haloperidol has been researched along with Fatty Liver in 3 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
Fatty Liver: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to investigate the difference between the pharmacokinetics of haloperidol in normal rats and in rats with fatty liver disease." | 7.78 | The blood concentration and organ distribution of haloperidol at therapeutic and toxic doses in severe fatty liver disease. ( Ikemura, M; Inoue, H; Nakagawa, Y; Nata, M; Shinone, K, 2012) |
| " The aim of this study is to investigate the adverse effects of antipsychotic drugs on fatty liver." | 5.35 | Gene expression on liver toxicity induced by administration of haloperidol in rats with severe fatty liver. ( Hanagama, M; Inoue, H; Kamiya, M; Nata, M; Shinone, K, 2008) |
| "The aim of this study was to investigate the difference between the pharmacokinetics of haloperidol in normal rats and in rats with fatty liver disease." | 3.78 | The blood concentration and organ distribution of haloperidol at therapeutic and toxic doses in severe fatty liver disease. ( Ikemura, M; Inoue, H; Nakagawa, Y; Nata, M; Shinone, K, 2012) |
| " The aim of this study is to investigate the adverse effects of antipsychotic drugs on fatty liver." | 1.35 | Gene expression on liver toxicity induced by administration of haloperidol in rats with severe fatty liver. ( Hanagama, M; Inoue, H; Kamiya, M; Nata, M; Shinone, K, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ikemura, M | 1 |
| Nakagawa, Y | 1 |
| Shinone, K | 2 |
| Inoue, H | 2 |
| Nata, M | 2 |
| Hanagama, M | 1 |
| Kamiya, M | 1 |
| Woytoń, J | 1 |
| Szacki, J | 1 |
| Dzioba, A | 1 |
| Rabczyński, J | 1 |
| Woytoń, A | 1 |
3 other studies available for haloperidol and Fatty Liver
| Article | Year |
|---|---|
The blood concentration and organ distribution of haloperidol at therapeutic and toxic doses in severe fatty liver disease.
Topics: Animals; Antipsychotic Agents; Area Under Curve; Fatty Liver; Haloperidol; Male; Portal Vein; Rats; | 2012 |
Gene expression on liver toxicity induced by administration of haloperidol in rats with severe fatty liver.
Topics: Alanine Transaminase; Animals; Antipsychotic Agents; Apoptosis; Aryl Hydrocarbon Hydroxylases; Aspar | 2008 |
Influence of industrial toxic compounds on pregnancy. I. Pregnant guinea pigs exposed to the epoxide resin Epidian 5.
Topics: Administration, Topical; Animals; Epoxy Resins; Fatty Liver; Female; Fetal Death; Guinea Pigs; Hyper | 1975 |