Page last updated: 2024-10-28

haloperidol and Depression, Involutional

haloperidol has been researched along with Depression, Involutional in 39 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Depression, Involutional: Form of depression in those MIDDLE AGE with feelings of ANXIETY.

Research Excerpts

ExcerptRelevanceReference
"To assess the benefit of short-term treatment with the atypical antipsychotic asenapine versus placebo on depressive symptoms in patients with acute schizophrenia in an exacerbated state."5.20Management of depressive symptoms in schizophrenia. ( Castle, DJ; Slott Jensen, JK, 2015)
"We followed up our initial results by in situ hybridization in subjects with schizophrenia, major depression, and a chronic haloperidol-treated nonhuman primate model."3.72Heat shock protein 12A shows reduced expression in the prefrontal cortex of subjects with schizophrenia. ( Levitt, P; Lewis, DA; Middleton, FA; Mirnics, K; Peng, L; Pongrac, JL, 2004)
"Neuroleptic malignant syndrome is a rare but potentially fatal complication of treatment with antipsychotic medications."2.41Neuroleptic malignant syndrome in children and adolescents. ( Rothner, AD; Ty, EB, 2001)
"Malignant catatonia is a life-threatening syndrome, associated mostly with psychiatric diseases but also with neurological and neurodegenerative syndromes."1.56[Malignant catatonia in dementia with Lewy Body successfully treated with sismotherapy: A case report]. ( Dhote, J; Gasnier, M; Kipman, A, 2020)
"Haloperidol was discontinued, but mirtazapine was continued, and the vivid dream activity persisted; however, reality testing when awake was intact."1.36Acute psychosis associated with dissociated sleep-wakefulness state after mirtazapine treatment. ( Felthous, AR; Hoevet, R; Wenger, PJ, 2010)
"A 72-year-old man with esophageal cancer who could not sit down or stand up was administered 5 mg/day haloperidol to relieve agitation as a symptom of major depressive disorder."1.36Diagnosis and treatment of akathisia in a cancer patient who cannot stand up or sit down, because of poor performance status: factors that make the diagnosis of akathisia difficult, and diagnosis clues. ( Ishida, M; Ito, H; Kawanishi, C; Mizuno, K; Narabayashi, M; Onishi, H; Sasaki, Y; Wada, M; Wada, T, 2010)
"Drug-induced delirium is a common matter in the elderly and anticholinergics, together with a number of different drugs, may significantly contribute to the delirium onset, especially in demented people."1.34Anticholinergic drug-induced delirium in an elderly Alzheimer's dementia patient. ( Cotroneo, A; De Fazio, P; De Fazio, S; De Sarro, G; Gallelli, L; Gareri, P; Lacava, R, 2007)
"Eight cases of glossodynia arising in the context of an endogenous depression are reported and the case histories of four of them are presented."1.27[Vital disorders of the mouth (glossodynia) in depressive involutional psychoses]. ( Maier, C, 1986)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199012 (30.77)18.7374
1990's1 (2.56)18.2507
2000's16 (41.03)29.6817
2010's8 (20.51)24.3611
2020's2 (5.13)2.80

Authors

AuthorsStudies
Léa Blondelle, KD1
Simplice, FH1
Hervé Hervé, NA1
Eglantine, KW1
Roland, RN1
Jorelle Linda, DK1
Balbine, KN1
Simon Désiré, GN1
Guillaume, CW1
Alin, C1
Dhote, J1
Kipman, A1
Gasnier, M1
Kennedy, SH1
Giacobbe, P1
Placenza, F1
Hudson, CJ1
Seeman, P1
Seeman, MV1
Castle, DJ1
Slott Jensen, JK1
Udawela, M1
Money, TT1
Neo, J1
Seo, MS1
Scarr, E1
Dean, B1
Everall, IP1
Yohn, SE1
Alberati, D1
Correa, M1
Salamone, JD1
Faaij, RA1
Ziere, G1
Zietse, R1
Van der Cammen, TJ1
Uezato, A1
Meador-Woodruff, JH1
McCullumsmith, RE1
Felthous, AR1
Wenger, PJ1
Hoevet, R1
Eggan, SM1
Stoyak, SR1
Verrico, CD1
Lewis, DA3
Onishi, H1
Wada, M2
Wada, T1
Ishida, M1
Kawanishi, C1
Mizuno, K1
Ito, H1
Narabayashi, M1
Sasaki, Y1
Morag, A1
Oved, K1
Gurwitz, D1
Truöl, S1
Von Hippel, C1
Raape, J1
König, F1
Markianos, M3
Hatzimanolis, J3
Lykouras, L3
LEHMANN, HE1
BAN, TA1
KATO, G1
GOZSY, B1
KATO, L1
BUIS, C1
FLOHIL, JM1
Matsumoto, M1
Konno, T1
Tamba, K1
Abe, T1
Kato, S1
Kajii, E1
Pongrac, JL1
Middleton, FA2
Peng, L1
Levitt, P2
Mirnics, K2
Schmitt, A1
Bertsch, T1
Henning, U1
Tost, H1
Klimke, A1
Henn, FA1
Falkai, P1
Grant, MJ1
Baldessarini, RJ1
McEvoy, JP1
Johnson, J1
Perkins, D1
Lieberman, JA1
Hamer, RM1
Keefe, RS1
Tohen, M1
Glick, ID1
Sharma, T1
Gareri, P1
De Fazio, P1
Cotroneo, A1
Lacava, R1
Gallelli, L1
De Fazio, S1
De Sarro, G1
Schuster, JP1
Buhl, C1
Archambaud, F1
Hardy, P1
Chouinard, G1
Prigent, A1
Corruble, E1
Schlösser, R1
Schlegel, S1
Hiemke, C1
Nickel, O1
Bockisch, A1
Rao, ML1
Hahn, K1
Oulis, P1
Christodoulou, G1
Ty, EB1
Rothner, AD1
Stanwood, GD1
Zwanzger, P1
Ella, R1
Keck, ME1
Rupprecht, R1
Padberg, F1
Tignol, J1
Bourgeois, M1
König, L2
Lange, E1
Brion, S1
Chevalier, JF1
Guerin, R1
Ginestet, D1
Maier, C1
Man, PL1
Dunlop, E1
Radzuweit, H1
Knorr, W1
Greger, J1
Glitschka, A1
Müller, K1
Holstein, AP1
Chen, CH1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicenter, Randomized, Double-Blind, Fixed-Dose, 6-Week Trial of the Efficacy and Safety of Asenapine Compared With Placebo Using Olanzapine Positive Control in Subjects With an Acute Exacerbation of Schizophrenia[NCT00156117]Phase 3417 participants (Actual)Interventional2005-05-12Completed
A Multicenter, Randomized, Double-Blind, Fixed-Dose, 6-Week Trial of the Efficacy and Safety of Asenapine Compared With Placebo Using Haloperidol Positive Control in Subjects With an Acute Exacerbation of Schizophrenia[NCT00156104]Phase 3460 participants (Actual)Interventional2005-07-01Completed
Aripiprazole for Pre-Existing Neuroleptic-Induced Tardive Dyskinesia: a Prospective 26-Week Observational Study[NCT00837707]Phase 425 participants (Anticipated)Interventional2008-06-30Recruiting
A Prospective, Double Blind, Randomized, Sham-Controlled, Clinical Trial to Evaluate The Safety And Efficacy Of Biometrics-Guided Magnetic EEG Resonance Therapy (MeRT) Treatment Of Post-Traumatic Stress Disorder With And Without Persistent Post-Concussive[NCT02990793]152 participants (Anticipated)Interventional2022-04-04Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for haloperidol and Depression, Involutional

ArticleYear
Neuroleptic malignant syndrome in children and adolescents.
    Journal of child neurology, 2001, Volume: 16, Issue:3

    Topics: Adolescent; Adult; Antipsychotic Agents; Child; Depressive Disorder, Major; Female; Haloperidol; Hum

2001

Trials

6 trials available for haloperidol and Depression, Involutional

ArticleYear
Depression treatment by withdrawal of short-term low-dose antipsychotic, a proof-of-concept randomized double-blind study.
    Journal of affective disorders, 2014, Volume: 166

    Topics: Adolescent; Adult; Antipsychotic Agents; Depressive Disorder, Major; Diagnostic and Statistical Manu

2014
Management of depressive symptoms in schizophrenia.
    Clinical schizophrenia & related psychoses, 2015, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Depressive Disorder, Major; Dibenzocyclohe

2015
Management of depressive symptoms in schizophrenia.
    Clinical schizophrenia & related psychoses, 2015, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Depressive Disorder, Major; Dibenzocyclohe

2015
Management of depressive symptoms in schizophrenia.
    Clinical schizophrenia & related psychoses, 2015, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Depressive Disorder, Major; Dibenzocyclohe

2015
Management of depressive symptoms in schizophrenia.
    Clinical schizophrenia & related psychoses, 2015, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Depressive Disorder, Major; Dibenzocyclohe

2015
Serotonergic and dopaminergic neuroendocrine responses of male depressive patients before and after a therapeutic ECT course.
    European archives of psychiatry and clinical neuroscience, 2002, Volume: 252, Issue:4

    Topics: Adult; Aged; Clomipramine; Depressive Disorder, Major; Dopamine Antagonists; Electroconvulsive Thera

2002
Relationship between prolactin responses to ECT and dopaminergic and serotonergic responsivity in depressed patients.
    European archives of psychiatry and clinical neuroscience, 2002, Volume: 252, Issue:4

    Topics: Adult; Aged; Clomipramine; Depressive Disorder, Major; Dopamine Antagonists; Electroconvulsive Thera

2002
Insight in first-episode psychosis.
    Psychological medicine, 2006, Volume: 36, Issue:10

    Topics: Adolescent; Adult; Antipsychotic Agents; Attitude to Health; Benzodiazepines; Brain; Cognition Disor

2006
Long term haloperidol therapy in outpatients.
    International journal of neuropsychiatry, 1967, Volume: 3

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Bipolar Disorder; Clinical Trials as Topic; Depressive Dis

1967

Other Studies

32 other studies available for haloperidol and Depression, Involutional

ArticleYear
Antidepressant, anti-amnesic and vasoprotective effect of Bombax costatum Pellegr. & Vuillet aqueous stem bark extract on chronic mild unpredictable stress induced in rat.
    Journal of ethnopharmacology, 2022, Jul-15, Volume: 293

    Topics: Acetylcholinesterase; Animals; Antidepressive Agents; Behavior, Animal; Bombax; Depression; Depressi

2022
[Malignant catatonia in dementia with Lewy Body successfully treated with sismotherapy: A case report].
    L'Encephale, 2020, Volume: 46, Issue:2

    Topics: Aged; Antipsychotic Agents; Catatonia; Critical Care; Delusions; Depressive Disorder, Major; Electro

2020
SELENBP1 expression in the prefrontal cortex of subjects with schizophrenia.
    Translational psychiatry, 2015, Aug-04, Volume: 5

    Topics: Animals; Antipsychotic Agents; Bipolar Disorder; Case-Control Studies; Chlorpromazine; Depressive Di

2015
Assessment of a glycine uptake inhibitor in animal models of effort-related choice behavior: implications for motivational dysfunctions.
    Psychopharmacology, 2017, Volume: 234, Issue:9-10

    Topics: Animals; Choice Behavior; Depressive Disorder, Major; Dopamine; Dopamine Antagonists; Dose-Response

2017
Delirium due to a drug-drug interaction of lithium and an NSAID.
    The journal of nutrition, health & aging, 2009, Volume: 13, Issue:3

    Topics: Accidental Falls; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Antidepressi

2009
Vesicular glutamate transporter mRNA expression in the medial temporal lobe in major depressive disorder, bipolar disorder, and schizophrenia.
    Bipolar disorders, 2009, Volume: 11, Issue:7

    Topics: Adult; Aged; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents;

2009
Acute psychosis associated with dissociated sleep-wakefulness state after mirtazapine treatment.
    Pharmacotherapy, 2010, Volume: 30, Issue:4

    Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Depressive Disorder, Major; Dreams; Ha

2010
Cannabinoid CB1 receptor immunoreactivity in the prefrontal cortex: Comparison of schizophrenia and major depressive disorder.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:10

    Topics: Adult; Aged; Analysis of Variance; Animals; Antipsychotic Agents; Case-Control Studies; Cohort Studi

2010
Diagnosis and treatment of akathisia in a cancer patient who cannot stand up or sit down, because of poor performance status: factors that make the diagnosis of akathisia difficult, and diagnosis clues.
    Palliative & supportive care, 2010, Volume: 8, Issue:4

    Topics: Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Bed Rest; Depressive Disorder, Major; Diagnosis

2010
Sex differences in human lymphoblastoid cells sensitivities to antipsychotic drugs.
    Journal of molecular neuroscience : MN, 2013, Volume: 49, Issue:3

    Topics: Anti-Inflammatory Agents; Antidepressive Agents; Antineoplastic Agents; Antipsychotic Agents; Cell D

2013
[Improvement of tardive dyskinesia after treatment with olanzapine].
    Psychiatrische Praxis, 2002, Volume: 29, Issue:6

    Topics: Affective Disorders, Psychotic; Aged; Benzodiazepines; Depressive Disorder, Major; Drug Therapy, Com

2002
POTENTIATION OF PHARMACOLOGICAL AND THERAPEUTIC ACTION OF PHENOTHIAZINES BY NYLIDRIN (ARLIDIN).
    Comprehensive psychiatry, 1964, Volume: 5

    Topics: Bipolar Disorder; Brain; Brain Damage, Chronic; Chlorprothixene; Depressive Disorder, Major; Dextran

1964
[CLINICAL EXPERIENCES WITH HALOPERIDOL (SERENASE)].
    Nederlands tijdschrift voor geneeskunde, 1964, Apr-18, Volume: 108

    Topics: Bipolar Disorder; Chlorpromazine; Chorea; Dementia; Depressive Disorder, Major; Epilepsy; Haloperido

1964
Two cases of deep vein thrombosis associated with antipsychotic drug use.
    Psychiatry and clinical neurosciences, 2004, Volume: 58, Issue:4

    Topics: Aged; Antipsychotic Agents; Chlorpromazine; Depressive Disorder, Major; Dose-Response Relationship,

2004
Heat shock protein 12A shows reduced expression in the prefrontal cortex of subjects with schizophrenia.
    Biological psychiatry, 2004, Dec-15, Volume: 56, Issue:12

    Topics: Adult; Animals; Antipsychotic Agents; Blotting, Northern; Case-Control Studies; Depressive Disorder,

2004
Increased serum S100B in elderly, chronic schizophrenic patients: negative correlation with deficit symptoms.
    Schizophrenia research, 2005, Dec-15, Volume: 80, Issue:2-3

    Topics: Aged; Antipsychotic Agents; Chronic Disease; Clozapine; Cognition Disorders; Depressive Disorder, Ma

2005
Possible improvement of neuroleptic-associated tardive dyskinesia during treatment with aripiprazole.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:11

    Topics: Antipsychotic Agents; Aripiprazole; Delusions; Depressive Disorder, Major; Dyskinesia, Drug-Induced;

2005
Anticholinergic drug-induced delirium in an elderly Alzheimer's dementia patient.
    Archives of gerontology and geriatrics, 2007, Volume: 44 Suppl 1

    Topics: Acute Disease; Aged, 80 and over; Alzheimer Disease; Amitriptyline; Antipsychotic Agents; Cholinergi

2007
Using striatal dopamine transporter single photon emission computed tomography imaging to rule out Dementia with Lewy Bodies in elderly patients with antipsychotic-induced parkinsonism.
    Psychiatry and clinical neurosciences, 2007, Volume: 61, Issue:2

    Topics: Aged; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Cyclohexanols; Depressive Diso

2007
[123I]IBZM SPECT in patients treated with typical and atypical neuroleptics: relationship to drug plasma levels and extrapyramidal side effects.
    Psychiatry research, 1997, Sep-29, Volume: 75, Issue:2

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benperidol; Benzamides; Bipolar Disorder;

1997
Prolactin secretion in response to haloperidol challenge in delusional (psychotic) and non-delusional depression.
    European psychiatry : the journal of the Association of European Psychiatrists, 2000, Volume: 15, Issue:8

    Topics: Adolescent; Adult; Aged; Delusions; Depressive Disorder, Major; Dopamine Antagonists; Female; Halope

2000
Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia.
    Molecular psychiatry, 2001, Volume: 6, Issue:3

    Topics: Adult; Animals; Antipsychotic Agents; Chromosomes, Human, Pair 1; Depressive Disorder, Major; Family

2001
Occurrence of delusions during repetitive transcranial magnetic stimulation (rTMS) in major depression.
    Biological psychiatry, 2002, Apr-01, Volume: 51, Issue:7

    Topics: Delusions; Depressive Disorder, Major; Dopamine; Electric Stimulation Therapy; Electromagnetic Field

2002
[Disinhibition and its risks].
    L'Encephale, 1978, Volume: 4, Issue:5 Suppl

    Topics: Adjustment Disorders; Alcoholism; Antidepressive Agents; Depressive Disorder, Major; Haloperidol; Hu

1978
[Long-term treatment with neuroleptics in schizophrenic and paraphrenic psychoses].
    Zeitschrift fur arztliche Fortbildung, 1977, Apr-15, Volume: 71, Issue:8

    Topics: Delayed-Action Preparations; Depressive Disorder, Major; Fluphenazine; Haloperidol; Humans; Schizoph

1977
[Significance and advantages of Orap in the ambulatory care of schizophrenic psychoses].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1976, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Cyclothymic Disorder; Depression; Depressive Disorder, Maj

1976
[Chemotherapy of melancholia by sequential neuroleptic-viloxazine association].
    L'Encephale, 1976, Volume: 2, Issue:3

    Topics: Adjustment Disorders; Adult; Bipolar Disorder; Chlorpromazine; Depression; Depressive Disorder, Majo

1976
[Vital disorders of the mouth (glossodynia) in depressive involutional psychoses].
    Der Nervenarzt, 1986, Volume: 57, Issue:2

    Topics: Aged; Amitriptyline; Chlorpromazine; Depressive Disorder, Major; Drug Therapy, Combination; Female;

1986
Long-term effects of haloperidol.
    Diseases of the nervous system, 1973, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Back Pain; Basal Ganglia Diseases; Bipolar Disorder; Depression; Depressive Disor

1973
[Influencing of biological and immunologic pregnancy reactions by psychotropic drugs].
    Endokrinologie, 1969, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Aged; Butyrophenones; Chlorpromazine; Dementia; Depressive Disorder, Major; Dysau

1969
[On the position of the butyrophenone derivative Haloperidol in psychiatric treatment].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1968, Volume: 20, Issue:7

    Topics: Adult; Aged; Bipolar Disorder; Catatonia; Child; Depression; Depressive Disorder, Major; Extrapyrami

1968
Haloperidol--a preliminary clinical study.
    The American journal of psychiatry, 1965, Volume: 122, Issue:4

    Topics: Depressive Disorder, Major; Extrapyramidal Tracts; Haloperidol; Humans; Paranoid Disorders; Schizoph

1965