocriptine on intraocular pressure. ( Elibol, O; Güler, C; Yüksel, N, 1992)
"Haloperidol, a dopaminergic antagonist, was found to be very effective in lowering intraocular pressure in normal and glaucomatous eyes."7.69Evaluation of haloperidol, a dopamine antagonist, on intraocular pressure in experimental glaucoma. ( Gupta, MC; Khosla, P; Kothari, S; Srivastava, RK, 1996)
"Melatonin injected into the vortex vein of a rabbit eye produced an increase in intraocular pressure (IOP) which lasted for up to 5 h."7.68Effects of melatonin and haloperidol given via vortex vein on the intraocular pressure. ( Chiou, GC; Li, BH; Rohde, BH, 1993)
"Although it is essential that intraocular pressure (IOP) be reduced in glaucoma treatment, it is also vitally important to provide sufficient blood flow to eye tissues so that healthy visual field is maintained."7.67Effects of antiglaucoma drugs on the blood flow in rabbit eyes. ( Chiou, GC; Yan, HY, 1986)
"In a double-blind randomised, prospective single dose study, we measured intraocular pressure (IOP), pupil diameter, systemic blood pressure and heart rate in 43 ocular normotensive subjects before (baseline) and 2, 4, and 6 hours after topical instillation of the following drugs: dopamine 2% (n = 11), a dopamine receptor blocking drug, haloperidol 0."5.07The effects of dopamine, haloperidol and bromocriptine on intraocular pressure. ( Elibol, O; Güler, C; Yüksel, N, 1992)
" PEGDE films were also tested for their effects in the treatment of intraocular pressure (IOP) in rabbits using timolol maleate (TM) as the model drug."3.79Novel bioadhesive hyaluronan-itaconic acid crosslinked films for ocular therapy. ( Calles, JA; Diebold, Y; Lopez-García, A; Palma, SD; Tártara, LI; Vallés, EM, 2013)
"Melatonin injected into the vortex vein of a rabbit eye produced an increase in intraocular pressure (IOP) which lasted for up to 5 h."3.68Effects of melatonin and haloperidol given via vortex vein on the intraocular pressure. ( Chiou, GC; Li, BH; Rohde, BH, 1993)
"Although it is essential that intraocular pressure (IOP) be reduced in glaucoma treatment, it is also vitally important to provide sufficient blood flow to eye tissues so that healthy visual field is maintained."3.67Effects of antiglaucoma drugs on the blood flow in rabbit eyes. ( Chiou, GC; Yan, HY, 1986)
"Bilateral intraocular pressures were monitored before and after the first 7 ECTs and intermittently after ECT for 10 months of maintenance ECT."1.40Stability of intraocular pressure after retinal reattachment surgery during electroconvulsive therapy for intractable self-injury in a 12-year-old autistic boy. ( Reti, IM; Wachtel, LE; Ying, H, 2014)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199011 (61.11)18.7374
1990's5 (27.78)18.2507
2000's0 (0.00)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wachtel, LE1
Reti, IM1
Ying, H1
GEORGIADES, G1
KYRATSOS, C1
MICHAILIDES, G1
TSINOPOULOS, T1
Bandych-Biniszkiewiczowa, D1
Chiou, GC4
Rohde, BH1
Li, BH1
Khosla, P2
Kothari, S2
Gupta, MC2
Srivastava, RK1
Shannon, RP1
Mead, A1
Sears, ML1
Elibol, O1
Güler, C1
Yüksel, N1
Chen, YJ1
Xia, XP1
Sheppard, JD1
Schaid, DJ2
Sheppard, J1
Lavin, MJ1
Andrews, V1
Yan, HY1
Dom, R1
Van Lommel, R1
Baro, F1
Schmiedeberg, W1
Thiel, HJ1
van Zwieten, PA1
Calles, JA1
Tártara, LI1
Lopez-García, A1
Diebold, Y1
Palma, SD1
Vallés, EM1

Trials

5 trials available for haloperidol and Intraocular Pressure

ArticleYear
The effects of dopamine, haloperidol and bromocriptine on intraocular pressure.
    International ophthalmology, 1992, Volume: 16, Issue:4-5

    Topics: Adult; Bromocriptine; Dopamine; Double-Blind Method; Glaucoma; Haloperidol; Humans; Intraocular Pres

1992
Oral haloperidol lowers human intraocular pressure.
    Journal of ocular pharmacology, 1986,Summer, Volume: 2, Issue:3

    Topics: Administration, Oral; Adult; Aged; Female; Glaucoma; Haloperidol; Humans; Intraocular Pressure; Male

1986
Ocular hypotensive effect of haloperidol.
    Transactions - Pennsylvania Academy of Ophthalmology and Otolaryngology, 1986, Volume: 38, Issue:1

    Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma; Haloperidol; Humans; I

1986
Is topical haloperidol a useful glaucoma treatment?
    The British journal of ophthalmology, 1986, Volume: 70, Issue:6

    Topics: Administration, Topical; Double-Blind Method; Glaucoma; Haloperidol; Humans; Intraocular Pressure; K

1986
A quantitative study of neuroleptic-induced extrapyramidal symptoms and their response to dexetimide, a potent and long-acting antiparkinsonian agent.
    Acta psychiatrica Scandinavica, 1971, Volume: 47, Issue:4

    Topics: Administration, Oral; Adult; Antiparkinson Agents; Basal Ganglia Diseases; Benztropine; Benzyl Compo

1971

Other Studies

13 other studies available for haloperidol and Intraocular Pressure

ArticleYear
Stability of intraocular pressure after retinal reattachment surgery during electroconvulsive therapy for intractable self-injury in a 12-year-old autistic boy.
    The journal of ECT, 2014, Volume: 30, Issue:1

    Topics: Aggression; Anticonvulsants; Antipsychotic Agents; Autistic Disorder; Child; Electroconvulsive Thera

2014
[OCULAR PRESSURE, NEUROLEPTIC AGENTS AND PARKINSONIAN STATES].
    Bulletins et memoires de la Societe francaise d'ophtalmologie, 1963, Volume: 76

    Topics: Antipsychotic Agents; Chlorpromazine; Haloperidol; Intraocular Pressure; Methotrimeprazine; Parkinso

1963
[Action of several neuroleptics and diazepam on the hydrodynamics of the eye in healthy people and glaucoma patients].
    Klinika oczna, 1983, Volume: 85, Issue:7

    Topics: Adult; Antipsychotic Agents; Chlorprothixene; Diazepam; Droperidol; Fluspirilene; Glaucoma; Haloperi

1983
Treatment of ocular hypertension and glaucoma with dopamine antagonists.
    Ophthalmic research, 1984, Volume: 16, Issue:3

    Topics: Animals; Antipsychotic Agents; Butyrophenones; Dopamine Antagonists; Female; Glaucoma; Guinea Pigs;

1984
Effects of melatonin and haloperidol given via vortex vein on the intraocular pressure.
    Ophthalmic research, 1993, Volume: 25, Issue:1

    Topics: Analgesics; Animals; Ciliary Body; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Haloper

1993
Evaluation of haloperidol, a dopamine antagonist, on intraocular pressure in experimental glaucoma.
    Indian journal of experimental biology, 1996, Volume: 34, Issue:6

    Topics: Animals; Dopamine Antagonists; Evaluation Studies as Topic; Female; Glaucoma; Haloperidol; Intraocul

1996
Effect of haloperidol, a dopamine antagonist on aqueous humour dynamics in experimental glaucoma.
    Indian journal of experimental biology, 1996, Volume: 34, Issue:11

    Topics: Animals; Aqueous Humor; Dopamine Antagonists; Female; Glaucoma; Haloperidol; Intraocular Pressure; M

1996
The effect of dopamine on the intraocular pressure and pupil of the rabbit eye.
    Investigative ophthalmology, 1976, Volume: 15, Issue:5

    Topics: Administration, Topical; Animals; Denervation; Dopamine; Dose-Response Relationship, Drug; Ganglia,

1976
Effects of dopamine agonist, bromocriptine, and some dopamine antagonists on ocular blood flow.
    Journal of ocular pharmacology, 1992,Winter, Volume: 8, Issue:4

    Topics: Animals; Blood Flow Velocity; Bromocriptine; Disease Models, Animal; Domperidone; Dopamine Antagonis

1992
[An experimental study of the ocular hypotensive action of dopaminergic antagonists].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 1989, Volume: 25, Issue:3

    Topics: Animals; Dopamine Antagonists; Female; Haloperidol; Intraocular Pressure; Male; Pilocarpine; Rabbits

1989
Effects of antiglaucoma drugs on the blood flow in rabbit eyes.
    Ophthalmic research, 1986, Volume: 18, Issue:5

    Topics: Animals; Blood Flow Velocity; Butyrophenones; Drug Evaluation, Preclinical; Eye; Glaucoma; Haloperid

1986
The influence of drugs involved in general anaesthesia and of antihypertensive agents on intraocular and blood pressure in the rabbit.
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1971, Volume: 183, Issue:3

    Topics: Acetazolamide; Anesthesia, General; Anesthetics; Animals; Antihypertensive Agents; Barbiturates; Ben

1971
Novel bioadhesive hyaluronan-itaconic acid crosslinked films for ocular therapy.
    International journal of pharmaceutics, 2013, Oct-15, Volume: 455, Issue:1-2

    Topics: Adhesiveness; Administration, Ophthalmic; Animals; Antihypertensive Agents; Cell Line; Cell Prolifer

2013