haloperidol has been researched along with Glaucoma in 9 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a double-blind randomised, prospective single dose study, we measured intraocular pressure (IOP), pupil diameter, systemic blood pressure and heart rate in 43 ocular normotensive subjects before (baseline) and 2, 4, and 6 hours after topical instillation of the following drugs: dopamine 2% (n = 11), a dopamine receptor blocking drug, haloperidol 0." | 9.07 | The effects of dopamine, haloperidol and bromocriptine on intraocular pressure. ( Elibol, O; Güler, C; Yüksel, N, 1992) |
| "Haloperidol, a dopaminergic antagonist, was found to be very effective in lowering intraocular pressure in normal and glaucomatous eyes." | 7.69 | Evaluation of haloperidol, a dopamine antagonist, on intraocular pressure in experimental glaucoma. ( Gupta, MC; Khosla, P; Kothari, S; Srivastava, RK, 1996) |
| "Although it is essential that intraocular pressure (IOP) be reduced in glaucoma treatment, it is also vitally important to provide sufficient blood flow to eye tissues so that healthy visual field is maintained." | 7.67 | Effects of antiglaucoma drugs on the blood flow in rabbit eyes. ( Chiou, GC; Yan, HY, 1986) |
| "In a double-blind randomised, prospective single dose study, we measured intraocular pressure (IOP), pupil diameter, systemic blood pressure and heart rate in 43 ocular normotensive subjects before (baseline) and 2, 4, and 6 hours after topical instillation of the following drugs: dopamine 2% (n = 11), a dopamine receptor blocking drug, haloperidol 0." | 5.07 | The effects of dopamine, haloperidol and bromocriptine on intraocular pressure. ( Elibol, O; Güler, C; Yüksel, N, 1992) |
| "Although it is essential that intraocular pressure (IOP) be reduced in glaucoma treatment, it is also vitally important to provide sufficient blood flow to eye tissues so that healthy visual field is maintained." | 3.67 | Effects of antiglaucoma drugs on the blood flow in rabbit eyes. ( Chiou, GC; Yan, HY, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bandych-Biniszkiewiczowa, D | 1 |
| Chiou, GC | 2 |
| Khosla, P | 2 |
| Kothari, S | 2 |
| Gupta, MC | 2 |
| Srivastava, RK | 1 |
| Elibol, O | 1 |
| Güler, C | 1 |
| Yüksel, N | 1 |
| Sheppard, JD | 1 |
| Schaid, DJ | 2 |
| Sheppard, J | 1 |
| Lavin, MJ | 1 |
| Andrews, V | 1 |
| Yan, HY | 1 |
4 trials available for haloperidol and Glaucoma
| Article | Year |
|---|---|
The effects of dopamine, haloperidol and bromocriptine on intraocular pressure.
Topics: Adult; Bromocriptine; Dopamine; Double-Blind Method; Glaucoma; Haloperidol; Humans; Intraocular Pres | 1992 |
Oral haloperidol lowers human intraocular pressure.
Topics: Administration, Oral; Adult; Aged; Female; Glaucoma; Haloperidol; Humans; Intraocular Pressure; Male | 1986 |
Ocular hypotensive effect of haloperidol.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma; Haloperidol; Humans; I | 1986 |
Is topical haloperidol a useful glaucoma treatment?
Topics: Administration, Topical; Double-Blind Method; Glaucoma; Haloperidol; Humans; Intraocular Pressure; K | 1986 |
5 other studies available for haloperidol and Glaucoma
| Article | Year |
|---|---|
[Action of several neuroleptics and diazepam on the hydrodynamics of the eye in healthy people and glaucoma patients].
Topics: Adult; Antipsychotic Agents; Chlorprothixene; Diazepam; Droperidol; Fluspirilene; Glaucoma; Haloperi | 1983 |
Treatment of ocular hypertension and glaucoma with dopamine antagonists.
Topics: Animals; Antipsychotic Agents; Butyrophenones; Dopamine Antagonists; Female; Glaucoma; Guinea Pigs; | 1984 |
Evaluation of haloperidol, a dopamine antagonist, on intraocular pressure in experimental glaucoma.
Topics: Animals; Dopamine Antagonists; Evaluation Studies as Topic; Female; Glaucoma; Haloperidol; Intraocul | 1996 |
Effect of haloperidol, a dopamine antagonist on aqueous humour dynamics in experimental glaucoma.
Topics: Animals; Aqueous Humor; Dopamine Antagonists; Female; Glaucoma; Haloperidol; Intraocular Pressure; M | 1996 |
Effects of antiglaucoma drugs on the blood flow in rabbit eyes.
Topics: Animals; Blood Flow Velocity; Butyrophenones; Drug Evaluation, Preclinical; Eye; Glaucoma; Haloperid | 1986 |