Page last updated: 2024-10-28

haloperidol and Dystonia

haloperidol has been researched along with Dystonia in 112 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)

Research Excerpts

ExcerptRelevanceReference
"Randomised controlled trials (RCTs) involving people exhibiting aggression and/or agitation thought to be due to psychosis, allocated rapid use of haloperidol alone (by any route), compared with any other treatment."8.95Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation). ( Adams, CE; Brooke-Powney, MJ; Li, X; Ostinelli, EG, 2017)
"To evaluate the clinical effects of haloperidol for the management of schizophrenia and other similar serious mental illnesses compared with placebo."8.89Haloperidol versus placebo for schizophrenia. ( Adams, CE; Bergman, H; Irving, CB; Lawrie, S, 2013)
"Randomised controlled  trials (RCTs) involving people exhibiting agitation or aggression (or both) thought to be due to psychosis, allocated rapid use of haloperidol alone (by any route), compared with any other treatment."8.88Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation). ( Adams, CE; Jones, H; Powney, MJ, 2012)
"A 28-year-old woman presenting with agitation and mania with psychotic features developed symptoms of isolated lingual dystonia shortly after the initiation of a haloperidol concentrate regimen."8.02Haloperidol-induced isolated lingual dystonia. ( Chapa, A; Helminiak, A; Jin, JW; Kockara, N, 2021)
" He had relapse symptoms of schizophrenia and had recently received a single dose of parenteral haloperidol to manage his agitation."7.85Persistent oromandibular dystonia and angioedema secondary to haloperidol. ( Masiran, R, 2017)
"We discus the case of a forty-nine year old patient with haloperidol induced laryngeal dystonia (LD)."7.74A patient with haloperidol induced laryngeal dystonia. ( Peek, DF, 2008)
"To report a case of delayed-onset dystonic reactions, oculogyric crisis (OGC), and torticollis after treatment with intramuscular haloperidol lactate injection."7.72Delayed onset of oculogyric crisis and torticollis with intramuscular haloperidol. ( Jhee, SS; Mohaupt, SM; Sims, SJ; Yones, CL; Zarotsky, V, 2003)
" Therefore, we have studied the effect of different 5-HT drugs and one anticholinergic drug in acute dystonia in five cebus monkeys chronically treated with haloperidol."7.67Effects of serotonergic and anticholinergic drugs in haloperidol-induced dystonia in Cebus monkeys. ( Gerlach, J; Korsgaard, S; Laursen, AL; Noring, U; Povlsen, UJ, 1986)
"The use of baclofen, a structural analog of gamma-aminobutyric acid (GABA), is described in the treatment of a patient with tardive dystonia."7.67Baclofen treatment in a patient with tardive dystonia. ( Allen, A; Lux, WE; Rosse, RB, 1986)
"Then at the age of eight, she developed dystonia of the left lower extremity that became noticeable toward evening but subsided after taking sleep."5.28[Response to haloperidol and analysis of growth curve in hereditary progressive dystonia with marked diurnal fluctuation]. ( Cho, K; Kusunoki, Y; Oki, J; Sasaki, N, 1989)
"Sixty-two first-episode psychotic patients who were neuroleptic-naive were studied to examine predictors of acute dystonia after treatment with haloperidol."5.07Predictors of acute dystonia in first-episode psychotic patients. ( Aguilar, EJ; Gómez-Beneyto, M; Hernández, J; Keshavan, MS; Martínez-Quiles, MD; Schooler, NR, 1994)
"Randomised controlled trials (RCTs) involving people exhibiting aggression and/or agitation thought to be due to psychosis, allocated rapid use of haloperidol alone (by any route), compared with any other treatment."4.95Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation). ( Adams, CE; Brooke-Powney, MJ; Li, X; Ostinelli, EG, 2017)
"To evaluate the clinical effects of haloperidol for the management of schizophrenia and other similar serious mental illnesses compared with placebo."4.89Haloperidol versus placebo for schizophrenia. ( Adams, CE; Bergman, H; Irving, CB; Lawrie, S, 2013)
"Randomised controlled  trials (RCTs) involving people exhibiting agitation or aggression (or both) thought to be due to psychosis, allocated rapid use of haloperidol alone (by any route), compared with any other treatment."4.88Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation). ( Adams, CE; Jones, H; Powney, MJ, 2012)
"Clinical safety data for treatment of acute schizophrenia with olanzapine, a new atypical antipsychotic agent, are summarized."4.79Safety of olanzapine. ( Beasley, CM; Tollefson, GD; Tran, PV, 1997)
"A 28-year-old woman presenting with agitation and mania with psychotic features developed symptoms of isolated lingual dystonia shortly after the initiation of a haloperidol concentrate regimen."4.02Haloperidol-induced isolated lingual dystonia. ( Chapa, A; Helminiak, A; Jin, JW; Kockara, N, 2021)
" When the diagnosis of haloperidol-induced acute dystonia was made, 3 mg of intravenous biperiden was promptly administered with complete clinical resolution in 15 min."3.91Involuntary movements in an adolescent: what are the causes? ( Brito, N; Fernandes, A; Moura, L; Vaz, AS, 2019)
" He had relapse symptoms of schizophrenia and had recently received a single dose of parenteral haloperidol to manage his agitation."3.85Persistent oromandibular dystonia and angioedema secondary to haloperidol. ( Masiran, R, 2017)
"We discus the case of a forty-nine year old patient with haloperidol induced laryngeal dystonia (LD)."3.74A patient with haloperidol induced laryngeal dystonia. ( Peek, DF, 2008)
"To report a case of delayed-onset dystonic reactions, oculogyric crisis (OGC), and torticollis after treatment with intramuscular haloperidol lactate injection."3.72Delayed onset of oculogyric crisis and torticollis with intramuscular haloperidol. ( Jhee, SS; Mohaupt, SM; Sims, SJ; Yones, CL; Zarotsky, V, 2003)
"Although diphenhydramine hydrochloride is known to eliminate or reduce the symptoms of dystonia in human patients with acute dystonic reactions and idiopathic torsion dystonia, its mechanism of action is still unclear."3.69Evidence for the involvement of histamine in the antidystonic effects of diphenhydramine. ( Matsumoto, RR; Stone, MR; Truong, DD; van't Groenewout, JL; Vo, VN, 1995)
" Recent studies in mutant dystonic hamsters (dt[sz]), an animal model of idiopathic generalized dystonia, revealed antidystonic effects of both N-methyl-D-aspartate (NMDA) receptor antagonists, such as dizocilpine (MK-801), and of neuroleptics, such as haloperidol and clozapine."3.69MK-801 potentiates antidystonic effects of clozapine but not of haloperidol in mutant dystonic hamsters. ( Löscher, W; Richter, A, 1997)
"The patient was a 24-year-old man with recently diagnosed schizophrenia who presented twice to a general hospital with difficulty speaking within 72 hours of increasing his dose of haloperidol."3.69Neuroleptic-induced laryngeal dystonia can mimic anaphylaxis. ( Ilchef, R, 1997)
"To examine whether acute dystonia is induced by neuroleptic treatment, common marmosets were treated with haloperidol orally twice a week over 25 weeks until dystonic behavior was elicited."3.69The common marmoset (Callithrix jacchus) as a model for neuroleptic-induced acute dystonia. ( Fukuoka, T; Kohda, A; Matsuo, M; Nakano, M; Okuno, Y, 1997)
"The effects of the atypical neuroleptic clozapine were studied in an inbred line of Syrian golden hamsters with generalized dystonia, i."3.68The atypical neuroleptic, clozapine, exerts antidystonic activity in a mutant hamster model. Comparison with haloperidol. ( Löscher, W; Richter, A, 1993)
" The dopamine precursor levodopa (injected together with carbidopa) and the dopamine receptor agonist apomorphine increased the severity of dystonia in hamsters when administered prior to the age of maximum severity of dystonia."3.68Effects of pharmacological manipulation of dopaminergic and cholinergic neurotransmission in genetically dystonic hamsters. ( Fredow, G; Löscher, W, 1992)
"From among 1377 patients with movement disorders, four patients had an unusual movement disorder characterised by paroxysmal bursts of involuntary, regular, repetitive, rhythmic, bilateral, coordinated, simultaneous, stereotypic myoclonus and vocalisations, often associated with tonic symptoms, interference with voluntary functioning, presence of hyperactivity, attention and learning disabilities, and resistance to treatment with haloperidol and other drugs."3.67Paroxysmal myoclonic dystonia with vocalisations: new entity or variant of preexisting syndromes? ( Feinberg, TE; Shapiro, AK; Shapiro, E, 1986)
" Therefore, we have studied the effect of different 5-HT drugs and one anticholinergic drug in acute dystonia in five cebus monkeys chronically treated with haloperidol."3.67Effects of serotonergic and anticholinergic drugs in haloperidol-induced dystonia in Cebus monkeys. ( Gerlach, J; Korsgaard, S; Laursen, AL; Noring, U; Povlsen, UJ, 1986)
" In this retrospective study, 15 of 16 young adult patients treated only with haloperidol had such reactions within 60 hours of beginning the drug, while none of the seven patients treated with haloperidol plus prophylactic benztropine mesylate developed dystonia."3.67Anticholinergic prophylaxis of acute haloperidol-induced acute dystonic reactions. ( Bakalar, NH; Boyer, WF; Lake, CR, 1987)
"The use of baclofen, a structural analog of gamma-aminobutyric acid (GABA), is described in the treatment of a patient with tardive dystonia."3.67Baclofen treatment in a patient with tardive dystonia. ( Allen, A; Lux, WE; Rosse, RB, 1986)
" SCH 23390 (a selective D1 antagonist) and raclopride (a selective D2 antagonist) induced identical syndromes consisting of dystonia and oral dyskinesia."3.67Selective D1 and D2 receptor manipulation in Cebus monkeys: relevance for dystonia and dyskinesia in humans. ( Gerlach, J; Kistrup, K, 1987)
" To clarify the etiology of neuroleptic-induced acute dystonic reactions, monkeys (Cercopithecus aethiops) were treated with haloperidol at doses sufficient to evoke dystonia, and the effects of agents that influenced dopaminergic, cholinergic, or GABAergic neurotransmitters were evaluated."3.66Dopamine, acetylcholine, and GABA effects in acute dystonia in primates. ( Casey, DE; Christensson, E; Gerlach, J, 1980)
" Case 1 is a description of the subjective experience of a patient with acute orofacial dystonia from promethazine."3.66Case vignettes of movement disorders. ( Yung, CY, 1983)
" Sample size was reduced from 311 to 156 patients, thereby decreasing the number of patients exposed to placebo from 54 to 30 and the number exposed to the active control with a known side effect from 126 to 60."2.74Bayesian adaptive non-inferiority with safety assessment: retrospective case study to highlight potential benefits and limitations of the approach. ( Baker, R; Breier, A; Dunayevich, E; Lindborg, S; Seaman, J; Spann, M, 2009)
"We have presented pharmacokinetic parameters of bromperidol (BP) in 14 healthy Korean subjects."2.72Pharmacokinetic parameters of bromperidol in Korean subjects. ( Kim, HG; Kim, JW; Kim, YG; Lee, SY, 2006)
"An eleven-fold increase in dystonia was found in patients who received no prophylactic medication."2.65Benztropine prophylaxis of dystonic reactions. ( Anderson, WH; Stern, TA, 1979)
"Antipsychotic-induced laryngeal dystonia is a life-threatening side-effect of both high- and low-potency classical antipsychotics, and its diagnosis often remains elusive."2.43Antipsychotic drug-induced acute laryngeal dystonia: two case reports and a mini review. ( Christodoulou, C; Kalaitzi, C, 2005)
"Risperidone has these pharmacologic properties."2.39Extrapyramidal side effects and tolerability of risperidone: a review. ( Owens, DG, 1994)
"Acute dystonia can also be reliably induced in many primate species by neuroleptic treatment with comparable time course, symptomatology and pharmacological characteristics to those observed in man."2.37Acute dystonia induced by neuroleptic drugs. ( Jenner, P; Marsden, CD; Rupniak, NM, 1986)
"Most cases of acute dystonia are mild and easy to manage; nevertheless, some of them can be fatal because of the involvement of certain muscle groups such as the laryngeal muscles, thus requiring urgent intervention."1.39Is acute dystonia an emergency? Sometimes, it really is! ( Cizmeci, MN; Derinoz, O; Havali, C; Kanburoglu, MK, 2013)
"Oromandibular dystonia is a subtype of dystonia which can present with perioral manifestations."1.38Bilateral dislocation of temporomandibular joint induced by haloperidol following suicide attempt: a case report. ( Arghand Dargahi, M; Tabatabaiefar, MA; Taslimi, S; Zakariaei, Z, 2012)
"Depressed levels of consciousness and dystonia were the most common presenting signs, present in 90."1.31Phenothiazine, butyrophenone, and other psychotropic medication poisonings in children and adolescents. ( Abel, K; James, LP; Nichols, MH; Simpson, PM; Wilkinson, J, 2000)
"Acute dystonia developed in 10 of 33 patients, and the mean age was significantly lower (P < 0."1.31The characteristics of side-effects of bromperidol in schizophrenic patients. ( Ishida, M; Kaneko, S; Kondo, T; Mihara, K; Otani, K; Tanaka, O; Yasui-Furukori, N, 2002)
"Dopa-responsive dystonia, an autosomal-dominant disorder caused by mutations in the guanosine triphosphate (GTP)-cyclohydrolase I gene, is characterized by severe striatal dopamine depletion."1.30Tardive dyskinesia in dopa-responsive dystonia: a reappraisal of the dopamine hypothesis of tardive dyskinesia. ( de la Fuente-Fernández, R, 1998)
"Tardive dystonia is a difficult condition to treat."1.30Treatment of tardive dystonia with an antispastic agent. ( Ishiguro, T; Nisijima, K; Shimizu, M, 1998)
"Extrapyramidal symptoms (EPS) of dystonia and sedation were scored daily."1.29The effects of D1 (NNC 22-0215) and D2 (haloperidol) antagonists in a chronic double-blind placebo controlled trial in cebus monkeys. ( Casey, DE, 1995)
"One of the patients developed dystonia 24 hours after ingestion of 750 mg tetrabenazine in an attempt at suicide."1.29[Drug-induced dystonia misinterpreted as hysteria]. ( Dietrichs, E; Magnusson, A; Opjordsmoen, S, 1996)
"Haloperidol and perphenazine induced dystonia in the same way as sigma receptor agonists, whereas zotepine and (-)-sulpiride did not."1.29BMY-14802 reversed the sigma receptor agonist-induced neck dystonia in rats. ( Akiyama, K; Kuroda, S; Okumura, K; Ujike, H, 1996)
"This form of dystonia is called tardive dystonia to distinguish it from tardive dyskinesia."1.29[Tardive dystonia. A rare neuroleptic-induced disease picture]. ( Assion, HJ; Heinemann, F, 1994)
"Neither (-)-3-PPP nor SND 919 produced dystonia, but had observable dopamine D2 receptor agonistic effects, (-)-3-PPP producing emesis at 1-4 mg/kg and SND 919 producing motoric unrest and stereotypy at 0."1.29Effects of several partial dopamine D2 receptor agonists in Cebus apella monkeys previously treated with haloperidol. ( Gerlach, J; Peacock, L, 1993)
"Haloperidol was implicated in 47 patients (37%), followed by amitriptyline/perphenazine in 30%, thioridazine in 27%, and chlorpromazine in 20%."1.28Neurologic approach to drug-induced movement disorders: a study of 125 patients. ( Jankovic, J; Miller, LG, 1990)
"Then at the age of eight, she developed dystonia of the left lower extremity that became noticeable toward evening but subsided after taking sleep."1.28[Response to haloperidol and analysis of growth curve in hereditary progressive dystonia with marked diurnal fluctuation]. ( Cho, K; Kusunoki, Y; Oki, J; Sasaki, N, 1989)
"Rhabdomyolysis is a rarely reported complication of antipsychotic drug-induced dystonia."1.27Rhabdomyolysis due to acute dystonic reaction to antipsychotic drugs. ( Cavanaugh, JJ; Finlayson, RE, 1984)
" Data were analyzed to determine the effect of anticholinergic prophylaxis, age, sex, and type and dosage of neuroleptic on the incidence of dystonic reactions."1.27Anticholinergic agents for prophylaxis of neuroleptic-induced dystonic reactions: a prospective study. ( Heiser, JF; Morrison, RL; Simpson, GM; Sramek, JJ, 1986)
"Attacks of acute dystonia have been noticed in all animals, sometimes necessitating anticholinergic medication or decreases in the daily haloperidol dose."1.26Development of acute dystonia and tardive dyskinesia in cebus monkeys. ( Bárány, S; Gunne, LM; Ingvast, A, 1979)

Research

Studies (112)

TimeframeStudies, this research(%)All Research%
pre-199040 (35.71)18.7374
1990's41 (36.61)18.2507
2000's20 (17.86)29.6817
2010's10 (8.93)24.3611
2020's1 (0.89)2.80

Authors

AuthorsStudies
Jin, JW1
Chapa, A1
Kockara, N1
Helminiak, A1
Vaz, AS1
Brito, N1
Moura, L1
Fernandes, A1
Ostinelli, EG1
Brooke-Powney, MJ1
Li, X1
Adams, CE3
Masiran, R1
Kanburoglu, MK1
Derinoz, O1
Cizmeci, MN1
Havali, C1
Bergman, H1
Irving, CB1
Lawrie, S1
Rasmussen, SA1
Rosebush, PI1
Mazurek, MF1
Ridout, KK1
Ridout, SJ1
Peek, DF1
Spann, M1
Lindborg, S1
Seaman, J1
Baker, R1
Dunayevich, E1
Breier, A1
Chen, L2
Wang, HT1
Han, XH1
Li, YL1
Cui, QL2
Xie, JX2
Yagmur, F1
Ulusoy, HB1
Buyukoglan, H1
Kaya, MG1
Zakariaei, Z1
Taslimi, S1
Tabatabaiefar, MA1
Arghand Dargahi, M1
Powney, MJ1
Jones, H1
Torner, C1
Herrera-Estrella, M1
Gutiérrez, JA1
Aguilar-Roblero, R1
FIERLAFIJN, E1
Barnes Recker, CK1
Hoehns, JD1
Sutherland, JE1
Opheim, EF1
Jhee, SS1
Zarotsky, V1
Mohaupt, SM1
Yones, CL1
Sims, SJ1
Hamann, M1
Meisler, MH1
Richter, A3
Martínez Fernández, G1
Plaza Moral, A1
Miró Descarga, P1
Arguís Gimeno, MJ1
Gomar Sancho, C1
Christodoulou, C1
Kalaitzi, C1
Chakravarty, A1
Lee, SY1
Kim, YG1
Kim, HG1
Kim, JW1
Xue, Y1
Yung, WH1
Praharaj, SK1
Arora, M1
Sari, A1
Akkaya, C1
Taskapilioglu, O1
Erer, S1
Bora, I1
Gross, ML1
Stahl, SM1
Berger, PA1
Fritze, J1
Conn, LM1
Lion, JR1
Campbell, M1
Small, AM1
Green, WH1
Jennings, SJ1
Perry, R1
Bennett, WG1
Anderson, L1
McKeon, TW1
Lorden, JF2
Oltmans, GA1
Beales, M1
Walkley, SU1
Yung, CY1
Ortiz, A1
Castillo, J1
Castro, A1
Dapena, D1
Arias, M1
Colell, S1
Lema, M1
Noya, M1
Cavanaugh, JJ1
Finlayson, RE1
Casey, DE4
Gerlach, J4
Christensson, E1
Town, IG1
McDanal, CE1
Bryant, SG1
Menuck, M1
Owens, DG1
van't Groenewout, JL1
Stone, MR1
Vo, VN2
Truong, DD2
Matsumoto, RR3
Factor, SA1
Podskalny, GD1
Barron, KD1
Assion, HJ1
Heinemann, F1
Capstick, C1
Checkley, S1
Gray, J1
Dawe, S1
Aguilar, EJ1
Keshavan, MS1
Martínez-Quiles, MD1
Hernández, J1
Gómez-Beneyto, M1
Schooler, NR1
Khanna, R1
Damodaran, SS1
Chakraborty, SP1
Peacock, L1
Löscher, W3
Kastrup, O1
Gastpar, M1
Schwarz, M1
Lindenmeyer, JP1
Magnusson, A1
Opjordsmoen, S1
Dietrichs, E1
Tarsy, D1
Miyawaki, E1
Bowen, WD2
Walker, JM2
Patrick, SL1
Zambon, AC1
De Costa, BR1
Rice, KC1
Raja, M1
Maisto, G1
Altavista, MC1
Albanese, A1
Okumura, K1
Ujike, H1
Akiyama, K1
Kuroda, S1
Fang, J1
Beasley, CM1
Tollefson, GD1
Tran, PV1
Modrego Pardo, P1
Pérez Trullen, JM1
Fukuoka, T1
Nakano, M1
Kohda, A1
Okuno, Y1
Matsuo, M1
Ilchef, R1
de la Fuente-Fernández, R1
Black, KJ1
Racette, B1
Perlmutter, JS1
Nisijima, K1
Shimizu, M1
Ishiguro, T1
Gannon, MA1
O'Sullivan, P1
Fines, RE1
Brady, WJ1
Martin, ML1
Rojas, VM1
Davies, RK1
Miwa, H1
Nishi, K1
Fuwa, T1
Mizuno, Y1
James, LP1
Abel, K1
Wilkinson, J1
Simpson, PM1
Nichols, MH1
Vogler, CM1
Szonyli, G1
Munro, P1
Cusack, S1
Yasui-Furukori, N1
Kondo, T1
Ishida, M1
Tanaka, O1
Mihara, K1
Kaneko, S1
Otani, K1
Hendrickson, RG1
Morocco, AP1
Greenberg, MI1
Stern, TA1
Anderson, WH1
Bárány, S1
Ingvast, A1
Gunne, LM1
Calne, DB1
Eisler, T1
Godwin-Austen, RB1
Cavenar, JO1
Hammett, EB1
Maltbie, A1
Lee, AS1
Di Monda, V1
Fazzari, G1
Callea, L1
Adlmici, G1
Sinaniotis, CA1
Spyrides, P1
Vlachos, P1
Papadatos, C1
Suzuki, E1
Kanba, S1
Nibuya, M1
Shintani, F1
Kinoshita, N1
Yagi, G1
Asai, M1
Fredow, G1
Meltzer, LT1
Christoffersen, CL1
Serpa, KA1
Pugsley, TA1
Razmpour, A1
Heffner, TG1
Lauterbach, EC1
Verhoeff, NP1
Wasserstein, PH1
Honig, LS1
Sandyk, R1
Miller, LG1
Jankovic, J1
Remington, GJ1
Voineskos, G1
Pollock, B1
Reed, K1
Coulter, K1
Stevens, CB1
Friedman, EH1
Mackler, S1
Moskowitz, M1
Oki, J1
Sasaki, N1
Kusunoki, Y1
Cho, K1
Heintz, R1
Yashar, AG1
Walker, FO1
Rupniak, NM1
Jenner, P1
Marsden, CD1
Sramek, JJ1
Simpson, GM1
Morrison, RL1
Heiser, JF1
Kumor, K1
Sherer, M1
Jaffe, J1
Kistrup, K1
Addonizio, G1
Alexopoulos, GS1
Davidson, M1
Powchik, P1
Davis, KL1
Feinberg, TE1
Shapiro, AK1
Shapiro, E1
Povlsen, UJ1
Noring, U1
Laursen, AL1
Korsgaard, S1
Conacher, GN1
Marazki, MO1
Evans, DA1
Bertilsson, L1
Sjoqvist, F1
Boyer, WF1
Bakalar, NH1
Lake, CR1
Rosse, RB1
Allen, A1
Lux, WE1
Bateman, DN1
Rawlins, MD1
Simpson, JM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Placebo-Controlled, Cross-Over Trial of Aripiprazole Added to Obese Olanzapine-Treated Patients With Schizophrenia[NCT00351936]Phase 416 participants (Actual)Interventional2005-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in Body Mass Index (BMI)

Evaluating change in Body Mass Index (BMI) between Baseline and Week 4, comparing subjects treated with aripiprazole for 4 weeks to subjects treated with placebo for 4 weeks. (NCT00351936)
Timeframe: baseline, week 4

Interventionkg/m^2 (Mean)
Aripiprazole-0.4
Placebo0.3

Change From Baseline in Fasting Total Cholesterol

Evaluating change in fasting total cholesterol between Baseline and Week 4, comparing subjects treated with aripiprazole for 4 weeks to subjects treated with placebo for 4 weeks. (NCT00351936)
Timeframe: baseline, week 4

Interventionmg/dL (Mean)
Aripiprazole-3
Placebo9

Change From Baseline in High-density Lipoprotein Cholesterol (HDL-C)

Evaluating change in high-density lipoprotein cholesterol (HDL-C) between Baseline and Week 4, comparing subjects treated with aripiprazole for 4 weeks to subjects treated with placebo for 4 weeks. (NCT00351936)
Timeframe: baseline, week 4

Interventionmg/dL (Mean)
Aripiprazole0.4
Placebo0.6

Change From Baseline in Low-density Lipoprotein (LDL)

Evaluating change in low-density lipoprotein (LDL) between Baseline and Week 4, comparing subjects treated with aripiprazole for 4 weeks to subjects treated with placebo for 4 weeks. (NCT00351936)
Timeframe: baseline, week 4

Interventionmg/dL (Mean)
Aripiprazole-0.2
Placebo3.1

Change From Baseline in Triglycerides

Evaluating change in triglyceride levels between Baseline and Week 4, comparing subjects treated with aripiprazole for 4 weeks to subjects treated with placebo for 4 weeks. (NCT00351936)
Timeframe: baseline, week 4

Interventionmg/dL (Mean)
Aripiprazole-51.7
Placebo47.6

Change From Baseline in Waist-hip Ratio (WHR)

Evaluating change in waist-hip ratio (WHR) between Baseline and Week 4, comparing subjects treated with aripiprazole for 4 weeks to subjects treated with placebo for 4 weeks. (NCT00351936)
Timeframe: baseline, week 4

Interventioncm (Mean)
Aripiprazole0.0
Placebo0.0

Change From Baseline in Weight (Lbs)

Evaluating change in weight (lbs) between Baseline and Week 4, comparing subjects treated with aripiprazole for 4 weeks to subjects treated with placebo for 4 weeks. (NCT00351936)
Timeframe: baseline, week 4

Interventionlbs (Mean)
Aripiprazole-2.9
Placebo2.1

Reviews

9 reviews available for haloperidol and Dystonia

ArticleYear
Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation).
    The Cochrane database of systematic reviews, 2017, 07-31, Volume: 7

    Topics: Aggression; Antipsychotic Agents; Dystonia; Haloperidol; Humans; Hypnotics and Sedatives; Placebos;

2017
Haloperidol versus placebo for schizophrenia.
    The Cochrane database of systematic reviews, 2013, Nov-15, Issue:11

    Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Dystonia; Haloperidol; Humans; Parkinsonian Disorders

2013
Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation).
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Aggression; Antipsychotic Agents; Aripiprazole; Clopenthixol; Dystonia; Haloperidol; Humans; Lorazep

2012
Antipsychotic drug-induced acute laryngeal dystonia: two case reports and a mini review.
    Journal of psychopharmacology (Oxford, England), 2005, Volume: 19, Issue:3

    Topics: Adult; Antipsychotic Agents; Diagnosis, Differential; Dystonia; Female; Haloperidol; Humans; Larynge

2005
Pharmacologic approaches to violence.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:4

    Topics: Aggression; Anticonvulsants; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Be

1984
Extrapyramidal side effects and tolerability of risperidone: a review.
    The Journal of clinical psychiatry, 1994, Volume: 55 Suppl

    Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Clinical Trials as Topic; Dyskinesia, Drug-Induced; D

1994
Safety of olanzapine.
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 10

    Topics: Acute Disease; Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Blood Pressure; Clini

1997
The pathogensis and medical treatment of extrapyramidal disease.
    The Medical clinics of North America, 1979, Volume: 63, Issue:4

    Topics: Adult; Athetosis; Basal Ganglia Diseases; Caudate Nucleus; Chorea; Corpus Striatum; Dopamine; Dopami

1979
Acute dystonia induced by neuroleptic drugs.
    Psychopharmacology, 1986, Volume: 88, Issue:4

    Topics: Acute Disease; alpha-Methyltyrosine; Animals; Antipsychotic Agents; Brain; Chlorpromazine; Disease M

1986

Trials

7 trials available for haloperidol and Dystonia

ArticleYear
Bayesian adaptive non-inferiority with safety assessment: retrospective case study to highlight potential benefits and limitations of the approach.
    Journal of psychiatric research, 2009, Volume: 43, Issue:5

    Topics: Antipsychotic Agents; Bayes Theorem; Benzodiazepines; Double-Blind Method; Drug-Related Side Effects

2009
Diurnal variations of extrapyramidal symptoms induced by haloperidol in schizophrenic subjects.
    The international journal of neuropsychopharmacology, 2003, Volume: 6, Issue:3

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Basal Ganglia Diseases; Circadian Rhythm; Cros

2003
Pharmacokinetic parameters of bromperidol in Korean subjects.
    Human psychopharmacology, 2006, Volume: 21, Issue:6

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A

2006
Bromocriptine, physostigmine, and neurotransmitter mechanisms in the dystonias.
    Neurology, 1982, Volume: 32, Issue:8

    Topics: Adult; Bromocriptine; Child; Clinical Trials as Topic; Dose-Response Relationship, Drug; Dystonia; F

1982
Behavioral efficacy of haloperidol and lithium carbonate. A comparison in hospitalized aggressive children with conduct disorder.
    Archives of general psychiatry, 1984, Volume: 41, Issue:7

    Topics: Aggression; Child; Child Behavior Disorders; Clinical Trials as Topic; Depressive Disorder; Double-B

1984
Predictors of acute dystonia in first-episode psychotic patients.
    The American journal of psychiatry, 1994, Volume: 151, Issue:12

    Topics: Adolescent; Adult; Age Factors; Biperiden; Delusions; Double-Blind Method; Dystonia; Female; Haloper

1994
Benztropine prophylaxis of dystonic reactions.
    Psychopharmacology, 1979, Mar-28, Volume: 61, Issue:3

    Topics: Adult; Aged; Antipsychotic Agents; Benztropine; Clinical Trials as Topic; Dystonia; Female; Haloperi

1979

Other Studies

96 other studies available for haloperidol and Dystonia

ArticleYear
Haloperidol-induced isolated lingual dystonia.
    BMJ case reports, 2021, Oct-05, Volume: 14, Issue:10

    Topics: Adult; Dystonia; Dystonic Disorders; Female; Haloperidol; Humans

2021
Involuntary movements in an adolescent: what are the causes?
    BMJ case reports, 2019, Dec-10, Volume: 12, Issue:12

    Topics: Adolescent; Alcoholic Intoxication; Antipsychotic Agents; Biperiden; Dystonia; Emergency Service, Ho

2019
Persistent oromandibular dystonia and angioedema secondary to haloperidol.
    BMJ case reports, 2017, Oct-04, Volume: 2017

    Topics: Adult; Angioedema; Antipsychotic Agents; Diagnosis, Differential; Dystonia; Haloperidol; Humans; Mal

2017
Is acute dystonia an emergency? Sometimes, it really is!
    Pediatric emergency care, 2013, Volume: 29, Issue:3

    Topics: Acute Disease; Adolescent; Antipsychotic Agents; Biperiden; Chlorpromazine; Diagnosis, Differential;

2013
The Relationship Between Early Haloperidol Response and Associated Extrapyramidal Side Effects.
    Journal of clinical psychopharmacology, 2017, Volume: 37, Issue:1

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Brief Psychiatric Rating Scale; Dyskinesia, Dr

2017
Haloperidol-Associated Uterine Dystonia.
    The American journal of psychiatry, 2017, 03-01, Volume: 174, Issue:3

    Topics: Antipsychotic Agents; Anxiety Disorders; Dystonia; Female; Haloperidol; Humans; Pregnancy; Uterine D

2017
A patient with haloperidol induced laryngeal dystonia.
    Acta anaesthesiologica Belgica, 2008, Volume: 59, Issue:2

    Topics: Antipsychotic Agents; Dystonia; Haloperidol; Humans; Laryngeal Diseases; Male; Middle Aged; Respirat

2008
Behavioral and electrophysiological effects of pallidal GABAB receptor activation and blockade on haloperidol-induced akinesia in rats.
    Brain research, 2008, Dec-09, Volume: 1244

    Topics: Animals; Baclofen; Behavior, Animal; Dopamine Antagonists; Dystonia; Electrophysiology; Excitatory P

2008
Acute respiratory distress due to antipsychotic drugs.
    Pharmacopsychiatry, 2010, Volume: 43, Issue:3

    Topics: Adult; Antiparkinson Agents; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Drug Therapy, Co

2010
Bilateral dislocation of temporomandibular joint induced by haloperidol following suicide attempt: a case report.
    Acta medica Iranica, 2012, Volume: 50, Issue:3

    Topics: Adolescent; Dopamine Antagonists; Dystonia; Female; Haloperidol; Humans; Joint Dislocations; Suicide

2012
[HP 32, COMBINATION OF R 1625 (HALOPERIDOL) AND R 79 (ISOPROPAMIDE IODIDE) IN THE THERAPY OF PSYCHIC AND AUTONOMIC DYSTONIA].
    Bruxelles medical, 1963, Sep-29, Volume: 43

    Topics: Autonomic Nervous System Diseases; Dystonia; Dystonic Disorders; Haloperidol; Parasympatholytics; Ps

1963
An online misadventure with haloperidol.
    The Annals of pharmacotherapy, 2003, Volume: 37, Issue:10

    Topics: Acetaminophen; Administration, Oral; Adult; Azepines; Codeine; Drug Combinations; Dystonia; Female;

2003
Delayed onset of oculogyric crisis and torticollis with intramuscular haloperidol.
    The Annals of pharmacotherapy, 2003, Volume: 37, Issue:10

    Topics: Adult; Dystonia; Female; Haloperidol; Humans; Injections, Intramuscular; Ocular Motility Disorders;

2003
Motor disturbances in mice with deficiency of the sodium channel gene Scn8a show features of human dystonia.
    Experimental neurology, 2003, Volume: 184, Issue:2

    Topics: Animals; Anti-Dyskinesia Agents; Anticonvulsants; Biperiden; Brain; Diazepam; Disease Models, Animal

2003
[Acute dystonia due to haloperidol during labor].
    Revista espanola de anestesiologia y reanimacion, 2004, Volume: 51, Issue:4

    Topics: Acute Disease; Adult; Dystonia; Female; Haloperidol; Humans; Obstetric Labor Complications; Pregnanc

2004
Neuroleptic-induced acute laryngeal dystonia causing stridor: a lesson to remember.
    Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20, Issue:8

    Topics: Antipsychotic Agents; Dystonia; Haloperidol; Humans; Laryngeal Diseases; Male; Respiratory Sounds; S

2005
Electrophysiological and behavioral effects of neurotensin in rat globus pallidus: an in vivo study.
    Experimental neurology, 2007, Volume: 205, Issue:1

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Dose-Response Relationship, Drug; Drug Synergism; D

2007
Pisa syndrome: acute and tardive forms.
    Southern medical journal, 2007, Volume: 100, Issue:8

    Topics: Adult; Antipsychotic Agents; Dyskinesia, Drug-Induced; Dystonia; Haloperidol; Humans; Male; Schizoph

2007
Laryngeal dystonia in a patient with bilateral anterior cerebral artery infarction during treatment of delirium with haloperidol.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Jul-01, Volume: 32, Issue:5

    Topics: Antipsychotic Agents; Delirium; Dystonia; Haloperidol; Humans; Infarction, Anterior Cerebral Artery;

2008
Acute dystonia as idiosyncratic reaction to haloperidol.
    Lancet (London, England), 1980, Aug-30, Volume: 2, Issue:8192

    Topics: Acute Disease; Child; Dystonia; Female; Haloperidol; Humans; Hypertension

1980
Can neuroleptics influence the function of the brain hemispheres asymmetrically?
    Neuropharmacology, 1984, Volume: 23, Issue:1

    Topics: Animals; Antipsychotic Agents; Brain; Carotid Arteries; Clopenthixol; Dystonia; Flupenthixol; Functi

1984
Decreased catalepsy response to haloperidol in the genetically dystonic (dt) rat.
    Brain research, 1984, Aug-06, Volume: 308, Issue:1

    Topics: 4-Butyrolactone; Aging; Animals; Brain; Catalepsy; Corpus Striatum; Dopamine; Dystonia; Golgi Appara

1984
Case vignettes of movement disorders.
    Brain research bulletin, 1983, Volume: 11, Issue:2

    Topics: Adult; Amantadine; Brain Injuries; Clonazepam; Diagnosis, Differential; Dystonia; Female; Haloperido

1983
Neuropharmacological profile of Meige's disease: overview and a case report.
    Clinical neuropharmacology, 1983, Volume: 6, Issue:4

    Topics: Aged; Baclofen; Benztropine; Clonazepam; Doxepin; Drug Therapy, Combination; Dystonia; Facial Muscle

1983
[Clinical and electrophysiological study of idiopathic orofacial dystonia (Meige's disease or Brueghel syndrome)].
    Revista clinica espanola, 1984, Apr-30, Volume: 173, Issue:2

    Topics: Dystonia; Electromyography; Facial Expression; Facial Muscles; Female; Haloperidol; Humans; Hyperkin

1984
Rhabdomyolysis due to acute dystonic reaction to antipsychotic drugs.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:8

    Topics: Acute Disease; Adult; Dystonia; Haloperidol; Humans; Male; Muscles; Myoglobinuria; Psychotic Disorde

1984
Dopamine, acetylcholine, and GABA effects in acute dystonia in primates.
    Psychopharmacology, 1980, Volume: 70, Issue:1

    Topics: Acetylcholine; Animals; Chlorocebus aethiops; Dopamine; Dystonia; gamma-Aminobutyric Acid; Haloperid

1980
Haloperidol: neuroleptic malignant syndrome.
    The New Zealand medical journal, 1982, Mar-24, Volume: 95, Issue:704

    Topics: Adult; Dystonia; Haloperidol; Humans; Male; Muscle Rigidity; Syndrome

1982
Haloperidol and laryngeal-pharyngeal dystonia.
    The American journal of psychiatry, 1981, Volume: 138, Issue:9

    Topics: Adult; Dystonia; Female; Haloperidol; Humans; Laryngeal Diseases; Pharyngeal Diseases

1981
Street drug misrepresentation.
    JAMA, 1980, Nov-14, Volume: 244, Issue:19

    Topics: Adult; Diazepam; Drug-Related Side Effects and Adverse Reactions; Dystonia; Haloperidol; Humans; Ill

1980
Laryngeal-pharyngeal dystonia and haloperidol.
    The American journal of psychiatry, 1981, Volume: 138, Issue:3

    Topics: Adult; Dystonia; Haloperidol; Humans; Laryngeal Muscles; Male; Muscles; Pharyngeal Muscles

1981
Evidence for the involvement of histamine in the antidystonic effects of diphenhydramine.
    Experimental neurology, 1995, Volume: 134, Issue:2

    Topics: Animals; Diphenhydramine; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Halope

1995
Persistent neuroleptic-induced rigidity and dystonia in AIDS dementia complex: a clinico-pathological case report.
    Journal of the neurological sciences, 1994, Dec-01, Volume: 127, Issue:1

    Topics: Adult; AIDS Dementia Complex; Antipsychotic Agents; Astrocytes; Atrophy; Brain; Cell Count; Dystonia

1994
[Tardive dystonia. A rare neuroleptic-induced disease picture].
    Der Nervenarzt, 1994, Volume: 65, Issue:11

    Topics: Basal Ganglia; Basal Ganglia Diseases; Drug Therapy, Combination; Dystonia; Electromyography; Female

1994
Dystonia induced by amphetamine and haloperidol.
    The British journal of psychiatry : the journal of mental science, 1994, Volume: 165, Issue:2

    Topics: Adult; Amphetamine; Dose-Response Relationship, Drug; Drug Synergism; Dystonia; Female; Haloperidol;

1994
Overflow movements may predict neuroleptic-induced dystonia.
    Biological psychiatry, 1994, Apr-01, Volume: 35, Issue:7

    Topics: Adolescent; Adult; Bipolar Disorder; Dyskinesia, Drug-Induced; Dystonia; Haloperidol; Humans; Male;

1994
Effects of several partial dopamine D2 receptor agonists in Cebus apella monkeys previously treated with haloperidol.
    European journal of pharmacology, 1993, Jun-24, Volume: 237, Issue:2-3

    Topics: Administration, Oral; Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Benzothiazoles;

1993
The atypical neuroleptic, clozapine, exerts antidystonic activity in a mutant hamster model. Comparison with haloperidol.
    European journal of pharmacology, 1993, Oct-05, Volume: 242, Issue:3

    Topics: Animals; Clozapine; Cricetinae; Disease Models, Animal; Dystonia; Female; Haloperidol; Male; Mesocri

1993
Acute dystonia due to clozapine.
    Journal of neurology, neurosurgery, and psychiatry, 1994, Volume: 57, Issue:1

    Topics: Acute Disease; Biperiden; Clozapine; Dystonia; Haloperidol; Humans; Male; Middle Aged; Schizophrenia

1994
Precipitation of dystonia by m-CPP in a schizophrenic patient treated with haloperidol.
    The American journal of psychiatry, 1993, Volume: 150, Issue:5

    Topics: Dystonia; Haloperidol; Humans; Male; Middle Aged; Piperazines; Schizophrenia, Paranoid; Serotonin; S

1993
The effects of D1 (NNC 22-0215) and D2 (haloperidol) antagonists in a chronic double-blind placebo controlled trial in cebus monkeys.
    Psychopharmacology, 1995, Volume: 121, Issue:3

    Topics: Administration, Oral; Animals; Cebus; Dopamine Antagonists; Dystonia; Haloperidol; Lactose; Receptor

1995
[Drug-induced dystonia misinterpreted as hysteria].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1996, Mar-10, Volume: 116, Issue:7

    Topics: Adrenergic Uptake Inhibitors; Adult; Antipsychotic Agents; Diagnosis, Differential; Dystonia; Female

1996
Tardive dystonia after neuroleptic treatment of Tourette's syndrome.
    Journal of neurology, neurosurgery, and psychiatry, 1996, Volume: 61, Issue:1

    Topics: Adult; Antipsychotic Agents; Dystonia; Haloperidol; Humans; Male; Tourette Syndrome

1996
Dissociation of the motor effects of (+)-pentazocine from binding to sigma 1 sites.
    European journal of pharmacology, 1996, Apr-22, Volume: 301, Issue:1-3

    Topics: Aging; Animals; Central Nervous System Depressants; Dystonia; Haloperidol; Head Movements; In Vitro

1996
Tardive lingual dystonia treated with clozapine.
    Movement disorders : official journal of the Movement Disorder Society, 1996, Volume: 11, Issue:5

    Topics: Adult; Antipsychotic Agents; Clozapine; Dystonia; Haloperidol; Humans; Male; Schizophrenia; Tongue

1996
BMY-14802 reversed the sigma receptor agonist-induced neck dystonia in rats.
    Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:10

    Topics: Animals; Antipsychotic Agents; Dibenzothiepins; Dopamine Antagonists; Dopamine D2 Receptor Antagonis

1996
Hyperactive behavioural effects induced by intranigral infusion of a pyridinium metabolite of haloperidol in rats.
    Canadian journal of physiology and pharmacology, 1996, Volume: 74, Issue:12

    Topics: Animals; Behavior, Animal; Dystonia; Haloperidol; Hyperkinesis; Injections, Intraventricular; Male;

1996
[Acute recurrent dystonia secondary to neuroleptic suppression].
    Revista clinica espanola, 1997, Volume: 197, Issue:3

    Topics: Acute Disease; Antipsychotic Agents; Dystonia; Haloperidol; Humans; Male; Middle Aged; Recurrence; S

1997
MK-801 potentiates antidystonic effects of clozapine but not of haloperidol in mutant dystonic hamsters.
    Brain research, 1997, Sep-26, Volume: 769, Issue:2

    Topics: Animals; Anti-Dyskinesia Agents; Catalepsy; Clozapine; Cricetinae; Dizocilpine Maleate; Drug Synergi

1997
The common marmoset (Callithrix jacchus) as a model for neuroleptic-induced acute dystonia.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 58, Issue:4

    Topics: Acute Disease; Animals; Antipsychotic Agents; Callithrix; Cholinergic Antagonists; Dose-Response Rel

1997
Neuroleptic-induced laryngeal dystonia can mimic anaphylaxis.
    The Australian and New Zealand journal of psychiatry, 1997, Volume: 31, Issue:6

    Topics: Acute Disease; Adult; Anaphylaxis; Antipsychotic Agents; Diagnosis, Differential; Dystonia; Haloperi

1997
Tardive dyskinesia in dopa-responsive dystonia: a reappraisal of the dopamine hypothesis of tardive dyskinesia.
    Neurology, 1998, Volume: 50, Issue:4

    Topics: Adult; Anti-Dyskinesia Agents; Dopamine; Dopamine Agents; Dyskinesia, Drug-Induced; Dystonia; Family

1998
Preventing contractures [correction of contractions] in neuroleptic malignant syndrome and dystonia.
    The American journal of psychiatry, 1998, Volume: 155, Issue:9

    Topics: Anti-Dyskinesia Agents; Botulinum Toxins; Combined Modality Therapy; Contracture; Dystonia; Female;

1998
Treatment of tardive dystonia with an antispastic agent.
    Acta psychiatrica Scandinavica, 1998, Volume: 98, Issue:4

    Topics: Adult; Anticonvulsants; Antipsychotic Agents; Dystonia; Female; Haloperidol; Humans; Propiophenones;

1998
Medical management of disturbed behaviour.
    Irish medical journal, 1998, Volume: 91, Issue:6

    Topics: Antidepressive Agents; Benzodiazepines; Bipolar Disorder; Chlorpromazine; Depressive Disorder; Dysto

1998
Acute laryngeal dystonia related to neuroleptic agents.
    The American journal of emergency medicine, 1999, Volume: 17, Issue:3

    Topics: Acute Disease; Adult; Antipsychotic Agents; Benzodiazepines; Diphenhydramine; Dystonia; Female; Halo

1999
Reserpine treatment of comorbid Tourette's disorder and tardive dystonia.
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:10

    Topics: Adrenergic Uptake Inhibitors; Adult; Comorbidity; Dyskinesia, Drug-Induced; Dystonia; Haloperidol; H

1999
Effects of blockade of metabotropic glutamate receptors in the subthalamic nucleus on haloperidol-induced Parkinsonism in rats.
    Neuroscience letters, 2000, Mar-17, Volume: 282, Issue:1-2

    Topics: Animals; Benzoates; Dopamine Antagonists; Dystonia; Excitatory Amino Acid Antagonists; Glycine; Halo

2000
Phenothiazine, butyrophenone, and other psychotropic medication poisonings in children and adolescents.
    Journal of toxicology. Clinical toxicology, 2000, Volume: 38, Issue:6

    Topics: Accidents, Home; Adolescent; Alabama; Antipsychotic Agents; Arkansas; Child; Child, Preschool; Dysto

2000
Laryngeal dystonia secondary to neuroleptic medications.
    The Medical journal of Australia, 2001, Oct-15, Volume: 175, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Benztropine; Dopamine Antagonists; Dystonia; Female; Follow-Up Studi

2001
Epidemic dystonia in Cork.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2001, Volume: 8, Issue:4

    Topics: Adolescent; Adult; Benztropine; Dystonia; Female; Haloperidol; Humans; Illicit Drugs; Ireland; Male;

2001
The characteristics of side-effects of bromperidol in schizophrenic patients.
    Psychiatry and clinical neurosciences, 2002, Volume: 56, Issue:1

    Topics: Adult; Antipsychotic Agents; Dystonia; Female; Haloperidol; Humans; Hypokinesia; Male; Schizophrenia

2002
Acute dystonic reactions to "street Xanax".
    The New England journal of medicine, 2002, May-30, Volume: 346, Issue:22

    Topics: Adolescent; Adult; Alprazolam; Child; Dystonia; Female; Haloperidol; Humans; Illicit Drugs; Male

2002
Development of acute dystonia and tardive dyskinesia in cebus monkeys.
    Research communications in chemical pathology and pharmacology, 1979, Volume: 25, Issue:2

    Topics: Animals; Dyskinesia, Drug-Induced; Dystonia; Haloperidol; Haplorhini; Motor Activity; Time Factors

1979
The treatment of the choreas and athetotic dystonias.
    Journal of the Royal College of Physicians of London, 1979, Volume: 13, Issue:1

    Topics: Adult; Athetosis; Benzodiazepines; Child; Chorea; Dystonia; Haloperidol; Humans; Levodopa; Movement

1979
Misdiagnosis of severe dystonia.
    Psychosomatics, 1979, Volume: 20, Issue:3

    Topics: Adult; Cerebral Hemorrhage; Diagnosis, Differential; Diagnostic Errors; Dystonia; Female; Haloperido

1979
Treatment of drug-induced dystonic reactions.
    JACEP, 1979, Volume: 8, Issue:11

    Topics: Adolescent; Adult; Benztropine; Diphenhydramine; Dystonia; Female; Haloperidol; Humans; Injections,

1979
[On a muscular dystony case from manganism. Therapeutic clinic considerations (author's transl)].
    L'Ateneo parmense. Acta bio-medica : organo della Societa di medicina e scienze naturali di Parma, 1979, Volume: 50, Issue:5-6

    Topics: Benserazide; Diazepam; Dystonia; Haloperidol; Humans; Hydrazines; Levodopa; Male; Manganese; Middle

1979
Acute haloperidol poisoning in children.
    The Journal of pediatrics, 1978, Volume: 93, Issue:6

    Topics: Acute Disease; Antiparkinson Agents; Basal Ganglia Diseases; Biperiden; Child; Child, Preschool; Dys

1978
Use of pimozide in the Pisa syndrome.
    The American journal of psychiatry, 1992, Volume: 149, Issue:8

    Topics: Adult; Dystonia; Haloperidol; Humans; Male; Pimozide; Receptors, Opioid; Receptors, sigma; Schizophr

1992
Effects of pharmacological manipulation of dopaminergic and cholinergic neurotransmission in genetically dystonic hamsters.
    European journal of pharmacology, 1992, Mar-17, Volume: 213, Issue:1

    Topics: Acetylcholine; Animals; Apomorphine; Behavior, Animal; Carbidopa; Cricetinae; Dopamine; Drug Interac

1992
Lack of involvement of haloperidol-sensitive sigma binding sites in modulation of dopamine neuronal activity and induction of dystonias by antipsychotic drugs.
    Neuropharmacology, 1992, Volume: 31, Issue:9

    Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Dopamine; Dystonia; Electrophysiology; Halope

1992
Haloperidol-induced dystonia and parkinsonism on discontinuing metoclopramide: implications for differential thalamocortical activity.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:6

    Topics: Adult; Brain; Drug Therapy, Combination; Dystonia; Female; Haloperidol; Humans; Metoclopramide; Park

1992
[The suppressed pill with far-reaching consequences].
    Nederlands tijdschrift voor geneeskunde, 1992, Mar-14, Volume: 136, Issue:11

    Topics: Dystonia; Haloperidol; Humans; Receptors, Dopamine; Receptors, Dopamine D2; Sulpiride; Tomography, E

1992
Dopamine D1 (SCH 23390) and D2 (haloperidol) antagonists in drug-naive monkeys.
    Psychopharmacology, 1992, Volume: 107, Issue:1

    Topics: Animals; Behavior, Animal; Benzazepines; Cebus; Dopamine Antagonists; Dose-Response Relationship, Dr

1992
Tic or dystonia?
    The Western journal of medicine, 1992, Volume: 156, Issue:6

    Topics: Adult; Diagnosis, Differential; Dystonia; Haloperidol; Humans; Tic Disorders; Torticollis

1992
Haloperidol-sensitive sigma receptor and the role of the pineal gland in dystonia.
    Schizophrenia research, 1991, Volume: 5, Issue:2

    Topics: Animals; Dystonia; Female; Haloperidol; Humans; Male; Pineal Gland; Rats; Receptors, Opioid; Recepto

1991
Neurologic approach to drug-induced movement disorders: a study of 125 patients.
    Southern medical journal, 1990, Volume: 83, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amitriptyline; Antipsychotic Agents; Chorea

1990
Prevalence of neuroleptic-induced dystonia in mania and schizophrenia.
    The American journal of psychiatry, 1990, Volume: 147, Issue:9

    Topics: Acute Disease; Adult; Antipsychotic Agents; Bipolar Disorder; Dose-Response Relationship, Drug; Drug

1990
Acute laryngeal dystonic reactions.
    Psychosomatics, 1990,Spring, Volume: 31, Issue:2

    Topics: Adult; Dystonia; Haloperidol; Humans; Laryngeal Diseases; Male; Respiratory Insufficiency

1990
Treatment of tardive dystonia.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:8

    Topics: Auditory Perceptual Disorders; Dystonia; Hallucinations; Haloperidol; Humans; Infant; Ocular Motilit

1990
Tetanus or drug reaction?
    Hospital practice (Office ed.), 1989, Aug-15, Volume: 24, Issue:8

    Topics: Adult; Aged; Diagnosis, Differential; Dystonia; Haloperidol; Humans; Immunization, Passive; Male; Te

1989
[Response to haloperidol and analysis of growth curve in hereditary progressive dystonia with marked diurnal fluctuation].
    No to hattatsu = Brain and development, 1989, Volume: 21, Issue:6

    Topics: Body Height; Child; Circadian Rhythm; Dystonia; Female; Haloperidol; Humans; Levodopa

1989
Pargyline reduces/prevents neuroleptic-induced acute dystonia in monkeys.
    Psychopharmacology, 1987, Volume: 93, Issue:2

    Topics: Animals; Basal Ganglia Diseases; Cebus; Corpus Striatum; Dopamine; Dystonia; Female; Haloperidol; Ma

1987
Altered haloperidol-sensitive sigma receptors in the genetically dystonic (dt) rat.
    European journal of pharmacology, 1988, Feb-16, Volume: 147, Issue:1

    Topics: Animals; Brain; Dystonia; Female; Haloperidol; Humans; In Vitro Techniques; Kinetics; Male; Rats; Ra

1988
Anticholinergic agents for prophylaxis of neuroleptic-induced dystonic reactions: a prospective study.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:6

    Topics: Adolescent; Adult; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Child; Chlorp

1986
Haloperidol-induced dystonia in cocaine addicts.
    Lancet (London, England), 1986, Dec-06, Volume: 2, Issue:8519

    Topics: Adult; Cocaine; Dystonia; Haloperidol; Humans; Male; Substance-Related Disorders

1986
Selective D1 and D2 receptor manipulation in Cebus monkeys: relevance for dystonia and dyskinesia in humans.
    Pharmacology & toxicology, 1987, Volume: 61, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Benzazepi

1987
Drug-induced dystonia in young and elderly patients.
    The American journal of psychiatry, 1988, Volume: 145, Issue:7

    Topics: Adult; Age Factors; Aged; Antipsychotic Agents; Chlorpromazine; Dystonia; Female; Fluphenazine; Halo

1988
Pisa syndrome in Alzheimer's disease.
    Biological psychiatry, 1988, Jan-15, Volume: 23, Issue:2

    Topics: Aged; Alzheimer Disease; Amantadine; Drug Therapy, Combination; Dystonia; Haloperidol; Humans; Male;

1988
Paroxysmal myoclonic dystonia with vocalisations: new entity or variant of preexisting syndromes?
    Journal of neurology, neurosurgery, and psychiatry, 1986, Volume: 49, Issue:1

    Topics: Adolescent; Adult; Child; Diagnosis, Differential; Dystonia; Female; Haloperidol; Humans; Male; Move

1986
Effects of serotonergic and anticholinergic drugs in haloperidol-induced dystonia in Cebus monkeys.
    Clinical neuropharmacology, 1986, Volume: 9, Issue:1

    Topics: Animals; Biperiden; Cebus; Citalopram; Dose-Response Relationship, Drug; Dystonia; Haloperidol; Male

1986
Acute dystonic reactions in Saudi Arabian psychiatric patients treated with haloperidol.
    Acta psychiatrica Scandinavica, 1987, Volume: 75, Issue:3

    Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Dystonia; Europe; Haloperidol; Humans; Middle A

1987
Anticholinergic prophylaxis of acute haloperidol-induced acute dystonic reactions.
    Journal of clinical psychopharmacology, 1987, Volume: 7, Issue:3

    Topics: Acute Disease; Adult; Benztropine; Drug Therapy, Combination; Dystonia; Female; Haloperidol; Humans;

1987
Baclofen treatment in a patient with tardive dystonia.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:9

    Topics: Aged; Alzheimer Disease; Baclofen; Dystonia; Female; Haloperidol; Humans

1986
Extrapyramidal reactions to prochlorperazine and haloperidol in the United Kingdom.
    The Quarterly journal of medicine, 1986, Volume: 59, Issue:230

    Topics: Adolescent; Adult; Age Factors; Basal Ganglia Diseases; Dyskinesia, Drug-Induced; Dystonia; Female;

1986