haloperidol has been researched along with Encephalopathy, Toxic in 15 studies
Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study investigates the molecular etiology of haloperidol neurotoxicity and the role of curcumin, a well-known anti-oxidant, in ameliorating these adverse effects." | 1.37 | Protective effect of curcumin and its combination with piperine (bioavailability enhancer) against haloperidol-associated neurotoxicity: cellular and neurochemical evidence. ( Bishnoi, M; Chopra, K; Kulkarni, SK; Rongzhu, L, 2011) |
| "Haloperidol and clozapine treatment significantly decreased the nigral expression of bax (p<0." | 1.34 | Differential nigral expression of Bcl-2 protein family in chronically haloperidol and clozapine-treated rats: role in neurotoxicity and stereotyped behavior. ( Aguilar, E; Bonastre, M; Marin, C; Saldaña, M, 2007) |
| "Haloperidol has been shown to induce the expression of the transcription factor nuclear factor-kappaB (NFkappaB)." | 1.33 | Role of nigral NFkappaB p50 and p65 subunit expression in haloperidol-induced neurotoxicity and stereotyped behavior in rats. ( Aguilar, E; Bonastre, M; Marin, C; Saldaña, M, 2006) |
| " Adverse effects from the use of haloperidol such as prolonged QTc, dystonic reactions, and torsades de pointes were recorded." | 1.33 | Pharmacologic treatment of acute pediatric methamphetamine toxicity. ( Ruha, AM; Yarema, MC, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Kadir, A | 1 |
| Singh, J | 1 |
| Rahi, V | 4 |
| Kumar, P | 4 |
| Ram, P | 3 |
| Li, K | 1 |
| Horng, H | 1 |
| Lynch, K | 1 |
| Smollin, CG | 1 |
| Espinosa-Oliva, AM | 1 |
| de Pablos, RM | 1 |
| Santiago, M | 1 |
| Moshiri, M | 1 |
| Mohammadpour, AH | 1 |
| Vahabzadeh, M | 1 |
| Etemad, L | 1 |
| Memar, B | 1 |
| Hosseinzadeh, H | 1 |
| Zheng, M | 1 |
| Zhang, H | 1 |
| Dill, DL | 1 |
| Clark, JD | 1 |
| Tu, S | 1 |
| Yablonovitch, AL | 1 |
| Tan, MH | 1 |
| Zhang, R | 1 |
| Rujescu, D | 1 |
| Wu, M | 1 |
| Tessarollo, L | 1 |
| Vieira, W | 1 |
| Gottesman, MM | 1 |
| Deng, S | 1 |
| Eberlin, LS | 1 |
| Zare, RN | 1 |
| Billard, JM | 1 |
| Gillet, JP | 1 |
| Li, JB | 1 |
| Peltz, G | 1 |
| Górska, A | 1 |
| Marszałł, M | 1 |
| Sloderbach, A | 1 |
| Bishnoi, M | 1 |
| Chopra, K | 1 |
| Rongzhu, L | 1 |
| Kulkarni, SK | 1 |
| Collins, LE | 1 |
| Sager, TN | 1 |
| Sams, AG | 1 |
| Pennarola, A | 1 |
| Port, RG | 1 |
| Shahriari, M | 1 |
| Salamone, JD | 1 |
| Park, CH | 1 |
| Park, TW | 1 |
| Yang, JC | 1 |
| Lee, KH | 1 |
| Huang, GB | 1 |
| Tong, Z | 1 |
| Park, MS | 1 |
| Chung, YC | 1 |
| Nakahara, T | 1 |
| Kuroki, T | 1 |
| Ohta, E | 1 |
| Kajihata, T | 1 |
| Yamada, H | 1 |
| Yamanaka, M | 1 |
| Hashimoto, K | 1 |
| Tsutsumi, T | 1 |
| Hirano, M | 1 |
| Uchimura, H | 1 |
| Saldaña, M | 2 |
| Bonastre, M | 2 |
| Aguilar, E | 2 |
| Marin, C | 2 |
| Ruha, AM | 1 |
| Yarema, MC | 1 |
| Casey, DE | 1 |
2 reviews available for haloperidol and Encephalopathy, Toxic
| Article | Year |
|---|---|
[The neurotoxicity of pyridinium metabolites of haloperidol].
Topics: Antipsychotic Agents; Biotransformation; Brain; Delirium; Haloperidol; Humans; Nausea; Neurodegenera | 2015 |
Tardive dyskinesia: pathophysiology and animal models.
Topics: Age Factors; Animals; Antipsychotic Agents; Basal Ganglia; Behavior, Animal; Disease Models, Animal; | 2000 |
1 trial available for haloperidol and Encephalopathy, Toxic
| Article | Year |
|---|---|
No negative symptoms in healthy volunteers after single doses of amisulpride, aripiprazole, and haloperidol: a double-blind placebo-controlled trial.
Topics: Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Cognitive Dysfunction; Dizziness; Double-Bli | 2012 |
12 other studies available for haloperidol and Encephalopathy, Toxic
| Article | Year |
|---|---|
Berberine Ameliorate Haloperidol and 3-Nitropropionic Acid-Induced Neurotoxicity in Rats.
Topics: Animals; Antioxidants; Berberine; Catalase; Haloperidol; Huntington Disease; Motor Activity; Neuropr | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Topics: Animals; Filgrastim; Granulocyte Colony-Stimulating Factor; Haloperidol; Huntington Disease; Movemen | 2022 |
Prolonged toxicity from Kambo cleansing ritual.
Topics: Adult; Animals; Anti-Allergic Agents; Anti-Anxiety Agents; Antipsychotic Agents; Anura; Ceremonial B | 2018 |
In vivo effect of apomorphine and haloperidol on MPP neurotoxicity.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apomorphine; Corpus Striatum; Dopamine; Dopamine Agonists; Dop | 2014 |
Evaluating the effects and safety of intravenous lipid emulsion on haloperidol-induced neurotoxicity in rabbit.
Topics: Animals; Body Temperature; Catalepsy; Fat Emulsions, Intravenous; Haloperidol; In Situ Nick-End Labe | 2014 |
The role of Abcb5 alleles in susceptibility to haloperidol-induced toxicity in mice and humans.
Topics: Adolescent; Adult; Alleles; Animals; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfami | 2015 |
Protective effect of curcumin and its combination with piperine (bioavailability enhancer) against haloperidol-associated neurotoxicity: cellular and neurochemical evidence.
Topics: Alkaloids; Analysis of Variance; Animals; Apoptosis; Behavior, Animal; Benzodioxoles; Caspase 3; Col | 2011 |
The novel adenosine A2A antagonist Lu AA47070 reverses the motor and motivational effects produced by dopamine D2 receptor blockade.
Topics: Adenosine A2 Receptor Antagonists; Animals; Behavior, Animal; Choice Behavior; Depression; Dopamine | 2012 |
Effect of the neurotoxic dose of methamphetamine on gene expression of parkin and Pael-receptors in rat striatum.
Topics: Animals; Antipsychotic Agents; Central Nervous System Stimulants; Gene Expression; Genes, fos; Halop | 2003 |
Role of nigral NFkappaB p50 and p65 subunit expression in haloperidol-induced neurotoxicity and stereotyped behavior in rats.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Blotting, Western; Clozapine; Dopamine Plasma Membr | 2006 |
Differential nigral expression of Bcl-2 protein family in chronically haloperidol and clozapine-treated rats: role in neurotoxicity and stereotyped behavior.
Topics: Animals; Antipsychotic Agents; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Clozapi | 2007 |
Pharmacologic treatment of acute pediatric methamphetamine toxicity.
Topics: Benzodiazepines; Central Nervous System Depressants; Central Nervous System Stimulants; Child; Child | 2006 |