haloperidol has been researched along with Injury, Myocardial Reperfusion in 12 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "N-n-butyl haloperidol (F(2)), a novel compound of quaternary ammonium salt derivatives of haloperidol, was reported to antagonize myocardial ischemia/reperfusion injuries." | 3.76 | Cardiac electrophysiological and antiarrhythmic effects of N-n-butyl haloperidol iodide. ( Chen, YC; Gao, FF; Hao, SY; Huang, ZQ; Liu, XP; Shi, GG; Zhang, YM; Zhou, YQ, 2010) |
| "Apomorphine inhibited the increase in carbonylation." | 1.33 | Apomorphine-induced myocardial protection is due to antioxidant and not adrenergic/dopaminergic effects. ( Borman, JB; Houminer, E; Khaliulin, I; Schneider, A; Schwalb, H, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 8 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Y | 5 |
| Liao, H | 1 |
| Zhong, S | 2 |
| Gao, F | 4 |
| Chen, Y | 4 |
| Huang, Z | 1 |
| Lu, S | 1 |
| Sun, T | 1 |
| Wang, B | 3 |
| Li, W | 1 |
| Xu, H | 3 |
| Zheng, F | 2 |
| Shi, G | 5 |
| Lu, B | 1 |
| Gao, FF | 4 |
| Hao, SY | 1 |
| Huang, ZQ | 4 |
| Zhang, YM | 2 |
| Zhou, YQ | 1 |
| Chen, YC | 2 |
| Liu, XP | 2 |
| Shi, GG | 5 |
| Zhou, Y | 1 |
| Guo, F | 2 |
| Wang, J | 1 |
| Cai, W | 1 |
| Zheng, J | 2 |
| Li, HZ | 1 |
| Guo, J | 1 |
| Gao, J | 1 |
| Han, LP | 1 |
| Jiang, CM | 1 |
| Li, HX | 1 |
| Bai, SZ | 1 |
| Zhang, WH | 1 |
| Li, GW | 1 |
| Wang, LN | 1 |
| Li, H | 1 |
| Zhao, YJ | 1 |
| Lin, Y | 1 |
| Tian, Y | 1 |
| Yang, GD | 1 |
| Wang, R | 1 |
| Wu, LY | 1 |
| Yang, BF | 1 |
| Xu, CQ | 1 |
| Xiao, JF | 1 |
| Wang, CY | 2 |
| Huang, YP | 1 |
| Shen, JX | 1 |
| Zheng, YS | 2 |
| Huang, Y | 1 |
| Zheng, Y | 1 |
| Zheng, FC | 1 |
| Xia, ZY | 1 |
| Irwin, MG | 1 |
| Li, WQ | 1 |
| Zheng, JH | 2 |
| Liu, B | 2 |
| Khaliulin, I | 1 |
| Schneider, A | 1 |
| Houminer, E | 1 |
| Borman, JB | 1 |
| Schwalb, H | 1 |
| Tang, Z | 1 |
| Gao, P | 1 |
| Lv, Y | 1 |
| Jia, Q | 1 |
12 other studies available for haloperidol and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Effect of N-n-butyl haloperidol iodide on ROS/JNK/Egr-1 signaling in H9c2 cells after hypoxia/reoxygenation.
Topics: Acetylcysteine; Antipyrine; Cell Hypoxia; Cell Line; Early Growth Response Protein 1; Edaravone; Gen | 2015 |
N-n-butyl haloperidol iodide protects cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy.
Topics: Adenine; Animals; Apoptosis; Autophagy; Cadaverine; Cell Line; Cytoprotection; Dose-Response Relatio | 2015 |
Cardiac electrophysiological and antiarrhythmic effects of N-n-butyl haloperidol iodide.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channels, L-Type; | 2010 |
N-n-butyl haloperidol iodide protects cardiac microvascular endothelial cells from hypoxia/reoxygenation injury by down-regulating Egr-1 expression.
Topics: Animals; Blood Platelets; Cell Adhesion; Cell Hypoxia; Cell Survival; Cells, Cultured; Down-Regulati | 2010 |
Role of dopamine D2 receptors in ischemia/reperfusion induced apoptosis of cultured neonatal rat cardiomyocytes.
Topics: Animals; Animals, Newborn; Apoptosis; Bromocriptine; Calcium; Cells, Cultured; Dopamine D2 Receptor | 2011 |
N-n-butyl haloperidol iodide preserves cardiomyocyte calcium homeostasis during hypoxia/ischemia.
Topics: Aniline Compounds; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Fluorescent | 2011 |
N-n-Butyl haloperidol iodide inhibits the augmented Na+/Ca2+ exchanger currents and L-type Ca2+ current induced by hypoxia/reoxygenation or H2O2 in cardiomyocytes.
Topics: Animals; Calcium Channels, L-Type; Cell Hypoxia; Haloperidol; Hydrogen Peroxide; Male; Myocardial Re | 2012 |
Effects of N-n-butyl haloperidol iodide on the rat myocardial sarcoplasmic reticulum Ca(2+)-ATPase during ischemia/reperfusion.
Topics: Animals; Cardiotonic Agents; Haloperidol; In Vitro Techniques; Male; Microscopy, Electron, Transmiss | 2012 |
Effects of N-n-butyl haloperidol iodide on rat myocardial ischemia and reperfusion injury and L-type calcium current.
Topics: Animals; Calcium Channels, L-Type; Cardiotonic Agents; Haloperidol; Microscopy, Electron; Myocardial | 2003 |
Protective effects of N-n-butyl haloperidol iodide on myocardial ischemia-reperfusion injury in rabbits.
Topics: Animals; Coronary Vessels; Dose-Response Relationship, Drug; Haloperidol; Hemodynamics; Malondialdeh | 2004 |
Apomorphine-induced myocardial protection is due to antioxidant and not adrenergic/dopaminergic effects.
Topics: Adrenergic Agents; Animals; Antioxidants; Apomorphine; Dopamine Agents; Electrophoresis, Polyacrylam | 2006 |
The protective effects of N-n-butyl haloperidol iodide on myocardial ischemia-reperfusion injury in rats by inhibiting Egr-1 overexpression.
Topics: Animals; Base Sequence; Cells, Cultured; Early Growth Response Protein 1; Gene Expression Regulation | 2007 |