haloperidol has been researched along with Glioma in 16 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study examines the effects of antipsychotic drugs, haloperidol and risperidone, on the expression of HSP70 produced by MK-801 in rat C6 glioma cells." | 7.74 | Effects of haloperidol and risperidone on the expression of heat shock protein 70 in MK-801-treated rat C6 glioma cells. ( Chai, YG; Choi, J; Choi, MR; Kim, D; Kim, DJ; Kim, SH; Lee, JS; Park, YC; Roh, K; Roh, S; Yang, BH, 2008) |
| "We have investigated the expression of neuropeptide Y (NPY) in C6 glioma cells after the glutamatergic stimulation by the in situ RT-PCR and immunocytochemical techniques." | 7.70 | Expression of neuropeptide Y by glutamatergic stimulation in rat C6 glioma cells. ( Choe, BK; Kim, SK; Kwon, GY; Shin, SW, 2000) |
| "In this study, the inhibitory effects of R(-)-NPA (R(-)-Propylnorapomorphine) and haloperidol on voltage-dependent K+ currents in rat C6 glioma cells (C6 cells) were observed by means of the whole-cell patch-clamp recording technique." | 7.69 | [Inhibition of voltage-dependent K+ currents in rat C6 glioma cells by haloperidol and R(-)-NPA]. ( He, SF; Xie, Z, 1997) |
| " We used two-dimensional gel electrophoresis coupled with MALDI-TOF/TOF mass spectrometry protein identification to analyze differentially expressed proteins in haloperidol-, risperidone-, and clozapine-treated C6 glioma cells." | 3.79 | Two-dimensional gel electrophoresis revealed antipsychotic drugs induced protein expression modulations in C6 glioma cells. ( Chen, ML, 2013) |
| " We illustrate our approach by analyzing the effects induced by two sigma-1 receptor ligands (haloperidol and 4-IBP) on the behavior of two glioma cell lines using two in vitro cell models, i." | 3.74 | Videomicroscopic extraction of specific information on cell proliferation and migration in vitro. ( Debeir, O; Decaestecker, C; Kiss, R; Mégalizzi, V; Warzée, N, 2008) |
| " The present study examines the effects of antipsychotic drugs, haloperidol and risperidone, on the expression of HSP70 produced by MK-801 in rat C6 glioma cells." | 3.74 | Effects of haloperidol and risperidone on the expression of heat shock protein 70 in MK-801-treated rat C6 glioma cells. ( Chai, YG; Choi, J; Choi, MR; Kim, D; Kim, DJ; Kim, SH; Lee, JS; Park, YC; Roh, K; Roh, S; Yang, BH, 2008) |
| " Using a microarray approach, we here demonstrate that the antipsychotic drugs clozapine and haloperidol upregulate several genes involved in cholesterol and fatty acid biosynthesis in cultured human glioma cells, including HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase), HMGCS1 (3-hydroxy-3-methylglutaryl-coenzyme A synthase-1), FASN (fatty acid synthase) and SCD (stearoyl-CoA desaturase)." | 3.73 | Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action? ( Berge, RK; Breilid, H; Fernø, J; Glambek, M; Løvlie, R; Raeder, MB; Skrede, S; Stansberg, C; Steen, VM; Tronstad, KJ; Vik-Mo, AO, 2005) |
| "We investigated the effects of the atypical antipsychotic drugs quetiapine and clozapine and the typical antipsychotic haloperidol on the secretion of GDNF from rat C6 glioma cells." | 3.73 | Antipsychotic drugs cause glial cell line-derived neurotrophic factor secretion from C6 glioma cells. ( Dyck, LE; Li, XM; Shao, Z; Wang, H, 2006) |
| "We have investigated the expression of neuropeptide Y (NPY) in C6 glioma cells after the glutamatergic stimulation by the in situ RT-PCR and immunocytochemical techniques." | 3.70 | Expression of neuropeptide Y by glutamatergic stimulation in rat C6 glioma cells. ( Choe, BK; Kim, SK; Kwon, GY; Shin, SW, 2000) |
| "Haloperidol, a dopamine receptor antagonist and sigma-receptor-active neuroleptic drug, is cytotoxic to primary hippocampal neurones, C6 glioma cells and NCB20 cells." | 3.69 | Haloperidol-induced cell death--mechanism and protection with vitamin E in vitro. ( Behl, C; Holsboer, F; Rupprecht, R; Skutella, T, 1995) |
| "In this study, the inhibitory effects of R(-)-NPA (R(-)-Propylnorapomorphine) and haloperidol on voltage-dependent K+ currents in rat C6 glioma cells (C6 cells) were observed by means of the whole-cell patch-clamp recording technique." | 3.69 | [Inhibition of voltage-dependent K+ currents in rat C6 glioma cells by haloperidol and R(-)-NPA]. ( He, SF; Xie, Z, 1997) |
| "Pretreatment of haloperidol significantly reduced the radiotracer accumulation of [(99m)Tc]23 or [(99m)Tc]24 in the brain." | 1.40 | Novel cyclopentadienyl tricarbonyl (99m)tc complexes containing 1-piperonylpiperazine moiety: potential imaging probes for sigma-1 receptors. ( Brust, P; Cui, M; Deuther-Conrad, W; Jia, B; Jia, H; Li, D; Liu, B; Lu, J; Steinbach, J; Wang, X; Xie, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sozio, P | 1 |
| Fiorito, J | 2 |
| Di Giacomo, V | 2 |
| Di Stefano, A | 2 |
| Marinelli, L | 2 |
| Cacciatore, I | 2 |
| Cataldi, A | 2 |
| Pacella, S | 2 |
| Turkez, H | 1 |
| Parenti, C | 1 |
| Rescifina, A | 1 |
| Marrazzo, A | 2 |
| Wang, X | 1 |
| Li, D | 1 |
| Deuther-Conrad, W | 1 |
| Lu, J | 1 |
| Xie, Y | 1 |
| Jia, B | 1 |
| Cui, M | 1 |
| Steinbach, J | 1 |
| Brust, P | 1 |
| Liu, B | 1 |
| Jia, H | 1 |
| Patruno, A | 1 |
| Rapino, M | 1 |
| Fornasari, E | 1 |
| Prezzavento, O | 1 |
| Debeir, O | 1 |
| Mégalizzi, V | 1 |
| Warzée, N | 1 |
| Kiss, R | 1 |
| Decaestecker, C | 1 |
| Roh, K | 1 |
| Roh, S | 1 |
| Yang, BH | 1 |
| Lee, JS | 1 |
| Chai, YG | 1 |
| Choi, MR | 1 |
| Park, YC | 1 |
| Kim, DJ | 1 |
| Kim, D | 1 |
| Choi, J | 1 |
| Kim, SH | 1 |
| Chen, ML | 1 |
| de Souza, DF | 1 |
| Wartchow, K | 1 |
| Hansen, F | 1 |
| Lunardi, P | 1 |
| Guerra, MC | 1 |
| Nardin, P | 1 |
| Gonçalves, CA | 1 |
| Fernø, J | 1 |
| Raeder, MB | 1 |
| Vik-Mo, AO | 1 |
| Skrede, S | 1 |
| Glambek, M | 1 |
| Tronstad, KJ | 1 |
| Breilid, H | 1 |
| Løvlie, R | 1 |
| Berge, RK | 1 |
| Stansberg, C | 1 |
| Steen, VM | 1 |
| Shao, Z | 1 |
| Dyck, LE | 1 |
| Wang, H | 1 |
| Li, XM | 1 |
| Behl, C | 1 |
| Rupprecht, R | 1 |
| Skutella, T | 1 |
| Holsboer, F | 1 |
| Kagaya, A | 1 |
| Motohashi, N | 1 |
| Kugaya, A | 1 |
| Yamaji, T | 1 |
| Hayashi, T | 1 |
| Okamoto, Y | 1 |
| Shinno, H | 1 |
| Takebayashi, M | 1 |
| Uchitomi, Y | 1 |
| Yamawaki, S | 1 |
| Griffon, N | 1 |
| Pilon, C | 1 |
| Sautel, F | 1 |
| Schwartz, JC | 1 |
| Sokoloff, P | 1 |
| Xie, Z | 1 |
| He, SF | 1 |
| Kim, SK | 1 |
| Kwon, GY | 1 |
| Shin, SW | 1 |
| Choe, BK | 1 |
| Friedman, SJ | 1 |
| Skehan, P | 1 |
| Traber, J | 1 |
| Reiser, G | 1 |
| Fischer, K | 1 |
| Hamprecht, B | 1 |
16 other studies available for haloperidol and Glioma
| Article | Year |
|---|---|
Haloperidol metabolite II prodrug: asymmetric synthesis and biological evaluation on rat C6 glioma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Survival; Dose-Response Relationship, Drug; Drug Scr | 2015 |
Novel cyclopentadienyl tricarbonyl (99m)tc complexes containing 1-piperonylpiperazine moiety: potential imaging probes for sigma-1 receptors.
Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Glioma; Haloperidol; Ligands; Male; Mice, Inbred | 2014 |
Effect of MRJF4 on C6 Glioma Cells Proliferation and Migration.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Glioma; Haloperidol; NF-kappa B; Pheny | 2017 |
Videomicroscopic extraction of specific information on cell proliferation and migration in vitro.
Topics: Animals; Benzamides; Cell Division; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Screen | 2008 |
Effects of haloperidol and risperidone on the expression of heat shock protein 70 in MK-801-treated rat C6 glioma cells.
Topics: Animals; Cell Line, Tumor; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagoni | 2008 |
Two-dimensional gel electrophoresis revealed antipsychotic drugs induced protein expression modulations in C6 glioma cells.
Topics: Animals; Antipsychotic Agents; Cell Line, Tumor; Clozapine; Electrophoresis, Gel, Two-Dimensional; F | 2013 |
Interleukin-6-induced S100B secretion is inhibited by haloperidol and risperidone.
Topics: Animals; Antipsychotic Agents; Cell Line, Tumor; Cytokines; Enzyme-Linked Immunosorbent Assay; Glial | 2013 |
Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?
Topics: Antipsychotic Agents; Cell Line, Tumor; Cholesterol; Clozapine; Fatty Acid Synthases; Fatty Acids; G | 2005 |
Antipsychotic drugs cause glial cell line-derived neurotrophic factor secretion from C6 glioma cells.
Topics: Animals; Antipsychotic Agents; Cell Line, Tumor; Clozapine; Dibenzothiazepines; Enzyme-Linked Immuno | 2006 |
Haloperidol-induced cell death--mechanism and protection with vitamin E in vitro.
Topics: Animals; Antipsychotic Agents; Apoptosis; Cell Death; Cricetinae; Cricetulus; Dopamine Antagonists; | 1995 |
Cyclic GMP generation mediated by 5-HT-2 receptors via nitric oxide-dependent pathway and its effect on the desensitization of 5-HT-2 receptors in C6 glioma cells.
Topics: Animals; Arginine; Calcium; Chelating Agents; Cyclic GMP; Dopamine Antagonists; Edetic Acid; Egtazic | 1995 |
Antipsychotics with inverse agonist activity at the dopamine D3 receptor.
Topics: Animals; Antipsychotic Agents; Calcium; CHO Cells; Clozapine; Colforsin; Cricetinae; Cyclic AMP; DNA | 1996 |
[Inhibition of voltage-dependent K+ currents in rat C6 glioma cells by haloperidol and R(-)-NPA].
Topics: Animals; Apomorphine; Biological Transport, Active; Brain Neoplasms; Dopamine Agonists; Dopamine Ant | 1997 |
Expression of neuropeptide Y by glutamatergic stimulation in rat C6 glioma cells.
Topics: Animals; Dopamine; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Haloperidol; Kaini | 2000 |
The inhibition of sterol synthesis by anesthetics.
Topics: Acetates; Anesthetics, Local; Animals; Cell Line; Chlorpromazine; Diphenylacetic Acids; Glioma; Halo | 1979 |
Measurements of adenosine 3':5'-cyclic monophosphate and membrane potential in neuroblastoma times glioma hybrid cells: opiates and adrenergic agonists cause effects opposite to those of prostaglandin E1.
Topics: Animals; Cell Line; Clone Cells; Cyclic AMP; Dopamine; Glioma; Haloperidol; Hybrid Cells; Isoprotere | 1975 |