haloperidol has been researched along with Inflammation in 38 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with schizophrenia were randomized to monotherapy with risperidone, olanzapine, quetiapine, aripiprazole, ziprasidone, perphenazine or haloperidol in a 6-week pharmacological trial." | 6.23 | The Role of Total White Blood Cell Count in Antipsychotic Treatment for Patients with Schizophrenia. ( Chen, Q; Coid, J; Deng, W; Guo, W; Li, K; Li, L; Li, T; Lu, T; Lv, L; Ma, X; Tan, L; Tan, Q; Tao, S; Wang, C; Wang, L; Wang, Q; Wei, W; Yan, H; Yang, F; Yang, G; Yang, J; Yue, W; Zhang, D; Zhang, F; Zhang, H; Zhang, Y; Zhao, L, 2024) |
| "Haloperidol treatment for 21 days impaired muscle co-ordination, motor activity and grip strength with an increased in orofacial dyskinetic movements." | 5.43 | Beneficial effects of lycopene against haloperidol induced orofacial dyskinesia in rats: Possible neurotransmitters and neuroinflammation modulation. ( Datta, S; Deshmukh, R; Jamwal, S; Kumar, P, 2016) |
| "The effect of course treatment with neuroleptic haloperidol on the inflammatory response and state of the connective tissue in the lungs of C57Bl/6 mice was studied on the model of toxic pulmonary fibrosis induced by intratracheal administration of bleomycin." | 3.78 | Antifibrotic and anti-inflammatory activity of a neuroleptic drug on the model of pulmonary fibrosis. ( Andreeva, TV; Dygai, AM; Ermolaeva, LA; Khmelevskaya, ES; Krupin, VA; Pershina, OV; Reztsova, AM; Skurikhin, EG; Stepanova, IE, 2012) |
| "Mice treated with haloperidol showed an increase in microglial activation and inflammatory mediators in the striatum." | 1.48 | Cannabidiol prevents haloperidol-induced vacuos chewing movements and inflammatory changes in mice via PPARγ receptors. ( Cunha, TM; Del Bel, EA; Guimarães, FS; Prado, DS; Raisman-Vozari, R; Sepulveda-Diaz, JE; Sonego, AB; Tirapelli, CR; Vale, GT, 2018) |
| "Haloperidol treatment for 21 days impaired muscle co-ordination, motor activity and grip strength with an increased in orofacial dyskinetic movements." | 1.43 | Beneficial effects of lycopene against haloperidol induced orofacial dyskinesia in rats: Possible neurotransmitters and neuroinflammation modulation. ( Datta, S; Deshmukh, R; Jamwal, S; Kumar, P, 2016) |
| " The present study investigates the molecular etiology of haloperidol neurotoxicity and the role of curcumin, a well-known anti-oxidant, in ameliorating these adverse effects." | 1.37 | Protective effect of curcumin and its combination with piperine (bioavailability enhancer) against haloperidol-associated neurotoxicity: cellular and neurochemical evidence. ( Bishnoi, M; Chopra, K; Kulkarni, SK; Rongzhu, L, 2011) |
| "Three cases of hemichorea-hemiballismus (HC-HB) associated with nonketotic hyperglycemia were reported." | 1.35 | Hemichorea-hemiballismus associated with nonketotic hyperglycemia: a possible role of inflammation. ( Deng, BQ; Wang, JH; Wang, ZK; Wu, T; Zhang, P; Zhang, YW, 2009) |
| "Inflammation was not a prominent tissue response for any of the test materials, nor was a foreign body giant cell response." | 1.28 | Tissue responses to Hydron, assessed by intramuscular implantation. ( Chau, KK; Heijkoop, PS; Heithersay, GS; Reid, RJ; Wilson, DF, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (13.16) | 18.7374 |
| 1990's | 2 (5.26) | 18.2507 |
| 2000's | 5 (13.16) | 29.6817 |
| 2010's | 21 (55.26) | 24.3611 |
| 2020's | 5 (13.16) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Vivier, D | 1 |
| Bennis, K | 1 |
| Lesage, F | 1 |
| Ducki, S | 1 |
| Zhang, Y | 1 |
| Tao, S | 1 |
| Coid, J | 1 |
| Wei, W | 1 |
| Wang, Q | 1 |
| Yue, W | 1 |
| Yan, H | 1 |
| Tan, L | 1 |
| Chen, Q | 1 |
| Yang, G | 1 |
| Lu, T | 1 |
| Wang, L | 1 |
| Zhang, F | 1 |
| Yang, J | 1 |
| Li, K | 1 |
| Lv, L | 1 |
| Tan, Q | 1 |
| Zhang, H | 1 |
| Ma, X | 2 |
| Yang, F | 1 |
| Li, L | 1 |
| Wang, C | 1 |
| Zhao, L | 1 |
| Deng, W | 1 |
| Guo, W | 1 |
| Zhang, D | 1 |
| Li, T | 1 |
| Zaidi, AA | 1 |
| Khan, MA | 1 |
| Shahreyar, ZA | 1 |
| Ahmed, H | 1 |
| Patergnani, S | 1 |
| Bonora, M | 1 |
| Ingusci, S | 1 |
| Previati, M | 1 |
| Marchi, S | 1 |
| Zucchini, S | 1 |
| Perrone, M | 1 |
| Wieckowski, MR | 1 |
| Castellazzi, M | 1 |
| Pugliatti, M | 1 |
| Giorgi, C | 1 |
| Simonato, M | 1 |
| Pinton, P | 1 |
| Obuchowicz, E | 1 |
| Bielecka-Wajdman, AM | 1 |
| Paul-Samojedny, M | 1 |
| Nowacka, M | 1 |
| Calevro, A | 1 |
| Cotel, MC | 1 |
| Natesan, S | 1 |
| Modo, M | 1 |
| Vernon, AC | 1 |
| Mondelli, V | 1 |
| Sonego, AB | 1 |
| Prado, DS | 1 |
| Vale, GT | 1 |
| Sepulveda-Diaz, JE | 1 |
| Cunha, TM | 1 |
| Tirapelli, CR | 1 |
| Del Bel, EA | 1 |
| Raisman-Vozari, R | 1 |
| Guimarães, FS | 1 |
| Cheremnykh, EG | 1 |
| Ivanov, PA | 1 |
| Sokolov, OY | 1 |
| Prokhorova, TA | 1 |
| Tereshkina, EB | 1 |
| Baymeeva, NV | 1 |
| Miroshnichenko, II | 1 |
| Kost, NV | 1 |
| Dygai, AM | 2 |
| Skurikhin, EG | 2 |
| Ermakova, NN | 1 |
| Pershina, OV | 2 |
| Krupin, VA | 2 |
| Reztsova, AM | 2 |
| Ermolaeva, LA | 2 |
| Khmelevskaya, ES | 2 |
| Stepanova, IE | 2 |
| Artamonov, AV | 1 |
| Bekarev, AA | 1 |
| Madonov, PG | 1 |
| Kinsht, DN | 1 |
| Goldberg, VE | 1 |
| Semiglazova, TA | 1 |
| da Cruz Jung, IE | 1 |
| Machado, AK | 1 |
| da Cruz, IB | 1 |
| Barbisan, F | 1 |
| Azzolin, VF | 1 |
| Duarte, T | 1 |
| Duarte, MM | 1 |
| do Prado-Lima, PA | 1 |
| Bochi, GV | 1 |
| Scola, G | 1 |
| Moresco, RN | 1 |
| Datta, S | 1 |
| Jamwal, S | 1 |
| Deshmukh, R | 1 |
| Kumar, P | 1 |
| Yamamoto, S | 1 |
| Ohta, N | 1 |
| Matsumoto, A | 1 |
| Horiguchi, Y | 1 |
| Koide, M | 1 |
| Fujino, Y | 1 |
| Wang, JH | 1 |
| Wu, T | 1 |
| Deng, BQ | 1 |
| Zhang, YW | 1 |
| Zhang, P | 1 |
| Wang, ZK | 1 |
| Victoriano, M | 1 |
| de Beaurepaire, R | 1 |
| Naour, N | 1 |
| Guerre-Millo, M | 1 |
| Quignard-Boulangé, A | 1 |
| Huneau, JF | 1 |
| Mathé, V | 1 |
| Tomé, D | 1 |
| Hermier, D | 1 |
| Bishnoi, M | 1 |
| Chopra, K | 1 |
| Rongzhu, L | 1 |
| Kulkarni, SK | 1 |
| Andreeva, TV | 1 |
| Machado, RA | 1 |
| Constantino, L | 1 |
| Martins, MR | 1 |
| de Albuquerque, IM | 1 |
| Menna-Barreto, S | 1 |
| Streck, E | 1 |
| Quevedo, J | 1 |
| Dal-Pizzol, F | 1 |
| Irvin, W | 1 |
| MacDonald, G | 1 |
| Smith, JK | 1 |
| Kim, WY | 1 |
| de Oliveira, PHC | 1 |
| Gomes Filho, JE | 1 |
| Rodrigues, MJDS | 1 |
| da Silva, CC | 1 |
| Cardoso, CDBM | 1 |
| Cosme daSilva, L | 1 |
| Ervolino, E | 1 |
| Cintra, LTA | 2 |
| Benetti, F | 1 |
| de Azevedo Queiroz, ÍO | 1 |
| Oliveira, PHC | 1 |
| Conti, LC | 1 |
| Azuma, MM | 1 |
| Oliveira, SHP | 1 |
| Keshavarz-Bahaghighat, H | 1 |
| Darwesh, AM | 1 |
| Sosnowski, DK | 1 |
| Seubert, JM | 1 |
| Tavares, CO | 1 |
| Böttcher, DE | 2 |
| Assmann, E | 2 |
| Kopper, PM | 2 |
| de Figueiredo, JA | 1 |
| Grecca, FS | 4 |
| Scarparo, RK | 3 |
| Hoppe, CB | 1 |
| Zhang, W | 1 |
| Peng, B | 1 |
| Bueno, CR | 1 |
| Valentim, D | 1 |
| Marques, VA | 1 |
| Gomes-Filho, JE | 1 |
| Cintra, LT | 1 |
| Jacinto, RC | 1 |
| Dezan-Junior, E | 1 |
| Fachin, EV | 2 |
| Haddad, D | 1 |
| Acasigua, GA | 1 |
| Fossati, AC | 1 |
| Silva-Herzog, D | 1 |
| Ramírez, T | 1 |
| Mora, J | 1 |
| Pozos, AJ | 1 |
| Silva, LA | 1 |
| Silva, RA | 1 |
| Nelson-Filho, P | 1 |
| Giovanini, AF | 1 |
| Leonardi, DP | 1 |
| Baratto-Filho, F | 1 |
| Vlença, PC | 1 |
| Moresca, RC | 1 |
| Moro, A | 1 |
| Schramm, CA | 1 |
| Lee, DH | 1 |
| Kim, NR | 1 |
| Lim, BS | 1 |
| Lee, YK | 1 |
| Hwang, KK | 1 |
| Yang, HC | 1 |
| Koudelka, BM | 1 |
| Nelson, JF | 1 |
| Webb, JG | 1 |
| Berglundh, T | 1 |
| Thilander, B | 1 |
| Sagne, S | 1 |
| Reid, RJ | 1 |
| Wilson, DF | 1 |
| Chau, KK | 1 |
| Heithersay, GS | 1 |
| Heijkoop, PS | 1 |
| Browne, RM | 2 |
| Friend, LA | 2 |
| Erausquin, J | 1 |
| Muruzábal, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Incidence of Postoperative Pain After Using Different Types of Sealers (A Randomized Clinical Trial)[NCT05841290] | 40 participants (Anticipated) | Interventional | 2023-05-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for haloperidol and Inflammation
| Article | Year |
|---|---|
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Struc | 2016 |
Mitochondrial Dysfunction and Inflammaging in Heart Failure: Novel Roles of CYP-Derived Epoxylipids.
Topics: Animals; Cardiovascular Diseases; Epoxy Resins; Fatty Acids, Unsaturated; Heart Failure; Humans; Imm | 2020 |
1 trial available for haloperidol and Inflammation
| Article | Year |
|---|---|
The Role of Total White Blood Cell Count in Antipsychotic Treatment for Patients with Schizophrenia.
Topics: Antipsychotic Agents; Benzodiazepines; Glucose; Haloperidol; Humans; Inflammation; Olanzapine; Perph | 2024 |
35 other studies available for haloperidol and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Lauric acid: Its role in behavioral modulation, neuro-inflammatory and oxidative stress markers in haloperidol induced Parkinson's disease.
Topics: Animals; Antioxidants; Biomarkers; Corpus Striatum; Cytokines; Haloperidol; Inflammation; Lauric Aci | 2020 |
Antipsychotic drugs counteract autophagy and mitophagy in multiple sclerosis.
Topics: Animals; Antipsychotic Agents; Autophagy; Autophagy-Related Proteins; Axons; Biomarkers; Clozapine; | 2021 |
Different influence of antipsychotics on the balance between pro- and anti-inflammatory cytokines depends on glia activation: An in vitro study.
Topics: Animals; Antipsychotic Agents; Cell Differentiation; Cell Survival; Cells, Cultured; Chlorpromazine; | 2017 |
Effects of chronic antipsychotic drug exposure on the expression of Translocator Protein and inflammatory markers in rat adipose tissue.
Topics: Adipose Tissue; Adiposity; Animals; Antigens, Differentiation; Antipsychotic Agents; Biomarkers; Car | 2018 |
Cannabidiol prevents haloperidol-induced vacuos chewing movements and inflammatory changes in mice via PPARγ receptors.
Topics: Animals; Antioxidants; Antipsychotic Agents; Behavior, Animal; Brain; Cannabidiol; Corpus Striatum; | 2018 |
Haloperidol Reduces the Activity of Complement and Induces the Anti-Inflammatory Transformation of Peritoneal Macrophages in Rats.
Topics: Animals; Complement Activation; Glutathione; Glutathione Reductase; Glutathione Transferase; Haloper | 2019 |
Antifibrotic effect of combined treatment with neuroleptic drug and immobilized hyaluronidase in pulmonary fibrosis.
Topics: Animals; Antipsychotic Agents; Bleomycin; Capillaries; Collagen; Connective Tissue; Drug Therapy, Co | 2013 |
Haloperidol and Risperidone at high concentrations activate an in vitro inflammatory response of RAW 264.7 macrophage cells by induction of apoptosis and modification of cytokine levels.
Topics: Animals; Antipsychotic Agents; Apoptosis; Cell Survival; Cytokines; Dose-Response Relationship, Drug | 2016 |
Beneficial effects of lycopene against haloperidol induced orofacial dyskinesia in rats: Possible neurotransmitters and neuroinflammation modulation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Antipsychotic Agents; Behavior, Animal; Carotenoids | 2016 |
Haloperidol Suppresses NF-kappaB to Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Response in RAW 264 Cells.
Topics: Animals; B7-1 Antigen; B7-2 Antigen; Cytokines; Female; Haloperidol; Inflammation; Interleukins; Lip | 2016 |
Hemichorea-hemiballismus associated with nonketotic hyperglycemia: a possible role of inflammation.
Topics: Aged, 80 and over; Anti-Dyskinesia Agents; Autoimmune Diseases of the Nervous System; Chorea; Corpus | 2009 |
Olanzapine-induced accumulation of adipose tissue is associated with an inflammatory state.
Topics: Adipose Tissue; Analysis of Variance; Animals; Antipsychotic Agents; Benzodiazepines; Cytokines; Glu | 2010 |
Protective effect of curcumin and its combination with piperine (bioavailability enhancer) against haloperidol-associated neurotoxicity: cellular and neurochemical evidence.
Topics: Alkaloids; Analysis of Variance; Animals; Apoptosis; Behavior, Animal; Benzodioxoles; Caspase 3; Col | 2011 |
Antifibrotic and anti-inflammatory activity of a neuroleptic drug on the model of pulmonary fibrosis.
Topics: Administration, Inhalation; Animals; Antipsychotic Agents; Bleomycin; Cell Differentiation; Connecti | 2012 |
Lack of effect of dopaminergic antagonists in a rodent model of peritoneal sepsis.
Topics: Animals; Biomarkers; Clozapine; Disease Models, Animal; Dopamine Antagonists; Haloperidol; Inflammat | 2007 |
Dexamethasone-induced posterior reversible encephalopathy syndrome.
Topics: Anti-Inflammatory Agents; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Dexamethasone; Dopamine A | 2007 |
Influence of supplement administration of omega-3 on the subcutaneous tissue response of endodontic sealers in Wistar rats.
Topics: Animals; Calcium; Dietary Supplements; Epoxy Resins; Inflammation; Interleukin-6; Materials Testing; | 2022 |
Cytotoxicity and biocompatibility of a new bioceramic endodontic sealer containing calcium hydroxide.
Topics: Aluminum Compounds; Animals; Biocompatible Materials; Bone Cements; Calcium Compounds; Calcium Hydro | 2019 |
Tissue reactions to a new mineral trioxide aggregate-containing endodontic sealer.
Topics: Abscess; Aluminum Compounds; Animals; Biocompatible Materials; Calcium Compounds; Collagen; Drug Com | 2013 |
Evaluation of bone tissue response to a sealer containing mineral trioxide aggregate.
Topics: Aluminum Compounds; Animals; Biocompatible Materials; Bone and Bones; Calcium Compounds; Drug Combin | 2015 |
Tissue reactions after subcutaneous and intraosseous implantation of iRoot SP, MTA and AH Plus.
Topics: Aluminum Compounds; Animals; Biocompatible Materials; Calcium Compounds; Drug Combinations; Epoxy Re | 2015 |
Biocompatibility and biomineralization assessment of bioceramic-, epoxy-, and calcium hydroxide-based sealers.
Topics: Animals; Biocompatible Materials; Calcium Hydroxide; Ceramics; Epoxy Resins; Inflammation; Male; Mat | 2016 |
Analysis of tissue reactions to methacrylate resin-based, epoxy resin-based, and zinc oxide-eugenol endodontic sealers.
Topics: Abscess; Acrylic Resins; Animals; Biocompatible Materials; Composite Resins; Epoxy Resins; Inflammat | 2009 |
Mineral trioxide aggregate-based sealer: analysis of tissue reactions to a new endodontic material.
Topics: Abscess; Aluminum Compounds; Animals; Biocompatible Materials; Calcium Compounds; Collagen; Connecti | 2010 |
Preliminary study of the inflammatory response to subcutaneous implantation of three root canal sealers.
Topics: Animals; Balsams; Calcium Hydroxide; Capillary Permeability; Dental Cements; Drug Combinations; Edem | 2011 |
An endodontic sealer induces a pathological condition when associated with persistent tissue toxicity and presence of myofibroblasts.
Topics: Actins; Animals; Collagen; Epoxy Resins; Fibrosis; Granulation Tissue; Image Processing, Computer-As | 2011 |
Effects of root canal sealers on lipopolysaccharide-induced expression of cyclooxygenase-2 mrna in murine macrophage cells.
Topics: Animals; Bismuth; Calcium Hydroxide; Cell Line; Cell Survival; Cyclooxygenase 2; Drug Combinations; | 2007 |
Denture self-repair: experimental soft tissue response to selected commercial adhesives.
Topics: Acetates; Adhesives; Amines; Animals; Connective Tissue; Cyanoacrylates; Denture Repair; Epoxy Resin | 1980 |
Tissue characteristics of root resorption areas in transplanted maxillary canines.
Topics: Adult; Alveolar Process; Biopsy; Collagen; Coloring Agents; Cuspid; Decalcification Technique; Denta | 1997 |
Tissue responses to Hydron, assessed by intramuscular implantation.
Topics: Animals; Biocompatible Materials; Bismuth; Drug Combinations; Epoxy Resins; Foreign-Body Reaction; G | 1992 |
Acrylic resins.
Topics: Acrylates; Acrylic Resins; Animals; Anti-Infective Agents, Local; Asthma; Copper; Cyanides; Dental A | 1971 |
An investigation into the irritant properties of some root filling materials.
Topics: Animals; Dental Amalgam; Dental Materials; Dental Restoration, Permanent; Epoxy Resins; Inflammation | 1968 |
Tissue reactions to some root filling materials implanted in the bone of rabbits.
Topics: Animals; Bone and Bones; Dental Amalgam; Dental Materials; Epoxy Resins; Inflammation; Necrosis; Pol | 1969 |
Tissue reaction to root canal fillings with plastic cements.
Topics: Adhesiveness; Animals; Dental Cementum; Dental Materials; Dentin; Epoxy Resins; Inflammation; Necros | 1970 |