Page last updated: 2024-10-28

haloperidol and Hyperactivity, Motor

haloperidol has been researched along with Hyperactivity, Motor in 79 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Research Excerpts

ExcerptRelevanceReference
" Evaluation of (+)-22a in animal models of schizophrenia-related behaviors revealed that it had a desirable activity profile, as it reduced d-amphetamine-stimulated hyperlocomotion in the open field test, it restored d-amphetamine-disrupted prepulse inhibition, it induced cognitive improvements in the novel object recognition memory test in NR1-KD animals, and it produced very little catalepsy relative to haloperidol."3.83Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models. ( Cheng, J; Giguere, PM; Huang, XP; Kozikowski, AP; McCorvy, JD; Pogorelov, VM; Rodriguiz, RM; Roth, BL; Schmerberg, CM; Wetsel, WC; Zhu, H, 2016)
"Activated lipid peroxidation observed in brain homogenates in experimental choreoid hyperkinesis and bemegride epilepsy can be arrested by antioxidant pretreatment."3.69[The role of lipid peroxidation in the pathogenesis of neuropathological syndromes and in experimental therapy]. ( Aliev, AN; Aliev, MN; Mamedbeĭli, TN; Rzaev, RN, 1994)
"Either L-dopa, in combination with 1-alpha-methyldopa hydrazine (MK-486), or 1-(2''-pyrimidyl)-4-piperonylpiperazine, an agent that stimulates dopamine receptors, relieves surgically induced tremor in monkeys and concomitantly evokes involuntary movements."3.65Tremor and involuntary movements in monkeys: effect of L-dopa and of a dopamine receptor stimulating agent. ( Anagnoste, B; Battista, AF; Fuxe, K; Goldstein, M; Ohmoto, T, 1973)
"Treatment with haloperidol or LY379268 normalized novelty-induced locomotor hyperactivity in GLAST KO."1.35Loss of glial glutamate and aspartate transporter (excitatory amino acid transporter 1) causes locomotor hyperactivity and exaggerated responses to psychotomimetics: rescue by haloperidol and metabotropic glutamate 2/3 agonist. ( Heilig, M; Holmes, A; Karlsson, RM; Tanaka, K, 2008)
"Aripiprazole is an atypical antipsychotic that acts as a partial agonist at the dopamine D(2) receptor."1.35Aripiprazole, an atypical antipsychotic, prevents the motor hyperactivity induced by psychotomimetics and psychostimulants in mice. ( Guimarães, FS; Leite, JV; Moreira, FA, 2008)
" In addition the home cage behaviour of mice administered with the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) using an acute dosing regimen was also investigated."1.33Further validation of LABORAS using various dopaminergic manipulations in mice including MPTP-induced nigro-striatal degeneration. ( Billinton, A; Brown, M; Chapman, H; Quinn, LP; Stean, TO; Upton, N; Vidgeon-Hart, M; Virley, DJ, 2006)
" Thus, for example, NT69L after five daily injections at a fixed dosage was as effective at reversing cocaine-induced hyperactivity as after the first injection."1.32Selective tolerance to the hypothermic and anticataleptic effects of a neurotensin analog that crosses the blood-brain barrier. ( Boules, M; Fauq, A; McCormick, D; McMahon, B; Richelson, E; Stewart, J; Wang, R; Warrington, L; Yerbury, S, 2003)
" While typical antipsychotics are often switched to atypical agents when adverse effects become limiting, there is little preclinical information to support this strategy, both in terms of efficacy and side effects."1.32Combined treatment of quetiapine with haloperidol in animal models of antipsychotic effect and extrapyramidal side effects: comparison with risperidone and chlorpromazine. ( Matsuoka, N; Mutoh, S; Shirakawa, K; Tada, M, 2004)
"When haloperidol 2 mg/kg was administered i."1.31Dopaminergic neurotransmission triggers ischemia-induced hyperactivity in Mongolian gerbils. ( Araki, H; Futagami, K; Gomita, Y; Kawasaki, H; Yamamoto, T, 2001)
"A model of hyperkinesia in the rat, exaggerated paw treading triggered by oral sensory stimulation, has been reported previously to result from lesions of the globus pallidus or ventral pallidum/substantia innominata."1.30Haloperidol decreases hyperkinetic paw treading induced by globus pallidus lesions in the rat. ( Berridge, KC; Cromwell, HC, 1997)
"Gilles de la Tourette syndrome is frequently associated with symptoms characteristic of hyperactivity and often goes unrecognized for long periods of time."1.26Deleterious effects of drugs used for hyperactivity on patients with Gilles de la Tourette syndrome. ( Sleator, EK, 1980)
"Treatment with haloperidol in all patients and with dipropylacetic acid in three patients did not appear to modify the CSF, HVA, and 5HIAA concentrations, the plasma DBH activity, or the DA uptake."1.26Biochemical aspects of Huntington's chorea. ( Algeri, S; Branciforti, A; Calderini, G; Caraceni, T; Consolazione, A; Dall'olio, A; Girotti, F; Morselli, PL; Riva, E; Spreafico, R, 1977)
"Gilles de la Tourette's syndrome was independently ascertained in two male cousins once removed."1.26Gilles de la Tourette's syndrome. Familial occurrence and precipitation by methylphenidate therapy. ( Cohen, NL; Friedhoff, AJ; Pollack, MA, 1977)
"We conclude that phenytoin induced hyperkinesias reflect a specific effect of phenytoin on an abnormal neural substrate and suggest the presence of an otherwise silent pathological alteration of the corpus striatum."1.26Clinical and experimental studies of phenytoin-induced hyperkinesias. ( Klawans, HL; Koller, WC; Nausieda, PA; Weiner, WJ, 1979)
"The hyperkinesia was antagonized by phenoxybenzamine (an alpha-adrenergic receptor antagonist) and by FLA-63 (a dopamine-beta-hydroxylase inhibitor) but not by haloperidol (a dopamine receptor antagonist)."1.26The hyperkinetic syndrome following long-term haloperidol treatment: involvement of dopamine and noradrenaline. ( Dunstan, R; Jackson, DM; Perrington, A, 1979)

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-199041 (51.90)18.7374
1990's12 (15.19)18.2507
2000's20 (25.32)29.6817
2010's5 (6.33)24.3611
2020's1 (1.27)2.80

Authors

AuthorsStudies
de Paulis, T1
Kumar, Y1
Johansson, L1
Rämsby, S1
Florvall, L1
Hall, H1
Angeby-Möller, K1
Ogren, SO2
Taverne, T1
Diouf, O1
Depreux, P1
Poupaert, JH1
Lesieur, D1
Guardiola-Lemaître, B1
Renard, P1
Rettori, MC1
Caignard, DH1
Pfeiffer, B1
Cheng, J1
Giguere, PM1
Schmerberg, CM1
Pogorelov, VM1
Rodriguiz, RM1
Huang, XP1
Zhu, H1
McCorvy, JD1
Wetsel, WC1
Roth, BL1
Kozikowski, AP1
Lages, YV1
Maisonnette, SS1
Rosseti, FP1
Galvão, BO1
Landeira-Fernandez, J1
Sun, T3
Liu, X1
Li, M3
Boerner, T1
Bygrave, AM1
Chen, J1
Fernando, A1
Jackson, S1
Barkus, C1
Sprengel, R1
Seeburg, PH1
Harrison, PJ1
Gilmour, G1
Bannerman, DM1
Sanderson, DJ1
Karlsson, RM1
Tanaka, K1
Heilig, M1
Holmes, A1
Maehara, S1
Hikichi, H1
Satow, A1
Okuda, S1
Ohta, H1
Hu, G1
van der Staay, FJ1
Pouzet, B2
Mahieu, M1
Nordquist, RE1
Schuurman, T1
Hidaka, N1
Suemaru, K1
Araki, H2
Zhao, C1
Garris, PA1
Budygin, EA1
Phillips, PE1
Venton, BJ1
Robinson, DL1
Bergstrom, BP1
Rebec, GV1
Wightman, RM1
O'Neill, MF1
Heron-Maxwell, C1
Conway, MW1
Monn, JA1
Ornstein, P1
Boules, M1
McMahon, B1
Wang, R1
Warrington, L1
Stewart, J1
Yerbury, S1
Fauq, A1
McCormick, D1
Richelson, E1
Tada, M1
Shirakawa, K1
Matsuoka, N1
Mutoh, S1
Coppola, G1
Morelli, E1
Bravaccio, C1
Federico, R1
Gritti, A1
Nilsson, M2
Carlsson, A2
Markinhuhta, KR1
Sonesson, C1
Pettersson, F1
Gullme, M1
Carlsson, ML2
Lautar, SL1
Rojas, C1
Slusher, BS1
Wozniak, KM1
Wu, Y1
Thomas, AG1
Waldon, D1
Li, W1
Ferraris, D1
Belyakov, S1
Dall'Igna, OP1
Tort, AB1
Souza, DO1
Lara, DR1
Fredriksson, A1
Eriksson, P1
Archer, T1
Quinn, LP1
Stean, TO1
Chapman, H1
Brown, M1
Vidgeon-Hart, M1
Upton, N1
Billinton, A1
Virley, DJ1
Leite, JV1
Guimarães, FS1
Moreira, FA1
Schiele, B1
Cools, AR2
van Rossum, JM1
Lin, MT1
Chan, HK1
Chen, CF1
Teh, GW1
Ushijima, I1
Yamada, K1
Noda, Y1
Furukawa, T1
Morgenstern, R1
Fink, H1
Oelssner, W1
Clementi, G1
Prato, A1
Bernardini, R1
Nicoletti, F1
Patti, F1
De Simone, D1
Scapagnini, U1
Castillo, J1
Castro, A1
Dapena, D1
Arias, M1
Colell, S1
Lema, M1
Noya, M1
Schechter, MD1
Concannon, JT1
Sleator, EK1
Köhler, C1
Haglund, L1
Angeby, T1
Aliev, MN1
Rzaev, RN1
Mamedbeĭli, TN1
Aliev, AN1
Gay, J1
Losa, JE1
Iglesias-Osma, C1
Ortín, A1
Iakimovskiĭ, AF1
Ouagazzal, A1
Amalric, M1
Fang, J1
Cromwell, HC1
Berridge, KC1
Furuya, Y1
Kagaya, T1
Nishizawa, Y1
Ogura, H1
Ninan, I1
Kulkarni, SK1
Martin, P1
Sorensen, SM1
Waters, S1
Waters, N1
Maj, J1
Rogóz, Z1
Skuza, G1
Bast, T1
Zhang, WN1
Heidbreder, C1
Feldon, J1
Andersen, MP1
Yamamoto, T1
Futagami, K1
Kawasaki, H1
Gomita, Y1
Stalman, SL1
Turrone, P1
Remington, G1
Nobrega, JN1
Winsberg, BG1
Yepes, LE1
Bialer, I1
Heath, A1
Caraceni, T1
Calderini, G1
Consolazione, A1
Riva, E1
Algeri, S1
Girotti, F1
Spreafico, R1
Branciforti, A1
Dall'olio, A1
Morselli, PL1
Pollack, MA1
Cohen, NL1
Friedhoff, AJ1
Badalian, LO1
Skvortsov, IA1
Kamennykh, LN1
Dadali, EL1
Temin, PA1
Feinberg, M1
Carroll, BJ1
Oldham, AJ2
Nausieda, PA1
Koller, WC1
Weiner, WJ1
Klawans, HL1
Kuczenski, R1
Schmidt, D1
Leith, N1
Pert, A1
Sivit, C1
Langlais, PJ1
Gabay, S1
Jackson, DM1
Dunstan, R1
Perrington, A1
Werry, JS4
Aman, MG4
Lampen, E1
Dowrick, PW1
Raeburn, JM1
Barker, P1
Malyshev, IuI1
Grabowski, SW1
Kivalo, E1
Weckman, N1
Ott, J1
Müller, E1
Heidrich, R1
Snyder, SH1
Taylor, KM1
Coyle, JT1
Meyerhoff, JL1
Arushanian, EB1
Golden, GS1
Goldstein, M1
Battista, AF1
Ohmoto, T1
Anagnoste, B1
Fuxe, K1
Nagyová, H1
Novotný, V1
Tewfik, GI1
Jain, VK1
Harcup, M1
Magowan, S1
Bott, M1
Gurovich, IIa1
Fleĭs, EP1

Reviews

4 reviews available for haloperidol and Hyperactivity, Motor

ArticleYear
Multiple receptors for brain dopamine in behavior regulation: concept of dopamine-E and dopamine-I receptors.
    Life sciences, 1980, Oct-06, Volume: 27, Issue:14

    Topics: Adenylyl Cyclases; Animals; Apomorphine; Behavior, Animal; Brain; Cats; Corpus Striatum; Dextroamphe

1980
The vacuous chewing movement (VCM) model of tardive dyskinesia revisited: is there a relationship to dopamine D(2) receptor occupancy?
    Neuroscience and biobehavioral reviews, 2002, Volume: 26, Issue:3

    Topics: Animals; Antipsychotic Agents; Dopamine Antagonists; Dyskinesia, Drug-Induced; Haloperidol; Humans;

2002
Psychiatric drug treatment in children.
    The Journal of the Maine Medical Association, 1979, Volume: 70, Issue:5

    Topics: Adolescent; Amphetamines; Antipsychotic Agents; Anxiety; Autistic Disorder; Behavior Therapy; Child;

1979
[The role of dopamine in the physiology and pathology of the basal ganglia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1972, Volume: 72, Issue:4

    Topics: Basal Ganglia; Brain; Caudate Nucleus; Chlorpromazine; Corpus Striatum; Dihydroxyphenylalanine; Dopa

1972

Trials

6 trials available for haloperidol and Hyperactivity, Motor

ArticleYear
Effects of dopamine agonists and antagonists in Tourette's disease.
    Archives of general psychiatry, 1979, Volume: 36, Issue:9

    Topics: Adolescent; Adult; Amphetamine; Apomorphine; Child; Clinical Trials as Topic; Dextroamphetamine; Dop

1979
Haloperidol and methylphenidate in hyperactive children.
    Acta paedopsychiatrica, 1976, Volume: 42, Issue:1

    Topics: Child; Child, Preschool; Clinical Trials as Topic; Cognition; Dose-Response Relationship, Drug; Drug

1976
Methylphenidate and haloperidol in children. Effects on attention, memory, and activity.
    Archives of general psychiatry, 1975, Volume: 32, Issue:6

    Topics: Aggression; Attention; Child; Child, Preschool; Clinical Trials as Topic; Cognition; Dose-Response R

1975
The effects of methylphenidate and haloperidol on the heart rate and blood pressure of hyperactive children with special reference to time of action.
    Psychopharmacologia, 1975, Aug-21, Volume: 43, Issue:2

    Topics: Analysis of Variance; Blood Pressure; Child; Clinical Trials as Topic; Digestion; Female; Haloperido

1975
Safety and effectiveness of haloperidol for mentally retarded behaviorally disordered and hyperkinetic patients.
    Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:11

    Topics: Adolescent; Adult; Affective Symptoms; Aged; Benztropine; Child; Clinical Trials as Topic; Female; H

1973
Effectiveness of various tranquilisers in the management of senile restlessness.
    Gerontologia clinica, 1970, Volume: 12, Issue:6

    Topics: Aged; Carbamates; Chlorpromazine; Clinical Trials as Topic; Dementia; Female; Haloperidol; Humans; H

1970

Other Studies

69 other studies available for haloperidol and Hyperactivity, Motor

ArticleYear
Potential neuroleptic agents. 3. Chemistry and antidopaminergic properties of substituted 6-methoxysalicylamides.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:9

    Topics: Animals; Apomorphine; Benzamides; Chemical Phenomena; Chemistry; Corpus Striatum; Dopamine Antagonis

1985
Novel benzothiazolin-2-one and benzoxazin-3-one arylpiperazine derivatives with mixed 5HT1A/D2 affinity as potential atypical antipsychotics.
    Journal of medicinal chemistry, 1998, Jun-04, Volume: 41, Issue:12

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Catalepsy; Cattle; Corpus Striatum; Dopamine Agen

1998
Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models.
    Journal of medicinal chemistry, 2016, Jan-28, Volume: 59, Issue:2

    Topics: Animals; Brain; Catalepsy; Central Nervous System Stimulants; Cognition; Dextroamphetamine; Drug Des

2016
Haloperidol and methylphenidate alter motor behavior and responses to conditioned fear of Carioca Low-conditioned Freezing rats.
    Pharmacology, biochemistry, and behavior, 2021, Volume: 211

    Topics: Animals; Anxiety; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Conditioning, Psy

2021
Effect of environmental cues on the behavioral efficacy of haloperidol, olanzapine, and clozapine in rats.
    Behavioural pharmacology, 2014, Volume: 25, Issue:4

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Cues; Drug Tolerance; Environment; Excita

2014
The group II metabotropic glutamate receptor agonist LY354740 and the D2 receptor antagonist haloperidol reduce locomotor hyperactivity but fail to rescue spatial working memory in GluA1 knockout mice.
    The European journal of neuroscience, 2017, Volume: 45, Issue:7

    Topics: Animals; Bridged Bicyclo Compounds; Dopamine Antagonists; Excitatory Amino Acid Agonists; Female; Ha

2017
Loss of glial glutamate and aspartate transporter (excitatory amino acid transporter 1) causes locomotor hyperactivity and exaggerated responses to psychotomimetics: rescue by haloperidol and metabotropic glutamate 2/3 agonist.
    Biological psychiatry, 2008, Nov-01, Volume: 64, Issue:9

    Topics: Amino Acids; Analysis of Variance; Animals; Anti-Dyskinesia Agents; Behavior, Animal; Bridged Bicycl

2008
Antipsychotic property of a muscarinic receptor agonist in animal models for schizophrenia.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 91, Issue:1

    Topics: Animals; Antipsychotic Agents; Central Nervous System Stimulants; Clozapine; Dose-Response Relations

2008
Repeated antipsychotic treatment progressively potentiates inhibition on phencyclidine-induced hyperlocomotion, but attenuates inhibition on amphetamine-induced hyperlocomotion: relevance to animal models of antipsychotic drugs.
    European journal of pharmacology, 2009, Jan-14, Volume: 602, Issue:2-3

    Topics: Amphetamine; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Clozapine; Disease Models, Animal;

2009
The d-amphetamine-treated Göttingen miniature pig: an animal model for assessing behavioral effects of antipsychotics.
    Psychopharmacology, 2009, Volume: 206, Issue:4

    Topics: Animals; Antipsychotic Agents; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship

2009
Serotonin-dopamine antagonism ameliorates impairments of spontaneous alternation and locomotor hyperactivity induced by repeated electroconvulsive seizures in rats.
    Epilepsy research, 2010, Volume: 90, Issue:3

    Topics: Analysis of Variance; Animals; Behavior, Animal; Dopamine Antagonists; Electroshock; Haloperidol; Hy

2010
Neural basis of the potentiated inhibition of repeated haloperidol and clozapine treatment on the phencyclidine-induced hyperlocomotion.
    Progress in neuro-psychopharmacology & biological psychiatry, 2012, Aug-07, Volume: 38, Issue:2

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Brain; Clozapine; Haloperidol; Hyperkinesis; Male;

2012
A role for presynaptic mechanisms in the actions of nomifensine and haloperidol.
    Neuroscience, 2003, Volume: 118, Issue:3

    Topics: Animals; Autoreceptors; Brain; Catalepsy; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane T

2003
Group II metabotropic glutamate receptor antagonists LY341495 and LY366457 increase locomotor activity in mice.
    Neuropharmacology, 2003, Volume: 45, Issue:5

    Topics: Amino Acids; Animals; Benzazepines; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relatio

2003
Selective tolerance to the hypothermic and anticataleptic effects of a neurotensin analog that crosses the blood-brain barrier.
    Brain research, 2003, Oct-10, Volume: 987, Issue:1

    Topics: Amphetamine; Animals; Behavior, Animal; Blood Glucose; Blood-Brain Barrier; Body Temperature; Brain;

2003
Combined treatment of quetiapine with haloperidol in animal models of antipsychotic effect and extrapyramidal side effects: comparison with risperidone and chlorpromazine.
    Psychopharmacology, 2004, Volume: 176, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Oral; Animals; Antipsychotic Agents; Basal G

2004
Unusual compulsive motor activity during treatment with clothiapine in a mentally retarded adolescent.
    Brain & development, 2004, Volume: 26, Issue:6

    Topics: Adolescent; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Compulsive Be

2004
The dopaminergic stabiliser ACR16 counteracts the behavioural primitivization induced by the NMDA receptor antagonist MK-801 in mice: implications for cognition.
    Progress in neuro-psychopharmacology & biological psychiatry, 2004, Volume: 28, Issue:4

    Topics: Animals; Autistic Disorder; Behavior, Animal; Cognition; Dizocilpine Maleate; Dopamine Antagonists;

2004
DPP IV inhibitor blocks mescaline-induced scratching and amphetamine-induced hyperactivity in mice.
    Brain research, 2005, Jun-28, Volume: 1048, Issue:1-2

    Topics: Amphetamine; Animals; Aza Compounds; Azetidines; Behavior, Animal; Diabetes Mellitus; Dipeptidyl-Pep

2005
Cinnarizine has an atypical antipsychotic profile in animal models of psychosis.
    Journal of psychopharmacology (Oxford, England), 2005, Volume: 19, Issue:4

    Topics: Amphetamine; Animals; Antipsychotic Agents; Calcium Channel Blockers; Catalepsy; Central Nervous Sys

2005
Postnatal iron-induced motor behaviour alterations following chronic neuroleptic administration in mice.
    Journal of neural transmission (Vienna, Austria : 1996), 2006, Volume: 113, Issue:2

    Topics: Animals; Antipsychotic Agents; Apomorphine; Basal Ganglia; Clozapine; Dopamine Agonists; Drug Intera

2006
Further validation of LABORAS using various dopaminergic manipulations in mice including MPTP-induced nigro-striatal degeneration.
    Journal of neuroscience methods, 2006, Sep-30, Volume: 156, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Animals; Apomorphine; Automation; Behavio

2006
Aripiprazole, an atypical antipsychotic, prevents the motor hyperactivity induced by psychotomimetics and psychostimulants in mice.
    European journal of pharmacology, 2008, Jan-14, Volume: 578, Issue:2-3

    Topics: Amphetamine; Animals; Antipsychotic Agents; Aripiprazole; Catalepsy; Central Nervous System Stimulan

2008
[Therapeutic profile of haloperidol].
    Acta psiquiatrica y psicologica de America latina, 1980, Volume: 26, Issue:1

    Topics: Agranulocytosis; Antipsychotic Agents; Chemical and Drug Induced Liver Injury; Drug Eruptions; Drug

1980
Involvement of both opiate and catecholaminergic receptors in the behavioural excitation provoked by thyrotropin-releasing hormone: comparisons with amphetamine.
    Neuropharmacology, 1983, Volume: 22, Issue:4

    Topics: Amphetamine; Animals; Behavior, Animal; Haloperidol; Humans; Hyperkinesis; Male; Naloxone; Propranol

1983
Progressive augmentation of locomotor activity in mice by long-term treatment with thyrotropin releasing hormone.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 270, Issue:1

    Topics: Animals; Apomorphine; Drug Interactions; Haloperidol; Humans; Hyperkinesis; Injections, Subcutaneous

1984
LSD-potentiated apomorphine hypermotility: a model for differentiating antipsychotic drugs.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:1

    Topics: Animals; Apomorphine; Chlorpromazine; Clozapine; Disease Models, Animal; Drug Antagonism; Haloperido

1983
Effects of calcitonin on the brain of aged rats.
    Neurobiology of aging, 1983,Fall, Volume: 4, Issue:3

    Topics: Age Factors; Animals; Apomorphine; Calcitonin; Catalepsy; Drug Synergism; Extrapyramidal Tracts; Hal

1983
[Clinical and electrophysiological study of idiopathic orofacial dystonia (Meige's disease or Brueghel syndrome)].
    Revista clinica espanola, 1984, Apr-30, Volume: 173, Issue:2

    Topics: Dystonia; Electromyography; Facial Expression; Facial Muscles; Female; Haloperidol; Humans; Hyperkin

1984
Haloperidol-induced hyperactivity in neonatal rats: effect of lithium and stimulants.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 16, Issue:1

    Topics: Animals; Animals, Newborn; Dextroamphetamine; Disease Models, Animal; Female; Haloperidol; Humans; H

1982
Deleterious effects of drugs used for hyperactivity on patients with Gilles de la Tourette syndrome.
    Clinical pediatrics, 1980, Volume: 19, Issue:7

    Topics: Child; Haloperidol; Humans; Hyperkinesis; Male; Methylphenidate; Pemoline; Tourette Syndrome

1980
Regional blockade by neuroleptic drugs of in vivo 3H-spiperone binding in the rat brain. Relation to blockade of apomorphine induced hyperactivity and stereotypies.
    Journal of neural transmission, 1981, Volume: 52, Issue:3

    Topics: Animals; Apomorphine; Binding, Competitive; Brain; Butyrophenones; Chlorpromazine; Clozapine; Halope

1981
[The role of lipid peroxidation in the pathogenesis of neuropathological syndromes and in experimental therapy].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1994, Volume: 94, Issue:6

    Topics: Animals; Antioxidants; Bemegride; Brain Chemistry; Chorea; Disease Models, Animal; Drug Evaluation,

1994
[Hemichorea-hemiballismus syndrome worsened by haloperidol].
    Medicina clinica, 1994, Feb-19, Volume: 102, Issue:6

    Topics: Aged; Chorea; Female; Haloperidol; Humans; Hyperkinesis; Syndrome

1994
[The effect of the activation and blockade of the neostriatal dopaminergic system on the hyperkinesis evoked in rats by the intrastriatal administration of picrotoxin].
    Biulleten' eksperimental'noi biologii i meditsiny, 1993, Volume: 116, Issue:7

    Topics: Amphetamine; Animals; Chorea; Haloperidol; Hyperkinesis; Male; Metoclopramide; Microinjections; Myoc

1993
Competitive NMDA receptor antagonists do not produce locomotor hyperactivity by a dopamine-dependent mechanism.
    European journal of pharmacology, 1995, Dec-27, Volume: 294, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Dose-Resp

1995
Hyperactive behavioural effects induced by intranigral infusion of a pyridinium metabolite of haloperidol in rats.
    Canadian journal of physiology and pharmacology, 1996, Volume: 74, Issue:12

    Topics: Animals; Behavior, Animal; Dystonia; Haloperidol; Hyperkinesis; Injections, Intraventricular; Male;

1996
Haloperidol decreases hyperkinetic paw treading induced by globus pallidus lesions in the rat.
    Experimental neurology, 1997, Volume: 145, Issue:1

    Topics: Animals; Behavior, Animal; Dopamine Antagonists; Forelimb; Globus Pallidus; Haloperidol; Hyperkinesi

1997
Differential effects of the strychnine-insensitive glycine site antagonist (+)-HA-966 on the hyperactivity and the disruption of prepulse inhibition induced by phencyclidine in rats.
    Brain research, 1998, Jan-19, Volume: 781, Issue:1-2

    Topics: Animals; Antipsychotic Agents; Apomorphine; Dopamine Agonists; Drug Evaluation, Preclinical; Excitat

1998
Preferential blockade by clozapine of hyperlocomotion induced by non-competitive NMDA antagonist MK-801.
    Indian journal of physiology and pharmacology, 1998, Volume: 42, Issue:3

    Topics: Analysis of Variance; Animals; Antipsychotic Agents; Benzazepines; Clozapine; Dizocilpine Maleate; D

1998
Serotonin: a behaviorally active compound in the caudate nucleus of cats.
    Israel journal of medical sciences, 1973, Volume: 9 Suppl

    Topics: Animals; Athetosis; Autonomic Agents; Behavior, Animal; Carbachol; Cats; Caudate Nucleus; Compulsive

1973
The 5-HT2A receptor antagonist M100907 is more effective in counteracting NMDA antagonist- than dopamine agonist-induced hyperactivity in mice.
    Journal of neural transmission (Vienna, Austria : 1996), 1999, Volume: 106, Issue:2

    Topics: Amphetamine; Animals; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors;

1999
The anticataleptic effect of 7-OH-DPAT: are dopamine D3 receptors involved?
    Journal of neural transmission (Vienna, Austria : 1996), 1999, Volume: 106, Issue:11-12

    Topics: Animals; Antipsychotic Agents; Brain Chemistry; Catalepsy; Dextroamphetamine; Dopamine Agents; Dopam

1999
Hyperactivity and disruption of prepulse inhibition induced by N-methyl-D-aspartate stimulation of the ventral hippocampus and the effects of pretreatment with haloperidol and clozapine.
    Neuroscience, 2001, Volume: 103, Issue:2

    Topics: Animals; Clozapine; Dopamine Antagonists; Excitatory Amino Acid Agonists; Haloperidol; Hippocampus;

2001
Effects of acute versus chronic treatment with typical or atypical antipsychotics on d-amphetamine-induced sensorimotor gating deficits in rats.
    Psychopharmacology, 2001, Volume: 156, Issue:2-3

    Topics: Acoustic Stimulation; Animals; Antipsychotic Agents; Benzodiazepines; Central Nervous System Stimula

2001
Dopaminergic neurotransmission triggers ischemia-induced hyperactivity in Mongolian gerbils.
    Acta medica Okayama, 2001, Volume: 55, Issue:5

    Topics: Animals; Brain Ischemia; Dopamine; Dopamine Antagonists; Gerbillinae; Haloperidol; Hyperkinesis; Inj

2001
Prevention of relapse in schizophrenia.
    The New England journal of medicine, 2002, May-02, Volume: 346, Issue:18

    Topics: Antipsychotic Agents; Haloperidol; Humans; Hyperkinesis; Psychomotor Agitation; Risperidone; Schizop

2002
Pharmacologic management of children with hyperactive/aggressive/inattentive behavior disorders. Suggestions for the pediatrician.
    Clinical pediatrics, 1976, Volume: 15, Issue:5

    Topics: Age Factors; Aggression; Antidepressive Agents, Tricyclic; Attention; Central Nervous System Stimula

1976
Biochemical aspects of Huntington's chorea.
    Journal of neurology, neurosurgery, and psychiatry, 1977, Volume: 40, Issue:6

    Topics: Adult; Age Factors; Blood Platelets; Brain Damage, Chronic; Dopamine; Dopamine beta-Hydroxylase; Fem

1977
Gilles de la Tourette's syndrome. Familial occurrence and precipitation by methylphenidate therapy.
    Archives of neurology, 1977, Volume: 34, Issue:10

    Topics: Adult; Child; Dextroamphetamine; Haloperidol; Humans; Hyperkinesis; Male; Methylphenidate; Pedigree;

1977
[Generalized paroxysmal tic (Tourette's syndrome)].
    Klinicheskaia meditsina, 1979, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Catecholamines; Child; Diagnosis, Differential; Electromyography; Female; Haloper

1979
[Rapid control of the acute patient by haloperidol administration].
    Acta psiquiatrica y psicologica de America latina, 1979, Volume: 25, Issue:3

    Topics: Acute Disease; England; Haloperidol; History, 20th Century; Humans; Hyperkinesis; Injections, Intram

1979
Clinical and experimental studies of phenytoin-induced hyperkinesias.
    Journal of neural transmission, 1979, Volume: 45, Issue:4

    Topics: Aged; Animals; Apomorphine; Basal Ganglia; Corpus Striatum; Dextroamphetamine; Disease Models, Anima

1979
Amphetamine-haloperidol interactions in rat striatum: failure to correlate behavioral effects with dopaminergic and cholinergic dynamics.
    Brain research, 1977, Apr-22, Volume: 126, Issue:1

    Topics: Amphetamine; Animals; Behavior, Animal; Catalepsy; Choline; Corpus Striatum; Dopamine; Drug Interact

1977
Neuroanatomical focus for morphine and enkephalin-induced hypermotility.
    Nature, 1977, Feb-17, Volume: 265, Issue:5595

    Topics: Animals; Apomorphine; Dopamine; Drug Interactions; Enkephalins; Haloperidol; Humans; Hyperkinesis; I

1977
Quipazine exacerbation of a hyperkinetic syndrome: involvement of brain dopamine and serotonin.
    Journal of neuroscience research, 1977, Volume: 3, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Dopamine; Female; Haloperidol; Humans; Hyperkinesis; Methysergide;

1977
The hyperkinetic syndrome following long-term haloperidol treatment: involvement of dopamine and noradrenaline.
    Journal of neural transmission, 1979, Volume: 44, Issue:3

    Topics: Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Dopamine; Dose-Response Relationship,

1979
Video editing and medication to produce a therapeutic self model.
    Journal of consulting and clinical psychology, 1977, Volume: 45, Issue:6

    Topics: Behavior Therapy; Child, Preschool; Haloperidol; Humans; Hyperkinesis; Intellectual Disability; Male

1977
The reliability and diagnostic validity of the physical and neurological examination for soft signs (PANESS).
    Journal of autism and childhood schizophrenia, 1976, Volume: 6, Issue:3

    Topics: Brain Damage, Chronic; Child; Child, Preschool; Evaluation Studies as Topic; Haloperidol; Humans; Hy

1976
Haloperidol.
    Journal of child psychology and psychiatry, and allied disciplines, 1975, Volume: 16, Issue:2

    Topics: Child; Child, Preschool; Haloperidol; Humans; Hyperkinesis; Intellectual Disability; Stuttering; Tic

1975
[Problems of diagnosis and treatment of deforming muscular dystrophy in children].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1990, Volume: 90, Issue:8

    Topics: Child; Diagnosis, Differential; Drug Therapy, Combination; Haloperidol; Hand Deformities, Acquired;

1990
[Use of haloperidol in the treatment of extrapyramidal compulsive movement].
    Der Nervenarzt, 1970, Volume: 41, Issue:11

    Topics: Adult; Aged; Chorea; Extrapyramidal Tracts; Female; Haloperidol; Humans; Huntington Disease; Hyperki

1970
[Differential diagnosis of acute extrapyramidal motor disorders in children. A case study].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1974, Volume: 26, Issue:8

    Topics: Acute Disease; Adolescent; Basal Ganglia Diseases; Diagnosis, Differential; Female; Haloperidol; Hep

1974
The role of brain dopamine in behavioral regulation and the actions of psychotropic drugs.
    The American journal of psychiatry, 1970, Volume: 127, Issue:2

    Topics: Amphetamine; Animals; Behavior; Brain; Brain Chemistry; Compulsive Behavior; Dopamine; Haloperidol;

1970
Gilles de la Tourette's syndrome following methylphenidate administration.
    Developmental medicine and child neurology, 1974, Volume: 16, Issue:1

    Topics: Age Factors; Child; Dopamine; Haloperidol; Humans; Hyperkinesis; Male; Methylphenidate; Neurologic M

1974
Tremor and involuntary movements in monkeys: effect of L-dopa and of a dopamine receptor stimulating agent.
    Science (New York, N.Y.), 1973, Feb-23, Volume: 179, Issue:4075

    Topics: 5-Hydroxytryptophan; Animals; Benzyl Compounds; Dihydroxyphenylalanine; Dioxoles; Drug Interactions;

1973
Drug treatment of tic and hyperkinesia in children.
    Activitas nervosa superior, 1973, Volume: 15, Issue:2

    Topics: Child; Child Behavior Disorders; Child, Preschool; Haloperidol; Humans; Hyperkinesis; Tic Disorders

1973
The management of excitement in a general hospital psychiatric ward by high dosage haloperidol.
    Acta psychiatrica Scandinavica, 1971, Volume: 47, Issue:4

    Topics: Administration, Oral; Adult; Aggression; Evaluation Studies as Topic; Female; Haloperidol; Hospitals

1971
[A chronic extrapyramidal syndrome as a complication of neuroleptic therapy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1969, Volume: 69, Issue:12

    Topics: Aged; Bipolar Disorder; Chlorpromazine; Chronic Disease; Extrapyramidal Tracts; Female; Haloperidol;

1969