haloperidol has been researched along with Hip Fractures in 7 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
Hip Fractures: Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES).
Excerpt | Relevance | Reference |
---|---|---|
"To study the effectiveness of haloperidol prophylaxis on incidence, severity, and duration of postoperative delirium in elderly hip-surgery patients at risk for delirium." | 9.11 | Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study. ( Bogaards, MJ; Burger, BJ; de Jonghe, JF; Egberts, TC; Eikelenboom, P; Kalisvaart, KJ; van Gool, WA; Vreeswijk, R, 2005) |
"Patients enrolled in a randomized controlled clinical trial of melatonin versus placebo on occurrence of delirium in hip-fracture patients." | 5.20 | In-Hospital Haloperidol Use and Perioperative Changes in QTc-Duration. ( Blom, MT; de Boer, A; de Jonghe, A; de Rooij, SE; Jansen, S; Tan, HL; van der Velde, N; van Munster, BC, 2015) |
"To study the effectiveness of haloperidol prophylaxis on incidence, severity, and duration of postoperative delirium in elderly hip-surgery patients at risk for delirium." | 5.11 | Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study. ( Bogaards, MJ; Burger, BJ; de Jonghe, JF; Egberts, TC; Eikelenboom, P; Kalisvaart, KJ; van Gool, WA; Vreeswijk, R, 2005) |
"Strategies to prevent and treat delirium during hospitalization for hip fracture have been less studied." | 1.40 | [Delirium prevention and treatment in elderly hip fracture]. ( Formiga, F; Robles, MJ; Vidán, MT, 2014) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (42.86) | 29.6817 |
2010's | 4 (57.14) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Robles, MJ | 1 |
Formiga, F | 1 |
Vidán, MT | 1 |
Blom, MT | 1 |
Jansen, S | 1 |
de Jonghe, A | 1 |
van Munster, BC | 1 |
de Boer, A | 1 |
de Rooij, SE | 1 |
Tan, HL | 1 |
van der Velde, N | 1 |
Freter, S | 1 |
Koller, K | 1 |
Dunbar, M | 1 |
MacKnight, C | 1 |
Rockwood, K | 1 |
Vochteloo, AJ | 1 |
Moerman, S | 1 |
van der Burg, BL | 1 |
de Boo, M | 1 |
de Vries, MR | 1 |
Niesten, DD | 1 |
Tuinebreijer, WE | 1 |
Nelissen, RG | 1 |
Pilot, P | 1 |
Kalisvaart, KJ | 2 |
de Jonghe, JF | 2 |
Bogaards, MJ | 1 |
Vreeswijk, R | 2 |
Egberts, TC | 1 |
Burger, BJ | 1 |
Eikelenboom, P | 2 |
van Gool, WA | 2 |
Dijkstra, M | 1 |
van Dis, H | 1 |
Kat, MG | 1 |
van der Ploeg, T | 1 |
Grover, M | 1 |
Edwards, F | 1 |
Hitchcock, K | 1 |
Stevens, MM | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Impact of Dexmedetomidine Combined With Ropivacaine for Postoperative Continuous Femoral Nerve Block on Postoperative Delirium and Long-term Oucomes in Elderly Patients After Single Knee Arthroplasty[NCT03629483] | Phase 4 | 736 participants (Anticipated) | Interventional | 2018-12-10 | Suspended (stopped due to Trial stopped by the sponsor because of no funding.) | ||
Usefulness of Bright Light Therapy in the Prevention of Delirium in Patients Undergoing Hematopoietic Stem Cell Transplant (HSCT)[NCT01700816] | 40 participants (Actual) | Interventional | 2012-10-31 | Terminated (stopped due to Low incidence of delirium.) | |||
Dynamic Light Application to Prevent ICU Acquired Delirium[NCT01274819] | 1,000 participants (Actual) | Interventional | 2011-07-31 | Completed | |||
Impact of Dexmedetomidine Supplemented Intravenous Analgesia on Postoperative Delirium and Long-term Outcomes in Elderly After Orthopedic Surgery: A Multicenter, Double-blinded, Randomized Controlled Trial[NCT03629262] | Phase 4 | 712 participants (Actual) | Interventional | 2018-10-28 | Active, not recruiting | ||
Impact of Dexmedetomidine Supplemented Analgesia on Delirium and Long-term Outcomes in Elderly After Hip Fracture Surgery: A Multicenter, Double-blinded, Randomized Controlled Trial[NCT04955249] | Phase 4 | 1,440 participants (Anticipated) | Interventional | 2021-11-18 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
Intervention | volume percentage (vol%) of red blood ce (Median) |
---|---|
Bright Light Therapy | 28.20 |
Sham Light | 26.70 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
Intervention | g/dl (Median) |
---|---|
Bright Light Therapy | 9.70 |
Sham Light | 9.55 |
(NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
Intervention | days (Median) |
---|---|
Bright Light Therapy | 18 |
Sham Light | 18.5 |
Monday, Wednesday, and Friday assessments will begin after beginning light therapy and include the Delirium Rating Scale-Revised-98 (DRS-98)and Memorial Delirium Assessment Scale (MDAS) (NCT01700816)
Timeframe: From hospital admission until the date of first documented delirium, assessed up to 28 days post-transplant
Intervention | Participants (Count of Participants) |
---|---|
Bright Light Therapy | 1 |
Sham Light | 0 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
Intervention | thousand cells/uL (Median) |
---|---|
Bright Light Therapy | 39 |
Sham Light | 33.5 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
Intervention | M/uL (Median) |
---|---|
Bright Light Therapy | 3.21 |
Sham Light | 2.93 |
"Monday, Wednesday, and Friday assessments of the Memorial Delirium Assessment Scale (MDAS); Patients will receive assessments after beginning light therapy until day 28 post-transplant or discharge, whichever comes first.~10 item scale Items are rated on a four-point scale from 0 (none) to 3 (severe) depending on the level of impairment, rendering a maximum possible score of 30.~A score of 13 has been recommended as a cut-off for establishing the diagnosis of delirium" (NCT01700816)
Timeframe: From first documented episode of delirium until discharge from the hospital, assessed up to 28 days post-transplant
Intervention | units on a scale (Number) |
---|---|
Bright Light Therapy | 18 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
Intervention | K/uL (Median) |
---|---|
Bright Light Therapy | 2.30 |
Sham Light | 4.75 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT. (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
Intervention | mg/dl (Median) | |
---|---|---|
Serum Creatinine | Blood Urea Nitrogen (BUN) | |
Bright Light Therapy | 0.66 | 9 |
Sham Light | 0.75 | 8.5 |
Lab values at latest available follow-up date per participant. These tests are performed as part of routine clinical care on patients undergoing HSCT (Hematopoietic Stem Cell Transplantation). (NCT01700816)
Timeframe: From admission to hospital to discharge, an expected average of 28 days post-transplant
Intervention | mmol/L (Median) | |||
---|---|---|---|---|
Sodium (Na) | Potassium (K) | Chloride (Cl) | Carbon Dioxide (CO2) | |
Bright Light Therapy | 139 | 3.6 | 105 | 24.9 |
Sham Light | 138.0 | 3.80 | 103.0 | 25.10 |
4 trials available for haloperidol and Hip Fractures
Article | Year |
---|---|
In-Hospital Haloperidol Use and Perioperative Changes in QTc-Duration.
Topics: Aged, 80 and over; Antipsychotic Agents; Cohort Studies; Delirium; Electrocardiography; Female; Halo | 2015 |
Translating Delirium Prevention Strategies for Elderly Adults with Hip Fracture into Routine Clinical Care: A Pragmatic Clinical Trial.
Topics: Aged; Aged, 80 and over; Analgesics; Anti-Dyskinesia Agents; Dehydration; Delirium; Female; Haloperi | 2017 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Delirium; Double-Blind Method; Female; Haloperidol; H | 2005 |
Early symptoms in the prodromal phase of delirium: a prospective cohort study in elderly patients undergoing hip surgery.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; APACHE; Cohort Studies; Delirium; Double-Blind Method | 2007 |
3 other studies available for haloperidol and Hip Fractures
Article | Year |
---|---|
[Delirium prevention and treatment in elderly hip fracture].
Topics: Aged; Anesthesia, Epidural; Anesthesia, General; Benzodiazepines; Cognition Disorders; Combined Moda | 2014 |
Delirium risk screening and haloperidol prophylaxis program in hip fracture patients is a helpful tool in identifying high-risk patients, but does not reduce the incidence of delirium.
Topics: Aged; Aged, 80 and over; Cohort Studies; Delirium; Female; Haloperidol; Hip Fractures; Humans; Incid | 2011 |
Clinical inquiries. What steps can reduce morbidity and mortality caused by hip fractures?
Topics: Aged; Analgesics; Antibiotic Prophylaxis; Antipsychotic Agents; Bacterial Infections; Cephalosporins | 2007 |