haloperidol has been researched along with Experimental Leukemia in 5 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the 18-month study, haloperidol was injected intraperitoneally as a solution (HaldolR) at a dosage of 5 mg/kg daily for 5, 10 and 20 consecutive days in 5-week-old mice." | 1.27 | Mutagenic and leukemogenic activity of haloperidol: a negative study. ( de Meester, C; Lambotte-Vandepaer, M; Marsboom, R; Van Cauteren, H; Vandenberghe, J; Vanparys, P, 1987) |
| "Haloperidol was also shown to be mutagenic in the Ames Salmonella test system." | 1.26 | Leukaemogenic and mutagenic activity of the butyrophenon, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone (haloperidol). ( Fey, F; Köhler, S; Sydow, G; Teichmann, B; Wunderlich, V, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fey, F | 4 |
| Wunderlich, V | 4 |
| Sydow, G | 4 |
| Teichmann, B | 1 |
| Köhler, S | 1 |
| Van Cauteren, H | 1 |
| Vanparys, P | 1 |
| de Meester, C | 1 |
| Lambotte-Vandepaer, M | 1 |
| Vandenberghe, J | 1 |
| Marsboom, R | 1 |
5 other studies available for haloperidol and Experimental Leukemia
| Article | Year |
|---|---|
[Induction of monocytic-myelocytic mixed cell leukemias after the application of the neuroleptic haloperidol in mice].
Topics: Animals; Haloperidol; Injections, Intraperitoneal; Leukemia, Experimental; Leukemia, Myeloid; Lymph | 1984 |
Leukaemogenic and mutagenic activity of the butyrophenon, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone (haloperidol).
Topics: Animals; Haloperidol; Injections, Intraperitoneal; Leukemia, Experimental; Male; Mice; Mice, Inbred | 1982 |
Antiviral effect of haloperidol on Rauscher murine leukemia virus.
Topics: Animals; Haloperidol; Leukemia, Experimental; Male; Mice; Mice, Inbred Strains; Rauscher Virus | 1980 |
Mutagenic and leukemogenic activity of haloperidol: a negative study.
Topics: Animals; Haloperidol; Injections, Intraperitoneal; Leukemia, Experimental; Male; Mice; Mice, Inbred | 1987 |
Further characterization of the leukemogenic activity of haloperidol in mice.
Topics: Animals; Drug Interactions; Female; Haloperidol; Leukemia, Experimental; Male; Methylnitrosourea; Mi | 1987 |